Plant Comparison
Cumin vs Chamomile
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Cumin and Chamomile: they share 9 indicated uses (arthritis / joint pain, bloating, indigestion, …); 4 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Cumin | Chamomile | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 9/10 | 5/10 | Stronger for Cumin |
| Bloating | 10/10 | 1/10 | Stronger for Cumin |
| Indigestion | 10/10 | 1/10 | Stronger for Cumin |
| Infection (general) | 9/10 | 1/10 | Stronger for Cumin |
| Inflammation (general) | 9/10 | 1/10 | Stronger for Cumin |
| Menstrual cramps | 10/10 | 7/10 | Stronger for Cumin |
| Muscle spasm | 10/10 | 1/10 | Stronger for Cumin |
| Skin irritation | 9/10 | 1/10 | Stronger for Cumin |
| Wounds | 9/10 | 1/10 | Stronger for Cumin |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Cuminaldehyde (4-isopropylbenzaldehyde) is the dominant constituent of cumin-seed essential oil (around two-thirds of the oil) and the main driver of its antimicrobial, antifungal (anti-aflatoxigenic) and antioxidant activity.
The volatile oil, concentrated in the flower head, gives chamomile its characteristic blue colour (chamazulene) and much of its anti-inflammatory activity (alpha-bisabolol).
Apigenin is considered a key contributor to chamomile's sedative/anxiolytic activity via GABA-A receptor binding.
Minor constituents (e.g. herniarin, umbelliferone) contributing to the mild antispasmodic action.
Contribute to the soothing, demulcent effect on irritated mucous membranes.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from digestive action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from analgesic action
inferred from digestive action
inferred from vulnerary action
inferred from analgesic action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from sedative action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from antimicrobial action
Safety, Cautions & Contraindications
Food amounts are generally considered safe; in the US it’s listed as GRAS as a spice/flavoring (LactMed, 2025).
Allergy risk: cumin can trigger allergic reactions in sensitive people; cross-reactivity is reported within Apiaceae spices (e.g., celery/coriander/fennel/cumin) and in “pollen–spice” allergy patterns (Lisiecka et al., 2025; Berghea et al., 2025).
Duke (2002) rates cumin as +++ and notes carminative, digestive, and aperitif activities at experimental levels (score 1). The plant demonstrates estrogenic activity in animal studies and has antifungal and antioxidant properties. Photodermatitic potential (phototoxicity) of the essential oil is noted — users should avoid sun exposure after topical application. Duke advises caution in pregnancy due to potential emmenagogue and antifertility effects at high medicinal doses (Duke, 2002).
Generally considered very safe when used as tea or topical preparations.Allergy risk: People allergic to ragweed, daisies, or other Asteraceae plants may react (itching, rash).Blood thinners: Chamomile may slightly enhance effects of anticoagulants—use large amounts cautiously.Pregnancy: Normal tea amounts are usually considered safe, but concentrated extracts should be used with caution.Topical use: Rare skin irritation in sensitive individuals.
Duke (2002) rates German chamomile (Matricaria chamomilla) highly for anti-inflammatory, antispasmodic, and wound-healing activities. The essential oil contains the potent anti-inflammatory compound alpha-bisabolol. Chamomile is Commission E approved for digestive complaints and topical wound care. Dose: 3 g dried flower heads per cup of water, three times daily. Alpha-bisabolol is noted as one of the most active natural anti-inflammatory compounds known. Caution: chamomile belongs to the Asteraceae family and can cause allergic reactions in individuals sensitive to ragweed, chrysanthemums, or related plants (Duke, 2002).
Generally very safe. Rare allergic reactions in individuals sensitive to the Asteraceae family (ragweed, chrysanthemums). May cause contact dermatitis with topical essential oil use. Avoid very high doses in pregnancy. Well tolerated by children in appropriate amounts.
Scented mayweed (Matricaria chamomilla) shares the same species as German chamomile (see German Chamomile entry above). Duke (2002) provides the same clinical support: Commission E approves it for dyspeptic complaints (orally) and skin and mucous membrane inflammation (topically). Anti-inflammatory, antispasmodic, and wound-healing activities are well-established (Duke, 2002).
External Ids
Botanical Description
Slender annual herb with finely divided, thread-like leaves similar to dill or fennel but smaller. Small white or pale pink flowers are borne in small compound umbels, followed by small, ridged, boat-shaped, strongly aromatic seeds.
Aromatic annual herb, 15-60 cm tall, with an erect, much-branched, hairless stem. Leaves are alternate and finely bi- to tripinnately divided into thread-like segments, giving a feathery appearance. Flower heads are small daisy-like composites, 1-2.5 cm across, with white ray florets that reflex sharply downward as the flower matures around a conical, hollow, yellow disc of tubular florets - the hollow, conical receptacle is a key feature distinguishing German chamomile from similar-looking daisies. The fruit is a tiny ribbed achene without a pappus.[1, 10]
Habitat
Believed native to the eastern Mediterranean and Central Asia; cultivated widely in warm, dry climates including India, the Middle East and North Africa as a major spice crop.
Harvesting
The seed heads are cut when the fruit has ripened but before it shatters, usually in mid- to late summer, then dried and threshed.
Flower heads are hand- or machine-harvested at full bloom, when the ray florets are horizontal and just beginning to reflex, then dried quickly at low temperature and out of direct light to preserve the volatile oil.[6]
Traditional Uses
Cumin seed has an ancient culinary and medicinal history across the Middle East, South Asia and the Mediterranean as a warming digestive carminative for indigestion, bloating and cramping, and is one of the most widely used spices worldwide.
Chamomile is one of the most widely used medicinal herbs in the world, with a long traditional history as a mild digestive, calming and anti-inflammatory remedy - taken as a tea for indigestion, cramping, and restlessness or poor sleep, and applied topically for skin and mucous-membrane inflammation and wound healing. Modern reviews confirm anti-inflammatory, antispasmodic, sedative/anxiolytic and antimicrobial pharmacological activity supporting these traditional uses.[1, 6, 10]
Lookalikes Review
Preparations
Not documented
Dried flower heads steeped in hot water, the classic way of taking chamomile for digestive complaints, mild anxiety and sleep support.
Steam-distilled from the flower heads; a concentrated source of alpha-bisabolol and chamazulene, used mainly in topical and aromatherapy preparations.
Concentrated extract or infused oil applied to skin, or as a compress - a randomised controlled trial found a topical chamomile oil preparation effective for knee osteoarthritis pain.
Dosage
References
Not documented
Drug Class Interactions
Not documented
Pairings
Not documented
Chamomile and valerian are both traditional mild sedatives for restlessness and poor sleep; taken together they may enhance calming and sleep effects but also add to drowsiness.[23]
Chamomile and lemon balm are both gentle calming herbs commonly combined for stress and sleep; used together their mild sedative effects may add up.[23]
References & Sources
- Ben Miri, Y. and Djenane, D (2018) 'Evaluation of Protective Impact of Algerian Cuminum cyminum L. and Coriandrum sativum L. Essential Oils on Aspergillus flavus Growth and Aflatoxin B1 Production', Pakistan Journal of Biological Sciences, 21(2), pp. 67--77. doi:10.3923/pjbs.2018.67.77 Preclinical
https://doi.org/10.3923/pjbs.2018.67.77 - Allaq, A.A. and Sidik, N.J (2020) 'Cumin (Cuminum cyminum L.): A review of its ethnopharmacology, phytochemistry and biological activities'. Available at: https://bmrat.org/index.php/BMRAT/article/view/634 Traditional / reference
https://bmrat.org/index.php/BMRAT/article/view/634 - Berghea, E.C. et al (2025) 'Spices, herbs and allergic reactions in children: myth or reality?'. doi:10.3389/falgy.2025.1698559/full Clinical study
https://doi.org/10.3389/falgy.2025.1698559/full - Britannica (2025) 'Cumin'. Available at: https://www.britannica.com/plant/cumin Traditional / reference
https://www.britannica.com/plant/cumin - EUR-Lex (2015) 'Official Journal of the European Union C 76/2015 (Latvian text; includes “Romiešu ķimenes (cumin)'. Available at: https://eur-lex.europa.eu/legal-content/LV/TXT/HTML/?uri=OJ%3AC%3A2015%3A076%3AFULL Traditional / reference
https://eur-lex.europa.eu/legal-content/LV/TXT/HTML/?uri=OJ%3AC%3A2015%3A076%3AFULL - EUR-Lex (2020) 'Official Journal of the European Union C 108/2020 (Latvian text; includes “kumins (romiešu ķimenes)'. Available at: https://eur-lex.europa.eu/legal-content/LV/TXT/HTML/?uri=CELEX%3A52020XC0401%2804%29 Traditional / reference
https://eur-lex.europa.eu/legal-content/LV/TXT/HTML/?uri=CELEX%3A52020XC0401%2804%29 - http://letonika.lv/ (2021) 'Latviešu—angļu vārdnīca: ķimenes (includes “Romiešu ķimenes = cumin'. Available at: http://letonika.lv/ Traditional / reference
http://letonika.lv/ - Karimian, J. et al (2021) 'The effects of cumin (Cuminum cyminum L.) supplementation on glycemic indices: a systematic review and meta-analysis'. doi:10.1002/ptr.7075 Meta-analysis / review
https://doi.org/10.1002/ptr.7075 - KPBS (2015) 'Cumin: The Ancient Spice That'. Available at: https://www.kpbs.org/news/2015/03/11/cumin-the-ancient-spice-thats-traveled-the-globe Traditional / reference
https://www.kpbs.org/news/2015/03/11/cumin-the-ancient-spice-thats-traveled-the-globe - LactMed (2025) 'Cumin'. Available at: https://www.ncbi.nlm.nih.gov/books/NBK501873/ Traditional / reference
https://www.ncbi.nlm.nih.gov/books/NBK501873/ - Lisiecka, M.F. et al (2025) 'Allergic reactions to spices: a review of sensitivities to pepper, cumin, oregano, anise, mustard and other spices'. Available at: https://pubmed.ncbi.nlm.nih.gov/40341008/ Traditional / reference
https://pubmed.ncbi.nlm.nih.gov/40341008/ - Liu, M. et al (2025) 'Potential benefits of Cuminum cyminum L'. doi:10.3389/fnut.2025.1618108/full Meta-analysis / review
https://doi.org/10.3389/fnut.2025.1618108/full - Morshedi, D. et al (2015) 'Cuminaldehyde as the Major Component of Cuminum cyminum…', 80(10), pp. H2336--H2345. doi:10.1111/1750-3841.13016 Preclinical
https://doi.org/10.1111/1750-3841.13016 - Nabhan, G.P (2014) 'Cumin, Camels, and Caravans: A Spice Odyssey'. Available at: https://www.ucpress.edu/book/9780520379244/cumin-camels-and-caravans Traditional / reference
https://www.ucpress.edu/book/9780520379244/cumin-camels-and-caravans - Nouri, A. et al (2024) 'Phytochemical composition… (includes GC–MS profile of cumin seed essential oil)'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11606850/ Traditional / reference
https://pmc.ncbi.nlm.nih.gov/articles/PMC11606850/ - PubChem (n.d.). Available at: https://pubchem.ncbi.nlm.nih.gov/compound/Cumin-Oil Traditional / reference
https://pubchem.ncbi.nlm.nih.gov/compound/Cumin-Oil - Royal Botanic Gardens, Kew (n.d.) 'Cuminum cyminum L'. Available at: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:840882-1 Traditional / reference
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:840882-1 - SekoEko (n.d.) 'Kumīns, ķimenes un citi līdzinieki!'. Available at: https://sekoeko.lv/lv/kumins-kimenes-un-citi-lidzinieki Traditional / reference
https://sekoeko.lv/lv/kumins-kimenes-un-citi-lidzinieki - Tavakoli-Rouzbehani, O.M. et al (2022) 'The effects of cumin supplementation on lipid parameters: a systematic review and meta-analysis of RCTs'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC9881733/ Meta-analysis / review
https://pmc.ncbi.nlm.nih.gov/articles/PMC9881733/ - Vikipēdija (n.d.). Available at: https://lv.wikipedia.org/wiki/Kum%C4%ABns Traditional / reference
https://lv.wikipedia.org/wiki/Kum%C4%ABns - Wikisource (2018) '1911 Encyclopædia Britannica: Cumin'. Available at: https://en.wikisource.org/wiki/1911_Encyclop%C3%A6dia_Britannica/Cumin Traditional / reference
https://en.wikisource.org/wiki/1911_Encyclop%C3%A6dia_Britannica/Cumin - Amin, E.A., Ismail, E., Mahboobeh, R. and Tabandeh, S (2024) 'The effect of Cuminum cyminum on the return of bowel motility after abdominal surgery: a triple-blind randomized clinical trial', BMC Complementary Medicine and Therapies, 24(1). doi:10.1186/s12906-024-04530-1 Randomized trial
https://doi.org/10.1186/s12906-024-04530-1 - Hadi, A., Mohammadi, H., Hadi, Z., Roshanravan, N. and Kafeshani, M (2018) 'Cumin (Cuminum cyminum L.) is a safe approach for management of lipid parameters: A systematic review and meta-analysis of randomized controlled trials', Phytotherapy Research, 32(11), pp. 2146--2154. doi:10.1002/ptr.6162 Meta-analysis / review
https://doi.org/10.1002/ptr.6162 - Tavakoli-Rouzbehani, O.M., Faghfouri, A.H., Anbari, M., Papi, S., Shojaei, F.S., Ghaffari, M. and Alizadeh, M (2021) 'The effects of Cuminum cyminum on glycemic parameters: A systematic review and meta-analysis of controlled clinical trials', Journal of Ethnopharmacology, pp. 2021. doi:10.1016/j.jep.2021.114510 Meta-analysis / review
https://doi.org/10.1016/j.jep.2021.114510 - Karimian, J., Farrokhzad, A. and Jalili, C (2021) 'The effect of cumin (Cuminum cyminum L.) supplementation on glycemic indices: A systematic review and meta-analysis of randomized controlled trials', Phytotherapy Research, 35(8), pp. 4127--4135. doi:10.1002/ptr.7075 Meta-analysis / review
https://doi.org/10.1002/ptr.7075 - Morovati, A., Pourghassem Gargari, B. and Sarbakhsh, P (2019) 'Effects of cumin (Cuminum cyminum L.) essential oil supplementation on metabolic syndrome components: A randomized, triple-blind, placebo-controlled clinical trial', Phytotherapy Research, 33(12), pp. 3261--3269. doi:10.1002/ptr.6500 Randomized trial
https://doi.org/10.1002/ptr.6500 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
- El Mihyaoui, A., Esteves da Silva, J.C.G., Charfi, S., Candela Castillo, M.E. and others (2022) 'Chamomile (Matricaria chamomilla L.): A Review of Ethnomedicinal Use, Phytochemistry and Pharmacological Uses', Life, 12(4), pp. 479. doi:10.3390/life12040479 Meta-analysis / review
https://doi.org/10.3390/life12040479 - Kazemi, A., Shojaei-Zarghani, S., Eskandarzadeh, P. and Hashempur, M.H (2024) 'Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials', Complementary Therapies in Medicine, 84, pp. 103071. doi:10.1016/j.ctim.2024.103071 Meta-analysis / review
https://doi.org/10.1016/j.ctim.2024.103071 - Mao, J.J., Xie, S.X., Keefe, J.R., Soeller, I. and others (2016) 'Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial', Phytomedicine, 23(14), pp. 1735-1742. doi:10.1016/j.phymed.2016.10.012 Randomized trial
https://doi.org/10.1016/j.phymed.2016.10.012 - Amsterdam, J.D., Li, Q.S., Xie, S.X. and Mao, J.J (2020) 'Putative Antidepressant Effect of Chamomile (Matricaria chamomilla L.) Oral Extract in Subjects with Comorbid Generalized Anxiety Disorder and Depression', Journal of Alternative and Complementary Medicine, 26(9), pp. 813-819. doi:10.1089/acm.2019.0252 Clinical study
https://doi.org/10.1089/acm.2019.0252 - McKay, D.L. and Blumberg, J.B (2006) 'A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.)', Phytotherapy Research, 20(7), pp. 519-530. doi:10.1002/ptr.1900 Meta-analysis / review
https://doi.org/10.1002/ptr.1900 - Dai, Y.L., Li, Y., Wang, Q., Niu, F.J. and others (2022) 'Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies', Molecules, 28(1), pp. 133. doi:10.3390/molecules28010133 Meta-analysis / review
https://doi.org/10.3390/molecules28010133 - Miraj, S. and Alesaeidi, S (2016) 'A systematic review study of therapeutic effects of Matricaria recutita chamomile (chamomile)', Electronic Physician, 8(9), pp. 3024-3031. doi:10.19082/3024 Meta-analysis / review
https://doi.org/10.19082/3024 - Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K. and others (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
https://doi.org/10.1097/JCP.0b013e3181ac935c - Park, S.H., Kim, D.S., Oh, J., Geum, J.H. and others (2021) 'Matricaria chamomilla (Chamomile) Ameliorates Muscle Atrophy in Mice by Targeting Protein Catalytic Pathways, Myogenesis, and Mitochondrial Dysfunction', The American Journal of Chinese Medicine, 49(6), pp. 1493-1514. doi:10.1142/S0192415X21500701 Preclinical
https://doi.org/10.1142/S0192415X21500701 - Singh, O., Khanam, Z., Misra, N. and Srivastava, M.K (2011) 'Chamomile (Matricaria chamomilla L.): An overview', Pharmacognosy Reviews, 5(9), pp. 82-95. doi:10.4103/0973-7847.79103 Meta-analysis / review
https://doi.org/10.4103/0973-7847.79103 - Amsterdam, J.D., Shults, J., Soeller, I., Mao, J.J., Rockwell, K. and Newberg, A.B (2012) 'Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study', Alternative Therapies in Health and Medicine, 18(5), pp. 44-49. Randomized trial
https://scholar.google.com/scholar?q=Chamomile%20%28Matricaria%20recutita%29%20may%20provide%20antidepressant%20activity%20in%20anxious%2C%20depressed%20humans%3A%20an%20exploratory%20study - Shoara, R., Hashempur, M.H., Ashraf, A., Salehi, A., Dehshahri, S. and Habibagahi, Z (2015) 'Efficacy and safety of topical Matricaria chamomilla L. (chamomile) oil for knee osteoarthritis: a randomized controlled clinical trial', Complementary Therapies in Clinical Practice, 21(3), pp. 181-187. doi:10.1016/j.ctcp.2015.06.003 Randomized trial
https://doi.org/10.1016/j.ctcp.2015.06.003 - Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2016) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
https://doi.org/10.1016/j.nut.2015.07.011 - Niazi, A. and Moradi, M (2021) 'The effect of chamomile on pain and menstrual bleeding in primary dysmenorrhea: a systematic review', International Journal of Community Based Nursing and Midwifery, 9(3), pp. 174-186. doi:10.30476/ijcbnm.2021.87219.1417 Meta-analysis / review
https://doi.org/10.30476/ijcbnm.2021.87219.1417 - European Medicines Agency (2015) 'European Union herbal monograph on Matricaria recutita L., flos'. Traditional / reference
https://scholar.google.com/scholar?q=European%20Union%20herbal%20monograph%20on%20Matricaria%20recutita%20L.%2C%20flos - Hoffmann, D (2003) 'Medical Herbalism'. Traditional / reference
https://scholar.google.com/scholar?q=Medical%20Herbalism - Padula, M.C (2006) 'Chamomile: industrial profiles'. Traditional / reference
https://scholar.google.com/scholar?q=Chamomile%3A%20industrial%20profiles - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Srivastava, J.K., Shankar, E. and Gupta, S (2010) 'Chamomile: a herbal medicine of the past with bright future', 3(6), pp. 895--901. doi:10.3892/mmr.2010.377 Traditional / reference
https://doi.org/10.3892/mmr.2010.377 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Segal, R. and Pilote, L (2006) 'Warfarin interaction with Matricaria chamomilla', CMAJ, 174(9), pp. 1281-1282. doi:10.1503/cmaj.051191 Clinical study
https://doi.org/10.1503/cmaj.051191 - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003 - Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K., Mao, J.J. and Shults, J (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
https://doi.org/10.1097/JCP.0b013e3181ac935c - Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2015) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
https://doi.org/10.1016/j.nut.2015.07.011
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.