Plant Comparison

Borage vs Chamomile

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ABorageBorago officinalisBoraginaceaeFull monograph →
Plant BChamomileMatricaria chamomillaAsteraceaeFull monograph →

At a glance

Borage and Chamomile: they share 9 indicated uses (arthritis / joint pain, back pain, bloating, …); 4 pharmacological actions in common.

BorageChamomile
Constituents34
Pharmacological actions711
Indicated uses1318
Safety notes24
Cited sources2025
Indicated uses
Only Borage
Cancer (anticancer research)Cold & fluImmune supportRespiratory support
Shared (9)
Arthritis / joint painBack painBloatingEczemaHeadacheIndigestionInflammation (general)Pain (general)Skin irritation
Only Chamomile
BruisingInfection (general)Insomnia / sleeplessnessMenstrual crampsMuscle spasmWoundsAnxietyLow mood / depressionBlood sugar / diabetes support
Pharmacological actions
Only Borage
Anticancer (preclinical)AntioxidantImmunomodulator / immune support
Shared (4)
Analgesic (pain relief)Anti-inflammatoryDigestive aidEmollient / skin-soothing
Only Chamomile
AntimicrobialAntispasmodicSedative / sleep supportVulnerary (wound healing)Anxiolytic / calmingAntidepressant / mood supportAntidiabetic (blood-sugar lowering)

Evidence face-off — shared uses

ConditionBorageChamomileVerdict
Arthritis / joint pain1/105/10Stronger for Chamomile
Back pain1/101/10Comparable evidence
Bloating1/101/10Comparable evidence
Eczema1/101/10Comparable evidence
Headache1/101/10Comparable evidence
Indigestion1/101/10Comparable evidence
Inflammation (general)1/101/10Comparable evidence
Pain (general)1/101/10Comparable evidence
Skin irritation1/101/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Gamma-linolenic acid (GLA) seed oil[1]

Borage seed oil has one of the highest known GLA contents of any plant oil (typically 20-26%), the basis of its anti-inflammatory reputation.

Gamma-linolenic acid (GLA)
Pyrrolizidine alkaloids[1]

Unsaturated pyrrolizidine alkaloids present in the whole herb are hepatotoxic and genotoxic on cumulative exposure, limiting internal whole-herb use; the refined seed oil is largely free of them.

Alkaloids
Mucilage and tannins[1]

Contribute to the plant's traditional demulcent and astringent properties.

MucilageTannins
Essential oil (alpha-bisabolol, chamazulene)[1, 6]

The volatile oil, concentrated in the flower head, gives chamomile its characteristic blue colour (chamazulene) and much of its anti-inflammatory activity (alpha-bisabolol).

Essential (volatile) oilAlpha-bisabololChamazulene
Flavonoids (apigenin, quercetin, luteolin, rutin)[10]

Apigenin is considered a key contributor to chamomile's sedative/anxiolytic activity via GABA-A receptor binding.

ApigeninQuercetinLuteolinRutinFlavonoids
Coumarins[6]

Minor constituents (e.g. herniarin, umbelliferone) contributing to the mild antispasmodic action.

Coumarins
Mucilage polysaccharides[10]

Contribute to the soothing, demulcent effect on irritated mucous membranes.

MucilagePolysaccharides

Pharmacological Actions

Analgesic (pain relief)[15, 16, 17]
Anti-inflammatory[1, 6, 12, 15, 16, 17]
Anticancer (preclinical)[7]
Antioxidant[1, 5, 7, 10, 15, 16, 17]
Digestive aid[4, 15, 16, 17]
Emollient / skin-soothing[5, 15, 16, 17]
Immunomodulator / immune support[12, 15, 16, 17]
Analgesic (pain relief)[12, 14, 15, 16, 17, 18, 19]
Anti-inflammatory[1, 5, 6, 7, 10, 12, 15, 16, 17, 18, 19]
Antimicrobial[1, 15, 16, 17, 18, 19]
Antispasmodic[1, 5, 6, 14, 15, 16, 17, 18, 19]

Antispasmodic (cramp easing)

Digestive aid[1, 5, 10, 15, 16, 17, 18, 19]
Emollient / skin-soothing[15, 16, 17, 18, 19]
Sedative / sleep support[1, 2, 3, 4, 7, 8, 10, 15, 16, 17, 18, 19]
Vulnerary (wound healing)[15, 16, 17, 18, 19]
Anxiolytic / calming[3, 8]
Antidepressant / mood support[11]
Antidiabetic (blood-sugar lowering)[13]

Traditional & Indicated Uses

Arthritis / joint pain[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Back pain[15, 16, 17]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Back pain
Bloating[15, 16, 17]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Cancer (anticancer research)[7]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Cold & flu[15, 16, 17]Traditional · 1/10

inferred from immunomodulator action

Evidence: 1
Label: Cold & flu
Eczema[15, 16, 17]Traditional · 1/10

inferred from emollient action

Evidence: 1
Label: Eczema
Headache[15, 16, 17]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Headache
Immune support[15, 16, 17]Traditional · 1/10
Evidence: 1
Label: Immune support
Indigestion[15, 16, 17]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Indigestion
Inflammation (general)[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Pain (general)[15, 16, 17]Traditional · 1/10
Evidence: 1
Label: Pain (general)
Respiratory support[15, 16, 17]Traditional · 1/10
Evidence: 1
Label: Respiratory support
Skin irritation[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Arthritis / joint pain[12, 15, 16, 17, 18, 19]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Arthritis / joint pain
Back pain[15, 16, 17, 18, 19]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Back pain
Bloating[15, 16, 17, 18, 19]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Bruising[15, 16, 17, 18, 19]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Eczema[15, 16, 17, 18, 19]Traditional · 1/10

inferred from emollient action

Evidence: 1
Label: Eczema
Headache[15, 16, 17, 18, 19]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Headache
Indigestion[15, 16, 17, 18, 19]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Indigestion
Infection (general)[15, 16, 17, 18, 19]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[15, 16, 17, 18, 19]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Insomnia / sleeplessness[2, 15, 16, 17, 18, 19]Good · 7/10

inferred from sedative action

Evidence: 7
Label: Insomnia / sleeplessness
Menstrual cramps[14, 15, 16, 17, 18, 19]Good · 7/10

inferred from antispasmodic action

Evidence: 7
Label: Menstrual cramps
Muscle spasm[15, 16, 17, 18, 19]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Muscle spasm
Pain (general)[15, 16, 17, 18, 19]Traditional · 1/10
Evidence: 1
Label: Pain (general)
Skin irritation[15, 16, 17, 18, 19]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[15, 16, 17, 18, 19]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Anxiety[3, 8]Moderate · 6/10
Evidence: 6
Label: Anxiety
Low mood / depression[11]Moderate · 5/10
Evidence: 5
Label: Low mood / depression
Blood sugar / diabetes support[13]Moderate · 5/10
Evidence: 5
Label: Blood sugar / diabetes support

Safety, Cautions & Contraindications

Safety note[15, 16, 17]Serious

Pyrrolizidine alkaloids (PAs): Many Boraginaceae can produce PAs; unsaturated PAs are hepatotoxic and genotoxic (risk increases with cumulative exposure). Borage as food/tea: PA presence in borage consumed as herb/tea has been specifically studied; EU has set PA maximum levels for certain foods including borage (context for why sourcing/limits matter). Pregnancy/breastfeeding: avoid internal use of borage herb products due to PA-related concerns and risk uncertainty. Liver disease / long-term use: avoid (PA risk + cumulative exposure logic). Seed oil vs herb: refined/quality-controlled seed oil is generally the preferred form when borage is used medicinally, because the main target compound is GLA; however, product quality and contamination control still matter. Drug interactions (caution): GLA oils have been discussed with anticoagulants (bleeding risk caution is better established for evening primrose oil; borage oil is often grouped in the same “GLA oil” category). Use caution if on anticoagulants/antiplatelets.

Safety note[15, 16, 17, 18]Serious

Duke (2002) rates borage as a single-plus herb (+) with predominantly folklore-level evidence. Borage seed oil is rich in gamma-linolenic acid (GLA) and has been used for inflammatory conditions such as arthritis and PMS, and for cardiovascular support; typical dose is one 300 mg softgel containing 24% GLA or 2-4 ml liquid leaf extract. Commission E does not approve borage for any indication, and the herb contains hepatotoxic and carcinogenic pyrrolizidine alkaloids, making long-term use inadvisable (Duke, 2002).

Safety note[15, 16, 17, 18, 19]Caution

Generally considered very safe when used as tea or topical preparations.Allergy risk: People allergic to ragweed, daisies, or other Asteraceae plants may react (itching, rash).Blood thinners: Chamomile may slightly enhance effects of anticoagulants—use large amounts cautiously.Pregnancy: Normal tea amounts are usually considered safe, but concentrated extracts should be used with caution.Topical use: Rare skin irritation in sensitive individuals.

Safety note[15, 16, 17, 18, 19, 20]Caution

Duke (2002) rates German chamomile (Matricaria chamomilla) highly for anti-inflammatory, antispasmodic, and wound-healing activities. The essential oil contains the potent anti-inflammatory compound alpha-bisabolol. Chamomile is Commission E approved for digestive complaints and topical wound care. Dose: 3 g dried flower heads per cup of water, three times daily. Alpha-bisabolol is noted as one of the most active natural anti-inflammatory compounds known. Caution: chamomile belongs to the Asteraceae family and can cause allergic reactions in individuals sensitive to ragweed, chrysanthemums, or related plants (Duke, 2002).

Safety note[15, 16, 17, 18, 19]Caution

Generally very safe. Rare allergic reactions in individuals sensitive to the Asteraceae family (ragweed, chrysanthemums). May cause contact dermatitis with topical essential oil use. Avoid very high doses in pregnancy. Well tolerated by children in appropriate amounts.

Safety note[15, 16, 17, 18, 19, 20]Info

Scented mayweed (Matricaria chamomilla) shares the same species as German chamomile (see German Chamomile entry above). Duke (2002) provides the same clinical support: Commission E approves it for dyspeptic complaints (orally) and skin and mucous membrane inflammation (topically). Anti-inflammatory, antispasmodic, and wound-healing activities are well-established (Duke, 2002).

External Ids

Gbif: 2926110
Powo: urn:lsid:ipni.org:names:113618-1
Wikidata: Q147075
Gbif: 8370958
Wikidata: Q28437

Botanical Description

Robust, bristly annual herb with hollow, branching stems covered in coarse, stiff hairs. The leaves are large, oval and wrinkled, also coarsely hairy, and smell of cucumber when crushed. The flowers are strikingly bright blue, star-shaped with five pointed petals and a prominent black central cone of anthers, borne in nodding clusters.[1]

Height: 30-100 cm
Habit: Robust, bristly, branching annual herb
Leaves: Large, oval, wrinkled, coarsely hairy, smelling of cucumber when crushed
Flowers: Bright blue, star-shaped, five-pointed, with a prominent black central cone, in nodding clusters
Stem: Hollow, branching, covered in coarse stiff hairs
Root: Shallow taproot
Fruit: Small, dark, oily nutlet (seed)
Flowering Period: June-September

Aromatic annual herb, 15-60 cm tall, with an erect, much-branched, hairless stem. Leaves are alternate and finely bi- to tripinnately divided into thread-like segments, giving a feathery appearance. Flower heads are small daisy-like composites, 1-2.5 cm across, with white ray florets that reflex sharply downward as the flower matures around a conical, hollow, yellow disc of tubular florets - the hollow, conical receptacle is a key feature distinguishing German chamomile from similar-looking daisies. The fruit is a tiny ribbed achene without a pappus.[1, 10]

Height: 15-60 cm
Habit: Erect, much-branched, aromatic annual herb
Leaves: Alternate, finely 2-3-pinnately divided into thread-like segments
Flowers: Small daisy-like heads with downward-reflexed white ray florets around a conical hollow yellow disc
Stem: Erect, much-branched, hairless
Root: Slender taproot
Fruit: Tiny ribbed achene, no pappus
Flowering Period: May-August

Habitat

Grows readily on disturbed, nutrient-rich ground, gardens, waste places and field margins; native to the Mediterranean region and widely naturalised and cultivated across Europe and elsewhere as a culinary and oil-seed crop.[1]

Native to Europe and western Asia and now naturalised worldwide, growing on disturbed, sunny ground - arable field margins, waste places, roadsides and sandy or loamy soils; widely cultivated as a medicinal crop.[1, 6]

Harvesting

Leaves and flowers are picked fresh through the growing season, at their best just as the flowers open; the seed is collected in late summer once the seed heads have dried, pressed for its gamma-linolenic-acid-rich oil.[1]

Parts: Flower, Leaf, Seed, Stem
Season: Leaf and flower through summer; seed in late summer

Flower heads are hand- or machine-harvested at full bloom, when the ray florets are horizontal and just beginning to reflex, then dried quickly at low temperature and out of direct light to preserve the volatile oil.[6]

Parts: Flower heads
Season: Late spring to summer, at full bloom

Traditional Uses

Borage has a long folk reputation, reflected in the old saying 'borage for courage', as a mood-lifting, cooling herb for feverish colds and respiratory complaints, and as a digestive and anti-inflammatory remedy; the fresh leaves and flowers have also been used culinarily. Modern use is centred on the seed oil, rich in gamma-linolenic acid (GLA), for inflammatory and skin conditions.[1]

Chamomile is one of the most widely used medicinal herbs in the world, with a long traditional history as a mild digestive, calming and anti-inflammatory remedy - taken as a tea for indigestion, cramping, and restlessness or poor sleep, and applied topically for skin and mucous-membrane inflammation and wound healing. Modern reviews confirm anti-inflammatory, antispasmodic, sedative/anxiolytic and antimicrobial pharmacological activity supporting these traditional uses.[1, 6, 10]

Preparations

Seed oil[1]

Cold-pressed seed oil, standardised for GLA content, taken as capsules; the preferred modern medicinal form, since the whole herb carries pyrrolizidine-alkaloid caution.

Infusion[1]

Dried leaf infused as a traditional cooling tea for fevers, though use should be short-term and PA-aware.

Infusion (tea)[6, 10]

Dried flower heads steeped in hot water, the classic way of taking chamomile for digestive complaints, mild anxiety and sleep support.

Essential oil[1]

Steam-distilled from the flower heads; a concentrated source of alpha-bisabolol and chamazulene, used mainly in topical and aromatherapy preparations.

Topical cream/compress[12]

Concentrated extract or infused oil applied to skin, or as a compress - a randomised controlled trial found a topical chamomile oil preparation effective for knee osteoarthritis pain.

Dosage

Whole-herb preparations[6, 14]

A phase-two randomised placebo-controlled trial in moderate persistent asthma used Borago officinalis extract at 5 mL three times daily for one month. Because of pyrrolizidine alkaloid content, whole-herb (leaf/flower) preparations should only be used short-term and from PA-controlled sources; avoid in pregnancy, breastfeeding and liver disease. Educational reference only, not a prescription.

Infusion (tea)[15, 16, 17, 18, 19]

Traditional guidance and Duke (2002) suggest about 3 g of dried flower heads per cup of water, taken up to three times daily. Educational reference only, not a prescription.

References

REF-0749, REF-0750, REF-0751, REF-1950, REF-1951, REF-1952, REF-1953, REF-1954, REF-1955, REF-1956, REF-1957, REF-1958, REF-1959
REF-1153, REF-1154, REF-1155, REF-1156, REF-1157, REF-1158, REF-1159, REF-1160, REF-1161, REF-1162, REF-2348, REF-2349, REF-2350, REF-2351

Lookalikes Review

Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-06
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Dangerous Lookalikes

Safety note[19, 20]Fatal
Dangerous Plant: digitalis-purpurea
Confused Part: Pre-flowering rosette leaves gathered for cooking (salads, savoury pies, pasta fillings).
Confusion Context: Foxglove's soft, wrinkled first-year leaves closely resemble borage leaves gathered for food, and the mix-up is repeatedly documented — including people who developed high digitoxin levels and heart block after eating a few 'borage' leaves, one batch bought from a nursery mislabelled as borage. Foxglove leaves contain cardiac glycosides and can be fatal.
Distinguishing Features: Borage leaves bear coarse, stiff, bristly hairs that feel rough or prickly; foxglove leaves are softly downy and velvety., Crushed borage foliage smells clearly of cucumber; foxglove foliage has no cucumber smell., In flower they are unmistakable: borage has bright blue five-pointed star flowers with a black central cone; foxglove has tall one-sided spikes of pendulous tubular thimble flowers. Do not identify from leaves alone if you can wait for flowers.
Key Test: Rub and crush a leaf: borage feels coarse and bristly and smells of cucumber; a soft, velvety leaf with no cucumber smell should be treated as foxglove — do not eat it.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-06

Not documented

Drug Class Interactions

Not documented

Safety note[21]Caution
Drug Class: anticoagulants-antiplatelets
Mechanism: Chamomile contains natural coumarin constituents and has been linked in a case report to increased bleeding when taken with warfarin, so caution is advised when combining it with anticoagulant or antiplatelet drugs.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Safety note[22, 23, 24]Caution
Drug Class: sedatives-cns-depressants
Mechanism: Chamomile has calming, sedative effects (a randomised controlled trial found it reduces generalised-anxiety symptoms); taken with sedatives, sleeping tablets or other central-nervous-system depressants (including alcohol) it may add to drowsiness and slowed reactions.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Safety note[25]Caution
Drug Class: antidiabetics
Mechanism: Chamomile improved blood-sugar control (lower HbA1c and insulin resistance) in a trial in type 2 diabetes; combined with diabetes medicines it may add to blood-sugar lowering, so monitor blood sugar.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Pairings

Not documented

Chamomile and valerian are both traditional mild sedatives for restlessness and poor sleep; taken together they may enhance calming and sleep effects but also add to drowsiness.[23]

Partner Id: valeriana-officinalis
Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Chamomile and lemon balm are both gentle calming herbs commonly combined for stress and sleep; used together their mild sedative effects may add up.[23]

Partner Id: melissa-officinalis
Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Chamomile and passionflower are both gentle calming, sleep-supporting herbs traditionally combined; used together they may reinforce each other's soothing, sleep-promoting effect.[22, 23]

Partner Id: passiflora-incarnata
Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

References & Sources

  1. Slama, M., Slougui, N., Benaissa, A., Nekkaa, A. et al (2024) 'Borago officinalis L.: A Review on Extraction, Phytochemical, and Pharmacological Activities', Chemistry & Biodiversity, 21(5), pp. e202301822. doi:10.1002/cbdv.202301822 Traditional / reference
    https://doi.org/10.1002/cbdv.202301822
  2. Michalak, M., Zagórska-Dziok, M., Klimek-Szczykutowicz, M. and Szopa, A (2023) 'Phenolic Profile and Comparison of the Antioxidant, Anti-Ageing, Anti-Inflammatory, and Protective Activities of Borago officinalis Extracts on Skin Cells', Molecules, 28(2), pp. 868. doi:10.3390/molecules28020868 Preclinical
    https://doi.org/10.3390/molecules28020868
  3. Ghasemian, M., Owlia, S. and Owlia, M.B (2016) 'Review of Anti-Inflammatory Herbal Medicines', Advances in Pharmacological Sciences, 2016, pp. 9130979. doi:10.1155/2016/9130979 Traditional / reference
    https://doi.org/10.1155/2016/9130979
  4. Di Cerbo, A., Carnevale, G., Avallone, R., Zavatti, M. and Corsi, L (2020) 'Protective Effects of Borago officinalis (Borago) on Cold Restraint Stress-Induced Gastric Ulcers in Rats: A Pilot Study', Frontiers in Veterinary Science, 7, pp. 427. doi:10.3389/fvets.2020.00427 Preclinical
    https://doi.org/10.3389/fvets.2020.00427
  5. Seo, S.A., Park, B., Hwang, E., Park, S. and Yi, T (2018) 'Borago officinalis L. attenuates UVB-induced skin photodamage via regulation of AP-1 and Nrf2/ARE pathway in normal human dermal fibroblasts and promotion of collagen synthesis in hairless mice', Experimental Gerontology, 107, pp. 178-186. doi:10.1016/j.exger.2018.02.017 Preclinical
    https://doi.org/10.1016/j.exger.2018.02.017
  6. Mirsadraee, M., Khashkhashi Moghaddam, S., Saeedi, P. and Ghaffari, S (2016) 'Effect of Borago Officinalis Extract on Moderate Persistent Asthma: A Phase two Randomized, Double Blind, Placebo-Controlled Clinical Trial', Tanaffos, 15(3), pp. 168-174. doi:10.1183/13993003.congress-2016.pa4116 Randomized trial
    https://doi.org/10.1183/13993003.congress-2016.pa4116
  7. Lozano-Baena, M., Tasset, I., Munoz-Serrano, A., Alonso-Moraga, A. and de Haro-Bailon, A (2016) 'Cancer Prevention and Health Benefices of Traditionally Consumed Borago officinalis Plants', Nutrients, 8(1), pp. 48. doi:10.3390/nu8010048 Preclinical
    https://doi.org/10.3390/nu8010048
  8. Rodriguez-Magana, M.P., Cordero-Perez, P., Rivas-Morales, C., Oranday-Cardenas, M.A., Moreno-Pena, D.P., Garcia-Hernandez, D.G. and Leos-Rivas, C (2019) 'Hypoglycemic Activity of Tilia americana, Borago officinalis, Chenopodium nuttalliae, and Piper sanctum on Wistar Rats', Journal of Diabetes Research, 2019, pp. 7836820. doi:10.1155/2019/7836820 Preclinical
    https://doi.org/10.1155/2019/7836820
  9. Navarro-Herrera, D., Aranaz, P., Eder-Azanza, L., Zabala, M., Romo-Hualde, A., Hurtado, C., Calavia, D., Lopez-Yoldi, M., Martinez, J.A., Gonzalez-Navarro, C.J. and Vizmanos, J.L (2018) 'Borago officinalis seed oil (BSO), a natural source of omega-6 fatty acids, attenuates fat accumulation by activating peroxisomal beta-oxidation both in C. elegans and in diet-induced obese rats', Food & Function, 9(8), pp. 4340-4351. doi:10.1039/c8fo00423d Preclinical
    https://doi.org/10.1039/c8fo00423d
  10. Moliner, C., Casedas, G., Barros, L., Finimundy, T.C., Gomez-Rincon, C. and Lopez, V (2022) 'Neuroprotective Profile of Edible Flowers of Borage (Borago officinalis L.) in Two Different Models: Caenorhabditis elegans and Neuro-2a Cells', Antioxidants, 11(7), pp. 1244. doi:10.3390/antiox11071244 Preclinical
    https://doi.org/10.3390/antiox11071244
  11. Samy, M.N., Hamed, A.N.E., Sugimoto, S., Otsuka, H., Kamel, M.S. and Matsunami, K (2015) 'Officinalioside, a new lignan glucoside from Borago officinalis L', Natural Product Research, 30(8), pp. 967-972. doi:10.1080/14786419.2015.1088540 Preclinical
    https://doi.org/10.1080/14786419.2015.1088540
  12. Yue, Y., Jin, F. and Yue, X (2021) 'The effect of Borago officinalis on the signaling pathway of the NLRP3 inflammasome complex, TLR4 and some inflammatory cytokines in type II diabetic patients with acute respiratory distress syndrome', Cellular and Molecular Biology, 67(3), pp. 178-183. doi:10.14715/cmb/2021.67.3.28 Clinical study
    https://doi.org/10.14715/cmb/2021.67.3.28
  13. Fernandes, L., Pereira, J.A., Saraiva, J.A., Ramalhosa, E. and Casal, S (2019) 'Phytochemical characterization of Borago officinalis L. and Centaurea cyanus L. during flower development', Food Research International, 123, pp. 771-778. doi:10.1016/j.foodres.2019.05.014 Preclinical
    https://doi.org/10.1016/j.foodres.2019.05.014
  14. European Medicines Agency (HMPC) (2021) 'Public statement on the use of herbal medicinal products containing toxic, unsaturated pyrrolizidine alkaloids (PAs), including recommendations regarding contamination of herbal medicinal products with PAs, Revision 1'. Available at: https://www.ema.europa.eu/en/documents/public-statement/public-statement-use-herbal-medicinal-products-containing-toxic-unsaturated-pyrrolizidine-alkaloids-pas-including-recommendations-regarding-contamination-herbal-medicinal-products-pyrrolizidine_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/public-statement/public-statement-use-herbal-medicinal-products-containing-toxic-unsaturated-pyrrolizidine-alkaloids-pas-including-recommendations-regarding-contamination-herbal-medicinal-products-pyrrolizidine_en.pdf
  15. Kapoor, R. and Huang, Y.S (2006) 'Gamma linolenic acid: an antiinflammatory omega-6 fatty acid', 7(6), pp. 531--534. doi:10.2174/138920106779116874 Traditional / reference
    https://doi.org/10.2174/138920106779116874
  16. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
    https://powo.science.kew.org
  17. World Health Organization (2002) 'WHO Monographs on Selected Medicinal Plants'. Traditional / reference
    https://scholar.google.com/scholar?q=WHO%20Monographs%20on%20Selected%20Medicinal%20Plants
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  6. Dai, Y.L., Li, Y., Wang, Q., Niu, F.J. and others (2022) 'Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies', Molecules, 28(1), pp. 133. doi:10.3390/molecules28010133 Meta-analysis / review
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  8. Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K. and others (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
    https://doi.org/10.1097/JCP.0b013e3181ac935c
  9. Park, S.H., Kim, D.S., Oh, J., Geum, J.H. and others (2021) 'Matricaria chamomilla (Chamomile) Ameliorates Muscle Atrophy in Mice by Targeting Protein Catalytic Pathways, Myogenesis, and Mitochondrial Dysfunction', The American Journal of Chinese Medicine, 49(6), pp. 1493-1514. doi:10.1142/S0192415X21500701 Preclinical
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  11. Amsterdam, J.D., Shults, J., Soeller, I., Mao, J.J., Rockwell, K. and Newberg, A.B (2012) 'Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study', Alternative Therapies in Health and Medicine, 18(5), pp. 44-49. Randomized trial
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  12. Shoara, R., Hashempur, M.H., Ashraf, A., Salehi, A., Dehshahri, S. and Habibagahi, Z (2015) 'Efficacy and safety of topical Matricaria chamomilla L. (chamomile) oil for knee osteoarthritis: a randomized controlled clinical trial', Complementary Therapies in Clinical Practice, 21(3), pp. 181-187. doi:10.1016/j.ctcp.2015.06.003 Randomized trial
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  13. Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2016) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
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  14. Niazi, A. and Moradi, M (2021) 'The effect of chamomile on pain and menstrual bleeding in primary dysmenorrhea: a systematic review', International Journal of Community Based Nursing and Midwifery, 9(3), pp. 174-186. doi:10.30476/ijcbnm.2021.87219.1417 Meta-analysis / review
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  22. Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
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  24. Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K., Mao, J.J. and Shults, J (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
    https://doi.org/10.1097/JCP.0b013e3181ac935c
  25. Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2015) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.