Plant Comparison

Lady’s-mantle vs White clover

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ALady’s-mantleAlchemilla vulgarisRosaceaeFull monograph →
Plant BWhite cloverTrifolium repensFabaceaeFull monograph →

At a glance

Lady’s-mantle and White clover: they share 7 indicated uses (arthritis / joint pain, bruising, cancer (anticancer research), …); 4 pharmacological actions in common.

Lady’s-mantleWhite clover
Constituents13
Pharmacological actions411
Indicated uses715
Safety notes22
Cited sources1833
Indicated uses
Only Lady’s-mantle
none
Shared (7)
Arthritis / joint painBruisingCancer (anticancer research)Inflammation (general)Menstrual crampsSkin irritationWounds
Only White clover
Cold & fluImmune supportMuscle spasmKidney supportLiver supportBlood sugar / diabetes supportInfection (general)Cognitive function
Pharmacological actions
Only Lady’s-mantle
none
Shared (4)
Anti-inflammatoryAnticancer (preclinical)AntioxidantVulnerary (wound healing)
Only White clover
AntispasmodicImmunomodulator / immune supportNephroprotective (kidney support)Hepatoprotective (liver support)AntimicrobialAntidiabetic (blood-sugar lowering)Neuroprotective / cognition support

Evidence face-off — shared uses

ConditionLady’s-mantleWhite cloverVerdict
Arthritis / joint pain2/101/10Comparable evidence
Bruising1/101/10Comparable evidence
Cancer (anticancer research)2/102/10Comparable evidence
Inflammation (general)2/102/10Comparable evidence
Menstrual cramps1/101/10Comparable evidence
Skin irritation2/101/10Comparable evidence
Wounds1/107/10Stronger for White clover

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Phenolic compounds and tannins[5, 8]

Lady's mantle is rich in ellagitannins and other tannins (the basis of its astringency) together with phenolic acids (gallic and caffeic acids) and flavonoids such as quercetin and catechin, which underlie its antioxidant activity.

Phenolic compoundsPhenolic acidsTanninsCaffeic acidFlavonoidsQuercetinCatechinsGallic acid
Isoflavones[32]

Phytoestrogenic isoflavones, present at lower levels than in red clover.

Flavonoids
Cyanogenic glycosides (trace)[30]

Present in small amounts; not significant in normal food or tea use.

Glycosides
Phenolic acids and flavonoids[32]

Contribute to antioxidant activity.

Phenolic acidsFlavonoids

Pharmacological Actions

Anti-inflammatory[4, 6, 7, 9, 14, 15, 16]
Anticancer (preclinical)[1, 5, 8, 17]

Alchemilla vulgaris extracts (aerial parts and root) show antioxidant, genoprotective and antitumor activity against multiple human cancer cell lines (preclinical).

Antioxidant[3, 5, 6, 8, 10, 13, 14, 15, 16]
Vulnerary (wound healing)[14, 15, 16]
Anti-inflammatory[1, 2, 5, 6, 22, 28, 30, 31, 32]
Antioxidant[1, 2, 4, 5, 7, 8, 9, 10, 14, 16, 17, 20, 21, 23, 24, 25, 28, 30, 31, 32]
Antispasmodic[30, 31, 32]

Antispasmodic (cramp easing)

Immunomodulator / immune support[2, 30, 31, 32]
Vulnerary (wound healing)[1, 7, 13, 30, 31, 32]
Nephroprotective (kidney support)[4]
Anticancer (preclinical)[3, 10]
Hepatoprotective (liver support)[9]
Antimicrobial[12, 18, 22, 26, 28]
Antidiabetic (blood-sugar lowering)[10, 20]
Neuroprotective / cognition support[22, 23]

Traditional & Indicated Uses

Arthritis / joint pain[6, 14, 15, 16]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Arthritis / joint pain
Bruising[14, 15, 16]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Cancer (anticancer research)[1, 5, 8, 17]Traditional · 2/10

Alchemilla vulgaris extracts suppress the growth of MCF-7, A375, A549, HCT116 (aerial parts) and PC-3, MCF-7, Caco-2 (root) cancer cells via caspase-dependent apoptosis and autophagy, while protecting normal cells (preclinical).

Evidence: 2
Label: Cancer (anticancer research)
Inflammation (general)[6, 14, 15, 16]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Inflammation (general)
Menstrual cramps[14, 15, 16]Traditional · 1/10
Evidence: 1
Label: Menstrual cramps
Skin irritation[6, 14, 15, 16]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Skin irritation
Wounds[14, 15, 16]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Wounds
Arthritis / joint pain[30, 31, 32]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bruising[30, 31, 32]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Cancer (anticancer research)[3, 10]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Cold & flu[30, 31, 32]Traditional · 1/10

inferred from immunomodulator action

Evidence: 1
Label: Cold & flu
Immune support[30, 31, 32]Traditional · 1/10
Evidence: 1
Label: Immune support
Inflammation (general)[6, 30, 31, 32]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Inflammation (general)
Menstrual cramps[30, 31, 32]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Menstrual cramps
Muscle spasm[30, 31, 32]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Muscle spasm
Skin irritation[30, 31, 32]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[1, 7, 13, 30, 31, 32]Good · 7/10

inferred from vulnerary action

Evidence: 7
Label: Wounds
Kidney support[4]Traditional · 2/10
Evidence: 2
Label: Kidney support
Liver support[9]Traditional · 2/10
Evidence: 2
Label: Liver support
Blood sugar / diabetes support[10, 20]Traditional · 2/10
Evidence: 2
Label: Blood sugar / diabetes support
Infection (general)[12, 18, 22, 26]Traditional · 2/10

inferred from antimicrobial action

Evidence: 2
Label: Infection (general)
Cognitive function[22, 23]Traditional · 2/10
Evidence: 2
Label: Cognitive function

Safety, Cautions & Contraindications

Safety note[14, 15, 16]Caution

Generally considered very safe. One of the gentlest astringent herbs in European herbalism. No significant drug interactions. Tannin content means very high doses should be avoided in sensitive stomachs. Not significantly contraindicated in pregnancy at normal herbal tea doses, but medicinal doses should be used cautiously.

Safety note[14, 15, 16, 18]Info

Duke (2002) rates lady's mantle as ++ and notes astringent, angioprotective, anti-inflammatory, and vulnerary activities at the experimental level (score 1). The plant is rich in tannins and is traditionally used for diarrhea, wound healing, and as a mild gynecological tonic. Duke notes its anti-inflammatory and antioxidant properties as experimentally supported. No significant safety concerns are noted at usual herbal doses; the plant is generally well-tolerated (Duke, 2002).

Safety note[30, 31, 32]Caution

Generally very safe as a food and in moderate herbal use. Cyanogenic glucosides present in very small amounts — not significant in normal food or tea use. Isoflavones are phytoestrogens (as in red clover) — same precautions apply in hormone-sensitive conditions. Well tolerated by most people.

Safety note[30, 31, 32, 33]Info

Duke (2002) does not include a dedicated entry for white clover (Trifolium repens) in the Handbook of Medicinal Herbs, Second Edition.

External Ids

Gbif: 7890713
Wikidata: Q160189
Gbif: 5358748
Wikidata: Q148675

Botanical Description

Low, clump-forming perennial herb with distinctive rounded, softly hairy leaves divided into 7-11 shallow, scalloped, toothed lobes, fanning out like a cloak (giving the genus name Alchemilla, 'little alchemist', after the dew drops that collect in the leaf centre, once prized by alchemists). Tiny, petal-less, yellow-green flowers are borne in loose, branching clusters above the foliage.[14]

Height: 10-40 cm
Habit: Low, clump-forming perennial herb
Leaves: Rounded, softly hairy, palmately lobed into 7-11 shallow scalloped, toothed lobes
Flowers: Tiny, petal-less, yellow-green flowers in loose branching clusters
Stem: Short, softly hairy flowering stems rising above the leaf clump
Root: Short, stout rootstock
Fruit: Small dry achene
Flowering Period: May-September

Low, creeping perennial herb rooting at the nodes, with trifoliate leaves, each leaflet oval and often marked with a pale chevron. Rounded white (sometimes pink-tinged) flower heads are borne on long stalks above the foliage.[30]

Height: 5-15 cm (creeping, flower stalks slightly taller)
Habit: Low, creeping, mat-forming perennial herb
Leaves: Trifoliate, each leaflet oval, often marked with a pale chevron
Flowers: Rounded white (sometimes pink-tinged) heads of small pea-like flowers on long stalks
Stem: Creeping, rooting at the nodes
Root: Fibrous roots with nitrogen-fixing nodules
Fruit: Small pod containing 3-4 seeds
Flowering Period: May-October

Habitat

Grows in damp meadows, pastures, mountain grassland, streamsides and open woodland, typically on moist, nutrient-rich soils; native to Europe and parts of temperate Asia, favouring cooler upland and northern regions.[14]

Grows in lawns, pastures, meadows and grassy waste ground; native to Europe and western Asia and now naturalised worldwide, including as a common lawn and forage plant.[30]

Harvesting

The leaves and flowering tops are gathered in summer while the plant is in flower, and dried in a warm, shaded, airy place.[14]

Parts: Flower, Leaf
Season: Summer flowering period

Flowering heads and leaves are picked through the flowering season and dried in a warm, shaded, airy place.[30]

Parts: Flower, Leaf
Season: May-October

Traditional Uses

Lady's mantle has long been used in European herbal medicine as a gentle astringent for menstrual complaints and as a mild gynaecological tonic, and topically for minor wounds and skin inflammation, reflecting its tannin-rich astringent character.[15]

White clover has a folk tradition, similar to but lighter than its relative red clover, as an anti-inflammatory and wound-healing remedy and mild expectorant, and modern research on its isoflavones and phenolics has additionally investigated antioxidant, kidney-protective and liver-protective activity.[30, 31, 32]

Preparations

Infusion[15]

Dried leaf and flowering tops infused in hot water, traditionally taken for menstrual complaints and mild digestive upset.

Infusion (flower/leaf)[30]

Dried flower and leaf infused in hot water as a traditional mild tonic and expectorant tea.

References

REF-0688, REF-0689, REF-2226, REF-2227, REF-0686, REF-0685, REF-2228, REF-0687, REF-2229, REF-2230, REF-2231, REF-2232, REF-2233
REF-1323, REF-1324, REF-1325, REF-1326, REF-1327, REF-2366, REF-2367, REF-2368, REF-2369, REF-2901, REF-2902, REF-2903, REF-2904, REF-2905, REF-2906, REF-2907, REF-2908, REF-2909, REF-2910, REF-2935, REF-2936, REF-2937, REF-2938, REF-2939, REF-2940, REF-2941, REF-2942, REF-2943, REF-2944

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Jelaca, S., Jovanovic, I., Bovan, D., Jovanovic, M.Z., Jurisevic, M.M., Dundjerovic, D. and others (2024) 'Dual Role of Alchemilla vulgaris L. Extract in Breast Cancer Regression: Reestablishment of Effective Immune Response', Pharmaceuticals, 17(3). doi:10.3390/ph17030286 Preclinical
    https://doi.org/10.3390/ph17030286
  2. Jelaca, S., Jovanovic, I., Bovan, D., Pavlovic, S., Gajovic, N., Dundjerovic, D. and others (2024) 'Antimelanoma Effects of Alchemilla vulgaris: A Comprehensive In Vitro and In Vivo Study', Diseases, 12(6). doi:10.3390/diseases12060125 Preclinical
    https://doi.org/10.3390/diseases12060125
  3. Kanak, S., Krzeminska, B., Celinski, R., Bakalczuk, M. and Dos Santos Szewczyk, K (2022) 'Phenolic composition and antioxidant activity of Alchemilla species', Plants, 11(20), pp. 2709. doi:10.3390/plants11202709 Meta-analysis / review
    https://doi.org/10.3390/plants11202709
  4. Jakimiuk, K. and Tomczyk, M (2023) 'A review of the traditional uses, phytochemistry, pharmacology, and clinical evidence for the use of the genus Alchemilla (Rosaceae)', Journal of Ethnopharmacology, 320, pp. 117439. doi:10.1016/j.jep.2023.117439 Meta-analysis / review
    https://doi.org/10.1016/j.jep.2023.117439
  5. Jelaca, S., Dajic-Stevanovic, Z., Vukovic, N., Kolasinac, S., Trendafilova, A., Nedialkov, P. and others (2022) 'Beyond Traditional Use of Alchemilla vulgaris: Genoprotective and Antitumor Activity In Vitro', Molecules, 27(23). doi:10.3390/molecules27238113 Traditional / reference
    https://doi.org/10.3390/molecules27238113
  6. Anajirih, N., Abdeen, A., Taher, E.S., Abdelkader, A., Abd-Ellatieff, H.A., Gewaily, M.S. and others (2024) 'Alchemilla vulgaris modulates isoproterenol-induced cardiotoxicity: interplay of oxidative stress, inflammation, autophagy, and apoptosis', Frontiers in Pharmacology. doi:10.3389/fphar.2024.1394557 Preclinical
    https://doi.org/10.3389/fphar.2024.1394557
  7. Karaoglan, E.S., Bayir, Y., Albayrak, A., Toktay, E., Ozgen, U., Kazaz, C., Kahramanlar, A. and Cadirci, E (2020) 'Isolation of major compounds and gastroprotective activity of Alchemilla on indomethacin induced gastric ulcers in rats', Eurasian Journal of Medicine, 52(3), pp. 249-253. doi:10.5152/eurasianjmed.2020.19243 Preclinical
    https://doi.org/10.5152/eurasianjmed.2020.19243
  8. Vlaisavljevic, S., Jelaca, S., Zengin, G., Mimica-Dukic, N., Berezni, S., Miljic, M. and Dajic Stevanovic, Z (2019) 'Alchemilla vulgaris agg. (Lady's mantle) from central Balkan: antioxidant, anticancer and enzyme inhibition properties', RSC Advances, 9(64), pp. 37474--37483. doi:10.1039/c9ra08231j Preclinical
    https://doi.org/10.1039/c9ra08231j
  9. Kupeli Akkol, E., Demirel, M.A., Bahadir Acikara, O., Suntar, I., Ergene, B., Ilhan, M., Ozbilgin, S., Saltan, G., Keles, H. and Tekin, M (2015) 'Phytochemical analyses and effects of Alchemilla mollis (Buser) Rothm. and Alchemilla persica Rothm. in rat endometriosis model', Archives of Gynecology and Obstetrics, 292(3), pp. 619-628. doi:10.1007/s00404-015-3665-6 Preclinical
    https://doi.org/10.1007/s00404-015-3665-6
  10. Dos Santos Szewczyk, K., Pietrzak, W., Klimek, K., Grzywa-Celinska, A., Celinski, R. and Gogacz, M (2022) 'LC-ESI-MS/MS identification of biologically active phenolics in different extracts of Alchemilla acutiloba Opiz', Molecules, 27(3), pp. 621. doi:10.3390/molecules27030621 Preclinical
    https://doi.org/10.3390/molecules27030621
  11. Ozbek, H., Acikara, O.B., Keskin, I., Kirmizi, N.I., Ozbilgin, S., Oz, B.E., Kurtul, E., Ozrenk, B.C., Tekin, M. and Saltan, G (2016) 'Evaluation of hepatoprotective and antidiabetic activity of Alchemilla mollis', Biomedicine & Pharmacotherapy, 86, pp. 172-176. doi:10.1016/j.biopha.2016.12.005 Preclinical
    https://doi.org/10.1016/j.biopha.2016.12.005
  12. Krivokuca, M., Niketic, M., Milenkovic, M., Golic, N., Masia, C., Scaltrito, M.M., Sisto, F. and Kundakovic, T (2015) 'Anti-Helicobacter pylori activity of four Alchemilla species (Rosaceae)', Natural Product Communications, 10(8), pp. 1369-1371. doi:10.1177/1934578x1501000814 Preclinical
    https://doi.org/10.1177/1934578x1501000814
  13. Duckstein, S.M., Lotter, E.M., Meyer, U., Lindequist, U. and Stintzing, F.C (2013) 'Phenolic constituents from Alchemilla vulgaris L. and Alchemilla mollis (Buser) Rothm. at different dates of harvest', Zeitschrift fur Naturforschung C, 68(1-2), pp. 529-540. doi:10.1515/znc-2012-11-1201 Preclinical
    https://doi.org/10.1515/znc-2012-11-1201
  14. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
    https://powo.science.kew.org
  15. Hoffmann, D (2003) 'Medical Herbalism: The Science and Practice of Herbal Medicine'. Traditional / reference
    https://scholar.google.com/scholar?q=Medical%20Herbalism%3A%20The%20Science%20and%20Practice%20of%20Herbal%20Medicine
  16. Pauli, A. and Schilcher, H (2012) 'In vitro antimicrobial activities of essential oils monographed in the European Pharmacopoeia 6th edition'. Traditional / reference
    https://scholar.google.com/scholar?q=In%20vitro%20antimicrobial%20activities%20of%20essential%20oils%20monographed%20in%20the%20European%20Pharmacopoeia%206th%20edition
  17. Ibrahim, O.H.M. and Abo-Elyousr, K.A.M. and Asiry, K.A. and Alhakamy, N.A. and Mousa, M.A.A (2022) 'Phytochemical Characterization, Antimicrobial Activity and In Vitro Antiproliferative Potential of Alchemilla vulgaris Auct Root Extract against Prostate (PC-3), Breast (MCF-7) and Colorectal Adenocarcinoma (Caco-2) Cancer Cell Lines', Plants, 11(16), pp. 2140. doi:10.3390/plants11162140 Preclinical
    https://doi.org/10.3390/plants11162140
  18. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  1. Ngangom, L., Venugopal, D. and Pandey, N (2024) 'Investigation of Trifolium repens L. from the Indian Himalayan region as a phyto-therapeutic agent', Natural Product Research, 38(24), pp. 4468-4478. doi:10.1080/14786419.2023.2299319 Meta-analysis / review
    https://doi.org/10.1080/14786419.2023.2299319
  2. Ahmad, S. and Zeb, A (2020) 'Phytochemical profile and pharmacological properties of Trifolium repens', Journal of Basic and Clinical Physiology and Pharmacology, 32(3), pp. 20200015. doi:10.1515/jbcpp-2020-0015 Meta-analysis / review
    https://doi.org/10.1515/jbcpp-2020-0015
  3. Sarno, F., Pepe, G., Termolino, P., Carafa, V. and others (2020) 'Trifolium repens Blocks Proliferation in Chronic Myelogenous Leukemia via the BCR-ABL/STAT5 Pathway', Cells, 9(2), pp. 379. doi:10.3390/cells9020379 Preclinical
    https://doi.org/10.3390/cells9020379
  4. Ahmad, S. and Zeb, A (2020) 'Nephroprotective property of Trifolium repens leaf extract against paracetamol-induced kidney damage in mice', 3 Biotech, 10(12), pp. 541. doi:10.1007/s13205-020-02539-0 Preclinical
    https://doi.org/10.1007/s13205-020-02539-0
  5. Kolodziejczyk-Czepas, J (2012) 'Trifolium species-derived substances and extracts--biological activity and prospects for medicinal applications', Journal of Ethnopharmacology, 143(1), pp. 14-23. doi:10.1016/j.jep.2012.06.048 Meta-analysis / review
    https://doi.org/10.1016/j.jep.2012.06.048
  6. Chen, Y.H., Chen, P., Wang, Y., Yang, C.H., Wu, X., Wu, C.J., Luo, L., Wang, Q., Niu, C. and Yao, J.Y (2019) 'Structural characterization and anti-inflammatory activity evaluation of chemical constituents in the extract of Trifolium repens L', Journal of Food Biochemistry, 43(9), pp. e12981. doi:10.1111/jfbc.12981 Preclinical
    https://doi.org/10.1111/jfbc.12981
  7. Habibi Zadeh, S.K., Farahpour, M.R. and Kar, H.H (2020) 'The effect of topical administration of an ointment prepared from Trifolium repens hydroethanolic extract on the acceleration of excisional cutaneous wound healing', Wounds, 32(9), pp. 253-261. doi:10.25270/wnds/2020.253261 Preclinical
    https://doi.org/10.25270/wnds/2020.253261
  8. Kicel, A. and Wolbis, M (2012) 'Study on the phenolic constituents of the flowers and leaves of Trifolium repens L', Natural Product Research, 26(21), pp. 2050-2054. doi:10.1080/14786419.2011.637217 Preclinical
    https://doi.org/10.1080/14786419.2011.637217
  9. Ahmad, S. and Zeb, A (2019) 'Effects of phenolic compounds from aqueous extract of Trifolium repens against acetaminophen-induced hepatotoxicity in mice', Journal of Food Biochemistry, 43(9), pp. e12963. doi:10.1111/jfbc.12963 Preclinical
    https://doi.org/10.1111/jfbc.12963
  10. Borczak, B. and Szewczyk, A. and Domagała, D. and Kapusta-Duch, J. and Leszczyńska, T. and Kotuła, M. and Grulova, D (2024) 'Potential Antidiabetic, Antioxidative and Antiproliferative Properties of Functional Wheat Flour Muffins Enriched with White Clover Flowers (Trifolium repens L.)', Int J Mol Sci, 25(18). doi:10.3390/ijms25189909 Preclinical
    https://doi.org/10.3390/ijms25189909
  11. Rawat, P. and Kumar, B. and Misra, A. and Singh, S.P. and Singh, S.P. and Srivastava, S (2025) 'Effect of hydrolysed Trifolium repens L. extract on menopause-induced obesity and depressive symptoms: an in vitro and in vivo approach', Nat Prod Res, pp. 1-8. doi:10.1080/14786419.2025.2560636 Preclinical
    https://doi.org/10.1080/14786419.2025.2560636
  12. Parić, A. and Mesic, A. and Mahmutović-Dizdarević, I. and Jerković-Mujkić, A. and Žujo, B. and Bašić, N. and Pustahija, F (2024) 'Bioactive potential of Trifolium repens L. essential oil', J Environ Sci Health B, 59(9), pp. 584-594. doi:10.1080/03601234.2024.2396730 Preclinical
    https://doi.org/10.1080/03601234.2024.2396730
  13. Renda, G. and Yalçın, F.N. and Nemutlu, E. and Akkol, E.K. and Süntar, I. and Keleş, H. and Ina, H. and Çalış, I. and Ersöz, T (2013) 'Comparative assessment of dermal wound healing potentials of various Trifolium L. extracts and determination of their isoflavone contents as potential active ingredients', J Ethnopharmacol, 148(2), pp. 423-32. doi:10.1016/j.jep.2013.04.031 Preclinical
    https://doi.org/10.1016/j.jep.2013.04.031
  14. Ahmed, I.A.M. and Matthäus, B. and Özcan, M.M. and Juhaimi, F.A. and Ghafoor, K. and Babiker, E.E. and Osman, M.A. and Alqah, H.A.S (2020) 'Determination of Bioactive Lipid and Antioxidant Activity of Onobrychis, Pimpinella, Trifolium, and Phleum spp. Seed and Oils', J Oleo Sci, 69(11), pp. 1367-1371. doi:10.5650/jos.ess20153 Preclinical
    https://doi.org/10.5650/jos.ess20153
  15. Harlow, B.E. and Flythe, M.D. and Goodman, J.P. and Ji, H. and Aiken, G.E (2022) 'Isoflavone Containing Legumes Mitigate Ergot Alkaloid-Induced Vasoconstriction in Goats (Capra hircus)', Animals (Basel), 12(6). doi:10.3390/ani12060750 Preclinical
    https://doi.org/10.3390/ani12060750
  16. Shang, H. and Li, R. and Wu, H. and Sun, Z (2019) 'Polysaccharides from Trifolium repens L. extracted by different methods and extraction condition optimization', Sci Rep, 9(1), pp. 6353. doi:10.1038/s41598-019-42877-5 Preclinical
    https://doi.org/10.1038/s41598-019-42877-5
  17. Prati, S. and Baravelli, V. and Fabbri, D. and Schwarzinger, C. and Brandolini, V. and Maietti, A. and Tedeschi, P. and Benvenuti, S. and Macchia, M. and Marotti, I. and Bonetti, A. and Catizone, P. and Dinelli, G (2007) 'Composition and content of seed flavonoids in forage and grain legume crops', J Sep Sci, 30(4), pp. 491-501. doi:10.1002/jssc.200600383 Preclinical
    https://doi.org/10.1002/jssc.200600383
  18. Woolsey, I.D. and Zeller, W.E. and Blomstrand, B.M. and Øines, Ø. and Enemark, H.L (2022) 'Effects of selected condensed tannins on Cryptosporidium parvum growth and proliferation in HCT-8 cell cultures', Exp Parasitol, 241, pp. 108353. doi:10.1016/j.exppara.2022.108353 Preclinical
    https://doi.org/10.1016/j.exppara.2022.108353
  19. Hou, K. and Xue, Q. and Shi, L. and Liu, S. and Zhong, X. and Liu, Y. and Wang, C (2026) 'Identification of Trifolium repens as a New Source of Glycyrrhetinic Acid: Pathway Elucidation and Heterologous Reconstruction in Yeast', J Agric Food Chem, 74(19), pp. 15182-15194. doi:10.1021/acs.jafc.6c02001 Preclinical
    https://doi.org/10.1021/acs.jafc.6c02001
  20. Tundis, R. and Marrelli, M. and Conforti, F. and Tenuta, M.C. and Bonesi, M. and Menichini, F. and Loizzo, M.R (2015) 'Trifolium pratense and T. repens (Leguminosae): Edible Flower Extracts as Functional Ingredients', Foods, 4(3), pp. 338-348. doi:10.3390/foods4030338 Preclinical
    https://doi.org/10.3390/foods4030338
  21. Başar, Y. and Yıldız, İ. and HOSAFLIOĞLU, İ. and Azeroual, A. and Erenler, R (2026) 'The Phytochemical Content and DPPH Activity of Trifolium repens L. Methanol Extract, and In Silico Studies', Adıyaman üniversitesi fen bilimleri dergisi, 16(1), pp. 61-76. doi:10.37094/adyujsci.1813336 Preclinical
    https://doi.org/10.37094/adyujsci.1813336
  22. Ayoubi, S.A. and Abdelwahab, I. and Ela, M.A. and Lakany, A.E. and Raafat, K (2026) 'Advanced Hybrid-Green Ultrasound–Infrared–Microwave Trifolium repens Essential oil Isolation with Multi-Target Ethnomedicine Bioactivity against Neuropathy, Inflammation and Multidrug-Resistant Infection', Journal of Food and Drug Analysis, 34(2). doi:10.38212/2224-6614.3595 Preclinical
    https://doi.org/10.38212/2224-6614.3595
  23. Ahmad, S. and Zeb, A. and Ayaz, M. and Murkovic, M (2019) 'Characterization of phenolic compounds using UPLC–HRMS and HPLC–DAD and anti-cholinesterase and anti-oxidant activities of Trifolium repens L. leaves', European Food Research and Technology, 246(3), pp. 485-496. doi:10.1007/s00217-019-03416-8 Preclinical
    https://doi.org/10.1007/s00217-019-03416-8
  24. Petrović, M. and Stanković, M. and Anđelković, B. and Babić, S. and Zornić, V. and Vasiljević, S. and Stevanović, Z.D (2016) 'Quality Parameters and Antioxidant Activity of Three Clover Species in Relation to the Livestock Diet', Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 44(1), pp. 201-208. doi:10.15835/nbha44110144 Preclinical
    https://doi.org/10.15835/nbha44110144
  25. Jakubczyk, K. and Łukomska, A. and Gutowska, I. and Kochman, J. and Janił, J. and Janda, K (2021) 'Edible Flowers Extracts as a Source of Bioactive Compounds with Antioxidant Properties—In Vitro Studies', Applied Sciences, 11(5), pp. 2120-2120. doi:10.3390/app11052120 Preclinical
    https://doi.org/10.3390/app11052120
  26. Ngangom, L. and Venugopal, D. and Pandey, N. and Kumar, N (2022) 'In-silico screening and identification of potential bioactive compounds of Trifolium repens against pathogenic bacterial target proteins', Materials Today Proceedings, 73, pp. 142-150. doi:10.1016/j.matpr.2022.09.501 Preclinical
    https://doi.org/10.1016/j.matpr.2022.09.501
  27. Amer, B. and Juul, L. and Møller, A.H. and Møller, H.S. and Dalsgaard, T.K (2020) 'Improved solubility of proteins from white and red clover – inhibition of redox enzymes', International Journal of Food Science & Technology, 56(1), pp. 302-311. doi:10.1111/ijfs.14632 Preclinical
    https://doi.org/10.1111/ijfs.14632
  28. Pap, N. and Granato, D. and Järvenpää, E. and Tienaho, J. and Marnila, P. and Hellström, J. and Pihlava, J. and Franco, M. and Stefański, T. and Rinne, M (2024) 'Biorefining of legume and grass biomasses: Technological properties and bioactivities of the green juice', Future Foods, 9, pp. 100331-100331. doi:10.1016/j.fufo.2024.100331 Preclinical
    https://doi.org/10.1016/j.fufo.2024.100331
  29. Ahn, C. and Lee, J. and Park, M.J. and Kim, J. and Yang, J. and Yoo, Y. and Jeung, E (2020) 'Cytostatic effects of plant essential oils on human skin and lung cells', Experimental and Therapeutic Medicine, 19(3), pp. 2008-2018. doi:10.3892/etm.2020.8460 Preclinical
    https://doi.org/10.3892/etm.2020.8460
  30. Bhattacharya, S. et al (2013) 'Review of the botanical, phytochemical, pharmacological and toxicological properties of white clover (Trifolium repens L.)', 7(7), pp. 583--588. Traditional / reference
    https://scholar.google.com/scholar?q=Review%20of%20the%20botanical%2C%20phytochemical%2C%20pharmacological%20and%20toxicological%20properties%20of%20white%20clover%20%28Trifolium%20repens%20L.%29
  31. Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
    https://scholar.google.com/scholar?q=A%20Modern%20Herbal
  32. Klaiber, I. et al (2002) 'Health benefits of isoflavones from clover species', 16(1), pp. 1--8. Traditional / reference
    https://scholar.google.com/scholar?q=Health%20benefits%20of%20isoflavones%20from%20clover%20species
  33. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.