Symptom → Plant Sources
Yellow loosestrife (Lysimachia vulgaris) as a tool for helping with Wounds
inferred from astringent/styptic traditional use
Nine heterosides, derivatives of kaempferol, quercetin and myricetin from the drug were isolated. Six glycosides were identified, and the structure of the three compounds was established partially, one of these is triglycoside of quercetin, the other two are the higher-molecular glycosides of quercetin and myricetin.
1 source supporting Yellow loosestrife for Wounds. Includes scientific publications, books, monographs and traditional-use references.
Mechanistic basis
This use is associated with the plant's antimicrobial, astringent actions. Further evidence for that pharmacology:
Background Lysimachia vulgaris L. (Yellow loosestrife) is a medicinal plant in the family Myrsinaceae. It has been used in the treatment of fever, ulcer, diarrhea and wounds in folk medicine. It has also analgesic, expectorant, astringent and anti-inflammatory activities. Two different sources of the plant (field-grown and in vitro -grown) were used to evaluate the biological activities (antibacterial, antitumor and antioxidant) of L. vulgaris. In vitro-grown plant materials were collected from L. vulgaris plants that were previously regenerated in our laboratory. Materials and methods Plant materials were extracted with water, ethanol and acetone. For antibacterial test, disc diffusion method and 10 different pathogenic bacteria were used. Antioxidant activity was indicated by using DPPH method. The total phenol amount by using Folin-Ciocaltaeu method and the total flavonoid amount by using aluminum chloride (AlCl 3 ) colorimetric method were determined. Results Generally, yellow loosestrife extracts demonstrated antibacterial activity against Gram-positive bacteria (Staphylococcus aureus, S. epidermidis and Streptococcus pyogenes) . Strong antitumor activity of yellow loosestrife was observed via potato disc diffusion bioassay. Nine different phenolics were also determined and compared by using High-Performance Liquid Chromatography (HPLC). Conclusion Future investigations should be focused on fractionation of the extracts to identify active components for biological activity.