Omnia SanaPlant Comparison
Motherwort vs Figwort
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Motherwort and Figwort: they share 5 indicated uses (arthritis / joint pain, inflammation (general), menstrual cramps, …); 2 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Motherwort | Figwort | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 2/10 | Comparable evidence |
| Menstrual cramps | 1/10 | 1/10 | Comparable evidence |
| Muscle spasm | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 2/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Leonurine and related iridoid/alkaloid-type constituents are considered the principal cardioactive and uterotonic compounds.
Antioxidant constituents contributing to the plant's anti-inflammatory activity.
Bitter diterpenes, shared with related Lamiaceae bitters, contributing to the traditional digestive and cardiac reputation.
Anti-inflammatory constituents; harpagoside also has cardiac (inotropic) activity.
Supporting antioxidant constituents.
Pharmacological Actions
Mild diuretic and lymphatic 'detoxifying' herb (traditional); Traditional 'alterative' for chronic skin conditions - eczema, psoriasis, rashes (as a poultice, salve or tea)
Antispasmodic / smooth-muscle relaxant (preclinical - an extract relaxed isolated intestinal smooth muscle, apparently via muscarinic receptors)
Mild diuretic and lymphatic 'detoxifying' herb (traditional)
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from sedative action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from alterative action
Traditional 'alterative' for chronic skin conditions - eczema, psoriasis, rashes (as a poultice, salve or tea)
inferred from anti-inflammatory action
inferred from antispasmodic action
Traditional 'alterative' for chronic skin conditions - eczema, psoriasis, rashes (as a poultice, salve or tea)
Anti-inflammatory; soothes inflamed, irritated skin; Traditional 'alterative' for chronic skin conditions - eczema, psoriasis, rashes (as a poultice, salve or tea)
inferred from diuretic action
inferred from diuretic action
Safety, Cautions & Contraindications
Contraindicated in pregnancy (uterine stimulant). Avoid in heavy menstrual bleeding. May enhance anticoagulant and antihypertensive drug effects. Avoid in thyroid disorders. Generally well tolerated in normal doses for short-term use.
Duke (2002) rates motherwort as ++ and notes hypotensive, cardiotonic (negative chronotropic), anti-aggregant, and sedative activities at the experimental level (score 1). The plant is traditionally used for heart palpitations, hypertension, and menstrual regulation in European herbalism. Duke emphasizes strong safety caution: motherwort has documented oxytocic (uterine-stimulating) activity and is strictly contraindicated in pregnancy. It may also enhance the effects of cardiac medications and sedatives (Duke, 2002).
Avoid if you have a heart condition or take cardiac medicines: figwort's harpagoside has a stimulating (inotropic) effect on the heart, so it is traditionally avoided with rapid heartbeat or heart disease.
Avoid during pregnancy. There is insufficient reliable evidence on the safety of taking figwort by mouth, so internal use should be cautious and short-term.
External Ids
Botanical Description
Tall, upright perennial herb with deeply palmately lobed lower leaves (giving a lion's-paw appearance, the source of the genus name) and progressively less-divided upper leaves. Small, pink to pale purple, spiny-toothed, two-lipped flowers are borne in dense whorls up the square stem.[1]
Tall perennial herb (Scrophulariaceae), 50-100 cm (occasionally more), with a distinctly square stem. Leaves are opposite, ovate, toothed and unpleasant-smelling. Small, dull maroon-brown, two-lipped flowers are borne in loose, branched clusters (cymes), followed by small dry seed capsules.[11]
Habitat
Grows on waste ground, roadsides, hedgerows and near old dwellings; native to Central Asia and southeastern Europe and long naturalised across Europe and North America.[1]
Native to Europe and western Asia, growing in damp woods, hedge banks, ditches and shady waste ground on moist, nutrient-rich soils.[11]
Harvesting
The flowering aerial parts (leaf, stem and flower) are cut in summer as the plant comes into flower, and dried in a warm, shaded, airy place.[1]
Aerial parts are cut during flowering (summer); the root can also be dug in autumn.[11]
Traditional Uses
Motherwort has a long European and Asian herbal tradition, reflected in its name, as a gynaecological and cardiac tonic, traditionally used for heart palpitations and nervous cardiac complaints, menstrual irregularities and cramps, and as a calming nervine for anxiety and to ease childbirth and postpartum recovery.[1, 6]
Figwort takes one common name, 'scrofula plant', from its historic traditional use for scrofula (tuberculous lymph-node swelling) under the Doctrine of Signatures, its knotty root resembling swollen glands. It has a long folk-medicine reputation as an 'alterative' (blood-purifying) herb for chronic skin conditions such as eczema and psoriasis, applied as a poultice, salve or tea.[11, 12]
Preparations
Dosage
The EU herbal monograph gives a single dose of 1.5-4.5 g of the comminuted herb for tea preparation, for a daily dose of 3-10 g, in adults and elderly; a 1:5 tincture in 45% V/V ethanol at 2-6 mL three times daily and a liquid extract at 2-4 mL three times daily are also listed. If symptoms persist longer than 4 weeks a healthcare practitioner should be consulted. Not recommended under 18 years. Educational reference only, not a prescription.
Traditional guidance suggests roughly 2-4 g dried herb per cup as an infusion, taken cautiously and short-term given limited safety data and the cardioactive harpagoside content. Educational reference only, not a prescription; avoid with heart conditions/cardiac medicines and in pregnancy.
References
Drug Class Interactions
Not documented
Lookalikes Review
Dangerous Lookalikes
Not documented
References & Sources
- Fierascu, R.C., Fierascu, I., Ortan, A., Fierascu, I.C. and others (2019) 'Leonurus cardiaca L. as a Source of Bioactive Compounds: An Update of the European Medicines Agency Assessment Report (2010)', BioMed Research International, 2019, pp. 4303215. doi:10.1155/2019/4303215 Traditional / reference
https://doi.org/10.1155/2019/4303215 - Wojtyniak, K., Szymanski, M. and Matlawska, I (2013) 'Leonurus cardiaca L. (motherwort): a review of its phytochemistry and pharmacology', Phytotherapy Research, 27(8), pp. 1115-1120. doi:10.1002/ptr.4850 Traditional / reference
https://doi.org/10.1002/ptr.4850 - Kuchta, K., Volk, R.B. and Rauwald, H.W (2013) 'Stachydrine in Leonurus cardiaca, Leonurus japonicus, Leonotis leonurus: detection and quantification by instrumental HPTLC and 1H-qNMR analyses', Pharmazie, 68(7), pp. 534-540. Available at: https://pubmed.ncbi.nlm.nih.gov/23923634/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/23923634/ - Kuchta, K., Volk, R.B. and Rauwald, H.W (2012) 'Leonurus japonicus, Leonurus cardiaca, Leonotis leonurus: a novel HPLC study on the occurrence and content of the pharmacologically active guanidino derivative leonurine', Pharmazie, 67(12), pp. 973-979. Available at: https://pubmed.ncbi.nlm.nih.gov/23346757/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/23346757/ - Koshovyi, O., Raal, A., Kireyev, I., Tryshchuk, N. and others (2021) 'Phytochemical and Psychotropic Research of Motherwort (Leonurus cardiaca L.) Modified Dry Extracts', Plants (Basel), 10(2), pp. 230. doi:10.3390/plants10020230 Preclinical
https://doi.org/10.3390/plants10020230 - Angeloni, S., Spinozzi, E., Maggi, F., Sagratini, G. and others (2021) 'Phytochemical Profile and Biological Activities of Crude and Purified Leonurus cardiaca Extracts', Plants (Basel), 10(2), pp. 195. doi:10.3390/plants10020195 Preclinical
https://doi.org/10.3390/plants10020195 - Sadowska, B., Wieckowska-Szakiel, M., Paszkiewicz, M. and Rozalska, B (2019) 'Molecular Mechanisms of Leonurus cardiaca L. Extract Activity in Prevention of Staphylococcal Endocarditis - Study on in Vitro and ex Vivo Models', Molecules, 24(18), pp. 3318. doi:10.3390/molecules24183318 Preclinical
https://doi.org/10.3390/molecules24183318 - Kuchta, K., Hladikova, J., Thomsen, M., Nguyen, A.D. and others (2025) 'Phenolic and Iridoid Glycosides from Leonurus cardiaca L. and Their Effects on the alpha, delta, and gamma Subtypes of the PPAR System', Molecules, 30(2), pp. 419. doi:10.3390/molecules30020419 Preclinical
https://doi.org/10.3390/molecules30020419 - Pereira, O.R., Catarino, M.D., Afonso, A.F., Silva, A.M.S. and Cardoso, S.M (2019) 'Hepatoprotection of Leonurus cardiaca L., Leonurus japonicus Houtt. and Leonurus sibiricus L', Antioxidants (Basel), 8(8), pp. 267. doi:10.3390/antiox8080267 Preclinical
https://doi.org/10.3390/antiox8080267 - Kuchta, K., Ortwein, J. and Rauwald, H.W (2014) '1H-qNMR for direct quantification of stachydrine in Leonurus japonicus and L. cardiaca', Fitoterapia, 96, pp. 8-17. doi:10.1016/j.fitote.2014.03.023 Preclinical
https://doi.org/10.1016/j.fitote.2014.03.023 - European Medicines Agency (HMPC) (2010) 'Community herbal monograph on Leonurus cardiaca L., herba'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-leonurus-cardiaca-l-herba_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-leonurus-cardiaca-l-herba_en.pdf - Kowalchik, C. and Hylton, W (1998) 'Rodale'. Traditional / reference
https://scholar.google.com/scholar?q=Rodale - Prajapati, N.D., Purohit, S.S., Sharma, A.K. and Kumar, T (2003) 'A Handbook of Medicinal Plants'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Handbook%20of%20Medicinal%20Plants - Shang, X. et al (2014) 'The genus Leonurus: traditional uses, phytochemistry and pharmacology', pp. 43--63. Traditional / reference
https://scholar.google.com/scholar?q=The%20genus%20Leonurus%3A%20traditional%20uses%2C%20phytochemistry%20and%20pharmacology - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003
- Stevenson, P.C., Simmonds, M.S.J., Sampson, J., Houghton, P.J. and Grice, P (2002) 'Wound healing activity of acylated iridoid glycosides from Scrophularia nodosa', Phytotherapy Research, 16(1), pp. 33-35. doi:10.1002/ptr.798 Preclinical
https://doi.org/10.1002/ptr.798 - Ahmad, M., Muhammad, N., Mehjabeen, Jahan, N. and others (2012) 'Biological screening of Scrophularia nodosa extract and its fractions', Pakistan Journal of Pharmaceutical Sciences, 25(2), pp. 307-313. Preclinical
https://scholar.google.com/scholar?q=Biological%20screening%20of%20Scrophularia%20nodosa%20extract%20and%20its%20fractions - Miyase, T. and Mimatsu, A (1999) 'Acylated iridoid and phenylethanoid glycosides from the aerial parts of Scrophularia nodosa', Journal of Natural Products, 62(8), pp. 1079-1084. doi:10.1021/np9805746 Preclinical
https://doi.org/10.1021/np9805746 - Sesterhenn, K., Distl, M. and Wink, M (2006) 'Occurrence of iridoid glycosides in in vitro cultures and intact plants of Scrophularia nodosa L', Plant Cell Reports, 26(3), pp. 365-371. doi:10.1007/s00299-006-0233-3 Preclinical
https://doi.org/10.1007/s00299-006-0233-3 - Soualeh, N., Stiévenard, A., Baudelaire, E., Bouayed, J. and Soulimani, R (2019) 'Powders with small microparticle size from Hedera helix and Scrophularia nodosa exhibited high preventive antioxidant activity against H2O2-induced oxidative stress in mouse primary spleen cells', International Journal for Vitamin and Nutrition Research, 88(3-4), pp. 208-218. doi:10.1024/0300-9831/a000526 Preclinical
https://doi.org/10.1024/0300-9831/a000526 - Papp, N., Czégényi, D., Tóth, M., Dénes, T. and others (2022) 'Ethnomedicine survey on folk dermatology in Transylvania, Romania', Clinics in Dermatology, 40(6), pp. 651-664. doi:10.1016/j.clindermatol.2022.07.013 Traditional / reference
https://doi.org/10.1016/j.clindermatol.2022.07.013 - Soulimani, R., Dicko, A., Baudelaire, E. and Bouayed, J (2021) 'Increased anti-inflammatory activity and enhanced phytochemical concentrations in superfine powders obtained by controlled differential sieving process from four medicinal plants', International Journal for Vitamin and Nutrition Research, 93(4), pp. 339-351. doi:10.1024/0300-9831/a000739 Preclinical
https://doi.org/10.1024/0300-9831/a000739 - Ohiienko, T., Kutsyk, R., Kurovets, L., Ohiienko, S. and others (2023) 'Screening of medicinal and aromatic plants extracts for the synergism with fluconazole against Candida albicans and Candida tropicalis fungi associated with denture stomatitis', Wiadomosci Lekarskie, 76(7), pp. 1615-1620. doi:10.36740/WLek202307115 Preclinical
https://doi.org/10.36740/WLek202307115 - Leclerc, H (1949) '[The scrofular, Scrophularia nodosa L.]', Revue de Phytotherapie, 13(87), pp. 381-383. Traditional / reference
https://scholar.google.com/scholar?q=%5BThe%20scrofular%2C%20Scrophularia%20nodosa%20L.%5D - Akerreta, S., Cavero, R.Y. and Calvo, M.I (2007) 'First comprehensive contribution to medical ethnobotany of Western Pyrenees', Journal of Ethnobiology and Ethnomedicine, 3, pp. 26. doi:10.1186/1746-4269-3-26 Traditional / reference
https://doi.org/10.1186/1746-4269-3-26 - Medicinal Herbals (n.d.) 'Figwort (Scrophularia nodosa): The Natural Skin Healer'. Available at: https://medicinalherbals.net/figwort-scrophularia-nodosa-natural-skin-healer/ Traditional / reference
https://medicinalherbals.net/figwort-scrophularia-nodosa-natural-skin-healer/ - WebMD (n.d.) 'Figwort: Overview, Uses, Side Effects, Precautions, Interactions'. Available at: https://www.webmd.com/vitamins/ai/ingredientmono-446/figwort Traditional / reference
https://www.webmd.com/vitamins/ai/ingredientmono-446/figwort - Ahmad, M., Muhammad, N., Mehjabeen, Jahan, N., Ahmad, M., Obaidullah, Qureshi, M. and Jan, S.U (2012) 'Spasmolytic effects of Scrophularia nodosa extract on isolated rabbit intestine', Pakistan Journal of Pharmaceutical Sciences, 25(1), pp. 267--275. Traditional / reference
https://scholar.google.com/scholar?q=Spasmolytic%20effects%20of%20Scrophularia%20nodosa%20extract%20on%20isolated%20rabbit%20intestine - First Nature 'Scrophularia nodosa, Common Figwort'. Available at: https://www.first-nature.com/flowers/scrophularia-nodosa.php Traditional / reference
https://www.first-nature.com/flowers/scrophularia-nodosa.php - Berdai, M.A. and Labib, S. and Chetouani, K. and Harandou, M (2012) 'Atropa belladonna intoxication: a case report', Pan African Medical Journal, 11, pp. 72. Available at: https://pubmed.ncbi.nlm.nih.gov/22655106/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/22655106/ - Oerlemans, C. and de Vries, I. and van Riel, A.J.H.P (2017) 'Anticholinergic syndrome caused by contaminated herbal tea; acting swiftly to identify the source', Nederlands Tijdschrift voor Geneeskunde, 161, pp. D1261. Available at: https://pubmed.ncbi.nlm.nih.gov/28612694/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/28612694/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.