Plant Comparison
Elecampane vs Sweet Violet
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Elecampane and Sweet Violet: they share 7 indicated uses (arthritis / joint pain, bronchitis, cancer (anticancer research), …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Elecampane | Sweet Violet | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 2/10 | 1/10 | Comparable evidence |
| Bronchitis | 1/10 | 5/10 | Stronger for Sweet Violet |
| Cancer (anticancer research) | 2/10 | 2/10 | Comparable evidence |
| Cough | 1/10 | 5/10 | Stronger for Sweet Violet |
| Inflammation (general) | 2/10 | 1/10 | Comparable evidence |
| Respiratory support | 1/10 | 6/10 | Stronger for Sweet Violet |
| Skin irritation | 2/10 | 5/10 | Stronger for Sweet Violet |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
The antimicrobial and anti-inflammatory principles of the root; the eudesmane core and the alpha,beta-methylene-lactone ring are essential for the antimicrobial activity.
A fructan polysaccharide abundant in the root (the genus Inula gives inulin its name).
Pharmacological Actions
Anti-inflammatory - sesquiterpene lactones (alantolactone, isoalantolactone) inhibit NF-kB and MAPK signalling and pro-inflammatory cytokines; total sesquiterpene lactones eased arthritis in animal models (potential in rheumatoid arthritis)
Antimicrobial, notably anti-staphylococcal (membrane-damaging) and anti-mycobacterial (active against Mycobacterium tuberculosis in vitro); supports respiratory and skin infection
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
Traditional & Indicated Uses
Anti-inflammatory - sesquiterpene lactones (alantolactone, isoalantolactone) inhibit NF-kB and MAPK signalling and pro-inflammatory cytokines; total sesquiterpene lactones eased arthritis in animal models (potential in rheumatoid arthritis)
Expectorant for productive cough and bronchitis (long-standing respiratory remedy)
inferred from anticancer action
Expectorant for productive cough and bronchitis (long-standing respiratory remedy); Soothes irritated airways / chronic catarrh (traditional)
Antimicrobial, notably anti-staphylococcal (membrane-damaging) and anti-mycobacterial (active against Mycobacterium tuberculosis in vitro); supports respiratory and skin infection
inferred from anti-inflammatory action
inferred from expectorant action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
inferred from anticancer action
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
Mild sedative for sleeplessness and to ease headache (traditional)
inferred from anti-inflammatory action
Mild sedative for sleeplessness and to ease headache (traditional)
inferred from expectorant action
inferred from demulcent action
Safety, Cautions & Contraindications
The sesquiterpene lactones (especially alantolactone) are known skin sensitisers and can cause allergic contact dermatitis; people sensitive to the daisy family (Asteraceae) should be cautious.
Large doses can cause nausea, vomiting and diarrhoea; safety in pregnancy and breastfeeding is not established, so avoid medicinal doses.
Generally well tolerated as flower/leaf preparations. It contains salicylates, so use caution if you are salicylate-sensitive; the root in large doses is emetic and purgative.
Safety in pregnancy and breastfeeding is not established, so avoid medicinal doses.
External Ids
Botanical Description
Tall, robust perennial herb with large, coarse, hairy leaves - broadly oval near the base and progressively smaller up the stem - arising from a thick, aromatic rhizome. Large, shaggy, bright yellow daisy-like flower heads with numerous narrow ray florets are borne at the top of stout, branching stems.[12]
Low, spreading perennial herb with heart-shaped, softly toothed leaves arising from a short rootstock, spreading by runners (stolons). Fragrant, deep violet-purple (occasionally white) flowers with five petals, the lower petal spurred, are borne singly on slender stalks.[11]
Habitat
Grows in damp meadows, pastures, roadsides and woodland margins on moist, rich soils; native to Europe and Western Asia and naturalised in North America.[12]
Grows in woodland edges, hedgerows, shaded banks and gardens on moist, humus-rich soils; native to Europe, North Africa and Asia and widely naturalised and cultivated elsewhere.[11]
Harvesting
The root and rhizome are dug in autumn of the second or later year, when sesquiterpene lactone and inulin content is highest, then cleaned, sliced and dried.[12]
Flowers are picked as they open in early spring; leaves can be gathered through the growing season and dried.[11]
Traditional Uses
Elecampane root has a long European tradition, reflected in the old name 'elf dock', as a warming expectorant remedy for productive cough, bronchitis and chronic respiratory catarrh, and topically and internally as an antimicrobial for skin and wound infections.[12]
Sweet violet flower and leaf have a long European folk history as a soothing demulcent and expectorant remedy for cough, bronchitis and catarrh, and as a mild sedative for sleeplessness and headache; the flower syrup in particular has a long tradition as a children's cough remedy.[11]
Preparations
Dried root simmered in water as a traditional expectorant and antimicrobial tea.
References
Lookalikes Review
Dosage
Not documented
A double-blind randomised placebo-controlled trial used 5 mL of Viola odorata syrup every 12 hours for 4 weeks as add-on therapy for insomnia. Traditional references suggest around 2-4 g of dried flower and leaf per cup, up to three times daily. Note the EU monograph on Violae herba cum flore covers Viola tricolor, a different species, and its posology does not transfer here. Educational reference only, not a prescription.
Drug Class Interactions
Not documented
Dangerous Lookalikes
Not documented
References & Sources
- Gierlikowska, B., Gierlikowski, W., Bekier, K., Skalicka-Wozniak, K., Czerwinska, M.E. and Kiss, A.K (2019) 'Inula helenium and Grindelia squarrosa as a source of compounds with anti-inflammatory activity in human neutrophils and cultured human respiratory epithelium', Journal of Ethnopharmacology, 249, pp. 112311. doi:10.1016/j.jep.2019.112311 Preclinical
https://doi.org/10.1016/j.jep.2019.112311 - Gao, S. and Wang, Q. and Tian, X.H. and Li, H.L. and Shen, Y.H. and Xu, X.K. and Wu, G.Z. and Hu, Z.L. and Zhang, W.D (2016) 'Total sesquiterpene lactones prepared from Inula helenium L. has potentials in prevention and therapy of rheumatoid arthritis', Journal of Ethnopharmacology, pp. 39--46. doi:10.1016/j.jep.2016.12.020 Preclinical
https://doi.org/10.1016/j.jep.2016.12.020 - Wang, Q., Gao, S., Wu, G., Yang, N., Zu, X., Li, W., Xie, N., Zhang, R., Li, C., Hu, Z. and Zhang, W (2018) 'Total sesquiterpene lactones isolated from Inula helenium L. attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice', Phytomedicine, 46, pp. 78-84. doi:10.1016/j.phymed.2018.04.036 Preclinical
https://doi.org/10.1016/j.phymed.2018.04.036 - Dao, T.T.P., Song, K., Kim, J.Y. and Kim, Y.S (2020) 'Igalan from Inula helenium (L.) suppresses the atopic dermatitis-like response in stimulated HaCaT keratinocytes via JAK/STAT3 signaling', Inflammation Research, 69(3), pp. 309-319. doi:10.1007/s00011-020-01322-4 Preclinical
https://doi.org/10.1007/s00011-020-01322-4 - He, X., Zhao, W., Shao, B., Zhang, B., Liu, T., Sun, C., Huang, H., Wu, J., Liang, J. and Ma, X (2020) 'Natural soluble epoxide hydrolase inhibitors from Inula helenium and their interactions with soluble epoxide hydrolase', International Journal of Biological Macromolecules, 161, pp. 1465-1474. doi:10.1016/j.ijbiomac.2020.04.227 Preclinical
https://doi.org/10.1016/j.ijbiomac.2020.04.227 - Buza, V., Niculae, M., Hanganu, D., Pall, E., Burtescu, R.F., Olah, N., Matei-Latiu, M., Vlasiuc, I., Iozon, I., Szakacs, A.R., Ielciu, I. and Stefanut, L.C (2022) 'Biological Activities and Chemical Profile of Gentiana asclepiadea and Inula helenium Ethanolic Extracts', Molecules, 27(11), pp. 3560. doi:10.3390/molecules27113560 Preclinical
https://doi.org/10.3390/molecules27113560 - Zheng, X., Wu, Z., Xu, J., Zhang, X., Tu, Y., Lei, J., Yuan, R., Cheng, H., Wang, Q. and Yu, J (2021) 'Bioactive sesquiterpenes from Inula helenium', Bioorganic Chemistry, 114, pp. 105066. doi:10.1016/j.bioorg.2021.105066 Preclinical
https://doi.org/10.1016/j.bioorg.2021.105066 - Nder, A.E (2021) 'Efficacy of methanol-water extract of Inula helenium root against oxidative DNA damage', Journal of Traditional Chinese Medicine, 41(2), pp. 293-300. Preclinical
https://scholar.google.com/scholar?q=Efficacy%20of%20methanol-water%20extract%20of%20Inula%20helenium%20root%20against%20oxidative%20DNA%20damage - Chun, J., Song, K. and Kim, Y.S (2018) 'Sesquiterpene lactones-enriched fraction of Inula helenium L. induces apoptosis through inhibition of signal transducers and activators of transcription 3 signaling pathway in MDA-MB-231 breast cancer cells', Phytotherapy Research, 32(12), pp. 2501-2509. doi:10.1002/ptr.6189 Preclinical
https://doi.org/10.1002/ptr.6189 - Li, Y., Ni, Z., Zhu, M., Dong, M., Wang, S., Shi, Q., Zhang, M., Wang, Y., Huo, C., Kiyota, H. and Cong, B (2012) 'Antitumour activities of sesquiterpene lactones from Inula helenium and Inula japonica', Zeitschrift fur Naturforschung C, 67(7-8), pp. 375-380. doi:10.1515/znc-2012-7-804 Preclinical
https://doi.org/10.1515/znc-2012-7-804 - Yan, Y.Y., Zhang, Q., Zhang, B., Yang, B. and Lin, N.M (2019) 'Active ingredients of Inula helenium L. exhibits similar anti-cancer effects as isoalantolactone in pancreatic cancer cells', Natural Product Research, 34(17), pp. 2539-2544. doi:10.1080/14786419.2018.1543676 Preclinical
https://doi.org/10.1080/14786419.2018.1543676 - Kenny, C.R., Stojakowska, A., Furey, A. and Lucey, B (2022) 'From Monographs to Chromatograms: The Antimicrobial Potential of Inula helenium L. (Elecampane) Naturalised in Ireland', Molecules. doi:10.3390/molecules27041406 Traditional / reference
https://doi.org/10.3390/molecules27041406 - Stojanovic-Radic, Z. and Comic, Lj. and Radulovic, N. and Blagojevic, P. and Denic, M. and Miltojevic, A. and Rajkovic, J. and Mihajilov-Krstev, T (2012) 'Antistaphylococcal activity of Inula helenium L. root essential oil: eudesmane sesquiterpene lactones induce cell membrane damage', European Journal of Clinical Microbiology & Infectious Diseases, 31(6), pp. 1015--1025. doi:10.1007/s10096-011-1400-1 Preclinical
https://doi.org/10.1007/s10096-011-1400-1 - Cantrell, C.L. and Abate, L. and Fronczek, F.R. and Franzblau, S.G. and Quijano, L. and Fischer, N.H (1999) 'Antimycobacterial eudesmanolides from Inula helenium and Rudbeckia subtomentosa', Planta Medica, 65(4), pp. 351--355. doi:10.1055/s-1999-14001 Preclinical
https://doi.org/10.1055/s-1999-14001
- Feyzabadi, Z., Ghorbani, F., Vazani, Y. and Zarshenas, M.M (2017) 'A Critical Review on Phytochemistry, Pharmacology of Viola odorata L. and Related Multipotential Products in Traditional Persian Medicine', Phytotherapy Research, 31(11), pp. 1669-1675. doi:10.1002/ptr.5909 Meta-analysis / review
https://doi.org/10.1002/ptr.5909 - Heger, T., Zatloukal, M., Kubala, M., Strnad, M. and others (2022) 'Procyanidin C1 from Viola odorata L. inhibits Na,K-ATPase', Scientific Reports, 12(1), pp. 7011. doi:10.1038/s41598-022-11086-y Preclinical
https://doi.org/10.1038/s41598-022-11086-y - Yousefnia, S., Naseri, D., Seyed Forootan, F., Tabatabaeian, M. and others (2020) 'Suppressive role of Viola odorata extract on malignant characters of mammosphere-derived breast cancer stem cells', Clinical & Translational Oncology, 22(9), pp. 1619-1634. doi:10.1007/s12094-020-02307-9 Preclinical
https://doi.org/10.1007/s12094-020-02307-9 - Tafazoli, V., Shahriari, M., Heydari, M., Nikbakht, H.A. and others (2020) 'The Effect of Viola odorata L. Oil for Fever in Children: A Randomized Triple-blinded Placebo-controlled Clinical Trial', Current Drug Discovery Technologies, 17(5), pp. 696-703. doi:10.2174/1570163816666190620142256 Randomized trial
https://doi.org/10.2174/1570163816666190620142256 - Rahimi, V.B., Askari, V.R., Emami, S.A. and Tayarani-Najaran, Z (2017) 'Anti-melanogenic activity of Viola odorata different extracts on B16F10 murine melanoma cells', Iranian Journal of Basic Medical Sciences, 20(3), pp. 242-249. doi:10.22038/ijbms.2017.8350 Preclinical
https://doi.org/10.22038/ijbms.2017.8350 - Adel Mehraban, M.S., Shirzad, M., Mohammad Taghizadeh Kashani, L., Ahmadian-Attari, M.M. and others (2022) 'Efficacy and safety of add-on Viola odorata L. in the treatment of COVID-19: A randomized double-blind controlled trial', Journal of Ethnopharmacology, 304, pp. 116058. doi:10.1016/j.jep.2022.116058 Randomized trial
https://doi.org/10.1016/j.jep.2022.116058 - Saleem, U., Hira, S., Anwar, F., Shah, M.A. and others (2021) 'Pharmacological Screening of Viola odorata L. for Memory-Enhancing Effect via Modulation of Oxidative Stress and Inflammatory Biomarkers', Frontiers in Pharmacology, 12, pp. 664832. doi:10.3389/fphar.2021.664832 Preclinical
https://doi.org/10.3389/fphar.2021.664832 - Shayesteh, M., Vaez-Mahdavi, M.R., Shams, J., Kamalinejad, M. and others (2020) 'Effects of Viola odorata as an Add-On Therapy on Insomnia in Patients with Obsession or Depression: A Pilot Randomized Double-Blind Placebo-Controlled Trial', Journal of Alternative and Complementary Medicine, 26(5), pp. 398-408. doi:10.1089/acm.2019.0254 Randomized trial
https://doi.org/10.1089/acm.2019.0254 - Feyzabadi, Z., Jafari, F., Kamali, S.H., Ashayeri, H. and others (2014) 'Efficacy of Viola odorata in Treatment of Chronic Insomnia', Iranian Red Crescent Medical Journal, 16(12), pp. e17511. doi:10.5812/ircmj.17511 Clinical study
https://doi.org/10.5812/ircmj.17511 - Parsley, N.C., Kirkpatrick, C.L., Crittenden, C.M., Rad, J.G. and others (2018) 'PepSAVI-MS reveals anticancer and antifungal cycloviolacins in Viola odorata', Phytochemistry, 152, pp. 61-70. doi:10.1016/j.phytochem.2018.04.014 Preclinical
https://doi.org/10.1016/j.phytochem.2018.04.014 - Herbal Reality (n.d.) 'Violets (Viola odorata): Benefits, Safety, Uses'. Available at: https://www.herbalreality.com/herb/violets/ Traditional / reference
https://www.herbalreality.com/herb/violets/ - Qasemzadeh, M.J., Sharifi, H., Hamedanian, M., Gharehbeglou, M., Heydari, M., Sardari, M., Akhlaghdoust, M. and Minae, M.B (2015) 'The Effect of Viola odorata Flower Syrup on the Cough of Children With Asthma: A Double-Blind, Randomized Controlled Trial', Journal of Evidence-Based Complementary & Alternative Medicine, 20(4), pp. 287--291. doi:10.1177/2156587215584862 Randomized trial
https://doi.org/10.1177/2156587215584862 - RxList (n.d.) 'Sweet Violet: Health Benefits, Side Effects, Uses, Dose & Precautions'. Available at: https://www.rxlist.com/supplements/sweet_violet.htm Traditional / reference
https://www.rxlist.com/supplements/sweet_violet.htm - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003 - Unruly Gardening 'Foraging Violets: How to Identify, Harvest and Use'. Available at: https://unrulygardening.com/foraging-violets/ Traditional / reference
https://unrulygardening.com/foraging-violets/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.