Plant Comparison
Dropwort vs Japanese Rose
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Dropwort and Japanese Rose: both belong to the Rosaceae family; they share 3 indicated uses (cancer (anticancer research), inflammation (general), arthritis / joint pain); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Dropwort | Japanese Rose | Verdict |
|---|---|---|---|
| Cancer (anticancer research) | 2/10 | 2/10 | Comparable evidence |
| Inflammation (general) | 2/10 | 7/10 | Stronger for Japanese Rose |
| Arthritis / joint pain | 2/10 | 7/10 | Stronger for Japanese Rose |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Flavonol glycosides including spiraeoside (quercetin 4'-O-glucoside), hyperoside, rutin and kaempferol derivatives - the signature Filipendula flavonoids.
Ellagitannins and gallotannins (astringent constituents), giving the traditional astringent/antidiarrhoeal action.
Gallic, caffeic, chlorogenic and ferulic acids; antioxidant.
Catechin-based condensed tannins.
The dominant bioactive class, driving much of the antioxidant and anti-inflammatory activity.
Studied for immunomodulatory, hepatoprotective and gut-microbiota-modulating effects.
Concentrated in the hips, underpinning their traditional food-tonic use.
Isolated from the root and studied for antioxidant/neuroprotective activity.
Pharmacological Actions
Antihyperalgesic in a rat inflammatory-pain model (salicylate-mediated).
Traditional use for rheumatic/arthritic pain, consistent with salicylate content and analgesic/anti-inflammatory activity.
Protective against carbon-tetrachloride liver injury in rats.
Hydrolysable-tannin astringency underlying traditional antidiarrhoeal and wound/gargle use.
Nootropic and brain-bioenergetic effects in animal models (Russian traditional nervous-system use).
Dropwort extract restrained the YAP/TAZ/TEAD oncogenic axis in mesothelioma (preclinical).
Traditional & Indicated Uses
inferred from anticancer action
inferred from anti-rheumatic / analgesic action (salicylates)
inferred from astringent (tannin) action and traditional use
inferred from astringent/antimicrobial action and traditional wound-wash use
inferred from antimicrobial action
Nootropic (cognition-enhancing) activity in animals.
inferred from nootropic/neuroprotective action
inferred from traditional kidney/bladder 'gravel' use
inferred from traditional urinary/gravel use
inferred from anti-inflammatory action
inferred from anticancer action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
Dropwort contains salicylate compounds (salicylaldehyde, methyl salicylate), as in meadowsweet and willow. Avoid in salicylate or aspirin sensitivity, and use caution alongside anticoagulant or antiplatelet medicines. As with other salicylate-containing plants, avoid in children with viral illness (theoretical Reye's syndrome risk).
Safety in pregnancy and breastfeeding has not been established; avoid medicinal doses during pregnancy and lactation.
Generally safe as a food plant. Rose hips should be used after removing the achenes (seeds and inner hairs), which can cause irritation. Allergic reactions are rare. No significant drug interactions documented.
External Ids
Synonyms
Not documented
Botanical Description
Erect perennial herb of the rose family, 20-80 cm tall, growing from a short rootstock whose fibrous roots bear characteristic small tuber-like swellings (the 'drop-wort' beads). The leaves are mostly in a basal rosette and are distinctive: long, fern-like and interruptedly pinnate, with many (up to 20+ pairs) small, deeply toothed leaflets. Small creamy-white flowers, often pink-tinged in bud and 6-petalled, are borne in an irregular terminal cyme. Unlike its sibling meadowsweet (Filipendula ulmaria) of wet ground, dropwort grows in dry calcareous grassland.[1, 6]
Dense, thicket-forming deciduous shrub (Rosaceae), 1-1.5 m tall (occasionally to 2 m), with stems densely covered in numerous straight, bristly thorns. Leaves are pinnate with 5-9 deeply veined, glossy, leathery leaflets. Large, fragrant, deep pink to white, five-petalled flowers are followed by large, tomato-red, flattened-globose hips.[2]
Habitat
Dry, unimproved calcareous (chalk and limestone) grassland, meadows, roadside banks and open scrub. Native across most of Europe, western Asia and North Africa. Unlike meadowsweet (F. ulmaria), which grows in wet meadows and beside water, dropwort is a plant of dry ground.[1]
Native to coastal eastern Asia (Japan, Korea, China, far-eastern Russia), typically growing on sand dunes and coastal scrub. Widely planted and naturalised as an ornamental and hedging shrub, notably tolerant of salt spray, wind and poor sandy soils, in temperate coastal regions worldwide.[2]
Harvesting
The flowering tops and aerial parts are gathered in summer while in flower; the fern-like leaves and the small root tubers are also used. The material is dried for infusions and decoctions.[2]
Flowers/petals are picked as they open in summer; hips are picked in autumn once fully coloured and slightly softened.[2]
Traditional Uses
Dropwort shares much of the European folk-medicine history of its sibling meadowsweet. The salicylate- and tannin-rich herb has been used as an astringent and anti-inflammatory remedy for diarrhoea and other gastrointestinal complaints, for rheumatic and arthritic pain, for kidney and bladder 'gravel' and urinary complaints, and as a wound and mouth wash. In Serbian and Balkan ethnomedicine the flowers and roots are used; Russian traditional medicine uses dropwort extracts as a nootropic and calming remedy for the nervous system.[2, 12, 15]
Rosa rugosa has a long East Asian tradition - particularly in Traditional Chinese Medicine, where the flower is known as 'Mei Gui Hua' - as a mood-regulating, digestive and menstrual-cycle-supporting remedy, and the vitamin-C-rich hips are used as a food tonic. Modern research on its flavonoid- and polysaccharide-rich extracts supports broad antioxidant, anti-inflammatory, hepatoprotective and immunomodulatory activity.[2]
Preparations
Dried flowering tops or leaves infused as an astringent, anti-inflammatory tea for digestive and rheumatic complaints.
The root and root-tubers decocted; used traditionally for diarrhoea and urinary 'gravel'.
The flowers yield an aromatic oil dominated by salicylaldehyde with antimicrobial activity (as in meadowsweet).
References
Drug Class Interactions
Not documented
Pairings
Sibling species: both are salicylate- and tannin-rich Rosaceae with overlapping anti-inflammatory, analgesic, astringent and gastroprotective uses (dropwort of dry grassland, meadowsweet of wet meadows); studied together in the same trials.[2, 3]
Both are salicylate-containing anti-inflammatory and analgesic herbs (the classic plant-aspirin group), traditionally combined for rheumatic pain and fever.[10]
Rosaceae astringents rich in hydrolysable tannins, traditionally used for diarrhoea and as gargles; studied together for antioxidant and genotoxicity profile.[16]
Not documented
Lookalikes Review
Dangerous Lookalikes
Not documented
Dosage
Not documented
Traditional guidance suggests roughly 3-6 g dried flower per cup as an infusion, or hip tea/syrup at similar strength, taken once or twice daily. Educational reference only, not a prescription.
References & Sources
- Katanic, J. and Pferschy-Wenzig, E. and Mihailovic, V. and Boroja, T. and Pan, S. and Nikles, S. and Kretschmer, N. and Rosic, G. and Selakovic, D. and Joksimovic, J. and Bauer, R (2018) 'Phytochemical analysis and anti-inflammatory effects of Filipendula vulgaris Moench extracts', Food and Chemical Toxicology, 122, pp. 151-162. doi:10.1016/j.fct.2018.10.001 Preclinical
https://doi.org/10.1016/j.fct.2018.10.001 - Samardzic, S. and Arsenijevic, J. and Bozic, D. and Milenkovic, M. and Tesevic, V. and Maksimovic, Z (2018) 'Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench', Journal of Ethnopharmacology, 213, pp. 132-137. doi:10.1016/j.jep.2017.11.013 Preclinical
https://doi.org/10.1016/j.jep.2017.11.013 - Samardzic, S. and Tomic, M. and Pecikoza, U. and Stepanovic-Petrovic, R. and Maksimovic, Z (2016) 'Antihyperalgesic activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench in a rat model of inflammation', Journal of Ethnopharmacology, 193, pp. 652-656. doi:10.1016/j.jep.2016.10.024 Preclinical
https://doi.org/10.1016/j.jep.2016.10.024 - Maksimovic, Z. and Petrovic, S. and Pavlovic, M. and Kovacevic, N. and Kukic, J (2007) 'Antioxidant activity of Filipendula hexapetala flowers', Fitoterapia, 78(3), pp. 265-267. doi:10.1016/j.fitote.2007.01.004 Preclinical
https://doi.org/10.1016/j.fitote.2007.01.004 - Cebovic, T. and Maksimovic, Z (2011) 'Hepatoprotective effect of Filipendula hexapetala Gilib. (Rosaceae) in carbon tetrachloride-induced hepatotoxicity in rats', Phytotherapy Research, 26(7), pp. 1088-1091. doi:10.1002/ptr.3703 Preclinical
https://doi.org/10.1002/ptr.3703 - Katanic, J. and Mihailovic, V. and Stankovic, N. and Boroja, T. and Mladenovic, M. and Solujic, S. and Stankovic, M.S. and Vrvic, M.M (2015) 'Dropwort (Filipendula hexapetala Gilib.): potential role as antioxidant and antimicrobial agent', EXCLI Journal, 14, pp. 1-20. doi:10.17179/excli2014-479 Preclinical
https://doi.org/10.17179/excli2014-479 - Matic, S. and Katanic, J. and Stanic, S. and Mladenovic, M. and Stankovic, N. and Mihailovic, V. and Boroja, T (2015) 'In vitro and in vivo assessment of the genotoxicity and antigenotoxicity of the Filipendula hexapetala and Filipendula ulmaria methanol extracts', Journal of Ethnopharmacology, 174, pp. 287-292. doi:10.1016/j.jep.2015.08.025 Preclinical
https://doi.org/10.1016/j.jep.2015.08.025 - Bousetla, A. and Erol, E. and Benarous, K. and Topcu, G. and Laouer, H. and Akkal, S. and Boulebd, H (2025) 'LC-HRESIMS-Guided Phytochemical Characterization and Bioactivity Evaluation of Filipendula hexapetala Gilib. From Algeria: Antioxidant and Anticholinesterase Potential', Chemistry and Biodiversity, 22(11), pp. e01270. doi:10.1002/cbdv.202501270 Preclinical
https://doi.org/10.1002/cbdv.202501270 - Fandakli, S. and Korkmaz, B. and Faiz, O. and Kilic, G. and Erik, I. and Terzioglu, S. and Yayli, N (2021) 'Chemical Variation, Antimicrobial, Nitric Oxide Scavenging Activities and Tyrosinase Inhibition of Essential Oils and Solvent Extracts from Filipendula vulgaris Moench Growing in Turkey', Iranian Journal of Pharmaceutical Research, 20(3), pp. 110-120. doi:10.22037/ijpr.2021.114302.14786 Preclinical
https://doi.org/10.22037/ijpr.2021.114302.14786 - Radulovic, N. and Misic, M. and Aleksic, J. and Dokovic, D. and Palic, R. and Stojanovic, G (2007) 'Antimicrobial synergism and antagonism of salicylaldehyde in Filipendula vulgaris essential oil', Fitoterapia, 78(7-8), pp. 565-570. doi:10.1016/j.fitote.2007.03.022 Preclinical
https://doi.org/10.1016/j.fitote.2007.03.022 - Pulito, C. and Korita, E. and Sacconi, A. and Valerio, M. and Casadei, L. and Lo Sardo, F. and Mori, F. and Ferraiuolo, M. and Grasso, G. and Maidecchi, A. and Lucci, J. and Sudol, M. and Muti, P. and Blandino, G. and Strano, S (2019) 'Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma', Journal of Experimental and Clinical Cancer Research, 38(1), pp. 349. doi:10.1186/s13046-019-1352-3 Preclinical
https://doi.org/10.1186/s13046-019-1352-3 - Shilova, I.V. and Suslov, N.I (2015) 'Nootropic effect of meadowsweet (Filipendula vulgaris) extracts', Bulletin of Experimental Biology and Medicine, 158(5), pp. 659-663. doi:10.1007/s10517-015-2841-9 Preclinical
https://doi.org/10.1007/s10517-015-2841-9 - Shilova, I.V. and Suslov, N.I. and Amelchenko, V.P (2015) 'Nootropic Effects of Filipendula vulgaris Moench Water Extract Fractions', Bulletin of Experimental Biology and Medicine, 159(3), pp. 376-379. doi:10.1007/s10517-015-2967-9 Preclinical
https://doi.org/10.1007/s10517-015-2967-9 - Vengerovsky, A.I. and Suslov, N.I. and Kaygorodsev, A.V (2011) 'Effect of meadowsweet (Filipendula vulgaris) extract on bioenergetics of the brain during experimental posthypoxic encephalopathy', Bulletin of Experimental Biology and Medicine, 151(4), pp. 421-424. doi:10.1007/s10517-011-1346-4 Preclinical
https://doi.org/10.1007/s10517-011-1346-4 - Vengerovskii, A.I. and Suslov, N.I. and Kaigorodtsev, A.V (2011) 'Correction of experimental anxiety behavior by meadowsweet (Filipendula vulgaris) extracts', Eksperimental'naia i Klinicheskaia Farmakologiia, 74(9), pp. 3-6. Preclinical
https://scholar.google.com/scholar?q=Correction%20of%20experimental%20anxiety%20behavior%20by%20meadowsweet%20%28Filipendula%20vulgaris%29%20extracts - Pukalskiene, M. and Slapsyte, G. and Dedonyte, V. and Lazutka, J.R. and Mierauskiene, J. and Venskutonis, P.R (2017) 'Genotoxicity and antioxidant activity of five Agrimonia and Filipendula species plant extracts evaluated by comet and micronucleus assays in human lymphocytes and Ames Salmonella/microsome test', Food and Chemical Toxicology, 113, pp. 303-313. doi:10.1016/j.fct.2017.12.031 Preclinical
https://doi.org/10.1016/j.fct.2017.12.031 - Mitchell, M.I. and Routledge, P.A (1978) 'Hemlock water dropwort poisoning - a review', Clinical Toxicology, 12(4), pp. 417-26. doi:10.3109/15563657809150012 Clinical study
https://doi.org/10.3109/15563657809150012
- Zhang, Z., Hu, W., Yu, A., Bai, M. and others (2024) 'Physicochemical properties, health benefits, and applications of the polysaccharides from Rosa rugosa Thunb.: A review', International Journal of Biological Macromolecules, 282(Pt 3), pp. 136975. doi:10.1016/j.ijbiomac.2024.136975 Traditional / reference
https://doi.org/10.1016/j.ijbiomac.2024.136975 - Dong, X., Li, Y., Yang, K., Zhang, L. and others (2024) 'Total flavonoids from Rosa rugosa Thunb.: A comprehensive review of its extraction and purification process, chemical composition, biological effect and applications', Naunyn-Schmiedeberg's Archives of Pharmacology, 398(3), pp. 2343-2363. doi:10.1007/s00210-024-03504-x Traditional / reference
https://doi.org/10.1007/s00210-024-03504-x - Kim, J., Lee, S., Park, H. and others (2024) 'Hair Growth Effect and the Mechanisms of Rosa rugosa Extract in DHT-Induced Alopecia Mice Model', International Journal of Molecular Sciences, 25(21), pp. 11362. doi:10.3390/ijms252111362 Preclinical
https://doi.org/10.3390/ijms252111362 - Baiyisaiti, A., Liu, Y., Zhang, J. and Yang, R (2019) 'Rosa rugosa flavonoids exhibited PPAR-alpha agonist-like effects on genetic severe hypertriglyceridemia of mice', Journal of Ethnopharmacology, 240, pp. 111952. doi:10.1016/j.jep.2019.111952 Preclinical
https://doi.org/10.1016/j.jep.2019.111952 - Lei, L., Zhu, Y., Gao, W., Du, X. and others (2023) 'Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in Hepatocytes', Molecules, 28(21), pp. 7307. doi:10.3390/molecules28217307 Preclinical
https://doi.org/10.3390/molecules28217307 - Dai, C., Zheng, X., Zhu, J., Zhang, H. and others (2025) 'Polysaccharides derived from Rosa rugosa cv. Plena ameliorate colorectal cancer by regulating intestinal microbiota composition and lipid metabolism pathway', NPJ Science of Food, 9(1), pp. 176. doi:10.1038/s41538-025-00544-2 Preclinical
https://doi.org/10.1038/s41538-025-00544-2 - Chen, M., Peng, Y., Zhu, R., Luo, X. and others (2025) 'Therapeutic potential of Rosa rugosa polysaccharide and its nanofiber membrane in psoriasis via PI3K-AKT/mTOR pathway inhibition', International Journal of Biological Macromolecules, 320(Pt 2), pp. 145724. doi:10.1016/j.ijbiomac.2025.145724 Preclinical
https://doi.org/10.1016/j.ijbiomac.2025.145724 - Park, C.K., Choi, S.J., Kim, C.R., Shin, H.R. and others (2025) 'Ethanolic Extract of Rosa rugosa Roots and Its Bioactive Compound, Oleamide, Prevented Amyloid beta-Induced Oxidative Stress and Improved Behavioral Tests in Mice', International Journal of Molecular Sciences, 26(9), pp. 4214. doi:10.3390/ijms26094214 Preclinical
https://doi.org/10.3390/ijms26094214 - Ashraf, S., Ashraf, M.Z., Miao, B. and Zhao, X (2025) 'Optimizing Extraction Methods for Bioactive Polysaccharides from Rosa rugosa and Rosa damascena', Foods, 14(18), pp. 3211. doi:10.3390/foods14183211 Traditional / reference
https://doi.org/10.3390/foods14183211 - Liu, X., Liu, H., Zhang, Y. and others (2022) 'Rosa rugosa polysaccharide induces autophagy-mediated apoptosis in human cervical cancer cells via the PI3K/AKT/mTOR pathway', International Journal of Biological Macromolecules, 212, pp. 257-274. doi:10.1016/j.ijbiomac.2022.05.023 Preclinical
https://doi.org/10.1016/j.ijbiomac.2022.05.023 - Chrubasik, C., Roufogalis, B.D., Müller-Ladner, U. and Chrubasik, S (2008) 'A systematic review on the Rosa canina effect and efficacy profiles', 22(6), pp. 725--733. doi:10.1002/ptr.2400 Meta-analysis / review
https://doi.org/10.1002/ptr.2400 - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.