Plant Comparison
Dropwort vs Bay Leaf
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Dropwort and Bay Leaf: they share 9 indicated uses (cancer (anticancer research), inflammation (general), pain (general), …); 6 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Dropwort | Bay Leaf | Verdict |
|---|---|---|---|
| Cancer (anticancer research) | 2/10 | 2/10 | Comparable evidence |
| Inflammation (general) | 2/10 | 1/10 | Comparable evidence |
| Pain (general) | 2/10 | 1/10 | Comparable evidence |
| Arthritis / joint pain | 2/10 | 1/10 | Comparable evidence |
| Indigestion | 2/10 | 1/10 | Comparable evidence |
| Wounds | 2/10 | 1/10 | Comparable evidence |
| Infection (general) | 2/10 | 1/10 | Comparable evidence |
| Memory | 2/10 | 1/10 | Comparable evidence |
| Cognitive function | 2/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Flavonol glycosides including spiraeoside (quercetin 4'-O-glucoside), hyperoside, rutin and kaempferol derivatives - the signature Filipendula flavonoids.
Ellagitannins and gallotannins (astringent constituents), giving the traditional astringent/antidiarrhoeal action.
Gallic, caffeic, chlorogenic and ferulic acids; antioxidant.
Catechin-based condensed tannins.
Leaf essential oil dominated by 1,8-cineole and eugenol, giving the characteristic aroma and much of the antimicrobial and anti-inflammatory activity.
Contribute to the plant's anti-inflammatory and antioxidant activity.
Pharmacological Actions
Antihyperalgesic in a rat inflammatory-pain model (salicylate-mediated).
Traditional use for rheumatic/arthritic pain, consistent with salicylate content and analgesic/anti-inflammatory activity.
Protective against carbon-tetrachloride liver injury in rats.
Hydrolysable-tannin astringency underlying traditional antidiarrhoeal and wound/gargle use.
Nootropic and brain-bioenergetic effects in animal models (Russian traditional nervous-system use).
Dropwort extract restrained the YAP/TAZ/TEAD oncogenic axis in mesothelioma (preclinical).
Traditional & Indicated Uses
inferred from anticancer action
inferred from anti-rheumatic / analgesic action (salicylates)
inferred from astringent (tannin) action and traditional use
inferred from astringent/antimicrobial action and traditional wound-wash use
inferred from antimicrobial action
Nootropic (cognition-enhancing) activity in animals.
inferred from nootropic/neuroprotective action
inferred from traditional kidney/bladder 'gravel' use
inferred from traditional urinary/gravel use
inferred from anti-inflammatory action
inferred from analgesic action
inferred from digestive action
inferred from vulnerary action
inferred from anticancer action
inferred from neuroprotective action
inferred from analgesic action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from neuroprotective action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
Dropwort contains salicylate compounds (salicylaldehyde, methyl salicylate), as in meadowsweet and willow. Avoid in salicylate or aspirin sensitivity, and use caution alongside anticoagulant or antiplatelet medicines. As with other salicylate-containing plants, avoid in children with viral illness (theoretical Reye's syndrome risk).
Safety in pregnancy and breastfeeding has not been established; avoid medicinal doses during pregnancy and lactation.
Generally safe when used in food amounts. Not toxic to people and safe to cook with. Leaves are very rigid and leathery - should be removed before eating as they don't soften with cooking and edges can be sharp. Insufficient reliable information about safety during pregnancy or breastfeeding - stick to food amounts. Large amounts of bay leaf tea may cause vomiting (emetic properties) and drowsiness (sedative properties). In high doses, bay laurel has cytotoxic activity. Some people may experience allergic contact dermatitis from bay laurel oil.
Duke (2002) notes antibacterial, anti-inflammatory, and antioxidant activities for bay laurel, primarily at the experimental level. The essential oil contains eugenol and 1,8-cineole as principal bioactive components. Traditional dosages in European phytotherapy include 1–3 g of dried leaf as a tea. Caution is advised as the essential oil may cause allergic contact dermatitis, and bay berries should not be confused with the less toxic leaves (Duke, 2002).
External Ids
Synonyms
Not documented
Botanical Description
Erect perennial herb of the rose family, 20-80 cm tall, growing from a short rootstock whose fibrous roots bear characteristic small tuber-like swellings (the 'drop-wort' beads). The leaves are mostly in a basal rosette and are distinctive: long, fern-like and interruptedly pinnate, with many (up to 20+ pairs) small, deeply toothed leaflets. Small creamy-white flowers, often pink-tinged in bud and 6-petalled, are borne in an irregular terminal cyme. Unlike its sibling meadowsweet (Filipendula ulmaria) of wet ground, dropwort grows in dry calcareous grassland.[1, 6]
Evergreen shrub or small tree with dark green, glossy, aromatic leaves, smooth-edged and slightly wavy at the margin. Small, pale yellow-green flowers are borne in clusters in the leaf axils in spring, followed by small, dark purple-black berries on female trees.[11]
Habitat
Dry, unimproved calcareous (chalk and limestone) grassland, meadows, roadside banks and open scrub. Native across most of Europe, western Asia and North Africa. Unlike meadowsweet (F. ulmaria), which grows in wet meadows and beside water, dropwort is a plant of dry ground.[1]
Native to the Mediterranean region; widely cultivated as a culinary herb and ornamental tree in warm-temperate and Mediterranean climates worldwide.[11]
Harvesting
The flowering tops and aerial parts are gathered in summer while in flower; the fern-like leaves and the small root tubers are also used. The material is dried for infusions and decoctions.[2]
Leaves are picked year-round from established plants and used fresh or dried; berries/seed are collected once ripe in autumn.
Traditional Uses
Dropwort shares much of the European folk-medicine history of its sibling meadowsweet. The salicylate- and tannin-rich herb has been used as an astringent and anti-inflammatory remedy for diarrhoea and other gastrointestinal complaints, for rheumatic and arthritic pain, for kidney and bladder 'gravel' and urinary complaints, and as a wound and mouth wash. In Serbian and Balkan ethnomedicine the flowers and roots are used; Russian traditional medicine uses dropwort extracts as a nootropic and calming remedy for the nervous system.[2, 12, 15]
Bay leaf has an ancient Mediterranean culinary and medicinal history, used as a digestive carminative for indigestion and bloating, and topically and traditionally for muscle and joint pain and minor wounds; it remains one of the most widely used culinary herbs worldwide.[11]
Preparations
Dried flowering tops or leaves infused as an astringent, anti-inflammatory tea for digestive and rheumatic complaints.
The root and root-tubers decocted; used traditionally for diarrhoea and urinary 'gravel'.
The flowers yield an aromatic oil dominated by salicylaldehyde with antimicrobial activity (as in meadowsweet).
Dried leaf infused in hot water as a traditional digestive tea.
References
Drug Class Interactions
Not documented
Pairings
Sibling species: both are salicylate- and tannin-rich Rosaceae with overlapping anti-inflammatory, analgesic, astringent and gastroprotective uses (dropwort of dry grassland, meadowsweet of wet meadows); studied together in the same trials.[2, 3]
Both are salicylate-containing anti-inflammatory and analgesic herbs (the classic plant-aspirin group), traditionally combined for rheumatic pain and fever.[10]
Rosaceae astringents rich in hydrolysable tannins, traditionally used for diarrhoea and as gargles; studied together for antioxidant and genotoxicity profile.[16]
Not documented
Lookalikes Review
Dangerous Lookalikes
Dosage
Not documented
Two clinical studies in healthy volunteers used an infusion prepared from 5 g of dried Laurus nobilis leaves in 100 mL of boiled water, taken once daily for 10 days. Traditional references suggest a smaller 1-3 g per cup up to three times daily; no EMA or WHO monograph exists for bay leaf. Educational reference only, not a prescription.
References & Sources
- Katanic, J. and Pferschy-Wenzig, E. and Mihailovic, V. and Boroja, T. and Pan, S. and Nikles, S. and Kretschmer, N. and Rosic, G. and Selakovic, D. and Joksimovic, J. and Bauer, R (2018) 'Phytochemical analysis and anti-inflammatory effects of Filipendula vulgaris Moench extracts', Food and Chemical Toxicology, 122, pp. 151-162. doi:10.1016/j.fct.2018.10.001 Preclinical
https://doi.org/10.1016/j.fct.2018.10.001 - Samardzic, S. and Arsenijevic, J. and Bozic, D. and Milenkovic, M. and Tesevic, V. and Maksimovic, Z (2018) 'Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench', Journal of Ethnopharmacology, 213, pp. 132-137. doi:10.1016/j.jep.2017.11.013 Preclinical
https://doi.org/10.1016/j.jep.2017.11.013 - Samardzic, S. and Tomic, M. and Pecikoza, U. and Stepanovic-Petrovic, R. and Maksimovic, Z (2016) 'Antihyperalgesic activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench in a rat model of inflammation', Journal of Ethnopharmacology, 193, pp. 652-656. doi:10.1016/j.jep.2016.10.024 Preclinical
https://doi.org/10.1016/j.jep.2016.10.024 - Maksimovic, Z. and Petrovic, S. and Pavlovic, M. and Kovacevic, N. and Kukic, J (2007) 'Antioxidant activity of Filipendula hexapetala flowers', Fitoterapia, 78(3), pp. 265-267. doi:10.1016/j.fitote.2007.01.004 Preclinical
https://doi.org/10.1016/j.fitote.2007.01.004 - Cebovic, T. and Maksimovic, Z (2011) 'Hepatoprotective effect of Filipendula hexapetala Gilib. (Rosaceae) in carbon tetrachloride-induced hepatotoxicity in rats', Phytotherapy Research, 26(7), pp. 1088-1091. doi:10.1002/ptr.3703 Preclinical
https://doi.org/10.1002/ptr.3703 - Katanic, J. and Mihailovic, V. and Stankovic, N. and Boroja, T. and Mladenovic, M. and Solujic, S. and Stankovic, M.S. and Vrvic, M.M (2015) 'Dropwort (Filipendula hexapetala Gilib.): potential role as antioxidant and antimicrobial agent', EXCLI Journal, 14, pp. 1-20. doi:10.17179/excli2014-479 Preclinical
https://doi.org/10.17179/excli2014-479 - Matic, S. and Katanic, J. and Stanic, S. and Mladenovic, M. and Stankovic, N. and Mihailovic, V. and Boroja, T (2015) 'In vitro and in vivo assessment of the genotoxicity and antigenotoxicity of the Filipendula hexapetala and Filipendula ulmaria methanol extracts', Journal of Ethnopharmacology, 174, pp. 287-292. doi:10.1016/j.jep.2015.08.025 Preclinical
https://doi.org/10.1016/j.jep.2015.08.025 - Bousetla, A. and Erol, E. and Benarous, K. and Topcu, G. and Laouer, H. and Akkal, S. and Boulebd, H (2025) 'LC-HRESIMS-Guided Phytochemical Characterization and Bioactivity Evaluation of Filipendula hexapetala Gilib. From Algeria: Antioxidant and Anticholinesterase Potential', Chemistry and Biodiversity, 22(11), pp. e01270. doi:10.1002/cbdv.202501270 Preclinical
https://doi.org/10.1002/cbdv.202501270 - Fandakli, S. and Korkmaz, B. and Faiz, O. and Kilic, G. and Erik, I. and Terzioglu, S. and Yayli, N (2021) 'Chemical Variation, Antimicrobial, Nitric Oxide Scavenging Activities and Tyrosinase Inhibition of Essential Oils and Solvent Extracts from Filipendula vulgaris Moench Growing in Turkey', Iranian Journal of Pharmaceutical Research, 20(3), pp. 110-120. doi:10.22037/ijpr.2021.114302.14786 Preclinical
https://doi.org/10.22037/ijpr.2021.114302.14786 - Radulovic, N. and Misic, M. and Aleksic, J. and Dokovic, D. and Palic, R. and Stojanovic, G (2007) 'Antimicrobial synergism and antagonism of salicylaldehyde in Filipendula vulgaris essential oil', Fitoterapia, 78(7-8), pp. 565-570. doi:10.1016/j.fitote.2007.03.022 Preclinical
https://doi.org/10.1016/j.fitote.2007.03.022 - Pulito, C. and Korita, E. and Sacconi, A. and Valerio, M. and Casadei, L. and Lo Sardo, F. and Mori, F. and Ferraiuolo, M. and Grasso, G. and Maidecchi, A. and Lucci, J. and Sudol, M. and Muti, P. and Blandino, G. and Strano, S (2019) 'Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma', Journal of Experimental and Clinical Cancer Research, 38(1), pp. 349. doi:10.1186/s13046-019-1352-3 Preclinical
https://doi.org/10.1186/s13046-019-1352-3 - Shilova, I.V. and Suslov, N.I (2015) 'Nootropic effect of meadowsweet (Filipendula vulgaris) extracts', Bulletin of Experimental Biology and Medicine, 158(5), pp. 659-663. doi:10.1007/s10517-015-2841-9 Preclinical
https://doi.org/10.1007/s10517-015-2841-9 - Shilova, I.V. and Suslov, N.I. and Amelchenko, V.P (2015) 'Nootropic Effects of Filipendula vulgaris Moench Water Extract Fractions', Bulletin of Experimental Biology and Medicine, 159(3), pp. 376-379. doi:10.1007/s10517-015-2967-9 Preclinical
https://doi.org/10.1007/s10517-015-2967-9 - Vengerovsky, A.I. and Suslov, N.I. and Kaygorodsev, A.V (2011) 'Effect of meadowsweet (Filipendula vulgaris) extract on bioenergetics of the brain during experimental posthypoxic encephalopathy', Bulletin of Experimental Biology and Medicine, 151(4), pp. 421-424. doi:10.1007/s10517-011-1346-4 Preclinical
https://doi.org/10.1007/s10517-011-1346-4 - Vengerovskii, A.I. and Suslov, N.I. and Kaigorodtsev, A.V (2011) 'Correction of experimental anxiety behavior by meadowsweet (Filipendula vulgaris) extracts', Eksperimental'naia i Klinicheskaia Farmakologiia, 74(9), pp. 3-6. Preclinical
https://scholar.google.com/scholar?q=Correction%20of%20experimental%20anxiety%20behavior%20by%20meadowsweet%20%28Filipendula%20vulgaris%29%20extracts - Pukalskiene, M. and Slapsyte, G. and Dedonyte, V. and Lazutka, J.R. and Mierauskiene, J. and Venskutonis, P.R (2017) 'Genotoxicity and antioxidant activity of five Agrimonia and Filipendula species plant extracts evaluated by comet and micronucleus assays in human lymphocytes and Ames Salmonella/microsome test', Food and Chemical Toxicology, 113, pp. 303-313. doi:10.1016/j.fct.2017.12.031 Preclinical
https://doi.org/10.1016/j.fct.2017.12.031 - Mitchell, M.I. and Routledge, P.A (1978) 'Hemlock water dropwort poisoning - a review', Clinical Toxicology, 12(4), pp. 417-26. doi:10.3109/15563657809150012 Clinical study
https://doi.org/10.3109/15563657809150012
- Hammoodi, O.T., Alkhilani, M.A., Alhayani, W.A., Al-Nuaimy, W. and Tala'a, A.A (2024) 'Effects of Laurus nobilis Leaf Extract on Healing of Experimentally Induced Wounds in Rabbits', Veterinary Medicine International, 2024, pp. 2889480. doi:10.1155/2024/2889480 Preclinical
https://doi.org/10.1155/2024/2889480 - Caputo, L., Nazzaro, F., Souza, L.F., Aliberti, L., De Martino, L. and Fratianni, F (2017) 'Laurus nobilis: Composition of Essential Oil and Its Biological Activities', Molecules, 22(6), pp. 930. doi:10.3390/molecules22060930 Preclinical
https://doi.org/10.3390/molecules22060930 - Bourebaba, N., Kornicka-Garbowska, K., Marycz, K., Bourebaba, L. and Kowalczuk, A (2021) 'Laurus nobilis ethanolic extract attenuates hyperglycemia and hyperinsulinemia-induced insulin resistance in HepG2 cell line through the reduction of oxidative stress and improvement of mitochondrial biogenesis', Mitochondrion, 59, pp. 190-213. doi:10.1016/j.mito.2021.06.003 Preclinical
https://doi.org/10.1016/j.mito.2021.06.003 - Dobroslavic, E., Repajic, M., Dragovic-Uzelac, V. and Elez Garofulic, I (2022) 'Isolation of Laurus nobilis Leaf Polyphenols: A Review on Current Techniques and Future Perspectives', Foods, 11(2), pp. 235. doi:10.3390/foods11020235 Meta-analysis / review
https://doi.org/10.3390/foods11020235 - Chbili, C., Maoua, M., Zaouali, M., Selmi, M., Kacem, I. and Mrizek, N (2022) 'Evaluation of daily Laurus nobilis tea consumption on anxiety and stress biomarkers in healthy volunteers', Archives Italiennes de Biologie, 160(3-4), pp. 136-146. doi:10.12871/000398292022343 Clinical study
https://doi.org/10.12871/000398292022343 - Chbili, C., Maoua, M., Selmi, M., Mrad, S., Khairi, H. and Limem, K (2020) 'Evaluation of Daily Laurus nobilis Tea Consumption on Lipid Profile Biomarkers in Healthy Volunteers', Journal of the American College of Nutrition, 39(8), pp. 733-738. doi:10.1080/07315724.2020.1727787 Clinical study
https://doi.org/10.1080/07315724.2020.1727787 - Bouadid, I., Amssayef, A. and Eddouks, M (2023) 'Study of the Antihypertensive Effect of Laurus nobilis in Rats', Cardiovascular & Hematological Agents in Medicinal Chemistry, 21(1), pp. 42-54. doi:10.2174/1871525720666220512154041 Preclinical
https://doi.org/10.2174/1871525720666220512154041 - Mohammed, R.R., Omer, A.K., Yener, Z., Uyar, A. and Ahmed, A.K (2020) 'Biomedical effects of Laurus nobilis L. leaf extract on vital organs in streptozotocin-induced diabetic rats: Experimental research', Annals of Medicine and Surgery, 61, pp. 188-197. doi:10.1016/j.amsu.2020.11.051 Preclinical
https://doi.org/10.1016/j.amsu.2020.11.051 - Uchiyama, N., Matsunaga, K., Kiuchi, F., Honda, G., Tsubouchi, A. and Nakajima-Shimada, J (2002) 'Trypanocidal terpenoids from Laurus nobilis L', Chemical & Pharmaceutical Bulletin, 50(11), pp. 1514-1516. doi:10.1248/cpb.50.1514 Preclinical
https://doi.org/10.1248/cpb.50.1514 - Saab, A.M., Guerrini, A., Zeino, M., Wiench, B., Rossi, D. and Gambari, R (2015) 'Laurus nobilis L. Seed Extract Reveals Collateral Sensitivity in Multidrug-Resistant P-Glycoprotein-Expressing Tumor Cells', Nutrition and Cancer, 67(4), pp. 664-675. doi:10.1080/01635581.2015.1019632 Preclinical
https://doi.org/10.1080/01635581.2015.1019632 - Elansary HO, et al. Laurus nobilis: Composition of Essential Oil and Its Biological Activities. Biomolecules. 2018;8 (2018) ';8(3):98', 8(3). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6152719/ Traditional / reference
https://pmc.ncbi.nlm.nih.gov/articles/PMC6152719/ - Fernandes F, et al. Laurus nobilis Leaves and Fruits: A Review of Metabolite Composition and Interest in Human Health. Applied Sciences. 2023;13 (2023) ';13(7):4606', 13(7). Available at: https://www.mdpi.com/2076-3417/13/7/4606 Traditional / reference
https://www.mdpi.com/2076-3417/13/7/4606 - Ramos C, et al. Bay Leaf. In: Nonvitamin and Nonmineral Nutritional Supplements. Academic Press; 2019:269-276. https://pmc.ncbi.nlm.nih.gov/articles/PMC7152419/ (2019) ':269-276'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7152419/ Traditional / reference
https://pmc.ncbi.nlm.nih.gov/articles/PMC7152419/ - Singletary KW. Bay Leaf: Potential Health Benefits. Nutrition Today. 2021;55 (2021) ';55(4):184-193', 55(4). Available at: https://journals.lww.com/nutritiontodayonline/fulltext/2021/07000/bay_leaf__potential_health_benefits.8.aspx Traditional / reference
https://journals.lww.com/nutritiontodayonline/fulltext/2021/07000/bay_leaf__potential_health_benefits.8.aspx - University of Arizona Campus Arboretum. Medicinal Plant Virtual Tour - Bay Laurel. https://arboretum.arizona.edu/medicinal-plant-virtual-tour-bay-laurel. Available at: https://arboretum.arizona.edu/medicinal-plant-virtual-tour-bay-laurel Traditional / reference
https://arboretum.arizona.edu/medicinal-plant-virtual-tour-bay-laurel - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Malaspina, P. and Betuzzi, F. and Ingegneri, M. and Smeriglio, A. and Cornara, L. and Trombetta, D (2022) 'Risk of Poisoning from Garden Plants: Misidentification between Laurel and Cherry Laurel', Toxins, 14(11), pp. 726. doi:10.3390/toxins14110726 Preclinical
https://doi.org/10.3390/toxins14110726 - Henriet, M. and Auquiere, J.P. and Moens, P (1974) 'Analysis and content of hydrocyanic acid by cutting, row and organographic zone of leaves of cherry laurel (Prunus laurocerasus L)', Journal de Pharmacie de Belgique, 29(5), pp. 437-43. Available at: https://pubmed.ncbi.nlm.nih.gov/4377277/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/4377277/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.