Plant Comparison
Meadowsweet vs Figwort
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Meadowsweet and Figwort: they share 8 indicated uses (arthritis / joint pain, inflammation (general), menstrual cramps, …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Meadowsweet | Figwort | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 2/10 | Comparable evidence |
| Menstrual cramps | 1/10 | 1/10 | Comparable evidence |
| Muscle spasm | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 2/10 | Comparable evidence |
| Swelling / fluid retention | 1/10 | 1/10 | Comparable evidence |
| Urinary support | 1/10 | 1/10 | Comparable evidence |
| Urinary tract infection (UTI) | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Historically the source of aspirin's chemical inspiration; provide the plant's analgesic and anti-inflammatory activity, buffered by co-occurring mucilage and tannins.
Antioxidant constituents contributing to the plant's anti-inflammatory and gastroprotective effects.
Contribute to astringency and the characteristic sweet almond-like fragrance.
Anti-inflammatory constituents; harpagoside also has cardiac (inotropic) activity.
Supporting antioxidant constituents.
Pharmacological Actions
Mild diuretic and lymphatic 'detoxifying' herb (traditional); Traditional 'alterative' for chronic skin conditions - eczema, psoriasis, rashes (as a poultice, salve or tea)
Antispasmodic / smooth-muscle relaxant (preclinical - an extract relaxed isolated intestinal smooth muscle, apparently via muscarinic receptors)
Mild diuretic and lymphatic 'detoxifying' herb (traditional)
Traditional & Indicated Uses
inferred from gastroprotective action
inferred from anti-inflammatory action
inferred from anticancer action
inferred from gastroprotective action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
inferred from anti-inflammatory action
inferred from alterative action
Traditional 'alterative' for chronic skin conditions - eczema, psoriasis, rashes (as a poultice, salve or tea)
inferred from anti-inflammatory action
inferred from antispasmodic action
Traditional 'alterative' for chronic skin conditions - eczema, psoriasis, rashes (as a poultice, salve or tea)
Anti-inflammatory; soothes inflamed, irritated skin; Traditional 'alterative' for chronic skin conditions - eczema, psoriasis, rashes (as a poultice, salve or tea)
inferred from diuretic action
inferred from diuretic action
Safety, Cautions & Contraindications
Generally safe in normal culinary and medicinal doses. Avoid in salicylate sensitivity or aspirin allergy. Not recommended for children with viral illnesses (Reye's syndrome risk, as with other salicylate-containing plants). Avoid during pregnancy and breastfeeding.
Duke (2002) rates meadowsweet as ++ and notes analgesic, antiulcer, antirheumatic, astringent, and anti-aggregant activities at the experimental level (score 1). The plant is historically significant as a precursor to aspirin — salicylate compounds in meadowsweet were originally used to derive acetylsalicylic acid. Unlike aspirin, meadowsweet's salicylates are combined with protective mucilaginous compounds that may reduce gastric irritation. Duke notes that individuals with aspirin (salicylate) sensitivity should avoid meadowsweet; the plant also has anticoagulant properties that may interact with blood-thinning medications (Duke, 2002).
Avoid if you have a heart condition or take cardiac medicines: figwort's harpagoside has a stimulating (inotropic) effect on the heart, so it is traditionally avoided with rapid heartbeat or heart disease.
Avoid during pregnancy. There is insufficient reliable evidence on the safety of taking figwort by mouth, so internal use should be cautious and short-term.
External Ids
Botanical Description
Tall, moisture-loving perennial herb with pinnately compound leaves, dark green above and whitish-downy beneath, the leaflets sharply toothed. Dense, fluffy, creamy-white flower clusters with a strong, sweet, almond-like fragrance are borne atop reddish, grooved stems.[1]
Tall perennial herb (Scrophulariaceae), 50-100 cm (occasionally more), with a distinctly square stem. Leaves are opposite, ovate, toothed and unpleasant-smelling. Small, dull maroon-brown, two-lipped flowers are borne in loose, branched clusters (cymes), followed by small dry seed capsules.[11]
Habitat
Harvesting
The flowering tops, leaf and stem are cut in summer as the flowers open, when the characteristic salicylate content is highest, and dried in a warm, shaded, airy place.[1]
Aerial parts are cut during flowering (summer); the root can also be dug in autumn.[11]
Traditional Uses
Meadowsweet is historically significant as the plant from which salicylic acid derivatives (the chemical basis of aspirin) were first isolated, and has long been used in European folk medicine as an anti-inflammatory, analgesic and gastroprotective remedy for feverish colds, rheumatic and joint pain, and digestive complaints such as acid reflux and indigestion - notably, its natural mucilage is thought to buffer the gastric irritation associated with isolated salicylates.[1, 4]
Figwort takes one common name, 'scrofula plant', from its historic traditional use for scrofula (tuberculous lymph-node swelling) under the Doctrine of Signatures, its knotty root resembling swollen glands. It has a long folk-medicine reputation as an 'alterative' (blood-purifying) herb for chronic skin conditions such as eczema and psoriasis, applied as a poultice, salve or tea.[11, 12]
Preparations
Dried flower, leaf and stem infused in hot water as a traditional anti-inflammatory and digestive tea.
Tincture (1:5) of the dried aerial parts; single dose 2-4 ml, daily dose 6-12 ml per the EU herbal monograph. Educational reference only, not a prescription.
Concentrated extract studied in vitro and in vivo for anti-inflammatory and gastroprotective activity.
Dosage
The EU herbal monograph gives a single dose of 1.5-6 g of the comminuted herb as an infusion, for a daily dose of 2-18 g, in adults and elderly; a powdered herbal substance at 250-500 mg per dose (250-1500 mg daily) and a 1:5 tincture at 2-4 mL per dose (6-12 mL daily) are also listed. Contraindicated in hypersensitivity to salicylates. For rheumatic-type complaints, not to be used for more than 4 weeks. Not recommended under 18 years. Educational reference only, not a prescription.
Traditional guidance suggests roughly 2-4 g dried herb per cup as an infusion, taken cautiously and short-term given limited safety data and the cardioactive harpagoside content. Educational reference only, not a prescription; avoid with heart conditions/cardiac medicines and in pregnancy.
References
Lookalikes Review
Dangerous Lookalikes
Not documented
References & Sources
- Samardžić, S., Arsenijević, J., Božić, D., Milenković, M. et al (2017) 'Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench', Journal of Ethnopharmacology, 213, pp. 132-137. doi:10.1016/j.jep.2017.11.013 Preclinical
https://doi.org/10.1016/j.jep.2017.11.013 - Andonova, T., Muhovski, Y., Apostolova, E., Naimov, S. et al (2024) 'DNA-Protective, Antioxidant and Anti-Carcinogenic Potential of Meadowsweet (Filipendula ulmaria) Dry Tincture', Antioxidants (Basel), 13(10), pp. 1200. doi:10.3390/antiox13101200 Preclinical
https://doi.org/10.3390/antiox13101200 - Van der Auwera, A., Peeters, L., Foubert, K., Piazza, S. et al (2023) 'In Vitro Biotransformation and Anti-Inflammatory Activity of Constituents and Metabolites of Filipendula ulmaria', Pharmaceutics, 15(4), pp. 1291. doi:10.3390/pharmaceutics15041291 Preclinical
https://doi.org/10.3390/pharmaceutics15041291 - Katanic, J., Boroja, T., Mihailovic, V., Nikles, S., Pan, S., Rosic, G., Selakovic, D., Joksimovic, J., Mitrovic, S. and Bauer, R (2016) 'In vitro and in vivo assessment of meadowsweet (Filipendula ulmaria) as anti-inflammatory agent', Journal of Ethnopharmacology, 193, pp. 627-636. doi:10.1016/j.jep.2016.10.015 Preclinical
https://doi.org/10.1016/j.jep.2016.10.015 - Samardzic, S., Tomic, M., Pecikoza, U., Stepanovic-Petrovic, R. and Maksimovic, Z (2016) 'Antihyperalgesic activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench in a rat model of inflammation', Journal of Ethnopharmacology, 193, pp. 652-656. doi:10.1016/j.jep.2016.10.024 Preclinical
https://doi.org/10.1016/j.jep.2016.10.024 - Katanic, J., Matic, S., Pferschy-Wenzig, E., Kretschmer, N., Boroja, T., Mihailovic, V., Stankovic, V., Stankovic, N., Mladenovic, M., Stanic, S., Mihailovic, M. and Bauer, R (2016) 'Filipendula ulmaria extracts attenuate cisplatin-induced liver and kidney oxidative stress in rats: In vivo investigation and LC-MS analysis', Food and Chemical Toxicology, 99, pp. 86-102. doi:10.1016/j.fct.2016.11.018 Preclinical
https://doi.org/10.1016/j.fct.2016.11.018 - Arsenijevic, N., Selakovic, D., Katanic Stankovic, J.S., Mihailovic, V., Mitrovic, S., Milenkovic, J., Milanovic, P., Vasovic, M., Nikezic, A., Milosevic-Djordjevic, O., Zivanovic, M., Filipovic, N., Jakovljevic, V., Jovicic, N. and Rosic, G (2021) 'Variable neuroprotective role of Filipendula ulmaria extract in rat hippocampus', Journal of Integrative Neuroscience, 20(4), pp. 871-883. doi:10.31083/j.jin2004089 Preclinical
https://doi.org/10.31083/j.jin2004089 - Matic, S., Katanic, J., Stanic, S., Mladenovic, M., Stankovic, N., Mihailovic, V. and Boroja, T (2015) 'In vitro and in vivo assessment of the genotoxicity and antigenotoxicity of the Filipendula hexapetala and Filipendula ulmaria methanol extracts', Journal of Ethnopharmacology, 174, pp. 287-292. doi:10.1016/j.jep.2015.08.025 Preclinical
https://doi.org/10.1016/j.jep.2015.08.025 - Pannakal, S.T., Eilstein, J., Hubert, J., Kotland, A., Prasad, A., Gueguiniat-Prevot, A., Juchaux, F., Beaumard, F., Seru, G., John, S. and Roy, D (2023) 'Rapid Chemical Profiling of Filipendula ulmaria Using CPC Fractionation, 2-D Mapping of 13C NMR Data, and High-Resolution LC-MS', Molecules, 28(17), pp. 6349. doi:10.3390/molecules28176349 Preclinical
https://doi.org/10.3390/molecules28176349 - Valle, M.G., Nano, G.M. and Tira, S (1988) 'The Essential Oil of Filipendula ulmaria', Planta Medica, 54(2), pp. 181-182. doi:10.1055/s-2006-962390 Preclinical
https://doi.org/10.1055/s-2006-962390 - Popowski, D., Zentek, J., Piwowarski, J.P. and Granica, S (2021) 'Gut Microbiota of Pigs Metabolizes Extracts of Filipendula ulmaria and Orthosiphon aristatus - Herbal Remedies Used in Urinary Tract Disorders', Planta Medica, 88(3-04), pp. 254-261. doi:10.1055/a-1647-2866 Preclinical
https://doi.org/10.1055/a-1647-2866 - Bespalov, V.G., Alexandrov, V.A., Semenov, A.L., Kovan'ko, E.G., Ivanov, S.D., Vysochina, G.I., Kostikova, V.A. and Baranenko, D.A (2016) 'The inhibitory effect of meadowsweet (Filipendula ulmaria) on radiation-induced carcinogenesis in rats', International Journal of Radiation Biology, 93(4), pp. 394-401. doi:10.1080/09553002.2016.1257834 Preclinical
https://doi.org/10.1080/09553002.2016.1257834 - European Medicines Agency (HMPC) (2011) 'Community herbal monograph on Filipendula ulmaria (L.) Maxim., herba'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-filipendula-ulmaria-l-maxim-herba-first-version_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-filipendula-ulmaria-l-maxim-herba-first-version_en.pdf - Bridge, J (2008) 'The Herbal Remedy Handbook'. Traditional / reference
https://scholar.google.com/scholar?q=The%20Herbal%20Remedy%20Handbook - Drummond, E.M., Harbourne, N., Marete, E., Jacquier, J.C., O'Riordan, D. and Gibney, E.R (2013) 'Inhibition of pro-inflammatory biomarkers in THP1 macrophages by polyphenols derived from chamomile, meadowsweet and willow bark', 27(4), pp. 588--594. Traditional / reference
https://scholar.google.com/scholar?q=Inhibition%20of%20pro-inflammatory%20biomarkers%20in%20THP1%20macrophages%20by%20polyphenols%20derived%20from%20chamomile%2C%20meadowsweet%20and%20willow%20bark - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
- Stevenson, P.C., Simmonds, M.S.J., Sampson, J., Houghton, P.J. and Grice, P (2002) 'Wound healing activity of acylated iridoid glycosides from Scrophularia nodosa', Phytotherapy Research, 16(1), pp. 33-35. doi:10.1002/ptr.798 Preclinical
https://doi.org/10.1002/ptr.798 - Ahmad, M., Muhammad, N., Mehjabeen, Jahan, N. and others (2012) 'Biological screening of Scrophularia nodosa extract and its fractions', Pakistan Journal of Pharmaceutical Sciences, 25(2), pp. 307-313. Preclinical
https://scholar.google.com/scholar?q=Biological%20screening%20of%20Scrophularia%20nodosa%20extract%20and%20its%20fractions - Miyase, T. and Mimatsu, A (1999) 'Acylated iridoid and phenylethanoid glycosides from the aerial parts of Scrophularia nodosa', Journal of Natural Products, 62(8), pp. 1079-1084. doi:10.1021/np9805746 Preclinical
https://doi.org/10.1021/np9805746 - Sesterhenn, K., Distl, M. and Wink, M (2006) 'Occurrence of iridoid glycosides in in vitro cultures and intact plants of Scrophularia nodosa L', Plant Cell Reports, 26(3), pp. 365-371. doi:10.1007/s00299-006-0233-3 Preclinical
https://doi.org/10.1007/s00299-006-0233-3 - Soualeh, N., Stiévenard, A., Baudelaire, E., Bouayed, J. and Soulimani, R (2019) 'Powders with small microparticle size from Hedera helix and Scrophularia nodosa exhibited high preventive antioxidant activity against H2O2-induced oxidative stress in mouse primary spleen cells', International Journal for Vitamin and Nutrition Research, 88(3-4), pp. 208-218. doi:10.1024/0300-9831/a000526 Preclinical
https://doi.org/10.1024/0300-9831/a000526 - Papp, N., Czégényi, D., Tóth, M., Dénes, T. and others (2022) 'Ethnomedicine survey on folk dermatology in Transylvania, Romania', Clinics in Dermatology, 40(6), pp. 651-664. doi:10.1016/j.clindermatol.2022.07.013 Traditional / reference
https://doi.org/10.1016/j.clindermatol.2022.07.013 - Soulimani, R., Dicko, A., Baudelaire, E. and Bouayed, J (2021) 'Increased anti-inflammatory activity and enhanced phytochemical concentrations in superfine powders obtained by controlled differential sieving process from four medicinal plants', International Journal for Vitamin and Nutrition Research, 93(4), pp. 339-351. doi:10.1024/0300-9831/a000739 Preclinical
https://doi.org/10.1024/0300-9831/a000739 - Ohiienko, T., Kutsyk, R., Kurovets, L., Ohiienko, S. and others (2023) 'Screening of medicinal and aromatic plants extracts for the synergism with fluconazole against Candida albicans and Candida tropicalis fungi associated with denture stomatitis', Wiadomosci Lekarskie, 76(7), pp. 1615-1620. doi:10.36740/WLek202307115 Preclinical
https://doi.org/10.36740/WLek202307115 - Leclerc, H (1949) '[The scrofular, Scrophularia nodosa L.]', Revue de Phytotherapie, 13(87), pp. 381-383. Traditional / reference
https://scholar.google.com/scholar?q=%5BThe%20scrofular%2C%20Scrophularia%20nodosa%20L.%5D - Akerreta, S., Cavero, R.Y. and Calvo, M.I (2007) 'First comprehensive contribution to medical ethnobotany of Western Pyrenees', Journal of Ethnobiology and Ethnomedicine, 3, pp. 26. doi:10.1186/1746-4269-3-26 Traditional / reference
https://doi.org/10.1186/1746-4269-3-26 - Medicinal Herbals (n.d.) 'Figwort (Scrophularia nodosa): The Natural Skin Healer'. Available at: https://medicinalherbals.net/figwort-scrophularia-nodosa-natural-skin-healer/ Traditional / reference
https://medicinalherbals.net/figwort-scrophularia-nodosa-natural-skin-healer/ - WebMD (n.d.) 'Figwort: Overview, Uses, Side Effects, Precautions, Interactions'. Available at: https://www.webmd.com/vitamins/ai/ingredientmono-446/figwort Traditional / reference
https://www.webmd.com/vitamins/ai/ingredientmono-446/figwort - Ahmad, M., Muhammad, N., Mehjabeen, Jahan, N., Ahmad, M., Obaidullah, Qureshi, M. and Jan, S.U (2012) 'Spasmolytic effects of Scrophularia nodosa extract on isolated rabbit intestine', Pakistan Journal of Pharmaceutical Sciences, 25(1), pp. 267--275. Traditional / reference
https://scholar.google.com/scholar?q=Spasmolytic%20effects%20of%20Scrophularia%20nodosa%20extract%20on%20isolated%20rabbit%20intestine - First Nature 'Scrophularia nodosa, Common Figwort'. Available at: https://www.first-nature.com/flowers/scrophularia-nodosa.php Traditional / reference
https://www.first-nature.com/flowers/scrophularia-nodosa.php - Berdai, M.A. and Labib, S. and Chetouani, K. and Harandou, M (2012) 'Atropa belladonna intoxication: a case report', Pan African Medical Journal, 11, pp. 72. Available at: https://pubmed.ncbi.nlm.nih.gov/22655106/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/22655106/ - Oerlemans, C. and de Vries, I. and van Riel, A.J.H.P (2017) 'Anticholinergic syndrome caused by contaminated herbal tea; acting swiftly to identify the source', Nederlands Tijdschrift voor Geneeskunde, 161, pp. D1261. Available at: https://pubmed.ncbi.nlm.nih.gov/28612694/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/28612694/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.