Plant Comparison
Eyebright vs Sweet Violet
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Eyebright and Sweet Violet: they share 6 indicated uses (arthritis / joint pain, cancer (anticancer research), cough, …); 2 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Eyebright | Sweet Violet | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Cancer (anticancer research) | 2/10 | 2/10 | Comparable evidence |
| Cough | 1/10 | 5/10 | Stronger for Sweet Violet |
| Inflammation (general) | 2/10 | 1/10 | Comparable evidence |
| Respiratory support | 1/10 | 6/10 | Stronger for Sweet Violet |
| Skin irritation | 1/10 | 5/10 | Stronger for Sweet Violet |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Give the plant its anti-inflammatory action on irritated tissue.
Pharmacological Actions
Astringent and anti-inflammatory for eye irritation, redness and conjunctivitis (traditional, as an eye compress or bath) - an open prospective cohort of Euphrasia single-dose eye drops reported recovery or clear improvement in most patients with conjunctivitis
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
Traditional & Indicated Uses
Eases eye strain and watery, itchy eyes from allergy (hay fever / allergic conjunctivitis)
inferred from anti-inflammatory action
inferred from anticancer action
Soothes upper-respiratory catarrh and mild infection (traditional)
Astringent and anti-inflammatory for eye irritation, redness and conjunctivitis (traditional, as an eye compress or bath) - an open prospective cohort of Euphrasia single-dose eye drops reported recovery or clear improvement in most patients with conjunctivitis; Eases eye strain and watery, itchy eyes from allergy (hay fever / allergic conjunctivitis)
Eases eye strain and watery, itchy eyes from allergy (hay fever / allergic conjunctivitis)
Soothes upper-respiratory catarrh and mild infection (traditional)
inferred from anti-inflammatory action
Soothes upper-respiratory catarrh and mild infection (traditional)
inferred from anti-inflammatory action
inferred from anti-inflammatory action
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
inferred from anticancer action
Demulcent / expectorant for cough, bronchitis and catarrh (mucilage soothes; saponins loosen mucus) - a double-blind RCT found violet-flower syrup, added to standard treatment, sped cough suppression in children with asthma
Mild sedative for sleeplessness and to ease headache (traditional)
inferred from anti-inflammatory action
Mild sedative for sleeplessness and to ease headache (traditional)
inferred from expectorant action
inferred from demulcent action
Safety, Cautions & Contraindications
CRITICAL: do not put non-sterile, homemade eyebright preparations directly into the eye - this risks serious eye infection. Use only commercially prepared sterile products in the eye, or apply a strained, cooled infusion as a compress over closed eyelids.
Traditional use only; persistent eye symptoms, pain, discharge or vision change need assessment by an eye-care professional. Safety in pregnancy and breastfeeding is not established.
Generally well tolerated as flower/leaf preparations. It contains salicylates, so use caution if you are salicylate-sensitive; the root in large doses is emetic and purgative.
Safety in pregnancy and breastfeeding is not established, so avoid medicinal doses.
External Ids
Botanical Description
Small, semi-parasitic annual herb (drawing some nutrients from the roots of neighbouring grasses) with tiny, opposite, toothed leaves and delicate, two-lipped white to pale lilac flowers marked with purple veins and a yellow throat spot, giving a bright, eye-like appearance that inspired both its common and Latin names.[11]
Low, spreading perennial herb with heart-shaped, softly toothed leaves arising from a short rootstock, spreading by runners (stolons). Fragrant, deep violet-purple (occasionally white) flowers with five petals, the lower petal spurred, are borne singly on slender stalks.[11]
Habitat
Grows in short, unimproved grassland, pastures, meadows and dunes on well-drained soils, always in association with grasses on which it partially parasitises; native to Europe.[11]
Grows in woodland edges, hedgerows, shaded banks and gardens on moist, humus-rich soils; native to Europe, North Africa and Asia and widely naturalised and cultivated elsewhere.[11]
Harvesting
The flowering aerial parts are cut in summer while in flower and dried in a warm, shaded, airy place.[11]
Flowers are picked as they open in early spring; leaves can be gathered through the growing season and dried.[11]
Traditional Uses
Sweet violet flower and leaf have a long European folk history as a soothing demulcent and expectorant remedy for cough, bronchitis and catarrh, and as a mild sedative for sleeplessness and headache; the flower syrup in particular has a long tradition as a children's cough remedy.[11]
Preparations
Strained, cooled infusion applied as a compress over closed eyelids, or used (only when sterile, commercially prepared) as an eyewash for irritated or red eyes.
Commercially prepared, sterile Euphrasia eye drops used for conjunctivitis; a prospective clinical cohort found improvement in most users.
Dosage
No dose is given here because no official posology exists. The HMPC assessed eyebright and DECLINED to establish a herbal monograph, concluding that the efficacy of the claimed uses is undocumented and that external eye application of ex tempore (home-prepared) preparations is 'not hygienic and not safe', so therapeutic use cannot be recommended. Traditional sources describe a strained, cooled infusion used as a compress, but that is precisely the practice the HMPC advised against; nothing home-prepared should be put in or on the eye. Educational reference only, not a prescription.
A double-blind randomised placebo-controlled trial used 5 mL of Viola odorata syrup every 12 hours for 4 weeks as add-on therapy for insomnia. Traditional references suggest around 2-4 g of dried flower and leaf per cup, up to three times daily. Note the EU monograph on Violae herba cum flore covers Viola tricolor, a different species, and its posology does not transfer here. Educational reference only, not a prescription.
References
Lookalikes Review
Drug Class Interactions
Not documented
Dangerous Lookalikes
Not documented
References & Sources
- Novy, P., Davidova, H., Serrano-Rojero, C.S., Rondevaldova, J. et al (2015) 'Composition and Antimicrobial Activity of Euphrasia rostkoviana Hayne Essential Oil', Evidence-Based Complementary and Alternative Medicine, 2015, pp. 734101. doi:10.1155/2015/734101 Preclinical
https://doi.org/10.1155/2015/734101 - D'Ambrosio, M., Ciocarlan, A. and Aricu, A (2020) 'Minor acetylated metabolites from Euphrasia rostkoviana', Natural Product Research, 34(2), pp. 290-295. doi:10.1080/14786419.2018.1530227 Preclinical
https://doi.org/10.1080/14786419.2018.1530227 - Ververis, A., Kyriakou, S., Paraskeva, H., Panayiotidis, M.I. et al (2024) 'Chemical Characterization and Assessment of the Neuroprotective Potential of Euphrasia officinalis', International Journal of Molecular Sciences, 25(23), pp. 12902. doi:10.3390/ijms252312902 Preclinical
https://doi.org/10.3390/ijms252312902 - Meier-Girard, D., Gerstenberg, G., Stoffel, L., Kohler, T., Klein, S.D., Eschenmoser, M., Mitter, V.R., Nelle, M. and Wolf, U (2020) 'Euphrasia eye drops in preterm neonates with ocular discharge: a randomized double-blind placebo-controlled trial', Frontiers in Pediatrics, 8, pp. 449. doi:10.3389/fped.2020.00449 Randomized trial
https://doi.org/10.3389/fped.2020.00449 - Liu, Y., Hwang, E., Ngo, H.T.T., Perumalsamy, H., Kim, Y.J., Li, L. and Yi, T.H (2018) 'Protective effects of Euphrasia officinalis extract against ultraviolet B-induced photoaging in normal human dermal fibroblasts', International Journal of Molecular Sciences, 19(11), pp. 3327. doi:10.3390/ijms19113327 Preclinical
https://doi.org/10.3390/ijms19113327 - Porchezhian, E., Ansari, S.H. and Shreedharan, N.K (2000) 'Antihyperglycemic activity of Euphrasia officinale leaves', Fitoterapia, 71(5), pp. 522-526. doi:10.1016/s0367-326x(00)00204-5 Preclinical
https://doi.org/10.1016/s0367-326x(00)00204-5 - Sticher, O. and Salama, O (1981) 'Iridoid glucosides from Euphrasia rostkoviana', Planta Medica, 42(6), pp. 122-123. doi:10.1055/s-2007-971584 Preclinical
https://doi.org/10.1055/s-2007-971584 - Lorenz, P., Knittel, D.N., Conrad, J., Lotter, E.M., Heilmann, J., Stintzing, F.C. and Kammerer, D.R (2016) '1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: lipid compounds from Euphrasia rostkoviana Hayne and E. tetraquetra (Breb.) Arrond', Chemistry & Biodiversity, 13(5), pp. 602-612. doi:10.1002/cbdv.201500233 Preclinical
https://doi.org/10.1002/cbdv.201500233 - Gawenda-Kempczynska, D., Olech, M., Balcerek, M., Nowak, R., Zaluski, T. and Zaluski, D (2022) 'Phenolic acids as chemotaxonomic markers able to differentiate the Euphrasia species', Phytochemistry, 203, pp. 113342. doi:10.1016/j.phytochem.2022.113342 Preclinical
https://doi.org/10.1016/j.phytochem.2022.113342 - Benedec, D., Oniga, I., Hanganu, D., Vlase, A.M., Ielciu, I., Crisan, G., Fit, N., Niculae, M., Bab, T., Pall, E. and Vlase, L (2024) 'Revealing the Phenolic Composition and the Antioxidant, Antimicrobial and Antiproliferative Activities of Two Euphrasia sp. Extracts', Plants, 13(13), pp. 1790. doi:10.3390/plants13131790 Preclinical
https://doi.org/10.3390/plants13131790 - Herbal Reality (n.d.) 'Eyebright (Euphrasia officinalis): Benefits, Uses, Safety'. Available at: https://www.herbalreality.com/herb/eyebright/ Traditional / reference
https://www.herbalreality.com/herb/eyebright/ - Paduch, R. and colleagues (2014) 'Assessment of Eyebright (Euphrasia officinalis L.) Extract Activity in Relation to Human Corneal Cells Using In Vitro Tests'. doi:10.5152/balkanmedj.2014.8377 Traditional / reference
https://doi.org/10.5152/balkanmedj.2014.8377 - Stoss, M., Michels, C., Peter, E., Beutke, R. and Gorter, R.W (2000) 'Prospective cohort trial of Euphrasia single-dose eye drops in conjunctivitis', Journal of Alternative and Complementary Medicine, 6(6), pp. 499--508. doi:10.1089/acm.2000.6.499 Clinical study
https://doi.org/10.1089/acm.2000.6.499 - European Medicines Agency (HMPC) (2010) 'Public statement on Euphrasia officinalis L. and Euphrasia rostkoviana Hayne, herba'. Available at: https://www.ema.europa.eu/en/documents/herbal-report/final-public-statement-euphrasia-officinalis-l-and-euphrasia-rostkoviana-hayne-herba_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-report/final-public-statement-euphrasia-officinalis-l-and-euphrasia-rostkoviana-hayne-herba_en.pdf
- Feyzabadi, Z., Ghorbani, F., Vazani, Y. and Zarshenas, M.M (2017) 'A Critical Review on Phytochemistry, Pharmacology of Viola odorata L. and Related Multipotential Products in Traditional Persian Medicine', Phytotherapy Research, 31(11), pp. 1669-1675. doi:10.1002/ptr.5909 Meta-analysis / review
https://doi.org/10.1002/ptr.5909 - Heger, T., Zatloukal, M., Kubala, M., Strnad, M. and others (2022) 'Procyanidin C1 from Viola odorata L. inhibits Na,K-ATPase', Scientific Reports, 12(1), pp. 7011. doi:10.1038/s41598-022-11086-y Preclinical
https://doi.org/10.1038/s41598-022-11086-y - Yousefnia, S., Naseri, D., Seyed Forootan, F., Tabatabaeian, M. and others (2020) 'Suppressive role of Viola odorata extract on malignant characters of mammosphere-derived breast cancer stem cells', Clinical & Translational Oncology, 22(9), pp. 1619-1634. doi:10.1007/s12094-020-02307-9 Preclinical
https://doi.org/10.1007/s12094-020-02307-9 - Tafazoli, V., Shahriari, M., Heydari, M., Nikbakht, H.A. and others (2020) 'The Effect of Viola odorata L. Oil for Fever in Children: A Randomized Triple-blinded Placebo-controlled Clinical Trial', Current Drug Discovery Technologies, 17(5), pp. 696-703. doi:10.2174/1570163816666190620142256 Randomized trial
https://doi.org/10.2174/1570163816666190620142256 - Rahimi, V.B., Askari, V.R., Emami, S.A. and Tayarani-Najaran, Z (2017) 'Anti-melanogenic activity of Viola odorata different extracts on B16F10 murine melanoma cells', Iranian Journal of Basic Medical Sciences, 20(3), pp. 242-249. doi:10.22038/ijbms.2017.8350 Preclinical
https://doi.org/10.22038/ijbms.2017.8350 - Adel Mehraban, M.S., Shirzad, M., Mohammad Taghizadeh Kashani, L., Ahmadian-Attari, M.M. and others (2022) 'Efficacy and safety of add-on Viola odorata L. in the treatment of COVID-19: A randomized double-blind controlled trial', Journal of Ethnopharmacology, 304, pp. 116058. doi:10.1016/j.jep.2022.116058 Randomized trial
https://doi.org/10.1016/j.jep.2022.116058 - Saleem, U., Hira, S., Anwar, F., Shah, M.A. and others (2021) 'Pharmacological Screening of Viola odorata L. for Memory-Enhancing Effect via Modulation of Oxidative Stress and Inflammatory Biomarkers', Frontiers in Pharmacology, 12, pp. 664832. doi:10.3389/fphar.2021.664832 Preclinical
https://doi.org/10.3389/fphar.2021.664832 - Shayesteh, M., Vaez-Mahdavi, M.R., Shams, J., Kamalinejad, M. and others (2020) 'Effects of Viola odorata as an Add-On Therapy on Insomnia in Patients with Obsession or Depression: A Pilot Randomized Double-Blind Placebo-Controlled Trial', Journal of Alternative and Complementary Medicine, 26(5), pp. 398-408. doi:10.1089/acm.2019.0254 Randomized trial
https://doi.org/10.1089/acm.2019.0254 - Feyzabadi, Z., Jafari, F., Kamali, S.H., Ashayeri, H. and others (2014) 'Efficacy of Viola odorata in Treatment of Chronic Insomnia', Iranian Red Crescent Medical Journal, 16(12), pp. e17511. doi:10.5812/ircmj.17511 Clinical study
https://doi.org/10.5812/ircmj.17511 - Parsley, N.C., Kirkpatrick, C.L., Crittenden, C.M., Rad, J.G. and others (2018) 'PepSAVI-MS reveals anticancer and antifungal cycloviolacins in Viola odorata', Phytochemistry, 152, pp. 61-70. doi:10.1016/j.phytochem.2018.04.014 Preclinical
https://doi.org/10.1016/j.phytochem.2018.04.014 - Herbal Reality (n.d.) 'Violets (Viola odorata): Benefits, Safety, Uses'. Available at: https://www.herbalreality.com/herb/violets/ Traditional / reference
https://www.herbalreality.com/herb/violets/ - Qasemzadeh, M.J., Sharifi, H., Hamedanian, M., Gharehbeglou, M., Heydari, M., Sardari, M., Akhlaghdoust, M. and Minae, M.B (2015) 'The Effect of Viola odorata Flower Syrup on the Cough of Children With Asthma: A Double-Blind, Randomized Controlled Trial', Journal of Evidence-Based Complementary & Alternative Medicine, 20(4), pp. 287--291. doi:10.1177/2156587215584862 Randomized trial
https://doi.org/10.1177/2156587215584862 - RxList (n.d.) 'Sweet Violet: Health Benefits, Side Effects, Uses, Dose & Precautions'. Available at: https://www.rxlist.com/supplements/sweet_violet.htm Traditional / reference
https://www.rxlist.com/supplements/sweet_violet.htm - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003 - Unruly Gardening 'Foraging Violets: How to Identify, Harvest and Use'. Available at: https://unrulygardening.com/foraging-violets/ Traditional / reference
https://unrulygardening.com/foraging-violets/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.