Omnia SanaPlant Comparison
Cardamom vs Hop
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Cardamom and Hop: they share 5 indicated uses (arthritis / joint pain, bloating, indigestion, …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Cardamom | Hop | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Bloating | 1/10 | 1/10 | Comparable evidence |
| Indigestion | 1/10 | 1/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Seed essential oil dominated by 1,8-cineole and alpha-terpinyl acetate, giving the characteristic aroma and much of the carminative, antimicrobial and antioxidant activity.
Additional antioxidant constituents of the seed.
Alpha- and beta-bitter acids responsible for the characteristic bitterness and much of the sedative, GABA-A-receptor-active and antimicrobial activity.
Xanthohumol has antioxidant activity; 8-prenylnaringenin has notable phytoestrogenic activity, the basis of the mild oestrogenic caution.
Aromatic volatile oil contributing to the characteristic hop aroma.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from digestive action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from digestive action
inferred from anti-inflammatory action
inferred from sedative action
Safety, Cautions & Contraindications
Cardamom is generally considered safe for most people when used in culinary amounts. At medicinal doses (supplement form), rare side effects include mild gastrointestinal discomfort and allergic reactions. There are no well-documented serious drug interactions at culinary doses. Cardamom may mildly lower blood pressure — caution if combined with antihypertensive medications. Some sources suggest potential gallstone formation with very high doses, as cardamom may stimulate bile flow. Avoid therapeutic doses during pregnancy until more safety data are available; culinary use is considered safe. Allergy to other Zingiberaceae (ginger, turmeric) may indicate cross-reactivity risk (Korikanthimath and Hiremath, 2002).
Duke (2002) provides clinical support (score 2) for cardamom as a cholagogue, antiviral agent, and appetite stimulant. Commission E and the German PDR (PHR) approve it for loss of appetite and bronchitis (score 2). The essential oil shows antispasmodic and carminative activity. Dose: 1.5 g ground fruit or equivalent preparation three times daily. Duke rates cardamom as generally safe (++), with no significant contraindications at therapeutic doses (Duke, 2002).
Generally safe at therapeutic doses for short-term use. Hop preparations may enhance the sedative effects of alcohol, benzodiazepines, and other CNS depressants — avoid combination. Not recommended during pregnancy or breastfeeding. May have mild oestrogenic effects due to 8-prenylnaringenin — caution in hormone-sensitive conditions. Fresh hops can cause contact dermatitis in pickers.
Duke (2002) rates hops as +++ and provides clinical evidence (score 2) for sedative activity, consistent with Commission E approval for nervousness, unrest, and sleep disturbances. The primary sedative compound is 2-methyl-3-buten-2-ol, formed from humulone during storage. Duke notes that hop cones have estrogenic activity, explaining occupational menstrual irregularities reported among hop pickers. Dose: 0.5 g dried flower in tea before bed; often combined with valerian. Hops should not be used in depression, as its CNS-depressant effect may worsen depressive symptoms (Duke, 2002).
External Ids
Botanical Description
Large, rhizomatous perennial herb with tall, reed-like leafy stems (pseudostems) formed by overlapping leaf sheaths, arising from a stout underground rhizome. Small, pale flowers with a violet-veined white lip are borne on separate trailing panicles that grow along the ground from the base of the plant. The fruit is a small, ridged, pale green three-sided capsule (the cardamom pod) containing numerous dark, aromatic seeds.[1]
Vigorous, twining perennial climbing vine with rough, hairy stems and deeply lobed, opposite leaves resembling grape leaves. The plant is dioecious; female plants bear the characteristic papery, cone-like flower clusters ('hops'), covered in yellow, resinous lupulin glands, that are the medicinal and brewing part.[1]
Habitat
Native to the moist evergreen forests of the Western Ghats of southern India and Sri Lanka; cultivated in warm, humid, shaded tropical conditions, notably in India, Guatemala and Sri Lanka.[1]
Grows in hedgerows, woodland edges and damp thickets, climbing over other vegetation; native to Europe, Western Asia and North America, and widely cultivated for brewing.
Harvesting
The unripe green pods are hand-picked just before full maturity, then carefully dried (traditionally in the shade or by gentle heat) to preserve the green colour and aromatic oil; the pods are typically used whole or the seeds removed and ground just before use.
The female flower cones are picked in late summer once mature (when the lupulin glands are fully developed and sticky), then dried quickly to preserve the volatile oils and bitter resins.[1]
Traditional Uses
Cardamom has a long Ayurvedic, Middle Eastern and Asian tradition as a warming digestive carminative for indigestion and bloating, a remedy for respiratory complaints such as asthma and bronchitis, and a valued spice for tea, coffee and cooking.[1]
Hop cones have a long European tradition as a calming, sedative herb for nervous tension, restlessness and insomnia, and as a bitter digestive tonic; the sedative reputation, historically noted among hop-pickers who became drowsy from handling the cones, is now linked to GABA-A receptor-active bitter resins.[1]
Preparations
Crushed pods or seeds infused in hot water, or added to tea/coffee, as a traditional carminative digestive preparation.
Dried flower cones infused in hot water as a herbal tea, 500-1000 mg in 150-200 ml, taken 30-60 minutes before bedtime per the EU herbal monograph. Educational reference only, not a prescription.
Tincture (1:5) of the dried cones, 1-2 ml up to three times daily per the EU herbal monograph. Educational reference only, not a prescription.
Concentrated extract standardised to xanthohumol/humulone content, studied for sleep-enhancing activity via GABA-A receptor modulation.
Dosage
The WHO monograph on Semen Cardamomi gives an average DAILY dosage of 1.5 g of the drug, or equivalent preparations; for tincture, a daily dosage equivalent to 12 g. Note the 1.5 g is a daily total, not a per-dose amount. Educational reference only, not a prescription.
The EU herbal monograph distinguishes two uses, in adolescents, adults and elderly. To aid sleep - 500-1000 mg of the comminuted flower in 150-200 mL of boiling water as an infusion, 30-60 minutes before bedtime. In mental stress - 500 mg in 150-200 mL as an infusion, up to 4 times daily. A 1:5 tincture at 1-2 mL up to 3 times daily is also listed. Educational reference only, not a prescription.
References
Lookalikes Review
Drug Class Interactions
Not documented
Pairings
Dangerous Lookalikes
Not documented
References & Sources
- Ashokkumar, K., Murugan, M., Dhanya, M.K. and Warkentin, T.D (2019) 'Botany, traditional uses, phytochemistry and biological activities of cardamom [Elettaria cardamomum (L.) Maton] - A critical review', Journal of Ethnopharmacology, 246, pp. 112244. doi:10.1016/j.jep.2019.112244 Meta-analysis / review
https://doi.org/10.1016/j.jep.2019.112244 - Jamal, A., Javed, K., Aslam, M. and Jafri, M.A (2006) 'Gastroprotective effect of cardamom, Elettaria cardamomum Maton. fruits in rats', Journal of Ethnopharmacology, 103(2), pp. 149-153. doi:10.1016/j.jep.2005.07.016 Preclinical
https://doi.org/10.1016/j.jep.2005.07.016 - Yahyazadeh, R., Ghasemzadeh Rahbardar, M., Razavi, B.M., Karimi, G. and Hosseinzadeh, H (2021) 'The effect of Elettaria cardamomum (cardamom) on the metabolic syndrome: Narrative review', Iranian Journal of Basic Medical Sciences, 24(11), pp. 1462-1469. doi:10.22038/IJBMS.2021.54417.12228 Meta-analysis / review
https://doi.org/10.22038/IJBMS.2021.54417.12228 - Cardenas Garza, G.R., Elizondo Luevano, J.H., Bazaldua Rodriguez, A.F., Chavez Montes, A., Perez Hernandez, R.A. and Martinez Delgado, A.J (2021) 'Benefits of Cardamom (Elettaria cardamomum (L.) Maton) and Turmeric (Curcuma longa L.) Extracts for Their Applications as Natural Anti-Inflammatory Adjuvants', Plants, 10(9), pp. 1908. doi:10.3390/plants10091908 Preclinical
https://doi.org/10.3390/plants10091908 - Sreedharan, S., Nair, V. and Cisneros-Zevallos, L (2023) 'Protective Role of Phenolic Compounds from Whole Cardamom (Elettaria cardamomum (L.) Maton) against LPS-Induced Inflammation in Colon and Macrophage Cells', Nutrients, 15(13), pp. 2965. doi:10.3390/nu15132965 Preclinical
https://doi.org/10.3390/nu15132965 - Almeer, R.S., Alnasser, M., Aljarba, N. and AlBasher, G.I (2021) 'Effects of Green cardamom (Elettaria cardamomum Maton) and its combination with cyclophosphamide on Ehrlich solid tumors', BMC Complementary Medicine and Therapies, 21(1), pp. 133. doi:10.1186/s12906-021-03305-2 Preclinical
https://doi.org/10.1186/s12906-021-03305-2 - Almohammed, H.I., Alkhaibari, A.M. and Alanazi, A.D (2022) 'Antiparasitic effects of Elettaria cardamomum L. essential oil and its main compounds, 1,8-Cineole alone and in combination with albendazole against Echinococcus granulosus protoscoleces', Saudi Journal of Biological Sciences, 29(4), pp. 2811-2818. doi:10.1016/j.sjbs.2022.01.005 Preclinical
https://doi.org/10.1016/j.sjbs.2022.01.005 - Pavarino, M., Marengo, A., Cagliero, C., Bicchi, C., Rubiolo, P. and Sgorbini, B (2023) 'Elettaria cardamomum (L.) Maton Essential Oil: An Interesting Source of Bioactive Specialized Metabolites as Inhibitors of Acetylcholinesterase and Butyrylcholinesterase', Plants, 12(19), pp. 3463. doi:10.3390/plants12193463 Preclinical
https://doi.org/10.3390/plants12193463 - Masoumi-Ardakani, Y., Mahmoudvand, H., Mirzaei, A., Esmaeilpour, K., Ghazvini, H. and Khalifeh, S (2017) 'The effect of Elettaria cardamomum extract on anxiety-like behavior in a rat model of post-traumatic stress disorder', Biomedicine & Pharmacotherapy, 87, pp. 489-495. doi:10.1016/j.biopha.2016.12.116 Preclinical
https://doi.org/10.1016/j.biopha.2016.12.116 - Delgadillo-Puga, C., Torre-Villalvazo, I., Carino-Cervantes, Y.Y., Garcia-Luna, C., Soberanes-Chavez, P. and de Gortari, P (2023) 'Cardamom (Elettaria cardamomum (L.) Maton) Seeds Intake Increases Energy Expenditure and Reduces Fat Mass in Mice by Modulating Neural Circuits That Regulate Adipose Tissue Lipolysis and Mitochondrial Oxidative Metabolism in Liver and Skeletal Muscle', International Journal of Molecular Sciences, 24(4), pp. 3909. doi:10.3390/ijms24043909 Preclinical
https://doi.org/10.3390/ijms24043909 - World Health Organization (2009) 'Semen Cardamomi'. Available at: https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 Traditional / reference
https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 - Bhilave, M.P., Bhosale, S.V. and Nadaf, S.B (2013) 'Evaluation of antibacterial activity of cardamom seeds of Elettaria cardamomum', 4(1), pp. 66--69. Traditional / reference
https://scholar.google.com/scholar?q=Evaluation%20of%20antibacterial%20activity%20of%20cardamom%20seeds%20of%20Elettaria%20cardamomum - Jamal, A., Javed, K., Aslam, M. and Jafri, M.A (2006) 'Gastroprotective effect of cardamom, Elettaria cardamomum (Maton) Fruits in Rats', 103(2), pp. 149--153. doi:10.1016/j.jep.2005.09.040 Traditional / reference
https://doi.org/10.1016/j.jep.2005.09.040 - Korikanthimath, V.S. and Hiremath, G.M (2002) 'Cardamom (Elettaria cardamomum Maton)', pp. 144--157. Traditional / reference
https://scholar.google.com/scholar?q=Cardamom%20%28Elettaria%20cardamomum%20Maton%29 - Royal Botanic Gardens, Kew (n.d.) 'Elettaria cardamomum (L.) Maton'. Available at: https://powo.science.kew.org/taxon/urn:lsid:http://ipni.org:names:796793-1 Traditional / reference
https://powo.science.kew.org/taxon/urn:lsid:http://ipni.org:names:796793-1 - Verma, S.K., Jain, V. and Katewa, S.S (2009) 'Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum)', 46(6), pp. 503--506. Traditional / reference
https://scholar.google.com/scholar?q=Blood%20pressure%20lowering%2C%20fibrinolysis%20enhancing%20and%20antioxidant%20activities%20of%20cardamom%20%28Elettaria%20cardamomum%29 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
- Lee, H., Chung, S.H., Kwon, D.J., Nam, M.J. et al (2024) 'Sleep-enhancing effect of Hongcheon-hop (Humulus lupulus L.) extract containing xanthohumol and humulone through GABA-A receptor', Journal of Ethnopharmacology, 338(Pt 2), pp. 119019. doi:10.1016/j.jep.2024.119019 Preclinical
https://doi.org/10.1016/j.jep.2024.119019 - Kenda, M., Glavač, N.K., Nagy, M. and Sollner Dolenc, M (2021) 'Herbal Products Used in Menopause and for Gynecological Disorders', Molecules, 26(24), pp. 7421. doi:10.3390/molecules26247421 Traditional / reference
https://doi.org/10.3390/molecules26247421 - Dietz, B.M., Hajirahimkhan, A., Dunlap, T.L. and Bolton, J.L (2016) 'Botanicals and Their Bioactive Phytochemicals for Women's Health', Pharmacological Reviews, 68(4), pp. 1026-1073. doi:10.1124/pr.115.010843 Traditional / reference
https://doi.org/10.1124/pr.115.010843 - Sun, X.L., Xia, T.S., Jiang, Y.P., Wang, N.N., Xu, L.C. and Han, T (2022) 'Humulus lupulus L. extract and its active constituent xanthohumol attenuate oxidative stress and nerve injury induced by iron overload via activating AKT/GSK3beta and Nrf2/NQO1 pathways', Journal of Natural Medicines, 76(4), pp. 801-814. doi:10.1007/s11418-022-01642-1 Preclinical
https://doi.org/10.1007/s11418-022-01642-1 - Karbalaei, N., Sadeghi, N., Nekoeian, A. and Malekzadeh, A (2019) 'Impact of Hydroalcoholic Extract of Humulus Lupulus L. on Sperm Quality, Reproductive Organs and Hormones in Male Rats', Chinese Journal of Integrative Medicine, 25(9), pp. 1-8. doi:10.1007/s11655-019-3025-7 Preclinical
https://doi.org/10.1007/s11655-019-3025-7 - Xia, T.S., Lin, L.Y., Zhang, Q.Y., Jiang, Y.P., Li, C.H. and Liu, X.Y (2019) 'Humulus lupulus L. Extract Prevents Ovariectomy-Induced Osteoporosis in Mice and Regulates Activities of Osteoblasts and Osteoclasts', Chinese Journal of Integrative Medicine, 27(1), pp. 31-38. doi:10.1007/s11655-019-2700-z Preclinical
https://doi.org/10.1007/s11655-019-2700-z - Hurth, Z., Faber, M.L., Gendrisch, F., Holzer, M., Haarhaus, B. and Cawelius, A (2022) 'The Anti-Inflammatory Effect of Humulus lupulus Extract In Vivo Depends on the Galenic System of the Topical Formulation', Pharmaceuticals, 15(3), pp. 350. doi:10.3390/ph15030350 Preclinical
https://doi.org/10.3390/ph15030350 - Caban, M., Chojnacka, K., Owczarek, K., Laskowska, J., Fichna, J. and Podsedek, A (2020) 'Spent hops (Humulus Lupulus L.) extract as modulator of the inflammatory response in lipopolysaccharide stimulated RAW 264.7 macrophages', Journal of Physiology and Pharmacology, 71(1). doi:10.26402/jpp.2020.1.05 Preclinical
https://doi.org/10.26402/jpp.2020.1.05 - Wang, S., Dunlap, T.L., Howell, C.E., Mbachu, O.C., Rue, E.A. and Phansalkar, R (2016) 'Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation', Chemical Research in Toxicology, 29(7), pp. 1142-1150. doi:10.1021/acs.chemrestox.6b00112 Preclinical
https://doi.org/10.1021/acs.chemrestox.6b00112 - Kyrou, I., Christou, A., Panagiotakos, D., Stefanaki, C., Skenderi, K. and Katsana, K (2017) 'Effects of a hops (Humulus lupulus L.) dry extract supplement on self-reported depression, anxiety and stress levels in apparently healthy young adults: a randomized, placebo-controlled, double-blind, crossover pilot study', Hormones, 16(2), pp. 171-180. doi:10.14310/horm.2002.1738 Randomized trial
https://doi.org/10.14310/horm.2002.1738 - Hege, M., Jung, F., Sellmann, C., Jin, C., Ziegenhardt, D. and Hellerbrand, C (2017) 'An iso-alpha-acid-rich extract from hops (Humulus lupulus) attenuates acute alcohol-induced liver steatosis in mice', Nutrition, 41, pp. 70-77. doi:10.1016/j.nut.2017.07.010 Preclinical
https://doi.org/10.1016/j.nut.2017.07.010 - European Medicines Agency (HMPC) (2014) 'Community herbal monograph on Humulus lupulus L., flos, Revision 1'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-humulus-lupulus-l-flos-revision-1_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-humulus-lupulus-l-flos-revision-1_en.pdf - Becker, A., Felgentreff, F., Schröder, H., Meier, B. and Brattstrom, A (2014) 'The anxiolytic effects of a Valerian extract is based on valerenic acid', pp. 267. Traditional / reference
https://scholar.google.com/scholar?q=The%20anxiolytic%20effects%20of%20a%20Valerian%20extract%20is%20based%20on%20valerenic%20acid - Koetter, U. and Blumenthal, M (2010) 'Valerian and hops for insomnia: overview of clinical data', pp. 44--50. Traditional / reference
https://scholar.google.com/scholar?q=Valerian%20and%20hops%20for%20insomnia%3A%20overview%20of%20clinical%20data - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003 - Koetter, U., Schrader, E., Kaeufeler, R. and Brattstroem, A (2007) 'A randomized, double blind, placebo-controlled, prospective clinical study to demonstrate clinical efficacy of a fixed valerian hops extract combination (Ze 91019) in patients suffering from non-organic sleep disorder', Phytotherapy Research, 21(9), pp. 847-851. doi:10.1002/ptr.2167 Randomized trial
https://doi.org/10.1002/ptr.2167 - Ngan, A. and Conduit, R (2011) 'A double-blind, placebo-controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality', Phytotherapy Research, 25(8), pp. 1153-1159. doi:10.1002/ptr.3400 Randomized trial
https://doi.org/10.1002/ptr.3400 - Totally Wild UK 'Hops (Humulus lupulus) Identification Guide'. Available at: https://totallywilduk.co.uk/2022/12/08/hops-humulus-lupulus-identification-guide/ Traditional / reference
https://totallywilduk.co.uk/2022/12/08/hops-humulus-lupulus-identification-guide/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.