Plant Comparison

Cumin vs Wood Betony

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ACuminCuminum cyminumApiaceaeFull monograph →
Plant BWood BetonyStachys officinalisLamiaceaeFull monograph →

At a glance

Cumin and Wood Betony: they share 7 indicated uses (arthritis / joint pain, bloating, indigestion, …); 4 pharmacological actions in common.

CuminWood Betony
Constituents13
Pharmacological actions55
Indicated uses1011
Safety notes32
Cited sources2713
Indicated uses
Only Cumin
Infection (general)Metabolic supportWounds
Shared (7)
Arthritis / joint painBloatingIndigestionInflammation (general)Menstrual crampsMuscle spasmSkin irritation
Only Wood Betony
AnxietyHeadacheNervous tensionStress
Pharmacological actions
Only Cumin
Antimicrobial
Shared (4)
Anti-inflammatoryAntioxidantAntispasmodicDigestive aid
Only Wood Betony
Anxiolytic / calming

Evidence face-off — shared uses

ConditionCuminWood BetonyVerdict
Arthritis / joint pain9/101/10Stronger for Cumin
Bloating10/101/10Stronger for Cumin
Indigestion10/101/10Stronger for Cumin
Inflammation (general)9/102/10Stronger for Cumin
Menstrual cramps10/101/10Stronger for Cumin
Muscle spasm10/101/10Stronger for Cumin
Skin irritation9/101/10Stronger for Cumin

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Cuminaldehyde[1]

Cuminaldehyde (4-isopropylbenzaldehyde) is the dominant constituent of cumin-seed essential oil (around two-thirds of the oil) and the main driver of its antimicrobial, antifungal (anti-aflatoxigenic) and antioxidant activity.

Essential (volatile) oil
Phenylethanoid and iridoid glycosides (acteoside, harpagide, harpagoside, aucubin, betonyosides)[9, 10, 11]

Anti-inflammatory and antispasmodic constituents.

Iridoid glycosidesHarpagosideGlycosidesVerbascoside (acteoside)
Alkaloids (stachydrine, betaine)[11]

Characteristic nitrogen-containing constituents.

Alkaloids
Phenolic acids (rosmarinic, caffeic, chlorogenic), tannins and volatile oil[2, 3, 4, 7, 11, 12]

Antioxidant, astringent and aromatic constituents; methanolic extract of the herb showed strong free-radical-scavenging and lipid-peroxidation-inhibiting activity in vitro.

Phenolic acidsEssential (volatile) oilChlorogenic acidRosmarinic acidCaffeic acidTannins

Pharmacological Actions

Anti-inflammatory[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]
Antimicrobial[1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]
Antioxidant[1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]
Antispasmodic[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22]

Antispasmodic (cramp easing)

Digestive aid[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22]
Anti-inflammatory[9, 11]

Anti-inflammatory and antispasmodic

Antioxidant[1, 2, 5, 8, 12]

Antioxidant - among the strongest free-radical scavengers in a comparative study of Lamiaceae herbs

Antispasmodic[11]

Anti-inflammatory and antispasmodic

Anxiolytic / calming[11, 13]

Gentle calmative for anxiety; Nervine / relaxant for nervous tension and tension headaches (especially headache worsened by anxiety or muscle tension)

Digestive aid[11]

Digestive bitter for indigestion, mild stomach upset and bloating

Traditional & Indicated Uses

Arthritis / joint pain[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]Strong · 9/10

inferred from anti-inflammatory action

Evidence: 9
Label: Arthritis / joint pain
Bloating[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22]Strong · 10/10

inferred from digestive action

Evidence: 10
Label: Bloating
Indigestion[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22]Strong · 10/10

inferred from digestive action

Evidence: 10
Label: Indigestion
Infection (general)[1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]Strong · 9/10

inferred from antimicrobial action

Evidence: 9
Label: Infection (general)
Inflammation (general)[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]Strong · 9/10

inferred from anti-inflammatory action

Evidence: 9
Label: Inflammation (general)
Menstrual cramps[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22]Strong · 10/10

inferred from antispasmodic action

Evidence: 10
Label: Menstrual cramps
Metabolic support[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 23, 24, 25, 26]Strong · 10/10
Evidence: 10
Label: Metabolic support
Muscle spasm[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22]Strong · 10/10

inferred from antispasmodic action

Evidence: 10
Label: Muscle spasm
Skin irritation[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]Strong · 9/10

inferred from anti-inflammatory action

Evidence: 9
Label: Skin irritation
Wounds[1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]Strong · 9/10

inferred from antimicrobial action

Evidence: 9
Label: Wounds
Anxiety[11, 13]Traditional · 1/10

Gentle calmative for anxiety; Nervine / relaxant for nervous tension and tension headaches (especially headache worsened by anxiety or muscle tension)

Evidence: 1
Label: Anxiety
Arthritis / joint pain[11]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bloating[11]Traditional · 1/10

Digestive bitter for indigestion, mild stomach upset and bloating

Evidence: 1
Label: Bloating
Headache[11, 13]Traditional · 1/10

Nervine / relaxant for nervous tension and tension headaches (especially headache worsened by anxiety or muscle tension)

Evidence: 1
Label: Headache
Indigestion[11]Traditional · 1/10

Digestive bitter for indigestion, mild stomach upset and bloating

Evidence: 1
Label: Indigestion
Inflammation (general)[9, 11]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Inflammation (general)
Menstrual cramps[11]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Menstrual cramps
Muscle spasm[11]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Muscle spasm
Nervous tension[11, 13]Traditional · 1/10

Nervine / relaxant for nervous tension and tension headaches (especially headache worsened by anxiety or muscle tension)

Evidence: 1
Label: Nervous tension
Skin irritation[11]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Stress[11, 13]Traditional · 1/10

inferred from anxiolytic action

Evidence: 1
Label: Stress

Safety, Cautions & Contraindications

Safety note[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]Info

Food amounts are generally considered safe; in the US it’s listed as GRAS as a spice/flavoring (LactMed, 2025).

Safety note[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21]Info

Allergy risk: cumin can trigger allergic reactions in sensitive people; cross-reactivity is reported within Apiaceae spices (e.g., celery/coriander/fennel/cumin) and in “pollen–spice” allergy patterns (Lisiecka et al., 2025; Berghea et al., 2025).

Safety note[2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 27]Caution

Duke (2002) rates cumin as +++ and notes carminative, digestive, and aperitif activities at experimental levels (score 1). The plant demonstrates estrogenic activity in animal studies and has antifungal and antioxidant properties. Photodermatitic potential (phototoxicity) of the essential oil is noted — users should avoid sun exposure after topical application. Duke advises caution in pregnancy due to potential emmenagogue and antifertility effects at high medicinal doses (Duke, 2002).

Safety note[11]Info

Generally well tolerated, with occasional mild nausea the main reported effect.

Safety note[11, 13]Caution

Traditionally avoided in pregnancy (uterine reputation), and it may lower blood pressure - use caution with blood-pressure medicines.

External Ids

Gbif: 3034775
Powo: urn:lsid:ipni.org:names:840882-1
Wikidata: Q132624
Gbif: 7777194
Wikidata: Q157297

Botanical Description

Slender annual herb with finely divided, thread-like leaves similar to dill or fennel but smaller. Small white or pale pink flowers are borne in small compound umbels, followed by small, ridged, boat-shaped, strongly aromatic seeds.

Height: 20-30 cm
Habit: Slender, low-growing annual herb
Leaves: Finely divided, thread-like, similar to dill but smaller
Flowers: Small white or pale pink flowers in small compound umbels
Stem: Slender, branching
Root: Slender taproot
Fruit: Small, ridged, boat-shaped, strongly aromatic seed (mericarp)
Flowering Period: Summer

Perennial herb (Lamiaceae), 30-60 cm tall, with square, mostly unbranched, hairy stems. Leaves are mostly basal, oblong to heart-shaped, toothed and wrinkled. Small, reddish-purple, two-lipped flowers are borne in a dense, interrupted terminal spike.[11]

Height: 30-60 cm
Habit: Erect perennial herb
Leaves: Mostly basal, oblong to heart-shaped, toothed, wrinkled
Flowers: Small, reddish-purple, two-lipped, in a dense interrupted terminal spike
Stem: Square, mostly unbranched, hairy
Root: Fibrous perennial rootstock
Fruit: Four small nutlets (typical Lamiaceae schizocarp)
Flowering Period: June-September

Habitat

Believed native to the eastern Mediterranean and Central Asia; cultivated widely in warm, dry climates including India, the Middle East and North Africa as a major spice crop.

Native to Europe, growing in open woodland, grassland, hedgebanks and heathland on well-drained, often slightly acidic soils.[11]

Harvesting

The seed heads are cut when the fruit has ripened but before it shatters, usually in mid- to late summer, then dried and threshed.

Parts: Seed
Season: Mid- to late summer

Aerial flowering parts are cut during flowering (summer) and dried.[11]

Parts: Aerial parts (flowering herb)
Season: Summer, during flowering

Traditional Uses

Cumin seed has an ancient culinary and medicinal history across the Middle East, South Asia and the Mediterranean as a warming digestive carminative for indigestion, bloating and cramping, and is one of the most widely used spices worldwide.

Wood betony has an ancient European reputation - praised in Anglo-Saxon and medieval herbals as a cure-all, giving rise to the saying 'sell your coat and buy betony' - as a gentle nervine for headache, anxiety and nervous tension, and as a digestive bitter. Modern phytochemical studies confirm it is among the strongest antioxidants of the Lamiaceae family, alongside anti-inflammatory and antispasmodic constituents.[11, 13]

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Preparations

Not documented

Infusion (tea)[11]

Dried aerial parts steeped in hot water - the classic calming and digestive preparation.

Dosage

Not documented

Infusion (tea)[11, 13]

Traditional guidance suggests roughly 1-2 g dried herb per cup as an infusion, up to three times daily. Educational reference only, not a prescription; use caution alongside blood-pressure medicines and avoid in pregnancy.

References

Not documented

REF-1055, REF-1056, REF-1057, REF-1058, REF-1059, REF-1042, REF-1060, REF-1061, REF-1062, REF-1063

References & Sources

  1. Ben Miri, Y. and Djenane, D (2018) 'Evaluation of Protective Impact of Algerian Cuminum cyminum L. and Coriandrum sativum L. Essential Oils on Aspergillus flavus Growth and Aflatoxin B1 Production', Pakistan Journal of Biological Sciences, 21(2), pp. 67--77. doi:10.3923/pjbs.2018.67.77 Preclinical
    https://doi.org/10.3923/pjbs.2018.67.77
  2. Allaq, A.A. and Sidik, N.J (2020) 'Cumin (Cuminum cyminum L.): A review of its ethnopharmacology, phytochemistry and biological activities'. Available at: https://bmrat.org/index.php/BMRAT/article/view/634 Traditional / reference
    https://bmrat.org/index.php/BMRAT/article/view/634
  3. Berghea, E.C. et al (2025) 'Spices, herbs and allergic reactions in children: myth or reality?'. doi:10.3389/falgy.2025.1698559/full Clinical study
    https://doi.org/10.3389/falgy.2025.1698559/full
  4. Britannica (2025) 'Cumin'. Available at: https://www.britannica.com/plant/cumin Traditional / reference
    https://www.britannica.com/plant/cumin
  5. EUR-Lex (2015) 'Official Journal of the European Union C 76/2015 (Latvian text; includes “Romiešu ķimenes (cumin)'. Available at: https://eur-lex.europa.eu/legal-content/LV/TXT/HTML/?uri=OJ%3AC%3A2015%3A076%3AFULL Traditional / reference
    https://eur-lex.europa.eu/legal-content/LV/TXT/HTML/?uri=OJ%3AC%3A2015%3A076%3AFULL
  6. EUR-Lex (2020) 'Official Journal of the European Union C 108/2020 (Latvian text; includes “kumins (romiešu ķimenes)'. Available at: https://eur-lex.europa.eu/legal-content/LV/TXT/HTML/?uri=CELEX%3A52020XC0401%2804%29 Traditional / reference
    https://eur-lex.europa.eu/legal-content/LV/TXT/HTML/?uri=CELEX%3A52020XC0401%2804%29
  7. http://letonika.lv/ (2021) 'Latviešu—angļu vārdnīca: ķimenes (includes “Romiešu ķimenes = cumin'. Available at: http://letonika.lv/ Traditional / reference
    http://letonika.lv/
  8. Karimian, J. et al (2021) 'The effects of cumin (Cuminum cyminum L.) supplementation on glycemic indices: a systematic review and meta-analysis'. doi:10.1002/ptr.7075 Meta-analysis / review
    https://doi.org/10.1002/ptr.7075
  9. KPBS (2015) 'Cumin: The Ancient Spice That'. Available at: https://www.kpbs.org/news/2015/03/11/cumin-the-ancient-spice-thats-traveled-the-globe Traditional / reference
    https://www.kpbs.org/news/2015/03/11/cumin-the-ancient-spice-thats-traveled-the-globe
  10. LactMed (2025) 'Cumin'. Available at: https://www.ncbi.nlm.nih.gov/books/NBK501873/ Traditional / reference
    https://www.ncbi.nlm.nih.gov/books/NBK501873/
  11. Lisiecka, M.F. et al (2025) 'Allergic reactions to spices: a review of sensitivities to pepper, cumin, oregano, anise, mustard and other spices'. Available at: https://pubmed.ncbi.nlm.nih.gov/40341008/ Traditional / reference
    https://pubmed.ncbi.nlm.nih.gov/40341008/
  12. Liu, M. et al (2025) 'Potential benefits of Cuminum cyminum L'. doi:10.3389/fnut.2025.1618108/full Meta-analysis / review
    https://doi.org/10.3389/fnut.2025.1618108/full
  13. Morshedi, D. et al (2015) 'Cuminaldehyde as the Major Component of Cuminum cyminum…', 80(10), pp. H2336--H2345. doi:10.1111/1750-3841.13016 Preclinical
    https://doi.org/10.1111/1750-3841.13016
  14. Nabhan, G.P (2014) 'Cumin, Camels, and Caravans: A Spice Odyssey'. Available at: https://www.ucpress.edu/book/9780520379244/cumin-camels-and-caravans Traditional / reference
    https://www.ucpress.edu/book/9780520379244/cumin-camels-and-caravans
  15. Nouri, A. et al (2024) 'Phytochemical composition… (includes GC–MS profile of cumin seed essential oil)'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC11606850/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC11606850/
  16. PubChem (n.d.). Available at: https://pubchem.ncbi.nlm.nih.gov/compound/Cumin-Oil Traditional / reference
    https://pubchem.ncbi.nlm.nih.gov/compound/Cumin-Oil
  17. Royal Botanic Gardens, Kew (n.d.) 'Cuminum cyminum L'. Available at: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:840882-1 Traditional / reference
    https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:840882-1
  18. SekoEko (n.d.) 'Kumīns, ķimenes un citi līdzinieki!'. Available at: https://sekoeko.lv/lv/kumins-kimenes-un-citi-lidzinieki Traditional / reference
    https://sekoeko.lv/lv/kumins-kimenes-un-citi-lidzinieki
  19. Tavakoli-Rouzbehani, O.M. et al (2022) 'The effects of cumin supplementation on lipid parameters: a systematic review and meta-analysis of RCTs'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC9881733/ Meta-analysis / review
    https://pmc.ncbi.nlm.nih.gov/articles/PMC9881733/
  20. Vikipēdija (n.d.). Available at: https://lv.wikipedia.org/wiki/Kum%C4%ABns Traditional / reference
    https://lv.wikipedia.org/wiki/Kum%C4%ABns
  21. Wikisource (2018) '1911 Encyclopædia Britannica: Cumin'. Available at: https://en.wikisource.org/wiki/1911_Encyclop%C3%A6dia_Britannica/Cumin Traditional / reference
    https://en.wikisource.org/wiki/1911_Encyclop%C3%A6dia_Britannica/Cumin
  22. Amin, E.A., Ismail, E., Mahboobeh, R. and Tabandeh, S (2024) 'The effect of Cuminum cyminum on the return of bowel motility after abdominal surgery: a triple-blind randomized clinical trial', BMC Complementary Medicine and Therapies, 24(1). doi:10.1186/s12906-024-04530-1 Randomized trial
    https://doi.org/10.1186/s12906-024-04530-1
  23. Hadi, A., Mohammadi, H., Hadi, Z., Roshanravan, N. and Kafeshani, M (2018) 'Cumin (Cuminum cyminum L.) is a safe approach for management of lipid parameters: A systematic review and meta-analysis of randomized controlled trials', Phytotherapy Research, 32(11), pp. 2146--2154. doi:10.1002/ptr.6162 Meta-analysis / review
    https://doi.org/10.1002/ptr.6162
  24. Tavakoli-Rouzbehani, O.M., Faghfouri, A.H., Anbari, M., Papi, S., Shojaei, F.S., Ghaffari, M. and Alizadeh, M (2021) 'The effects of Cuminum cyminum on glycemic parameters: A systematic review and meta-analysis of controlled clinical trials', Journal of Ethnopharmacology, pp. 2021. doi:10.1016/j.jep.2021.114510 Meta-analysis / review
    https://doi.org/10.1016/j.jep.2021.114510
  25. Karimian, J., Farrokhzad, A. and Jalili, C (2021) 'The effect of cumin (Cuminum cyminum L.) supplementation on glycemic indices: A systematic review and meta-analysis of randomized controlled trials', Phytotherapy Research, 35(8), pp. 4127--4135. doi:10.1002/ptr.7075 Meta-analysis / review
    https://doi.org/10.1002/ptr.7075
  26. Morovati, A., Pourghassem Gargari, B. and Sarbakhsh, P (2019) 'Effects of cumin (Cuminum cyminum L.) essential oil supplementation on metabolic syndrome components: A randomized, triple-blind, placebo-controlled clinical trial', Phytotherapy Research, 33(12), pp. 3261--3269. doi:10.1002/ptr.6500 Randomized trial
    https://doi.org/10.1002/ptr.6500
  27. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  1. Slapsyte, G., Dedonyte, V., Adomeniene, A., Lazutka, J.R. and others (2019) 'Genotoxic properties of Betonica officinalis, Gratiola officinalis, Vincetoxicum luteum and Vincetoxicum hirundinaria extracts', Food and Chemical Toxicology, 134, pp. 110815. doi:10.1016/j.fct.2019.110815 Preclinical
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  8. Stegarus, D.I., Lengyel, E., Apostolescu, G.F., Botoran, O.R. and others (2021) 'Phytochemical Analysis and Biological Activity of Three Stachys Species (Lamiaceae) from Romania', Plants, 10(12), pp. 2710. doi:10.3390/plants10122710 Preclinical
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  9. Háznagy-Radnai, E., Balogh, Á., Czigle, S., Máthé, I. and others (2012) 'Antiinflammatory activities of Hungarian Stachys species and their iridoids', Phytotherapy Research, 26(4), pp. 505-509. doi:10.1002/ptr.3582 Preclinical
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.