Plant Comparison

Blessed Thistle vs Tansy

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
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Plant ABlessed ThistleCnicus benedictusAsteraceaeFull monograph →
Plant BTansyTanacetum vulgareAsteraceaeFull monograph →

At a glance

Blessed Thistle and Tansy: both belong to the Asteraceae family; they share 7 indicated uses (arthritis / joint pain, bloating, indigestion, …); 3 pharmacological actions in common.

Blessed ThistleTansy
Constituents33
Pharmacological actions75
Indicated uses109
Safety notes32
Cited sources1216
Indicated uses
Only Blessed Thistle
Loss of appetiteCancer (anticancer research)Lactation support
Shared (7)
Arthritis / joint painBloatingIndigestionInfection (general)Inflammation (general)Skin irritationWounds
Only Tansy
Menstrual crampsMuscle spasm
Pharmacological actions
Only Blessed Thistle
Anticancer (preclinical)Appetite stimulantBitter digestive tonic / stomachicGalactagogue (supports lactation)
Shared (3)
Anti-inflammatoryAntimicrobialDigestive aid
Only Tansy
AntioxidantAntispasmodic

Evidence face-off — shared uses

ConditionBlessed ThistleTansyVerdict
Arthritis / joint pain1/101/10Comparable evidence
Bloating1/101/10Comparable evidence
Indigestion1/101/10Comparable evidence
Infection (general)1/102/10Comparable evidence
Inflammation (general)1/101/10Comparable evidence
Skin irritation1/101/10Comparable evidence
Wounds1/101/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Sesquiterpene lactones (cnicin, arctigenin, arctiin)[4]

Cnicin is the principal bitter principle and main bioactive compound.

Sesquiterpene lactonesSesquiterpenesArctigenin / arctiin
Flavonoids, lignans and tannins[4]

Additional antioxidant and astringent constituents.

FlavonoidsLignansTannins
Volatile oil[4]

Aromatic constituents of the herb.

Essential (volatile) oil
Essential oil (thujone, camphor)[1]

Thujone is the neurotoxic, safety-limiting constituent responsible for tansy's real internal-use toxicity.

Essential (volatile) oilCamphorTerpenes / terpenoids
Sesquiterpene lactones[2]

Contribute to the plant's bitter taste and antimicrobial activity.

Sesquiterpene lactonesSesquiterpenes
Flavonoids[7]

Contribute to antioxidant activity.

Flavonoids

Pharmacological Actions

Anti-inflammatory[1, 4, 7]

Antimicrobial and anti-inflammatory (attributed to cnicin)

Anticancer (preclinical)[5]
Antimicrobial[1, 4, 6]

Antimicrobial and anti-inflammatory (attributed to cnicin)

Appetite stimulant[4, 11]

Appetite stimulant for loss of appetite (approved use under German Commission E)

Bitter digestive tonic / stomachic[4, 11]

Bitter digestive / stomachic for indigestion and dyspepsia (stimulates saliva and gastric secretion)

Digestive aid[4, 11]

Bitter digestive / stomachic for indigestion and dyspepsia (stimulates saliva and gastric secretion)

Galactagogue (supports lactation)[11, 12]

Galactagogue to support breast-milk supply (traditional; no valid clinical-trial evidence)

Anti-inflammatory[2, 11, 12, 13]
Antimicrobial[1, 4, 5, 6, 8, 11, 12, 13]
Antioxidant[2, 4, 7, 11, 12, 13]
Antispasmodic[11, 12, 13]

Antispasmodic (cramp easing)

Digestive aid[11, 12, 13]

Traditional & Indicated Uses

Loss of appetite[4, 11]Traditional · 1/10

Appetite stimulant for loss of appetite (approved use under German Commission E)

Evidence: 1
Label: Loss of appetite
Arthritis / joint pain[4]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bloating[4, 11]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Cancer (anticancer research)[5]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Indigestion[4, 11]Traditional · 1/10

Bitter digestive / stomachic for indigestion and dyspepsia (stimulates saliva and gastric secretion)

Evidence: 1
Label: Indigestion
Infection (general)[4]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[4]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Lactation support[11, 12]Traditional · 1/10

Galactagogue to support breast-milk supply (traditional; no valid clinical-trial evidence)

Evidence: 1
Label: Lactation support
Skin irritation[4]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[4]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Arthritis / joint pain[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bloating[11, 12, 13]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Indigestion[11, 12, 13]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Indigestion
Infection (general)[6, 11, 12, 13]Traditional · 2/10

inferred from antimicrobial action

Evidence: 2
Label: Infection (general)
Inflammation (general)[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Menstrual cramps[11, 12, 13]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Menstrual cramps
Muscle spasm[11, 12, 13]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Muscle spasm
Skin irritation[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[11, 12, 13]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds

Safety, Cautions & Contraindications

Safety note[11]Info

As a member of the daisy family (Asteraceae/ragweed), it can cause allergic reactions in sensitive people; high doses reportedly cause stomach cramps, nausea and vomiting.

Safety note[11]Caution

Avoid during pregnancy because of a traditional uterine-stimulating reputation.

Safety note[12]Info

Although traditionally used to support milk supply, there is no scientifically valid clinical evidence for the galactagogue use.

Safety note[11, 12, 13]Caution

CAUTION: Tansy is considered toxic in medicinal doses and is NOT recommended for internal use. Thujone can cause convulsions, liver and kidney damage. Contraindicated in pregnancy (uterotonic and abortifacient). External use (as insect repellent) is generally safe. For information and historical reference only — do not use internally.

Safety note[11, 12, 13, 14]Caution

Duke (2002) rates tansy as ++ but emphasizes important safety concerns. The plant contains thujone (a neurotoxic ketone) and camphor, making it potentially toxic with internal use. Documented activities include emmenagogue, abortifacient (score 1), and insecticide. Duke strongly cautions against internal use except under professional supervision, noting that historical cases of tansy poisoning have resulted in convulsions and death. Topical use as an insect repellent is safer but should still avoid prolonged skin contact due to the essential oil's sensitizing potential. Strictly contraindicated in pregnancy (Duke, 2002).

External Ids

Gbif: 3127698
Powo: urn:lsid:ipni.org:names:61760-2
Wikidata: Q15548577
Gbif: 3118274
Wikidata: Q27079

Botanical Description

Branching annual herb with a hairy, reddish, ridged stem and spiny, deeply lobed leaves with prominent pale veins. The flower heads are pale yellow, thistle-like, surrounded by a whorl of spiny, leaf-like bracts, giving the plant its 'spotted thistle' appearance.[4]

Height: 20-60 cm
Habit: Branching, hairy annual herb
Leaves: Spiny, deeply lobed, with prominent pale veins
Flowers: Pale yellow, thistle-like flower heads surrounded by spiny bracts
Stem: Hairy, reddish, ridged, branching
Root: Shallow taproot
Fruit: Ribbed achene with a feathery pappus
Flowering Period: June-August

Aromatic perennial herb (Asteraceae), 50-120 cm tall, with erect, reddish, ridged stems. Leaves are finely divided, fern-like and strongly camphor-scented. Flat-topped clusters of small, yellow, button-like flower heads lack ray florets (petals).[11]

Height: 50-120 cm
Habit: Erect, aromatic perennial herb
Leaves: Finely divided, fern-like, strongly camphor-scented
Flowers: Small, yellow, button-like heads with no ray florets, in flat-topped clusters
Stem: Erect, reddish, ridged
Root: Spreading rhizomatous root system
Fruit: Small ribbed achenes (typical Asteraceae)
Flowering Period: July-September

Habitat

Grows on dry, sunny waste ground, roadsides and rocky slopes; native to the Mediterranean region and Western Asia and naturalised elsewhere as a garden escape.[4]

Native to Europe and temperate Asia, widely naturalised elsewhere; grows on roadsides, waste ground, riverbanks and disturbed grassland.[11]

Harvesting

The flowering aerial parts are cut as the plant comes into flower, in summer, and dried in a warm, shaded, airy place to preserve the bitter principle cnicin.[4]

Parts: Aerial parts (flowering herb)
Season: Summer, at flowering

Flowering aerial parts are cut in summer, when in full flower, and dried for external/historical use; given this plant's real toxicity (thujone content) at internal doses, this record does not recommend or describe internal harvesting for medicinal consumption.[11]

Parts: Flower, Leaf, Stem
Season: Summer, at full flower

Traditional Uses

Blessed thistle has a long European folk reputation as a bitter digestive tonic for loss of appetite and dyspepsia (an approved use under German Commission E) and, more anecdotally, as a traditional galactagogue to support breast-milk supply, though robust clinical evidence for the latter is lacking.[4, 11]

Tansy has a long European history as a strewing herb, insect repellent and, historically, an internal vermifuge and emmenagogue, but its thujone and camphor content make internal medicinal use unsafe by modern standards. Today it is used, with caution, mainly as an external insect repellent; the traditional internal uses are recorded here for historical reference only, not as a recommendation.[11]

Preparations

Infusion[11]

Dried flowering herb infused briefly in hot water as a bitter digestive tea, taken before meals.

Dried herb (insect repellent, external)[11]

Dried flowering tops used as a traditional moth/insect deterrent, for example in sachets.

Essential oil (external, historical)[1]

Used historically as an insect repellent; prolonged skin contact should still be avoided given its sensitising potential.

Dosage

Infusion[11]

Traditional herbal references suggest around 1-2 g of dried herb per cup, taken before meals, up to three times daily. Educational reference only, not a prescription.

Internal use[11, 12, 13]

Tansy is NOT recommended for internal use at any dose given its thujone content and documented toxicity (convulsions, liver/kidney damage) - internal use recorded here is for historical reference only. External use (e.g. as an insect repellent) should avoid prolonged skin contact. Educational reference only, not a prescription; strictly avoid in pregnancy.

References

REF-0773, REF-0774, REF-0775, REF-0419, REF-1995, REF-1996, REF-1997, REF-1998, REF-1999, REF-2000
REF-1293, REF-1294, REF-1295, REF-1296, REF-1297, REF-1298, REF-1299, REF-1300, REF-1301, REF-1302

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Dangerous Lookalikes

Not documented

Safety note[15, 16]Dangerous
Dangerous Plant: jacobaea-vulgaris
Confused Part: Yellow-flowered plant gathered for its aromatic foliage and flowers; tansy ragwort shares the name, the yellow colour and rough ground.
Confusion Context: Common tansy (Tanacetum vulgare) is gathered for its aromatic fern-like foliage and flat clusters of yellow button flowers. Tansy ragwort (Jacobaea vulgaris, syn. Senecio jacobaea) shares the 'tansy' name, the yellow colouring and the same rough grassland, and the two are confused. Ragwort contains hepatotoxic pyrrolizidine alkaloids that cause cumulative liver damage and can sicken or kill livestock and people, with the highest risk once cut or dried into hay or herbal material. Because both are yellow-flowered weeds of the same ground, correct identification matters before gathering.
Distinguishing Features: Flowers (decisive): common tansy has flat-topped clusters of yellow BUTTON flowers with no petals (ray florets). Tansy ragwort has open, daisy-like yellow flowers with about 13 spreading petals. Petalled daisy flowers = ragwort, not tansy., Leaves: common tansy has finely divided, fern-like aromatic leaves; ragwort leaves are blunter, 'kale-like', ruffled and lobed., Smell: crushed tansy is strongly aromatic; ragwort lacks that camphor-like tansy scent.
Key Test: Look at the flowers. Flat clusters of petal-less yellow buttons on strongly aromatic fern-like foliage = common tansy. Open daisy-like yellow flowers with about 13 petals and ruffled 'kale-like' leaves = tansy ragwort - toxic to the liver, do not gather it. If the flowers have petals, it is not tansy.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Rezig, K., Benkaci-Ali, F., Foucaunier, M.L., Laurent, S. et al (2023) 'HPLC/ESI-MS Characterization of Phenolic Compounds from Cnicus benedictus L. Roots: A Study of Antioxidant, Antibacterial, Anti-Inflammatory, and Anti-Alzheimer's Activity', Chemistry & Biodiversity, 21(1), pp. e202300724. doi:10.1002/cbdv.202300724 Preclinical
    https://doi.org/10.1002/cbdv.202300724
  2. Ahmadimoghaddam, D., Sadeghian, R., Ranjbar, A., Izadidastenaei, Z. and Mohammadi, S (2020) 'Antinociceptive activity of Cnicus benedictus L. leaf extract: a mechanistic evaluation', Research in Pharmaceutical Sciences, 15(5), pp. 463-472. doi:10.4103/1735-5362.297849 Preclinical
    https://doi.org/10.4103/1735-5362.297849
  3. Zhang, J., Shen, S., Zhu, S., Jia, F. et al (2024) 'Cnicus benedictus extract-loaded electrospun gelatin wound dressing for treating diabetic wounds: An in vitro and in vivo study', Journal of Applied Biomaterials & Functional Materials, 22, pp. 22808000241245298. doi:10.1177/22808000241245298 Preclinical
    https://doi.org/10.1177/22808000241245298
  4. Zietal, K., Mirowska-Guzel, D., Nowaczyk, A. and Blecharz-Klin, K (2024) 'Cnicus benedictus: Folk Medicinal Uses, Biological Activities, and In Silico Screening of Main Phytochemical Constituents', Planta Medica. doi:10.1055/a-2401-6049 Traditional / reference
    https://doi.org/10.1055/a-2401-6049
  5. Jalil, D.M., Al-Mahdawi, T.T., Jameel, M.G. and Talal, M (2024) 'In Vitro Evaluate the Antiproliferative Impact of Cnicus Benedictus L. Leaves Methanolic Extract on Cervical Cancer', Asian Pacific Journal of Cancer Prevention, 25(10), pp. 3643-3649. doi:10.31557/APJCP.2024.25.10.3643 Preclinical
    https://doi.org/10.31557/APJCP.2024.25.10.3643
  6. Peng, Y., Jian, Y., Zulfiqar, A., Li, B., Zhang, K., Long, F., Peng, C., Cai, X., Khan, I.A. and Wang, W (2017) 'Two new sesquiterpene lactone glycosides from Cnicus benedictus', Natural Product Research, 31(19), pp. 2211-2217. doi:10.1080/14786419.2017.1295239 Preclinical
    https://doi.org/10.1080/14786419.2017.1295239
  7. Paun, G., Neagu, E., Moroeanu, V., Albu, C., Savin, S. and Lucian Radu, G (2019) 'Chemical and Bioactivity Evaluation of Cnicus benedictus and Eryngium planum Polyphenolic-Rich Extracts', BioMed Research International, 2019, pp. 3692605. doi:10.1155/2019/3692605 Preclinical
    https://doi.org/10.1155/2019/3692605
  8. Gobrecht, P., Gebel, J., Leibinger, M., Zeitler, C., Chen, Z., Grundemann, D. and Fischer, D (2024) 'Cnicin promotes functional nerve regeneration', Phytomedicine, 129, pp. 155641. doi:10.1016/j.phymed.2024.155641 Preclinical
    https://doi.org/10.1016/j.phymed.2024.155641
  9. Avula, B., Katragunta, K., Wang, Y.H., Ali, Z. and Khan, I.A (2022) 'Simultaneous determination and characterization of flavonoids, sesquiterpene lactone, and other phenolics from Centaurea benedicta and dietary supplements using UHPLC-PDA-MS and LC-DAD-QToF', Journal of Pharmaceutical and Biomedical Analysis, 216, pp. 114806. doi:10.1016/j.jpba.2022.114806 Preclinical
    https://doi.org/10.1016/j.jpba.2022.114806
  10. Paun, G., Neagu, E., Albu, C. and Radu, G.L (2015) 'Inhibitory potential of some Romanian medicinal plants against enzymes linked to neurodegenerative diseases and their antioxidant activity', Pharmacognosy Magazine, 11(Suppl 1), pp. S110-S116. doi:10.4103/0973-1296.157709 Preclinical
    https://doi.org/10.4103/0973-1296.157709
  11. Drugs.com (n.d.) 'Blessed Thistle Uses, Benefits & Dosage'. Available at: https://www.drugs.com/npp/blessed-thistle.html Traditional / reference
    https://www.drugs.com/npp/blessed-thistle.html
  12. Drugs and Lactation Database (LactMed) (2021) 'Blessed Thistle'. Available at: https://www.ncbi.nlm.nih.gov/books/NBK501775/ Traditional / reference
    https://www.ncbi.nlm.nih.gov/books/NBK501775/
  1. Kowalonek, J., Stachowiak, N., Bolczak, K. and Richert, A (2023) 'Physicochemical and Antibacterial Properties of Alginate Films Containing Tansy (Tanacetum vulgare L.) Essential Oil', Polymers, 15(2), pp. 260. doi:10.3390/polym15020260 Preclinical
    https://doi.org/10.3390/polym15020260
  2. Ak, G., Gevrenova, R., Sinan, K.I., Zengin, G. and others (2021) 'Tanacetum vulgare L. (Tansy) as an effective bioresource with promising pharmacological effects from natural arsenal', Food and Chemical Toxicology, 153, pp. 112268. doi:10.1016/j.fct.2021.112268 Preclinical
    https://doi.org/10.1016/j.fct.2021.112268
  3. Paderin, N.M., Saveliev, Y.N. and Popov, S.V (2020) 'The effect of pectin of tansy, Tanacetum vulgare L., on anxiety and overeating food rich in fats and sugars in mice in modelling binge eating', Voprosy Pitaniia, 89(6), pp. 14-22. doi:10.24411/0042-8833-2020-10074 Preclinical
    https://doi.org/10.24411/0042-8833-2020-10074
  4. Babich, O., Larina, V., Krol, O., Ulrikh, E. and others (2023) 'In Vitro Study of Biological Activity of Tanacetum vulgare Extracts', Pharmaceutics, 15(2), pp. 616. doi:10.3390/pharmaceutics15020616 Preclinical
    https://doi.org/10.3390/pharmaceutics15020616
  5. Puk, K. and Guz, L (2021) 'Parasiticidal effects of Tanacetum vulgare extract against Ichthyophthirius multifiliis', Polish Journal of Veterinary Sciences, 24(1), pp. 159-161. doi:10.24425/pjvs.2021.136805 Preclinical
    https://doi.org/10.24425/pjvs.2021.136805
  6. Roman, H., Niculescu, A.G., Lazar, V. and Mitache, M.M (2023) 'Antibacterial Efficiency of Tanacetum vulgare Essential Oil against ESKAPE Pathogens and Synergisms with Antibiotics', Antibiotics, 12(11), pp. 1635. doi:10.3390/antibiotics12111635 Preclinical
    https://doi.org/10.3390/antibiotics12111635
  7. Sukele, R., Lauberte, L., Kovalcuka, L., Logviss, K. and others (2023) 'Chemical Profiling and Antioxidant Activity of Tanacetum vulgare L. Wild-Growing in Latvia', Plants, 12(10), pp. 1968. doi:10.3390/plants12101968 Preclinical
    https://doi.org/10.3390/plants12101968
  8. Korpinen, R.I., Valimaa, A.L., Liimatainen, J. and Kunnas, S (2021) 'Essential Oils and Supercritical CO2 Extracts of Arctic Angelica, Marsh Labrador Tea and Common Tansy (Tanacetum vulgare)-Chemical Compositions and Antimicrobial Activities', Molecules, 26(23), pp. 7121. doi:10.3390/molecules26237121 Preclinical
    https://doi.org/10.3390/molecules26237121
  9. Jovanovic, M. and Poljacki, M (2003) 'Compositae dermatitis', Medicinski Pregled, 56(1-2), pp. 43-49. doi:10.2298/mpns0302043j Meta-analysis / review
    https://doi.org/10.2298/mpns0302043j
  10. Rohloff, J., Mordal, R. and Dragland, S (2004) 'Chemotypical variation of tansy (Tanacetum vulgare L.) from 40 different locations in Norway', Journal of Agricultural and Food Chemistry, 52(6), pp. 1742-1748. doi:10.1021/jf0352430 Preclinical
    https://doi.org/10.1021/jf0352430
  11. Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
    https://scholar.google.com/scholar?q=A%20Modern%20Herbal
  12. Kivilaan, A. and Bandurski, R.S (1981) 'The 1879 Beal seed viability experiment', 68(9), pp. 1290--1292. Traditional / reference
    https://scholar.google.com/scholar?q=The%201879%20Beal%20seed%20viability%20experiment
  13. Orav, A., Raal, A. and Arak, E (2006) 'Essential oil composition of Tanacetum vulgare L', 20(12), pp. 1129--1142. Traditional / reference
    https://scholar.google.com/scholar?q=Essential%20oil%20composition%20of%20Tanacetum%20vulgare%20L
  14. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  15. Washington State Noxious Weed Control Board 'Tansy Ragwort (Senecio jacobaea)'. Available at: https://www.nwcb.wa.gov/weeds/tansy-ragwort Traditional / reference
    https://www.nwcb.wa.gov/weeds/tansy-ragwort
  16. Schneider, J. and Tsegaye, Y. and W/Tensae, M. and G/Selassie, S. and Haile, T. and Bane, A. and Ali, A. and Mesfin, G. and Seboxa, T (2012) 'Veno-occlusive liver disease: a case report', Ethiopian Medical Journal, 50 Suppl 2, pp. 47-51. Available at: https://pubmed.ncbi.nlm.nih.gov/22946295/ Clinical study
    https://pubmed.ncbi.nlm.nih.gov/22946295/

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.