Plant Comparison

Birch vs Chamomile

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ABirchBetula pendulaBetulaceaeFull monograph →
Plant BChamomileMatricaria chamomillaAsteraceaeFull monograph →

At a glance

Birch and Chamomile: they share 9 indicated uses (arthritis / joint pain, back pain, blood sugar / diabetes support, …); 4 pharmacological actions in common.

BirchChamomile
Constituents34
Pharmacological actions1011
Indicated uses1618
Safety notes24
Cited sources1625
Indicated uses
Only Birch
Acid refluxCancer (anticancer research)Cold & fluMetabolic supportSwelling / fluid retentionUrinary supportUrinary tract infection (UTI)
Shared (9)
Arthritis / joint painBack painBlood sugar / diabetes supportEczemaIndigestionInfection (general)Inflammation (general)Skin irritationWounds
Only Chamomile
BloatingBruisingHeadacheInsomnia / sleeplessnessMenstrual crampsMuscle spasmPain (general)AnxietyLow mood / depression
Pharmacological actions
Only Birch
Anti-rheumatic / anti-arthriticAnticancer (preclinical)AntioxidantAntiviralDiureticGastroprotective
Shared (4)
Anti-inflammatoryAntidiabetic (blood-sugar lowering)AntimicrobialEmollient / skin-soothing
Only Chamomile
Analgesic (pain relief)AntispasmodicDigestive aidSedative / sleep supportVulnerary (wound healing)Anxiolytic / calmingAntidepressant / mood support

Evidence face-off — shared uses

ConditionBirchChamomileVerdict
Arthritis / joint pain1/105/10Stronger for Chamomile
Back pain1/101/10Comparable evidence
Blood sugar / diabetes support1/105/10Stronger for Chamomile
Eczema1/101/10Comparable evidence
Indigestion1/101/10Comparable evidence
Infection (general)1/101/10Comparable evidence
Inflammation (general)1/101/10Comparable evidence
Skin irritation1/101/10Comparable evidence
Wounds1/101/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Flavonoids (quercetin, myricetin, hyperoside)[1]

Principal diuretic and antioxidant constituents of the leaf.

FlavonoidsQuercetin
Triterpenes (betulin, betulinic acid)[1, 4]

Characteristic bark triterpenes, betulin giving birch bark its white colour; studied for anticancer and anti-inflammatory activity.

Terpenes / terpenoids
Tannins and phenolic acids[1]

Contribute to the astringent and antioxidant properties of the bark and leaf.

TanninsPhenolic acids
Essential oil (alpha-bisabolol, chamazulene)[1, 6]

The volatile oil, concentrated in the flower head, gives chamomile its characteristic blue colour (chamazulene) and much of its anti-inflammatory activity (alpha-bisabolol).

Essential (volatile) oilAlpha-bisabololChamazulene
Flavonoids (apigenin, quercetin, luteolin, rutin)[10]

Apigenin is considered a key contributor to chamomile's sedative/anxiolytic activity via GABA-A receptor binding.

ApigeninQuercetinLuteolinRutinFlavonoids
Coumarins[6]

Minor constituents (e.g. herniarin, umbelliferone) contributing to the mild antispasmodic action.

Coumarins
Mucilage polysaccharides[10]

Contribute to the soothing, demulcent effect on irritated mucous membranes.

MucilagePolysaccharides

Pharmacological Actions

Anti-inflammatory[1, 4, 7, 9, 13, 14, 15]
Anti-rheumatic / anti-arthritic[4, 13, 14, 15]
Anticancer (preclinical)[7, 8, 9, 13, 14, 15]
Antidiabetic (blood-sugar lowering)[6, 13, 14, 15]
Antimicrobial[1, 13, 14, 15]
Antioxidant[1, 2, 5, 6, 7, 13, 14, 15]
Antiviral[13, 14, 15]
Diuretic[13, 14, 15]
Emollient / skin-soothing[13, 14, 15]
Gastroprotective[13, 14, 15]
Analgesic (pain relief)[12, 14, 15, 16, 17, 18, 19]
Anti-inflammatory[1, 5, 6, 7, 10, 12, 15, 16, 17, 18, 19]
Antimicrobial[1, 15, 16, 17, 18, 19]
Antispasmodic[1, 5, 6, 14, 15, 16, 17, 18, 19]

Antispasmodic (cramp easing)

Digestive aid[1, 5, 10, 15, 16, 17, 18, 19]
Emollient / skin-soothing[15, 16, 17, 18, 19]
Sedative / sleep support[1, 2, 3, 4, 7, 8, 10, 15, 16, 17, 18, 19]
Vulnerary (wound healing)[15, 16, 17, 18, 19]
Anxiolytic / calming[3, 8]
Antidepressant / mood support[11]
Antidiabetic (blood-sugar lowering)[13]

Traditional & Indicated Uses

Acid reflux[13, 14, 15]Traditional · 1/10

inferred from gastroprotective action

Evidence: 1
Label: Acid reflux
Arthritis / joint pain[13, 14, 15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Back pain[13, 14, 15]Traditional · 1/10

inferred from anti-rheumatic action

Evidence: 1
Label: Back pain
Blood sugar / diabetes support[13, 14, 15]Traditional · 1/10

inferred from antidiabetic action

Evidence: 1
Label: Blood sugar / diabetes support
Cancer (anticancer research)[8]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Cold & flu[13, 14, 15]Traditional · 1/10

inferred from antiviral action

Evidence: 1
Label: Cold & flu
Eczema[13, 14, 15]Traditional · 1/10

inferred from emollient action

Evidence: 1
Label: Eczema
Indigestion[13, 14, 15]Traditional · 1/10

inferred from gastroprotective action

Evidence: 1
Label: Indigestion
Infection (general)[13, 14, 15]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[13, 14, 15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Metabolic support[13, 14, 15]Traditional · 1/10

inferred from antidiabetic action

Evidence: 1
Label: Metabolic support
Skin irritation[13, 14, 15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Swelling / fluid retention[13, 14, 15]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Swelling / fluid retention
Urinary support[13, 14, 15]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Urinary support
Urinary tract infection (UTI)[13, 14, 15]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Urinary tract infection (UTI)
Wounds[13, 14, 15]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Arthritis / joint pain[12, 15, 16, 17, 18, 19]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Arthritis / joint pain
Back pain[15, 16, 17, 18, 19]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Back pain
Bloating[15, 16, 17, 18, 19]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Bruising[15, 16, 17, 18, 19]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Eczema[15, 16, 17, 18, 19]Traditional · 1/10

inferred from emollient action

Evidence: 1
Label: Eczema
Headache[15, 16, 17, 18, 19]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Headache
Indigestion[15, 16, 17, 18, 19]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Indigestion
Infection (general)[15, 16, 17, 18, 19]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[15, 16, 17, 18, 19]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Insomnia / sleeplessness[2, 15, 16, 17, 18, 19]Good · 7/10

inferred from sedative action

Evidence: 7
Label: Insomnia / sleeplessness
Menstrual cramps[14, 15, 16, 17, 18, 19]Good · 7/10

inferred from antispasmodic action

Evidence: 7
Label: Menstrual cramps
Muscle spasm[15, 16, 17, 18, 19]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Muscle spasm
Pain (general)[15, 16, 17, 18, 19]Traditional · 1/10
Evidence: 1
Label: Pain (general)
Skin irritation[15, 16, 17, 18, 19]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[15, 16, 17, 18, 19]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Anxiety[3, 8]Moderate · 6/10
Evidence: 6
Label: Anxiety
Low mood / depression[11]Moderate · 5/10
Evidence: 5
Label: Low mood / depression
Blood sugar / diabetes support[13]Moderate · 5/10
Evidence: 5
Label: Blood sugar / diabetes support

Safety, Cautions & Contraindications

Safety note[13, 14, 15]Info

Generally considered safe when used appropriately. Side effects may include diarrhea, nausea, and allergic reactions (itching, rash, stuffy nose). Not recommended for individuals with edema caused by heart or kidney dysfunction. Ensure adequate fluid intake when using as a diuretic. Frequency of side effects is unknown.

Safety note[13, 14, 15, 16]Info

Duke (2002) provides clinical evidence (score 2) for birch leaf's diuretic activity, as well as for its use in urinary gravel, kidney stones, and rheumatic conditions — consistent with Commission E (KOM) and German Phytotherapy (PIP) approvals. It acts as an aquaretic, increasing urine volume without electrolyte loss. Antimelanomic activity has been demonstrated in experimental studies. The plant has a good safety profile and is classified as non-toxic at usual therapeutic doses (Duke, 2002).

Safety note[15, 16, 17, 18, 19]Caution

Generally considered very safe when used as tea or topical preparations.Allergy risk: People allergic to ragweed, daisies, or other Asteraceae plants may react (itching, rash).Blood thinners: Chamomile may slightly enhance effects of anticoagulants—use large amounts cautiously.Pregnancy: Normal tea amounts are usually considered safe, but concentrated extracts should be used with caution.Topical use: Rare skin irritation in sensitive individuals.

Safety note[15, 16, 17, 18, 19, 20]Caution

Duke (2002) rates German chamomile (Matricaria chamomilla) highly for anti-inflammatory, antispasmodic, and wound-healing activities. The essential oil contains the potent anti-inflammatory compound alpha-bisabolol. Chamomile is Commission E approved for digestive complaints and topical wound care. Dose: 3 g dried flower heads per cup of water, three times daily. Alpha-bisabolol is noted as one of the most active natural anti-inflammatory compounds known. Caution: chamomile belongs to the Asteraceae family and can cause allergic reactions in individuals sensitive to ragweed, chrysanthemums, or related plants (Duke, 2002).

Safety note[15, 16, 17, 18, 19]Caution

Generally very safe. Rare allergic reactions in individuals sensitive to the Asteraceae family (ragweed, chrysanthemums). May cause contact dermatitis with topical essential oil use. Avoid very high doses in pregnancy. Well tolerated by children in appropriate amounts.

Safety note[15, 16, 17, 18, 19, 20]Info

Scented mayweed (Matricaria chamomilla) shares the same species as German chamomile (see German Chamomile entry above). Duke (2002) provides the same clinical support: Commission E approves it for dyspeptic complaints (orally) and skin and mucous membrane inflammation (topically). Anti-inflammatory, antispasmodic, and wound-healing activities are well-established (Duke, 2002).

External Ids

Gbif: 5331916
Powo: urn:lsid:ipni.org:names:295174-1
Wikidata: Q156895
Gbif: 8370958
Wikidata: Q28437

Botanical Description

Elegant deciduous tree with a slender trunk, distinctive smooth white bark that peels in papery horizontal strips and becomes dark and fissured near the base with age, and characteristically drooping ('pendulous') branchlets. The leaves are small, triangular to diamond-shaped, doubly toothed and long-pointed. Male and female flowers are borne in separate catkins on the same tree in spring.[1]

Height: Up to 25-30 m
Habit: Slender deciduous tree with drooping branchlets
Leaves: Small, triangular to diamond-shaped, doubly toothed, long-pointed
Flowers: Separate male and female catkins on the same tree
Stem: Slender trunk with smooth white, papery, peeling bark, dark and fissured at the base with age
Root: Shallow, wide-spreading root system
Fruit: Tiny winged seed (samara) shed from the female catkin
Flowering Period: April-May

Aromatic annual herb, 15-60 cm tall, with an erect, much-branched, hairless stem. Leaves are alternate and finely bi- to tripinnately divided into thread-like segments, giving a feathery appearance. Flower heads are small daisy-like composites, 1-2.5 cm across, with white ray florets that reflex sharply downward as the flower matures around a conical, hollow, yellow disc of tubular florets - the hollow, conical receptacle is a key feature distinguishing German chamomile from similar-looking daisies. The fruit is a tiny ribbed achene without a pappus.[1, 10]

Height: 15-60 cm
Habit: Erect, much-branched, aromatic annual herb
Leaves: Alternate, finely 2-3-pinnately divided into thread-like segments
Flowers: Small daisy-like heads with downward-reflexed white ray florets around a conical hollow yellow disc
Stem: Erect, much-branched, hairless
Root: Slender taproot
Fruit: Tiny ribbed achene, no pappus
Flowering Period: May-August

Habitat

A pioneer tree of light, well-drained, often poor or acidic soils, growing in woodland, heathland and waste ground across Europe and much of temperate Asia.[1]

Native to Europe and western Asia and now naturalised worldwide, growing on disturbed, sunny ground - arable field margins, waste places, roadsides and sandy or loamy soils; widely cultivated as a medicinal crop.[1, 6]

Harvesting

Leaves are picked in spring and early summer while young and tender; bark is collected from felled or fallen wood (living trees should not be stripped of bark, which can kill them); sap is tapped in early spring, before leaf-out, through a small hole bored in the trunk.[1]

Parts: Bark, Leaf, Sap
Season: Leaf in spring/early summer; sap in early spring before leaf-out; bark from felled wood

Flower heads are hand- or machine-harvested at full bloom, when the ray florets are horizontal and just beginning to reflex, then dried quickly at low temperature and out of direct light to preserve the volatile oil.[6]

Parts: Flower heads
Season: Late spring to summer, at full bloom

Traditional Uses

Birch leaf is a classic European 'aquaretic' diuretic used for urinary gravel, kidney stones and as a spring detoxifying tonic, and for rheumatic and joint complaints; the bark and its extracts have a long folk history for skin conditions, while the sap has been drunk fresh as a traditional spring tonic.[1]

Chamomile is one of the most widely used medicinal herbs in the world, with a long traditional history as a mild digestive, calming and anti-inflammatory remedy - taken as a tea for indigestion, cramping, and restlessness or poor sleep, and applied topically for skin and mucous-membrane inflammation and wound healing. Modern reviews confirm anti-inflammatory, antispasmodic, sedative/anxiolytic and antimicrobial pharmacological activity supporting these traditional uses.[1, 6, 10]

Preparations

Infusion (leaf)[1]

Dried leaf infused in hot water as a traditional diuretic and 'detox' tea, classically taken as a course in spring.

Decoction (bark)[1]

Bark simmered in water or processed into extracts for topical skin use.

Infusion (tea)[6, 10]

Dried flower heads steeped in hot water, the classic way of taking chamomile for digestive complaints, mild anxiety and sleep support.

Essential oil[1]

Steam-distilled from the flower heads; a concentrated source of alpha-bisabolol and chamazulene, used mainly in topical and aromatherapy preparations.

Topical cream/compress[12]

Concentrated extract or infused oil applied to skin, or as a compress - a randomised controlled trial found a topical chamomile oil preparation effective for knee osteoarthritis pain.

Dosage

Leaf infusion[12, 13]

The EU herbal monograph gives 2-3 g of the comminuted leaf in 150 mL of boiling water as an infusion, up to 4 times daily, in adolescents, adults and elderly, with adequate fluid intake; dry extract at 0.25-1 g 4 times daily and liquid extract at 15 mL 2-3 times daily are also listed. Traditionally used over a period of 2-4 weeks. Not recommended under 12 years. Educational reference only, not a prescription.

Infusion (tea)[15, 16, 17, 18, 19]

Traditional guidance and Duke (2002) suggest about 3 g of dried flower heads per cup of water, taken up to three times daily. Educational reference only, not a prescription.

References

REF-0743, REF-0744, REF-0745, REF-1692, REF-1693, REF-1694, REF-1695, REF-1696, REF-1697, REF-1698, REF-1699
REF-1153, REF-1154, REF-1155, REF-1156, REF-1157, REF-1158, REF-1159, REF-1160, REF-1161, REF-1162, REF-2348, REF-2349, REF-2350, REF-2351

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Drug Class Interactions

Not documented

Safety note[21]Caution
Drug Class: anticoagulants-antiplatelets
Mechanism: Chamomile contains natural coumarin constituents and has been linked in a case report to increased bleeding when taken with warfarin, so caution is advised when combining it with anticoagulant or antiplatelet drugs.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Safety note[22, 23, 24]Caution
Drug Class: sedatives-cns-depressants
Mechanism: Chamomile has calming, sedative effects (a randomised controlled trial found it reduces generalised-anxiety symptoms); taken with sedatives, sleeping tablets or other central-nervous-system depressants (including alcohol) it may add to drowsiness and slowed reactions.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Safety note[25]Caution
Drug Class: antidiabetics
Mechanism: Chamomile improved blood-sugar control (lower HbA1c and insulin resistance) in a trial in type 2 diabetes; combined with diabetes medicines it may add to blood-sugar lowering, so monitor blood sugar.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Pairings

Not documented

Chamomile and valerian are both traditional mild sedatives for restlessness and poor sleep; taken together they may enhance calming and sleep effects but also add to drowsiness.[23]

Partner Id: valeriana-officinalis
Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Chamomile and lemon balm are both gentle calming herbs commonly combined for stress and sleep; used together their mild sedative effects may add up.[23]

Partner Id: melissa-officinalis
Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Chamomile and passionflower are both gentle calming, sleep-supporting herbs traditionally combined; used together they may reinforce each other's soothing, sleep-promoting effect.[22, 23]

Partner Id: passiflora-incarnata
Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

References & Sources

  1. Rastogi, S., Pandey, M.M. and Kumar Singh Rawat, A (2014) 'Medicinal plants of the genus Betula — traditional uses and a phytochemical-pharmacological review', Journal of Ethnopharmacology, 159, pp. 62-83. doi:10.1016/j.jep.2014.11.010 Traditional / reference
    https://doi.org/10.1016/j.jep.2014.11.010
  2. Penkov, D., Andonova, V., Delev, D. and Kostadinov, I (2018) 'Antioxidant Activity of Dry Birch (Betula pendula) Leaves Extract', Folia Medica, 60(4), pp. 571-579. doi:10.2478/folmed-2018-0035 Preclinical
    https://doi.org/10.2478/folmed-2018-0035
  3. Sevastre-Berghian, A.C., Ielciu, I., Bab, T., Olah, N.K. et al (2023) 'Betula pendula Leaf Extract Targets the Interplay between Brain Oxidative Stress, Inflammation, and NF-kB Pathways in Amyloid Abeta-Treated Rats', Antioxidants (Basel), 12(12), pp. 2110. doi:10.3390/antiox12122110 Preclinical
    https://doi.org/10.3390/antiox12122110
  4. Grundemann, C., Gruber, C.W., Hertrampf, A., Zehl, M., Kopp, B. and Huber, R (2011) 'An aqueous birch leaf extract of Betula pendula inhibits the growth and cell division of inflammatory lymphocytes', Journal of Ethnopharmacology, 136(3), pp. 444-451. doi:10.1016/j.jep.2011.05.018 Preclinical
    https://doi.org/10.1016/j.jep.2011.05.018
  5. Azman, N.A.M., Skowyra, M., Muhammad, K., Gallego, M.G. and Almajano, M.P (2017) 'Evaluation of the antioxidant activity of Betula pendula leaves extract and its effects on model foods', Pharmaceutical Biology, 55(1), pp. 912-919. doi:10.1080/13880209.2017.1282528 Preclinical
    https://doi.org/10.1080/13880209.2017.1282528
  6. Bljajic, K., Sostaric, N., Petlevski, R., Vujic, L., Brajkovic, A. and Fumic, B (2016) 'Effect of Betula pendula Leaf Extract on alpha-Glucosidase and Glutathione Level in Glucose-Induced Oxidative Stress', Evidence-Based Complementary and Alternative Medicine, 2016, pp. 8429398. doi:10.1155/2016/8429398 Preclinical
    https://doi.org/10.1155/2016/8429398
  7. Ou-Yang, T., Zhang, Y., Luo, H.Z., Liu, Y. and Ma, S.C (2023) 'Novel compounds discovery approach based on UPLC-QTOF-MS/MS chemical profile reveals birch bark extract anti-inflammatory, -oxidative, and -proliferative effects', Journal of Ethnopharmacology, 309, pp. 116148. doi:10.1016/j.jep.2023.116148 Preclinical
    https://doi.org/10.1016/j.jep.2023.116148
  8. Szoka, L., Nazaruk, J., Stocki, M. and Isidorov, V (2021) 'Santin and cirsimaritin from Betula pubescens and Betula pendula buds induce apoptosis in human digestive system cancer cells', Journal of Cellular and Molecular Medicine, 25(23), pp. 11085-11096. doi:10.1111/jcmm.17031 Preclinical
    https://doi.org/10.1111/jcmm.17031
  9. Isidorov, V., Szoka, L. and Nazaruk, J (2018) 'Cytotoxicity of white birch bud extracts: Perspectives for therapy of tumours', PLoS One, 13(8), pp. e0201949. doi:10.1371/journal.pone.0201949 Preclinical
    https://doi.org/10.1371/journal.pone.0201949
  10. Efthimiou, I., Vlastos, D., Triantafyllidis, V., Eleftherianos, A. and Antonopoulou, M (2022) 'Investigation of the Genotoxicological Profile of Aqueous Betula pendula Extracts', Plants, 11(20), pp. 2673. doi:10.3390/plants11202673 Preclinical
    https://doi.org/10.3390/plants11202673
  11. Jafari Hajati, R., Payamnoor, V., Ahmadian Chashmi, N. and Ghasemi Bezdi, K (2018) 'Improved accumulation of betulin and betulinic acid in cell suspension culture of Betula pendula Roth by abiotic and biotic elicitors', Preparative Biochemistry & Biotechnology, 48(10), pp. 915-924. doi:10.1080/10826068.2018.1514514 Preclinical
    https://doi.org/10.1080/10826068.2018.1514514
  12. European Medicines Agency (HMPC) (2015) 'European Union herbal monograph on Betula pendula Roth and/or Betula pubescens Ehrh. as well as hybrids of both species, folium'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-betula-pendula-roth-betula-pubescens-ehrh-folium_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-betula-pendula-roth-betula-pubescens-ehrh-folium_en.pdf
  13. European Medicines Agency (HMPC) (2015) 'Birch leaf (Betulae folium): summary for the public'. Available at: https://www.ema.europa.eu/en/documents/herbal-summary/birch-leaf-summary-public_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/herbal-summary/birch-leaf-summary-public_en.pdf
  14. Oszmiański J, et al. Evaluating birch leaf tea as a functional herbal beverage. Food Res Int. 2024. https://www.sciencedirect.com/science/article/abs/pii/S0963996924005519 https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/ (2024) 'https://www.sciencedirect.com/science/article/abs/pii/S0963996924005519 https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/'. Available at: https://www.sciencedirect.com/science/article/abs/pii/S0963996924005519 Traditional / reference
    https://www.sciencedirect.com/science/article/abs/pii/S0963996924005519
  15. Rastogi S, Pandey MM, Rawat AKS. Medicinal plants of the genus Betula—Traditional uses and a phytochemical–pharmacological review. J Ethnopharmacol. 2015;159:62-83. https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/ (2015) ';159:62-83'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/
  16. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  1. El Mihyaoui, A., Esteves da Silva, J.C.G., Charfi, S., Candela Castillo, M.E. and others (2022) 'Chamomile (Matricaria chamomilla L.): A Review of Ethnomedicinal Use, Phytochemistry and Pharmacological Uses', Life, 12(4), pp. 479. doi:10.3390/life12040479 Meta-analysis / review
    https://doi.org/10.3390/life12040479
  2. Kazemi, A., Shojaei-Zarghani, S., Eskandarzadeh, P. and Hashempur, M.H (2024) 'Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials', Complementary Therapies in Medicine, 84, pp. 103071. doi:10.1016/j.ctim.2024.103071 Meta-analysis / review
    https://doi.org/10.1016/j.ctim.2024.103071
  3. Mao, J.J., Xie, S.X., Keefe, J.R., Soeller, I. and others (2016) 'Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial', Phytomedicine, 23(14), pp. 1735-1742. doi:10.1016/j.phymed.2016.10.012 Randomized trial
    https://doi.org/10.1016/j.phymed.2016.10.012
  4. Amsterdam, J.D., Li, Q.S., Xie, S.X. and Mao, J.J (2020) 'Putative Antidepressant Effect of Chamomile (Matricaria chamomilla L.) Oral Extract in Subjects with Comorbid Generalized Anxiety Disorder and Depression', Journal of Alternative and Complementary Medicine, 26(9), pp. 813-819. doi:10.1089/acm.2019.0252 Clinical study
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  5. McKay, D.L. and Blumberg, J.B (2006) 'A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.)', Phytotherapy Research, 20(7), pp. 519-530. doi:10.1002/ptr.1900 Meta-analysis / review
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  6. Dai, Y.L., Li, Y., Wang, Q., Niu, F.J. and others (2022) 'Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies', Molecules, 28(1), pp. 133. doi:10.3390/molecules28010133 Meta-analysis / review
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  7. Miraj, S. and Alesaeidi, S (2016) 'A systematic review study of therapeutic effects of Matricaria recutita chamomile (chamomile)', Electronic Physician, 8(9), pp. 3024-3031. doi:10.19082/3024 Meta-analysis / review
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  8. Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K. and others (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
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  9. Park, S.H., Kim, D.S., Oh, J., Geum, J.H. and others (2021) 'Matricaria chamomilla (Chamomile) Ameliorates Muscle Atrophy in Mice by Targeting Protein Catalytic Pathways, Myogenesis, and Mitochondrial Dysfunction', The American Journal of Chinese Medicine, 49(6), pp. 1493-1514. doi:10.1142/S0192415X21500701 Preclinical
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  10. Singh, O., Khanam, Z., Misra, N. and Srivastava, M.K (2011) 'Chamomile (Matricaria chamomilla L.): An overview', Pharmacognosy Reviews, 5(9), pp. 82-95. doi:10.4103/0973-7847.79103 Meta-analysis / review
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  11. Amsterdam, J.D., Shults, J., Soeller, I., Mao, J.J., Rockwell, K. and Newberg, A.B (2012) 'Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study', Alternative Therapies in Health and Medicine, 18(5), pp. 44-49. Randomized trial
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  12. Shoara, R., Hashempur, M.H., Ashraf, A., Salehi, A., Dehshahri, S. and Habibagahi, Z (2015) 'Efficacy and safety of topical Matricaria chamomilla L. (chamomile) oil for knee osteoarthritis: a randomized controlled clinical trial', Complementary Therapies in Clinical Practice, 21(3), pp. 181-187. doi:10.1016/j.ctcp.2015.06.003 Randomized trial
    https://doi.org/10.1016/j.ctcp.2015.06.003
  13. Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2016) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
    https://doi.org/10.1016/j.nut.2015.07.011
  14. Niazi, A. and Moradi, M (2021) 'The effect of chamomile on pain and menstrual bleeding in primary dysmenorrhea: a systematic review', International Journal of Community Based Nursing and Midwifery, 9(3), pp. 174-186. doi:10.30476/ijcbnm.2021.87219.1417 Meta-analysis / review
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  15. European Medicines Agency (2015) 'European Union herbal monograph on Matricaria recutita L., flos'. Traditional / reference
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  22. Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
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  23. Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
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  24. Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K., Mao, J.J. and Shults, J (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
    https://doi.org/10.1097/JCP.0b013e3181ac935c
  25. Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2015) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.