Plant Comparison
Birch vs Chamomile
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Birch and Chamomile: they share 9 indicated uses (arthritis / joint pain, back pain, blood sugar / diabetes support, …); 4 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Birch | Chamomile | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 5/10 | Stronger for Chamomile |
| Back pain | 1/10 | 1/10 | Comparable evidence |
| Blood sugar / diabetes support | 1/10 | 5/10 | Stronger for Chamomile |
| Eczema | 1/10 | 1/10 | Comparable evidence |
| Indigestion | 1/10 | 1/10 | Comparable evidence |
| Infection (general) | 1/10 | 1/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
| Wounds | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Principal diuretic and antioxidant constituents of the leaf.
Characteristic bark triterpenes, betulin giving birch bark its white colour; studied for anticancer and anti-inflammatory activity.
Contribute to the astringent and antioxidant properties of the bark and leaf.
The volatile oil, concentrated in the flower head, gives chamomile its characteristic blue colour (chamazulene) and much of its anti-inflammatory activity (alpha-bisabolol).
Apigenin is considered a key contributor to chamomile's sedative/anxiolytic activity via GABA-A receptor binding.
Minor constituents (e.g. herniarin, umbelliferone) contributing to the mild antispasmodic action.
Contribute to the soothing, demulcent effect on irritated mucous membranes.
Pharmacological Actions
Traditional & Indicated Uses
inferred from gastroprotective action
inferred from anti-inflammatory action
inferred from anti-rheumatic action
inferred from antidiabetic action
inferred from anticancer action
inferred from gastroprotective action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from antidiabetic action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
inferred from anti-inflammatory action
inferred from analgesic action
inferred from digestive action
inferred from vulnerary action
inferred from analgesic action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from sedative action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from antimicrobial action
Safety, Cautions & Contraindications
Generally considered safe when used appropriately. Side effects may include diarrhea, nausea, and allergic reactions (itching, rash, stuffy nose). Not recommended for individuals with edema caused by heart or kidney dysfunction. Ensure adequate fluid intake when using as a diuretic. Frequency of side effects is unknown.
Duke (2002) provides clinical evidence (score 2) for birch leaf's diuretic activity, as well as for its use in urinary gravel, kidney stones, and rheumatic conditions — consistent with Commission E (KOM) and German Phytotherapy (PIP) approvals. It acts as an aquaretic, increasing urine volume without electrolyte loss. Antimelanomic activity has been demonstrated in experimental studies. The plant has a good safety profile and is classified as non-toxic at usual therapeutic doses (Duke, 2002).
Generally considered very safe when used as tea or topical preparations.Allergy risk: People allergic to ragweed, daisies, or other Asteraceae plants may react (itching, rash).Blood thinners: Chamomile may slightly enhance effects of anticoagulants—use large amounts cautiously.Pregnancy: Normal tea amounts are usually considered safe, but concentrated extracts should be used with caution.Topical use: Rare skin irritation in sensitive individuals.
Duke (2002) rates German chamomile (Matricaria chamomilla) highly for anti-inflammatory, antispasmodic, and wound-healing activities. The essential oil contains the potent anti-inflammatory compound alpha-bisabolol. Chamomile is Commission E approved for digestive complaints and topical wound care. Dose: 3 g dried flower heads per cup of water, three times daily. Alpha-bisabolol is noted as one of the most active natural anti-inflammatory compounds known. Caution: chamomile belongs to the Asteraceae family and can cause allergic reactions in individuals sensitive to ragweed, chrysanthemums, or related plants (Duke, 2002).
Generally very safe. Rare allergic reactions in individuals sensitive to the Asteraceae family (ragweed, chrysanthemums). May cause contact dermatitis with topical essential oil use. Avoid very high doses in pregnancy. Well tolerated by children in appropriate amounts.
Scented mayweed (Matricaria chamomilla) shares the same species as German chamomile (see German Chamomile entry above). Duke (2002) provides the same clinical support: Commission E approves it for dyspeptic complaints (orally) and skin and mucous membrane inflammation (topically). Anti-inflammatory, antispasmodic, and wound-healing activities are well-established (Duke, 2002).
External Ids
Botanical Description
Elegant deciduous tree with a slender trunk, distinctive smooth white bark that peels in papery horizontal strips and becomes dark and fissured near the base with age, and characteristically drooping ('pendulous') branchlets. The leaves are small, triangular to diamond-shaped, doubly toothed and long-pointed. Male and female flowers are borne in separate catkins on the same tree in spring.[1]
Aromatic annual herb, 15-60 cm tall, with an erect, much-branched, hairless stem. Leaves are alternate and finely bi- to tripinnately divided into thread-like segments, giving a feathery appearance. Flower heads are small daisy-like composites, 1-2.5 cm across, with white ray florets that reflex sharply downward as the flower matures around a conical, hollow, yellow disc of tubular florets - the hollow, conical receptacle is a key feature distinguishing German chamomile from similar-looking daisies. The fruit is a tiny ribbed achene without a pappus.[1, 10]
Habitat
A pioneer tree of light, well-drained, often poor or acidic soils, growing in woodland, heathland and waste ground across Europe and much of temperate Asia.[1]
Harvesting
Leaves are picked in spring and early summer while young and tender; bark is collected from felled or fallen wood (living trees should not be stripped of bark, which can kill them); sap is tapped in early spring, before leaf-out, through a small hole bored in the trunk.[1]
Flower heads are hand- or machine-harvested at full bloom, when the ray florets are horizontal and just beginning to reflex, then dried quickly at low temperature and out of direct light to preserve the volatile oil.[6]
Traditional Uses
Birch leaf is a classic European 'aquaretic' diuretic used for urinary gravel, kidney stones and as a spring detoxifying tonic, and for rheumatic and joint complaints; the bark and its extracts have a long folk history for skin conditions, while the sap has been drunk fresh as a traditional spring tonic.[1]
Chamomile is one of the most widely used medicinal herbs in the world, with a long traditional history as a mild digestive, calming and anti-inflammatory remedy - taken as a tea for indigestion, cramping, and restlessness or poor sleep, and applied topically for skin and mucous-membrane inflammation and wound healing. Modern reviews confirm anti-inflammatory, antispasmodic, sedative/anxiolytic and antimicrobial pharmacological activity supporting these traditional uses.[1, 6, 10]
Preparations
Dried flower heads steeped in hot water, the classic way of taking chamomile for digestive complaints, mild anxiety and sleep support.
Steam-distilled from the flower heads; a concentrated source of alpha-bisabolol and chamazulene, used mainly in topical and aromatherapy preparations.
Concentrated extract or infused oil applied to skin, or as a compress - a randomised controlled trial found a topical chamomile oil preparation effective for knee osteoarthritis pain.
Dosage
The EU herbal monograph gives 2-3 g of the comminuted leaf in 150 mL of boiling water as an infusion, up to 4 times daily, in adolescents, adults and elderly, with adequate fluid intake; dry extract at 0.25-1 g 4 times daily and liquid extract at 15 mL 2-3 times daily are also listed. Traditionally used over a period of 2-4 weeks. Not recommended under 12 years. Educational reference only, not a prescription.
References
Lookalikes Review
Drug Class Interactions
Not documented
Pairings
Not documented
Chamomile and valerian are both traditional mild sedatives for restlessness and poor sleep; taken together they may enhance calming and sleep effects but also add to drowsiness.[23]
Chamomile and lemon balm are both gentle calming herbs commonly combined for stress and sleep; used together their mild sedative effects may add up.[23]
References & Sources
- Rastogi, S., Pandey, M.M. and Kumar Singh Rawat, A (2014) 'Medicinal plants of the genus Betula — traditional uses and a phytochemical-pharmacological review', Journal of Ethnopharmacology, 159, pp. 62-83. doi:10.1016/j.jep.2014.11.010 Traditional / reference
https://doi.org/10.1016/j.jep.2014.11.010 - Penkov, D., Andonova, V., Delev, D. and Kostadinov, I (2018) 'Antioxidant Activity of Dry Birch (Betula pendula) Leaves Extract', Folia Medica, 60(4), pp. 571-579. doi:10.2478/folmed-2018-0035 Preclinical
https://doi.org/10.2478/folmed-2018-0035 - Sevastre-Berghian, A.C., Ielciu, I., Bab, T., Olah, N.K. et al (2023) 'Betula pendula Leaf Extract Targets the Interplay between Brain Oxidative Stress, Inflammation, and NF-kB Pathways in Amyloid Abeta-Treated Rats', Antioxidants (Basel), 12(12), pp. 2110. doi:10.3390/antiox12122110 Preclinical
https://doi.org/10.3390/antiox12122110 - Grundemann, C., Gruber, C.W., Hertrampf, A., Zehl, M., Kopp, B. and Huber, R (2011) 'An aqueous birch leaf extract of Betula pendula inhibits the growth and cell division of inflammatory lymphocytes', Journal of Ethnopharmacology, 136(3), pp. 444-451. doi:10.1016/j.jep.2011.05.018 Preclinical
https://doi.org/10.1016/j.jep.2011.05.018 - Azman, N.A.M., Skowyra, M., Muhammad, K., Gallego, M.G. and Almajano, M.P (2017) 'Evaluation of the antioxidant activity of Betula pendula leaves extract and its effects on model foods', Pharmaceutical Biology, 55(1), pp. 912-919. doi:10.1080/13880209.2017.1282528 Preclinical
https://doi.org/10.1080/13880209.2017.1282528 - Bljajic, K., Sostaric, N., Petlevski, R., Vujic, L., Brajkovic, A. and Fumic, B (2016) 'Effect of Betula pendula Leaf Extract on alpha-Glucosidase and Glutathione Level in Glucose-Induced Oxidative Stress', Evidence-Based Complementary and Alternative Medicine, 2016, pp. 8429398. doi:10.1155/2016/8429398 Preclinical
https://doi.org/10.1155/2016/8429398 - Ou-Yang, T., Zhang, Y., Luo, H.Z., Liu, Y. and Ma, S.C (2023) 'Novel compounds discovery approach based on UPLC-QTOF-MS/MS chemical profile reveals birch bark extract anti-inflammatory, -oxidative, and -proliferative effects', Journal of Ethnopharmacology, 309, pp. 116148. doi:10.1016/j.jep.2023.116148 Preclinical
https://doi.org/10.1016/j.jep.2023.116148 - Szoka, L., Nazaruk, J., Stocki, M. and Isidorov, V (2021) 'Santin and cirsimaritin from Betula pubescens and Betula pendula buds induce apoptosis in human digestive system cancer cells', Journal of Cellular and Molecular Medicine, 25(23), pp. 11085-11096. doi:10.1111/jcmm.17031 Preclinical
https://doi.org/10.1111/jcmm.17031 - Isidorov, V., Szoka, L. and Nazaruk, J (2018) 'Cytotoxicity of white birch bud extracts: Perspectives for therapy of tumours', PLoS One, 13(8), pp. e0201949. doi:10.1371/journal.pone.0201949 Preclinical
https://doi.org/10.1371/journal.pone.0201949 - Efthimiou, I., Vlastos, D., Triantafyllidis, V., Eleftherianos, A. and Antonopoulou, M (2022) 'Investigation of the Genotoxicological Profile of Aqueous Betula pendula Extracts', Plants, 11(20), pp. 2673. doi:10.3390/plants11202673 Preclinical
https://doi.org/10.3390/plants11202673 - Jafari Hajati, R., Payamnoor, V., Ahmadian Chashmi, N. and Ghasemi Bezdi, K (2018) 'Improved accumulation of betulin and betulinic acid in cell suspension culture of Betula pendula Roth by abiotic and biotic elicitors', Preparative Biochemistry & Biotechnology, 48(10), pp. 915-924. doi:10.1080/10826068.2018.1514514 Preclinical
https://doi.org/10.1080/10826068.2018.1514514 - European Medicines Agency (HMPC) (2015) 'European Union herbal monograph on Betula pendula Roth and/or Betula pubescens Ehrh. as well as hybrids of both species, folium'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-betula-pendula-roth-betula-pubescens-ehrh-folium_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-betula-pendula-roth-betula-pubescens-ehrh-folium_en.pdf - European Medicines Agency (HMPC) (2015) 'Birch leaf (Betulae folium): summary for the public'. Available at: https://www.ema.europa.eu/en/documents/herbal-summary/birch-leaf-summary-public_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-summary/birch-leaf-summary-public_en.pdf - Oszmiański J, et al. Evaluating birch leaf tea as a functional herbal beverage. Food Res Int. 2024. https://www.sciencedirect.com/science/article/abs/pii/S0963996924005519 https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/ (2024) 'https://www.sciencedirect.com/science/article/abs/pii/S0963996924005519 https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/'. Available at: https://www.sciencedirect.com/science/article/abs/pii/S0963996924005519 Traditional / reference
https://www.sciencedirect.com/science/article/abs/pii/S0963996924005519 - Rastogi S, Pandey MM, Rawat AKS. Medicinal plants of the genus Betula—Traditional uses and a phytochemical–pharmacological review. J Ethnopharmacol. 2015;159:62-83. https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/ (2015) ';159:62-83'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/ Traditional / reference
https://pmc.ncbi.nlm.nih.gov/articles/PMC7126499/ - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
- El Mihyaoui, A., Esteves da Silva, J.C.G., Charfi, S., Candela Castillo, M.E. and others (2022) 'Chamomile (Matricaria chamomilla L.): A Review of Ethnomedicinal Use, Phytochemistry and Pharmacological Uses', Life, 12(4), pp. 479. doi:10.3390/life12040479 Meta-analysis / review
https://doi.org/10.3390/life12040479 - Kazemi, A., Shojaei-Zarghani, S., Eskandarzadeh, P. and Hashempur, M.H (2024) 'Effects of chamomile (Matricaria chamomilla L.) on sleep: A systematic review and meta-analysis of clinical trials', Complementary Therapies in Medicine, 84, pp. 103071. doi:10.1016/j.ctim.2024.103071 Meta-analysis / review
https://doi.org/10.1016/j.ctim.2024.103071 - Mao, J.J., Xie, S.X., Keefe, J.R., Soeller, I. and others (2016) 'Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial', Phytomedicine, 23(14), pp. 1735-1742. doi:10.1016/j.phymed.2016.10.012 Randomized trial
https://doi.org/10.1016/j.phymed.2016.10.012 - Amsterdam, J.D., Li, Q.S., Xie, S.X. and Mao, J.J (2020) 'Putative Antidepressant Effect of Chamomile (Matricaria chamomilla L.) Oral Extract in Subjects with Comorbid Generalized Anxiety Disorder and Depression', Journal of Alternative and Complementary Medicine, 26(9), pp. 813-819. doi:10.1089/acm.2019.0252 Clinical study
https://doi.org/10.1089/acm.2019.0252 - McKay, D.L. and Blumberg, J.B (2006) 'A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.)', Phytotherapy Research, 20(7), pp. 519-530. doi:10.1002/ptr.1900 Meta-analysis / review
https://doi.org/10.1002/ptr.1900 - Dai, Y.L., Li, Y., Wang, Q., Niu, F.J. and others (2022) 'Chamomile: A Review of Its Traditional Uses, Chemical Constituents, Pharmacological Activities and Quality Control Studies', Molecules, 28(1), pp. 133. doi:10.3390/molecules28010133 Meta-analysis / review
https://doi.org/10.3390/molecules28010133 - Miraj, S. and Alesaeidi, S (2016) 'A systematic review study of therapeutic effects of Matricaria recutita chamomile (chamomile)', Electronic Physician, 8(9), pp. 3024-3031. doi:10.19082/3024 Meta-analysis / review
https://doi.org/10.19082/3024 - Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K. and others (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
https://doi.org/10.1097/JCP.0b013e3181ac935c - Park, S.H., Kim, D.S., Oh, J., Geum, J.H. and others (2021) 'Matricaria chamomilla (Chamomile) Ameliorates Muscle Atrophy in Mice by Targeting Protein Catalytic Pathways, Myogenesis, and Mitochondrial Dysfunction', The American Journal of Chinese Medicine, 49(6), pp. 1493-1514. doi:10.1142/S0192415X21500701 Preclinical
https://doi.org/10.1142/S0192415X21500701 - Singh, O., Khanam, Z., Misra, N. and Srivastava, M.K (2011) 'Chamomile (Matricaria chamomilla L.): An overview', Pharmacognosy Reviews, 5(9), pp. 82-95. doi:10.4103/0973-7847.79103 Meta-analysis / review
https://doi.org/10.4103/0973-7847.79103 - Amsterdam, J.D., Shults, J., Soeller, I., Mao, J.J., Rockwell, K. and Newberg, A.B (2012) 'Chamomile (Matricaria recutita) may provide antidepressant activity in anxious, depressed humans: an exploratory study', Alternative Therapies in Health and Medicine, 18(5), pp. 44-49. Randomized trial
https://scholar.google.com/scholar?q=Chamomile%20%28Matricaria%20recutita%29%20may%20provide%20antidepressant%20activity%20in%20anxious%2C%20depressed%20humans%3A%20an%20exploratory%20study - Shoara, R., Hashempur, M.H., Ashraf, A., Salehi, A., Dehshahri, S. and Habibagahi, Z (2015) 'Efficacy and safety of topical Matricaria chamomilla L. (chamomile) oil for knee osteoarthritis: a randomized controlled clinical trial', Complementary Therapies in Clinical Practice, 21(3), pp. 181-187. doi:10.1016/j.ctcp.2015.06.003 Randomized trial
https://doi.org/10.1016/j.ctcp.2015.06.003 - Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2016) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
https://doi.org/10.1016/j.nut.2015.07.011 - Niazi, A. and Moradi, M (2021) 'The effect of chamomile on pain and menstrual bleeding in primary dysmenorrhea: a systematic review', International Journal of Community Based Nursing and Midwifery, 9(3), pp. 174-186. doi:10.30476/ijcbnm.2021.87219.1417 Meta-analysis / review
https://doi.org/10.30476/ijcbnm.2021.87219.1417 - European Medicines Agency (2015) 'European Union herbal monograph on Matricaria recutita L., flos'. Traditional / reference
https://scholar.google.com/scholar?q=European%20Union%20herbal%20monograph%20on%20Matricaria%20recutita%20L.%2C%20flos - Hoffmann, D (2003) 'Medical Herbalism'. Traditional / reference
https://scholar.google.com/scholar?q=Medical%20Herbalism - Padula, M.C (2006) 'Chamomile: industrial profiles'. Traditional / reference
https://scholar.google.com/scholar?q=Chamomile%3A%20industrial%20profiles - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Srivastava, J.K., Shankar, E. and Gupta, S (2010) 'Chamomile: a herbal medicine of the past with bright future', 3(6), pp. 895--901. doi:10.3892/mmr.2010.377 Traditional / reference
https://doi.org/10.3892/mmr.2010.377 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Segal, R. and Pilote, L (2006) 'Warfarin interaction with Matricaria chamomilla', CMAJ, 174(9), pp. 1281-1282. doi:10.1503/cmaj.051191 Clinical study
https://doi.org/10.1503/cmaj.051191 - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003 - Amsterdam, J.D., Li, Y., Soeller, I., Rockwell, K., Mao, J.J. and Shults, J (2009) 'A randomized, double-blind, placebo-controlled trial of oral Matricaria recutita (chamomile) extract therapy for generalized anxiety disorder', Journal of Clinical Psychopharmacology, 29(4), pp. 378-382. doi:10.1097/JCP.0b013e3181ac935c Randomized trial
https://doi.org/10.1097/JCP.0b013e3181ac935c - Zemestani, M., Rafraf, M. and Asghari-Jafarabadi, M (2015) 'Chamomile tea improves glycemic indices and antioxidants status in patients with type 2 diabetes mellitus', Nutrition, 32(1), pp. 66-72. doi:10.1016/j.nut.2015.07.011 Randomized trial
https://doi.org/10.1016/j.nut.2015.07.011
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.