Omnia SanaPlant Comparison
Dill vs Marjoram
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Dill and Marjoram: they share 7 indicated uses (arthritis / joint pain, bloating, indigestion, …); 4 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Dill | Marjoram | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 8/10 | 1/10 | Stronger for Dill |
| Bloating | 8/10 | 1/10 | Stronger for Dill |
| Indigestion | 8/10 | 1/10 | Stronger for Dill |
| Infection (general) | 8/10 | 2/10 | Stronger for Dill |
| Inflammation (general) | 8/10 | 2/10 | Stronger for Dill |
| Skin irritation | 8/10 | 1/10 | Stronger for Dill |
| Wounds | 8/10 | 1/10 | Stronger for Dill |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Seed essential oil dominated by the monoterpene ketone carvone and limonene, giving dill its characteristic aroma and much of its carminative and antimicrobial activity.
Antioxidant flavonoids and phenolics identified in metabolomic analysis of leaf and seed extracts.
The volatile oil, dominated by terpinen-4-ol and cis-sabinene hydrate in true sweet marjoram, gives most of the antimicrobial and antioxidant activity.
Contribute to antioxidant and anti-inflammatory activity.
Pharmacological Actions
Anethum graveolens (dill) extract and essential oil induce ROS-mediated apoptosis in melanoma and lung adenocarcinoma cells (preclinical).
Traditional & Indicated Uses
inferred from anti-inflammatory action
Anethum graveolens (dill) extract induces ROS-mediated apoptosis in HT-144 melanoma cells, and its essential oil is selectively cytotoxic and pro-apoptotic against A549 lung adenocarcinoma cells (preclinical).
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
inferred from anti-inflammatory action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from sedative action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
Widely used as a food herb/spice; WHO monograph notes a “generally regarded as safe” status as a flavouring agent (World Health Organization, 2007). Allergic reactions (including oral itching, swelling, urticaria, vomiting/diarrhoea) are reported; avoid if you react to Apiaceae-family plants (World Health Organization, 2007; Egyptian Drug Authority, n.d.).
Duke (2002) provides clinical evidence (score 2) for dill's antibacterial and antispasmodic activities, consistent with Commission E and PhEur approvals. Traditional uses include management of colic, dyspepsia, and flatulence. The plant is a well-documented lactagogue (promotes milk production) and has a mild hypotensive effect. Dose: 1–3 g seeds as tea three times daily. Dill is generally safe (++) with no known significant contraindications at culinary and medicinal doses (Duke, 2002).
Generally very safe as a culinary herb. Essential oil should not be ingested in large amounts and avoided in pregnancy. Theoretically may interact with anticoagulants. Avoid medicinal doses during pregnancy.
Duke (2002) rates marjoram (Origanum majorana) as +++ and notes antiviral, antispasmodic, COX-2 inhibitory, and antiseptic activities at the experimental level (score 1). It demonstrates antiherpetic activity in vitro. The plant contains rosmarinic acid and thymol, which contribute to antioxidant and antimicrobial effects. Dose: 1–2 g dried herb as tea three times daily or equivalent preparations. Duke notes the plant is generally well-tolerated with no significant contraindications at usual herbal doses (Duke, 2002).
External Ids
Botanical Description
Aromatic annual herb with a slender, hollow, ridged, blue-green stem. The leaves are finely divided into thread-like segments, feathery and soft, similar to fennel but more delicate. Small yellow flowers are borne in flat, wide compound umbels at the stem tips in summer, ripening into flattened, ridged, aromatic seeds (fruits).[1]
Tender perennial subshrub (Lamiaceae), often grown as an annual in cold climates, 20-60 cm tall, with square, downy, much-branched stems. Leaves are opposite, small, grey-green and ovate. Tiny white to pale pink, two-lipped flowers are borne in distinctive knot-like clustered spikes, the origin of the common name 'knotted marjoram'.[6]
Habitat
Believed native to the eastern Mediterranean, Western Asia and southern Russia; widely cultivated as a culinary and medicinal herb in gardens and fields across Europe, Asia and the Americas.[1]
Native to Cyprus, Turkey and the eastern Mediterranean, and widely cultivated as a culinary and medicinal herb in gardens worldwide; prefers full sun and well-drained, often calcareous soils.[6]
Harvesting
Leaves are picked fresh through the growing season; the seeds are harvested in late summer once the umbels have browned and dried, then threshed and dried further before storage.
The aerial flowering parts are cut just before or at flowering (summer), when essential-oil content is highest, and dried quickly in a warm, shaded, well-ventilated place.[9]
Traditional Uses
Dill seed and leaf have a long culinary-medicinal history as a carminative digestive remedy for colic, dyspepsia and flatulence, and as a traditional lactagogue (galactagogue) to support breastfeeding; dill water ('gripe water') is a classic infant remedy for colic.[1]
Marjoram has a long Mediterranean culinary-medicinal tradition as a digestive carminative and mild sedative for indigestion, cramping and poor sleep, and as an antiseptic for minor wounds and infections. Modern research confirms antispasmodic, antimicrobial, antioxidant and anti-inflammatory activity from its essential oil and phenolic constituents.[6, 8]
Preparations
Dosage
The WHO monograph on Fructus Anethi gives an average daily dose of 3 g of the dried ripe fruit, or 0.1-0.3 g of the essential oil, or the equivalent in other preparations. Educational reference only, not a prescription.
References
Lookalikes Review
Dangerous Lookalikes
Not documented
Drug Class Interactions
Not documented
References & Sources
- Thanuma, J., Phetcharaburanin, J., Dokduang, H., Loilome, W. and others (2025) 'Metabolomic analysis of bioactive compounds in dill (Anethum graveolens L.) extracts', PeerJ, 13, pp. e19567. doi:10.7717/peerj.19567 Preclinical
https://doi.org/10.7717/peerj.19567 - Sharma, H., Yang, H., Sharma, N. and An, S.S.A (2024) 'Neuroprotection by Anethum graveolens (Dill) Seeds and Its Phytocompounds in SH-SY5Y Neuroblastoma Cell Lines and Acellular Assays', International Journal of Molecular Sciences, 25(13), pp. 7104. doi:10.3390/ijms25137104 Preclinical
https://doi.org/10.3390/ijms25137104 - Mohammed, F.A., Elkady, A.I., Syed, F.Q., Mirza, M.B. and others (2018) 'Anethum graveolens (dill) - A medicinal herb induces apoptosis and cell cycle arrest in HepG2 cell line', Journal of Ethnopharmacology, 219, pp. 15-22. doi:10.1016/j.jep.2018.03.008 Preclinical
https://doi.org/10.1016/j.jep.2018.03.008 - Haidari, F., Zakerkish, M., Borazjani, F., Ahmadi Angali, K. and others (2020) 'The effects of Anethum graveolens (dill) powder supplementation on clinical and metabolic status in patients with type 2 diabetes', Trials, 21(1), pp. 483. doi:10.1186/s13063-020-04401-3 Randomized trial
https://doi.org/10.1186/s13063-020-04401-3 - Li, Z., Xue, Y., Li, M., Guo, Q. and others (2018) 'The Antioxidation of Different Fractions of Dill (Anethum graveolens) and Their Influences on Cytokines in Macrophages RAW264.7', Journal of Oleo Science, 67(12), pp. 1535-1541. doi:10.5650/jos.ess18134 Preclinical
https://doi.org/10.5650/jos.ess18134 - Jang, S.A., Lee, S.J., Hwang, Y.H. and Ha, H (2023) 'Anti-Osteoporotic Potential of Water Extract of Anethum graveolens L. Seeds', Nutrients, 15(19), pp. 4302. doi:10.3390/nu15194302 Preclinical
https://doi.org/10.3390/nu15194302 - Stavri, M. and Gibbons, S (2005) 'The antimycobacterial constituents of dill (Anethum graveolens)', Phytotherapy Research, 19(11), pp. 938-941. doi:10.1002/ptr.1758 Preclinical
https://doi.org/10.1002/ptr.1758 - Orhan, I.E., Senol, F.S., Ozturk, N., Celik, S.A. and others (2013) 'Phytochemical contents and enzyme inhibitory and antioxidant properties of Anethum graveolens L. (dill) samples cultivated under organic and conventional agricultural conditions', Food and Chemical Toxicology, 59, pp. 96-103. doi:10.1016/j.fct.2013.05.053 Preclinical
https://doi.org/10.1016/j.fct.2013.05.053 - Tian, J., Ban, X., Zeng, H., He, J. and others (2012) 'The mechanism of antifungal action of essential oil from dill (Anethum graveolens L.) on Aspergillus flavus', PLoS One, 7(1), pp. e30147. doi:10.1371/journal.pone.0030147 Preclinical
https://doi.org/10.1371/journal.pone.0030147 - Castro, L.M., Pinto, N.B., Moura, M.Q., Villela, M.M. and others (2021) 'Antihelminthic action of the Anethum graveolens essential oil on Haemonchus contortus eggs and larvae', Brazilian Journal of Biology, 81(1), pp. 183-188. doi:10.1590/1519-6984.225856 Preclinical
https://doi.org/10.1590/1519-6984.225856 - World Health Organization (2007) 'Fructus Anethi'. Available at: https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 Traditional / reference
https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 - Egyptian Drug Authority (n.d.). Available at: https://dev.edaegypt.gov.eg/media/a4kf0fmp/anethum-graveolens_1.pdf Traditional / reference
https://dev.edaegypt.gov.eg/media/a4kf0fmp/anethum-graveolens_1.pdf - Haidari, F., Mohammadshahi, M., Zarei, M., Gorji, Z., Asghari-Jafarabadi, M. and Alizadeh, M (2020) 'The effects of anethum graveolens (dill) powder supplementation on clinical and metabolic status in patients with type 2 diabetes'. doi:10.1016/j.ctim.2020.102367 Randomized trial
https://doi.org/10.1016/j.ctim.2020.102367 - Mousavi, S.M., Pizarro, A.B., Akhgarjand, C., Bagheri, A., Persad, E., Karimi, E., Wong, A. and Jayedi, A (2022) 'The effects of Anethum graveolens (dill) supplementation on lipid profile and glycemic control: a systematic review and meta-analysis of randomized controlled trials', 62(21), pp. 5705--5716. doi:10.1080/10408398.2021.1889459 Meta-analysis / review
https://doi.org/10.1080/10408398.2021.1889459 - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:837530-1 Traditional / reference
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:837530-1 - World Health Organization (2007) 'WHO monographs on selected medicinal plants, Volume 3: ‘Fructus Anethi'. Available at: https://e-lactancia.org/media/papers/Fitoterapia-Plantas-WHO-03_2007.pdf Traditional / reference
https://e-lactancia.org/media/papers/Fitoterapia-Plantas-WHO-03_2007.pdf - Aydogmus-Ozturk, F. and Jahan, H. and Ozturk, M. and Gunaydin, K. and Choudhary, M.I (2020) 'Preclinical study of the medicinal plants for the treatment of malignant melanoma', Molecular Biology Reports, 47(8), pp. 5975-5983. doi:10.1007/s11033-020-05671-5 Preclinical
https://doi.org/10.1007/s11033-020-05671-5 - Tavakkol Afshari, H.S. and Homayouni Tabrizi, M. and Ardalan, T. and Jalili Anoushirvani, N. and Mahdizadeh, R (2021) 'Anethum graveolens Essential Oil Nanoemulsions (AGEO-NE) as an Exclusive Apoptotic Inducer in Human Lung Adenocarcinoma (A549) Cells', Nutrition and Cancer, 74(4), pp. 1411-1419. doi:10.1080/01635581.2021.1952450 Preclinical
https://doi.org/10.1080/01635581.2021.1952450 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Washington State University Extension, Yakima County (2025) 'One Invasive, One Native, Both Deadly'. Available at: https://extension.wsu.edu/yakima/2025/08/09/one-invasive-one-native-both-deadly/ Traditional / reference
https://extension.wsu.edu/yakima/2025/08/09/one-invasive-one-native-both-deadly/ - King County Noxious Weeds (2024) 'Poison hemlock (Conium maculatum) identification and control'. Available at: https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock Traditional / reference
https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock - Dayan, A.D (2024) 'Death of Socrates: a likely case of poison hemlock (Conium maculatum) poisoning', Clinical Toxicology (Philadelphia, Pa.), 62(1), pp. 56-60. doi:10.1080/15563650.2024.2309328 Clinical study
https://doi.org/10.1080/15563650.2024.2309328 - Grow Forage Cook Ferment 'Poison Hemlock: How to Identify and Potential Look-alikes'. Available at: https://www.growforagecookferment.com/poison-hemlock/ Traditional / reference
https://www.growforagecookferment.com/poison-hemlock/
- Rehman, N.U., Ansari, M.N., Ahmad, W. and Ali, A (2024) 'Calcium Channel Inhibitory Effect of Marjoram (Origanum majorana L.): Its Medicinal Use in Diarrhea and Gut Hyperactivity', Frontiers in Bioscience (Landmark Edition), 29(2), pp. 47. doi:10.31083/j.fbl2902047 Preclinical
https://doi.org/10.31083/j.fbl2902047 - Hussein, Z. and Yasir, S.M (2022) 'Origanum majorana attenuates ciprofloxacin-induced nephropathy in rats', Wiadomosci Lekarskie, 75(12), pp. 3046-3049. doi:10.36740/WLek202212126 Preclinical
https://doi.org/10.36740/WLek202212126 - Elfiky, A.M., Ibrahim, R.S., Khattab, A.R., Kadry, M.O. and others (2025) 'Exploring the therapeutic potential of marjoram (Origanum majorana L.) in polycystic ovary syndrome: insights from serum metabolomics, network pharmacology and experimental validation', BMC Complementary Medicine and Therapies, 25(1), pp. 67. doi:10.1186/s12906-025-04774-5 Preclinical
https://doi.org/10.1186/s12906-025-04774-5 - Waller, S.B., Cleff, M.B., de Mattos, C.B., da Silva, C.C. and others (2021) 'Protection of the marjoram (Origanum majorana Linn.) essential oil in cutaneous sporotrichosis caused by Sporothrix brasiliensis', Natural Product Research, 35(17), pp. 2977-2981. doi:10.1080/14786419.2019.1678617 Preclinical
https://doi.org/10.1080/14786419.2019.1678617 - Haj-Husein, I., Tukan, S. and Alkazaleh, F (2016) 'The effect of marjoram (Origanum majorana) tea on the hormonal profile of women with polycystic ovary syndrome: a randomised controlled pilot study', Journal of Human Nutrition and Dietetics, 29(1), pp. 105-111. doi:10.1111/jhn.12290 Randomized trial
https://doi.org/10.1111/jhn.12290 - Bouyahya, A., Chamkhi, I., Benali, T., Guaouguaou, F.E. and others (2021) 'Traditional use, phytochemistry, toxicology, and pharmacology of Origanum majorana L', Journal of Ethnopharmacology, 265, pp. 113318. doi:10.1016/j.jep.2020.113318 Meta-analysis / review
https://doi.org/10.1016/j.jep.2020.113318 - Al-Howiriny, T., Alsheikh, A., Alqasoumi, S., Al-Yahya, M. and others (2009) 'Protective Effect of Origanum majorana L. 'Marjoram' on various models of gastric mucosal injury in rats', The American Journal of Chinese Medicine, 37(3), pp. 531-545. doi:10.1142/S0192415X0900703X Preclinical
https://doi.org/10.1142/S0192415X0900703X - Bina, F. and Rahimi, R (2017) 'Sweet Marjoram: A Review of Ethnopharmacology, Phytochemistry, and Biological Activities', Journal of Evidence-Based Complementary & Alternative Medicine, 22(1), pp. 175-185. doi:10.1177/2156587216650793 Meta-analysis / review
https://doi.org/10.1177/2156587216650793 - Paudel, P.N., Satyal, P., Satyal, R., Setzer, W.N. and others (2022) 'Chemical Composition, Enantiomeric Distribution, Antimicrobial and Antioxidant Activities of Origanum majorana L. Essential Oil from Nepal', Molecules, 27(18), pp. 6136. doi:10.3390/molecules27186136 Preclinical
https://doi.org/10.3390/molecules27186136 - Makrane, H., Aziz, M., Mekhfi, H., Ziyyat, A. and others (2019) 'Origanum majorana L. extract exhibit positive cooperative effects on the main mechanisms involved in acute infectious diarrhea', Journal of Ethnopharmacology, 239, pp. 111503. doi:10.1016/j.jep.2018.09.005 Preclinical
https://doi.org/10.1016/j.jep.2018.09.005 - Baser, K.H.C (2008) 'Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils', 14(29), pp. 3106--3119. doi:10.2174/138161208786404227 Traditional / reference
https://doi.org/10.2174/138161208786404227 - Hoffmann, D (2003) 'Medical Herbalism'. Traditional / reference
https://scholar.google.com/scholar?q=Medical%20Herbalism - Seidler-Lozykowska, K. et al (2016) 'Essential oil content and composition of sweet marjoram (Origanum majorana L.) grown in Poland', 62(1), pp. 37--45. Traditional / reference
https://scholar.google.com/scholar?q=Essential%20oil%20content%20and%20composition%20of%20sweet%20marjoram%20%28Origanum%20majorana%20L.%29%20grown%20in%20Poland - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.