Plant Comparison
Dill vs Chili Pepper
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Dill and Chili Pepper: they share 8 indicated uses (arthritis / joint pain, bloating, cardiovascular / heart health, …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Dill | Chili Pepper | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 8/10 | 6/10 | Stronger for Dill |
| Bloating | 8/10 | 1/10 | Stronger for Dill |
| Cardiovascular / heart health | 8/10 | 3/10 | Stronger for Dill |
| Indigestion | 8/10 | 1/10 | Stronger for Dill |
| Infection (general) | 8/10 | 1/10 | Stronger for Dill |
| Inflammation (general) | 8/10 | 1/10 | Stronger for Dill |
| Skin irritation | 8/10 | 1/10 | Stronger for Dill |
| Wounds | 8/10 | 1/10 | Stronger for Dill |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Seed essential oil dominated by the monoterpene ketone carvone and limonene, giving dill its characteristic aroma and much of its carminative and antimicrobial activity.
Antioxidant flavonoids and phenolics identified in metabolomic analysis of leaf and seed extracts.
The pungent alkaloid-like compounds responsible for the fruit's heat and its counterirritant/analgesic action via TRPV1 receptor desensitisation.
Give ripe red fruit its colour and contribute antioxidant and anti-inflammatory activity.
Antioxidant and anti-inflammatory flavonoids identified in leaf and fruit extracts.
Pharmacological Actions
Anethum graveolens (dill) extract and essential oil induce ROS-mediated apoptosis in melanoma and lung adenocarcinoma cells (preclinical).
Traditional & Indicated Uses
inferred from anti-inflammatory action
Anethum graveolens (dill) extract induces ROS-mediated apoptosis in HT-144 melanoma cells, and its essential oil is selectively cytotoxic and pro-apoptotic against A549 lung adenocarcinoma cells (preclinical).
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
inferred from anti-inflammatory action
inferred from analgesic action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
Widely used as a food herb/spice; WHO monograph notes a “generally regarded as safe” status as a flavouring agent (World Health Organization, 2007). Allergic reactions (including oral itching, swelling, urticaria, vomiting/diarrhoea) are reported; avoid if you react to Apiaceae-family plants (World Health Organization, 2007; Egyptian Drug Authority, n.d.).
Duke (2002) provides clinical evidence (score 2) for dill's antibacterial and antispasmodic activities, consistent with Commission E and PhEur approvals. Traditional uses include management of colic, dyspepsia, and flatulence. The plant is a well-documented lactagogue (promotes milk production) and has a mild hypotensive effect. Dose: 1–3 g seeds as tea three times daily. Dill is generally safe (++) with no known significant contraindications at culinary and medicinal doses (Duke, 2002).
Capsaicin causes intense burning sensation; avoid contact with eyes and mucous membranes. High oral doses can cause gastrointestinal irritation, nausea, and diarrhoea. Topical preparations may cause skin irritation and should be used diluted. Not recommended for individuals with active peptic ulcers. Caution with anticoagulants — capsaicin may enhance bleeding risk. During pregnancy, culinary amounts are considered safe, but high-dose supplements should be avoided. Repeated topical application leads to desensitisation (TRPV1 depletion), which is the basis for its analgesic use. Children under 2 should not be given capsaicin-containing topical products (Basu and Bhattacharyya, 2023).
Duke (2002) rates cayenne/chili pepper (Capsicum annuum) highly for its clinically documented analgesic, counterirritant, and rubefacient activities. Commission E approves topical capsaicin preparations for muscle pain, arthritis, and neuralgia (score 2). The active compound capsaicin depletes substance P in sensory neurons upon repeated application, reducing pain signals. Capsaicin cream (0.025–0.075%) is a validated treatment for post-herpetic neuralgia, diabetic neuropathy, and osteoarthritis pain. Internal use can irritate mucous membranes; external use requires avoiding contact with eyes and mucous membranes (Duke, 2002).
External Ids
Botanical Description
Aromatic annual herb with a slender, hollow, ridged, blue-green stem. The leaves are finely divided into thread-like segments, feathery and soft, similar to fennel but more delicate. Small yellow flowers are borne in flat, wide compound umbels at the stem tips in summer, ripening into flattened, ridged, aromatic seeds (fruits).[1]
Bushy annual or short-lived perennial herb (grown as an annual in temperate climates) with glossy, oval to lance-shaped leaves. Small, star-shaped, white to greenish flowers give way to the characteristic fleshy, hollow fruit (a berry), which ripens from green through yellow to red and varies enormously in size, shape and pungency between cultivars.[1]
Habitat
Believed native to the eastern Mediterranean, Western Asia and southern Russia; widely cultivated as a culinary and medicinal herb in gardens and fields across Europe, Asia and the Americas.[1]
Native to Central and South America; cultivated worldwide in warm and temperate climates as a food and medicinal crop, thriving in full sun on well-drained soil.[1]
Harvesting
Leaves are picked fresh through the growing season; the seeds are harvested in late summer once the umbels have browned and dried, then threshed and dried further before storage.
Fruit is picked at the desired stage of ripeness (green for milder use, fully red for maximum capsaicin and carotenoid content) through summer and autumn; seeds are separated and dried from fully ripe fruit.
Traditional Uses
Dill seed and leaf have a long culinary-medicinal history as a carminative digestive remedy for colic, dyspepsia and flatulence, and as a traditional lactagogue (galactagogue) to support breastfeeding; dill water ('gripe water') is a classic infant remedy for colic.[1]
Chili pepper fruit has a long history across the Americas and, after global spread, in many other traditional medicine systems as a warming digestive stimulant and topical counterirritant/analgesic for muscle and joint pain, building on capsaicin's now well-documented ability to desensitise pain-sensing nerve fibres with repeated application.[1]
Preparations
Standardised capsaicin cream or patch applied to the affected area for muscle, joint or nerve pain; repeated application depletes substance P and reduces pain signalling.
Dosage
The WHO monograph on Fructus Anethi gives an average daily dose of 3 g of the dried ripe fruit, or 0.1-0.3 g of the essential oil, or the equivalent in other preparations. Educational reference only, not a prescription.
The EU herbal monograph on Capsici fructus gives semi-solid dosage forms corresponding to 40-53 mg capsaicinoids per 100 g, applied as a thin layer to the affected area 2-4 times daily, in adults and elderly. For medicated plasters, a maximum of 1 plaster per day applied for at least 4 and up to 12 hours, with at least 12 hours before a new plaster is applied to the same area. Not recommended under 18 years. Expect an initial burning sensation that lessens with repeated use. Note the monograph covers hot chilli fruit (C. annuum var. minimum and small-fruited C. frutescens), not sweet peppers. Educational reference only, not a prescription.
References
Lookalikes Review
Dangerous Lookalikes
Not documented
References & Sources
- Thanuma, J., Phetcharaburanin, J., Dokduang, H., Loilome, W. and others (2025) 'Metabolomic analysis of bioactive compounds in dill (Anethum graveolens L.) extracts', PeerJ, 13, pp. e19567. doi:10.7717/peerj.19567 Preclinical
https://doi.org/10.7717/peerj.19567 - Sharma, H., Yang, H., Sharma, N. and An, S.S.A (2024) 'Neuroprotection by Anethum graveolens (Dill) Seeds and Its Phytocompounds in SH-SY5Y Neuroblastoma Cell Lines and Acellular Assays', International Journal of Molecular Sciences, 25(13), pp. 7104. doi:10.3390/ijms25137104 Preclinical
https://doi.org/10.3390/ijms25137104 - Mohammed, F.A., Elkady, A.I., Syed, F.Q., Mirza, M.B. and others (2018) 'Anethum graveolens (dill) - A medicinal herb induces apoptosis and cell cycle arrest in HepG2 cell line', Journal of Ethnopharmacology, 219, pp. 15-22. doi:10.1016/j.jep.2018.03.008 Preclinical
https://doi.org/10.1016/j.jep.2018.03.008 - Haidari, F., Zakerkish, M., Borazjani, F., Ahmadi Angali, K. and others (2020) 'The effects of Anethum graveolens (dill) powder supplementation on clinical and metabolic status in patients with type 2 diabetes', Trials, 21(1), pp. 483. doi:10.1186/s13063-020-04401-3 Randomized trial
https://doi.org/10.1186/s13063-020-04401-3 - Li, Z., Xue, Y., Li, M., Guo, Q. and others (2018) 'The Antioxidation of Different Fractions of Dill (Anethum graveolens) and Their Influences on Cytokines in Macrophages RAW264.7', Journal of Oleo Science, 67(12), pp. 1535-1541. doi:10.5650/jos.ess18134 Preclinical
https://doi.org/10.5650/jos.ess18134 - Jang, S.A., Lee, S.J., Hwang, Y.H. and Ha, H (2023) 'Anti-Osteoporotic Potential of Water Extract of Anethum graveolens L. Seeds', Nutrients, 15(19), pp. 4302. doi:10.3390/nu15194302 Preclinical
https://doi.org/10.3390/nu15194302 - Stavri, M. and Gibbons, S (2005) 'The antimycobacterial constituents of dill (Anethum graveolens)', Phytotherapy Research, 19(11), pp. 938-941. doi:10.1002/ptr.1758 Preclinical
https://doi.org/10.1002/ptr.1758 - Orhan, I.E., Senol, F.S., Ozturk, N., Celik, S.A. and others (2013) 'Phytochemical contents and enzyme inhibitory and antioxidant properties of Anethum graveolens L. (dill) samples cultivated under organic and conventional agricultural conditions', Food and Chemical Toxicology, 59, pp. 96-103. doi:10.1016/j.fct.2013.05.053 Preclinical
https://doi.org/10.1016/j.fct.2013.05.053 - Tian, J., Ban, X., Zeng, H., He, J. and others (2012) 'The mechanism of antifungal action of essential oil from dill (Anethum graveolens L.) on Aspergillus flavus', PLoS One, 7(1), pp. e30147. doi:10.1371/journal.pone.0030147 Preclinical
https://doi.org/10.1371/journal.pone.0030147 - Castro, L.M., Pinto, N.B., Moura, M.Q., Villela, M.M. and others (2021) 'Antihelminthic action of the Anethum graveolens essential oil on Haemonchus contortus eggs and larvae', Brazilian Journal of Biology, 81(1), pp. 183-188. doi:10.1590/1519-6984.225856 Preclinical
https://doi.org/10.1590/1519-6984.225856 - World Health Organization (2007) 'Fructus Anethi'. Available at: https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 Traditional / reference
https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 - Egyptian Drug Authority (n.d.). Available at: https://dev.edaegypt.gov.eg/media/a4kf0fmp/anethum-graveolens_1.pdf Traditional / reference
https://dev.edaegypt.gov.eg/media/a4kf0fmp/anethum-graveolens_1.pdf - Haidari, F., Mohammadshahi, M., Zarei, M., Gorji, Z., Asghari-Jafarabadi, M. and Alizadeh, M (2020) 'The effects of anethum graveolens (dill) powder supplementation on clinical and metabolic status in patients with type 2 diabetes'. doi:10.1016/j.ctim.2020.102367 Randomized trial
https://doi.org/10.1016/j.ctim.2020.102367 - Mousavi, S.M., Pizarro, A.B., Akhgarjand, C., Bagheri, A., Persad, E., Karimi, E., Wong, A. and Jayedi, A (2022) 'The effects of Anethum graveolens (dill) supplementation on lipid profile and glycemic control: a systematic review and meta-analysis of randomized controlled trials', 62(21), pp. 5705--5716. doi:10.1080/10408398.2021.1889459 Meta-analysis / review
https://doi.org/10.1080/10408398.2021.1889459 - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:837530-1 Traditional / reference
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:837530-1 - World Health Organization (2007) 'WHO monographs on selected medicinal plants, Volume 3: ‘Fructus Anethi'. Available at: https://e-lactancia.org/media/papers/Fitoterapia-Plantas-WHO-03_2007.pdf Traditional / reference
https://e-lactancia.org/media/papers/Fitoterapia-Plantas-WHO-03_2007.pdf - Aydogmus-Ozturk, F. and Jahan, H. and Ozturk, M. and Gunaydin, K. and Choudhary, M.I (2020) 'Preclinical study of the medicinal plants for the treatment of malignant melanoma', Molecular Biology Reports, 47(8), pp. 5975-5983. doi:10.1007/s11033-020-05671-5 Preclinical
https://doi.org/10.1007/s11033-020-05671-5 - Tavakkol Afshari, H.S. and Homayouni Tabrizi, M. and Ardalan, T. and Jalili Anoushirvani, N. and Mahdizadeh, R (2021) 'Anethum graveolens Essential Oil Nanoemulsions (AGEO-NE) as an Exclusive Apoptotic Inducer in Human Lung Adenocarcinoma (A549) Cells', Nutrition and Cancer, 74(4), pp. 1411-1419. doi:10.1080/01635581.2021.1952450 Preclinical
https://doi.org/10.1080/01635581.2021.1952450 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Washington State University Extension, Yakima County (2025) 'One Invasive, One Native, Both Deadly'. Available at: https://extension.wsu.edu/yakima/2025/08/09/one-invasive-one-native-both-deadly/ Traditional / reference
https://extension.wsu.edu/yakima/2025/08/09/one-invasive-one-native-both-deadly/ - King County Noxious Weeds (2024) 'Poison hemlock (Conium maculatum) identification and control'. Available at: https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock Traditional / reference
https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock - Dayan, A.D (2024) 'Death of Socrates: a likely case of poison hemlock (Conium maculatum) poisoning', Clinical Toxicology (Philadelphia, Pa.), 62(1), pp. 56-60. doi:10.1080/15563650.2024.2309328 Clinical study
https://doi.org/10.1080/15563650.2024.2309328 - Grow Forage Cook Ferment 'Poison Hemlock: How to Identify and Potential Look-alikes'. Available at: https://www.growforagecookferment.com/poison-hemlock/ Traditional / reference
https://www.growforagecookferment.com/poison-hemlock/
- Cho, S.Y., Kim, H.W., Lee, M.K., Kim, H.J., Kim, J.B., Choe, J.S., Lee, Y.M. and Jang, H.H (2020) 'Antioxidant and anti-inflammatory activities in relation to the flavonoids composition of pepper (Capsicum annuum L.)', Antioxidants, 9(10), pp. 986. doi:10.3390/antiox9100986 Preclinical
https://doi.org/10.3390/antiox9100986 - Khan, F.A., Mahmood, T., Ali, M., Saeed, A. and Maalik, A (2014) 'Pharmacological importance of an ethnobotanical plant: Capsicum annuum L', Natural Product Research, 28(16), pp. 1267-1274. doi:10.1080/14786419.2014.895723 Meta-analysis / review
https://doi.org/10.1080/14786419.2014.895723 - Srinivasan, K (2016) 'Biological activities of red pepper (Capsicum annuum) and its pungent principle capsaicin: a review', Critical Reviews in Food Science and Nutrition, 56(9), pp. 1488-1500. doi:10.1080/10408398.2013.772090 Meta-analysis / review
https://doi.org/10.1080/10408398.2013.772090 - Hernandez-Perez, T., Gomez-Garcia, M.D.R., Valverde, M.E. and Paredes-Lopez, O (2020) 'Capsicum annuum (hot pepper): an ancient Latin-American crop with outstanding bioactive compounds and nutraceutical potential. A review', Comprehensive Reviews in Food Science and Food Safety, 19(6), pp. 2972-2993. doi:10.1111/1541-4337.12634 Meta-analysis / review
https://doi.org/10.1111/1541-4337.12634 - Sanati, S., Razavi, B.M. and Hosseinzadeh, H (2018) 'A review of the effects of Capsicum annuum L. and its constituent, capsaicin, in metabolic syndrome', Iranian Journal of Basic Medical Sciences, 21(5), pp. 439-448. doi:10.22038/IJBMS.2018.25200.6238 Meta-analysis / review
https://doi.org/10.22038/IJBMS.2018.25200.6238 - Mandal, S.K., Rath, S.K., Logesh, R., Mishra, S.K., Devkota, H.P. and Das, N (2023) 'Capsicum annuum L. and its bioactive constituents: a critical review of a traditional culinary spice in terms of its modern pharmacological potentials with toxicological issues', Phytotherapy Research, 37(3), pp. 965-1002. doi:10.1002/ptr.7660 Meta-analysis / review
https://doi.org/10.1002/ptr.7660 - Grojja, Y., Hajlaoui, H., Luca, S.V., Abidi, J., Skalicka-Wozniak, K., Zouari, S. and Bouaziz, M (2023) 'Untargeted phytochemical profiling, antioxidant, and antimicrobial activities of a Tunisian Capsicum annuum cultivar', Molecules, 28(17), pp. 6346. doi:10.3390/molecules28176346 Preclinical
https://doi.org/10.3390/molecules28176346 - Hernandez-Ortega, M., Ortiz-Moreno, A., Hernandez-Navarro, M.D., Chamorro-Cevallos, G., Dorantes-Alvarez, L. and Necoechea-Mondragon, H (2012) 'Antioxidant, antinociceptive, and anti-inflammatory effects of carotenoids extracted from dried pepper (Capsicum annuum L.)', Journal of Biomedicine and Biotechnology, 2012, pp. 524019. doi:10.1155/2012/524019 Preclinical
https://doi.org/10.1155/2012/524019 - Maji, A.K. and Banerji, P (2016) 'Phytochemistry and gastrointestinal benefits of the medicinal spice, Capsicum annuum L. (Chilli): a review', Journal of Complementary & Integrative Medicine, 13(2), pp. 97-122. doi:10.1515/jcim-2015-0037 Meta-analysis / review
https://doi.org/10.1515/jcim-2015-0037 - Marrelli, M., Menichini, F. and Conforti, F (2016) 'Hypolipidemic and antioxidant properties of hot pepper flower (Capsicum annuum L.)', Plant Foods for Human Nutrition, 71(3), pp. 301-306. doi:10.1007/s11130-016-0560-7 Preclinical
https://doi.org/10.1007/s11130-016-0560-7 - Song, C., Yu, C., Zhu, X., Luo, X., Zhang, Y., Meng, L., Luo, Y., Chang, H., Qin, C. and Liu, Y (2020) 'A new capsaicin-containing phenolic glycoside from Capsicum annuum L', Natural Product Research, 36(2), pp. 546-552. doi:10.1080/14786419.2020.1789983 Preclinical
https://doi.org/10.1080/14786419.2020.1789983 - European Medicines Agency (HMPC) (2015) 'European Union herbal monograph on Capsicum annuum L. var. minimum (Miller) Heiser and small fruited varieties of Capsicum frutescens L., fructus'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-capsicum-annuum-l-var-minimum-miller-heiser-and-small-fruited-varieties-capsicum-frutescens-l-fructus_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-capsicum-annuum-l-var-minimum-miller-heiser-and-small-fruited-varieties-capsicum-frutescens-l-fructus_en.pdf - Anand, P. and Bley, K (2011) 'Topical capsaicin for pain management: therapeutic potential and mechanisms of action of the new high-concentration capsaicin 8% patch', 107(4), pp. 490--502. doi:10.1093/bja/aer260 Clinical study
https://doi.org/10.1093/bja/aer260 - Basu, S. and Bhattacharyya, S (2023) 'Capsicum and capsaicin: a comprehensive review of chemistry, pharmacology, and therapeutic applications', 22(5), pp. 1413--1442. doi:10.1007/s11101-023-09875-8 Traditional / reference
https://doi.org/10.1007/s11101-023-09875-8 - Derry, S., Rice, A.S., Cole, P., Tan, T. and Moore, R.A (2017) 'Topical capsaicin (high concentration) for chronic neuropathic pain in adults'. doi:10.1002/http://14651858.CD007393.pub4 Randomized trial
https://doi.org/10.1002/http://14651858.CD007393.pub4 - Royal Botanic Gardens, Kew (n.d.) 'Capsicum annuum L'. Available at: https://powo.science.kew.org/taxon/urn:lsid:http://ipni.org:names:841033-1 Traditional / reference
https://powo.science.kew.org/taxon/urn:lsid:http://ipni.org:names:841033-1 - Molina-Torres, J., García-Chávez, A. and Ramírez-Chávez, E (1999) 'Antimicrobial properties of alkamides present in flavouring plants traditionally used in Mesoamerica', 64(3), pp. 241--248. doi:10.1016/S0378-8741(98)00131-4 Traditional / reference
https://doi.org/10.1016/S0378-8741(98)00131-4 - Lv, J., Qi, L., Yu, C. et al (2015) 'Consumption of spicy foods and total and cause specific mortality: population based cohort study'. doi:10.1136/bmj.h3942 Clinical study
https://doi.org/10.1136/bmj.h3942 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.