Plant Comparison

Aloe Vera vs Chili Pepper

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant AAloe VeraAloe veraAsphodelaceaeFull monograph →
Plant BChili PepperCapsicum annuumSolanaceaeFull monograph →

At a glance

Aloe Vera and Chili Pepper: they share 8 indicated uses (arthritis / joint pain, back pain, headache, …); 3 pharmacological actions in common.

Aloe VeraChili Pepper
Constituents33
Pharmacological actions64
Indicated uses1111
Safety notes22
Cited sources3219
Indicated uses
Only Aloe Vera
BruisingCancer (anticancer research)Eczema
Shared (8)
Arthritis / joint painBack painHeadacheInfection (general)Inflammation (general)Pain (general)Skin irritationWounds
Only Chili Pepper
BloatingCardiovascular / heart healthIndigestion
Pharmacological actions
Only Aloe Vera
Anticancer (preclinical)Emollient / skin-soothingVulnerary (wound healing)
Shared (3)
Analgesic (pain relief)Anti-inflammatoryAntimicrobial
Only Chili Pepper
Digestive aid

Evidence face-off — shared uses

ConditionAloe VeraChili PepperVerdict
Arthritis / joint pain1/106/10Stronger for Chili Pepper
Back pain1/106/10Stronger for Chili Pepper
Headache1/101/10Comparable evidence
Infection (general)1/101/10Comparable evidence
Inflammation (general)1/101/10Comparable evidence
Pain (general)1/106/10Stronger for Chili Pepper
Skin irritation1/101/10Comparable evidence
Wounds1/101/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Polysaccharides (acemannan)[1, 13]

Acemannan and other glucomannans are the principal gel polysaccharides, underlying the emollient and wound-healing effects.

PolysaccharidesMucilage
Anthraquinones (aloin, aloe-emodin)[1]

Found mainly in the leaf latex (not the inner gel); responsible for the traditional laxative effect and requiring caution with prolonged use.

Anthraquinones
Enzymes, vitamins and minerals[1]

Minor bioactive enzymes, vitamins (including C and E) and minerals contribute to the antioxidant and skin-conditioning properties of the gel.

Capsaicinoids (capsaicin, dihydrocapsaicin)[8]

The pungent alkaloid-like compounds responsible for the fruit's heat and its counterirritant/analgesic action via TRPV1 receptor desensitisation.

Carotenoids (capsanthin, beta-carotene)[8]

Give ripe red fruit its colour and contribute antioxidant and anti-inflammatory activity.

Carotenoids
Flavonoids (luteolin, apigenin)[1]

Antioxidant and anti-inflammatory flavonoids identified in leaf and fruit extracts.

FlavonoidsLuteolinApigenin

Pharmacological Actions

Analgesic (pain relief)[13, 14, 15, 16, 17, 18, 19, 20]
Anti-inflammatory[1, 2, 7, 10, 11, 13, 14, 15, 16, 17, 18, 19, 20]
Anticancer (preclinical)[21, 22, 23, 24, 25, 26]

Aloe vera and its anthraquinone aloe-emodin show dose-dependent antiproliferative and pro-apoptotic activity against multiple cancer types in vitro and in vivo (preclinical).

Antimicrobial[1, 3, 9, 11, 13, 14, 15, 16, 17, 18, 19, 20]
Emollient / skin-soothing[4, 13, 14, 15, 16, 17, 18, 19, 20]
Vulnerary (wound healing)[4, 5, 8, 10, 13, 14, 15, 16, 17, 18, 19, 20]
Analgesic (pain relief)[3, 6, 8, 13, 14, 15, 16]
Anti-inflammatory[1, 2, 5, 8, 13, 14, 15, 16]
Antimicrobial[7, 14, 16, 17]
Digestive aid[3, 4, 9, 14, 16]

Traditional & Indicated Uses

Arthritis / joint pain[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Back pain[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Back pain
Bruising[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Cancer (anticancer research)[21, 22, 23, 24, 25, 26]Traditional · 2/10

Aloe-emodin, an Aloe vera anthraquinone, induces apoptosis and inhibits growth of gastric, oral squamous, hepatocellular, lung (incl. xenograft) and glioblastoma cancer cells, modulating caspases, Bcl-2/Bax, PI3K/Akt and MEK/ERK signalling (preclinical).

Evidence: 2
Label: Cancer (anticancer research)
Eczema[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from emollient action

Evidence: 1
Label: Eczema
Headache[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Headache
Infection (general)[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Pain (general)[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10
Evidence: 1
Label: Pain (general)
Skin irritation[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[13, 14, 15, 16, 17, 18, 19, 20]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Arthritis / joint pain[13, 14, 15, 16, 17]Moderate · 6/10

inferred from anti-inflammatory action

Evidence: 6
Label: Arthritis / joint pain
Back pain[13, 14, 15, 16, 17]Moderate · 6/10

inferred from analgesic action

Evidence: 6
Label: Back pain
Bloating[14, 16, 17]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Cardiovascular / heart health[14, 16, 17, 18]Limited · 3/10
Evidence: 3
Label: Cardiovascular / heart health
Headache[14, 16, 17]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Headache
Indigestion[14, 16, 17]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Indigestion
Infection (general)[14, 16, 17]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[14, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Pain (general)[13, 14, 15, 16, 17]Moderate · 6/10
Evidence: 6
Label: Pain (general)
Skin irritation[14, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[14, 16, 17]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds

Safety, Cautions & Contraindications

Safety note[13, 14, 15, 16, 17, 18, 19, 20]Caution

Topical use of aloe gel is generally safe for most people. Oral use of aloe latex as a laxative is potentially unsafe with prolonged use due to risk of dehydration, electrolyte imbalance, and potential kidney damage. Aloe latex contains anthraquinone glycosides which may cause abdominal cramping and diarrhea. Not recommended during pregnancy or breastfeeding. May interact with diabetes medications, diuretics, and laxatives. Oral aloe gel at typical doses appears safe short-term but long-term safety is unclear. Allergic reactions possible in sensitive individuals.

Safety note[13, 14, 15, 16, 17, 18, 19, 20, 27]Caution

Duke (2002) reports clinical evidence (score 2/3) supporting aloe gel's use in psoriasis, constipation (in adults), and as a vulnerary. Gel preparations have been clinically validated for peptic ulcers (excluding stress-induced), radiation burns, and skin ulcers. Dose: 1 tablespoon gel three times daily or 50–200 mg dried juice equivalent per day as a laxative. An important safety distinction is made: the gel (inner leaf mucilage) is AHPA Class 1 (safe), while the inner leaf juice or dried latex is Class 2b due to anthraquinone content and is contraindicated in intestinal inflammation, colitis, Crohn's disease, appendicitis, and during menstruation (Duke, 2002).

Safety note[13, 14, 15, 16, 17, 18]Caution

Capsaicin causes intense burning sensation; avoid contact with eyes and mucous membranes. High oral doses can cause gastrointestinal irritation, nausea, and diarrhoea. Topical preparations may cause skin irritation and should be used diluted. Not recommended for individuals with active peptic ulcers. Caution with anticoagulants — capsaicin may enhance bleeding risk. During pregnancy, culinary amounts are considered safe, but high-dose supplements should be avoided. Repeated topical application leads to desensitisation (TRPV1 depletion), which is the basis for its analgesic use. Children under 2 should not be given capsaicin-containing topical products (Basu and Bhattacharyya, 2023).

Safety note[13, 14, 15, 16, 17, 18, 19]Caution

Duke (2002) rates cayenne/chili pepper (Capsicum annuum) highly for its clinically documented analgesic, counterirritant, and rubefacient activities. Commission E approves topical capsaicin preparations for muscle pain, arthritis, and neuralgia (score 2). The active compound capsaicin depletes substance P in sensory neurons upon repeated application, reducing pain signals. Capsaicin cream (0.025–0.075%) is a validated treatment for post-herpetic neuralgia, diabetic neuropathy, and osteoarthritis pain. Internal use can irritate mucous membranes; external use requires avoiding contact with eyes and mucous membranes (Duke, 2002).

External Ids

Gbif: 2777724
Powo: urn:lsid:ipni.org:names:530017-1
Wikidata: Q80079
Gbif: 2932944
Wikidata: Q1380

Botanical Description

Succulent, rosette-forming perennial with thick, fleshy, lance-shaped leaves edged with soft, pale teeth, each leaf filled with a clear, slippery, mucilaginous gel beneath a tougher green rind. In favourable conditions it produces a tall flowering spike bearing tubular yellow (sometimes orange) flowers.[1]

Height: Leaves 40-80 cm; flower spike to about 1 m
Habit: Succulent, rosette-forming perennial
Leaves: Thick, fleshy, lance-shaped, edged with soft pale teeth, filled with clear mucilaginous gel
Flowers: Tubular yellow (occasionally orange) flowers on a tall, unbranched or sparsely branched spike
Stem: Very short, often inconspicuous, below the leaf rosette
Root: Shallow, fibrous roots
Fruit: Capsule (rarely produced in cultivation)
Flowering Period: Varies with climate; typically under warm, dry conditions

Bushy annual or short-lived perennial herb (grown as an annual in temperate climates) with glossy, oval to lance-shaped leaves. Small, star-shaped, white to greenish flowers give way to the characteristic fleshy, hollow fruit (a berry), which ripens from green through yellow to red and varies enormously in size, shape and pungency between cultivars.[1]

Height: 0.5-1.5 m
Habit: Bushy annual or short-lived perennial herb
Leaves: Glossy, oval to lance-shaped
Flowers: Small, star-shaped, white to greenish, borne singly or in small clusters
Stem: Branching, semi-woody at the base in older plants
Root: Fibrous root system
Fruit: Fleshy, hollow berry, ripening green to yellow/orange/red, containing numerous flat seeds
Flowering Period: Summer, continuing until frost

Habitat

Believed native to the Arabian Peninsula, and now cultivated and naturalised throughout arid and semi-arid tropical and subtropical regions worldwide as a garden, medicinal and commercial crop.[1]

Native to Central and South America; cultivated worldwide in warm and temperate climates as a food and medicinal crop, thriving in full sun on well-drained soil.[1]

Harvesting

Outer, mature leaves are cut close to the base as needed; the clear inner gel (mucilage) is separated from the outer rind and from the bitter yellow latex (aloin-containing exudate) just under the rind, since the gel and the latex have different uses and safety profiles.[1]

Parts: Leaf
Season: Year-round where climate permits, from mature outer leaves

Fruit is picked at the desired stage of ripeness (green for milder use, fully red for maximum capsaicin and carotenoid content) through summer and autumn; seeds are separated and dried from fully ripe fruit.

Parts: Fruit, Seed
Season: Summer to autumn, at desired ripeness

Traditional Uses

Aloe vera has an ancient reputation, recorded from ancient Egypt onward, as a topical remedy for burns, wounds and skin inflammation (the 'burn plant' / 'first aid plant'), and the bitter leaf latex has been used traditionally as a stimulant laxative. It remains one of the most widely used topical botanicals for skin care and minor wound healing.[1]

Chili pepper fruit has a long history across the Americas and, after global spread, in many other traditional medicine systems as a warming digestive stimulant and topical counterirritant/analgesic for muscle and joint pain, building on capsaicin's now well-documented ability to desensitise pain-sensing nerve fibres with repeated application.[1]

Preparations

Fresh gel[1]

Clear inner leaf gel applied fresh, or as a stabilised commercial gel, directly to the skin for burns, minor wounds and skin irritation.

Oral juice/gel[1]

Inner leaf gel (latex-free) taken orally, used traditionally for digestive support.

Topical cream/ointment (capsaicin)[8]

Standardised capsaicin cream or patch applied to the affected area for muscle, joint or nerve pain; repeated application depletes substance P and reduces pain signalling.

Dosage

Topical gel[12]

The WHO monograph on Aloe Vera Gel specifies fresh gel, or preparations containing 10-70% fresh gel, applied to the affected skin area. Educational reference only, not a prescription.

Topical capsaicin cream[12]

The EU herbal monograph on Capsici fructus gives semi-solid dosage forms corresponding to 40-53 mg capsaicinoids per 100 g, applied as a thin layer to the affected area 2-4 times daily, in adults and elderly. For medicated plasters, a maximum of 1 plaster per day applied for at least 4 and up to 12 hours, with at least 12 hours before a new plaster is applied to the same area. Not recommended under 18 years. Expect an initial burning sensation that lessens with repeated use. Note the monograph covers hot chilli fruit (C. annuum var. minimum and small-fruited C. frutescens), not sweet peppers. Educational reference only, not a prescription.

References

REF-2234, REF-2235, REF-2236, REF-2237, REF-2238, REF-2239, REF-2240, REF-2241, REF-2242, REF-2243, REF-2244
REF-2142, REF-2143, REF-2144, REF-2145, REF-2146, REF-2147, REF-2148, REF-2149, REF-2150, REF-2151, REF-2152

Drug Class Interactions

Safety note[28, 29]Caution
Drug Class: antidiabetics
Mechanism: Aloe vera (taken internally) can lower blood sugar - a meta-analysis found improved fasting glucose in prediabetes and improved HbA1c in type 2 diabetes - so combining it with diabetes medicines may increase the risk of hypoglycaemia; monitor blood glucose.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Not documented

Lookalikes Review

Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Dangerous Lookalikes

Safety note[30, 31, 32]Irritant
Dangerous Plant: agave-americana
Confused Part: Fleshy leaves harvested for their soothing gel; agave forms a very similar large rosette of thick, pointed succulent leaves.
Confusion Context: Aloe vera is grown and harvested for the clear soothing gel inside its fleshy leaves. Agave (Agave americana and relatives) forms a very similar rosette of thick, pointed succulent leaves and, as Gardening Know How notes, the two are easily confused if you have not grown both. But agave is not soothing: its sap contains calcium oxalate raphides, steroidal saponins and acrid oils, and peer-reviewed dermatology reports document painful irritant contact dermatitis (even purpura) from agave sap. Applying or ingesting agave sap in mistake for aloe gel can burn the skin, mouth and gut. Because both are common houseplants and garden succulents, this is a realistic mix-up.
Distinguishing Features: Inside the leaf (decisive): snap or cut a leaf. Aloe leaves are soft and filled with clear, slippery gel. Agave leaves are tough and fibrous/stringy with no gel - you cannot easily snap them by hand., Leaf tip and edge: agave leaves end in one hard, sharp terminal spine and often have stiff sharp teeth; aloe has softer, more pliable leaves with soft whitish teeth and no rigid terminal spike., Whole plant over time: aloe flowers repeatedly on a branched stalk and lives on; agave typically flowers only once, on a huge tall stalk, then dies.
Key Test: Cut a leaf. Clear, slippery gel inside a soft leaf = aloe (safe gel). A tough, fibrous leaf with no gel, ending in a hard sharp spine = agave - its sap is an irritant that can burn skin, mouth and gut, so do not use it. When in doubt, do not apply or consume it unless you are certain it is aloe.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Not documented

References & Sources

  1. Sanchez, M., Gonzalez-Burgos, E., Iglesias, I. and Gomez-Serranillos, M.P (2020) 'Pharmacological update properties of Aloe vera and its major active constituents', Molecules, 25(6), pp. 1324. doi:10.3390/molecules25061324 Meta-analysis / review
    https://doi.org/10.3390/molecules25061324
  2. Kaur, S. and Bains, K (2023) 'Aloe barbadensis Miller (Aloe vera)', International Journal for Vitamin and Nutrition Research, 94(3-4), pp. 308-321. doi:10.1024/0300-9831/a000797 Meta-analysis / review
    https://doi.org/10.1024/0300-9831/a000797
  3. Catalano, A., Ceramella, J., Iacopetta, D., Marra, M., Conforti, F., Lupi, F.R., Gabriele, D., Borges, F. and Sinicropi, M.S (2024) 'Aloe vera - an extensive review focused on recent studies', Foods, 13(13), pp. 2155. doi:10.3390/foods13132155 Meta-analysis / review
    https://doi.org/10.3390/foods13132155
  4. Surjushe, A., Vasani, R. and Saple, D.G (2008) 'Aloe vera: a short review', Indian Journal of Dermatology, 53(4), pp. 163-166. doi:10.4103/0019-5154.44785 Meta-analysis / review
    https://doi.org/10.4103/0019-5154.44785
  5. Liang, J., Cui, L., Li, J., Guan, S., Zhang, K. and Li, J (2020) 'Aloe vera: a medicinal plant used in skin wound healing', Tissue Engineering Part B: Reviews, 27(5), pp. 455-474. doi:10.1089/ten.TEB.2020.0236 Meta-analysis / review
    https://doi.org/10.1089/ten.TEB.2020.0236
  6. Guo, X. and Mei, N (2016) 'Aloe vera: a review of toxicity and adverse clinical effects', Journal of Environmental Science and Health Part C, 34(2), pp. 77-96. doi:10.1080/10590501.2016.1166826 Meta-analysis / review
    https://doi.org/10.1080/10590501.2016.1166826
  7. Boyapati, R., Peeta, J., Dhulipalla, R., Kolaparthy, L., Adurty, C. and Cheruvu, R.N.S (2024) 'Comparative evaluation of the efficacy of probiotic, Aloe vera, povidine-iodine, and chlorhexidine mouthwashes in the treatment of gingival inflammation: a randomized controlled trial', Dental and Medical Problems, 61(2), pp. 181-190. doi:10.17219/dmp/156425 Randomized trial
    https://doi.org/10.17219/dmp/156425
  8. Hekmatpou, D., Mehrabi, F., Rahzani, K. and Aminiyan, A (2019) 'The effect of Aloe vera clinical trials on prevention and healing of skin wound: a systematic review', Iranian Journal of Medical Sciences, 44(1), pp. 1-9. Meta-analysis / review
    https://scholar.google.com/scholar?q=The%20effect%20of%20Aloe%20vera%20clinical%20trials%20on%20prevention%20and%20healing%20of%20skin%20wound%3A%20a%20systematic%20review
  9. Gao, Y., Kuok, K.I., Jin, Y. and Wang, R (2018) 'Biomedical applications of Aloe vera', Critical Reviews in Food Science and Nutrition, 59(sup1), pp. S244-S256. doi:10.1080/10408398.2018.1496320 Meta-analysis / review
    https://doi.org/10.1080/10408398.2018.1496320
  10. Feily, A. and Namazi, M.R (2009) 'Aloe vera in dermatology: a brief review', Giornale Italiano di Dermatologia e Venereologia, 144(1), pp. 85-91. Meta-analysis / review
    https://scholar.google.com/scholar?q=Aloe%20vera%20in%20dermatology%3A%20a%20brief%20review
  11. Sierra-Garcia, G.D., Castro-Rios, R., Gonzalez-Horta, A., Lara-Arias, J. and Chavez-Montes, A (2014) 'Acemannan, an extracted polysaccharide from Aloe vera: a literature review', Natural Product Communications, 9(8), pp. 1217-1221. doi:10.1177/1934578x1400900836 Meta-analysis / review
    https://doi.org/10.1177/1934578x1400900836
  12. World Health Organization (1999) 'Aloe Vera Gel'. Available at: https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 Traditional / reference
    https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37
  13. Femenia A, Sánchez ES, Simal S, Rosselló C. Compositional features of polysaccharides from Aloe vera (1999) ';39(2):109-117', 39(2). Traditional / reference
    https://scholar.google.com/scholar?q=%3B39%282%29%3A109-117.
  14. Catalano A, Iacopetta D, Ceramella J, et al. Aloe vera - An extensive review focused on recent studies. Foods. 2024;13 (2024) ';13(13):2155', 13(13). Traditional / reference
    https://scholar.google.com/scholar?q=%3B13%2813%29%3A2155.
  15. Hekmatpou D, Mehrabi F, Rahzani K, Aminiyan A. The effect of Aloe vera clinical trials on prevention and healing of skin wound: A systematic review. Iran J Med Sci. 2019;44 (2019) ';44(1):1-9', 44(1). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6330525/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC6330525/
  16. National Center for Complementary and Integrative Health. Aloe vera. NIH. 2020. https://www.nccih.nih.gov/health/aloe-vera (2020) 'https://www.nccih.nih.gov/health/aloe-vera'. Available at: https://www.nccih.nih.gov/health/aloe-vera Traditional / reference
    https://www.nccih.nih.gov/health/aloe-vera
  17. Sahu PK, Giri DD, Singh R, et al. Therapeutic and medicinal uses of Aloe vera: A review. Pharmacol Pharm. 2013;4:599-610 (2013) ';4:599-610'. Traditional / reference
    https://scholar.google.com/scholar?q=%3B4%3A599-610.
  18. Sánchez M, González-Burgos E, Iglesias I, Gómez-Serranillos MP. Pharmacological update properties of Aloe vera and its major active constituents. Molecules. 2020;25 (2020) ';25(6):1324', 25(6). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC7144722/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC7144722/
  19. Surjushe A, Vasani R, Saple DG. Aloe vera: A short review. Indian J Dermatol. 2008;53 (2008) ';53(4):163-166', 53(4). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC2763764/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC2763764/
  20. Ulbricht C, Armstrong J, Basch E, et al. An evidence-based systematic review of Aloe vera by the Natural Standard Research Collaboration. J Herb Pharmacother. 2008;7 (2008) ';7(3-4):279-323'. Available at: https://www.ncbi.nlm.nih.gov/books/NBK92765/ Traditional / reference
    https://www.ncbi.nlm.nih.gov/books/NBK92765/
  21. Haroon, N. and Amjad, A. and Maaz, M. and Noman, A.M. and Anees, N. and Muhammad, Z. and Shah, M. and Al Abdulmonem, W (2026) 'Phytochemistry, Bioavailability, and Molecular Mechanisms Underlying Multitarget Anticancer Activity of Aloe vera', Nutrients, 18(12), pp. 2034. doi:10.3390/nu18122034 Preclinical
    https://doi.org/10.3390/nu18122034
  22. Chen, S.-H. and Lin, K.-Y. and Chang, C.-C. and Fang, C.-L. and Lin, C.-P (2007) 'Aloe-emodin-induced apoptosis in human gastric carcinoma cells', Food and Chemical Toxicology, 45(11), pp. 2296-2303. doi:10.1016/j.fct.2007.06.005 Preclinical
    https://doi.org/10.1016/j.fct.2007.06.005
  23. Li, Q. and Wen, J. and Yu, K. and Shu, Y. and He, W. and Chu, H. and Zhang, B. and Ge, C (2018) 'Aloe-emodin induces apoptosis in human oral squamous cell carcinoma SCC15 cells', BMC Complementary and Alternative Medicine, 18(1), pp. 296. doi:10.1186/s12906-018-2353-z Preclinical
    https://doi.org/10.1186/s12906-018-2353-z
  24. Arcella, A. and Sanchez, M (2021) 'Natural substances to potentiate canonical glioblastoma chemotherapy', Journal of Chemotherapy, 33(5), pp. 276-287. doi:10.1080/1120009X.2021.1873633 Preclinical
    https://doi.org/10.1080/1120009X.2021.1873633
  25. Zhu, M. and He, Q. and Wang, Y. and Duan, L. and Rong, K. and Wu, Y. and Ding, Y. and Mi, Y. and Ge, X. and Yang, X. and Yu, Y (2023) 'Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments', Frontiers in Pharmacology, 14, pp. 1238841. doi:10.3389/fphar.2023.1238841 Preclinical
    https://doi.org/10.3389/fphar.2023.1238841
  26. Kim, H.J. and Choi, J.W. and Ree, J. and Lim, J.S. and Lee, J. and Kim, J.I. and Thapa, S.B. and Sohng, J.K. and Park, Y.I (2022) 'Aloe emodin 3-O-glucoside inhibits cell growth and migration and induces apoptosis of non-small-cell lung cancer cells via suppressing MEK/ERK and Akt signalling pathways', Life Sciences, 300, pp. 120495. doi:10.1016/j.lfs.2022.120495 Preclinical
    https://doi.org/10.1016/j.lfs.2022.120495
  27. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  28. Suksomboon, N., Poolsup, N. and Punthanitisarn, S (2016) 'Effect of Aloe vera on glycaemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis', Journal of Clinical Pharmacy and Therapeutics, 41(2), pp. 180-188. doi:10.1111/jcpt.12382 Meta-analysis / review
    https://doi.org/10.1111/jcpt.12382
  29. Suksomboon, N., Poolsup, N. and Punthanitisarn, S (2016) 'Effect of Aloe vera on glycaemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis', Journal of Clinical Pharmacy and Therapeutics, 41(2), pp. 180-188. doi:10.1111/jcpt.12382 Meta-analysis / review
    https://doi.org/10.1111/jcpt.12382
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.