Plant Comparison
Agrimony vs Dill
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Agrimony and Dill: they share 7 indicated uses (arthritis / joint pain, bloating, cancer (anticancer research), …); 4 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Agrimony | Dill | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 2/10 | 8/10 | Stronger for Dill |
| Bloating | 2/10 | 8/10 | Stronger for Dill |
| Cancer (anticancer research) | 2/10 | 2/10 | Comparable evidence |
| Indigestion | 2/10 | 8/10 | Stronger for Dill |
| Inflammation (general) | 2/10 | 8/10 | Stronger for Dill |
| Skin irritation | 1/10 | 8/10 | Stronger for Dill |
| Wounds | 2/10 | 8/10 | Stronger for Dill |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Responsible for the characteristic astringency.
Antioxidant and anti-inflammatory constituents.
Seed essential oil dominated by the monoterpene ketone carvone and limonene, giving dill its characteristic aroma and much of its carminative and antimicrobial activity.
Antioxidant flavonoids and phenolics identified in metabolomic analysis of leaf and seed extracts.
Pharmacological Actions
Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat)
Agrimonia eupatoria ethanolic extract is cytotoxic to breast, colon, lung and cervical cancer cells and inhibits the PI3K/Akt/mTOR pathway (preclinical/in silico).
Anethum graveolens (dill) extract and essential oil induce ROS-mediated apoptosis in melanoma and lung adenocarcinoma cells (preclinical).
Traditional & Indicated Uses
inferred from bitter-tonic action
inferred from anti-inflammatory action
Agrimonia eupatoria ethanolic extract shows dose-dependent cytotoxicity against MCF-7 (breast), HT-29 (colon), A549 (lung) and HeLa (cervical) cancer cells and inhibits the PI3K/Akt/mTOR/COX-2/MMP-2 axis (preclinical).
Astringent (relief of mild diarrhoea)
Mild bitter digestive tonic (indigestion)
Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat); Vulnerary (minor skin inflammation and small superficial wounds, topical)
inferred from astringent action
Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat)
inferred from anti-inflammatory action
Anethum graveolens (dill) extract induces ROS-mediated apoptosis in HT-144 melanoma cells, and its essential oil is selectively cytotoxic and pro-apoptotic against A549 lung adenocarcinoma cells (preclinical).
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
Safety, Cautions & Contraindications
Traditional-use indication only: if diarrhoea persists longer than 3-4 days, or symptoms of mouth/throat inflammation persist beyond about a week, a doctor should be consulted.
Use during pregnancy and breastfeeding is not recommended, as safety has not been established.
Widely used as a food herb/spice; WHO monograph notes a “generally regarded as safe” status as a flavouring agent (World Health Organization, 2007). Allergic reactions (including oral itching, swelling, urticaria, vomiting/diarrhoea) are reported; avoid if you react to Apiaceae-family plants (World Health Organization, 2007; Egyptian Drug Authority, n.d.).
Duke (2002) provides clinical evidence (score 2) for dill's antibacterial and antispasmodic activities, consistent with Commission E and PhEur approvals. Traditional uses include management of colic, dyspepsia, and flatulence. The plant is a well-documented lactagogue (promotes milk production) and has a mild hypotensive effect. Dose: 1–3 g seeds as tea three times daily. Dill is generally safe (++) with no known significant contraindications at culinary and medicinal doses (Duke, 2002).
External Ids
Botanical Description
Slender, downy perennial herb with a basal rosette of pinnately compound leaves and a single, unbranched, upright flowering stem. The leaflets are toothed, alternating large and small, and silvery-downy beneath. Small, five-petalled, bright yellow flowers are borne closely along a slender terminal spike (raceme), opening a few at a time from the base upwards, giving the old name 'church steeples'. After flowering, small bristly, hooked burrs form that cling to clothing and animal fur for dispersal.[13, 14]
Aromatic annual herb with a slender, hollow, ridged, blue-green stem. The leaves are finely divided into thread-like segments, feathery and soft, similar to fennel but more delicate. Small yellow flowers are borne in flat, wide compound umbels at the stem tips in summer, ripening into flattened, ridged, aromatic seeds (fruits).[1]
Habitat
Believed native to the eastern Mediterranean, Western Asia and southern Russia; widely cultivated as a culinary and medicinal herb in gardens and fields across Europe, Asia and the Americas.[1]
Harvesting
The flowering aerial parts are cut in summer, at the start of flowering, and dried promptly in a warm, airy, shaded place.[13]
Leaves are picked fresh through the growing season; the seeds are harvested in late summer once the umbels have browned and dried, then threshed and dried further before storage.
Traditional Uses
Agrimony has a long folk history as an astringent remedy for mild diarrhoea, as a gargle for sore throats and mild mouth/throat inflammation, and as a mild bitter digestive tonic; it has also been applied topically to minor wounds and skin inflammation. It is officially recognised in the European Union herbal monograph for traditional use in mild diarrhoea and mild inflammation of the mouth or throat.[13, 14]
Dill seed and leaf have a long culinary-medicinal history as a carminative digestive remedy for colic, dyspepsia and flatulence, and as a traditional lactagogue (galactagogue) to support breastfeeding; dill water ('gripe water') is a classic infant remedy for colic.[1]
Preparations
Dosage
The EU herbal monograph gives 1.5-4 g of the comminuted herb in 250 mL (or less) of boiling water as an infusion, 2-3 times daily, in adolescents, adults and elderly. As a gargle for mild oral or throat inflammation, 1.5 g in 150 mL of boiling water 2-4 times daily, or a decoction of 3-4.5 g in 250 mL 2-3 times daily. Educational reference only, not a prescription.
The EU herbal monograph gives 1-4 mL three times daily (orally, or as a gargle for oral and throat use). Educational reference only, not a prescription.
The WHO monograph on Fructus Anethi gives an average daily dose of 3 g of the dried ripe fruit, or 0.1-0.3 g of the essential oil, or the equivalent in other preparations. Educational reference only, not a prescription.
References
Lookalikes Review
Dangerous Lookalikes
Not documented
References & Sources
- Malheiros, J., Simoes, D.M., Figueirinha, A., Cotrim, M.D. and Fonseca, D.A (2022) 'Agrimonia eupatoria L.: An integrative perspective on ethnomedicinal use, phenolic composition and pharmacological activity', Journal of Ethnopharmacology, pp. 2022. doi:10.1016/j.jep.2022.115498 Preclinical
https://doi.org/10.1016/j.jep.2022.115498 - Paluch, Z., Biriczova, L., Pallag, G., Carvalheiro Marques, E., Vargova, N. and Kmonickova, E (2020) 'The therapeutic effects of Agrimonia eupatoria L', Physiological Research, pp. S555--S571. doi:10.33549/physiolres.934641 Preclinical
https://doi.org/10.33549/physiolres.934641 - Kuczmannova, A., Balazova, A., Racanska, E., Kamenikova, M., Fialova, S., Majernik, J., Nagy, M., Gal, P. and Mucaji, P (2016) 'Agrimonia eupatoria L. and Cynara cardunculus L. water infusions: comparison of anti-diabetic activities', Molecules, 21(5), pp. 564. doi:10.3390/molecules21050564 Preclinical
https://doi.org/10.3390/molecules21050564 - Huzio, N., Grytsyk, A., Raal, A., Grytsyk, L. and Koshovyi, O (2022) 'Phytochemical and pharmacological research in Agrimonia eupatoria L. herb extract with anti-inflammatory and hepatoprotective properties', Plants, 11(18), pp. 2371. doi:10.3390/plants11182371 Preclinical
https://doi.org/10.3390/plants11182371 - Correia, H.S., Batista, M.T. and Dinis, T.C.P (2007) 'The activity of an extract and fraction of Agrimonia eupatoria L. against reactive species', BioFactors, 29(2-3), pp. 91-104. doi:10.1002/biof.552029209 Preclinical
https://doi.org/10.1002/biof.552029209 - Granica, S., Kluge, H., Horn, G., Matkowski, A. and Kiss, A.K (2015) 'The phytochemical investigation of Agrimonia eupatoria L. and Agrimonia procera Wallr. as valid sources of Agrimoniae herba - the pharmacopoeial plant material', Journal of Pharmaceutical and Biomedical Analysis, 114, pp. 272-279. doi:10.1016/j.jpba.2015.05.027 Preclinical
https://doi.org/10.1016/j.jpba.2015.05.027 - Tsirigotis-Maniecka, M., Zaczynska, E., Czarny, A., Jadczyk, P., Uminska-Wasiluk, B., Gancarz, R. and Pawlaczyk-Graja, I (2023) 'Antioxidant and protective effects of the polyphenolic glycoconjugate from Agrimonia eupatoria L. herb in the prevention of inflammation in human cells', Journal of Functional Biomaterials, 14(4), pp. 182. doi:10.3390/jfb14040182 Preclinical
https://doi.org/10.3390/jfb14040182 - Kwon, D.H., Kwon, H.Y., Kim, H.J., Chang, E.J., Kim, M.B., Yoon, S.K., Song, E.Y., Yoon, D.Y., Lee, Y.H., Choi, I.S. and Choi, Y.K (2005) 'Inhibition of hepatitis B virus by an aqueous extract of Agrimonia eupatoria L', Phytotherapy Research, 19(4), pp. 355-358. doi:10.1002/ptr.1689 Preclinical
https://doi.org/10.1002/ptr.1689 - Karlinska, E., Romanowska, B. and Kosmala, M (2021) 'The aerial parts of Agrimonia procera Wallr. and Agrimonia eupatoria L. as a source of polyphenols, and especially agrimoniin and flavonoids', Molecules, 26(24), pp. 7706. doi:10.3390/molecules26247706 Preclinical
https://doi.org/10.3390/molecules26247706 - Kuczmannova, A., Gal, P., Varinska, L., Treml, J., Kovac, I., Novotny, M., Vasilenko, T., Dall'Acqua, S., Nagy, M. and Mucaji, P (2015) 'Agrimonia eupatoria L. and Cynara cardunculus L. water infusions: phenolic profile and comparison of antioxidant activities', Molecules, 20(11), pp. 20538-20550. doi:10.3390/molecules201119715 Preclinical
https://doi.org/10.3390/molecules201119715 - Ivanova, D., Vankova, D. and Nashar, M (2013) 'Agrimonia eupatoria tea consumption in relation to markers of inflammation, oxidative status and lipid metabolism in healthy subjects', Archives of Physiology and Biochemistry, 119(1), pp. 32-37. doi:10.3109/13813455.2012.729844 Clinical study
https://doi.org/10.3109/13813455.2012.729844 - Venskutonis, P.R., Skemaite, M. and Ragazinskiene, O (2007) 'Radical scavenging capacity of Agrimonia eupatoria and Agrimonia procera', Fitoterapia, 78(2), pp. 166-168. doi:10.1016/j.fitote.2006.10.002 Preclinical
https://doi.org/10.1016/j.fitote.2006.10.002 - European Medicines Agency (HMPC) (2015) 'European Union herbal monograph on Agrimonia eupatoria L., herba (Agrimoniae herba)'. Available at: https://www.ema.europa.eu/en/medicines/herbal/agrimoniae-herba Traditional / reference
https://www.ema.europa.eu/en/medicines/herbal/agrimoniae-herba - (2022) 'Agrimonia eupatoria L.: An integrative perspective on ethnomedicinal use, phenolic composition and pharmacological activity', Journal of Ethnopharmacology. doi:10.1016/j.jep.2022.115498 Traditional / reference
https://doi.org/10.1016/j.jep.2022.115498 - Herbal Reality (n.d.) 'Agrimony (Agrimonia eupatoria): Benefits, Uses, Safety'. Available at: https://www.herbalreality.com/herb/agrimony/ Traditional / reference
https://www.herbalreality.com/herb/agrimony/ - Lee, K.H. and Rhee, K.H (2016) 'Anti-nociceptive effect of Agrimonia eupatoria extract on a cisplatin-induced neuropathic model', African Journal of Traditional, Complementary and Alternative Medicines, 13(5), pp. 139--144. doi:10.21010/ajtcam.v13i5.18 Preclinical
https://doi.org/10.21010/ajtcam.v13i5.18 - Ginovyan, M. and Gevorgyan, S. and Javrushyan, H. and Kusznierewicz, B. and Koss-Mikolajczyk, I. and Sahakyan, N. and Bartoszek, A. and Avtandilyan, N (2026) 'Inhibition of the PI3K signaling pathway in cancer cells by Agrimonia eupatoria L. ethanolic extract: identification of tricoumaroyl spermidine as a potential PI3K inhibitor', BMC Complementary Medicine and Therapies, 26(1), pp. 41. doi:10.1186/s12906-025-05231-z Preclinical
https://doi.org/10.1186/s12906-025-05231-z - Shareef, S.H., Asaad, N.K., Gheni, N.A., Fisal, D.N., Shakir Agha, N.F., Ali, R.T. and Abdulla, M.A (2025) 'Agrimonia eupatoria leaf extract attenuates alcohol-induced oxidative stress, ulcer and alleviates stomach damage in rats', Food Science and Nutrition, 13(11). doi:10.1002/fsn3.71203 Preclinical
https://doi.org/10.1002/fsn3.71203 - Vasilenko, T., Kovac, I., Slezak, M., Durkac, J., Perzelova, V., Coma, M. and others (2022) 'Agrimonia eupatoria L. aqueous extract improves skin wound healing: an in vitro study in fibroblasts and keratinocytes and in vivo study in rats', In Vivo, 36(3), pp. 1236--1244. doi:10.21873/invivo.12822 Preclinical
https://doi.org/10.21873/invivo.12822
- Thanuma, J., Phetcharaburanin, J., Dokduang, H., Loilome, W. and others (2025) 'Metabolomic analysis of bioactive compounds in dill (Anethum graveolens L.) extracts', PeerJ, 13, pp. e19567. doi:10.7717/peerj.19567 Preclinical
https://doi.org/10.7717/peerj.19567 - Sharma, H., Yang, H., Sharma, N. and An, S.S.A (2024) 'Neuroprotection by Anethum graveolens (Dill) Seeds and Its Phytocompounds in SH-SY5Y Neuroblastoma Cell Lines and Acellular Assays', International Journal of Molecular Sciences, 25(13), pp. 7104. doi:10.3390/ijms25137104 Preclinical
https://doi.org/10.3390/ijms25137104 - Mohammed, F.A., Elkady, A.I., Syed, F.Q., Mirza, M.B. and others (2018) 'Anethum graveolens (dill) - A medicinal herb induces apoptosis and cell cycle arrest in HepG2 cell line', Journal of Ethnopharmacology, 219, pp. 15-22. doi:10.1016/j.jep.2018.03.008 Preclinical
https://doi.org/10.1016/j.jep.2018.03.008 - Haidari, F., Zakerkish, M., Borazjani, F., Ahmadi Angali, K. and others (2020) 'The effects of Anethum graveolens (dill) powder supplementation on clinical and metabolic status in patients with type 2 diabetes', Trials, 21(1), pp. 483. doi:10.1186/s13063-020-04401-3 Randomized trial
https://doi.org/10.1186/s13063-020-04401-3 - Li, Z., Xue, Y., Li, M., Guo, Q. and others (2018) 'The Antioxidation of Different Fractions of Dill (Anethum graveolens) and Their Influences on Cytokines in Macrophages RAW264.7', Journal of Oleo Science, 67(12), pp. 1535-1541. doi:10.5650/jos.ess18134 Preclinical
https://doi.org/10.5650/jos.ess18134 - Jang, S.A., Lee, S.J., Hwang, Y.H. and Ha, H (2023) 'Anti-Osteoporotic Potential of Water Extract of Anethum graveolens L. Seeds', Nutrients, 15(19), pp. 4302. doi:10.3390/nu15194302 Preclinical
https://doi.org/10.3390/nu15194302 - Stavri, M. and Gibbons, S (2005) 'The antimycobacterial constituents of dill (Anethum graveolens)', Phytotherapy Research, 19(11), pp. 938-941. doi:10.1002/ptr.1758 Preclinical
https://doi.org/10.1002/ptr.1758 - Orhan, I.E., Senol, F.S., Ozturk, N., Celik, S.A. and others (2013) 'Phytochemical contents and enzyme inhibitory and antioxidant properties of Anethum graveolens L. (dill) samples cultivated under organic and conventional agricultural conditions', Food and Chemical Toxicology, 59, pp. 96-103. doi:10.1016/j.fct.2013.05.053 Preclinical
https://doi.org/10.1016/j.fct.2013.05.053 - Tian, J., Ban, X., Zeng, H., He, J. and others (2012) 'The mechanism of antifungal action of essential oil from dill (Anethum graveolens L.) on Aspergillus flavus', PLoS One, 7(1), pp. e30147. doi:10.1371/journal.pone.0030147 Preclinical
https://doi.org/10.1371/journal.pone.0030147 - Castro, L.M., Pinto, N.B., Moura, M.Q., Villela, M.M. and others (2021) 'Antihelminthic action of the Anethum graveolens essential oil on Haemonchus contortus eggs and larvae', Brazilian Journal of Biology, 81(1), pp. 183-188. doi:10.1590/1519-6984.225856 Preclinical
https://doi.org/10.1590/1519-6984.225856 - World Health Organization (2007) 'Fructus Anethi'. Available at: https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 Traditional / reference
https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 - Egyptian Drug Authority (n.d.). Available at: https://dev.edaegypt.gov.eg/media/a4kf0fmp/anethum-graveolens_1.pdf Traditional / reference
https://dev.edaegypt.gov.eg/media/a4kf0fmp/anethum-graveolens_1.pdf - Haidari, F., Mohammadshahi, M., Zarei, M., Gorji, Z., Asghari-Jafarabadi, M. and Alizadeh, M (2020) 'The effects of anethum graveolens (dill) powder supplementation on clinical and metabolic status in patients with type 2 diabetes'. doi:10.1016/j.ctim.2020.102367 Randomized trial
https://doi.org/10.1016/j.ctim.2020.102367 - Mousavi, S.M., Pizarro, A.B., Akhgarjand, C., Bagheri, A., Persad, E., Karimi, E., Wong, A. and Jayedi, A (2022) 'The effects of Anethum graveolens (dill) supplementation on lipid profile and glycemic control: a systematic review and meta-analysis of randomized controlled trials', 62(21), pp. 5705--5716. doi:10.1080/10408398.2021.1889459 Meta-analysis / review
https://doi.org/10.1080/10408398.2021.1889459 - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:837530-1 Traditional / reference
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:837530-1 - World Health Organization (2007) 'WHO monographs on selected medicinal plants, Volume 3: ‘Fructus Anethi'. Available at: https://e-lactancia.org/media/papers/Fitoterapia-Plantas-WHO-03_2007.pdf Traditional / reference
https://e-lactancia.org/media/papers/Fitoterapia-Plantas-WHO-03_2007.pdf - Aydogmus-Ozturk, F. and Jahan, H. and Ozturk, M. and Gunaydin, K. and Choudhary, M.I (2020) 'Preclinical study of the medicinal plants for the treatment of malignant melanoma', Molecular Biology Reports, 47(8), pp. 5975-5983. doi:10.1007/s11033-020-05671-5 Preclinical
https://doi.org/10.1007/s11033-020-05671-5 - Tavakkol Afshari, H.S. and Homayouni Tabrizi, M. and Ardalan, T. and Jalili Anoushirvani, N. and Mahdizadeh, R (2021) 'Anethum graveolens Essential Oil Nanoemulsions (AGEO-NE) as an Exclusive Apoptotic Inducer in Human Lung Adenocarcinoma (A549) Cells', Nutrition and Cancer, 74(4), pp. 1411-1419. doi:10.1080/01635581.2021.1952450 Preclinical
https://doi.org/10.1080/01635581.2021.1952450 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Washington State University Extension, Yakima County (2025) 'One Invasive, One Native, Both Deadly'. Available at: https://extension.wsu.edu/yakima/2025/08/09/one-invasive-one-native-both-deadly/ Traditional / reference
https://extension.wsu.edu/yakima/2025/08/09/one-invasive-one-native-both-deadly/ - King County Noxious Weeds (2024) 'Poison hemlock (Conium maculatum) identification and control'. Available at: https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock Traditional / reference
https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock - Dayan, A.D (2024) 'Death of Socrates: a likely case of poison hemlock (Conium maculatum) poisoning', Clinical Toxicology (Philadelphia, Pa.), 62(1), pp. 56-60. doi:10.1080/15563650.2024.2309328 Clinical study
https://doi.org/10.1080/15563650.2024.2309328 - Grow Forage Cook Ferment 'Poison Hemlock: How to Identify and Potential Look-alikes'. Available at: https://www.growforagecookferment.com/poison-hemlock/ Traditional / reference
https://www.growforagecookferment.com/poison-hemlock/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.