Plant Comparison
Ground Elder vs Corn Silk
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Ground Elder and Corn Silk: they share 6 indicated uses (arthritis / joint pain, inflammation (general), skin irritation, …); 2 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Ground Elder | Corn Silk | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
| Swelling / fluid retention | 1/10 | 1/10 | Comparable evidence |
| Urinary support | 1/10 | 1/10 | Comparable evidence |
| Urinary tract infection (UTI) | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Falcarindiol, a potent COX-1 inhibitor (IC50 0.3 microM), identified as a key anti-inflammatory constituent underlying the plant's traditional anti-rheumatic and analgesic use.
Contribute to the plant's antioxidant activity.
Minor aromatic and coumarin constituents of the aerial parts.
Major antioxidant constituents of corn silk; maysin is the predominant flavonoid quantified in standardised extracts.
Contribute to antioxidant and anti-inflammatory activity.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from anti-rheumatic action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from anti-inflammatory action
inferred from anticancer action
Soothing demulcent for urinary-tract irritation and mild urinary infections; supports kidney function
inferred from anti-inflammatory action
inferred from demulcent action
Diuretic - increases urine output to support the urinary tract and mild fluid retention/swelling; in conscious rats the aqueous extract is diuretic and kaliuretic and modifies glomerular filtration and potassium excretion
inferred from diuretic action
Diuretic - increases urine output to support the urinary tract and mild fluid retention/swelling; in conscious rats the aqueous extract is diuretic and kaliuretic and modifies glomerular filtration and potassium excretion; Soothing demulcent for urinary-tract irritation and mild urinary infections; supports kidney function
Safety, Cautions & Contraindications
Generally safe as a food plant when young leaves are harvested. Contains furocoumarins (photosensitising compounds) — handling large quantities in bright sunlight may cause skin irritation. Individuals with Apiaceae allergies should exercise caution. Not recommended in therapeutic doses during pregnancy.
As a diuretic it should be taken with plenty of fluids; use caution alongside prescription diuretics or medicines that affect potassium.
May lower blood sugar and blood pressure, so use caution with antidiabetic or antihypertensive medication; avoid concentrated medicinal doses in pregnancy - a high-dose standardised extract increased pre-implantation losses in pregnant rats (no fetal malformations were seen).
External Ids
Botanical Description
Vigorous, low, patch-forming perennial herb spreading rapidly by white, brittle, creeping rhizomes. The leaves are broad and twice-ternate (in threes of threes), with oval, sharply toothed leaflets, borne on long stalks. In summer it sends up hollow, grooved, unspotted green stems topped with flat umbels of small white flowers, typical of the carrot family. The whole plant smells mildly of parsley or carrot when crushed.[1]
Tall, robust annual grass with broad, strap-like leaves and a stout, jointed stem. Male flowers form a terminal tassel; female flowers develop on the ear (cob), each floret bearing a single long, silky style and stigma ('corn silk') that protrudes from the husk to catch pollen.[11]
Habitat
A common weed of gardens, hedgerows, shaded waste ground and disturbed soil, often near old dwellings; native to Europe and temperate Asia and widely naturalised elsewhere, where its invasive spreading rhizomes make it a persistent garden weed.[1]
Cultivated worldwide as a major cereal food crop in warm-temperate to tropical climates on fertile, well-drained soils; not found wild, having been domesticated from a wild grass ancestor (teosinte) in Mesoamerica.[11]
Harvesting
The young leaves and stems are gathered in spring, before flowering, when they are most tender and least bitter; the root can be dug at the same time. Careful identification against poisonous Apiaceae look-alikes (poison hemlock, hemlock water-dropwort, fool's parsley) is essential before harvesting.[1]
The silky stigmas and styles are collected from the ears in mid- to late summer, just before or as pollination occurs, while still fresh and pale, then dried quickly to preserve colour and flavonoid content.[11]
Traditional Uses
Ground elder has long been used in European folk medicine as a remedy for gout and rheumatic and arthritic joint pain (reflected in the name 'podagraria', from podagra, gout), typically applied as a poultice or taken as a decoction. The young leaves have also been eaten as a spring pot-herb, valued for their nutrient content as well as their medicinal reputation.[1]
Corn silk has a long traditional use across Chinese, Native American and European folk medicine as a gentle diuretic and soothing demulcent for urinary tract complaints, mild fluid retention and kidney support.[11]
Preparations
Dried or fresh leaf, stem and root simmered in water as a traditional remedy for gout and rheumatic pain.
Fresh leaves crushed or boiled and applied directly to gouty or arthritic joints.
Young spring leaves eaten as a cooked pot-herb, similarly to spinach, continuing the traditional food-medicine use.
Dried corn silk infused in hot water as a traditional diuretic and urinary-support tea.
References
Lookalikes Review
Dangerous Lookalikes
Not documented
References & Sources
- Dębia, K., Dzięcioł, M., Wróblewska, A. and Janda-Milczarek, K (2025) 'Goutweed (Aegopodium podagraria L.): An Edible Weed with Health-Promoting Properties', Molecules, 30(7), pp. 1603. doi:10.3390/molecules30071603 Traditional / reference
https://doi.org/10.3390/molecules30071603 - Engelhardt, L., Pöhnl, T. and Neugart, S (2022) 'Edible Wild Vegetables Urtica dioica L. and Aegopodium podagraria L.: Antioxidants Affected by Processing', Plants (Basel), 11(20), pp. 2710. doi:10.3390/plants11202710 Preclinical
https://doi.org/10.3390/plants11202710 - Jakubczyk, K., Łukomska, A., Czaplicki, S., Wajs-Bonikowska, A., Gutowska, I. et al (2021) 'Bioactive Compounds in Aegopodium podagraria Leaf Extracts and Their Effects against Fluoride-Modulated Oxidative Stress in the THP-1 Cell Line', Pharmaceuticals (Basel), 14(12), pp. 1334. doi:10.3390/ph14121334 Preclinical
https://doi.org/10.3390/ph14121334 - Tovchiga, O.V (2016) 'The influence of goutweed (Aegopodium podagraria L.) tincture and metformin on the carbohydrate and lipid metabolism in dexamethasone-treated rats', BMC Complementary and Alternative Medicine, 16, pp. 235. doi:10.1186/s12906-016-1221-y Preclinical
https://doi.org/10.1186/s12906-016-1221-y - Flieger, J. and Flieger, M (2020) 'The [DPPH/DPPH-H]-HPLC-DAD Method on Tracking the Antioxidant Activity of Pure Antioxidants and Goutweed (Aegopodium podagraria L.) Hydroalcoholic Extracts', Molecules, 25(24), pp. 6005. doi:10.3390/molecules25246005 Preclinical
https://doi.org/10.3390/molecules25246005 - Prior, R.M., Lundgaard, N.H., Light, M.E., Stafford, G.I., van Staden, J. and Jager, A.K (2007) 'The polyacetylene falcarindiol with COX-1 activity isolated from Aegopodium podagraria L', Journal of Ethnopharmacology, 113(1), pp. 176-178. doi:10.1016/j.jep.2007.05.005 Preclinical
https://doi.org/10.1016/j.jep.2007.05.005 - Niziol-Lukaszewska, Z., Zagorska-Dziok, M., Ziemlewska, A. and Bujak, T (2020) 'Comparison of the Antiaging and Protective Properties of Plants from the Apiaceae Family', Oxidative Medicine and Cellular Longevity, 2020, pp. 5307614. doi:10.1155/2020/5307614 Preclinical
https://doi.org/10.1155/2020/5307614 - Baranauskiene, R., Rackauskiene, I. and Venskutonis, P.R (2025) 'Characterization of Steam Volatiles and Evaluation of the Antioxidant Properties of Different Extracts from Leaves and Roots of Aegopodium podagraria L', Molecules, 30(24), pp. 4786. doi:10.3390/molecules30244786 Preclinical
https://doi.org/10.3390/molecules30244786 - Ojala, T., Vuorela, P., Kiviranta, J., Vuorela, H. and Hiltunen, R (1999) 'A bioassay using Artemia salina for detecting phototoxicity of plant coumarins', Planta Medica, 65(8), pp. 715-718. doi:10.1055/s-1999-14049 Preclinical
https://doi.org/10.1055/s-1999-14049 - Schulte, K.E. and Wulfhorst, G (1977) 'Polyacetylene compounds from Aegopodium podagraria L', Archiv der Pharmazie, 310(4), pp. 285-298. doi:10.1002/ardp.19773100403 Preclinical
https://doi.org/10.1002/ardp.19773100403 - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Moerman, D.E (1998) 'Native American Ethnobotany'. Traditional / reference
https://scholar.google.com/scholar?q=Native%20American%20Ethnobotany - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Dayan, A.D (2024) 'Death of Socrates: a likely case of poison hemlock (Conium maculatum) poisoning', Clinical Toxicology (Philadelphia, Pa.), 62(1), pp. 56-60. doi:10.1080/15563650.2024.2309328 Clinical study
https://doi.org/10.1080/15563650.2024.2309328 - King County Noxious Weeds (2024) 'Poison hemlock (Conium maculatum) identification and control'. Available at: https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock Traditional / reference
https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock - Mitchell, M.I. and Routledge, P.A (1978) 'Hemlock water dropwort poisoning - a review', Clinical Toxicology, 12(4), pp. 417-26. doi:10.3109/15563657809150012 Clinical study
https://doi.org/10.3109/15563657809150012 - Teuscher, E. and Greger, H. and Adrian, V (1990) 'Toxicity of Aethusa cynapium L. (fool's parsley)', Pharmazie, 45(7), pp. 537-8. Available at: https://pubmed.ncbi.nlm.nih.gov/2236201/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/2236201/ - Minnesota Wildflowers (2024) 'Aethusa cynapium (Fool's Parsley)'. Available at: https://www.minnesotawildflowers.info/flower/fools-parsley Traditional / reference
https://www.minnesotawildflowers.info/flower/fools-parsley
- Zhang, Y., Wu, L., Ma, Z., Cheng, J. and Liu, J (2018) 'Corn silk (Zea mays L.), a source of natural antioxidants with alpha-amylase, alpha-glucosidase, advanced glycation and diabetic nephropathy inhibitory activities', Biomedicine & Pharmacotherapy, 110, pp. 510-517. doi:10.1016/j.biopha.2018.11.126 Preclinical
https://doi.org/10.1016/j.biopha.2018.11.126 - Wang, Y. and others (2023) 'Corn Silk Flavonoids Ameliorate Hyperuricemia via PI3K/AKT/NF-kappaB Pathway', Journal of Agricultural and Food Chemistry, 71(26), pp. 9968-9979. doi:10.1021/acs.jafc.3c03422 Preclinical
https://doi.org/10.1021/acs.jafc.3c03422 - Habtemariam, S (1998) 'Extract of corn silk (stigma of Zea mays) inhibits the tumour necrosis factor-alpha- and bacterial lipopolysaccharide-induced cell adhesion and ICAM-1 expression', Planta Medica, 64(4), pp. 314-318. doi:10.1055/s-2006-957441 Preclinical
https://doi.org/10.1055/s-2006-957441 - Chen, M.Y., Wu, J.M. and others (2025) 'Unlocking Corn Silk's Potential: Bioactive Compounds Targeting Age-Related Diseases', Molecular Nutrition & Food Research, 69(10), pp. e70117. doi:10.1002/mnfr.70117 Meta-analysis / review
https://doi.org/10.1002/mnfr.70117 - Li, Y. and others (2023) 'Diterpenoid and phenolic constituents from corn silk (Zea mays) with PTP1B inhibitory activity', Natural Product Research, 37(24), pp. 4189-4196. doi:10.1080/14786419.2023.2265038 Preclinical
https://doi.org/10.1080/14786419.2023.2265038 - Wang, B. and others (2019) 'Corn Silk (Zea mays) Induced Apoptosis in Human Breast Cancer (MCF-7) Cells via the ROS-Mediated Mitochondrial Pathway', Oxidative Medicine and Cellular Longevity, 2019, pp. 9789241. doi:10.1155/2019/9789241 Preclinical
https://doi.org/10.1155/2019/9789241 - Guo, J. and others (2024) 'Extraction, purification, structural characteristics, and pharmacological activities of the polysaccharides from corn silk: A review', International Journal of Biological Macromolecules, 274, pp. 133433. doi:10.1016/j.ijbiomac.2024.133433 Meta-analysis / review
https://doi.org/10.1016/j.ijbiomac.2024.133433 - Li, X. and others (2025) 'Ultrasound-assisted extraction of anti-inflammatory actives from corn silk (Zea mays L.): Process optimization, machine learning screening, and interaction mechanisms', Ultrasonics Sonochemistry, 118, pp. 107420. doi:10.1016/j.ultsonch.2025.107420 Preclinical
https://doi.org/10.1016/j.ultsonch.2025.107420 - Wang, Y. and others (2024) 'An Umbrella Insight into the Phytochemistry Features and Biological Activities of Corn Silk: A Narrative Review', Molecules, 29(4), pp. 891. doi:10.3390/molecules29040891 Meta-analysis / review
https://doi.org/10.3390/molecules29040891 - Zhang, W. and others (2023) 'Acidic polysaccharide from corn silk: Structural & conformational properties and hepatoprotective activity', International Journal of Biological Macromolecules, 237, pp. 123851. doi:10.1016/j.ijbiomac.2023.123851 Preclinical
https://doi.org/10.1016/j.ijbiomac.2023.123851 - Hasanudin, K., Hashim, P. and Mustafa, S (2012) 'Corn Silk (Stigma Maydis) in Healthcare: A Phytochemical and Pharmacological Review', Molecules. doi:10.3390/molecules171112937 Traditional / reference
https://doi.org/10.3390/molecules171112937 - Caixeta, G.A.B. and dos Santos Reis, D. and Soares, K.I. and de Brito Ramos, I. and Mendes, G.H.L. and others (2025) 'Toxicological Assessment of a Standardized Dry Extract of Zea mays L. (Poaceae) Stigmas During Gestation: Effects on Maternal Parameters and Fetal Outcomes in Wistar Rats', Birth Defects Research, 117(9). doi:10.1002/bdr2.2526 Traditional / reference
https://doi.org/10.1002/bdr2.2526 - Velazquez, D.V.O. and Xavier, H.S. and Batista, J.E.M. and de Castro-Chaves, C (2005) 'Zea mays L. extracts modify glomerular function and potassium urinary excretion in conscious rats', Phytomedicine, 12(5), pp. 363--369. doi:10.1016/j.phymed.2003.12.010 Traditional / reference
https://doi.org/10.1016/j.phymed.2003.12.010
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.