Plant Comparison
Ground Elder vs Lesser Burdock
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Ground Elder and Lesser Burdock: they share 6 indicated uses (arthritis / joint pain, inflammation (general), skin irritation, …); 2 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Ground Elder | Lesser Burdock | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
| Swelling / fluid retention | 1/10 | 1/10 | Comparable evidence |
| Urinary support | 1/10 | 1/10 | Comparable evidence |
| Urinary tract infection (UTI) | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Falcarindiol, a potent COX-1 inhibitor (IC50 0.3 microM), identified as a key anti-inflammatory constituent underlying the plant's traditional anti-rheumatic and analgesic use.
Contribute to the plant's antioxidant activity.
Minor aromatic and coumarin constituents of the aerial parts.
The major storage carbohydrate; a prebiotic fibre.
Anti-inflammatory and antioxidant constituents.
Antimicrobial and antioxidant constituents.
Pharmacological Actions
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
Lesser burdock (Arctium minus) leaf, flower and root extracts (rich in arctiin/arctigenin and chlorogenic acid) are cytotoxic to breast and liver cancer cells, including multidrug-resistant tumour lines (preclinical).
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from anti-rheumatic action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
Sebaceous-gland regulator - helps balance skin oil (acne); Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
Arctium minus extracts show dose-dependent cytotoxicity against MCF-7 and MDA-MB-231 breast cancer and HepG2 liver cancer cells and are active against both sensitive and multidrug-resistant tumour cell lines (preclinical).
Mild diuretic supporting elimination ('detox', traditional); Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
Safety, Cautions & Contraindications
Generally safe as a food plant when young leaves are harvested. Contains furocoumarins (photosensitising compounds) — handling large quantities in bright sunlight may cause skin irritation. Individuals with Apiaceae allergies should exercise caution. Not recommended in therapeutic doses during pregnancy.
As a member of the daisy family (Asteraceae), it can cause allergic reactions in people sensitive to ragweed and related plants. The high inulin content can cause temporary bloating or gas.
May lower blood sugar (caution with antidiabetic medicines) and add to diuretics; avoid medicinal doses in pregnancy.
External Ids
Botanical Description
Vigorous, low, patch-forming perennial herb spreading rapidly by white, brittle, creeping rhizomes. The leaves are broad and twice-ternate (in threes of threes), with oval, sharply toothed leaflets, borne on long stalks. In summer it sends up hollow, grooved, unspotted green stems topped with flat umbels of small white flowers, typical of the carrot family. The whole plant smells mildly of parsley or carrot when crushed.[1]
Biennial herb closely related to greater burdock, forming a first-year rosette of large, heart-shaped, long-stalked leaves, green above and grey-woolly beneath, generally smaller than Arctium lappa. In the second year it produces a branching flowering stem with smaller purple thistle-like flower heads in a looser, more sprawling habit, each enclosed in a globe of hooked bracts that ripen into clinging burrs.[15]
Habitat
A common weed of gardens, hedgerows, shaded waste ground and disturbed soil, often near old dwellings; native to Europe and temperate Asia and widely naturalised elsewhere, where its invasive spreading rhizomes make it a persistent garden weed.[1]
A common weed of waste ground, roadsides, hedgerows and disturbed soil; native to Europe and widely naturalised in North America, where it is often the most common wild burdock species.[15]
Harvesting
The young leaves and stems are gathered in spring, before flowering, when they are most tender and least bitter; the root can be dug at the same time. Careful identification against poisonous Apiaceae look-alikes (poison hemlock, hemlock water-dropwort, fool's parsley) is essential before harvesting.[1]
The root is dug at the end of the first growing season or early in the second spring, before flowering; leaf may be gathered through the first year. Careful identification against deadly nightshade, whose root can resemble burdock, is essential before digging.[15]
Traditional Uses
Ground elder has long been used in European folk medicine as a remedy for gout and rheumatic and arthritic joint pain (reflected in the name 'podagraria', from podagra, gout), typically applied as a poultice or taken as a decoction. The young leaves have also been eaten as a spring pot-herb, valued for their nutrient content as well as their medicinal reputation.[1]
Preparations
Dried or fresh leaf, stem and root simmered in water as a traditional remedy for gout and rheumatic pain.
Fresh leaves crushed or boiled and applied directly to gouty or arthritic joints.
Young spring leaves eaten as a cooked pot-herb, similarly to spinach, continuing the traditional food-medicine use.
References
Lookalikes Review
Dangerous Lookalikes
References & Sources
- Dębia, K., Dzięcioł, M., Wróblewska, A. and Janda-Milczarek, K (2025) 'Goutweed (Aegopodium podagraria L.): An Edible Weed with Health-Promoting Properties', Molecules, 30(7), pp. 1603. doi:10.3390/molecules30071603 Traditional / reference
https://doi.org/10.3390/molecules30071603 - Engelhardt, L., Pöhnl, T. and Neugart, S (2022) 'Edible Wild Vegetables Urtica dioica L. and Aegopodium podagraria L.: Antioxidants Affected by Processing', Plants (Basel), 11(20), pp. 2710. doi:10.3390/plants11202710 Preclinical
https://doi.org/10.3390/plants11202710 - Jakubczyk, K., Łukomska, A., Czaplicki, S., Wajs-Bonikowska, A., Gutowska, I. et al (2021) 'Bioactive Compounds in Aegopodium podagraria Leaf Extracts and Their Effects against Fluoride-Modulated Oxidative Stress in the THP-1 Cell Line', Pharmaceuticals (Basel), 14(12), pp. 1334. doi:10.3390/ph14121334 Preclinical
https://doi.org/10.3390/ph14121334 - Tovchiga, O.V (2016) 'The influence of goutweed (Aegopodium podagraria L.) tincture and metformin on the carbohydrate and lipid metabolism in dexamethasone-treated rats', BMC Complementary and Alternative Medicine, 16, pp. 235. doi:10.1186/s12906-016-1221-y Preclinical
https://doi.org/10.1186/s12906-016-1221-y - Flieger, J. and Flieger, M (2020) 'The [DPPH/DPPH-H]-HPLC-DAD Method on Tracking the Antioxidant Activity of Pure Antioxidants and Goutweed (Aegopodium podagraria L.) Hydroalcoholic Extracts', Molecules, 25(24), pp. 6005. doi:10.3390/molecules25246005 Preclinical
https://doi.org/10.3390/molecules25246005 - Prior, R.M., Lundgaard, N.H., Light, M.E., Stafford, G.I., van Staden, J. and Jager, A.K (2007) 'The polyacetylene falcarindiol with COX-1 activity isolated from Aegopodium podagraria L', Journal of Ethnopharmacology, 113(1), pp. 176-178. doi:10.1016/j.jep.2007.05.005 Preclinical
https://doi.org/10.1016/j.jep.2007.05.005 - Niziol-Lukaszewska, Z., Zagorska-Dziok, M., Ziemlewska, A. and Bujak, T (2020) 'Comparison of the Antiaging and Protective Properties of Plants from the Apiaceae Family', Oxidative Medicine and Cellular Longevity, 2020, pp. 5307614. doi:10.1155/2020/5307614 Preclinical
https://doi.org/10.1155/2020/5307614 - Baranauskiene, R., Rackauskiene, I. and Venskutonis, P.R (2025) 'Characterization of Steam Volatiles and Evaluation of the Antioxidant Properties of Different Extracts from Leaves and Roots of Aegopodium podagraria L', Molecules, 30(24), pp. 4786. doi:10.3390/molecules30244786 Preclinical
https://doi.org/10.3390/molecules30244786 - Ojala, T., Vuorela, P., Kiviranta, J., Vuorela, H. and Hiltunen, R (1999) 'A bioassay using Artemia salina for detecting phototoxicity of plant coumarins', Planta Medica, 65(8), pp. 715-718. doi:10.1055/s-1999-14049 Preclinical
https://doi.org/10.1055/s-1999-14049 - Schulte, K.E. and Wulfhorst, G (1977) 'Polyacetylene compounds from Aegopodium podagraria L', Archiv der Pharmazie, 310(4), pp. 285-298. doi:10.1002/ardp.19773100403 Preclinical
https://doi.org/10.1002/ardp.19773100403 - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Moerman, D.E (1998) 'Native American Ethnobotany'. Traditional / reference
https://scholar.google.com/scholar?q=Native%20American%20Ethnobotany - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Dayan, A.D (2024) 'Death of Socrates: a likely case of poison hemlock (Conium maculatum) poisoning', Clinical Toxicology (Philadelphia, Pa.), 62(1), pp. 56-60. doi:10.1080/15563650.2024.2309328 Clinical study
https://doi.org/10.1080/15563650.2024.2309328 - King County Noxious Weeds (2024) 'Poison hemlock (Conium maculatum) identification and control'. Available at: https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock Traditional / reference
https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock - Mitchell, M.I. and Routledge, P.A (1978) 'Hemlock water dropwort poisoning - a review', Clinical Toxicology, 12(4), pp. 417-26. doi:10.3109/15563657809150012 Clinical study
https://doi.org/10.3109/15563657809150012 - Teuscher, E. and Greger, H. and Adrian, V (1990) 'Toxicity of Aethusa cynapium L. (fool's parsley)', Pharmazie, 45(7), pp. 537-8. Available at: https://pubmed.ncbi.nlm.nih.gov/2236201/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/2236201/ - Minnesota Wildflowers (2024) 'Aethusa cynapium (Fool's Parsley)'. Available at: https://www.minnesotawildflowers.info/flower/fools-parsley Traditional / reference
https://www.minnesotawildflowers.info/flower/fools-parsley
- Ahangarpour, A., Heidari, H., Oroojan, A.A., Mirzavandi, F., Nasr Esfehani, K. and Dehghan Mohammadi, Z (2017) 'Antidiabetic, hypolipidemic and hepatoprotective effects of Arctium lappa root's hydro-alcoholic extract on nicotinamide-streptozotocin induced type 2 model of diabetes in male mice', Avicenna Journal of Phytomedicine, 7(2), pp. 169-179. Available at: https://pubmed.ncbi.nlm.nih.gov/28348972/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/28348972/ - Gao, Q., Yang, M. and Zuo, Z (2018) 'Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L', Acta Pharmacologica Sinica, 39(5), pp. 787-801. doi:10.1038/aps.2018.32 Traditional / reference
https://doi.org/10.1038/aps.2018.32 - Zeng, F., Li, Y., Zhang, X., Shen, L., Zhao, X. et al (2023) 'Immune regulation and inflammation inhibition of Arctium lappa L. polysaccharides by TLR4/NF-κB signaling pathway in cells', International Journal of Biological Macromolecules, 254, pp. 127700. doi:10.1016/j.ijbiomac.2023.127700 Preclinical
https://doi.org/10.1016/j.ijbiomac.2023.127700 - Fischer, S.P.M., Brusco, I., Camponogara, C., Piana, M., Faccin, H., Gobo, L.A., de Carvalho, L.M. and Oliveira, S.M (2017) 'Arctium minus crude extract presents antinociceptive effect in a mice acute gout attack model', Inflammopharmacology, 26(2), pp. 505-519. doi:10.1007/s10787-017-0384-6 Preclinical
https://doi.org/10.1007/s10787-017-0384-6 - Erdemoglu, N., Turan, N.N., Akkol, E.K., Sener, B. and Abacioglu, N (2008) 'Estimation of anti-inflammatory, antinociceptive and antioxidant activities of Arctium minus (Hill) Bernh. ssp. minus', Journal of Ethnopharmacology, 121(2), pp. 318-323. doi:10.1016/j.jep.2008.11.009 Preclinical
https://doi.org/10.1016/j.jep.2008.11.009 - Ilgun, S., Karatoprak, G.S., Polat, D.C., Safak, E.K., Yildiz, G., Kupeli Akkol, E. and Sobarzo-Sanchez, E (2022) 'Phytochemical Composition and Biological Activities of Arctium minus (Hill) Bernh.: A Potential Candidate as Antioxidant, Enzyme Inhibitor, and Cytotoxic Agent', Antioxidants, 11(10), pp. 1852. doi:10.3390/antiox11101852 Preclinical
https://doi.org/10.3390/antiox11101852 - Erol, E., Erol, K.F., Yanikoglu, R.S., Taskin, C., Kizilarslan Hancer, C. and Topcu, G (2024) 'Quantitative Determination of the Cytotoxic Compounds in Different Organs of Arctium minus (Hill) Bernh. by LC-HRESIMS Using Response Surface Methodology', ACS Omega, 9(40), pp. 41890-41903. doi:10.1021/acsomega.4c06644 Preclinical
https://doi.org/10.1021/acsomega.4c06644 - Malanik, M., Farkova, V., Krizova, J., Kresova, A., Smejkal, K., Kasparovsky, T. and Dadakova, K (2024) 'Comparison of Metabolic Profiles of Fruits of Arctium lappa, Arctium minus, and Arctium tomentosum', Plant Foods for Human Nutrition, 79(2), pp. 497-502. doi:10.1007/s11130-024-01175-w Preclinical
https://doi.org/10.1007/s11130-024-01175-w - Cimino, C.V., Colombo, M.L., Liggieri, C., Bruno, M. and Vairo-Cavalli, S (2015) 'Partial Molecular Characterization of Arctium minus Aspartylendopeptidase and Preparation of Bioactive Peptides by Whey Protein Hydrolysis', Journal of Medicinal Food, 18(8), pp. 856-864. doi:10.1089/jmf.2014.0101 Preclinical
https://doi.org/10.1089/jmf.2014.0101 - Kenny, O., Smyth, T.J., Walsh, D., Kelleher, C.T., Hewage, C.M. and Brunton, N.P (2014) 'Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts', Food Chemistry, 161, pp. 79-86. doi:10.1016/j.foodchem.2014.03.126 Preclinical
https://doi.org/10.1016/j.foodchem.2014.03.126 - Karadeniz, A., Alexie, G., Greten, H.J., Andersch, K. and Efferth, T (2015) 'Cytotoxicity of medicinal plants of the West-Canadian Gwich'in Native Americans towards sensitive and multidrug-resistant cancer cells', Journal of Ethnopharmacology, 168, pp. 191-200. doi:10.1016/j.jep.2015.03.052 Preclinical
https://doi.org/10.1016/j.jep.2015.03.052 - Watkins, F., Pendry, B., Sanchez-Medina, A. and Corcoran, O (2012) 'Antimicrobial assays of three native British plants used in Anglo-Saxon medicine for wound healing formulations in 10th century England', Journal of Ethnopharmacology, 144(2), pp. 408-415. doi:10.1016/j.jep.2012.09.031 Preclinical
https://doi.org/10.1016/j.jep.2012.09.031 - Abraham, E.P. and Crowfoot, D.M (1946) 'An antibacterial substance from Arctium minus and Onopordon tauricum', Nature, 158(4021), pp. 744. doi:10.1038/158744a0 Preclinical
https://doi.org/10.1038/158744a0 - Cavallito, C.J. and Kirchner, F.K (1947) 'The antibacterial principle of Arctium minus; the unsaturated lactone structure', Journal of the American Chemical Society, 69(12), pp. 3030-3032. doi:10.1021/ja01204a028 Preclinical
https://doi.org/10.1021/ja01204a028 - Herbal Reality (n.d.) 'Burdock (Arctium): Benefits, Medicinal Uses, Safety'. Available at: https://www.herbalreality.com/herb/burdock/ Traditional / reference
https://www.herbalreality.com/herb/burdock/ - Drugs.com (n.d.) 'Burdock Uses, Benefits & Dosage'. Available at: https://www.drugs.com/npp/burdock.html Traditional / reference
https://www.drugs.com/npp/burdock.html - Chan, Y.S., Cheng, L.N., Wu, J.H., Chan, E., Kwan, Y.W., Lee, S.M.Y., Leung, G.P.H., Yu, P.H.F. and Chan, S.W (2011) 'A review of the pharmacological effects of Arctium lappa (burdock)', Inflammopharmacology, 19(5), pp. 245--254. doi:10.1007/s10787-010-0062-4 Traditional / reference
https://doi.org/10.1007/s10787-010-0062-4 - Bryson, P.D. and Watanabe, A.S. and Rumack, B.H. and Murphy, R.C (1978) 'Burdock root tea poisoning. Case report involving a commercial preparation', JAMA, 239(20), pp. 2157. Available at: https://pubmed.ncbi.nlm.nih.gov/642161/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/642161/ - Berdai, M.A. and Labib, S. and Chetouani, K. and Harandou, M (2012) 'Atropa belladonna intoxication: a case report', Pan African Medical Journal, 11, pp. 72. Available at: https://pubmed.ncbi.nlm.nih.gov/22655106/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/22655106/ - Oerlemans, C. and de Vries, I. and van Riel, A.J.H.P (2017) 'Anticholinergic syndrome caused by contaminated herbal tea; acting swiftly to identify the source', Nederlands Tijdschrift voor Geneeskunde, 161, pp. D1261. Available at: https://pubmed.ncbi.nlm.nih.gov/28612694/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/28612694/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.