Plant Comparison
Yarrow vs Bearberry
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Yarrow and Bearberry: they share 7 indicated uses (cancer (anticancer research), diarrhoea, infection (general), …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Yarrow | Bearberry | Verdict |
|---|---|---|---|
| Cancer (anticancer research) | 2/10 | 2/10 | Comparable evidence |
| Diarrhoea | 1/10 | 1/10 | Comparable evidence |
| Infection (general) | 1/10 | 6/10 | Stronger for Bearberry |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
| Urinary support | 1/10 | 6/10 | Stronger for Bearberry |
| Urinary tract infection (UTI) | 1/10 | 6/10 | Stronger for Bearberry |
| Wounds | 1/10 | 6/10 | Stronger for Bearberry |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Chamazulene (blue colour), sabinene, 1,8-cineole, camphor and alpha-bisabolol.
Antioxidant and antispasmodic flavonoids.
Contribute to anti-inflammatory and astringent activity.
Compounds traditionally linked to the haemostatic (styptic) effect.
Hydroquinone glycoside; hydrolysed and excreted as antibacterial hydroquinone in the urine.
Up to ~20%; responsible for the astringency and for gastric irritation at high doses.
Pharmacological Actions
Preclinical antiproliferative activity of yarrow flavonoids and sesquiterpenoids (e.g. centaureidin, casticin) against human tumour cell lines.
Bitter digestive tonic (stimulates appetite and bile flow)
Arbutin, the hydroquinone glucoside characteristic of bearberry (Arctostaphylos uva-ursi), shows antiproliferative and pro-apoptotic activity across multiple cancer types (preclinical).
Antibacterial in the urinary tract (arbutin is converted to antibacterial hydroquinone, favoured by alkaline urine); Urinary antiseptic for mild, uncomplicated lower urinary tract infection / cystitis (short-term)
Traditional & Indicated Uses
inferred from bitter-tonic action
inferred from anti-inflammatory action
inferred from vulnerary action
Antiproliferative activity of Achillea millefolium extracts and constituents (centaureidin, casticin) against HeLa, MCF-7 and A431 cancer cell lines (preclinical).
Diaphoretic (supports the body during colds and fevers)
Diaphoretic (supports the body during colds and fevers)
inferred from styptic action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
The bearberry constituent arbutin suppresses osteosarcoma proliferation, migration and invasion via miR-338-3p/MTHFD1L and AKT/mTOR inactivation, and has documented anticancer potential against bladder, breast, colon, liver and other cancers (preclinical).
Urinary antiseptic for mild, uncomplicated lower urinary tract infection / cystitis (short-term)
inferred from astringent action
inferred from urinary-antiseptic action
Antibacterial in the urinary tract (arbutin is converted to antibacterial hydroquinone, favoured by alkaline urine); Urinary antiseptic for mild, uncomplicated lower urinary tract infection / cystitis (short-term)
Safety, Cautions & Contraindications
Generally very safe. Rarely causes contact dermatitis in sensitive individuals (sesquiterpene lactones, same Asteraceae family). Avoid high doses during pregnancy (emmenagogue at large doses). May increase photosensitivity. Allergic reactions uncommon but possible in those sensitive to Asteraceae plants.
Duke (2002) rates yarrow as ++ with clinical evidence (score 2) for antibacterial, antiseptic, antispasmodic, choleretic, aperitif, and astringent activities, consistent with Commission E (KOM) approval for loss of appetite and dyspeptic ailments. Yarrow contains achillin, achilleic acid, and apigenin — compounds with anti-inflammatory and hemostatic properties. Traditional use for wound healing, fever management, and digestive complaints is well-supported. Dose: 2–4 g dried herb as tea three times daily. Caution: yarrow belongs to the Asteraceae family and can cause allergic reactions in sensitive individuals; rare contact dermatitis from sesquiterpene lactones has been reported. Contraindicated in pregnancy due to potential emmenagogue effects (Duke, 2002).
As a member of the daisy family (Asteraceae) it can cause allergic reactions or contact dermatitis in sensitive people, and handling the fresh plant in sunlight can occasionally cause photosensitivity.
Medicinal use is traditionally avoided in pregnancy (can stimulate the uterus and influence menstruation); caution while breastfeeding.
May interact with anticoagulant, sedative and blood-pressure medications and with drugs metabolised by the liver; seek professional advice if on regular medication.
Correct identification is essential, as several poisonous white-flowered umbellifers can be confused with yarrow; clinical evidence in humans is limited.
Short-term use only: not for more than 1 week at a time and not more than about 5 times per year. If symptoms persist beyond ~4 days, worsen, or are accompanied by fever, blood in the urine or pain, seek medical care.
Contraindicated in pregnancy and breastfeeding and not for use in children or adolescents under 18 years.
External Ids
Botanical Description
Aromatic, rhizomatous perennial herb with erect, grooved, softly hairy stems arising in clumps from a creeping rootstock. The leaves are alternate, 2-3-pinnately dissected into narrow feathery segments, giving the whole plant a soft, fern-like texture (hence 'millefolium', thousand-leaved). Numerous small white to pale-pink flower heads are borne in dense, flat-topped compound corymbs at the stem tips. The plant has a sweet, herbaceous, slightly medicinal aroma when crushed.[12]
Low, mat-forming evergreen shrub with trailing, woody stems that root as they spread. The leaves are small, leathery, spatula-shaped (spoon-shaped), glossy dark green above and paler beneath, with a smooth, untoothed margin and a rounded tip. Small, urn-shaped, pink-and-white flowers hang in short clusters in spring, followed by bright red, mealy berries.[11]
Habitat
A common plant of grassland, meadows, roadsides, pastures and waste ground on a wide range of soils; native throughout Europe and temperate Asia and now naturalised across North America, Australia and New Zealand.[12]
Grows on dry, acidic, sandy or rocky ground in open woodland, heath, moorland and mountain slopes across the northern hemisphere (Europe, Asia and North America), often in exposed, cold, upland or subarctic sites.[11]
Harvesting
The flowering aerial parts (leaf, stem and flower) are cut as the flat-topped corymbs open, in mid- to late summer, and dried quickly in a warm, shaded, airy place to preserve the essential oil and colour.[12]
The leaves are gathered in autumn to early spring (outside the flowering and fruiting season), when arbutin content is at its highest, and dried carefully to preserve the glycoside.[11]
Traditional Uses
Yarrow has an ancient reputation as a wound herb (its old name 'staunchweed' and its association with Achilles reflect traditional use to stop bleeding and heal wounds) and as a bitter digestive and diaphoretic remedy for feverish colds, spasmodic gastrointestinal complaints, hepatobiliary disorders and gynaecological complaints. The flowering herb is classically taken as a hot infusion at the onset of a cold or fever to promote sweating, and used as a bitter tonic to stimulate appetite and digestion.[2, 12]
Bearberry leaf is a long-established European folk and official (EU herbal monograph) remedy for mild, uncomplicated lower urinary tract infections and cystitis, used short-term as a urinary antiseptic; it has also been used traditionally as an astringent for mild diarrhoea.[11]
Preparations
Dried flowering herb infused in hot water as a bitter digestive and diaphoretic tea, traditionally taken hot at the onset of colds and fevers.
Tincture of the herb, ethanol 45% V/V, 2-4 ml three times daily. The EU herbal monograph gives the ethanol strength but states no drug-extract ratio, so no 1:5 ratio is claimed here. Educational reference only, not a prescription.
Fresh crushed leaf or flowering tops applied directly to minor cuts and wounds, reflecting the traditional styptic (bleeding-stopping) and vulnerary use.
Steam-distilled from the flowering tops; the chamazulene-rich blue oil is used in low dilution for its anti-inflammatory action.
Dried leaf macerated in cold water for several hours, which extracts less tannin (reducing gastric irritation) than a hot infusion; the preferred traditional preparation.
Dried leaf infused or lightly decocted in hot water; alkalinising the urine (e.g. with dietary measures) is traditionally recommended alongside use, since arbutin's antibacterial action requires alkaline urine.
Dosage
The EU herbal monograph gives 1.5-4 g of the comminuted herb in 150-250 mL of boiling water as an infusion, three or four times daily between meals; for loss of appetite the liquid preparations are taken 30 minutes before meals. Educational reference only, not a prescription.
The EU herbal monograph gives 2-4 mL three times daily in adolescents, adults and elderly. Educational reference only, not a prescription.
The EU herbal monograph describes traditional use of about 3 g dried leaf per cup, up to four times daily, for no more than one week at a time and no more than about five times a year. Educational reference only, not a prescription.
References
Lookalikes Review
Dangerous Lookalikes
References & Sources
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https://doi.org/10.1016/j.heliyon.2023.e22841 - Akram, M (2013) 'Minireview on Achillea millefolium Linn', The Journal of Membrane Biology, 246(9), pp. 661-663. doi:10.1007/s00232-013-9588-x Meta-analysis / review
https://doi.org/10.1007/s00232-013-9588-x - Benedek, B. and Kopp, B (2007) 'Achillea millefolium L. s.l. revisited: recent findings confirm the traditional use', Wiener Medizinische Wochenschrift, 157(13-14), pp. 312-314. doi:10.1007/s10354-007-0431-9 Meta-analysis / review
https://doi.org/10.1007/s10354-007-0431-9 - Li, H., Li, J., Liu, M., Xie, R., Zang, Y., Li, J. and Aisa, H.A (2021) 'Guaianolide sesquiterpene lactones from Achillea millefolium L', Phytochemistry, 186, pp. 112733. doi:10.1016/j.phytochem.2021.112733 Preclinical
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https://www.ema.europa.eu/en/documents/herbal-opinion/final-european-union-herbal-monograph-achillea-millefolium-l-herba-revision-1_en.pdf - Herbal Reality (n.d.) 'Yarrow (Achillea millefolium): Benefits, Uses, Safety'. Available at: https://www.herbalreality.com/herb/yarrow/ Traditional / reference
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https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Villanueva-Bermejo, D. et al (2017) 'Chemical composition and antioxidant activity of Achillea millefolium', pp. 469--476. Traditional / reference
https://scholar.google.com/scholar?q=Chemical%20composition%20and%20antioxidant%20activity%20of%20Achillea%20millefolium - Csupor-Loffler, B. and Hajdu, Z. and Zupko, I. and Rethy, B. and Falkay, G. and Forgo, P. and Hohmann, J (2009) 'Antiproliferative effect of flavonoids and sesquiterpenoids from Achillea millefolium s.l. on cultured human tumour cell lines', Phytotherapy Research, 23(5), pp. 672-676. doi:10.1002/ptr.2697 Preclinical
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https://doi.org/10.1002/2211-5463.13024 - Gagyor, I., Hummers, E., Schmiemann, G., Friede, T., Pfeiffer, S., Afshar, K. and Bleidorn, J (2021) 'Herbal treatment with uva ursi extract versus fosfomycin in women with uncomplicated urinary tract infection in primary care: a randomized controlled trial', Clinical Microbiology and Infection, 27(10), pp. 1441--1447. doi:10.1016/j.cmi.2021.05.032 Randomized trial
https://doi.org/10.1016/j.cmi.2021.05.032 - Moore, M., Trill, J., Simpson, C., Webley, F., Radford, M., Stanton, L. and others (2019) 'Uva-ursi extract and ibuprofen as alternative treatments for uncomplicated urinary tract infection in women (ATAFUTI): a factorial randomized trial', Clinical Microbiology and Infection, 25(8), pp. 973--980. doi:10.1016/j.cmi.2019.01.011 Randomized trial
https://doi.org/10.1016/j.cmi.2019.01.011 - ScienceDirect Topics (pharmacognosy) 'Arctostaphylos Uva-Ursi - an overview'. Available at: https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/arctostaphylos-uva-ursi Traditional / reference
https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/arctostaphylos-uva-ursi - North Carolina Extension Gardener Plant Toolbox 'Buxus sempervirens (Common Boxwood)'. Available at: https://plants.ces.ncsu.edu/plants/buxus-sempervirens/ Traditional / reference
https://plants.ces.ncsu.edu/plants/buxus-sempervirens/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.