Plant Comparison

Yarrow vs Bearberry

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant AYarrowAchillea millefoliumAsteraceaeFull monograph →
Plant BBearberryArctostaphylos uva-ursiEricaceaeFull monograph →

At a glance

Yarrow and Bearberry: they share 7 indicated uses (cancer (anticancer research), diarrhoea, infection (general), …); 3 pharmacological actions in common.

YarrowBearberry
Constituents43
Pharmacological actions124
Indicated uses197
Safety notes73
Cited sources3621
Indicated uses
Only Yarrow
Loss of appetiteArthritis / joint painBloatingBruisingCold & fluFeverHeavy menstrual bleedingIndigestionInflammation (general)Menstrual crampsMuscle spasmSwelling / fluid retention
Shared (7)
Cancer (anticancer research)DiarrhoeaInfection (general)Skin irritationUrinary supportUrinary tract infection (UTI)Wounds
Only Bearberry
none
Pharmacological actions
Only Yarrow
Anti-inflammatoryAntioxidantAntispasmodicBitter digestive tonic / stomachicDiaphoreticDigestive aidDiureticStyptic / haemostaticVulnerary (wound healing)
Shared (3)
Anticancer (preclinical)AntimicrobialAstringent
Only Bearberry
Urinary antiseptic

Evidence face-off — shared uses

ConditionYarrowBearberryVerdict
Cancer (anticancer research)2/102/10Comparable evidence
Diarrhoea1/101/10Comparable evidence
Infection (general)1/106/10Stronger for Bearberry
Skin irritation1/101/10Comparable evidence
Urinary support1/106/10Stronger for Bearberry
Urinary tract infection (UTI)1/106/10Stronger for Bearberry
Wounds1/106/10Stronger for Bearberry

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Essential oil (mono- and sesquiterpenes)[12]

Chamazulene (blue colour), sabinene, 1,8-cineole, camphor and alpha-bisabolol.

SesquiterpenesEssential (volatile) oilChamazuleneAlpha-bisabololCamphor1,8-Cineole (eucalyptol)
Flavonoids (apigenin, luteolin, rutin, quercetin)[12]

Antioxidant and antispasmodic flavonoids.

FlavonoidsQuercetinApigeninLuteolinRutin
Sesquiterpene lactones, phenolic acids, tannins and coumarins[12]

Contribute to anti-inflammatory and astringent activity.

Sesquiterpene lactonesPhenolic acidsSesquiterpenesCoumarinsTannins
Betonicine and achilleine[12]

Compounds traditionally linked to the haemostatic (styptic) effect.

Arbutin (and methylarbutin)[6, 7, 9, 11, 12, 13]

Hydroquinone glycoside; hydrolysed and excreted as antibacterial hydroquinone in the urine.

Glycosides
Tannins (gallotannins)[11, 14]

Up to ~20%; responsible for the astringency and for gastric irritation at high doses.

Tannins
Flavonoids and phenolic acids[4, 5, 6, 14, 15]

Antioxidant constituents of the leaf.

Phenolic acidsFlavonoids

Pharmacological Actions

Anti-inflammatory[1, 2, 3, 4, 5, 6, 7, 8, 15, 16, 17]
Anticancer (preclinical)[12, 18, 19]

Preclinical antiproliferative activity of yarrow flavonoids and sesquiterpenoids (e.g. centaureidin, casticin) against human tumour cell lines.

Antimicrobial[15, 16, 17]
Antioxidant[1, 9, 11, 15, 16, 17]
Antispasmodic[3, 15, 16, 17]

Antispasmodic (cramp easing)

Astringent[12, 14]
Bitter digestive tonic / stomachic[12, 14]

Bitter digestive tonic (stimulates appetite and bile flow)

Diaphoretic[12, 14]

Diaphoretic (supports the body during colds and fevers)

Digestive aid[2, 9, 12, 14]

Bitter digestive tonic (stimulates appetite and bile flow)

Diuretic[15, 16, 17]
Styptic / haemostatic[10, 12, 14, 20]

Styptic / haemostatic (slows bleeding from minor cuts)

Vulnerary (wound healing)[12, 15, 16, 17, 21]

Vulnerary (wound healing)

Anticancer (preclinical)[16, 17]

Arbutin, the hydroquinone glucoside characteristic of bearberry (Arctostaphylos uva-ursi), shows antiproliferative and pro-apoptotic activity across multiple cancer types (preclinical).

Antimicrobial[1, 7, 10, 11, 12, 18, 19]

Antibacterial in the urinary tract (arbutin is converted to antibacterial hydroquinone, favoured by alkaline urine); Urinary antiseptic for mild, uncomplicated lower urinary tract infection / cystitis (short-term)

Astringent[11, 14]

Astringent (tannins)

Urinary antiseptic[7, 11, 12, 18, 19]

Antibacterial in the urinary tract (arbutin is converted to antibacterial hydroquinone, favoured by alkaline urine); Urinary antiseptic for mild, uncomplicated lower urinary tract infection / cystitis (short-term)

Traditional & Indicated Uses

Loss of appetite[12, 14]Traditional · 1/10

inferred from bitter-tonic action

Evidence: 1
Label: Loss of appetite
Arthritis / joint pain[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bloating[12, 14]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Bruising[12, 15, 16, 17, 21]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Cancer (anticancer research)[12, 18, 19]Traditional · 2/10

Antiproliferative activity of Achillea millefolium extracts and constituents (centaureidin, casticin) against HeLa, MCF-7 and A431 cancer cell lines (preclinical).

Evidence: 2
Label: Cancer (anticancer research)
Cold & flu[12, 14]Traditional · 1/10

Diaphoretic (supports the body during colds and fevers)

Evidence: 1
Label: Cold & flu
Diarrhoea[12, 14]Traditional · 1/10

inferred from astringent action

Evidence: 1
Label: Diarrhoea
Fever[12, 14]Traditional · 1/10

Diaphoretic (supports the body during colds and fevers)

Evidence: 1
Label: Fever
Heavy menstrual bleeding[12, 14, 20]Traditional · 1/10

inferred from styptic action

Evidence: 1
Label: Heavy menstrual bleeding
Indigestion[12, 14]Traditional · 1/10

inferred from bitter-tonic action

Evidence: 1
Label: Indigestion
Infection (general)[15, 16, 17]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Menstrual cramps[15, 16, 17]Traditional · 1/10
Evidence: 1
Label: Menstrual cramps
Muscle spasm[15, 16, 17]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Muscle spasm
Skin irritation[15, 16, 17]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Swelling / fluid retention[15, 16, 17]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Swelling / fluid retention
Urinary support[15, 16, 17]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Urinary support
Urinary tract infection (UTI)[15, 16, 17]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Urinary tract infection (UTI)
Wounds[12, 14, 20]Traditional · 1/10

Styptic / haemostatic (slows bleeding from minor cuts)

Evidence: 1
Label: Wounds
Cancer (anticancer research)[16, 17]Traditional · 2/10

The bearberry constituent arbutin suppresses osteosarcoma proliferation, migration and invasion via miR-338-3p/MTHFD1L and AKT/mTOR inactivation, and has documented anticancer potential against bladder, breast, colon, liver and other cancers (preclinical).

Evidence: 2
Label: Cancer (anticancer research)
Diarrhoea[11, 14]Traditional · 1/10

inferred from astringent action

Evidence: 1
Label: Diarrhoea
Infection (general)[7, 11, 18, 19]Moderate · 6/10

Urinary antiseptic for mild, uncomplicated lower urinary tract infection / cystitis (short-term)

Evidence: 6
Label: Infection (general)
Skin irritation[11, 14]Traditional · 1/10

inferred from astringent action

Evidence: 1
Label: Skin irritation
Urinary support[7, 8, 11, 12, 18, 19]Moderate · 6/10

inferred from urinary-antiseptic action

Evidence: 6
Label: Urinary support
Urinary tract infection (UTI)[7, 11, 12, 18, 19]Moderate · 6/10

Antibacterial in the urinary tract (arbutin is converted to antibacterial hydroquinone, favoured by alkaline urine); Urinary antiseptic for mild, uncomplicated lower urinary tract infection / cystitis (short-term)

Evidence: 6
Label: Urinary tract infection (UTI)
Wounds[7, 11, 12, 18, 19]Moderate · 6/10

inferred from antimicrobial action

Evidence: 6
Label: Wounds

Safety, Cautions & Contraindications

Safety note[15, 16, 17]Caution

Generally very safe. Rarely causes contact dermatitis in sensitive individuals (sesquiterpene lactones, same Asteraceae family). Avoid high doses during pregnancy (emmenagogue at large doses). May increase photosensitivity. Allergic reactions uncommon but possible in those sensitive to Asteraceae plants.

Safety note[15, 16, 17, 22]Caution

Duke (2002) rates yarrow as ++ with clinical evidence (score 2) for antibacterial, antiseptic, antispasmodic, choleretic, aperitif, and astringent activities, consistent with Commission E (KOM) approval for loss of appetite and dyspeptic ailments. Yarrow contains achillin, achilleic acid, and apigenin — compounds with anti-inflammatory and hemostatic properties. Traditional use for wound healing, fever management, and digestive complaints is well-supported. Dose: 2–4 g dried herb as tea three times daily. Caution: yarrow belongs to the Asteraceae family and can cause allergic reactions in sensitive individuals; rare contact dermatitis from sesquiterpene lactones has been reported. Contraindicated in pregnancy due to potential emmenagogue effects (Duke, 2002).

Safety note[12]Info

As a member of the daisy family (Asteraceae) it can cause allergic reactions or contact dermatitis in sensitive people, and handling the fresh plant in sunlight can occasionally cause photosensitivity.

Safety note[14]Caution

Medicinal use is traditionally avoided in pregnancy (can stimulate the uterus and influence menstruation); caution while breastfeeding.

Safety note[12]Caution

May interact with anticoagulant, sedative and blood-pressure medications and with drugs metabolised by the liver; seek professional advice if on regular medication.

Safety note[12, 23]Info

Correct identification is essential, as several poisonous white-flowered umbellifers can be confused with yarrow; clinical evidence in humans is limited.

Safety note[24, 25, 26, 27, 28, 29, 30, 31, 32, 33]Info

Additional omniasana.bio sources cited for Achillea millefolium (identification, distribution, foraging, traditional use and supporting evidence; see bibliography).

Safety note[11]Info

Short-term use only: not for more than 1 week at a time and not more than about 5 times per year. If symptoms persist beyond ~4 days, worsen, or are accompanied by fever, blood in the urine or pain, seek medical care.

Safety note[11]Caution

Contraindicated in pregnancy and breastfeeding and not for use in children or adolescents under 18 years.

Safety note[7, 11, 12]Serious

Works best when the urine is alkaline; avoid taking with substances that acidify the urine. The hydroquinone released can be irritant/potentially hepatotoxic, so prolonged or repeated use must be avoided.

External Ids

Gbif: 3120060
Wikidata: Q25408
Gbif: 2882580
Wikidata: Q208032

Botanical Description

Aromatic, rhizomatous perennial herb with erect, grooved, softly hairy stems arising in clumps from a creeping rootstock. The leaves are alternate, 2-3-pinnately dissected into narrow feathery segments, giving the whole plant a soft, fern-like texture (hence 'millefolium', thousand-leaved). Numerous small white to pale-pink flower heads are borne in dense, flat-topped compound corymbs at the stem tips. The plant has a sweet, herbaceous, slightly medicinal aroma when crushed.[12]

Height: 20-100 cm (occasionally to 1 m)
Habit: Erect, rhizomatous, mat-forming perennial herb
Leaves: Alternate, 2-3-pinnately dissected into narrow feathery segments; aromatic when crushed
Flowers: Small white to pale pink flower heads in dense, flat-topped compound corymbs
Stem: Erect, grooved, softly hairy/woolly, plain green (never purple-blotched)
Root: Creeping, fibrous rhizome
Fruit: Small flattened achenes without pappus
Flowering Period: June-September

Low, mat-forming evergreen shrub with trailing, woody stems that root as they spread. The leaves are small, leathery, spatula-shaped (spoon-shaped), glossy dark green above and paler beneath, with a smooth, untoothed margin and a rounded tip. Small, urn-shaped, pink-and-white flowers hang in short clusters in spring, followed by bright red, mealy berries.[11]

Height: 5-30 cm (trailing/prostrate)
Habit: Low, mat-forming, trailing evergreen shrub
Leaves: Small, leathery, spatula-shaped, glossy dark green above, entire (untoothed) margin, rounded tip
Flowers: Small, urn-shaped, pink-and-white, in short drooping clusters
Stem: Trailing, woody, rooting as it spreads
Root: Woody, fibrous roots along trailing stems
Fruit: Bright red, mealy berry
Flowering Period: April-June

Habitat

A common plant of grassland, meadows, roadsides, pastures and waste ground on a wide range of soils; native throughout Europe and temperate Asia and now naturalised across North America, Australia and New Zealand.[12]

Grows on dry, acidic, sandy or rocky ground in open woodland, heath, moorland and mountain slopes across the northern hemisphere (Europe, Asia and North America), often in exposed, cold, upland or subarctic sites.[11]

Harvesting

The flowering aerial parts (leaf, stem and flower) are cut as the flat-topped corymbs open, in mid- to late summer, and dried quickly in a warm, shaded, airy place to preserve the essential oil and colour.[12]

Parts: Flower, Leaf, Stem
Season: Summer, at full flower (June-September)

The leaves are gathered in autumn to early spring (outside the flowering and fruiting season), when arbutin content is at its highest, and dried carefully to preserve the glycoside.[11]

Parts: Leaf
Season: Autumn to early spring

Traditional Uses

Yarrow has an ancient reputation as a wound herb (its old name 'staunchweed' and its association with Achilles reflect traditional use to stop bleeding and heal wounds) and as a bitter digestive and diaphoretic remedy for feverish colds, spasmodic gastrointestinal complaints, hepatobiliary disorders and gynaecological complaints. The flowering herb is classically taken as a hot infusion at the onset of a cold or fever to promote sweating, and used as a bitter tonic to stimulate appetite and digestion.[2, 12]

Bearberry leaf is a long-established European folk and official (EU herbal monograph) remedy for mild, uncomplicated lower urinary tract infections and cystitis, used short-term as a urinary antiseptic; it has also been used traditionally as an astringent for mild diarrhoea.[11]

Preparations

Infusion[12]

Dried flowering herb infused in hot water as a bitter digestive and diaphoretic tea, traditionally taken hot at the onset of colds and fevers.

Tincture[13]

Tincture of the herb, ethanol 45% V/V, 2-4 ml three times daily. The EU herbal monograph gives the ethanol strength but states no drug-extract ratio, so no 1:5 ratio is claimed here. Educational reference only, not a prescription.

Poultice/compress[10, 12]

Fresh crushed leaf or flowering tops applied directly to minor cuts and wounds, reflecting the traditional styptic (bleeding-stopping) and vulnerary use.

Essential oil[12]

Steam-distilled from the flowering tops; the chamazulene-rich blue oil is used in low dilution for its anti-inflammatory action.

Cold infusion (maceration)[11]

Dried leaf macerated in cold water for several hours, which extracts less tannin (reducing gastric irritation) than a hot infusion; the preferred traditional preparation.

Infusion/decoction[11]

Dried leaf infused or lightly decocted in hot water; alkalinising the urine (e.g. with dietary measures) is traditionally recommended alongside use, since arbutin's antibacterial action requires alkaline urine.

Dosage

Dried herb infusion[13, 14]

The EU herbal monograph gives 1.5-4 g of the comminuted herb in 150-250 mL of boiling water as an infusion, three or four times daily between meals; for loss of appetite the liquid preparations are taken 30 minutes before meals. Educational reference only, not a prescription.

Tincture (ethanol 45% V/V)[13]

The EU herbal monograph gives 2-4 mL three times daily in adolescents, adults and elderly. Educational reference only, not a prescription.

Infusion[11]

The EU herbal monograph describes traditional use of about 3 g dried leaf per cup, up to four times daily, for no more than one week at a time and no more than about five times a year. Educational reference only, not a prescription.

References

REF-2076, REF-2077, REF-2078, REF-2079, REF-2080, REF-2081, REF-2082, REF-2083, REF-2084, REF-2085, REF-2086
REF-2370, REF-2371, REF-2372, REF-2373, REF-2374, REF-2375, REF-0406, REF-2376, REF-2377, REF-2378

Lookalikes Review

Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Dangerous Lookalikes

Safety note[34, 35, 36]Fatal
Dangerous Plant: conium-maculatum
Confused Part: Young feathery, finely divided leaves gathered for tea, salad or medicine; poison hemlock's young leaves are also feathery and finely divided.
Confusion Context: Yarrow (Achillea millefolium) is foraged for its soft, feathery, fern-like leaves. As Grow Forage Cook Ferment warns, yarrow is sometimes mistaken for poison hemlock (Conium maculatum), which is very toxic - hemlock contains coniine and kills by ascending paralysis and respiratory failure, and a few leaves can be fatal. Young hemlock leaves are more feathery and can resemble yarrow before the plant grows tall. Because yarrow is a popular forage and hemlock is widespread, this is a potentially fatal confusion.
Distinguishing Features: SMELL: yarrow smells sweet and herbaceous, often likened to fresh pine or a pleasant medicinal scent. Poison hemlock smells rank and musty/mousy., Stem: yarrow has a solid, green, slightly hairy/woolly grooved stem with no purple. Poison hemlock has a hairless stem conspicuously blotched and streaked with red-purple, especially near the base., Leaf and size: yarrow leaves are soft, very finely divided and feathery on a low plant (usually under 60 cm). Poison hemlock is a tall (1.5-3 m) branching biennial with larger, glossy, more open fern-like leaves.
Key Test: Check the stem and smell. A solid green (often woolly) stem with soft feathery leaves and a sweet pine-like herbaceous scent = yarrow. A hairless stem with red-purple blotches and a musty/mousy smell = poison hemlock - deadly, do not put it to your mouth. If the stem is purple-blotched or the smell is musty, do not use it.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Safety note[20, 21]Dangerous
Dangerous Plant: buxus-sempervirens
Confused Part: Small leathery evergreen leaves gathered as the medicinal 'uva-ursi'; the poisonous leaves of box look similar and have been used to adulterate bearberry.
Confusion Context: Bearberry (Arctostaphylos uva-ursi) leaves are collected as a urinary herb. As documented in pharmacognosy, during collection bearberry is commonly confused with cowberry (edible) and with box (Buxus sempervirens), and poisonous box - which lacks bearberry's active arbutin - has occasionally been used to adulterate the drug. Box leaves are poisonous, containing steroidal alkaloids that cause vomiting, diarrhoea, dizziness and, in quantity, convulsions and respiratory failure. Because the small leathery evergreen leaves are similar, box is a genuine toxic adulterant/look-alike of bearberry.
Distinguishing Features: Leaf apex (decisive): bearberry leaves are spatulate with an entire (untoothed) margin and a rounded apex. Box leaves have a small notch cut out at the tip (emarginate)., Leaf underside: box leaves have a loose, separable epidermis on the underside and lack the astringency of bearberry; bearberry leaves are firm and astringent with a net of sunken veins., Source: buy uva-ursi only from suppliers who authenticate the leaf, since adulteration with box cannot be judged casually.
Key Test: Check the leaf tip. Bearberry leaves are spoon-shaped with a smooth margin and a ROUNDED tip. A leaf with a notch cut out of the tip (and a loose skin on the underside) is box - poisonous, not bearberry. Use only authenticated uva-ursi.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Farasati Far, B., Behzad, G. and Khalili, H (2023) 'Achillea millefolium: mechanism of action, pharmacokinetic, clinical drug-drug interactions and tolerability', Heliyon, 9(12), pp. e22841. doi:10.1016/j.heliyon.2023.e22841 Meta-analysis / review
    https://doi.org/10.1016/j.heliyon.2023.e22841
  2. Akram, M (2013) 'Minireview on Achillea millefolium Linn', The Journal of Membrane Biology, 246(9), pp. 661-663. doi:10.1007/s00232-013-9588-x Meta-analysis / review
    https://doi.org/10.1007/s00232-013-9588-x
  3. Benedek, B. and Kopp, B (2007) 'Achillea millefolium L. s.l. revisited: recent findings confirm the traditional use', Wiener Medizinische Wochenschrift, 157(13-14), pp. 312-314. doi:10.1007/s10354-007-0431-9 Meta-analysis / review
    https://doi.org/10.1007/s10354-007-0431-9
  4. Li, H., Li, J., Liu, M., Xie, R., Zang, Y., Li, J. and Aisa, H.A (2021) 'Guaianolide sesquiterpene lactones from Achillea millefolium L', Phytochemistry, 186, pp. 112733. doi:10.1016/j.phytochem.2021.112733 Preclinical
    https://doi.org/10.1016/j.phytochem.2021.112733
  5. Li, H., Liu, L., Gou, G., Xin, X., Li, J. and Aisa, H.A (2023) 'Guaianolides from Achillea millefolium L. and their anti-inflammatory activity', Phytochemistry, 210, pp. 113647. doi:10.1016/j.phytochem.2023.113647 Preclinical
    https://doi.org/10.1016/j.phytochem.2023.113647
  6. Li, H., Akber Aisa, H. and Li, J (2023) 'Germacrane-type sesquiterpene lactones from Achillea millefolium L. and their anti-inflammatory activity', Chemistry & Biodiversity, 20(4), pp. e202300079. doi:10.1002/cbdv.202300079 Preclinical
    https://doi.org/10.1002/cbdv.202300079
  7. Li, H., Xu, N., Li, J. and Aisa, H.A (2023) 'Guaianolide-type sesquiterpene lactones from Achillea millefolium L. and their anti-inflammatory activity', Phytochemistry, 216, pp. 113894. doi:10.1016/j.phytochem.2023.113894 Preclinical
    https://doi.org/10.1016/j.phytochem.2023.113894
  8. Huang, X., Xu, N., Liu, Z., Li, H., Lu, H. and Li, J (2024) 'Chemical composition of Achillea millefolium L. and their anti-inflammatory activity', Chemistry & Biodiversity, 21(8), pp. e202400946. doi:10.1002/cbdv.202400946 Preclinical
    https://doi.org/10.1002/cbdv.202400946
  9. Alomair, M.K., Alabduladheem, L.S., Almajed, M.A., Alobaid, A.A., Alkhalifah, E.A.R., Younis, N.S. and Mohamed, M.E (2022) 'Achillea millefolium essential oil mitigates peptic ulcer in rats through Nrf2/HO-1 pathway', Molecules, 27(22), pp. 7908. doi:10.3390/molecules27227908 Preclinical
    https://doi.org/10.3390/molecules27227908
  10. Bagheri, A., Amin, G., Tavangar, S.M., Heidari, M. and Bagheri, J (2024) 'Safety and hemostatic effect of Achillea millefolium L. in localized bleeding', Hepatology Forum, 5(1), pp. 25-27. doi:10.14744/hf.2022.2022.0041 Preclinical
    https://doi.org/10.14744/hf.2022.2022.0041
  11. Ayoobi, F., Shamsizadeh, A., Fatemi, I., Vakilian, A., Allahtavakoli, M., Hassanshahi, G. and Moghadam-Ahmadi, A (2017) 'Bio-effectiveness of the main flavonoids of Achillea millefolium in the pathophysiology of neurodegenerative disorders - a review', Iranian Journal of Basic Medical Sciences, 20(6), pp. 604-612. doi:10.22038/IJBMS.2017.8827 Meta-analysis / review
    https://doi.org/10.22038/IJBMS.2017.8827
  12. Ali, S.I., Gopalakrishnan, B. and Venkatesalu, V (2017) 'Pharmacognosy, Phytochemistry and Pharmacological Properties of Achillea millefolium L.: A Review', 31(8), pp. 1140--1161. doi:10.1002/ptr.5840 Traditional / reference
    https://doi.org/10.1002/ptr.5840
  13. European Medicines Agency (HMPC) (2019) 'European Union herbal monograph on Achillea millefolium L., herba, Revision 1'. Available at: https://www.ema.europa.eu/en/documents/herbal-opinion/final-european-union-herbal-monograph-achillea-millefolium-l-herba-revision-1_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/herbal-opinion/final-european-union-herbal-monograph-achillea-millefolium-l-herba-revision-1_en.pdf
  14. Herbal Reality (n.d.) 'Yarrow (Achillea millefolium): Benefits, Uses, Safety'. Available at: https://www.herbalreality.com/herb/yarrow/ Traditional / reference
    https://www.herbalreality.com/herb/yarrow/
  15. Applequist, W.L. and Moerman, D.E (2011) 'Yarrow (Achillea millefolium L.): a neglected panacea?', 65(2), pp. 209--225. Traditional / reference
    https://scholar.google.com/scholar?q=Yarrow%20%28Achillea%20millefolium%20L.%29%3A%20a%20neglected%20panacea%3F
  16. Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
    https://scholar.google.com/scholar?q=A%20Modern%20Herbal
  17. Villanueva-Bermejo, D. et al (2017) 'Chemical composition and antioxidant activity of Achillea millefolium', pp. 469--476. Traditional / reference
    https://scholar.google.com/scholar?q=Chemical%20composition%20and%20antioxidant%20activity%20of%20Achillea%20millefolium
  18. Csupor-Loffler, B. and Hajdu, Z. and Zupko, I. and Rethy, B. and Falkay, G. and Forgo, P. and Hohmann, J (2009) 'Antiproliferative effect of flavonoids and sesquiterpenoids from Achillea millefolium s.l. on cultured human tumour cell lines', Phytotherapy Research, 23(5), pp. 672-676. doi:10.1002/ptr.2697 Preclinical
    https://doi.org/10.1002/ptr.2697
  19. Papakosta, K. and Grafakou, M.-E. and Barda, C. and Kostopoulos, I.V. and Tsitsilonis, O. and Skaltsa, H (2020) 'Cytotoxicity and Anti-cancer Activity of the Genus Achillea L', Current Medicinal Chemistry, 27(41), pp. 6910-6925. doi:10.2174/0929867327666200505092514 Preclinical
    https://doi.org/10.2174/0929867327666200505092514
  20. Sacred Plant Co (2025) 'Yarrow: The Warrior'. Available at: https://sacredplantco.com/blogs/natures-pharmacy-exploring-the-historical-uses-and-health-benefits-of-medicinal-herbs/the-warrior-s-herb-that-bridged-ancient-legends-and-modern-wound-care Traditional / reference
    https://sacredplantco.com/blogs/natures-pharmacy-exploring-the-historical-uses-and-health-benefits-of-medicinal-herbs/the-warrior-s-herb-that-bridged-ancient-legends-and-modern-wound-care
  21. Hemmati, A.A., Arzi, A. and Amin, M (2002) 'Effect of Achillea millefolium extract in wound healing of rabbit', 2(2), pp. 164--167. Traditional / reference
    https://scholar.google.com/scholar?q=Effect%20of%20Achillea%20millefolium%20extract%20in%20wound%20healing%20of%20rabbit
  22. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  23. First Nature (n.d.) 'Achillea millefolium, Yarrow: identification, distribution, habitat'. Available at: https://www.first-nature.com/flowers/achillea-millefolium.php Traditional / reference
    https://www.first-nature.com/flowers/achillea-millefolium.php
  24. Grieve, M (1931). Available at: https://botanical.com/botanical/mgmh/y/yarrow03.html Traditional / reference
    https://botanical.com/botanical/mgmh/y/yarrow03.html
  25. Jenabi, E. and Fereidoony, B (2015) 'Effect of Achillea millefolium on relief of primary dysmenorrhea: a double-blind randomized clinical trial', 28(5), pp. 402--404. doi:10.1016/j.jpag.2014.12.008 Randomized trial
    https://doi.org/10.1016/j.jpag.2014.12.008
  26. Joybilee Farm (n.d.) 'How to Stop Bleeding with Yarrow Styptic'. Available at: https://joybileefarm.com/how-to-stop-bleeding-yarrow/ Traditional / reference
    https://joybileefarm.com/how-to-stop-bleeding-yarrow/
  27. North Carolina Extension (n.d.) 'Achillea millefolium'. Available at: https://plants.ces.ncsu.edu/plants/achillea-millefolium/ Traditional / reference
    https://plants.ces.ncsu.edu/plants/achillea-millefolium/
  28. Northwest School of Aromatic Medicine (2026) 'Yarrow in Herbal & Aromatic Medicine: History, Uses, and Energetics'. Available at: https://aromaticmedicineschool.com/yarrow-herbal-medicine-history-uses-energetics/ Traditional / reference
    https://aromaticmedicineschool.com/yarrow-herbal-medicine-history-uses-energetics/
  29. Plant Reference (n.d.) 'Achillea millefolium (common yarrow) - Identification & Care Guide'. Available at: https://www.plantref.org/plants/achillea-millefolium Traditional / reference
    https://www.plantref.org/plants/achillea-millefolium
  30. Royal Botanic Gardens, Kew (n.d.) 'Achillea millefolium L'. Available at: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:181164-1 Traditional / reference
    https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:181164-1
  31. Royal Horticultural Society (n.d.) 'Achillea millefolium (common yarrow)'. Available at: https://www.rhs.org.uk/plants/311/achillea-millefolium/details Traditional / reference
    https://www.rhs.org.uk/plants/311/achillea-millefolium/details
  32. The Wildlife Trusts (n.d.). Available at: https://www.wildlifetrusts.org/wildlife-explorer/wildflowers/yarrow Traditional / reference
    https://www.wildlifetrusts.org/wildlife-explorer/wildflowers/yarrow
  33. United States Forest Service (n.d.) 'Common Yarrow (Achillea millefolium)'. Available at: https://www.fs.usda.gov/wildflowers/plant-of-the-week/achillea_millefolium.shtml Traditional / reference
    https://www.fs.usda.gov/wildflowers/plant-of-the-week/achillea_millefolium.shtml
  34. Grow Forage Cook Ferment 'Foraging Yarrow: Identification, Look-alikes, and Uses'. Available at: https://www.growforagecookferment.com/foraging-for-yarrow/ Traditional / reference
    https://www.growforagecookferment.com/foraging-for-yarrow/
  35. Dayan, A.D (2024) 'Death of Socrates: a likely case of poison hemlock (Conium maculatum) poisoning', Clinical Toxicology (Philadelphia, Pa.), 62(1), pp. 56-60. doi:10.1080/15563650.2024.2309328 Clinical study
    https://doi.org/10.1080/15563650.2024.2309328
  36. King County Noxious Weeds (2024) 'Poison hemlock (Conium maculatum) identification and control'. Available at: https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock Traditional / reference
    https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock
  1. Dell'Annunziata, F. and Cometa, S. and Della Marca, R. and Busto, F. and Folliero, V. and Franci, G. and Galdiero, M. and De Giglio, E. and De Filippis, A (2022) 'In Vitro Antibacterial and Anti-Inflammatory Activity of Arctostaphylos uva-ursi Leaf Extract against Cutibacterium acnes', Pharmaceutics, 14(9), pp. 1952. doi:10.3390/pharmaceutics14091952 Preclinical
    https://doi.org/10.3390/pharmaceutics14091952
  2. de Arriba, S.G. and Naser, B. and Nolte, K.U (2013) 'Risk assessment of free hydroquinone derived from Arctostaphylos uva-ursi folium herbal preparations', International Journal of Toxicology, 32(6), pp. 442-453. doi:10.1177/1091581813507721 Preclinical
    https://doi.org/10.1177/1091581813507721
  3. Kravchenko, G. and Krasilnikova, O. and Raal, A. and Mazen, M. and Chaika, N. and Kireyev, I. and Grytsyk, A. and Koshovyi, O (2022) 'Arctostaphylos uva-ursi L. leaves extract and its modified cysteine preparation for the management of insulin resistance: chemical analysis and bioactivity', Natural Products and Bioprospecting, 12(1), pp. 30. doi:10.1007/s13659-022-00352-1 Preclinical
    https://doi.org/10.1007/s13659-022-00352-1
  4. Sugier, P. and Seczyk, L. and Sugier, D. and Krawczyk, R. and Wojcik, M. and Czarnecka, J. and Okon, S. and Plak, A (2021) 'Chemical Characteristics and Antioxidant Activity of Arctostaphylos uva-ursi L. Spreng. at the Southern Border of the Geographical Range of the Species in Europe', Molecules, 26(24), pp. 7692. doi:10.3390/molecules26247692 Preclinical
    https://doi.org/10.3390/molecules26247692
  5. Sugier, P. and Seczyk, L. and Sugier, D (2022) 'Variation in Population and Solvents as Factors Determining the Chemical Composition and Antioxidant Potential of Arctostaphylos uva-ursi (L.) Spreng. Leaf Extracts', Molecules, 27(7), pp. 2247. doi:10.3390/molecules27072247 Preclinical
    https://doi.org/10.3390/molecules27072247
  6. Panusa, A. and Petrucci, R. and Marrosu, G. and Multari, G. and Gallo, F.R (2015) 'UHPLC-PDA-ESI-TOF/MS metabolic profiling of Arctostaphylos pungens and Arctostaphylos uva-ursi. A comparative study of phenolic compounds from leaf methanolic extracts', Phytochemistry, 115, pp. 79-88. doi:10.1016/j.phytochem.2015.01.002 Preclinical
    https://doi.org/10.1016/j.phytochem.2015.01.002
  7. Hudek Turkovic, A., Gunjaca, M., Marjanovic, M., Lovric, M., Butorac, A., Rasic, D., Peraica, M., Vujcic Bok, V., Sola, I., Rusak, G. and Durgo, K (2022) 'Proteome changes in human bladder T24 cells induced by hydroquinone derived from Arctostaphylos uva-ursi herbal preparation', Journal of Ethnopharmacology, pp. 2022. doi:10.1016/j.jep.2022.115092 Traditional / reference
    https://doi.org/10.1016/j.jep.2022.115092
  8. Beaux, D. and Fleurentin, J. and Mortier, F (1999) 'Effect of extracts of Orthosiphon stamineus Benth, Hieracium pilosella L., Sambucus nigra L. and Arctostaphylos uva-ursi (L.) Spreng. in rats', Phytotherapy Research, 13(3), pp. 222-225. doi:10.1002/(SICI)1099-1573(199905)13:3<222::AID-PTR447>3.0.CO;2-P Preclinical
    https://doi.org/10.1002/(SICI)1099-1573(199905)13:3<222::AID-PTR447>3.0.CO;2-P
  9. Seczyk, L. and Sugier, D. and Sugier, P (2024) 'Effect of the Type of Herbal Preparations (Powdered Plant Material vs. Dry Ethanolic Extracts) on the Bioaccessibility of Bearberry (Arctostaphylos uva-ursi (L.) Spreng.) Phytochemicals in Simulated Digestion Conditions', Molecules, 29(24), pp. 5968. doi:10.3390/molecules29245968 Preclinical
    https://doi.org/10.3390/molecules29245968
  10. Wrona, M. and Blasco, S. and Becerril, R. and Nerin, C. and Sales, E. and Asensio, E (2018) 'Antioxidant and antimicrobial markers by UPLC-ESI-Q-TOF-MS of a new multilayer active packaging based on Arctostaphylos uva-ursi', Talanta, 196, pp. 498-509. doi:10.1016/j.talanta.2018.12.057 Preclinical
    https://doi.org/10.1016/j.talanta.2018.12.057
  11. European Medicines Agency (HMPC) (2018) 'European Union herbal monograph on Arctostaphylos uva-ursi (L.) Spreng., folium (Uvae ursi folium)'. Available at: https://www.ema.europa.eu/en/medicines/herbal/uvae-ursi-folium Traditional / reference
    https://www.ema.europa.eu/en/medicines/herbal/uvae-ursi-folium
  12. Braga, V.C.C., Pianetti, G.A. and Cesar, I.C (2020) 'Comparative stability of arbutin in Arctostaphylos uva-ursi by a new comprehensive stability-indicating HPLC method', Phytochemical Analysis, 31(6), pp. 884--891. doi:10.1002/pca.2953 Preclinical
    https://doi.org/10.1002/pca.2953
  13. Qin, D., Liu, J., Guo, W., Ju, T., Fu, S., Liu, D. and Hu, G (2024) 'Arbutin alleviates intestinal colitis by regulating neutrophil extracellular traps formation and microbiota composition', Phytomedicine. doi:10.1016/j.phymed.2024.155741 Preclinical
    https://doi.org/10.1016/j.phymed.2024.155741
  14. ESCOP (European Scientific Cooperative on Phytotherapy) (n.d.) 'Uvae ursi folium (Bearberry Leaf) monograph', pp. com. Available at: https://www.escop.com/downloads/bearberry-leaf/ Traditional / reference
    https://www.escop.com/downloads/bearberry-leaf/
  15. Zhang, B., Zeng, M., Li, B., Kan, Y., Wang, S., Cao, B. and others (2021) 'Arbutin attenuates LPS-induced acute kidney injury by inhibiting inflammation and apoptosis via the PI3K/Akt/Nrf2 pathway', Phytomedicine. doi:10.1016/j.phymed.2021.153466 Preclinical
    https://doi.org/10.1016/j.phymed.2021.153466
  16. Nahar, L. and Al-Groshi, A. and Kumar, A. and Sarker, S.D (2022) 'Arbutin: Occurrence in Plants, and Its Potential as an Anticancer Agent', Molecules, 27(24), pp. 8786. doi:10.3390/molecules27248786 Preclinical
    https://doi.org/10.3390/molecules27248786
  17. Wang, C.-Q. and Wang, X.-M. and Li, B.-L. and Zhang, Y.-M. and Wang, L (2020) 'Arbutin suppresses osteosarcoma progression via miR-338-3p/MTHFD1L and inactivation of the AKT/mTOR pathway', FEBS Open Bio, 11(1), pp. 289-299. doi:10.1002/2211-5463.13024 Preclinical
    https://doi.org/10.1002/2211-5463.13024
  18. Gagyor, I., Hummers, E., Schmiemann, G., Friede, T., Pfeiffer, S., Afshar, K. and Bleidorn, J (2021) 'Herbal treatment with uva ursi extract versus fosfomycin in women with uncomplicated urinary tract infection in primary care: a randomized controlled trial', Clinical Microbiology and Infection, 27(10), pp. 1441--1447. doi:10.1016/j.cmi.2021.05.032 Randomized trial
    https://doi.org/10.1016/j.cmi.2021.05.032
  19. Moore, M., Trill, J., Simpson, C., Webley, F., Radford, M., Stanton, L. and others (2019) 'Uva-ursi extract and ibuprofen as alternative treatments for uncomplicated urinary tract infection in women (ATAFUTI): a factorial randomized trial', Clinical Microbiology and Infection, 25(8), pp. 973--980. doi:10.1016/j.cmi.2019.01.011 Randomized trial
    https://doi.org/10.1016/j.cmi.2019.01.011
  20. ScienceDirect Topics (pharmacognosy) 'Arctostaphylos Uva-Ursi - an overview'. Available at: https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/arctostaphylos-uva-ursi Traditional / reference
    https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/arctostaphylos-uva-ursi
  21. North Carolina Extension Gardener Plant Toolbox 'Buxus sempervirens (Common Boxwood)'. Available at: https://plants.ces.ncsu.edu/plants/buxus-sempervirens/ Traditional / reference
    https://plants.ces.ncsu.edu/plants/buxus-sempervirens/

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.