Symptom → Plant Sources
Yarrow (Achillea millefolium) as a tool for helping with Skin irritation
inferred from anti-inflammatory action
3 sources supporting Yarrow for Skin irritation. Includes scientific publications, books, monographs and traditional-use references.
Mechanistic basis
This use is associated with the plant's anti-inflammatory, astringent actions. Further evidence for that pharmacology:
This review discusses the pharmacodynamics, pharmacokinetics and mechanism of action of Achillea millefolium (yarrow), one of the oldest medicinal botanicals, covering its anti-inflammatory, antioxidant and other pharmacological activities and tolerability.
This minireview summarises the traditional medicinal uses of Achillea millefolium (yarrow) for liver disorders, hepatitis and jaundice and as a digestive bitter, antispasmodic and wound remedy.
Yarrow (Achillea millefolium L. s.l.) is traditionally used for inflammatory and spasmodic gastro-intestinal disorders; this work showed that its flavonoids mediate the antispasmodic properties and dicaffeoylquinic acids the anti-inflammatory effects, confirming the traditional use.
Seven undescribed guaianolide sesquiterpene lactones (millefoliumins A-G) and five known analogues were isolated from the whole plant of Achillea millefolium, characterising the sesquiterpene-lactone constituents of yarrow.
Seven previously undescribed guaianolides (millefolactons A-G) and three known analogues isolated from Achillea millefolium were evaluated for anti-inflammatory activity, supporting the anti-inflammatory use of yarrow.
Six undescribed germacrane-type sesquiterpene lactones (millefoliumons A-F) isolated from Achillea millefolium showed anti-inflammatory activity, supporting the anti-inflammatory use of yarrow.
Seventeen undescribed guaianolide sesquiterpene lactones (millefoliumines A-Q) and seven known analogues isolated from Achillea millefolium were assessed for anti-inflammatory activity, supporting the anti-inflammatory use of yarrow.
Monoterpenes, megastigmanes and other constituents isolated from Achillea millefolium were characterised and evaluated for anti-inflammatory activity, supporting the anti-inflammatory use of yarrow.
Achillea millefoilum L. (Yarrow) is an important species of Asteraceae family with common utilization in traditional medicine of several cultures from Europe to Asia for the treatment of spasmodic gastrointestinal disorders, hepatobiliary, gynecological disorders, against inflammation and for wound healing. An extensive review of literature was made on A. millefoilum L. using ethno botanical text books, published articles in peer-reviewed journals, unpublished materials and scientific databases. The Plant List, International Plant Name Index and Kew Botanical Garden databases were used to authenticate the scientific names. Monoterpenes are the most representative metabolites constituting 90% of the essential oils in relation to the sesquiterpenes, and a wide range of chemical compounds have also been reported. Different pharmacological experiments in many in-vitro and in-vivo models have proved the potential of A. millefoilum with antiinflammatory, antiulcer, anticancer activities etc. lending support to the rationale behind numerous of its traditional uses. Due to the noteworthy pharmacological activities, A. millefoilum will be a better option for new drug discovery. The present review will comprehensively summarize the pharmacognosy, phytochemistry and ethnopharmacology of A. millefoilum reported to date, with emphasis on more in vitro, clinical and pathological studies needed to investigate the unexploited potential of this plant. Copyright © 2017 John Wiley & Sons, Ltd.