Symptom → Plant Sources
Figwort (Scrophularia nodosa) as a tool for helping with Inflammation (general)
inferred from anti-inflammatory action
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Superfine powders (50-180 microns) of four medicinal plants including Scrophularia nodosa significantly inhibited TNF-alpha, IL-1beta, IL-6 and nitric oxide production in LPS-stimulated mouse peripheral blood mononuclear cells by at least 20% more than hydroethanolic extracts, and were more concentrated in phenolics, demonstrating an anti-inflammatory effect.
2 sources supporting Figwort for Inflammation (general). Includes scientific publications, books, monographs and traditional-use references.
Mechanistic basis
This use is associated with the plant's anti-inflammatory action. Further evidence for that pharmacology:
Biological screening of Scrophularia nodosa crude extract and its fractions assessed phytotoxic, cytotoxic, antibacterial, antifungal and analgesic activities. The fractions exhibited significant antibacterial and antifungal effects, the plant was non-toxic in the brine-shrimp assay, and the crude extract showed highly significant analgesic activity (65.6% inhibition at 500 mg/kg in the writhing test).