Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in Hepatocytes
Preclinical
Abstract
The flower bud of Rosa rugosa has a wide range of biological activities. An ethanol extract ameliorated acetaminophen-induced liver injury in hepatocytes by upregulating Sirt1 and potentiating the LKB1/AMPK/Nrf2 antioxidant cascade, demonstrating hepatoprotective and antioxidant activity.
Referenced for these plants
How to cite
Lei, L., Zhu, Y., Gao, W., Du, X. and others (2023) 'Ethanol Extract of Rosa rugosa Ameliorates Acetaminophen-Induced Liver Injury via Upregulating Sirt1 and Subsequent Potentiation of LKB1/AMPK/Nrf2 Cascade in Hepatocytes', Molecules, 28(21), pp. 7307. doi:10.3390/molecules28217307
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