Pharmacological Actions

Anti-inflammatory^{[1, 2, 5, 6, 7, 8]}

Antioxidant^{[1, 2, 4, 5, 6, 7, 8]}

Antispasmodic^{[6, 7, 8]}

Antispasmodic (cramp easing)

Immunomodulator / immune support^{[2, 6, 7, 8]}

Vulnerary (wound healing)^{[1, 6, 7, 8]}

Traditional & Indicated Uses

Arthritis / joint pain^{[6, 7, 8]}Traditional · 1/10

inferred from anti-inflammatory action

more plants for arthritis / joint pain →detailed sources →

Bruising^{[6, 7, 8]}Traditional · 1/10

inferred from vulnerary action

more plants for bruising →detailed sources →

Cold & flu^{[6, 7, 8]}Traditional · 1/10

inferred from immunomodulator action

more plants for cold & flu →detailed sources →

Immune support^{[6, 7, 8]}Traditional · 1/10

more plants for immune support →detailed sources →

Inflammation (general)^{[6, 7, 8]}Traditional · 1/10

inferred from anti-inflammatory action

more plants for inflammation (general) →detailed sources →

Menstrual cramps^{[6, 7, 8]}Traditional · 1/10

inferred from antispasmodic action

more plants for menstrual cramps →detailed sources →

Muscle spasm^{[6, 7, 8]}Traditional · 1/10

inferred from antispasmodic action

more plants for muscle spasm →detailed sources →

Skin irritation^{[6, 7, 8]}Traditional · 1/10

inferred from anti-inflammatory action

more plants for skin irritation →detailed sources →

Wounds^{[6, 7, 8]}Traditional · 1/10

inferred from vulnerary action

more plants for wounds →detailed sources →

Safety, Cautions & Contraindications

Safety note^{[6, 7, 8]}Caution

Generally very safe as a food and in moderate herbal use. Cyanogenic glucosides present in very small amounts — not significant in normal food or tea use. Isoflavones are phytoestrogens (as in red clover) — same precautions apply in hormone-sensitive conditions. Well tolerated by most people.

Safety note^{[6, 7, 8]}Info

Duke (2002) does not include a dedicated entry for white clover (Trifolium repens) in the Handbook of Medicinal Herbs, Second Edition.

References

REF-1323, REF-1324, REF-1325, REF-1326, REF-1327

References & Sources

Ngangom, L., Venugopal, D. and Pandey, N (2024) 'Investigation of Trifolium repens L. from the Indian Himalayan region as a phyto-therapeutic agent', Natural Product Research, 38(24), pp. 4468-4478. doi:10.1080/14786419.2023.2299319 Meta-analysis / review
https://doi.org/10.1080/14786419.2023.2299319
Ahmad, S. and Zeb, A (2020) 'Phytochemical profile and pharmacological properties of Trifolium repens', Journal of Basic and Clinical Physiology and Pharmacology, 32(3), pp. 20200015. doi:10.1515/jbcpp-2020-0015 Meta-analysis / review
https://doi.org/10.1515/jbcpp-2020-0015
Sarno, F., Pepe, G., Termolino, P., Carafa, V. and others (2020) 'Trifolium repens Blocks Proliferation in Chronic Myelogenous Leukemia via the BCR-ABL/STAT5 Pathway', Cells, 9(2), pp. 379. doi:10.3390/cells9020379 Preclinical
https://doi.org/10.3390/cells9020379
Ahmad, S. and Zeb, A (2020) 'Nephroprotective property of Trifolium repens leaf extract against paracetamol-induced kidney damage in mice', 3 Biotech, 10(12), pp. 541. doi:10.1007/s13205-020-02539-0 Preclinical
https://doi.org/10.1007/s13205-020-02539-0
Kolodziejczyk-Czepas, J (2012) 'Trifolium species-derived substances and extracts--biological activity and prospects for medicinal applications', Journal of Ethnopharmacology, 143(1), pp. 14-23. doi:10.1016/j.jep.2012.06.048 Meta-analysis / review
https://doi.org/10.1016/j.jep.2012.06.048
Bhattacharya, S. et al (2013) 'Review of the botanical, phytochemical, pharmacological and toxicological properties of white clover (Trifolium repens L.)', 7(7), pp. 583--588. Traditional / reference
Find this source
Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
Find this source
Klaiber, I. et al (2002) 'Health benefits of isoflavones from clover species', 16(1), pp. 1--8. Traditional / reference
Find this source

Generated June 22, 2026 from omniasana.bio