Omnia Sana · Plant Monograph
Noni
Morinda citrifolia
This monograph compiles 7 pharmacological actions, 12 traditional / indicated uses, supported by 13 cited sources, drawn directly from the Omnia Sana plant database.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
more plants for arthritis / joint pain →detailed sources →inferred from analgesic action
more plants for back pain →detailed sources →inferred from antidiabetic action
more plants for blood sugar / diabetes support →detailed sources →inferred from antiviral action
more plants for cold & flu →detailed sources →inferred from analgesic action
more plants for headache →detailed sources →inferred from antimicrobial action
more plants for infection (general) →detailed sources →inferred from anti-inflammatory action
more plants for inflammation (general) →detailed sources →inferred from antidiabetic action
more plants for metabolic support →detailed sources →inferred from anti-inflammatory action
more plants for skin irritation →detailed sources →inferred from antimicrobial action
more plants for wounds →detailed sources →Safety, Cautions & Contraindications
Generally safe in moderate amounts. High potassium content — use caution in renal disease. Rare cases of hepatotoxicity reported with excessive consumption. May interact with warfarin (due to vitamin K content). Avoid during pregnancy.
Duke (2002) rates noni as +++ and notes analgesic, antirheumatic, antiarthritic, antitumor, antispasmodic, and hypotensive activities at the experimental level (score 1). Traditional Polynesian and South Asian medicine values it as a broad-spectrum tonic. The plant contains morindine, proxeronine, and damnacanthal, which are under investigation for immunomodulatory and anti-tumor effects. Duke notes that noni fruit can be consumed as food and is generally safe, though the juice has a strong unpleasant odor and taste. No significant toxicity has been reported with regular food consumption (Duke, 2002).
References
REF-1417, REF-1418, REF-1419, REF-1420, REF-1421, REF-1422, REF-1423, REF-1424, REF-1425, REF-1426References & Sources
- Potterat, O. and Hamburger, M (2007) 'Morinda citrifolia (Noni) fruit--phytochemistry, pharmacology, safety', Planta Medica, 73(3), pp. 191-199. doi:10.1055/s-2007-967115 Meta-analysis / review
https://doi.org/10.1055/s-2007-967115 - Brown, A.C (2012) 'Anticancer activity of Morinda citrifolia (Noni) fruit: a review', Phytotherapy Research, 26(10), pp. 1427-1440. doi:10.1002/ptr.4595 Meta-analysis / review
https://doi.org/10.1002/ptr.4595 - Almeida-Souza, F., de Souza, C.S., Taniwaki, N.N., Silva, J.J. and others (2016) 'Morinda citrifolia Linn. fruit (Noni) juice induces an increase in NO production and death of Leishmania amazonensis amastigotes in peritoneal macrophages from BALB/c', Nitric Oxide, 58, pp. 51-58. doi:10.1016/j.niox.2016.06.004 Preclinical
https://doi.org/10.1016/j.niox.2016.06.004 - Wang, R., Wang, L., Wang, S., Wang, J. and others (2022) 'Phenolics from noni (Morinda citrifolia L.) fruit alleviate obesity in high fat diet-fed mice via modulating the gut microbiota and mitigating intestinal damage', Food Chemistry, 402, pp. 134232. doi:10.1016/j.foodchem.2022.134232 Preclinical
https://doi.org/10.1016/j.foodchem.2022.134232 - Yoshitomi, H., Zhou, J., Nishigaki, T., Li, W. and others (2020) 'Morinda citrifolia (Noni) fruit juice promotes vascular endothelium function in hypertension via glucagon-like peptide-1 receptor-CaMKKbeta-AMPK-eNOS pathway', Phytotherapy Research, 34(9), pp. 2341-2350. doi:10.1002/ptr.6685 Preclinical
https://doi.org/10.1002/ptr.6685 - Almeida, E.S., de Oliveira, D. and Hotza, D (2019) 'Properties and Applications of Morinda citrifolia (Noni): A Review', Comprehensive Reviews in Food Science and Food Safety, 18(4), pp. 883-909. doi:10.1111/1541-4337.12456 Meta-analysis / review
https://doi.org/10.1111/1541-4337.12456 - Kim, S.H., Seong, G.S. and Choung, S.Y (2020) 'Fermented Morinda citrifolia (Noni) Alleviates DNCB-Induced Atopic Dermatitis in NC/Nga Mice through Modulating Immune Balance and Skin Barrier Function', Nutrients, 12(1), pp. 249. doi:10.3390/nu12010249 Preclinical
https://doi.org/10.3390/nu12010249 - Jin, M.Y., Wu, X.Y., Li, M.Y., Li, X.T. and others (2021) 'Noni (Morinda citrifolia L.) Fruit Polysaccharides Regulated IBD Mice Via Targeting Gut Microbiota: Association of JNK/ERK/NF-kappaB Signaling Pathways', Journal of Agricultural and Food Chemistry, 69(35), pp. 10151-10162. doi:10.1021/acs.jafc.1c03833 Preclinical
https://doi.org/10.1021/acs.jafc.1c03833 - Lee, D., Yu, J.S., Huang, P., Qader, M. and others (2020) 'Identification of Anti-Inflammatory Compounds from Hawaiian Noni (Morinda citrifolia L.) Fruit Juice', Molecules, 25(21), pp. 4968. doi:10.3390/molecules25214968 Preclinical
https://doi.org/10.3390/molecules25214968 - Ma, L.D., Lin, G.B., Yang, L.B., Cao, J.L. and others (2021) 'Morinda citrifolia (Noni) Juice Suppresses A549 Human Lung Cancer Cells via Inhibiting AKT/Nuclear Factor-kappaB Signaling Pathway', Chinese Journal of Integrative Medicine, 27(9), pp. 688-695. doi:10.1007/s11655-020-3421-y Preclinical
https://doi.org/10.1007/s11655-020-3421-y - Hirazumi, A. and Furusawa, E (1999) 'An immunomodulatory polysaccharide-rich substance from the fruit juice of Morinda citrifolia', 13(5), pp. 380--387. Preclinical
Find this source - Potterat, O. and Hamburger, M (2007) 'Morinda citrifolia (Noni) fruit — phytochemistry, pharmacology, safety', 73(3), pp. 191--199. Preclinical
Find this source - West, B.J., Jensen, C.J., Westendorf, J. and White, L.D (2006) 'A safety review of noni fruit juice', 71(8). Traditional / reference
Find this source
Generated June 22, 2026 from omniasana.bio