Omnia Sana · Plant Monograph
Clove
Syzygium aromaticum
This monograph compiles 5 pharmacological actions, 11 traditional / indicated uses, supported by 13 cited sources, drawn directly from the Omnia Sana plant database.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
more plants for arthritis / joint pain →detailed sources →inferred from analgesic action
more plants for back pain →detailed sources →inferred from digestive action
more plants for bloating →detailed sources →inferred from analgesic action
more plants for headache →detailed sources →inferred from digestive action
more plants for indigestion →detailed sources →inferred from antimicrobial action
more plants for infection (general) →detailed sources →inferred from anti-inflammatory action
more plants for inflammation (general) →detailed sources →inferred from anti-inflammatory action
more plants for skin irritation →detailed sources →inferred from antimicrobial action
more plants for wounds →detailed sources →Safety, Cautions & Contraindications
Strong and concentrated: Clove oil is very potent and should always be diluted before skin or mouth use.Dental use: Undiluted clove oil can burn gums or skin.Blood thinning: Clove may increase bleeding risk in large amounts or with anticoagulants.Pregnancy: Culinary amounts are fine; medicinal doses should be used cautiously.Children: Essential oil should be used with extra caution and diluted well.
Duke (2002) rates cloves as +++ with clinical evidence (score 2) for analgesic activity — specifically, topical application of clove oil (eugenol) for dental pain is clinically validated. The plant also shows strong antimicrobial, antifungal (anti-Candida), antispasmodic, and antiviral activities at the experimental level. Commission E approves topical clove preparations for dental pain. Recommended dose: 1–5% clove oil preparation (topical) or 150 mg clove powder internally. The essential oil is irritating to mucous membranes and should not be applied undiluted to skin or mucous membranes (Duke, 2002).
References
REF-1074, REF-1075, REF-1076, REF-1077, REF-1078, REF-1079, REF-1080, REF-1081, REF-1082, REF-1083References & Sources
- Haro-Gonzalez, J.N., Castillo-Herrera, G.A., Martinez-Velazquez, M. and Espinosa-Andrews, H (2021) 'Clove Essential Oil (Syzygium aromaticum L. Myrtaceae): Extraction, Chemical Composition, Food Applications, and Essential Bioactivity for Human Health', Molecules, 26(21), pp. 6387. doi:10.3390/molecules26216387 Meta-analysis / review
https://doi.org/10.3390/molecules26216387 - Batiha, G.E., Alkazmi, L.M., Wasef, L.G., Beshbishy, A.M. and others (2020) 'Syzygium aromaticum L. (Myrtaceae): Traditional Uses, Bioactive Chemical Constituents, Pharmacological and Toxicological Activities', Biomolecules, 10(2), pp. 202. doi:10.3390/biom10020202 Meta-analysis / review
https://doi.org/10.3390/biom10020202 - Vicidomini, C., Roviello, V. and Roviello, G.N (2021) 'Molecular Basis of the Therapeutical Potential of Clove (Syzygium aromaticum L.) and Clues to Its Anti-COVID-19 Utility', Molecules, 26(7), pp. 1880. doi:10.3390/molecules26071880 Meta-analysis / review
https://doi.org/10.3390/molecules26071880 - Irahal, I.N., Guenaou, I., Lahlou, F.A., Hmimid, F. and others (2022) 'Syzygium aromaticum bud (clove) essential oil is a novel and safe aldose reductase inhibitor: in silico, in vitro, and in vivo evidence', Hormones (Athens), 21(2), pp. 229-240. doi:10.1007/s42000-021-00347-6 Preclinical
https://doi.org/10.1007/s42000-021-00347-6 - Yassin, M.T., Mostafa, A.A. and Al-Askar, A.A (2020) 'In vitro anticandidal potency of Syzygium aromaticum (clove) extracts against vaginal candidiasis', BMC Complementary Medicine and Therapies, 20(1), pp. 25. doi:10.1186/s12906-020-2818-8 Preclinical
https://doi.org/10.1186/s12906-020-2818-8 - Kiki, M.J (2023) 'In Vitro Antiviral Potential, Antioxidant, and Chemical Composition of Clove (Syzygium aromaticum) Essential Oil', Molecules, 28(6), pp. 2421. doi:10.3390/molecules28062421 Preclinical
https://doi.org/10.3390/molecules28062421 - Radunz, M., da Trindade, M.L.M., Camargo, T.M., Radunz, A.L. and others (2019) 'Antimicrobial and antioxidant activity of unencapsulated and encapsulated clove (Syzygium aromaticum, L.) essential oil', Food Chemistry, 276, pp. 180-186. doi:10.1016/j.foodchem.2018.09.173 Preclinical
https://doi.org/10.1016/j.foodchem.2018.09.173 - Shakeel, F., Alam, P., Ali, A., Alqarni, M.H. and others (2021) 'Investigating Antiarthritic Potential of Nanostructured Clove Oil (Syzygium aromaticum) in FCA-Induced Arthritic Rats: Pharmaceutical Action and Delivery Strategies', Molecules, 26(23), pp. 7327. doi:10.3390/molecules26237327 Preclinical
https://doi.org/10.3390/molecules26237327 - Tu, Z., Moss-Pierce, T., Ford, P. and Jiang, T.A (2014) 'Syzygium aromaticum L. (Clove) extract regulates energy metabolism in myocytes', Journal of Medicinal Food, 17(9), pp. 1003-1010. doi:10.1089/jmf.2013.0175 Preclinical
https://doi.org/10.1089/jmf.2013.0175 - Banerjee, S., Panda, C.K. and Das, S (2006) 'Clove (Syzygium aromaticum L.), a potential chemopreventive agent for lung cancer', Carcinogenesis, 27(8), pp. 1645-1654. doi:10.1093/carcin/bgi372 Preclinical
https://doi.org/10.1093/carcin/bgi372 - Bhowmik, D., Kumar, K.P.S., Yadav, A., Srivastava, S., Paswan, S. and Dutta, A.S (2012) 'Recent trends in Indian traditional herbs Syzygium aromaticum and its health benefits', 1(1), pp. 13--23. Traditional / reference
Find this source - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - World Health Organization (2002) 'WHO Monographs on Selected Medicinal Plants'. Traditional / reference
Find this source
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