Omnia Sana · Plant Monograph
Angelica
Angelica archangelica
This monograph compiles 3 documented constituents, 11 pharmacological actions, 19 traditional / indicated uses, supported by 8 cited sources, drawn directly from the Omnia Sana plant database.
Key Constituents
Including columbianetin, angelicin, imperatorin and xanthotoxin.
Rich in monoterpenes such as alpha-pinene and beta-phellandrene; gives the aromatic, carminative character.
Pharmacological Actions
Anticonvulsant and cognition-supporting (preclinical)
Carminative and aromatic bitter digestive (indigestion, bloating, flatulence)
Carminative and aromatic bitter digestive (indigestion, bloating, flatulence)
Carminative and aromatic bitter digestive (indigestion, bloating, flatulence)
Anticonvulsant and cognition-supporting (preclinical)
Traditional & Indicated Uses
inferred from gastroprotective action
more plants for acid reflux →detailed sources →Anxiolytic / sedative (anxiety, nervous tension)
more plants for anxiety →detailed sources →inferred from bitter-tonic action
more plants for loss of appetite →detailed sources →inferred from anti-inflammatory action
more plants for arthritis / joint pain →detailed sources →Carminative and aromatic bitter digestive (indigestion, bloating, flatulence)
more plants for bloating →detailed sources →inferred from expectorant action
more plants for bronchitis →detailed sources →inferred from neuroprotective action
more plants for cognitive function →detailed sources →Diaphoretic / expectorant support during colds
more plants for cold & flu →detailed sources →inferred from expectorant action
more plants for cough →detailed sources →inferred from diaphoretic action
more plants for fever →detailed sources →Carminative and aromatic bitter digestive (indigestion, bloating, flatulence)
more plants for indigestion →detailed sources →inferred from anti-inflammatory action
more plants for inflammation (general) →detailed sources →inferred from sedative action
more plants for insomnia / sleeplessness →detailed sources →inferred from neuroprotective action
more plants for memory →detailed sources →Anxiolytic / sedative (anxiety, nervous tension)
more plants for nervous tension →detailed sources →inferred from expectorant action
more plants for respiratory support →detailed sources →inferred from anti-inflammatory action
more plants for skin irritation →detailed sources →inferred from anxiolytic action
more plants for stress →detailed sources →Overactive bladder - a pilot RCT of an Angelica archangelica leaf extract reduced daytime voids and storage symptoms and improved quality of life, with near-significant benefit for nocturia
more plants for urinary support →detailed sources →Safety, Cautions & Contraindications
Contains furanocoumarins, which can cause photosensitivity; avoid excessive sun or UV exposure while using the herb medicinally.
Medicinal doses should be avoided during pregnancy and breastfeeding.
Coumarin constituents may interact with anticoagulant medicines, and furanocoumarins with photosensitising drugs; when wild-harvesting, take great care to distinguish garden angelica from poisonous Apiaceae look-alikes such as hemlock.
References & Sources
- Kaur, A. and Bhatti, R (2021) 'Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components', Phytotherapy Research. doi:10.1002/ptr.7206 Traditional / reference
https://doi.org/10.1002/ptr.7206 - Patel, D.K. and Patel, K (2023) 'Biological Potential and Pharmacological Activity of Columbianetin in Chronic Diseases', Drug Metabolism and Bioanalysis Letters. doi:10.2174/1872312815666230124154630 Traditional / reference
https://doi.org/10.2174/1872312815666230124154630 - Suenaga-Hiromori, M., Mogi, D., Kikuchi, Y., Tong, J., Kurisu, N., Aoki, Y. and others (2022) 'Comprehensive identification of terpene synthase genes and organ-dependent accumulation of terpenoid volatiles in a traditional medicinal plant Angelica archangelica L', Plant Biotechnology, 39(4), pp. 391--404. doi:10.5511/plantbiotechnology.22.1006a Traditional / reference
https://doi.org/10.5511/plantbiotechnology.22.1006a - Raafat, B.M., Gamal-Eldeen, A.M., Almehmadi, M.M., El-Daly, S.M., Faizo, N.L. and Althobaiti, F (2022) 'Angelica archangelica and Ginkgo biloba Extracts Recover Functional Blood Hemoglobin Derivatives in Rabbits Exposed to High Altitude', Current Pharmaceutical Biotechnology, 23(11), pp. 1377--1382. doi:10.2174/1389201022666211118112356 Preclinical
https://doi.org/10.2174/1389201022666211118112356 - Kaur, A. and Bhatti, R (2021) 'Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components', Phytotherapy Research, 35(11), pp. 5961--5979. doi:10.1002/ptr.7206 Preclinical
https://doi.org/10.1002/ptr.7206 - Kaur, A., Singh, N., Bhatti, M.S. and Bhatti, R (2020) 'Optimization of extraction conditions of Angelica archangelica extract and activity evaluation in experimental fibromyalgia', Journal of Food Science, 85(11), pp. 3700--3710. doi:10.1111/1750-3841.15476 Preclinical
https://doi.org/10.1111/1750-3841.15476 - Suciu, F., Mihai, D.P., Ungurianu, A., Andrei, C., Puscasu, C., Chitescu, C.L. and others (2025) 'Investigation of Anticonvulsant Potential of Morus, Angelica, Passiflora and Viola Extracts: In Vivo and In Silico Studies', International Journal of Molecular Sciences, 26(13). doi:10.3390/ijms26136426 Preclinical
https://doi.org/10.3390/ijms26136426 - Lopez-Seoane, J., Gesteiro, E., Castro-Alija, M.J., Quesada-Gonzalez, C., Perez-Ruiz, M. and Gonzalez-Gross, M (2025) 'Effects of Angelica archangelica Extract on Overactive Bladder: A Pilot Randomized Controlled Trial', Food Science & Nutrition, 13(12). doi:10.1002/fsn3.71258 Randomized trial
https://doi.org/10.1002/fsn3.71258
Generated June 22, 2026 from omniasana.bio