Plant Comparison

Feverfew vs Dandelion

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant AFeverfewTanacetum partheniumAsteraceaeFull monograph →
Plant BDandelionTaraxacum officinaleAsteraceaeFull monograph →

At a glance

Feverfew and Dandelion: both belong to the Asteraceae family; they share 3 indicated uses (arthritis / joint pain, inflammation (general), skin irritation); 1 pharmacological action in common.

FeverfewDandelion
Constituents24
Pharmacological actions116
Indicated uses717
Safety notes25
Cited sources1656
Indicated uses
Only Feverfew
FeverHeadacheMigrainePain (general)
Shared (3)
Arthritis / joint painInflammation (general)Skin irritation
Only Dandelion
Loss of appetiteBloatingCancer (anticancer research)ConstipationDetox / cleansingIndigestionInfection (general)Liver supportSwelling / fluid retentionUrinary supportUrinary tract infection (UTI)WoundsCardiovascular / heart healthImmune support
Pharmacological actions
Only Feverfew
none
Shared (1)
Anti-inflammatory
Only Dandelion
Anticancer (preclinical)AntimicrobialAntioxidantBitter digestive tonic / stomachicCholeretic / cholagogue (bile flow)Digestive aidDiureticHepatoprotective (liver support)LaxativePrebioticLipid-loweringAntiviralImmunomodulator / immune supportNeuroprotective / cognition supportAntihypertensive

Evidence face-off — shared uses

ConditionFeverfewDandelionVerdict
Arthritis / joint pain8/101/10Stronger for Feverfew
Inflammation (general)8/101/10Stronger for Feverfew
Skin irritation8/101/10Stronger for Feverfew

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Sesquiterpene lactones (parthenolide)[8, 9, 11, 12, 13]

Parthenolide is the principal active compound, to which extracts are often standardised; it is biosynthesised and stored in the glandular trichomes of the aerial parts.

Sesquiterpene lactonesSesquiterpenesParthenolide
Flavonoids and essential oil[11]

Supporting antioxidant and aromatic constituents.

Essential (volatile) oilFlavonoids
Sesquiterpene lactones[20, 50, 51]

Bitter principles (e.g. taraxacin) responsible for the characteristic bitterness and bitter-tonic action.

Sesquiterpene lactonesSesquiterpenes
Triterpenes and plant sterols[50, 52]

Including taraxasterol; contribute to anti-inflammatory and hepatoprotective signals.

Terpenes / terpenoidsPhytosterols
Phenolic acids and flavonoids[17, 21, 22, 52, 53]

Antioxidant constituents (e.g. chicoric acid, luteolin derivatives).

Phenolic acidsFlavonoidsLuteolin
Inulin[50, 53]

Fructan storage carbohydrate; prebiotic fibre concentrated in the autumn root.

PolysaccharidesInulin

Pharmacological Actions

Anti-inflammatory[3, 7, 11, 12]

Anti-inflammatory - parthenolide inhibits NF-kB and nitroglycerin-induced neuronal (Fos) activation, the proposed basis of its antimigraine action

Anti-inflammatory[14, 15, 16, 22, 25, 26, 30, 43, 44, 50, 52]
Parts: Whole plant
Anticancer (preclinical)[18, 23, 27, 28, 35, 36, 37, 38, 39, 40, 41]
Antimicrobial[32, 52]
Parts: Whole plant
Antioxidant[16, 21, 23, 28, 31, 52, 53]
Parts: Whole plant
Bitter digestive tonic / stomachic[50, 54]
Parts: Leaf
Choleretic / cholagogue (bile flow)[50, 51]

Choleretic (stimulates bile flow)

Parts: Leaf, Root
Digestive aid[50, 54]
Parts: Leaf
Diuretic[47, 50, 51, 55]

Diuretic (potassium-sparing)

Parts: Leaf
Hepatoprotective (liver support)[15, 25, 29, 42, 50, 51, 53]

Hepatic (liver) support

Parts: Root
Laxative[50, 54]
Parts: Root
Prebiotic[50, 53]

Prebiotic (inulin-rich, especially autumn root)

Parts: Root
Lipid-lowering[31, 34]
Antiviral[42]
Immunomodulator / immune support[43, 45]
Neuroprotective / cognition support[44]
Antihypertensive[46]

Traditional & Indicated Uses

Arthritis / joint pain[3, 11]Good · 8/10

Traditional use for fever and for joint pain / arthritis

Evidence: 8
Label: Arthritis / joint pain
Fever[3, 11]Good · 8/10

Traditional use for fever and for joint pain / arthritis

Evidence: 8
Label: Fever
Headache[1, 6, 11]Strong · 9/10

Headache prevention and relief

Evidence: 9
Label: Headache
Inflammation (general)[7, 11, 12]Good · 8/10

inferred from anti-inflammatory action

Evidence: 8
Label: Inflammation (general)
Migraine[1, 2, 3, 4, 5, 6, 10, 11, 12]Strong · 10/10

Migraine prophylaxis - reduces attack frequency (evidence favourable for some standardised preparations, though mixed); parthenolide is identified as the component responsible for the antimigraine effect in animal models

Evidence: 10
Label: Migraine
Pain (general)[11]Good · 7/10

Traditional use for fever and for joint pain / arthritis

Evidence: 7
Label: Pain (general)
Skin irritation[11, 12]Good · 8/10

inferred from anti-inflammatory action

Evidence: 8
Label: Skin irritation
Loss of appetite[50, 54]Traditional · 1/10

inferred from bitter-tonic action

Evidence: 1
Label: Loss of appetite
Arthritis / joint pain[50, 52]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bloating[50, 54]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Cancer (anticancer research)[18, 23, 27, 35]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Constipation[50, 54]Traditional · 1/10

inferred from laxative action

Evidence: 1
Label: Constipation
Detox / cleansing[50, 51, 53]Traditional · 1/10

inferred from hepatoprotective action

Evidence: 1
Label: Detox / cleansing
Indigestion[50, 54]Traditional · 1/10

inferred from bitter-tonic action

Evidence: 1
Label: Indigestion
Infection (general)[52]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[50, 52]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Liver support[50, 51]Traditional · 1/10

inferred from choleretic action

Evidence: 1
Label: Liver support
Skin irritation[50, 52]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Swelling / fluid retention[50, 51, 55]Moderate · 5/10

inferred from diuretic action

Evidence: 5
Label: Swelling / fluid retention
Urinary support[50, 51, 55]Moderate · 5/10

inferred from diuretic action

Evidence: 5
Label: Urinary support
Urinary tract infection (UTI)[50, 51, 55]Moderate · 5/10

inferred from diuretic action

Evidence: 5
Label: Urinary tract infection (UTI)
Wounds[52]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Cardiovascular / heart health[31, 46]Traditional · 2/10

Dandelion root and leaf lowered serum lipids and oxidative stress (preclinical).

Evidence: 2
Label: Cardiovascular / heart health
Immune support[43, 45]Traditional · 2/10

Taraxasterol modulated the inflammatory/immune response in endotoxic shock (preclinical).

Evidence: 2
Label: Immune support

Safety, Cautions & Contraindications

Safety note[11]Info

As a member of the daisy family (Asteraceae), it can cause allergic reactions in people sensitive to ragweed and related plants. Chewing fresh leaves commonly causes mouth ulcers and oral soreness.

Safety note[11]Caution

Stopping feverfew abruptly after prolonged use can cause a 'post-feverfew' rebound of headache, anxiety and muscle/joint stiffness. Avoid in pregnancy (uterine-stimulant) and breastfeeding, and use caution with anticoagulant/antiplatelet medicines.

Safety note[54, 56]Info

Allergy risk in individuals sensitive to Asteraceae (daisy family) plants such as ragweed and chamomile.

Safety note[54]Caution

Avoid medicinal use in anyone with a blocked bile duct or gallstones; use caution with gallbladder or serious liver disease.

Safety note[54, 56]Caution

May potentiate prescription diuretics; possible interactions with lithium and drugs metabolised by the liver.

Safety note[51, 54]Info

Can accumulate soil pollutants and heavy metals; harvest from clean, unpolluted sites.

Safety note[54]Caution

Use during pregnancy or breastfeeding should be guided by a qualified practitioner. Herbal use should support, not replace, conventional medical care.

External Ids

Gbif: 3118430
Wikidata: Q818481
Gbif: 5394163
Wikidata: Q131219

Botanical Description

Aromatic perennial herb (Asteraceae), 20-60 cm tall, with much-branched, downy stems. Leaves are yellow-green, bipinnately divided and strongly scented. Small, daisy-like flower heads have white ray florets and a flat yellow disc, borne in loose clusters.[13]

Height: 20-60 cm
Habit: Erect, much-branched, aromatic perennial herb
Leaves: Yellow-green, bipinnately divided, strongly scented
Flowers: Small, daisy-like, white ray florets around a flat yellow disc
Stem: Much-branched, downy
Root: Fibrous perennial rootstock
Fruit: Small ribbed achenes (typical Asteraceae)
Flowering Period: June-September

Perennial herb (Asteraceae) with a deep taproot, forming a basal rosette of deeply toothed, lance-shaped leaves - the name 'dandelion' comes from the French 'dent-de-lion', lion's tooth. Hollow flowering stalks each bear a single, bright yellow composite flower head made entirely of ray florets, followed by the familiar spherical 'clock' of parachute-tufted seeds (achenes) that disperse on the wind.[50]

Height: Low rosette; flowering stalks 5-40 cm
Habit: Deep-taprooted perennial rosette herb
Leaves: Deeply toothed, lance-shaped, in a basal rosette
Flowers: Single, bright yellow composite head of ray florets, on a hollow stalk
Stem: Hollow flowering stalk (scape), leafless
Root: Deep taproot
Fruit: Small achenes with a parachute-like pappus (the "clock")
Flowering Period: Can flower almost year-round, peaking March-October

Habitat

Native to the Balkans and Caucasus region, now naturalised across Europe, North America and elsewhere; grows on disturbed ground, walls, roadsides and waste places, and is widely cultivated.[11]

Native to Europe and Asia, now a cosmopolitan weed found on every continent except Antarctica; grows in lawns, meadows, roadsides, waste ground and disturbed soil of almost any type.[50]

Harvesting

Leaves (aerial parts) are gathered during the growing season, ideally at flowering, and dried or used fresh.[13]

Parts: Leaf (aerial parts)
Season: Growing season, ideally at flowering

Leaves are picked young in spring for the mildest flavour; the root is dug in autumn (traditionally after the first frost), when its inulin and bitter-principle content is considered optimal; flowers are picked as they open.[50, 53]

Parts: Leaf, Root, Flower
Season: Leaf in spring; root in autumn; flower as it opens

Traditional Uses

Feverfew has a long European folk tradition, its name derived from 'febrifuge' (fever-reducer), as a remedy for fevers, headaches and joint pain. Modern use and clinical research focus on migraine prevention, with parthenolide identified as the key active compound responsible for inhibiting the inflammatory pathways implicated in migraine.[11]

Dandelion is one of the most widely used bitter tonic herbs worldwide, traditionally taken as a digestive bitter and mild diuretic - the French name 'pissenlit' (wet-the-bed) reflects this - and the root specifically as a liver and gallbladder tonic. Every part is also used as food: spring greens, roasted-root coffee substitute, and flower wine.[50]

Preparations

Standardised leaf extract (capsule)[11]

Freeze-dried or standardised-parthenolide extract, the form used in most clinical trials.

Leaf infusion/salad (fresh or dried)[50]

Fresh young leaves eaten as a bitter salad green, or dried leaf infused as tea - the traditional digestive/diuretic preparation.

Root decoction[50]

Dried root simmered in water - the traditional liver-tonic preparation.

Dosage

Standardised extract[11, 12]

Clinical trials for migraine prevention have most often used standardised extracts providing around 0.2-0.6% parthenolide, taken daily; do not stop abruptly after prolonged use given a documented 'post-feverfew' rebound syndrome. Educational reference only, not a prescription; avoid in pregnancy and with anticoagulants.

Leaf/root infusion or decoction[50, 54]

Traditional guidance suggests roughly 4-10 g dried leaf, or 2-8 g dried root, per day as an infusion or decoction, divided into 2-3 doses. Educational reference only, not a prescription; avoid in bile-duct obstruction or gallstones, and harvest away from polluted ground.

References

REF-1572, REF-1573, REF-1574, REF-1575, REF-1576, REF-1577, REF-1578, REF-1579, REF-1580, REF-1581
REF-0248, REF-0320, REF-0322, REF-0323, REF-0324, REF-0325, REF-0327, REF-0330, REF-0331, REF-0334, REF-0335, REF-0336, REF-0337, REF-2387, REF-2388, REF-2389, REF-2390, REF-2391, REF-2392, REF-2393, REF-2394, REF-2395, REF-2396, REF-2945, REF-2946, REF-2947, REF-2948, REF-2949, REF-2950, REF-2951, REF-2952, REF-2953, REF-2954, REF-2955, REF-2956, REF-2957, REF-2958, REF-2959, REF-2960, REF-2961, REF-2962, REF-2963, REF-2964, REF-2965, REF-2966, REF-2967, REF-2968, REF-0070, REF-0264

Drug Class Interactions

Safety note[14]Caution
Drug Class: anticoagulants-antiplatelets
Mechanism: Feverfew and its component parthenolide inhibit platelet aggregation and serotonin release, so combining it with anticoagulant or antiplatelet drugs may increase bleeding risk.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Not documented

Pairings

Feverfew and ginger both reduce blood clotting/platelet stickiness, so taking them together may add up and raise the risk of bruising or bleeding — use caution, especially before surgery or alongside blood-thinning drugs.[14, 15, 16]

Partner Id: zingiber-officinale
Type: caution
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Not documented

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

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  2. Pittler, M.H., Vogler, B.K. and Ernst, E (2000) 'Feverfew for preventing migraine', Cochrane Database of Systematic Reviews, (3), pp. CD002286. doi:10.1002/14651858.CD002286 Meta-analysis / review
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  4. Lopresti, A.L., Smith, S.J. and Drummond, P.D (2020) 'Herbal treatments for migraine: A systematic review of randomised-controlled studies', Phytotherapy Research, 34(10), pp. 2493-2517. doi:10.1002/ptr.6701 Meta-analysis / review
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  5. Pfaffenrath, V., Diener, H.C., Fischer, M., Friede, M. and Henneicke-von Zepelin, H.H (2002) 'The efficacy and safety of Tanacetum parthenium (feverfew) in migraine prophylaxis - a double-blind, multicentre, randomized placebo-controlled dose-response study', Cephalalgia, 22(7), pp. 523-532. doi:10.1046/j.1468-2982.2002.00396.x Randomized trial
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  10. Studzinska-Sroka, E., Znajdek-Awizen, P. and Gawron-Gzella, A (2013) 'Studies on the antimigraine action of Feverfew (Tanacetum parthenium (L.) Sch. Bip.)', Wiadomosci Lekarskie, 66(2 Pt 2), pp. 195-199. Meta-analysis / review
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  11. Wider, B., Pittler, M.H. and Ernst, E (2015) 'Feverfew for preventing migraine', Cochrane Database of Systematic Reviews. doi:10.1002/14651858.CD002286.pub3 Meta-analysis / review
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  12. Tassorelli, C. and Greco, R. and Morazzoni, P. and Riva, A. and Sandrini, G. and Nappi, G (2005) 'Parthenolide is the component of Tanacetum parthenium that inhibits nitroglycerin-induced Fos activation: studies in an animal model of migraine', Cephalalgia, 25(8), pp. 612--621. doi:10.1111/j.1468-2982.2005.00915.x Randomized trial
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  13. Majdi, M. and Liu, Q. and Karimzadeh, G. and Malboobi, M.A. and Beekwilder, J. and Cankar, K. and de Vos, R. and Todorovic, S. and Simonovic, A. and Bouwmeester, H (2011) 'Biosynthesis and localization of parthenolide in glandular trichomes of feverfew (Tanacetum parthenium L. Schulz Bip.)', Phytochemistry, pp. 1739--1750. doi:10.1016/j.phytochem.2011.04.021 Preclinical
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  14. Groenewegen, W.A. and Heptinstall, S (1990) 'A comparison of the effects of an extract of feverfew and parthenolide, a component of feverfew, on human platelet activity in-vitro', Journal of Pharmacy and Pharmacology, 42(8), pp. 553-557. doi:10.1111/j.2042-7158.1990.tb07057.x Preclinical
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  15. Ang-Lee, M.K., Moss, J. and Yuan, C.S (2001) 'Herbal medicines and perioperative care', JAMA, 286(2), pp. 208-216. doi:10.1001/jama.286.2.208 Meta-analysis / review
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  16. Jiang, X., Williams, K.M., Liauw, W.S., Ammit, A.J., Roufogalis, B.D., Duke, C.C., Day, R.O. and McLachlan, A.J (2005) 'Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects', British Journal of Clinical Pharmacology, 59(4), pp. 425-432. doi:10.1111/j.1365-2125.2005.02322.x Randomized trial
    https://doi.org/10.1111/j.1365-2125.2005.02322.x
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.