Plant Comparison

Greater Plantain vs Breckland Thyme

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
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Plant AGreater PlantainPlantago majorPlantaginaceaeFull monograph →
Plant BBreckland ThymeThymus serpyllumLamiaceaeFull monograph →

At a glance

Greater Plantain and Breckland Thyme: they share 7 indicated uses (arthritis / joint pain, infection (general), inflammation (general), …); 4 pharmacological actions in common.

Greater PlantainBreckland Thyme
Constituents53
Pharmacological actions135
Indicated uses159
Safety notes52
Cited sources5414
Indicated uses
Only Greater Plantain
BronchitisBruisingConstipationCoughDiarrhoeaSore throatImmune supportCardiovascular / heart health
Shared (7)
Arthritis / joint painInfection (general)Inflammation (general)Respiratory supportSkin irritationWoundsCancer (anticancer research)
Only Breckland Thyme
Acid refluxIndigestion
Pharmacological actions
Only Greater Plantain
AstringentDemulcent (soothing mucilage)ExpectorantLaxativeVulnerary (wound healing)Immunomodulator / immune supportAntiviralAnalgesic (pain relief)Antifungal
Shared (4)
Anti-inflammatoryAntimicrobialAntioxidantAnticancer (preclinical)
Only Breckland Thyme
Gastroprotective

Evidence face-off — shared uses

ConditionGreater PlantainBreckland ThymeVerdict
Arthritis / joint pain1/101/10Comparable evidence
Infection (general)1/101/10Comparable evidence
Inflammation (general)1/101/10Comparable evidence
Respiratory support1/101/10Comparable evidence
Skin irritation1/101/10Comparable evidence
Wounds2/101/10Comparable evidence
Cancer (anticancer research)2/102/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Iridoid glycosides (aucubin, catalpol)[1, 36]

Characteristic iridoids of Plantago major.

Iridoid glycosidesGlycosides
Caffeic acid esters (plantamajoside, acteoside/verbascoside)[1, 36]

Polyphenolic esters contributing to antioxidant and anti-inflammatory activity.

Caffeic acidVerbascoside (acteoside)
Flavonoids (baicalein, luteolin, hispidulin)[1]

Flavonoid constituents of the leaf.

FlavonoidsLuteolin
Allantoin[36]

Cell-proliferative compound supporting wound healing.

Allantoin
Mucilage and triterpenes (ursolic and oleanolic acid)[1, 36]

Demulcent mucilage plus anti-inflammatory triterpenes.

Terpenes / terpenoidsMucilage
Essential oil (thymol, carvacrol, p-cymene)[2]

The volatile oil, dominated by thymol and carvacrol, gives most of the antimicrobial and antioxidant activity.

Essential (volatile) oilThymolCarvacrolTerpenes / terpenoids
Phenolic acids and flavonoids (rosmarinic acid, luteolin)[3]

Contribute additional antioxidant activity.

Rosmarinic acidPhenolic acidsFlavonoidsLuteolin
Triterpenes (ursolic acid, oleanolic acid)[1]

Minor constituents studied for anti-inflammatory activity.

Pharmacological Actions

Anti-inflammatory[7, 8, 29, 30, 31, 39, 40, 41]
Antimicrobial[1, 9, 32, 35]
Antioxidant[1, 11, 12, 23, 24, 34, 39, 40, 41]
Astringent[37, 38]

Astringent (diarrhoea)

Demulcent (soothing mucilage)[6, 13, 37, 38]

Demulcent / expectorant (coughs, catarrh, irritated airways)

Expectorant[2, 10, 37, 38, 39, 40, 41]

Demulcent / expectorant (coughs, catarrh, irritated airways)

Laxative[2, 13, 38]

Bulk laxative (mucilaginous seeds)

Vulnerary (wound healing)[3, 4, 5, 25, 26, 27, 28, 36, 38, 39, 40, 41, 42]

Vulnerary (wound healing) - fresh leaf poultice

Immunomodulator / immune support[16, 17, 18, 19, 20]
Antiviral[16, 33]
Anticancer (preclinical)[16, 21, 22]
Analgesic (pain relief)[30]
Antifungal[35]
Anti-inflammatory[1, 6, 11, 12, 13]
Anticancer (preclinical)[9]
Antimicrobial[1, 4, 5, 6, 11, 12, 13]
Antioxidant[1, 2, 3, 4, 6, 11, 12, 13]
Gastroprotective[11, 12, 13]

Traditional & Indicated Uses

Arthritis / joint pain[39, 40, 41]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bronchitis[37, 38, 39, 40, 41]Traditional · 1/10

inferred from expectorant action

Evidence: 1
Label: Bronchitis
Bruising[36, 38, 39, 40, 41, 42]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Constipation[38]Traditional · 1/10

inferred from laxative action

Evidence: 1
Label: Constipation
Cough[37, 38]Traditional · 1/10

Demulcent / expectorant (coughs, catarrh, irritated airways)

Evidence: 1
Label: Cough
Diarrhoea[37, 38]Traditional · 1/10

Astringent (diarrhoea)

Evidence: 1
Label: Diarrhoea
Infection (general)[1]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[39, 40, 41]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Respiratory support[37, 38, 39, 40, 41]Traditional · 1/10

inferred from expectorant action

Evidence: 1
Label: Respiratory support
Skin irritation[39, 40, 41]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Sore throat[37, 38]Traditional · 1/10

inferred from demulcent action

Evidence: 1
Label: Sore throat
Wounds[25, 36, 38, 39, 40, 41, 42]Traditional · 2/10

inferred from vulnerary action

Evidence: 2
Label: Wounds
Immune support[16]Traditional · 2/10

P. major extract showed immunomodulatory, antiviral and cytotoxic effects in vitro.

Evidence: 2
Label: Immune support
Cancer (anticancer research)[21]Traditional · 2/10

P. major extracts/compounds inhibited proliferation of cancer cell lines (preclinical).

Evidence: 2
Label: Cancer (anticancer research)
Cardiovascular / heart health[23, 24]Traditional · 2/10

Plantamajoside attenuated cardiac fibrosis via AGEs/RAGE inhibition (preclinical).

Evidence: 2
Label: Cardiovascular / heart health
Acid reflux[11, 12, 13]Traditional · 1/10

inferred from gastroprotective action

Evidence: 1
Label: Acid reflux
Arthritis / joint pain[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Cancer (anticancer research)[9]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Indigestion[11, 12, 13]Traditional · 1/10

inferred from gastroprotective action

Evidence: 1
Label: Indigestion
Infection (general)[11, 12, 13]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Respiratory support[11, 12, 13]Traditional · 1/10
Evidence: 1
Label: Respiratory support
Skin irritation[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[11, 12, 13]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds

Safety, Cautions & Contraindications

Safety note[39, 40, 41]Caution

Extremely safe; one of the most widely used edible and medicinal plants in the world. Psyllium seeds (closely related) are well-studied as a bulk laxative but should always be taken with adequate water. Allergic reactions are rare but possible. No significant drug interactions documented at normal doses.

Safety note[39, 40, 41, 43]Info

Duke (2002) rates plantain as ++ and notes anti-inflammatory, antitussive, antiatherosclerotic, and COX-2-inhibitory activities at the experimental level (score 1). The seeds (psyllium) of related species have clinical evidence for cholesterol reduction and as bulk laxatives, though entries here apply to the leaf. Dose: leaf as tea or poultice for wounds, sore throat, and bronchial conditions. Duke notes the plant is generally safe with anti-inflammatory topical use well-supported in traditional practice. Commission E approved plantain (ribwort species) for catarrh and wound healing (Duke, 2002).

Safety note[36, 38]Info

Generally regarded as safe as food and in customary medicinal use; allergic reactions are uncommon, though the abundant wind-borne pollen can aggravate hay fever in sensitive people.

Safety note[36, 44]Info

Correct identification is essential and material should be gathered away from roadsides, sprayed lawns and other contaminated ground; deep or infected wounds warrant proper medical care.

Safety note[45, 46, 47, 48, 49, 50, 51, 52, 53, 54]Info

Additional omniasana.bio sources cited for Plantago major (identification, distribution, foraging, traditional use and supporting evidence; see bibliography).

Safety note[11, 12, 13]Caution

Generally safe at culinary doses. Essential oil is highly concentrated and must be diluted before topical use; undiluted application can cause skin sensitisation. Not recommended internally during pregnancy (uterine stimulant effects possible). Phenol-rich thyme preparations should be avoided long-term in high doses. May potentiate anticoagulant medications.

Safety note[11, 12, 13, 14]Info

Duke (2002) rates Thymus vulgaris (garden thyme, closely related to breckland thyme) as +++ with clinical evidence (score 2) for antibacterial, bronchospasmolytic, and antispasmodic activities, consistent with Commission E and WHO approvals for bronchitis and upper respiratory catarrh. The primary active constituent is thymol, with carvacrol as a secondary compound. Dose: 1–2 g dried herb as tea three times daily. The plant demonstrates COX-2 inhibitory activity and calcium antagonism, which may explain its antispasmodic effects (Duke, 2002).

External Ids

Gbif: 3189767
Wikidata: Q157154
Gbif: 6409622
Wikidata: Q147251

Botanical Description

Low, rosette-forming perennial herb (Plantaginaceae) with broad, oval to rounded leaves marked by 5-9 prominent parallel ribs, borne on long, channelled petioles. Slender, leafless flowering spikes rise from the rosette bearing tiny, densely packed greenish flowers, followed by small seed capsules.[36]

Height: Low rosette; flowering spikes 10-40 cm
Habit: Low rosette-forming perennial herb
Leaves: Broad, oval to rounded, 5-9-ribbed, long-petioled
Flowers: Tiny, densely packed, greenish, in slender spikes
Stem: Slender, leafless flowering spike
Root: Fibrous perennial rootstock
Fruit: Small seed capsule
Flowering Period: June-September

Low, mat-forming, aromatic perennial subshrub with tiny, oval, strongly aromatic leaves on trailing, wiry, hairy stems that root as they spread. Small, pinkish-purple, two-lipped flowers are borne in dense whorled clusters at the stem tips.

Height: 2-10 cm (mat-forming, trailing)
Habit: Low, mat-forming, aromatic perennial subshrub
Leaves: Tiny, oval, strongly aromatic
Flowers: Small, pinkish-purple, two-lipped, in dense whorled terminal clusters
Stem: Trailing, wiry, hairy, rooting as it spreads
Root: Fine, fibrous roots along the creeping stem
Fruit: Small nutlet
Flowering Period: May-September

Habitat

Native to Europe and temperate Asia and now one of the most widespread naturalised weeds worldwide (the name 'waybread', or historically 'white man's foot', reflects its spread along paths and trails); thrives on compacted, disturbed ground such as paths, lawns and roadsides.[36]

Grows on dry, sunny heath, grassland, rocky ground and sandy soils; native to Europe and widely distributed across the northern temperate zone.

Harvesting

Leaves are gathered fresh throughout the growing season, especially for poultice use; seed is collected in autumn once ripe.[36]

Parts: Leaf, Seed
Season: Leaf throughout the growing season; seed in autumn

The flowering aerial parts (flower and leaf) are cut at the start of flowering in summer and dried in a warm, shaded, airy place.

Parts: Flower, Leaf
Season: Summer, at start of flowering

Traditional Uses

Greater plantain is one of the most widely used wound herbs across world folk-medicine traditions, applied fresh as a poultice to cuts, stings and insect bites, and taken as a tea for cough, digestive upset and mild diarrhoea. Modern reviews confirm broad anti-inflammatory, antimicrobial, antioxidant and wound-healing activity supporting these traditional uses.[1, 36]

Wild thyme has a long European folk tradition, closely paralleling its relative garden thyme, as an antimicrobial and expectorant remedy for coughs and respiratory infections, a digestive/gastroprotective herb, and a topical antiseptic.[11, 12, 13]

Preparations

Fresh leaf poultice[36]

Crushed or chewed fresh leaf applied directly to wounds, stings and insect bites - the classic traditional first-aid use.

Infusion (tea)[37, 38]

Dried leaf steeped in hot water for cough, digestive complaints and mild diarrhoea.

Seed (bulk fibre)[38]

The mucilaginous seed, related to psyllium, used traditionally as a mild bulk laxative.

Infusion[12]

Dried flowering herb infused in hot water as a traditional respiratory and digestive tea.

Dosage

Leaf tea / poultice[39, 40, 41]

Duke (2002): leaf taken as a tea, or used fresh as a poultice, for wounds, sore throat and bronchial conditions. Educational reference only, not a prescription.

Not documented

References

REF-0354, REF-1758, REF-1759, REF-1760, REF-1761, REF-1762, REF-1763, REF-1764, REF-1765, REF-1766, REF-1767, REF-1768, REF-1769, REF-2993, REF-2994, REF-2995, REF-2996, REF-2997, REF-2998, REF-2999, REF-3000, REF-3001, REF-3002, REF-3003, REF-3004, REF-3005, REF-3006, REF-3007, REF-3008, REF-3009, REF-3010, REF-3011, REF-3012, REF-3013, REF-3014
REF-1094, REF-1095, REF-1096, REF-1097, REF-1098, REF-1099, REF-1100, REF-1101, REF-1102, REF-1103

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Adom, M.B., Taher, M., Mutalabisin, M.F., Amri, M.S., Abdul Kudos, M.B., Wan Sulaiman, M.W.A., Sengupta, P. and Susanti, D (2017) 'Chemical constituents and medical benefits of Plantago major', pp. 348--360. doi:10.1016/j.biopha.2017.09.152 Traditional / reference
    https://doi.org/10.1016/j.biopha.2017.09.152
  2. Najafian, Y., Hamedi, S.S., Farshchi, M.K. and Feyzabadi, Z (2018) 'Plantago major in Traditional Persian Medicine and modern phytotherapy: a narrative review', Electronic Physician, 10(2), pp. 6390-6399. doi:10.19082/6390 Meta-analysis / review
    https://doi.org/10.19082/6390
  3. Cardoso, F.C.I., Breder, J.C., Apolinario, P.P., Oliveira, H.C., Saidel, M.G.B., Dini, A.P., Oliveira-Kumakura, A.R. and Lima, M.H.M (2021) 'The Effect of Plantago major on Wound Healing in Preclinical Studies: A Systematic Review', Wound Management & Prevention, 67(1), pp. 27-34. doi:10.25270/wmp.2021.1.2734 Meta-analysis / review
    https://doi.org/10.25270/wmp.2021.1.2734
  4. Ghanadian, M., Soltani, R., Homayouni, A., Khorvash, F., Jouabadi, S.M. and Abdollahzadeh, M (2022) 'The Effect of Plantago major Hydroalcoholic Extract on the Healing of Diabetic Foot and Pressure Ulcers: A Randomized Open-Label Controlled Clinical Trial', The International Journal of Lower Extremity Wounds, 23(3), pp. 475-481. doi:10.1177/15347346211070723 Randomized trial
    https://doi.org/10.1177/15347346211070723
  5. Ghiasian, M., Niroomandi, Z., Dastan, D., Poorolajal, J., Zare, F. and Ataei, S (2021) 'Clinical and phytochemical studies of Plantago major in pressure ulcer treatment: A randomized controlled trial', Complementary Therapies in Clinical Practice, 43, pp. 101325. doi:10.1016/j.ctcp.2021.101325 Randomized trial
    https://doi.org/10.1016/j.ctcp.2021.101325
  6. Cabrera-Jaime, S., Martinez, C., Ferro-Garcia, T., Giner-Boya, P., Icart-Isern, T., Estrada-Masllorens, J.M. and Fernandez-Ortega, P (2017) 'Efficacy of Plantago major, chlorhexidine 0.12% and sodium bicarbonate 5% solution in the treatment of oral mucositis in cancer patients with solid tumour: A feasibility randomised triple-blind phase III clinical trial', European Journal of Oncology Nursing, 32, pp. 40-47. doi:10.1016/j.ejon.2017.11.006 Randomized trial
    https://doi.org/10.1016/j.ejon.2017.11.006
  7. Zubair, M., Widen, C., Renvert, S. and Rumpunen, K (2018) 'Water and ethanol extracts of Plantago major leaves show anti-inflammatory activity on oral epithelial cells', Journal of Traditional and Complementary Medicine, 9(3), pp. 169-171. doi:10.1016/j.jtcme.2017.09.002 Preclinical
    https://doi.org/10.1016/j.jtcme.2017.09.002
  8. Turel, I., Ozbek, H., Erten, R., Oner, A.C., Cengiz, N. and Yilmaz, O (2009) 'Hepatoprotective and anti-inflammatory activities of Plantago major L', Indian Journal of Pharmacology, 41(3), pp. 120-124. doi:10.4103/0253-7613.55211 Preclinical
    https://doi.org/10.4103/0253-7613.55211
  9. Turki Monawer, A. and Mohammed Abdulkahar Mammani, I (2023) 'Antibacterial activity of ethanolic extracts of Plantago major leaves against Pseudomonas aeruginosa from burn infections', Journal of Infection in Developing Countries, 17(2), pp. 276-280. doi:10.3855/jidc.17576 Preclinical
    https://doi.org/10.3855/jidc.17576
  10. Boskabadi, J., Saadat, S. and Boskabady, M.H (2020) 'The Relaxant Effect of Plantago Major on Rat Tracheal Smooth Muscles and Its Possible Mechanisms', Iranian Journal of Allergy, Asthma and Immunology, 19(4), pp. 386-396. doi:10.18502/ijaai.v19i4.4113 Preclinical
    https://doi.org/10.18502/ijaai.v19i4.4113
  11. Parhizgar, S., Hosseinian, S., Soukhtanloo, M., Bideskan, A.E., Hadjzadeh, M., Shahraki, S., Noshahr, Z.S., Heravi, N.E., Haghshenas, M. and Rad, A.K (2018) 'Plantago major protects against cisplatin-induced renal dysfunction and tissue damage in rats', Saudi Journal of Kidney Diseases and Transplantation, 29(5), pp. 1057-1064. doi:10.4103/1319-2442.243960 Preclinical
    https://doi.org/10.4103/1319-2442.243960
  12. Naji Ebrahimi Yazd, Z., Shahraki, S., Hosseinian, S., Shafei, M.N., Bideskan, A.E., Mohebbati, R., Heravi, N.E., Mahzari, S. and Rad, A.K (2019) 'Renoprotective Effect of Plantago major Against Proteinuria and Apoptosis Induced by Adriamycin in Rat', Journal of Pharmacopuncture, 22(1), pp. 35-40. doi:10.3831/KPI.2019.22.004 Preclinical
    https://doi.org/10.3831/KPI.2019.22.004
  13. Alizadeh Behbahani, B., Tabatabaei Yazdi, F., Shahidi, F., Hesarinejad, M.A., Mortazavi, S.A. and Mohebbi, M (2016) 'Plantago major seed mucilage: Optimization of extraction and some physicochemical and rheological aspects', Carbohydrate Polymers, 155, pp. 68-77. doi:10.1016/j.carbpol.2016.08.051 Preclinical
    https://doi.org/10.1016/j.carbpol.2016.08.051
  14. Majeed, A. and Zulfiqar, Z. and Fatima, Z. and Fatima, S. and Muhammad, G. and Wajid, M. and Khan, R.R.M. and Mushtaq, M. and Ashraf, A (2026) 'Phytochemical profile and biological activities of Plantago major L.: A comprehensive review', Asian Pacific Journal of Tropical Biomedicine. doi:10.4103/apjtb.apjtb_644_25 Meta-analysis / review
    https://doi.org/10.4103/apjtb.apjtb_644_25
  15. Akram, M. and Hamid, A. and Khalil, A. and Ghaffar, A. and Tayyaba, N. and Saeed, A. and Ali, M. and Naveed, A (2014) 'Review on Medicinal Uses, Pharmacological, Phytochemistry and Immunomodulatory Activity of Plants', International Journal of Immunopathology and Pharmacology. doi:10.1177/039463201402700301 Meta-analysis / review
    https://doi.org/10.1177/039463201402700301
  16. Chiang, L. and Chiang, W.C. and Chang, M. and Lin, C (2003) 'In Vitro Cytotoxic, Antiviral and Immunomodulatory Effects of Plantago major and Plantago asiatica', The American Journal of Chinese Medicine. doi:10.1142/s0192415x03000874 Preclinical
    https://doi.org/10.1142/s0192415x03000874
  17. Gomez‐Flores, R. and Calderón, C.L. and Scheibel, L.W. and Tamez‐Guerra, P. and Rodrı́guez-Padilla, C. and Támez-Guerra, R. and Wéber, R (2000) 'Immunoenhancing properties ofPlantago major leaf extract', Phytotherapy Research. doi:10.1002/1099-1573(200012)14:8<617::aid-ptr674>3.0.co;2-n Preclinical
    https://doi.org/10.1002/1099-1573(200012)14:8<617::aid-ptr674>3.0.co;2-n
  18. Samuelsen, A.B. and Paulsen, B.S. and Wold, J.K. and Otsuka, H. and Yamada, H. and Espevik, T (1995) 'Isolation and partial characterization of biologically active polysaccharides from Plantago major L', Phytotherapy Research. doi:10.1002/ptr.2650090312 Preclinical
    https://doi.org/10.1002/ptr.2650090312
  19. Reina, E. and Al‐Shibani, N. and Allam, E. and Gregson, K.S. and Kowolik, M.J. and Windsor, L.J (2013) 'The Effects of Plantago major on the Activation of the Neutrophil Respiratory Burst', Journal of Traditional and Complementary Medicine. doi:10.4103/2225-4110.119706 Preclinical
    https://doi.org/10.4103/2225-4110.119706
  20. Lukova, P. and Karcheva‐Bahchevanska, D. and Bivolarski, V. and Mladenov, R. and Iliev, I. and Nikolova, M (2017) 'Enzymatic Hydrolysis of Water Extractable Polysaccharides from Leaves of Plantago major L', Folia Medica. doi:10.1515/folmed-2017-0023 Preclinical
    https://doi.org/10.1515/folmed-2017-0023
  21. Kartini, K. and Piyaviriyakul, S. and Thongpraditchote, S. and Siripong, P. and Vallisuta, O (2017) 'Effects of Plantago major extracts and its chemical compounds on proliferation of cancer cells and cytokines production of lipopolysaccharide-activated THP-1 macrophages', Pharmacognosy Magazine. doi:10.4103/pm.pm_406_16 Preclinical
    https://doi.org/10.4103/pm.pm_406_16
  22. Zuo, X. and Li, L. and Sun, L (2020) 'Plantamajoside inhibits hypoxia-induced migration and invasion of human cervical cancer cells through the NF-κB and PI3K/akt pathways', Journal of Receptors and Signal Transduction. doi:10.1080/10799893.2020.1808679 Preclinical
    https://doi.org/10.1080/10799893.2020.1808679
  23. Zhang, L. and Guo, Y. and Liu, J. and Wang, L. and Wang, L. and Wu, H. and Wang, T. and Deng, B. and Wang, J. and Lu, L. and Chen, Z. and He, J. and Liang, B. and Li, H. and Huang, Y (2022) 'Plantamajoside attenuates cardiac fibrosis via inhibiting AGEs activated‐RAGE/autophagy/EndMT pathway', Phytotherapy Research. doi:10.1002/ptr.7663 Preclinical
    https://doi.org/10.1002/ptr.7663
  24. Zeng, G. and An, H. and Fang, D. and Wang, W. and Han, Y. and Lian, C (2020) 'Plantamajoside protects H9c2 cells against hypoxia/reoxygenation-induced injury through regulating the akt/Nrf2/HO-1 and NF-κB signaling pathways', Journal of Receptors and Signal Transduction. doi:10.1080/10799893.2020.1859534 Preclinical
    https://doi.org/10.1080/10799893.2020.1859534
  25. Amini, M. and Kherad, M. and Mehrabani, D. and Azarpira, N. and Panjehshahin, M.R. and Tanideh, N (2010) 'Effect ofPlantago majoron Burn Wound Healing in Rat', Journal of Applied Animal Research. doi:10.1080/09712119.2010.9707093 Preclinical
    https://doi.org/10.1080/09712119.2010.9707093
  26. Zubaır, M. and Nybom, H. and Lindholm, C. and Brandner, J.M. and Rumpunen, K (2015) 'Promotion of wound healing byPlantago majorL. leaf extracts –ex-vivoexperiments confirm experiences from traditional medicine', Natural Product Research. doi:10.1080/14786419.2015.1034714 Preclinical
    https://doi.org/10.1080/14786419.2015.1034714
  27. Rad, N. and Shafie, F. and Chaghervand, M.M. and Kashfi, S. and Rashidipour, M. and Chehelcheraghi, F. and Mozaffarpur, S.A. and Rasoulian, B (2018) 'The Wound Healing Effect of Plantago Major Leaf Extract in a Rat Model: An Experimental Confirmation of a Traditional Belief in Persian Medicine', DOAJ (DOAJ: Directory of Open Access Journals). doi:10.22087/hmj.v3i1.702 Preclinical
    https://doi.org/10.22087/hmj.v3i1.702
  28. Cardoso, F.D.C.I. and Apolinário, P.P. and Breder, J.D.S.C. and Paranhos, T. and Oliveira, H.C. and Polidoro, A.D. and Oliveira, A.R.D.S. and Lima, M.H.M (2019) 'A protocol for systematic review of Plantago major L. effectiveness in accelerating wound-healing in animal models', Systematic Reviews. doi:10.1186/s13643-019-1255-6 Meta-analysis / review
    https://doi.org/10.1186/s13643-019-1255-6
  29. Ringbom, T. and Segura, L. and Noreen, Y. and Perera, P. and Bohlin, L (1998) 'Ursolic Acid fromPlantagomajor, a Selective Inhibitor of Cyclooxygenase-2 Catalyzed Prostaglandin Biosynthesis', Journal of Natural Products. doi:10.1021/np980088i Preclinical
    https://doi.org/10.1021/np980088i
  30. Guillén, M.E.N. and Emim, J.A.D.S. and Souccar, C. and Lapa, A.J (1997) 'Analgesic and Anti-inflammatory Activities of the Aqueous Extract of Plantago major L', International Journal of Pharmacognosy. doi:10.1076/phbi.35.2.99.13288 Preclinical
    https://doi.org/10.1076/phbi.35.2.99.13288
  31. Atibayeva, А.E. and Тыныкулов, М (2024) 'ANTI-INFLAMMATORY ACTIVITY OF PLANTAGO MAJOR LEAF EXTRACTS IN VITRO ON EPITHELIAL CELLS OF THE ORAL CAVITY', Vestnik of M Kozybayev North Kazakhstan University. doi:10.54596/2958-0048-2024-2-48-53 Preclinical
    https://doi.org/10.54596/2958-0048-2024-2-48-53
  32. Zhakipbekov, K. and Turgumbayeva, A. and Issayeva, R. and Kipchakbayeva, A. and Kadyrbayeva, G. and Tleubayeva, M.I. and Akhayeva, T. and Тастамбек, К. and Sainova, G.A. and Serikbayeva, E. and Tolenova, K. and Махатова, Б. and Anarbayeva, R. and Shimirova, Z. and Tileuberdi, Y (2023) 'Antimicrobial and Other Biomedical Properties of Extracts from Plantago major, Plantaginaceae', Pharmaceuticals. doi:10.3390/ph16081092 Preclinical
    https://doi.org/10.3390/ph16081092
  33. Povnitsa, O. and Bilyavska, L. and Pankivska, Y. and Likhanov, A. and Dorovskyh, A. and Лысенко, В.С. and Lokshin, M.M. and Zahorodnia, S (2021) 'In vitro Antiviral Activity of Leaf Extracts Plantago major, Plantago lanceolata, Rubus idaeus', Mikrobiolohichnyi Zhurnal. doi:10.15407/microbiolj84.01.044 Preclinical
    https://doi.org/10.15407/microbiolj84.01.044
  34. Han, A.Y. and Nam, M. and Lee, K (2016) 'Plantamajoside Inhibits UVB and Advanced Glycation End Products‐Induced MMP‐1 Expression by Suppressing the MAPK and NF‐κB Pathways in HaCaT Cells', Photochemistry and Photobiology. doi:10.1111/php.12615 Preclinical
    https://doi.org/10.1111/php.12615
  35. Shirley, K.P. and Windsor, L.J. and Eckert, G.J. and Gregory, R.L (2015) 'In Vitro Effects of Plantago Major Extract, Aucubin, and Baicalein on Candida albicans Biofilm Formation, Metabolic Activity, and Cell Surface Hydrophobicity', Journal of Prosthodontics. doi:10.1111/jopr.12411 Preclinical
    https://doi.org/10.1111/jopr.12411
  36. Samuelsen, A.B (2000) 'The traditional uses, chemical constituents and biological activities of Plantago major L. A review', 8741(00), pp. 1--21. doi:10.1016/s0378-8741(00)00212-9 Traditional / reference
    https://doi.org/10.1016/s0378-8741(00)00212-9
  37. Grieve, M (1931). Available at: https://botanical.com/botanical/mgmh/p/planta14.html Traditional / reference
    https://botanical.com/botanical/mgmh/p/planta14.html
  38. Herbal Reality (n.d.) 'Plantain (Plantago major): Benefits, Safety, Uses'. Available at: https://www.herbalreality.com/herb/plantain/ Traditional / reference
    https://www.herbalreality.com/herb/plantain/
  39. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
    https://powo.science.kew.org
  40. Samuelsen, A.B (2000) 'The traditional uses, chemical constituents and biological activities of Plantago major L.: a review', pp. 1--21. Traditional / reference
    https://scholar.google.com/scholar?q=The%20traditional%20uses%2C%20chemical%20constituents%20and%20biological%20activities%20of%20Plantago%20major%20L.%3A%20a%20review
  41. World Health Organization (2002) 'WHO Monographs on Selected Medicinal Plants'. Traditional / reference
    https://scholar.google.com/scholar?q=WHO%20Monographs%20on%20Selected%20Medicinal%20Plants
  42. Zubair, M., Ekholm, A., Nybom, H., Renvert, S., Widen, C. and Rumpunen, K (2012) 'Effects of Plantago major L. leaf extracts on oral epithelial cells in a scratch assay', 141(3), pp. 825--830. doi:10.1016/j.jep.2012.03.016 Traditional / reference
    https://doi.org/10.1016/j.jep.2012.03.016
  43. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  44. The Herbal Medic (n.d.) 'Plantain (Plantago lanceolata) - Wound Healing & Respiratory Support Herb'. Available at: https://theherbalmedic.co.uk/plantain-plantago-lanceolate Traditional / reference
    https://theherbalmedic.co.uk/plantain-plantago-lanceolate
  45. A Wandering Botanist (2013) 'Plant Story - Plantains (Plantago), Tracking Your Footsteps All Over the World'. Available at: http://khkeeler.blogspot.com/2013/11/plant-story-plantains-plantago-tracking.html Traditional / reference
    http://khkeeler.blogspot.com/2013/11/plant-story-plantains-plantago-tracking.html
  46. Edible Wild Food (n.d.) 'Broadleaf Plantain (Plantago major)'. Available at: https://www.ediblewildfood.com/broadleaf-plantain.aspx Traditional / reference
    https://www.ediblewildfood.com/broadleaf-plantain.aspx
  47. Florida School of Holistic Living (n.d.). Available at: https://www.holisticlivingschool.org/2020/02/25/march-plantain/ Traditional / reference
    https://www.holisticlivingschool.org/2020/02/25/march-plantain/
  48. Living Plant Wisdom (n.d.) 'Living Plant Wisdom Profile: Plantain (Plantago major)'. Available at: https://holisticfarming.substack.com/p/living-plant-wisdom-profile-plantain Traditional / reference
    https://holisticfarming.substack.com/p/living-plant-wisdom-profile-plantain
  49. Nine Herbs Charm (n.d.). Available at: https://en.wikipedia.org/wiki/Nine_Herbs_Charm Traditional / reference
    https://en.wikipedia.org/wiki/Nine_Herbs_Charm
  50. North Carolina Extension (n.d.) 'Plantago major'. Available at: https://plants.ces.ncsu.edu/plants/plantago-major/ Traditional / reference
    https://plants.ces.ncsu.edu/plants/plantago-major/
  51. Royal Botanic Gardens, Kew (n.d.) 'Plantago major L'. Available at: https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:677229-1 Traditional / reference
    https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:677229-1
  52. Royal Horticultural Society (n.d.) 'Plantago major (common plantain)'. Available at: https://www.rhs.org.uk/plants/42126/plantago-major/details Traditional / reference
    https://www.rhs.org.uk/plants/42126/plantago-major/details
  53. The Wildlife Trusts (n.d.) 'Greater plantain'. Available at: https://www.wildlifetrusts.org/wildlife-explorer/wildflowers/greater-plantain Traditional / reference
    https://www.wildlifetrusts.org/wildlife-explorer/wildflowers/greater-plantain
  54. Zubair, M (2012). Available at: https://research.slu.se/en/publications/genetic-variation-biochemical-contents-and-wound-healing-activity/ Traditional / reference
    https://research.slu.se/en/publications/genetic-variation-biochemical-contents-and-wound-healing-activity/
  1. Jalil, B., Pischel, I., Feistel, B., Suarez, C. and others (2024) 'Wild thyme (Thymus serpyllum L.): a review of the current evidence of nutritional and preventive health benefits', Frontiers in Nutrition, 11, pp. 1380962. doi:10.3389/fnut.2024.1380962 Meta-analysis / review
    https://doi.org/10.3389/fnut.2024.1380962
  2. Sonmezdag, A.S., Kelebek, H. and Selli, S (2016) 'Characterization of aroma-active and phenolic profiles of wild thyme (Thymus serpyllum) by GC-MS-Olfactometry and LC-ESI-MS/MS', Journal of Food Science and Technology, 53(4), pp. 1957-1965. doi:10.1007/s13197-015-2144-1 Preclinical
    https://doi.org/10.1007/s13197-015-2144-1
  3. Pavlic, B., Mrkonjic, Z., Teslic, N., Kljakic, A.C. and others (2022) 'Natural Deep Eutectic Solvent (NADES) Extraction Improves Polyphenol Yield and Antioxidant Activity of Wild Thyme (Thymus serpyllum L.) Extracts', Molecules, 27(5), pp. 1508. doi:10.3390/molecules27051508 Preclinical
    https://doi.org/10.3390/molecules27051508
  4. Mrkonjic, Z., Kaplan, M., Milosevic, S., Bozovic, D. and others (2024) 'Green Extraction Approach for Isolation of Bioactive Compounds in Wild Thyme (Thymus serpyllum L.) Herbal Dust-Chemical Profile, Antioxidant and Antimicrobial Activity and Comparison with Conventional Techniques', Plants, 13(6), pp. 897. doi:10.3390/plants13060897 Preclinical
    https://doi.org/10.3390/plants13060897
  5. Sokolic-Mihalak, D., Frece, J., Slavica, A., Delas, F. and others (2012) 'The effects of wild thyme (Thymus serpyllum L.) essential oil components against ochratoxin-producing Aspergilli', Arhiv za Higijenu Rada i Toksikologiju, 63(4), pp. 457-462. doi:10.2478/10004-1254-63-2012-2309 Preclinical
    https://doi.org/10.2478/10004-1254-63-2012-2309
  6. Jaric, S., Mitrovic, M. and Pavlovic, P (2015) 'Review of Ethnobotanical, Phytochemical, and Pharmacological Study of Thymus serpyllum L', Evidence-Based Complementary and Alternative Medicine, 2015, pp. 101978. doi:10.1155/2015/101978 Meta-analysis / review
    https://doi.org/10.1155/2015/101978
  7. Loziene, K., Vaiciuniene, J. and Venskutonis, P.R (1998) 'Chemical composition of the essential oil of creeping thyme (Thymus serpyllum s.l.) growing wild in Lithuania', Planta Medica, 64(8), pp. 772-773. doi:10.1055/s-2006-957582 Preclinical
    https://doi.org/10.1055/s-2006-957582
  8. Raal, A., Paaver, U., Arak, E. and Orav, A (2004) 'Content and composition of the essential oil of Thymus serpyllum L. growing wild in Estonia', Medicina (Kaunas), 40(8), pp. 795-800. Preclinical
    https://scholar.google.com/scholar?q=Content%20and%20composition%20of%20the%20essential%20oil%20of%20Thymus%20serpyllum%20L.%20growing%20wild%20in%20Estonia
  9. Bozkurt, E., Atmaca, H., Kisim, A., Uzunoglu, S. and others (2012) 'Effects of Thymus serpyllum extract on cell proliferation, apoptosis and epigenetic events in human breast cancer cells', Nutrition and Cancer, 64(8), pp. 1245-1250. doi:10.1080/01635581.2012.719658 Preclinical
    https://doi.org/10.1080/01635581.2012.719658
  10. Jovanovic, A.A., Levic, S.M., Pavlovic, V.B., Markovic, S.B. and others (2021) 'Freeze vs. Spray Drying for Dry Wild Thyme (Thymus serpyllum L.) Extract Formulations: The Impact of Gelatin as a Coating Material', Molecules, 26(13), pp. 3933. doi:10.3390/molecules26133933 Preclinical
    https://doi.org/10.3390/molecules26133933
  11. European Medicines Agency (2010) 'Assessment report on Thymus vulgaris L., herba and Thymus zygis L., herba'. Traditional / reference
    https://scholar.google.com/scholar?q=Assessment%20report%20on%20Thymus%20vulgaris%20L.%2C%20herba%20and%20Thymus%20zygis%20L.%2C%20herba
  12. Kempe, K., Doerfler, G., Bader, D. and Wicht, M (2011) 'Activity of Thymus serpyllum against oral pathogens', 9(1), pp. 23--28. Traditional / reference
    https://scholar.google.com/scholar?q=Activity%20of%20Thymus%20serpyllum%20against%20oral%20pathogens
  13. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
    https://powo.science.kew.org
  14. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.