Plant Comparison
Field restharrow vs Turkey tail
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Field restharrow and Turkey tail: they share 5 indicated uses (cancer (anticancer research), infection (general), wounds, …); 4 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Field restharrow | Turkey tail | Verdict |
|---|---|---|---|
| Cancer (anticancer research) | 2/10 | 9/10 | Stronger for Turkey tail |
| Infection (general) | 2/10 | 5/10 | Stronger for Turkey tail |
| Wounds | 2/10 | 5/10 | Stronger for Turkey tail |
| Skin irritation | 2/10 | 5/10 | Stronger for Turkey tail |
| Inflammation (general) | 2/10 | 5/10 | Stronger for Turkey tail |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Formononetin and its 7-O-glucoside ononin, plus related isoflavones - the signature restharrow constituents (also phytoestrogens).
Pterocarpans and isoflavanones and their glucosides, contributing to antimicrobial and wound-healing activity.
alpha-Onocerin (onocerin), a characteristic triterpene of the genus Ononis.
Caffeic, chlorogenic and p-coumaric acids (antioxidant).
A volatile oil present in the root and aerial parts.
The principal immunomodulating constituents, forming the basis of PSK/PSP extracts.
Protein-bound polysaccharide complex studied extensively as an adjunct immunotherapy.
Minor antioxidant constituents.
Pharmacological Actions
Aquaretic diuretic; the classic irrigation-therapy action of restharrow root (Ononidis radix), used interchangeably for O. arvensis and O. spinosa.
Aqueous root extract reduced adhesion of uropathogenic E. coli to bladder cells (anti-adhesive).
Inhibits IL-8 release via TLR4/LPS and cytosolic phospholipase A2alpha (restharrow root).
Analgesic activity of Ononis extract in animals (congener O. spinosa).
Protective against ethanol-induced gastric mucosal injury (congener O. spinosa).
Ononis isoflavones showed chemopreventive/antiproliferative activity against breast cancer cells (preclinical).
Traditional & Indicated Uses
inferred from anticancer action
Aquaretic diuretic for irrigation therapy of the urinary tract.
Anti-adhesive activity against uropathogenic E. coli.
inferred from diuretic / urinary 'gravel' traditional use
inferred from diuretic (aquaretic) action
inferred from antimicrobial action
Isoflavonoid wound-healing agents from restharrow root.
inferred from anti-inflammatory and traditional skin/eczema use
inferred from anti-inflammatory action
inferred from anticancer action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
A safety signal exists in the genus: an Ononis spinosa root extract showed hepatotoxic effects at higher doses in animals (alongside analgesic activity). Avoid excessive or prolonged use, and use caution in liver disease.
Used as an aquaretic for irrigation therapy of the urinary tract, restharrow should be taken with a generous fluid intake; it should NOT be used for 'flushing' when there is oedema due to impaired heart or kidney function (standard irrigation-therapy caution).
Generally very safe and well tolerated. Rare cases of digestive upset or allergic reaction. No significant known drug interactions at normal doses. The PSK pharmaceutical form is used safely alongside standard cancer treatments. Suitable for most adults.
External Ids
Synonyms
Not documented
Botanical Description
A tough, deep-rooted perennial herb or low subshrub of the pea family, 30-80 cm tall, sometimes bearing soft spines. It has a very long, woody, tenacious taproot - so strong it was said to stop (arrest) the harrow, giving 'rest-harrow' its name. The stems are hairy and sticky, often reddish, and clothed in small trifoliolate (clover-like) leaves with toothed leaflets. The flowers are typical pea flowers, pink to purplish-pink (occasionally white), borne singly or in pairs in the leaf axils. Field restharrow (O. arvensis) is generally less spiny than its close relative spiny restharrow (O. spinosa).[8, 10]
Bracket fungus (not a true plant) forming thin, tough, fan-shaped, overlapping shelves on dead or decaying hardwood, with a velvety, concentrically zoned upper surface in bands of brown, tan, cream, blue-grey and rust, and a white, minutely pored underside.
Habitat
Rough grassland, field margins, roadsides, dunes and dry, sandy or calcareous waste ground across Europe, western Asia and parts of North Africa. As a deep-rooted, nitrogen-fixing legume it colonises poor, disturbed soils and was historically a troublesome weed of arable fields (hence 'restharrow').[8]
Grows on dead, dying or fallen hardwood logs, stumps and branches in woodlands worldwide, including Europe, Asia and North America.
Harvesting
The root (Ononidis radix) is the principal medicinal part, dug in autumn from the second year onward and dried; the aerial flowering parts are also gathered in summer. The long woody taproot is cleaned and cut before drying for decoctions and infusions.[8]
Fresh brackets are harvested by cutting from the wood; for medicinal use the tough fruiting body is typically dried and then decocted (simmered) for a long time, or extracted, since the beneficial polysaccharides are not well-extracted by simple infusion.
Traditional Uses
Restharrow root has a long place in European herbal medicine as a gentle aquaretic diuretic used for 'irrigation therapy' of the urinary tract - to increase urine flow in cystitis, urinary gravel and stones, and to flush the bladder. Field restharrow (Ononis arvensis) is used interchangeably with the officinal spiny restharrow (O. spinosa, Ononidis radix). The root and flowering herb have also been used as a mild anti-inflammatory, for skin complaints and eczema, for rheumatic conditions, and (as a decoction or gargle) for the mouth and throat. The isoflavone-rich root is a folk remedy in central and eastern European traditions.[8, 13]
Turkey tail has a long history of use in traditional Chinese medicine (as yun zhi) and is one of the most researched medicinal mushrooms, with standardized polysaccharide-K (PSK) and polysaccharopeptide (PSP) extracts used clinically in Japan and China alongside conventional cancer treatment to support immune function.[11, 12, 13]
Preparations
The dried root simmered in water and taken as an aquaretic diuretic for irrigation of the urinary tract; the classic restharrow preparation.
The flowering aerial parts infused as a milder diuretic and anti-inflammatory tea.
A root decoction used traditionally as a mouth/throat gargle and as a wash for skin complaints.
Dried fruiting body simmered in water for an extended period (often 1-2 hours) to extract the beta-glucan polysaccharides, then strained.
Standardized polysaccharide-K (PSK) or polysaccharopeptide (PSP) extract, the pharmaceutical-grade forms used in clinical research.
References
Drug Class Interactions
Not documented
Pairings
Classic urinary irrigation-therapy pairing: both are aquaretic diuretics used to increase urine flow in cystitis and urinary gravel.[13]
Both are traditional diuretic 'flushing' herbs for irrigation therapy of the urinary tract.[13]
Both are Fabaceae rich in the isoflavone phytoestrogen formononetin; combined use adds to phytoestrogen exposure - use caution in hormone-sensitive conditions.[1]
Not documented
Lookalikes Review
Dosage
Not documented
Clinical research on PSK commonly uses around 3 g daily in divided doses. Educational reference only, not a prescription.
Dangerous Lookalikes
Not documented
References & Sources
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https://scholar.google.com/scholar?q=Capillary%20electrophoretic%20analysis%20of%20hydroxycinnamic%20acids%20from%20Ononis%20arvensis%20L. - Spilkova, J. and Hubik, J (1982) 'Pharmacognosy study of Ononis arvensis L. II. Flavonoids and onocerin in the drug', Ceskoslovenska Farmacie, 31(1), pp. 24-26. Preclinical
https://scholar.google.com/scholar?q=Pharmacognosy%20study%20of%20Ononis%20arvensis%20L.%20II.%20Flavonoids%20and%20onocerin%20in%20the%20drug - Rezacova, A. and Spilkova, J. and Hubik, J (1978) 'A pharmacognostic study of the species Ononis arvensis L', Ceskoslovenska Farmacie, 27(10), pp. 452-455. Traditional / reference
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https://scholar.google.com/scholar?q=A%20comparative%20phytochemical%20study%20of%20the%20roots%20of%20Ononis%20arvensis%20L.%20and%20Ononis%20spinosa%20L. - Sichinava, M.B. and Mchelidze, K.Z. and Churadze, M.V. and Alaniia, M.D. and Aneli, D.N (2014) 'Chemical composition and microstructural peculiarities of overground and underground vegetative organs of field restharrow (Ononis arvensis L.)', Georgian Medical News, (231), pp. 88-94. Preclinical
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https://doi.org/10.3109/02656736.2015.1046953 - Scarpari, M., Reverberi, M., Parroni, A., Scala, V. and others (2017) 'Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects', PLoS One, 12(8), pp. e0171412. doi:10.1371/journal.pone.0171412 Preclinical
https://doi.org/10.1371/journal.pone.0171412 - Lysakowska, P., Sobota, A. and Wirkijowska, A (2023) 'Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production - A Review', Molecules, 28(14), pp. 5393. doi:10.3390/molecules28145393 Meta-analysis / review
https://doi.org/10.3390/molecules28145393 - Wang, K.F., Sui, K.Y., Guo, C. and Liu, C.Z (2017) 'Quorum sensing molecule-farnesol increased the production and biological activities of extracellular polysaccharide from Trametes versicolor', International Journal of Biological Macromolecules, 104(Pt A), pp. 377-383. doi:10.1016/j.ijbiomac.2017.06.053 Preclinical
https://doi.org/10.1016/j.ijbiomac.2017.06.053 - Chu, K.K., Ho, S.S. and Chow, A.H (2002) 'Coriolus versicolor: a medicinal mushroom with promising immunotherapeutic values', 42(9), pp. 976--984. doi:10.1177/0091270002042009004 Traditional / reference
https://doi.org/10.1177/0091270002042009004 - Standish, L.J., Wenner, C.A., Sweet, E.S., Bridge, C., Nelson, A., Martzen, M., Novack, J. and Torkelson, C (2008) 'Trametes versicolor mushroom immune therapy in breast cancer', 6(3), pp. 122--128. Traditional / reference
https://scholar.google.com/scholar?q=Trametes%20versicolor%20mushroom%20immune%20therapy%20in%20breast%20cancer - Wasser, S.P (2011) 'Current findings, future trends, and unsolved problems in studies of medicinal mushrooms', 89(5), pp. 1323--1332. doi:10.1007/s00253-010-3067-4 Randomized trial
https://doi.org/10.1007/s00253-010-3067-4 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Macalester College, Katharine Ordway Natural History Study Area 'Turkey Tail Fungus (Trametes versicolor)'. Available at: https://www.macalester.edu/ordway/biodiversity/inventory/turkeytailfungus/ Traditional / reference
https://www.macalester.edu/ordway/biodiversity/inventory/turkeytailfungus/ - Missouri Department of Conservation 'False Turkey Tail (Stereum ostrea)'. Available at: https://mdc.mo.gov/discover-nature/field-guide/false-turkey-tail Traditional / reference
https://mdc.mo.gov/discover-nature/field-guide/false-turkey-tail - Kuo, Michael 'Stereum ostrea (False Turkey Tail)'. Available at: https://www.mushroomexpert.com/stereum_ostrea.html Traditional / reference
https://www.mushroomexpert.com/stereum_ostrea.html
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.