Plant Comparison
Black Cumin vs Breckland Thyme
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Black Cumin and Breckland Thyme: they share 9 indicated uses (acid reflux, arthritis / joint pain, cancer (anticancer research), …); 5 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Black Cumin | Breckland Thyme | Verdict |
|---|---|---|---|
| Acid reflux | 5/10 | 1/10 | Stronger for Black Cumin |
| Arthritis / joint pain | 5/10 | 1/10 | Stronger for Black Cumin |
| Cancer (anticancer research) | 7/10 | 2/10 | Stronger for Black Cumin |
| Indigestion | 5/10 | 1/10 | Stronger for Black Cumin |
| Infection (general) | 5/10 | 1/10 | Stronger for Black Cumin |
| Inflammation (general) | 5/10 | 1/10 | Stronger for Black Cumin |
| Respiratory support | 5/10 | 1/10 | Stronger for Black Cumin |
| Skin irritation | 5/10 | 1/10 | Stronger for Black Cumin |
| Wounds | 5/10 | 1/10 | Stronger for Black Cumin |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
The principal bioactive constituent of the seed oil, responsible for much of its anti-inflammatory, antioxidant and antimicrobial activity.
The aromatic fraction of the seed, contributing antimicrobial and antioxidant activity.
The bulk lipid fraction of the seed (roughly a third of seed weight by weight), the carrier for the fat-soluble thymoquinone.
Minor isoquinoline-type alkaloids studied for antioxidant activity.
Triterpene saponin studied for anticancer and antiparasitic activity.
The volatile oil, dominated by thymol and carvacrol, gives most of the antimicrobial and antioxidant activity.
Contribute additional antioxidant activity.
Minor constituents studied for anti-inflammatory activity.
Pharmacological Actions
Traditional & Indicated Uses
inferred from gastroprotective action
inferred from anti-inflammatory action
inferred from analgesic action
inferred from digestive action
inferred from antidiabetic action
inferred from anticancer action
inferred from immunomodulator action
inferred from analgesic action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from antidiabetic action
inferred from anti-inflammatory action
inferred from gastroprotective action
inferred from anti-inflammatory action
inferred from anticancer action
inferred from gastroprotective action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
Generally well-tolerated in clinical trials at doses up to 200 mg/day of oil for 90 days. Potential side effects may include mild gastrointestinal discomfort. Contraindicated during pregnancy due to potential uterine stimulant effects. May interact with immunosuppressants and antidiabetic medications. Allergic reactions possible in sensitive individuals. Consult healthcare provider before use, especially with concurrent medications.
Duke (2002) describes black cumin (Nigella sativa) as one of the most multi-active medicinal spices, with experimental evidence for bronchodilation, immunostimulation, hepatoprotection, and antihistaminic activity. The prophet Muhammad reportedly described it as 'a cure for all things except death.' Key bioactive compounds include thymoquinone and nigellone. Antihistaminic and bronchodilatory activity supports its traditional use in asthma and allergic conditions. Duke notes it is generally safe at culinary amounts but recommends caution with medicinal doses in pregnancy due to potential uterotonic effects (Duke, 2002).
Generally safe at culinary doses. Essential oil is highly concentrated and must be diluted before topical use; undiluted application can cause skin sensitisation. Not recommended internally during pregnancy (uterine stimulant effects possible). Phenol-rich thyme preparations should be avoided long-term in high doses. May potentiate anticoagulant medications.
Duke (2002) rates Thymus vulgaris (garden thyme, closely related to breckland thyme) as +++ with clinical evidence (score 2) for antibacterial, bronchospasmolytic, and antispasmodic activities, consistent with Commission E and WHO approvals for bronchitis and upper respiratory catarrh. The primary active constituent is thymol, with carvacrol as a secondary compound. Dose: 1–2 g dried herb as tea three times daily. The plant demonstrates COX-2 inhibitory activity and calcium antagonism, which may explain its antispasmodic effects (Duke, 2002).
External Ids
Botanical Description
Annual herb (Ranunculaceae), 20-90 cm tall, with an erect, branched stem and finely divided, pinnately dissected, fern-like leaves. Delicate pale blue-white (occasionally pale purple) flowers, each with 5-10 petal-like sepals, are surrounded by a feathery bract collar. The fruit is an inflated, many-celled capsule that dries and splits to release numerous small, black, angular seeds - the medicinal part.[1]
Low, mat-forming, aromatic perennial subshrub with tiny, oval, strongly aromatic leaves on trailing, wiry, hairy stems that root as they spread. Small, pinkish-purple, two-lipped flowers are borne in dense whorled clusters at the stem tips.
Habitat
Native to the Mediterranean basin, southern Europe, western Asia and North Africa, and widely cultivated as a spice and medicinal crop across the Middle East, South Asia and North Africa; grows in cultivated fields and on disturbed ground.[1]
Grows on dry, sunny heath, grassland, rocky ground and sandy soils; native to Europe and widely distributed across the northern temperate zone.
Harvesting
Seed capsules are harvested once dried and brown (late summer), then threshed to release the small black seeds. Seed is stored whole and either used directly or cold-pressed for oil shortly before use to preserve the volatile thymoquinone-rich fraction.[1]
The flowering aerial parts (flower and leaf) are cut at the start of flowering in summer and dried in a warm, shaded, airy place.
Traditional Uses
One of the most celebrated medicinal seeds in Middle Eastern and Islamic traditional medicine - known as 'Habbatul Barakah' (the blessed seed) - black seed has traditionally been used for digestive complaints, respiratory conditions (asthma, cough), pain, inflammation, skin conditions and as a general tonic. Modern research on its principal constituent thymoquinone supports broad anti-inflammatory, antioxidant, antimicrobial, antidiabetic and immunomodulatory activity.[1, 2, 9]
Preparations
Dried flowering herb infused in hot water as a traditional respiratory and digestive tea.
Dosage
References
Drug Class Interactions
Not documented
Lookalikes Review
References & Sources
- Hannan, M.A., Rahman, M.A., Sohag, A.A.M., Uddin, M.J., Dash, R., Sikder, M.H., Rahman, M.S., Timalsina, B., Munni, Y.A. and Sarker, P.P (2021) 'Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety', Nutrients, 13(6), pp. 1784. doi:10.3390/nu13061784 Meta-analysis / review
https://doi.org/10.3390/nu13061784 - Ahmad, A., Husain, A., Mujeeb, M., Khan, S.A., Najmi, A.K., Siddique, N.A., Damanhouri, Z.A. and Anwar, F (2013) 'A review on therapeutic potential of Nigella sativa: A miracle herb', Asian Pacific Journal of Tropical Biomedicine, 3(5), pp. 337-352. doi:10.1016/S2221-1691(13)60075-1 Meta-analysis / review
https://doi.org/10.1016/S2221-1691(13)60075-1 - Chatterjee, G., Saha, A.K., Khurshid, S. and Saha, A (2025) 'A Comprehensive Review of the Antioxidant, Antimicrobial, and Therapeutic Efficacies of Black Cumin (Nigella sativa L.) Seed Oil and Its Thymoquinone', Journal of Medicinal Food, 28(4), pp. 325-339. doi:10.1089/jmf.2024.k.0149 Meta-analysis / review
https://doi.org/10.1089/jmf.2024.k.0149 - Majdalawieh, A.F. and Fayyad, M.W (2015) 'Immunomodulatory and anti-inflammatory action of Nigella sativa and thymoquinone: A comprehensive review', International Immunopharmacology, 28(1), pp. 295-304. doi:10.1016/j.intimp.2015.06.023 Meta-analysis / review
https://doi.org/10.1016/j.intimp.2015.06.023 - Shaukat, A., Zaidi, A., Anwar, H. and Kizilbash, N (2023) 'Mechanism of the antidiabetic action of Nigella sativa and Thymoquinone: a review', Frontiers in Nutrition, 10, pp. 1126272. doi:10.3389/fnut.2023.1126272 Meta-analysis / review
https://doi.org/10.3389/fnut.2023.1126272 - Beheshti, F., Khazaei, M. and Hosseini, M (2016) 'Neuropharmacological effects of Nigella sativa', Avicenna Journal of Phytomedicine, 6(1), pp. 104-116. Meta-analysis / review
https://scholar.google.com/scholar?q=Neuropharmacological%20effects%20of%20Nigella%20sativa - Shafiq, H., Ahmad, A., Masud, T. and Kaleem, M (2014) 'Cardio-protective and anti-cancer therapeutic potential of Nigella sativa', Iranian Journal of Basic Medical Sciences, 17(12), pp. 967-979. Meta-analysis / review
https://scholar.google.com/scholar?q=Cardio-protective%20and%20anti-cancer%20therapeutic%20potential%20of%20Nigella%20sativa - Bordoni, L., Fedeli, D., Nasuti, C., Maggi, F., Papa, F., Wabitsch, M., De Caterina, R. and Gabbianelli, R (2019) 'Antioxidant and Anti-Inflammatory Properties of Nigella sativa Oil in Human Pre-Adipocytes', Antioxidants, 8(2), pp. 51. doi:10.3390/antiox8020051 Preclinical
https://doi.org/10.3390/antiox8020051 - Gholamnezhad, Z., Havakhah, S. and Boskabady, M.H (2016) 'Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review', Journal of Ethnopharmacology, 190, pp. 372-386. doi:10.1016/j.jep.2016.06.061 Meta-analysis / review
https://doi.org/10.1016/j.jep.2016.06.061 - Ali, B.H. and Blunden, G (2003) 'Pharmacological and toxicological properties of Nigella sativa', Phytotherapy Research, 17(4), pp. 299-305. doi:10.1002/ptr.1309 Meta-analysis / review
https://doi.org/10.1002/ptr.1309 - Al-Attass, S.A., Zahran, F.M. and Turkistany, S.A (2016) 'Nigella sativa and its active constituent thymoquinone in oral health', Saudi Medical Journal, 37(3), pp. 235-244. doi:10.15537/smj.2016.3.13006 Meta-analysis / review
https://doi.org/10.15537/smj.2016.3.13006 - Ahmad A, Husain A, Mujeeb M, et al. A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pac J Trop Biomed. 2013;3 (2013) ';3(5):337-352', 3(5). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC3642442/ Traditional / reference
https://pmc.ncbi.nlm.nih.gov/articles/PMC3642442/ - Darakhshan S, Bidmeshki Pour A, Hosseinzadeh Colagar A, Sisakhtnezhad S. Thymoquinone and its therapeutic potentials. Pharmacol Res. 2015;95-96:138-158. https://pmc.ncbi.nlm.nih.gov/articles/PMC4387230/ (2015) ';95-96:138-158'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC4387230/ Traditional / reference
https://pmc.ncbi.nlm.nih.gov/articles/PMC4387230/ - Forouzanfar F, Bazzaz BSF, Hosseinzadeh H. A review of ethnobotany, phytochemistry, antimicrobial pharmacology and toxicology of Nigella sativa L. Biomed Pharmacother. 2021;142:112040. https://www.sciencedirect.com/science/article/pii/S0753332221009665 (2021) ';142:112040'. Available at: https://www.sciencedirect.com/science/article/pii/S0753332221009665 Traditional / reference
https://www.sciencedirect.com/science/article/pii/S0753332221009665 - Gholamnezhad Z, Keyhanmanesh R, Boskabady MH. Anti-inflammatory, antioxidant, and immunomodulatory aspects of Nigella sativa for its preventive and bronchodilatory effects on obstructive respiratory diseases. Biomed Pharmacother. 2021;136:111240. https://www.sciencedirect.com/science/article/pii/S0753332221002778 (2021) ';136:111240'. Available at: https://www.sciencedirect.com/science/article/pii/S0753332221002778 Traditional / reference
https://www.sciencedirect.com/science/article/pii/S0753332221002778 - Hannan MA, Rahman MA, Sohag AAM, et al. Black cumin (2021) ';13(6):1784', 13(6). doi:10.3389/fphar.2021.625386/full Randomized trial
https://doi.org/10.3389/fphar.2021.625386/full - Kooti W, Hasanzadeh-Noohi Z, Sharafi-Ahvazi N, et al. Phytochemistry, pharmacology, and therapeutic uses of black seed (2016) ';22(3):231-237', 22(3). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8225153/ Traditional / reference
https://pmc.ncbi.nlm.nih.gov/articles/PMC8225153/ - Tavakkoli A, Mahdian V, Razavi BM, Hosseinzadeh H. Review on clinical trials of black seed (2017) ';20(3):179-193', 20(3). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5633670/ Traditional / reference
https://pmc.ncbi.nlm.nih.gov/articles/PMC5633670/ - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Saadati, S., Naseri, K., Asbaghi, O., Abhari, K., Zhang, P., Li, H.B. and Gan, R.Y (2022) 'Nigella sativa supplementation improves cardiometabolic indicators in population with prediabetes and type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials', Frontiers in Nutrition, 9, pp. 977756. doi:10.3389/fnut.2022.977756 Meta-analysis / review
https://doi.org/10.3389/fnut.2022.977756 - Willcox, M.L., Elugbaju, C., Al-Anbaki, M., Lown, M. and Graz, B (2021) 'Effectiveness of Medicinal Plants for Glycaemic Control in Type 2 Diabetes: An Overview of Meta-Analyses of Clinical Trials', Frontiers in Pharmacology, 12, pp. 777561. doi:10.3389/fphar.2021.777561 Meta-analysis / review
https://doi.org/10.3389/fphar.2021.777561 - Daryabeygi-Khotbehsara, R., Golzarand, M., Ghaffari, M.P. and Djafarian, K (2017) 'Nigella sativa improves glucose homeostasis and serum lipids in type 2 diabetes: a systematic review and meta-analysis', Complementary Therapies in Medicine, 35, pp. 6-13. doi:10.1016/j.ctim.2017.08.016 Meta-analysis / review
https://doi.org/10.1016/j.ctim.2017.08.016 - Sahebkar, A., Soranna, D., Liu, X., Thomopoulos, C., Simental-Mendia, L.E., Derosa, G., Maffioli, P. and Parati, G (2016) 'A systematic review and meta-analysis of randomized controlled trials investigating the effects of supplementation with Nigella sativa (black seed) on blood pressure', Journal of Hypertension, 34(11), pp. 2127-2135. doi:10.1097/HJH.0000000000001049 Meta-analysis / review
https://doi.org/10.1097/HJH.0000000000001049 - Kavyani, Z., Musazadeh, V., Safaei, E., Mohammadi Asmaroud, M., Khashakichafi, F., Ahrabi, S.S. and Dehghan, P (2023) 'Antihypertensive effects of Nigella sativa supplementation: an updated systematic review and meta-analysis of randomized controlled trials', Phytotherapy Research, 37(8), pp. 3224-3238. doi:10.1002/ptr.7891 Meta-analysis / review
https://doi.org/10.1002/ptr.7891
- Jalil, B., Pischel, I., Feistel, B., Suarez, C. and others (2024) 'Wild thyme (Thymus serpyllum L.): a review of the current evidence of nutritional and preventive health benefits', Frontiers in Nutrition, 11, pp. 1380962. doi:10.3389/fnut.2024.1380962 Meta-analysis / review
https://doi.org/10.3389/fnut.2024.1380962 - Sonmezdag, A.S., Kelebek, H. and Selli, S (2016) 'Characterization of aroma-active and phenolic profiles of wild thyme (Thymus serpyllum) by GC-MS-Olfactometry and LC-ESI-MS/MS', Journal of Food Science and Technology, 53(4), pp. 1957-1965. doi:10.1007/s13197-015-2144-1 Preclinical
https://doi.org/10.1007/s13197-015-2144-1 - Pavlic, B., Mrkonjic, Z., Teslic, N., Kljakic, A.C. and others (2022) 'Natural Deep Eutectic Solvent (NADES) Extraction Improves Polyphenol Yield and Antioxidant Activity of Wild Thyme (Thymus serpyllum L.) Extracts', Molecules, 27(5), pp. 1508. doi:10.3390/molecules27051508 Preclinical
https://doi.org/10.3390/molecules27051508 - Mrkonjic, Z., Kaplan, M., Milosevic, S., Bozovic, D. and others (2024) 'Green Extraction Approach for Isolation of Bioactive Compounds in Wild Thyme (Thymus serpyllum L.) Herbal Dust-Chemical Profile, Antioxidant and Antimicrobial Activity and Comparison with Conventional Techniques', Plants, 13(6), pp. 897. doi:10.3390/plants13060897 Preclinical
https://doi.org/10.3390/plants13060897 - Sokolic-Mihalak, D., Frece, J., Slavica, A., Delas, F. and others (2012) 'The effects of wild thyme (Thymus serpyllum L.) essential oil components against ochratoxin-producing Aspergilli', Arhiv za Higijenu Rada i Toksikologiju, 63(4), pp. 457-462. doi:10.2478/10004-1254-63-2012-2309 Preclinical
https://doi.org/10.2478/10004-1254-63-2012-2309 - Jaric, S., Mitrovic, M. and Pavlovic, P (2015) 'Review of Ethnobotanical, Phytochemical, and Pharmacological Study of Thymus serpyllum L', Evidence-Based Complementary and Alternative Medicine, 2015, pp. 101978. doi:10.1155/2015/101978 Meta-analysis / review
https://doi.org/10.1155/2015/101978 - Loziene, K., Vaiciuniene, J. and Venskutonis, P.R (1998) 'Chemical composition of the essential oil of creeping thyme (Thymus serpyllum s.l.) growing wild in Lithuania', Planta Medica, 64(8), pp. 772-773. doi:10.1055/s-2006-957582 Preclinical
https://doi.org/10.1055/s-2006-957582 - Raal, A., Paaver, U., Arak, E. and Orav, A (2004) 'Content and composition of the essential oil of Thymus serpyllum L. growing wild in Estonia', Medicina (Kaunas), 40(8), pp. 795-800. Preclinical
https://scholar.google.com/scholar?q=Content%20and%20composition%20of%20the%20essential%20oil%20of%20Thymus%20serpyllum%20L.%20growing%20wild%20in%20Estonia - Bozkurt, E., Atmaca, H., Kisim, A., Uzunoglu, S. and others (2012) 'Effects of Thymus serpyllum extract on cell proliferation, apoptosis and epigenetic events in human breast cancer cells', Nutrition and Cancer, 64(8), pp. 1245-1250. doi:10.1080/01635581.2012.719658 Preclinical
https://doi.org/10.1080/01635581.2012.719658 - Jovanovic, A.A., Levic, S.M., Pavlovic, V.B., Markovic, S.B. and others (2021) 'Freeze vs. Spray Drying for Dry Wild Thyme (Thymus serpyllum L.) Extract Formulations: The Impact of Gelatin as a Coating Material', Molecules, 26(13), pp. 3933. doi:10.3390/molecules26133933 Preclinical
https://doi.org/10.3390/molecules26133933 - European Medicines Agency (2010) 'Assessment report on Thymus vulgaris L., herba and Thymus zygis L., herba'. Traditional / reference
https://scholar.google.com/scholar?q=Assessment%20report%20on%20Thymus%20vulgaris%20L.%2C%20herba%20and%20Thymus%20zygis%20L.%2C%20herba - Kempe, K., Doerfler, G., Bader, D. and Wicht, M (2011) 'Activity of Thymus serpyllum against oral pathogens', 9(1), pp. 23--28. Traditional / reference
https://scholar.google.com/scholar?q=Activity%20of%20Thymus%20serpyllum%20against%20oral%20pathogens - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.