Plant Comparison

Catnip vs Cacao

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ACatnipNepeta catariaLamiaceaeFull monograph →
Plant BCacaoTheobroma cacaoMalvaceaeFull monograph →

At a glance

Catnip and Cacao: they share 5 indicated uses (arthritis / joint pain, bloating, indigestion, …); 2 pharmacological actions in common.

CatnipCacao
Constituents34
Pharmacological actions44
Indicated uses98
Safety notes22
Cited sources1714
Indicated uses
Only Catnip
Infection (general)Insomnia / sleeplessnessRespiratory supportWounds
Shared (5)
Arthritis / joint painBloatingIndigestionInflammation (general)Skin irritation
Only Cacao
Cardiovascular / heart healthCognitive functionMemory
Pharmacological actions
Only Catnip
AntimicrobialSedative / sleep support
Shared (2)
Anti-inflammatoryDigestive aid
Only Cacao
AntioxidantNeuroprotective / cognition support

Evidence face-off — shared uses

ConditionCatnipCacaoVerdict
Arthritis / joint pain1/103/10Stronger for Cacao
Bloating1/103/10Stronger for Cacao
Indigestion1/103/10Stronger for Cacao
Inflammation (general)1/103/10Stronger for Cacao
Skin irritation1/103/10Stronger for Cacao

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Iridoid monoterpenes (nepetalactone)[2, 6]

The characteristic volatile iridoid responsible for the cat-attractant effect and studied for sedative, antimicrobial and insect-repellent activity.

Terpenes / terpenoids
Essential oil[5]

Rich in nepetalactone isomers along with other monoterpenes; studied for antimicrobial and antioxidant activity.

Essential (volatile) oil
Flavonoids[3]

Contribute to the antioxidant activity of the aerial parts.

Flavonoids
Methylxanthines (theobromine, caffeine)[11]

Theobromine is the dominant methylxanthine and the main stimulant/bronchodilator constituent, with lesser amounts of caffeine.

Flavanols (epicatechin, catechin, procyanidins)[1, 2]

The principal bioactive polyphenols, responsible for most of cacao's antioxidant and cardiovascular activity.

CatechinsProanthocyanidinsFlavonoids
Phenylethylamine[11]

A trace amine sometimes linked to cacao's reputed mood-elevating effects.

Cocoa butter (fatty acids)[12]

The fat fraction of the seed, classified as emollient and used in both food and topical products.

Pharmacological Actions

Anti-inflammatory[12, 13, 14]
Antimicrobial[3, 5, 7, 12, 13, 14]
Digestive aid[9, 12, 13, 14]
Sedative / sleep support[12, 13, 14]
Anti-inflammatory[1, 5, 8, 11, 12, 13]
Antioxidant[1, 3, 5, 7, 10, 11, 12, 13]
Digestive aid[11, 12, 13]
Neuroprotective / cognition support[11, 12, 13]

Traditional & Indicated Uses

Arthritis / joint pain[12, 13, 14]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bloating[9, 12, 13, 14]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Bloating
Indigestion[9, 12, 13, 14]Traditional · 1/10

inferred from digestive action

Evidence: 1
Label: Indigestion
Infection (general)[3, 5, 12, 13, 14]Traditional · 2/10

inferred from antimicrobial action

Evidence: 2
Label: Infection (general)
Inflammation (general)[12, 13, 14]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Insomnia / sleeplessness[12, 13, 14]Traditional · 1/10

inferred from sedative action

Evidence: 1
Label: Insomnia / sleeplessness
Respiratory support[12, 13, 14]Traditional · 1/10
Evidence: 1
Label: Respiratory support
Skin irritation[12, 13, 14]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[12, 13, 14]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Arthritis / joint pain[11, 12, 13]Limited · 3/10

inferred from anti-inflammatory action

Evidence: 3
Label: Arthritis / joint pain
Bloating[11, 12, 13]Limited · 3/10

inferred from digestive action

Evidence: 3
Label: Bloating
Cardiovascular / heart health[1, 2, 3, 4, 5, 6, 9, 11, 12, 13]Strong · 10/10
Evidence: 10
Label: Cardiovascular / heart health
Cognitive function[11, 12, 13]Limited · 3/10

inferred from neuroprotective action

Evidence: 3
Label: Cognitive function
Indigestion[11, 12, 13]Limited · 3/10

inferred from digestive action

Evidence: 3
Label: Indigestion
Inflammation (general)[11, 12, 13]Limited · 3/10

inferred from anti-inflammatory action

Evidence: 3
Label: Inflammation (general)
Memory[11, 12, 13]Limited · 3/10

inferred from neuroprotective action

Evidence: 3
Label: Memory
Skin irritation[8, 11, 12, 13]Limited · 3/10

inferred from anti-inflammatory action

Evidence: 3
Label: Skin irritation

Safety, Cautions & Contraindications

Safety note[12, 13, 14]Caution

Pregnancy: Do not use (traditional concern around stimulating menstruation/uterus) (Health Canada, n.d.). Breastfeeding: Health Canada advises talk to a healthcare professional first (Health Canada, n.d.). Kids: It’s often described as a “gentle” traditional tea, but large amounts are not a good idea—there’s a published case where a toddler became very sleepy/“slowed down” after consuming a lot. Keep catnip tea away from toddlers unless a clinician advises it (Osterhoudt et al., 1997). Sedatives / alcohol: Catnip can be calming, so don’t stack it with other sedating herbs/sleep meds/alcohol (you could get extra drowsy) (WebMD, n.d.a). Essential oil caution: Catnip essential oil is concentrated. Research notes it may cause mild skin irritation for some people—always dilute, patch test, and never treat it like “tea.” (Reichert et al., 2019)

Safety note[12, 13, 14, 15]Caution

Duke (2002) describes catnip primarily as a sedative, diaphoretic, and emmenagogue with experimental (score 1) support. It has demonstrated uterotonic and oxytocic activity, making it contraindicated in pregnancy. The active compounds include nepetalactone and iridoids. Catnip is classified as a mild nervine and antispasmodic in traditional North American herbal medicine, though clinical trials are lacking. Due to its emmenagogue and uterotonic properties, medicinal-dose use should be avoided during pregnancy (Duke, 2002).

Safety note[11, 12, 13]Caution

• Stimulant effect (most common issue): cacao naturally contains theobromine (and some caffeine). In larger amounts it can feel like a “gentle coffee”: faster heartbeat, restlessness, trouble sleeping. • Heavy metals (quality matters): cocoa/chocolate can contain cadmium and lead from soil and processing. For frequent use (especially powders, dark chocolate, “ceremonial” paste), choose brands that publish lab tests. • Pregnancy (extra caution late pregnancy): some research suggests very polyphenol-rich foods (including cocoa/dark chocolate) could affect fetal circulation in late pregnancy. This is not “everyone must avoid chocolate,” but high-dose cacao drinks are something to discuss with a clinician if pregnant—especially in the 3rd trimester. • Breastfeeding: moderate chocolate/cacao is usually fine, but very large amounts can affect some infants (stimulation/irritability) because stimulant compounds can pass into milk in small amounts. • If you’re sensitive: cacao can worsen reflux/heartburn, trigger migraines in some people, or cause nausea—especially in strong ceremonial-style servings. • Medication caution: if you take stimulant-sensitive meds, have heart rhythm issues, severe anxiety, or use MAOI antidepressants, treat high-dose cacao drinks like a stimulant and be cautious

Safety note[11, 12, 13, 14]Info

Duke (2002) notes that cacao is primarily known for its cardiotonic, CNS-stimulant, and broncholytic activities at the experimental level (score 1). Theobromine is identified as the principal active constituent responsible for mild bronchodilation and cardiovascular stimulation. Cocoa butter is classified as emollient (score 1). Chocolate's content of phenylethylamine may contribute to reported aphrodisiac properties. Duke notes that excessive consumption may be cariogenic and pro-acneic, and cocoa is a known allergen in sensitive individuals (Duke, 2002).

External Ids

Gbif: 5341499
Wikidata: Q161139
Gbif: 3152205
Wikidata: Q42385

Botanical Description

Perennial herb, 30-100 cm tall, with greyish-green, downy, square stems typical of the mint family. Leaves are opposite, triangular-ovate with scalloped or toothed margins, grey-green above and softly felted (whitish) beneath, releasing a minty-lemony aroma when crushed. Small white flowers, spotted with purple or pink, are borne in dense terminal and axillary spikes. Nepetalactone, the volatile compound famous for its effect on cats, is concentrated in glandular hairs on the leaves and stems.[9]

Height: 30-100 cm
Habit: Erect, bushy, greyish-downy perennial herb
Leaves: Opposite, triangular-ovate, scalloped/toothed, felted white beneath
Flowers: Small, white with purple/pink spotting, in dense terminal and axillary spikes
Stem: Square, greyish-green, downy
Root: Fibrous perennial rootstock
Fruit: Four small nutlets (typical Lamiaceae schizocarp)
Flowering Period: June-September

Small evergreen tree (Malvaceae), 4-8 m tall (up to 10 m unpruned), with a dense, spreading crown. Leaves are large, glossy and oblong. Small pink-white flowers are borne directly on the trunk and older branches (cauliflory), followed by large, ridged, football-shaped pods that ripen from green to yellow/orange/red-purple, each containing 20-60 seeds (the cocoa beans) embedded in sweet white pulp.[1]

Height: 4-8 m (up to 10 m unpruned)
Habit: Small evergreen tree, cauliflorous (flowers/pods on the trunk)
Leaves: Large, glossy, oblong
Flowers: Small, pink-white, borne directly on the trunk and older branches
Stem: Woody trunk, flowers and pods arising directly from it
Root: Moderate, spreading root system
Fruit: Large, ridged pod containing 20-60 seeds in sweet white pulp
Flowering Period: Can flower year-round in tropical conditions

Habitat

Native to Europe and temperate Asia and widely naturalised in North America; grows on disturbed, sunny ground - roadsides, waste places, hedgebanks and dry, calcareous or well-drained soils.[9]

Native to the tropical rainforest understorey of Central and South America (the Amazon and Orinoco basins), now cultivated throughout the tropics within about 20 degrees of the equator (notably West Africa, Southeast Asia and South America), requiring warm, humid, shaded conditions.[1]

Harvesting

The flowering aerial parts (leaf, stem and flower) are cut at or just before flowering (summer), when volatile nepetalactone content is highest, and dried quickly out of direct light.[2, 9]

Parts: Leaf, Stem, Flower
Season: Summer, at or just before flowering

Ripe pods are hand-harvested, cut open, and the seeds (with pulp) are removed, fermented for several days - essential for developing chocolate flavour and reducing bitterness - then dried and roasted.[1]

Parts: Fruit, Seed
Season: As pods ripen, largely year-round in the tropics

Traditional Uses

Catnip has a long North American and European folk-medicine history as a mild sedative/nervine, diaphoretic (fever-reducing, sweat-promoting) remedy, carminative digestive and traditional emmenagogue; it was also given as a children's tea for colic and restlessness, though large amounts are not advised for young children and it is traditionally avoided in pregnancy.[9]

Cacao has an ancient Mesoamerican tradition (Maya and Aztec) as a ceremonial, medicinal and nutritive beverage, valued as a stimulant tonic and considered sacred - 'food of the gods', reflected in the genus name Theobroma. Modern research on its polyphenol (flavanol) content supports cardiovascular, antioxidant, anti-inflammatory and neuroprotective/cognitive benefits, particularly from minimally processed, high-flavanol cocoa.[1]

Preparations

Infusion (tea)[9]

Dried aerial parts steeped in hot water as a traditional calming, digestive tea.

Essential oil[6]

Steam-distilled from the aerial parts; used mainly as a natural insect repellent (nepetalactone) rather than taken internally.

Dark chocolate (high cocoa content)[1]

Minimally processed chocolate retaining more flavanols than milk chocolate.

Standardised flavanol extract (capsule)[2]

Concentrated extract used in some clinical cardiovascular research.

Dosage

Infusion (tea)[11]

Health Canada's NNHPD monograph gives 1.2-12 g of dried herb top per day for adults 18 years and older, with infusion among the accepted methods of preparation. Educational reference only, not a prescription. Keep away from toddlers and young children beyond very small amounts, and avoid medicinal-dose use in pregnancy.

Cocoa flavanol extract[2]

Large clinical trials of cocoa flavanol supplementation for cardiovascular prevention have used around 500 mg/day of cocoa flavanols. Educational reference only, not a prescription; treat concentrated cacao as a mild stimulant (theobromine, some caffeine) and moderate intake accordingly, especially in pregnancy, with heart-rhythm conditions, or on stimulant-sensitive medication.

References

REF-0930, REF-0931, REF-0932, REF-0933, REF-0934, REF-0935, REF-0936, REF-0937, REF-0938, REF-0939
REF-1084, REF-1085, REF-1086, REF-1087, REF-1088, REF-1089, REF-1090, REF-1091, REF-1092, REF-1093

Drug Class Interactions

Safety note[16, 17]Caution
Drug Class: sedatives-cns-depressants
Mechanism: Catnip is traditionally used as a calming, sedative herb; taken with sedatives, sleeping tablets or other central-nervous-system depressants (including alcohol) it may add to drowsiness and slowed reactions.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Not documented

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Geissler, M., Neubauer, C., Sheludko, Y.V. and Warzecha, H (2024) 'Nepeta cataria L. (catnip) can serve as a chassis for the engineering of secondary metabolic pathways', Biotechnology Letters, 46(5), pp. 843-850. doi:10.1007/s10529-024-03489-w Preclinical
    https://doi.org/10.1007/s10529-024-03489-w
  2. Lockhart, A., Simon, J.E. and Wu, Q (2024) 'Stability study of Nepeta cataria iridoids analyzed by LC/MS', Phytochemical Analysis, 35(7), pp. 1674-1687. doi:10.1002/pca.3410 Preclinical
    https://doi.org/10.1002/pca.3410
  3. Nadeem, A., Shahzad, H., Ahmed, B., Muntean, T. and others (2022) 'Phytochemical profiling of antimicrobial and potential antioxidant plant: Nepeta cataria', Frontiers in Plant Science, 13, pp. 969316. doi:10.3389/fpls.2022.969316 Preclinical
    https://doi.org/10.3389/fpls.2022.969316
  4. Tan, J., Li, J., Ma, J. and Qiao, F (2019) 'Hepatoprotective effect of essential oils of Nepeta cataria L. on acetaminophen-induced liver dysfunction', Bioscience Reports, 39(8), pp. BSR20190697. doi:10.1042/BSR20190697 Preclinical
    https://doi.org/10.1042/BSR20190697
  5. Mollova, S., Dzhurmanski, A., Fidan, H., Bojilov, D. and others (2023) 'Chemical Composition of Essential Oils from Nepeta cataria L. Cultivated in Bulgaria and Their Antimicrobial and Antioxidant Activity', ACS Omega, 8(17), pp. 15441-15449. doi:10.1021/acsomega.3c00704 Preclinical
    https://doi.org/10.1021/acsomega.3c00704
  6. Reichert, W., Ejercito, J., Guda, T., Dong, X. and others (2019) 'Repellency Assessment of Nepeta cataria Essential Oils and Isolated Nepetalactones on Aedes aegypti', Scientific Reports, 9(1), pp. 1524. doi:10.1038/s41598-018-36814-1 Preclinical
    https://doi.org/10.1038/s41598-018-36814-1
  7. Tiwari, G., Chaturvedi, T., Gupta, A.K., Lal, R.K. and others (2023) 'Assessment of Genetic Diversity, Micromorphology and Antimicrobial Activity in Nepeta cataria L', Chemistry & Biodiversity, 20(2), pp. e202200241. doi:10.1002/cbdv.202200241 Preclinical
    https://doi.org/10.1002/cbdv.202200241
  8. Giarratana, F., Muscolino, D., Ziino, G., Lo Presti, V. and others (2017) 'Activity of Catmint (Nepeta cataria) essential oil against Anisakis larvae', Tropical Biomedicine, 34(1), pp. 22-31. Available at: https://pubmed.ncbi.nlm.nih.gov/33592976/ Preclinical
    https://pubmed.ncbi.nlm.nih.gov/33592976/
  9. Sarkar, M., Rashmi, R., Vikramaditya and Varma, P.N (1995) 'Pharmacognosy of Nepeta cataria', Ancient Science of Life, 14(4), pp. 225-234. Available at: https://pubmed.ncbi.nlm.nih.gov/22556702/ Traditional / reference
    https://pubmed.ncbi.nlm.nih.gov/22556702/
  10. Bernardi, M.M., Kirsten, T.B., Lago, J.H.G., Giovani, T.M. and Massoco, C.O (2011) 'Nepeta cataria L. var. citriodora (Becker) increases penile erection in rats', Journal of Ethnopharmacology, 137(3), pp. 1318-1322. doi:10.1016/j.jep.2011.07.061 Preclinical
    https://doi.org/10.1016/j.jep.2011.07.061
  11. Health Canada, Natural and Non-prescription Health Products Directorate (2026) 'Natural Health Product Monograph: Catnip - Nepeta cataria'. Available at: https://webprod.hc-sc.gc.ca/nhpid-bdipsn/dbImages/mono_catnip_english.pdf Traditional / reference
    https://webprod.hc-sc.gc.ca/nhpid-bdipsn/dbImages/mono_catnip_english.pdf
  12. British Herbal Medicine Association (1983) 'British Herbal Pharmacopoeia'. Traditional / reference
    https://scholar.google.com/scholar?q=British%20Herbal%20Pharmacopoeia
  13. Gilani, A.H., Shah, A.J., Zubair, A., Khalid, S., Kiani, J., Ahmed, A., Rasheed, M. and Ahmad, V.U (2009) 'Chemical composition and mechanisms underlying the spasmolytic and bronchodilatory properties of the essential oil of Nepeta cataria L', 121(3), pp. 405--411. doi:10.1016/j.jep.2008.11.004 Traditional / reference
    https://doi.org/10.1016/j.jep.2008.11.004
  14. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
    https://powo.science.kew.org
  15. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  16. Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
    https://doi.org/10.1002/ptr.8201
  17. Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
    https://doi.org/10.1177/1534735404265003
  1. Tan, T.Y.C., Lim, X.Y., Yeo, J.H.H., Lee, S.W.H. and others (2021) 'The Health Effects of Chocolate and Cocoa: A Systematic Review', Nutrients, 13(9), pp. 2909. doi:10.3390/nu13092909 Meta-analysis / review
    https://doi.org/10.3390/nu13092909
  2. Sesso, H.D., Manson, J.E., Aragaki, A.K., Rist, P.M. and others (2022) 'Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial', The American Journal of Clinical Nutrition, 115(6), pp. 1490-1500. doi:10.1093/ajcn/nqac055 Randomized trial
    https://doi.org/10.1093/ajcn/nqac055
  3. Rimbach, G., Melchin, M., Moehring, J. and Wagner, A.E (2009) 'Polyphenols from cocoa and vascular health-a critical review', International Journal of Molecular Sciences, 10(10), pp. 4290-4309. doi:10.3390/ijms10104290 Meta-analysis / review
    https://doi.org/10.3390/ijms10104290
  4. Garcia, J.P., Santana, A., Baruqui, D.L. and Suraci, N (2018) 'The Cardiovascular effects of chocolate', Reviews in Cardiovascular Medicine, 19(4), pp. 123-127. doi:10.31083/j.rcm.2018.04.3187 Meta-analysis / review
    https://doi.org/10.31083/j.rcm.2018.04.3187
  5. Andujar, I., Recio, M.C., Giner, R.M. and Rios, J.L (2012) 'Cocoa polyphenols and their potential benefits for human health', Oxidative Medicine and Cellular Longevity, 2012, pp. 906252. doi:10.1155/2012/906252 Meta-analysis / review
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  7. Rusconi, M. and Conti, A (2010) 'Theobroma cacao L., the Food of the Gods: a scientific approach beyond myths and claims', Pharmacological Research, 61(1), pp. 5-13. doi:10.1016/j.phrs.2009.08.008 Meta-analysis / review
    https://doi.org/10.1016/j.phrs.2009.08.008
  8. Kang, H., Lee, C.H., Kim, J.R., Kwon, J.Y. and others (2017) 'Theobroma cacao extract attenuates the development of Dermatophagoides farinae-induced atopic dermatitis-like symptoms in NC/Nga mice', Food Chemistry, 216, pp. 19-26. doi:10.1016/j.foodchem.2016.07.141 Preclinical
    https://doi.org/10.1016/j.foodchem.2016.07.141
  9. Yasuda, A., Natsume, M., Osakabe, N., Kawahata, K. and others (2011) 'Cacao polyphenols influence the regulation of apolipoprotein in HepG2 and Caco2 cells', Journal of Agricultural and Food Chemistry, 59(4), pp. 1470-1476. doi:10.1021/jf103820b Preclinical
    https://doi.org/10.1021/jf103820b
  10. Visioli, F., Bernaert, H., Corti, R., Ferri, C. and others (2009) 'Chocolate, lifestyle, and health', Critical Reviews in Food Science and Nutrition, 49(4), pp. 299-312. doi:10.1080/10408390802066805 Meta-analysis / review
    https://doi.org/10.1080/10408390802066805
  11. Katz, D.L., Doughty, K. and Ali, A (2011) 'Cocoa and chocolate in human health and disease', 15(10), pp. 2779--2811. doi:10.1089/ars.2010.3697 Clinical study
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  12. Minifie, B.W (1989) 'Chocolate, Cocoa, and Confectionery: Science and Technology'. Traditional / reference
    https://scholar.google.com/scholar?q=Chocolate%2C%20Cocoa%2C%20and%20Confectionery%3A%20Science%20and%20Technology
  13. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
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  14. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.