Plant Comparison

Water avens vs Mallow

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant AWater avensGeum rivaleRosaceaeFull monograph →
Plant BMallowMalva sylvestrisMalvaceaeFull monograph →

At a glance

Water avens and Mallow: they share 6 indicated uses (cancer (anticancer research), sore throat, inflammation (general), …); 5 pharmacological actions in common.

Water avensMallow
Constituents74
Pharmacological actions108
Indicated uses913
Safety notes32
Cited sources1713
Indicated uses
Only Water avens
DiarrhoeaOral & throat healthBlood sugar / diabetes support
Shared (6)
Cancer (anticancer research)Sore throatInflammation (general)Infection (general)WoundsSkin irritation
Only Mallow
Arthritis / joint painBack painBruisingConstipationCoughHeadachePain (general)
Pharmacological actions
Only Water avens
AstringentAntidiarrhoealAntiviralNeuroprotective / cognition supportAntidiabetic (blood-sugar lowering)
Shared (5)
AntioxidantAntimicrobialAnti-inflammatoryAnticancer (preclinical)Vulnerary (wound healing)
Only Mallow
Analgesic (pain relief)Demulcent (soothing mucilage)Laxative

Evidence face-off — shared uses

ConditionWater avensMallowVerdict
Cancer (anticancer research)2/107/10Stronger for Mallow
Sore throat2/101/10Comparable evidence
Inflammation (general)2/102/10Comparable evidence
Infection (general)2/101/10Comparable evidence
Wounds2/105/10Stronger for Mallow
Skin irritation2/102/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Ellagitannins (pedunculagin, galloyl-bis-HHDP-hexose)[1, 6]

Hydrolysable ellagitannins - the dominant astringent constituents of water avens.

TanninsPhenolic compounds
Gallotannins and condensed tannins (proanthocyanidins)[1, 8]

Additional hydrolysable and condensed tannins contributing to the astringent, antidiarrhoeal and elastase-inhibiting activity.

TanninsProanthocyanidins
Ellagic acid and derivatives[1, 17]

Ellagic acid and ellagic-acid glycosides (antioxidant; precursors of anti-inflammatory urolithins in the gut).

Ellagic acidPhenolic acids
Gallic acid and derivatives[1, 2]

Gallic acid and galloyl derivatives (antioxidant, antimicrobial).

Gallic acidPhenolic acids
Flavonoids (quercetin, kaempferol, isorhamnetin glycosides)[1]

Antioxidant flavonol glycosides.

FlavonoidsQuercetinKaempferol
Triterpenoid saponins (niga-ichigoside)[2, 16]

Triterpenoid saponins and aglycones.

Triterpene saponinsSaponins
Essential oil - eugenol[5]

The root essential oil is dominated by eugenol, giving the clove-like scent (shared with clove) and antiseptic, mild-anaesthetic character.

Essential (volatile) oilEugenol
Mucilage polysaccharides[11]

The high mucilage content gives the demulcent, soothing action.

PolysaccharidesMucilage
Anthocyanins (malvin) and flavonoids[11, 12, 13]

The blue-purple pigments and antioxidant constituents.

AnthocyaninsFlavonoids
Coumarins and other phenolic compounds[12, 13]

Phenolic constituents associated with antioxidant and reported antiproliferative (anticancer) activity in cell studies.

Phenolic compoundsCoumarins
Tannins[11]

Mildly astringent constituents.

Tannins

Pharmacological Actions

Astringent[1, 6, 8]

Tannin-rich root, the basis of the traditional antidiarrhoeal and gargle uses.

Antidiarrhoeal[8, 9]

Astringent hydrolysable tannins; traditional remedy for diarrhoea and dysentery.

Antioxidant[1, 10, 15]
Antimicrobial[3, 11, 14, 15]
Anti-inflammatory[7, 17]

Inhibits prostaglandin biosynthesis; ellagitannin-derived urolithins are anti-inflammatory.

Anticancer (preclinical)[13, 14]

Geum (avens) extracts show antineoplastic and skin antineoplastic activity in vitro (preclinical).

Antiviral[13]

Antiviral activity of avens (Geum) extract in vitro (congener).

Neuroprotective / cognition support[1]

Neuroprotective activity of water avens polyphenol fractions.

Antidiabetic (blood-sugar lowering)[12]

Avens root extract showed antidiabetic (glucose-lowering) activity in vivo (congener G. urbanum).

Vulnerary (wound healing)[9, 14]

Astringent/antimicrobial root traditionally applied to wounds and inflamed skin; skin antineoplastic activity shown for avens.

Analgesic (pain relief)[8, 12, 13]

Anti-inflammatory, analgesic and wound-healing (preclinical)

Anti-inflammatory[2, 3, 6, 7, 9, 10, 12, 13]

Anti-inflammatory, analgesic and wound-healing (preclinical)

Anticancer (preclinical)[1]
Antimicrobial[12, 13]

Antibacterial / antimicrobial (methanolic leaf extracts; the naphthoquinone Malvone A)

Antioxidant[1, 4, 5, 9, 12, 13]

Antioxidant (phenolic compounds and anthocyanins)

Demulcent (soothing mucilage)[2, 11]

Demulcent for irritation of the mouth or throat and associated dry cough (soothing mucilage); Mild laxative for occasional constipation (mucilage; traditional)

Laxative[11]

Mild laxative for occasional constipation (mucilage; traditional)

Vulnerary (wound healing)[8, 9, 12, 13]

Anti-inflammatory, analgesic and wound-healing (preclinical)

Traditional & Indicated Uses

Cancer (anticancer research)[13, 14]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Diarrhoea[8, 9]Good · 7/10

Astringent (tannin) antidiarrhoeal; traditional remedy for diarrhoea and dysentery.

Evidence: 7
Label: Diarrhoea
Oral & throat health[9, 11]Traditional · 2/10

Root decoction used traditionally as a gargle/mouthwash for mouth ulcers and spongy gums; antimicrobial.

Evidence: 2
Label: Oral & throat health
Sore throat[3, 9]Traditional · 2/10

inferred from astringent/antimicrobial gargle use

Evidence: 2
Label: Sore throat
Inflammation (general)[7, 17]Traditional · 2/10
Evidence: 2
Label: Inflammation (general)
Infection (general)[3, 11]Traditional · 2/10

inferred from antimicrobial action

Evidence: 2
Label: Infection (general)
Wounds[9, 14]Traditional · 2/10

inferred from astringent/antimicrobial action and traditional wound-wash use

Evidence: 2
Label: Wounds
Skin irritation[14]Traditional · 2/10

inferred from anti-inflammatory/antimicrobial skin activity

Evidence: 2
Label: Skin irritation
Blood sugar / diabetes support[12]Traditional · 2/10

Avens root showed antidiabetic activity in vivo (congener).

Evidence: 2
Label: Blood sugar / diabetes support
Arthritis / joint pain[12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Back pain[12, 13]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Back pain
Bruising[12, 13]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Cancer (anticancer research)[1]Good · 7/10

inferred from anticancer action

Evidence: 7
Label: Cancer (anticancer research)
Constipation[11]Traditional · 1/10

Mild laxative for occasional constipation (mucilage; traditional)

Evidence: 1
Label: Constipation
Cough[11]Traditional · 1/10

Demulcent for irritation of the mouth or throat and associated dry cough (soothing mucilage)

Evidence: 1
Label: Cough
Headache[12, 13]Traditional · 1/10

inferred from analgesic action

Evidence: 1
Label: Headache
Infection (general)[12, 13]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[3, 6, 10, 12, 13]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Inflammation (general)
Pain (general)[8, 12, 13]Moderate · 5/10

inferred from analgesic action

Evidence: 5
Label: Pain (general)
Skin irritation[7, 11]Traditional · 2/10

Soothes irritated and inflamed skin and mucous membranes

Evidence: 2
Label: Skin irritation
Sore throat[11]Traditional · 1/10
Evidence: 1
Label: Sore throat
Wounds[8, 12, 13]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Wounds

Safety, Cautions & Contraindications

Safety note[1, 8]Caution

The root and herb are rich in tannins; large or prolonged doses may cause digestive upset or constipation and can reduce the absorption of iron and some medicines - take apart from iron supplements and other drugs.

Safety noteCaution

Safety in pregnancy and breastfeeding has not been established; avoid medicinal doses during pregnancy and lactation.

Safety note[13]Info

In-vivo toxicity testing of avens (Geum) extract showed a favourable profile at the doses studied, but high-dose or long-term safety is not established.

Safety note[11]Info

Generally very well tolerated. Irritation of the mouth/throat or a cough that persists beyond about a week, or is accompanied by fever or breathlessness, needs medical assessment.

Safety note[11]Caution

Use in pregnancy and breastfeeding is not recommended in the absence of adequate data.

External Ids

Gbif: 5369701
Powo: urn:lsid:ipni.org:names:725355-1
Wikidata: Q161625
Gbif: 3152374
Wikidata: Q156835

Synonyms

Geum rivale var. rivale

Not documented

Botanical Description

A perennial herb of the rose family, 20-60 cm tall, growing from a thick, reddish, aromatic rhizome that smells of cloves when broken (from its eugenol content) - the source of the name 'chocolate root'. The basal leaves are pinnate with a large terminal lobe, forming a rosette. Its distinctive flowers are nodding (drooping) bells with dull purple-pink to orange sepals and cream-to-pink petals, quite unlike the erect open yellow flowers of its relative wood avens (Geum urbanum). The fruit is a rounded head of achenes, each with a hooked, feathery style that clings to fur and clothing.[1, 9]

Height: 20-60 cm
Habit: Erect perennial herb from a thick aromatic rhizome
Leaves: Basal rosette of pinnate leaves with a large terminal lobe; stem leaves smaller, trifoliolate
Flowers: Nodding, bell-shaped, dull purple-pink to orange sepals with cream-to-pink petals (distinct from the erect yellow flowers of wood avens)
Stem: Erect, reddish, softly hairy
Root: Thick reddish rhizome smelling of cloves (eugenol) - the 'chocolate root'
Fruit: A rounded head of achenes, each with a hooked, feathery style
Flowering Period: May-September

Biennial or short-lived perennial herb, 30-120 cm tall, with erect or sprawling, branched, often reddish stems. Leaves are alternate, long-stalked and palmately lobed with 5-7 shallow rounded lobes and toothed margins. Flowers are pink-purple with darker veining, with five notch-tipped petals borne in small axillary clusters. The fruit is a flattened, disc-shaped schizocarp ('cheese') that splits into a ring of small single-seeded nutlets.[2]

Height: 30-120 cm
Habit: Erect to sprawling biennial/perennial herb
Leaves: Alternate, long-stalked, palmately 5-7-lobed with toothed margins
Flowers: Pink-purple with darker veins, five notched petals, in small axillary clusters
Stem: Erect or sprawling, branched, often reddish
Root: Taproot
Fruit: Flattened disc-shaped schizocarp ('cheese') of small nutlets
Flowering Period: June-September

Habitat

Damp ground: wet meadows, marshes, streamsides, ditches, fens and damp woodland across Europe, western Asia and North America. It favours moist, base-rich soils. Unlike wood avens (Geum urbanum), a plant of dry hedgerows and shade, water avens grows in wet, open places.[1]

Common on roadsides, waste ground, hedgebanks and field margins across Europe, North Africa and temperate Asia, and widely naturalised elsewhere; tolerates a wide range of soils, favouring sunny, disturbed, nitrogen-rich sites.[2]

Harvesting

The reddish rhizome/root is the main medicinal part, dug in spring or autumn and dried carefully to preserve its clove-scented, eugenol-bearing, tannin-rich qualities; the aerial flowering parts are gathered in summer. The root has historically been used both as an astringent medicine and as a flavouring (a coffee/chocolate substitute and to flavour ale).[5, 9]

Parts: Root, Rhizome, Aerial parts
Season: Root/rhizome in spring or autumn; aerial parts in flower (summer)

Leaves and flowers are gathered during the flowering period (summer) and dried quickly out of direct sun to preserve their mucilage content; fresh material can also be used directly for infusions or poultices.[11]

Parts: Leaf, Flower
Season: Summer, during flowering

Traditional Uses

Water avens shares the astringent, tannin-based traditional medicine of the avens (Geum) genus. The clove-scented root has been used as an astringent for diarrhoea, dysentery and other bowel complaints, as a gargle and mouth wash for sore throat, mouth ulcers and spongy gums, and as a wash for wounds and skin inflammation. It was also valued as an aromatic bitter tonic and, historically, a febrifuge, and the fragrant root was used to flavour ale and as a coffee/chocolate substitute (hence 'chocolate root').[8, 9]

Mallow leaf and flower have a long ethnobotanical history across Europe as a demulcent for irritated mucous membranes - soothing coughs, sore throat and mouth irritation - and for occasional constipation and skin irritation, reflecting the mucilage-rich leaf and flower. Modern phytochemical and pharmacological work confirms antioxidant, anti-inflammatory, antimicrobial and wound-healing activity of its extracts.[2, 11]

Preparations

Decoction[9]

The dried root/rhizome simmered in water as an astringent for diarrhoea and as a gargle for sore throat and inflamed gums.

Infusion[9]

The aerial parts or root infused as a milder astringent and aromatic tonic tea.

Gargle / mouthwash[9, 11]

A cooled root decoction used as a gargle/mouthwash for sore throat, mouth ulcers and spongy gums.

Infusion (hot)[11]

Dried leaf and/or flower steeped in hot water as a traditional soothing tea for cough, sore throat and mild digestive irritation.

Poultice/compress[7]

Crushed fresh or softened dried leaf applied externally to soothe irritated or inflamed skin.

References

REF-2761, REF-2762, REF-2763, REF-2764, REF-2765, REF-2766, REF-2767, REF-2768, REF-2769, REF-2770, REF-2771, REF-2772, REF-2773, REF-2774, REF-2775, REF-2776, REF-2777
REF-1183, REF-1184, REF-1185, REF-1186, REF-1187, REF-1188, REF-1189, REF-1190, REF-1191, REF-1192

Drug Class Interactions

Safety note[12]Caution
Drug Class: antidiabetics
Mechanism: Avens (Geum) root showed antidiabetic (glucose-lowering) activity; combined with antidiabetic medicines it could theoretically add to blood-sugar-lowering effects.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-10

Not documented

Pairings

Classic Rosaceae astringent pairing: both are tannin-rich roots traditionally combined for diarrhoea and as mouth/throat gargles.[8]

Partner Id: potentilla-erecta
Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-10

Rosaceae astringents rich in hydrolysable tannins, traditionally used together for diarrhoea, sore throat and as gargles.[8]

Partner Id: agrimonia-eupatoria
Type: synergy
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-10

Both are Rosaceae rich in ellagitannins and phenolics with overlapping antioxidant and anti-inflammatory profiles; water avens is astringent, meadowsweet more salicylate-based.[8, 10]

Partner Id: filipendula-ulmaria
Type: neutral
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-10

Not documented

Lookalikes Review

[9]

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-10
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Dosage

Not documented

Infusion[11]

EMA herbal-monograph guidance suggests roughly 1.5-2 g of dried leaf or flower per cup, taken as an infusion up to 3 times daily. Educational reference only, not a prescription.

References & Sources

  1. Orlova, A. and Kysil, E. and Tsvetkova, E. and Meshalkina, D. and Whaley, A. and Whaley, A.O. and Laub, A. and Francioso, A. and Babich, O. and Wessjohann, L.A. and Mosca, L. and Frolov, A. and Povydysh, M (2022) 'Phytochemical Characterization of Water Avens (Geum rivale L.) Extracts: Structure Assignment and Biological Activity of the Major Phenolic Constituents', Plants (Basel), 11(21), pp. 2859. doi:10.3390/plants11212859 Preclinical
    https://doi.org/10.3390/plants11212859
  2. Owczarek, A. and Gudej, J (2013) 'Investigation into biologically active constituents of Geum rivale L', Acta Poloniae Pharmaceutica, 70(1), pp. 111-114. Preclinical
    https://scholar.google.com/scholar?q=Investigation%20into%20biologically%20active%20constituents%20of%20Geum%20rivale%20L.
  3. Panizzi, L. and Catalano, S. and Miarelli, C. and Cioni, P.L. and Campeol, E (2000) 'In vitro antimicrobial activity of extracts and isolated constituents of Geum rivale', Phytotherapy Research, 14(7), pp. 561-563. doi:10.1002/1099-1573(200011)14:7<561::aid-ptr651>3.0.co;2-h Preclinical
    https://doi.org/10.1002/1099-1573(200011)14:7<561::aid-ptr651>3.0.co;2-h
  4. Ming, D. and Jiang, R. and But, P.P. and Towers, G.H.N. and Yu, D (2002) 'A new compound from Geum rivale L', Journal of Asian Natural Products Research, 4(3), pp. 217-220. doi:10.1080/10286020290024022 Preclinical
    https://doi.org/10.1080/10286020290024022
  5. Owczarek, A. and Gudej, J. and Kicel, A (2013) 'Composition of essential oil from aerial and underground parts of Geum rivale and G. urbanum growing in Poland', Natural Product Communications, 8(4), pp. 505-508. doi:10.1177/1934578x1300800425 Preclinical
    https://doi.org/10.1177/1934578x1300800425
  6. Bunse, M. and Lorenz, P. and Stintzing, F.C. and Kammerer, D.R (2021) 'Insight into the Secondary Metabolites of Geum rivale L. and Geum urbanum L. Seeds (Rosaceae)', Plants (Basel), 10(6), pp. 1219. doi:10.3390/plants10061219 Preclinical
    https://doi.org/10.3390/plants10061219
  7. Tunon, H. and Olavsdotter, C. and Bohlin, L (1995) 'Evaluation of anti-inflammatory activity of some Swedish medicinal plants. Inhibition of prostaglandin biosynthesis and PAF-induced exocytosis', Journal of Ethnopharmacology, 48(2), pp. 61-76. doi:10.1016/0378-8741(95)01285-l Preclinical
    https://doi.org/10.1016/0378-8741(95)01285-l
  8. Lamaison, J.L. and Carnat, A. and Petitjean-Freytet, C (1990) 'Tannin content and inhibiting activity of elastase in Rosaceae', Annales Pharmaceutiques Francaises, 48(6), pp. 335-340. Meta-analysis / review
    https://scholar.google.com/scholar?q=Tannin%20content%20and%20inhibiting%20activity%20of%20elastase%20in%20Rosaceae
  9. Blinova, K.F (1954) 'Anatomical structure of Geum urbanum and Geum rivale and localization of tannins', Aptechnoe Delo, 3(2), pp. 30-35. Traditional / reference
    https://scholar.google.com/scholar?q=Anatomical%20structure%20of%20Geum%20urbanum%20and%20Geum%20rivale%20and%20localization%20of%20tannins
  10. Kosmala, M. and Milala, J. and Karlinska, E (2025) 'Ellagitannins and Other Polyphenols Along with Dietary Components of the Rosaceae Medicinal Plants', Molecules, 30(23), pp. 4574. doi:10.3390/molecules30234574 Meta-analysis / review
    https://doi.org/10.3390/molecules30234574
  11. Bunse, M. and Mailander, L.K. and Lorenz, P. and Stintzing, F.C. and Kammerer, D.R (2022) 'Evaluation of Geum urbanum L. Extracts with Respect to Their Antimicrobial Potential', Chemistry and Biodiversity, 19(2), pp. e202100850. doi:10.1002/cbdv.202100850 Preclinical
    https://doi.org/10.1002/cbdv.202100850
  12. Gunther, I. and Rimbach, G. and Nevermann, S. and Neuhauser, C. and Stadlbauer, V. and Schwarzinger, B. and Schwarzinger, C. and Ipharraguerre, I.R. and Weghuber, J. and Luersen, K (2021) 'Avens Root (Geum urbanum L.) Extract Discovered by Target-Based Screening Exhibits Antidiabetic Activity in the Hen's Egg Test Model', Frontiers in Pharmacology, 12, pp. 794404. doi:10.3389/fphar.2021.794404 Preclinical
    https://doi.org/10.3389/fphar.2021.794404
  13. Zaharieva, M.M. and Dimitrova, L.L. and Philipov, S. and Nikolova, I. and Vilhelmova, N. and Grozdanov, P. and Nikolova, N. and Popova, M. and Bankova, V. and Konstantinov, S.M. and Zheleva-Dimitrova, D. and Najdenski, H.M (2021) 'In Vitro Antineoplastic and Antiviral Activity and In Vivo Toxicity of Geum urbanum L. Extracts', Molecules, 27(1), pp. 245. doi:10.3390/molecules27010245 Preclinical
    https://doi.org/10.3390/molecules27010245
  14. Dimitrova, L. and Zaharieva, M.M. and Tserovska, L. and Popova, M. and Bankova, V. and Najdenski, H (2025) 'Inhibition of the MRSA Biofilm Formation and Skin Antineoplastic Activity of Ethyl Acetate Roots and Aerial Parts Extracts from Geum urbanum L', Antibiotics (Basel), 14(7), pp. 627. doi:10.3390/antibiotics14070627 Preclinical
    https://doi.org/10.3390/antibiotics14070627
  15. Dimitrova, L. and Zaharieva, M.M. and Popova, M. and Kostadinova, N. and Tsvetkova, I. and Bankova, V. and Najdenski, H (2017) 'Antimicrobial and antioxidant potential of different solvent extracts of the medicinal plant Geum urbanum L', Chemistry Central Journal, 11(1), pp. 113. doi:10.1186/s13065-017-0343-8 Preclinical
    https://doi.org/10.1186/s13065-017-0343-8
  16. Ton That, Q. and Nguyen Thien, T.V. and Dang, H.P. and Le Hoan, N. and Vo, L.K.T. and Nguyen, M.H.D. and Ngu, N.T. and Nguyen, T.S. and Hansen, P.E (2018) 'Chemical constituents of Geum urbanum L. roots', Natural Product Research, 32(21), pp. 2529-2534. doi:10.1080/14786419.2018.1425844 Preclinical
    https://doi.org/10.1080/14786419.2018.1425844
  17. Piwowarski, J.P. and Granica, S. and Zwierzynska, M. and Stefanska, J. and Schopohl, P. and Melzig, M.F. and Kiss, A.K (2014) 'Role of human gut microbiota metabolism in the anti-inflammatory effect of traditionally used ellagitannin-rich plant materials', Journal of Ethnopharmacology, 155(1), pp. 801-809. doi:10.1016/j.jep.2014.06.032 Preclinical
    https://doi.org/10.1016/j.jep.2014.06.032
  1. Mousavi, S.M., Hashemi, S.A., Behbudi, G., Mazraedoost, S. and others (2021) 'A Review on Health Benefits of Malva sylvestris L. Nutritional Compounds for Metabolites, Antioxidants, and Anti-Inflammatory, Anticancer, and Antimicrobial Applications', Evidence-Based Complementary and Alternative Medicine, 2021, pp. 5548404. doi:10.1155/2021/5548404 Meta-analysis / review
    https://doi.org/10.1155/2021/5548404
  2. Gasparetto, J.C., Martins, C.A., Hayashi, S.S., Otuky, M.F. and others (2012) 'Ethnobotanical and scientific aspects of Malva sylvestris L.: a millennial herbal medicine', Journal of Pharmacy and Pharmacology, 64(2), pp. 172-189. doi:10.1111/j.2042-7158.2011.01383.x Meta-analysis / review
    https://doi.org/10.1111/j.2042-7158.2011.01383.x
  3. Wu, Y., Qiu, A., Yang, Z., Wu, J. and others (2019) 'Malva sylvestris extract alleviates the astrogliosis and inflammatory stress in LPS-induced depression mice', Journal of Neuroimmunology, 336, pp. 577029. doi:10.1016/j.jneuroim.2019.577029 Preclinical
    https://doi.org/10.1016/j.jneuroim.2019.577029
  4. Ben Saad, A., Rjeibi, I., Brahmi, D., Smida, A. and others (2016) 'Malva sylvestris extract protects upon lithium carbonate-induced kidney damages in male rat', Biomedicine & Pharmacotherapy, 84, pp. 1099-1107. doi:10.1016/j.biopha.2016.10.026 Preclinical
    https://doi.org/10.1016/j.biopha.2016.10.026
  5. Zuo, H., Li, Y., Cui, Y. and An, Y (2017) 'Cardioprotective effect of Malva sylvestris L. in myocardial ischemic/reperfused rats', Biomedicine & Pharmacotherapy, 95, pp. 679-684. doi:10.1016/j.biopha.2017.08.111 Preclinical
    https://doi.org/10.1016/j.biopha.2017.08.111
  6. Benso, B., Rosalen, P.L., Alencar, S.M. and Murata, R.M (2015) 'Malva sylvestris Inhibits Inflammatory Response in Oral Human Cells. An In Vitro Infection Model', PLoS One, 10(10), pp. e0140331. doi:10.1371/journal.pone.0140331 Preclinical
    https://doi.org/10.1371/journal.pone.0140331
  7. Prudente, A.S., Sponchiado, G., Mendes, D.A.G.B., Soley, B.S. and others (2017) 'Pre-clinical efficacy assessment of Malva sylvestris on chronic skin inflammation', Biomedicine & Pharmacotherapy, 93, pp. 852-860. doi:10.1016/j.biopha.2017.06.083 Preclinical
    https://doi.org/10.1016/j.biopha.2017.06.083
  8. Mohaghegh, Z., Golfakhrabadi, F., Faal Siahkal, S., Dastoorpoor, M. and others (2022) 'The Effect of Malva sylvestris Cream on Episiotomy Pain and Healing: A Randomized Controlled Clinical Trial', International Journal of Community Based Nursing and Midwifery, 10(4), pp. 248-258. doi:10.30476/IJCBNM.2022.95772.2082 Randomized trial
    https://doi.org/10.30476/IJCBNM.2022.95772.2082
  9. Areesanan, A., Nicolay, S., Keller, M., Zimmermann-Klemd, A.M. and others (2023) 'Potential benefits of Malva sylvestris in dry-eye disease pathology in vitro based on antioxidant, wound-healing and anti-inflammatory properties', Biomedicine & Pharmacotherapy, 168, pp. 115782. doi:10.1016/j.biopha.2023.115782 Preclinical
    https://doi.org/10.1016/j.biopha.2023.115782
  10. Martins, C.A., Weffort-Santos, A.M., Gasparetto, J.C., Trindade, A.C. and others (2014) 'Malva sylvestris L. extract suppresses desferrioxamine-induced PGE2 and PGD2 release in differentiated U937 cells', Biomedical Chromatography, 28(7), pp. 986-993. doi:10.1002/bmc.3106 Preclinical
    https://doi.org/10.1002/bmc.3106
  11. European Medicines Agency (HMPC) (n.d.) 'European Union herbal monograph on Malva sylvestris L., folium and flos (Malvae folium / Malvae sylvestris flos)'. Available at: https://www.ema.europa.eu/en/medicines/herbal/malvae-folium Traditional / reference
    https://www.ema.europa.eu/en/medicines/herbal/malvae-folium
  12. Paul, Z.A. and Malla, A.T. and Dar, M.A. and Masoodi, M.H (2024) 'Phytochemistry and Pharmacological Activity of Malva sylvestris L.: A Detailed Insight', Combinatorial Chemistry & High Throughput Screening, 27(16), pp. 2309--2322. doi:10.2174/0113862073269336231009110313 Traditional / reference
    https://doi.org/10.2174/0113862073269336231009110313
  13. Batiha, G.E. and Tene, S.T. and Teibo, J.O. and Shaheen, H.M. and Oluwatoba, O.S. and Teibo, T.K.A. and Al-Kuraishy, H.M. and Al-Garbee, A.I. and Alexiou, A. and Papadakis, M (2022) 'The phytochemical profiling, pharmacological activities, and safety of Malva sylvestris: a review', Naunyn-Schmiedeberg's Archives of Pharmacology, 396(3), pp. 421--440. doi:10.1007/s00210-022-02329-w Traditional / reference
    https://doi.org/10.1007/s00210-022-02329-w

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.