Plant Comparison
Meadowsweet vs Cranberry
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Meadowsweet and Cranberry: they share 6 indicated uses (arthritis / joint pain, infection (general), inflammation (general), …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Meadowsweet | Cranberry | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Infection (general) | 1/10 | 2/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 2/10 | Comparable evidence |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
| Urinary support | 1/10 | 5/10 | Stronger for Cranberry |
| Wounds | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Historically the source of aspirin's chemical inspiration; provide the plant's analgesic and anti-inflammatory activity, buffered by co-occurring mucilage and tannins.
Antioxidant constituents contributing to the plant's anti-inflammatory and gastroprotective effects.
Contribute to astringency and the characteristic sweet almond-like fragrance.
The A-type proanthocyanidins are considered responsible for inhibiting bacterial adhesion to the urinary tract lining.
Give the fruit its characteristic tartness and are traditionally credited with a mild urinary-acidifying effect.
Pharmacological Actions
Traditional & Indicated Uses
inferred from gastroprotective action
inferred from anti-inflammatory action
inferred from anticancer action
inferred from gastroprotective action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
inferred from anti-inflammatory action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
Generally safe in normal culinary and medicinal doses. Avoid in salicylate sensitivity or aspirin allergy. Not recommended for children with viral illnesses (Reye's syndrome risk, as with other salicylate-containing plants). Avoid during pregnancy and breastfeeding.
Duke (2002) rates meadowsweet as ++ and notes analgesic, antiulcer, antirheumatic, astringent, and anti-aggregant activities at the experimental level (score 1). The plant is historically significant as a precursor to aspirin — salicylate compounds in meadowsweet were originally used to derive acetylsalicylic acid. Unlike aspirin, meadowsweet's salicylates are combined with protective mucilaginous compounds that may reduce gastric irritation. Duke notes that individuals with aspirin (salicylate) sensitivity should avoid meadowsweet; the plant also has anticoagulant properties that may interact with blood-thinning medications (Duke, 2002).
Food amounts are generally considered safe (berries in meals, drinks, sauces). (Williams et al., 2023).
Duke (2002) includes cranberry primarily at the experimental level for its astringent, diuretic, and antioxidant properties. Commission E has not approved cranberry for specific indications, though there is evidence supporting its role in preventing urinary tract infections (UTIs) by inhibiting bacterial adhesion to uroepithelial cells (proanthocyanidins). Duke notes the high vitamin C and organic acid content. Food-grade consumption is considered safe and beneficial as a urinary acidifier (Duke, 2002).
External Ids
Botanical Description
Tall, moisture-loving perennial herb with pinnately compound leaves, dark green above and whitish-downy beneath, the leaflets sharply toothed. Dense, fluffy, creamy-white flower clusters with a strong, sweet, almond-like fragrance are borne atop reddish, grooved stems.[1]
Low, creeping, evergreen dwarf shrub (Ericaceae) with slender, wiry stems that root at the nodes. Leaves are tiny, alternate, leathery and ovate with in-rolled margins, dark green above and whitish beneath. Flowers are small, pink and four-petalled, sharply reflexed backward so that the protruding stamens and style resemble a crane's head and neck - the origin of the name 'craneberry', later shortened to 'cranberry'. The fruit is a small, round, tart red berry.[8]
Habitat
Grows in damp meadows, marshes, riverbanks, ditches and wet woodland margins; native to Europe and temperate Asia, favouring moist, nutrient-rich ground.[1]
Native to boggy, acidic wetlands - sphagnum bogs and marshes - across northern and central Europe and northern Asia, requiring waterlogged, nutrient-poor, acidic peat soils.[8]
Harvesting
The flowering tops, leaf and stem are cut in summer as the flowers open, when the characteristic salicylate content is highest, and dried in a warm, shaded, airy place.[1]
Berries are hand-picked or wet-harvested (traditionally by hand-raking the bog) in autumn once fully ripe and deep red.[8]
Traditional Uses
Meadowsweet is historically significant as the plant from which salicylic acid derivatives (the chemical basis of aspirin) were first isolated, and has long been used in European folk medicine as an anti-inflammatory, analgesic and gastroprotective remedy for feverish colds, rheumatic and joint pain, and digestive complaints such as acid reflux and indigestion - notably, its natural mucilage is thought to buffer the gastric irritation associated with isolated salicylates.[1, 4]
Cranberry has a long northern-European and Native American tradition as a food and folk remedy for urinary complaints, valued for its tart, astringent, vitamin-C-rich fruit. Modern research on its proanthocyanidins supports a role in reducing bacterial adhesion in the urinary tract, consistent with the traditional use for cystitis and recurrent urinary tract infections.[2, 11]
Preparations
Dried flower, leaf and stem infused in hot water as a traditional anti-inflammatory and digestive tea.
Tincture (1:5) of the dried aerial parts; single dose 2-4 ml, daily dose 6-12 ml per the EU herbal monograph. Educational reference only, not a prescription.
Concentrated extract studied in vitro and in vivo for anti-inflammatory and gastroprotective activity.
Dosage
The EU herbal monograph gives a single dose of 1.5-6 g of the comminuted herb as an infusion, for a daily dose of 2-18 g, in adults and elderly; a powdered herbal substance at 250-500 mg per dose (250-1500 mg daily) and a 1:5 tincture at 2-4 mL per dose (6-12 mL daily) are also listed. Contraindicated in hypersensitivity to salicylates. For rheumatic-type complaints, not to be used for more than 4 weeks. Not recommended under 18 years. Educational reference only, not a prescription.
Not documented
References
Lookalikes Review
References & Sources
- Samardžić, S., Arsenijević, J., Božić, D., Milenković, M. et al (2017) 'Antioxidant, anti-inflammatory and gastroprotective activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench', Journal of Ethnopharmacology, 213, pp. 132-137. doi:10.1016/j.jep.2017.11.013 Preclinical
https://doi.org/10.1016/j.jep.2017.11.013 - Andonova, T., Muhovski, Y., Apostolova, E., Naimov, S. et al (2024) 'DNA-Protective, Antioxidant and Anti-Carcinogenic Potential of Meadowsweet (Filipendula ulmaria) Dry Tincture', Antioxidants (Basel), 13(10), pp. 1200. doi:10.3390/antiox13101200 Preclinical
https://doi.org/10.3390/antiox13101200 - Van der Auwera, A., Peeters, L., Foubert, K., Piazza, S. et al (2023) 'In Vitro Biotransformation and Anti-Inflammatory Activity of Constituents and Metabolites of Filipendula ulmaria', Pharmaceutics, 15(4), pp. 1291. doi:10.3390/pharmaceutics15041291 Preclinical
https://doi.org/10.3390/pharmaceutics15041291 - Katanic, J., Boroja, T., Mihailovic, V., Nikles, S., Pan, S., Rosic, G., Selakovic, D., Joksimovic, J., Mitrovic, S. and Bauer, R (2016) 'In vitro and in vivo assessment of meadowsweet (Filipendula ulmaria) as anti-inflammatory agent', Journal of Ethnopharmacology, 193, pp. 627-636. doi:10.1016/j.jep.2016.10.015 Preclinical
https://doi.org/10.1016/j.jep.2016.10.015 - Samardzic, S., Tomic, M., Pecikoza, U., Stepanovic-Petrovic, R. and Maksimovic, Z (2016) 'Antihyperalgesic activity of Filipendula ulmaria (L.) Maxim. and Filipendula vulgaris Moench in a rat model of inflammation', Journal of Ethnopharmacology, 193, pp. 652-656. doi:10.1016/j.jep.2016.10.024 Preclinical
https://doi.org/10.1016/j.jep.2016.10.024 - Katanic, J., Matic, S., Pferschy-Wenzig, E., Kretschmer, N., Boroja, T., Mihailovic, V., Stankovic, V., Stankovic, N., Mladenovic, M., Stanic, S., Mihailovic, M. and Bauer, R (2016) 'Filipendula ulmaria extracts attenuate cisplatin-induced liver and kidney oxidative stress in rats: In vivo investigation and LC-MS analysis', Food and Chemical Toxicology, 99, pp. 86-102. doi:10.1016/j.fct.2016.11.018 Preclinical
https://doi.org/10.1016/j.fct.2016.11.018 - Arsenijevic, N., Selakovic, D., Katanic Stankovic, J.S., Mihailovic, V., Mitrovic, S., Milenkovic, J., Milanovic, P., Vasovic, M., Nikezic, A., Milosevic-Djordjevic, O., Zivanovic, M., Filipovic, N., Jakovljevic, V., Jovicic, N. and Rosic, G (2021) 'Variable neuroprotective role of Filipendula ulmaria extract in rat hippocampus', Journal of Integrative Neuroscience, 20(4), pp. 871-883. doi:10.31083/j.jin2004089 Preclinical
https://doi.org/10.31083/j.jin2004089 - Matic, S., Katanic, J., Stanic, S., Mladenovic, M., Stankovic, N., Mihailovic, V. and Boroja, T (2015) 'In vitro and in vivo assessment of the genotoxicity and antigenotoxicity of the Filipendula hexapetala and Filipendula ulmaria methanol extracts', Journal of Ethnopharmacology, 174, pp. 287-292. doi:10.1016/j.jep.2015.08.025 Preclinical
https://doi.org/10.1016/j.jep.2015.08.025 - Pannakal, S.T., Eilstein, J., Hubert, J., Kotland, A., Prasad, A., Gueguiniat-Prevot, A., Juchaux, F., Beaumard, F., Seru, G., John, S. and Roy, D (2023) 'Rapid Chemical Profiling of Filipendula ulmaria Using CPC Fractionation, 2-D Mapping of 13C NMR Data, and High-Resolution LC-MS', Molecules, 28(17), pp. 6349. doi:10.3390/molecules28176349 Preclinical
https://doi.org/10.3390/molecules28176349 - Valle, M.G., Nano, G.M. and Tira, S (1988) 'The Essential Oil of Filipendula ulmaria', Planta Medica, 54(2), pp. 181-182. doi:10.1055/s-2006-962390 Preclinical
https://doi.org/10.1055/s-2006-962390 - Popowski, D., Zentek, J., Piwowarski, J.P. and Granica, S (2021) 'Gut Microbiota of Pigs Metabolizes Extracts of Filipendula ulmaria and Orthosiphon aristatus - Herbal Remedies Used in Urinary Tract Disorders', Planta Medica, 88(3-04), pp. 254-261. doi:10.1055/a-1647-2866 Preclinical
https://doi.org/10.1055/a-1647-2866 - Bespalov, V.G., Alexandrov, V.A., Semenov, A.L., Kovan'ko, E.G., Ivanov, S.D., Vysochina, G.I., Kostikova, V.A. and Baranenko, D.A (2016) 'The inhibitory effect of meadowsweet (Filipendula ulmaria) on radiation-induced carcinogenesis in rats', International Journal of Radiation Biology, 93(4), pp. 394-401. doi:10.1080/09553002.2016.1257834 Preclinical
https://doi.org/10.1080/09553002.2016.1257834 - European Medicines Agency (HMPC) (2011) 'Community herbal monograph on Filipendula ulmaria (L.) Maxim., herba'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-filipendula-ulmaria-l-maxim-herba-first-version_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-filipendula-ulmaria-l-maxim-herba-first-version_en.pdf - Bridge, J (2008) 'The Herbal Remedy Handbook'. Traditional / reference
https://scholar.google.com/scholar?q=The%20Herbal%20Remedy%20Handbook - Drummond, E.M., Harbourne, N., Marete, E., Jacquier, J.C., O'Riordan, D. and Gibney, E.R (2013) 'Inhibition of pro-inflammatory biomarkers in THP1 macrophages by polyphenols derived from chamomile, meadowsweet and willow bark', 27(4), pp. 588--594. Traditional / reference
https://scholar.google.com/scholar?q=Inhibition%20of%20pro-inflammatory%20biomarkers%20in%20THP1%20macrophages%20by%20polyphenols%20derived%20from%20chamomile%2C%20meadowsweet%20and%20willow%20bark - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
- Shareef, S.M., Khaleel, R.A. and Maryoosh, T.M (2024) 'Nephroprotective effect of cranberry (Vaccinium oxycoccos) in streptozocin-induced diabetic nephropathy in mice', Drug Metabolism and Personalized Therapy, 39(1), pp. 35-45. doi:10.1515/dmpt-2023-0092 Preclinical
https://doi.org/10.1515/dmpt-2023-0092 - Jurikova, T., Skrovankova, S., Mlcek, J., Balla, S. and Snopek, L (2018) 'Bioactive Compounds, Antioxidant Activity, and Biological Effects of European Cranberry (Vaccinium oxycoccos)', Molecules, 24(1), pp. 24. doi:10.3390/molecules24010024 Traditional / reference
https://doi.org/10.3390/molecules24010024 - Sedbare, R., Raudone, L., Zvikas, V., Viskelis, J. and others (2022) 'Development and Validation of the UPLC-DAD Methodology for the Detection of Triterpenoids and Phytosterols in Fruit Samples of Vaccinium macrocarpon Aiton and Vaccinium oxycoccos L', Molecules, 27(14), pp. 4403. doi:10.3390/molecules27144403 Preclinical
https://doi.org/10.3390/molecules27144403 - Sedbare, R., Sprainaityte, S., Baublys, G., Viskelis, J. and Janulis, V (2023) 'Phytochemical Composition of Cranberry (Vaccinium oxycoccos L.) Fruits Growing in Protected Areas of Lithuania', Plants (Basel), 12(10), pp. 1974. doi:10.3390/plants12101974 Preclinical
https://doi.org/10.3390/plants12101974 - Brown, P.N., Turi, C.E., Shipley, P.R. and Murch, S.J (2012) 'Comparisons of large (Vaccinium macrocarpon Ait.) and small (Vaccinium oxycoccos L., Vaccinium vitis-idaea L.) cranberry in British Columbia by phytochemical determination, antioxidant potential, and metabolomic profiling with chemometric analysis', Planta Medica, 78(6), pp. 630-640. doi:10.1055/s-0031-1298239 Preclinical
https://doi.org/10.1055/s-0031-1298239 - Harini, K., Janani, K., Teja, K.V., Mohan, C. and Sukumar, M (2022) 'Formulation and evaluation of oral disintegrating films using a natural ingredient against Streptococcus mutans', Journal of Conservative Dentistry, 25(2), pp. 128-134. doi:10.4103/jcd.jcd_143_21 Preclinical
https://doi.org/10.4103/jcd.jcd_143_21 - Cesoniene, L., Daubaras, R., Jasutiene, I., Vencloviene, J. and Miliauskiene, I (2011) 'Evaluation of the biochemical components and chromatic properties of the juice of Vaccinium macrocarpon Aiton and Vaccinium oxycoccos L', Plant Foods for Human Nutrition, 66(3), pp. 238-244. doi:10.1007/s11130-011-0241-5 Preclinical
https://doi.org/10.1007/s11130-011-0241-5 - Van Rossum, F., Vereecken, N.J., Bredat, E. and Michez, D (2012) 'Pollen dispersal and fruit production in Vaccinium oxycoccos and comparison with its sympatric congener V. uliginosum', Plant Biology, 15(2), pp. 344-352. doi:10.1111/j.1438-8677.2012.00646.x Preclinical
https://doi.org/10.1111/j.1438-8677.2012.00646.x - Kawash, J., Colt, K., Hartwick, N.T., Abramson, B.W. and others (2022) 'Contrasting a reference cranberry genome to a crop wild relative provides insights into adaptation, domestication, and breeding', PLoS One, 17(3), pp. e0264966. doi:10.1371/journal.pone.0264966 Preclinical
https://doi.org/10.1371/journal.pone.0264966 - Stobnicka, A. and Gniewosz, M (2017) 'Antimicrobial protection of minced pork meat with the use of Swamp Cranberry (Vaccinium oxycoccos L.) fruit and pomace extracts', Journal of Food Science and Technology, 55(1), pp. 62-71. doi:10.1007/s13197-017-2770-x Preclinical
https://doi.org/10.1007/s13197-017-2770-x - Hooton, T.M., Vecchio, M., Iroz, A., Tack, I., Dornic, Q., Seksek, I. and Lotan, Y (2018) 'Effect of increased daily water intake in premenopausal women with recurrent urinary tract infections: a randomized clinical trial', 178(11), pp. 1509--1515. doi:10.1001/jamainternmed.2018.4204 Randomized trial
https://doi.org/10.1001/jamainternmed.2018.4204 - Jepson, R.G., Williams, G. and Craig, J.C (2012) 'Cranberries for preventing urinary tract infections'. Traditional / reference
https://scholar.google.com/scholar?q=Cranberries%20for%20preventing%20urinary%20tract%20infections - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.