Plant Comparison
Eyebright vs Tormentil
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Eyebright and Tormentil: they share 5 indicated uses (arthritis / joint pain, diarrhoea, inflammation (general), …); 2 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Eyebright | Tormentil | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Diarrhoea | 1/10 | 5/10 | Stronger for Tormentil |
| Inflammation (general) | 2/10 | 3/10 | Comparable evidence |
| Skin irritation | 1/10 | 6/10 | Stronger for Tormentil |
| Wounds | 1/10 | 5/10 | Stronger for Tormentil |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Give the plant its anti-inflammatory action on irritated tissue.
Pharmacological Actions
Astringent and anti-inflammatory for eye irritation, redness and conjunctivitis (traditional, as an eye compress or bath) - an open prospective cohort of Euphrasia single-dose eye drops reported recovery or clear improvement in most patients with conjunctivitis
Anti-inflammatory gargle / mouthwash for sore throat and inflammation of the mouth and throat
Astringent for mild diarrhoea (ellagitannins tighten the gut lining) - in a paediatric RCT, tormentil root extract shortened rotavirus diarrhoea (3 vs 5 days) and reduced rehydration needs
Traditional & Indicated Uses
Eases eye strain and watery, itchy eyes from allergy (hay fever / allergic conjunctivitis)
inferred from anti-inflammatory action
inferred from anticancer action
Soothes upper-respiratory catarrh and mild infection (traditional)
Astringent and anti-inflammatory for eye irritation, redness and conjunctivitis (traditional, as an eye compress or bath) - an open prospective cohort of Euphrasia single-dose eye drops reported recovery or clear improvement in most patients with conjunctivitis; Eases eye strain and watery, itchy eyes from allergy (hay fever / allergic conjunctivitis)
Eases eye strain and watery, itchy eyes from allergy (hay fever / allergic conjunctivitis)
Soothes upper-respiratory catarrh and mild infection (traditional)
inferred from anti-inflammatory action
Soothes upper-respiratory catarrh and mild infection (traditional)
inferred from anti-inflammatory action
inferred from anti-inflammatory action
Astringent for mild diarrhoea (ellagitannins tighten the gut lining) - in a paediatric RCT, tormentil root extract shortened rotavirus diarrhoea (3 vs 5 days) and reduced rehydration needs
Supportive in inflammatory bowel disease / ulcerative colitis (limited trial evidence)
Anti-inflammatory gargle / mouthwash for sore throat and inflammation of the mouth and throat
inferred from astringent action
Anti-inflammatory gargle / mouthwash for sore throat and inflammation of the mouth and throat
Safety, Cautions & Contraindications
CRITICAL: do not put non-sterile, homemade eyebright preparations directly into the eye - this risks serious eye infection. Use only commercially prepared sterile products in the eye, or apply a strained, cooled infusion as a compress over closed eyelids.
Traditional use only; persistent eye symptoms, pain, discharge or vision change need assessment by an eye-care professional. Safety in pregnancy and breastfeeding is not established.
Tannin-rich: high or prolonged intake may cause stomach upset or constipation and can reduce the absorption of iron and some medicines taken at the same time.
Diarrhoea persisting more than 3-4 days, or with fever or blood in the stool, needs medical care. Use in pregnancy and breastfeeding is not recommended in the absence of data.
External Ids
Botanical Description
Small, semi-parasitic annual herb (drawing some nutrients from the roots of neighbouring grasses) with tiny, opposite, toothed leaves and delicate, two-lipped white to pale lilac flowers marked with purple veins and a yellow throat spot, giving a bright, eye-like appearance that inspired both its common and Latin names.[11]
Low, sprawling to semi-erect perennial herb (Rosaceae) with wiry stems. Leaves are palmate, typically with 4-5 leaflets and large leaf-like stipules that give the impression of more leaflets. Flowers are small, yellow and four-petalled - unusual among Potentilla species, most of which have five petals. The thick, woody rhizome is reddish inside when cut, the origin of the old name 'bloodroot' for this European species.[14]
Habitat
Grows in short, unimproved grassland, pastures, meadows and dunes on well-drained soils, always in association with grasses on which it partially parasitises; native to Europe.[11]
Native to Europe and western Asia, common in acidic grassland, heath, moorland, open woodland and pastures on poor, well-drained soils.[14]
Harvesting
The flowering aerial parts are cut in summer while in flower and dried in a warm, shaded, airy place.[11]
The rhizome is dug in autumn or early spring, when tannin content is highest, then cleaned and dried.[14]
Traditional Uses
Tormentil rhizome has an official European herbal-monograph tradition for mild diarrhoea and inflammation of the mouth and throat, reflecting its long folk use as a powerful astringent for gut and mucous-membrane complaints. Modern trials confirm its ellagitannin-rich rhizome shortens the duration of infectious (rotavirus) diarrhoea.[8, 14, 15]
Preparations
Strained, cooled infusion applied as a compress over closed eyelids, or used (only when sterile, commercially prepared) as an eyewash for irritated or red eyes.
Commercially prepared, sterile Euphrasia eye drops used for conjunctivitis; a prospective clinical cohort found improvement in most users.
Dosage
No dose is given here because no official posology exists. The HMPC assessed eyebright and DECLINED to establish a herbal monograph, concluding that the efficacy of the claimed uses is undocumented and that external eye application of ex tempore (home-prepared) preparations is 'not hygienic and not safe', so therapeutic use cannot be recommended. Traditional sources describe a strained, cooled infusion used as a compress, but that is precisely the practice the HMPC advised against; nothing home-prepared should be put in or on the eye. Educational reference only, not a prescription.
References
Lookalikes Review
References & Sources
- Novy, P., Davidova, H., Serrano-Rojero, C.S., Rondevaldova, J. et al (2015) 'Composition and Antimicrobial Activity of Euphrasia rostkoviana Hayne Essential Oil', Evidence-Based Complementary and Alternative Medicine, 2015, pp. 734101. doi:10.1155/2015/734101 Preclinical
https://doi.org/10.1155/2015/734101 - D'Ambrosio, M., Ciocarlan, A. and Aricu, A (2020) 'Minor acetylated metabolites from Euphrasia rostkoviana', Natural Product Research, 34(2), pp. 290-295. doi:10.1080/14786419.2018.1530227 Preclinical
https://doi.org/10.1080/14786419.2018.1530227 - Ververis, A., Kyriakou, S., Paraskeva, H., Panayiotidis, M.I. et al (2024) 'Chemical Characterization and Assessment of the Neuroprotective Potential of Euphrasia officinalis', International Journal of Molecular Sciences, 25(23), pp. 12902. doi:10.3390/ijms252312902 Preclinical
https://doi.org/10.3390/ijms252312902 - Meier-Girard, D., Gerstenberg, G., Stoffel, L., Kohler, T., Klein, S.D., Eschenmoser, M., Mitter, V.R., Nelle, M. and Wolf, U (2020) 'Euphrasia eye drops in preterm neonates with ocular discharge: a randomized double-blind placebo-controlled trial', Frontiers in Pediatrics, 8, pp. 449. doi:10.3389/fped.2020.00449 Randomized trial
https://doi.org/10.3389/fped.2020.00449 - Liu, Y., Hwang, E., Ngo, H.T.T., Perumalsamy, H., Kim, Y.J., Li, L. and Yi, T.H (2018) 'Protective effects of Euphrasia officinalis extract against ultraviolet B-induced photoaging in normal human dermal fibroblasts', International Journal of Molecular Sciences, 19(11), pp. 3327. doi:10.3390/ijms19113327 Preclinical
https://doi.org/10.3390/ijms19113327 - Porchezhian, E., Ansari, S.H. and Shreedharan, N.K (2000) 'Antihyperglycemic activity of Euphrasia officinale leaves', Fitoterapia, 71(5), pp. 522-526. doi:10.1016/s0367-326x(00)00204-5 Preclinical
https://doi.org/10.1016/s0367-326x(00)00204-5 - Sticher, O. and Salama, O (1981) 'Iridoid glucosides from Euphrasia rostkoviana', Planta Medica, 42(6), pp. 122-123. doi:10.1055/s-2007-971584 Preclinical
https://doi.org/10.1055/s-2007-971584 - Lorenz, P., Knittel, D.N., Conrad, J., Lotter, E.M., Heilmann, J., Stintzing, F.C. and Kammerer, D.R (2016) '1-Acetyl-3-[(3R)-hydroxyfatty acyl]glycerols: lipid compounds from Euphrasia rostkoviana Hayne and E. tetraquetra (Breb.) Arrond', Chemistry & Biodiversity, 13(5), pp. 602-612. doi:10.1002/cbdv.201500233 Preclinical
https://doi.org/10.1002/cbdv.201500233 - Gawenda-Kempczynska, D., Olech, M., Balcerek, M., Nowak, R., Zaluski, T. and Zaluski, D (2022) 'Phenolic acids as chemotaxonomic markers able to differentiate the Euphrasia species', Phytochemistry, 203, pp. 113342. doi:10.1016/j.phytochem.2022.113342 Preclinical
https://doi.org/10.1016/j.phytochem.2022.113342 - Benedec, D., Oniga, I., Hanganu, D., Vlase, A.M., Ielciu, I., Crisan, G., Fit, N., Niculae, M., Bab, T., Pall, E. and Vlase, L (2024) 'Revealing the Phenolic Composition and the Antioxidant, Antimicrobial and Antiproliferative Activities of Two Euphrasia sp. Extracts', Plants, 13(13), pp. 1790. doi:10.3390/plants13131790 Preclinical
https://doi.org/10.3390/plants13131790 - Herbal Reality (n.d.) 'Eyebright (Euphrasia officinalis): Benefits, Uses, Safety'. Available at: https://www.herbalreality.com/herb/eyebright/ Traditional / reference
https://www.herbalreality.com/herb/eyebright/ - Paduch, R. and colleagues (2014) 'Assessment of Eyebright (Euphrasia officinalis L.) Extract Activity in Relation to Human Corneal Cells Using In Vitro Tests'. doi:10.5152/balkanmedj.2014.8377 Traditional / reference
https://doi.org/10.5152/balkanmedj.2014.8377 - Stoss, M., Michels, C., Peter, E., Beutke, R. and Gorter, R.W (2000) 'Prospective cohort trial of Euphrasia single-dose eye drops in conjunctivitis', Journal of Alternative and Complementary Medicine, 6(6), pp. 499--508. doi:10.1089/acm.2000.6.499 Clinical study
https://doi.org/10.1089/acm.2000.6.499 - European Medicines Agency (HMPC) (2010) 'Public statement on Euphrasia officinalis L. and Euphrasia rostkoviana Hayne, herba'. Available at: https://www.ema.europa.eu/en/documents/herbal-report/final-public-statement-euphrasia-officinalis-l-and-euphrasia-rostkoviana-hayne-herba_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-report/final-public-statement-euphrasia-officinalis-l-and-euphrasia-rostkoviana-hayne-herba_en.pdf
- Bandick, R., Busmann, L.V., Mousavi, S., Shayya, N.W. and others (2023) 'Therapeutic Effects of Oral Application of Menthol and Extracts from Tormentil (Potentilla erecta), Raspberry Leaves and Loosestrife during Acute Murine Campylobacteriosis', Pharmaceutics, 15(10), pp. 2410. doi:10.3390/pharmaceutics15102410 Preclinical
https://doi.org/10.3390/pharmaceutics15102410 - Fecka, I., Kucharska, A.Z. and Kowalczyk, A (2015) 'Quantification of tannins and related polyphenols in commercial products of tormentil (Potentilla tormentilla)', Phytochemical Analysis, 26(5), pp. 353-366. doi:10.1002/pca.2570 Preclinical
https://doi.org/10.1002/pca.2570 - Marcinczyk, N., Jarmoc, D., Leszczynska, A., Zakrzeska, A. and others (2017) 'Antithrombotic Potential of Tormentil Extract in Animal Models', Frontiers in Pharmacology, 8, pp. 534. doi:10.3389/fphar.2017.00534 Preclinical
https://doi.org/10.3389/fphar.2017.00534 - Melzig, M.F. and Bottger, S (2020) 'Tormentillae rhizoma - Review for an Underestimated European Herbal Drug', Planta Medica, 86(15), pp. 1050-1057. doi:10.1055/a-1129-7214 Traditional / reference
https://doi.org/10.1055/a-1129-7214 - Marcinczyk, N., Golaszewska, A., Gromotowicz-Poplawska, A., Misztal, T. and others (2021) 'Multidirectional Effects of Tormentil Extract on Hemostasis in Experimental Diabetes', Frontiers in Pharmacology, 12, pp. 682987. doi:10.3389/fphar.2021.682987 Preclinical
https://doi.org/10.3389/fphar.2021.682987 - Hoffmann, J., Gendrisch, F., Schempp, C.M. and Wolfle, U (2020) 'New Herbal Biomedicines for the Topical Treatment of Dermatological Disorders', Biomedicines, 8(2), pp. 27. doi:10.3390/biomedicines8020027 Traditional / reference
https://doi.org/10.3390/biomedicines8020027 - Tomczyk, M., Sosnowska, K., Pleszczynska, M., Strawa, J. and others (2017) 'Hydrogel Containing an Extract of Tormentillae rhizoma for the Treatment of Biofilm-Related Oral Diseases', Natural Product Communications, 12(3), pp. 417-421. doi:10.1177/1934578x1701200328 Preclinical
https://doi.org/10.1177/1934578x1701200328 - Subbotina, M.D., Timchenko, V.N., Vorobyov, M.M., Konunova, Y.S., Aleksandrovih, Y.S. and Shushunov, S (2003) 'Effect of oral administration of tormentil root extract (Potentilla tormentilla) on rotavirus diarrhea in children: a randomized, double blind, controlled trial', The Pediatric Infectious Disease Journal, 22(8), pp. 706--711. doi:10.1097/01.inf.0000078355.29647.d0 Randomized trial
https://doi.org/10.1097/01.inf.0000078355.29647.d0 - Wan, P., Chen, H., Guo, Y. and Bai, A.P (2014) 'Advances in treatment of ulcerative colitis with herbs: from bench to bedside', World Journal of Gastroenterology, 20(39), pp. 14099-14104. doi:10.3748/wjg.v20.i39.14099 Traditional / reference
https://doi.org/10.3748/wjg.v20.i39.14099 - Wolfle, U., Hoffmann, J., Haarhaus, B., Rao Mittapalli, V. and Schempp, C.M (2017) 'Anti-inflammatory and vasoconstrictive properties of Potentilla erecta - A traditional medicinal plant from the northern hemisphere', Journal of Ethnopharmacology, 204, pp. 86-94. doi:10.1016/j.jep.2017.03.058 Clinical study
https://doi.org/10.1016/j.jep.2017.03.058 - Moss, A.C. and Cheifetz, A.S (2007) 'Reducing the torment of diarrhea: tormentil for active ulcerative colitis', Journal of Clinical Gastroenterology, 41(9), pp. 797-798. doi:10.1097/MCG.0b013e3180684255 Clinical study
https://doi.org/10.1097/MCG.0b013e3180684255 - Shushunov, S., Balashov, L., Kravtsova, A., Krasnogorsky, I., Latte, K.P. and Vasiliev, A (2009) 'Determination of acute toxicity of the aqueous extract of Potentilla erecta (Tormentil) rhizomes in rats and mice', Journal of Medicinal Food, 12(5), pp. 1173-1176. doi:10.1089/jmf.2008.0281 Preclinical
https://doi.org/10.1089/jmf.2008.0281 - Kirsch, J., Jung, A., Hille, K., Konig, B., Hannig, C., Kolling-Speer, I., Speer, K. and Hannig, M (2020) 'Effect of fragaria vesca, hamamelis and tormentil on the initial bacterial colonization in situ', Archives of Oral Biology, 118, pp. 104853. doi:10.1016/j.archoralbio.2020.104853 Preclinical
https://doi.org/10.1016/j.archoralbio.2020.104853 - European Medicines Agency (HMPC) (n.d.) 'European Union herbal monograph on Potentilla erecta (L.) Raeusch., rhizoma (Tormentillae rhizoma)'. Available at: https://www.ema.europa.eu/en/medicines/herbal/tormentillae-rhizoma Traditional / reference
https://www.ema.europa.eu/en/medicines/herbal/tormentillae-rhizoma - ESCOP (European Scientific Cooperative on Phytotherapy) (n.d.) 'Tormentillae rhizoma (Tormentil) monograph', pp. com. Available at: https://www.escop.com/downloads/tormentil/ Traditional / reference
https://www.escop.com/downloads/tormentil/
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.