Plant Comparison

Field Horsetail vs White clover

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant AField HorsetailEquisetum arvenseEquisetaceaeFull monograph →
Plant BWhite cloverTrifolium repensFabaceaeFull monograph →

At a glance

Field Horsetail and White clover: they share 7 indicated uses (arthritis / joint pain, bruising, cancer (anticancer research), …); 4 pharmacological actions in common.

Field HorsetailWhite clover
Constituents33
Pharmacological actions611
Indicated uses1115
Safety notes22
Cited sources1933
Indicated uses
Only Field Horsetail
Back painSwelling / fluid retentionUrinary supportUrinary tract infection (UTI)
Shared (7)
Arthritis / joint painBruisingCancer (anticancer research)Infection (general)Inflammation (general)Skin irritationWounds
Only White clover
Cold & fluImmune supportMenstrual crampsMuscle spasmKidney supportLiver supportBlood sugar / diabetes supportCognitive function
Pharmacological actions
Only Field Horsetail
Anti-rheumatic / anti-arthriticDiuretic
Shared (4)
Anti-inflammatoryAnticancer (preclinical)AntimicrobialVulnerary (wound healing)
Only White clover
AntioxidantAntispasmodicImmunomodulator / immune supportNephroprotective (kidney support)Hepatoprotective (liver support)Antidiabetic (blood-sugar lowering)Neuroprotective / cognition support

Evidence face-off — shared uses

ConditionField HorsetailWhite cloverVerdict
Arthritis / joint pain5/101/10Stronger for Field Horsetail
Bruising5/101/10Stronger for Field Horsetail
Cancer (anticancer research)2/102/10Comparable evidence
Infection (general)5/102/10Stronger for Field Horsetail
Inflammation (general)5/102/10Stronger for Field Horsetail
Skin irritation5/101/10Stronger for Field Horsetail
Wounds5/107/10Stronger for White clover

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Silica (silicic acid)[11]

Field horsetail is exceptionally rich in silica, concentrated in the stem, and is a signature source of this mineral in Western herbal medicine.

Silica
Flavonoids[11]

Antioxidant flavonoids contributing to the plant's anti-inflammatory activity.

Flavonoids
Thiaminase[11]

An enzyme that degrades vitamin B1 (thiamine); the basis of the caution against prolonged or excessive use.

Isoflavones[32]

Phytoestrogenic isoflavones, present at lower levels than in red clover.

Flavonoids
Cyanogenic glycosides (trace)[30]

Present in small amounts; not significant in normal food or tea use.

Glycosides
Phenolic acids and flavonoids[32]

Contribute to antioxidant activity.

Phenolic acidsFlavonoids

Pharmacological Actions

Anti-inflammatory[2, 3, 5, 11, 12, 13, 14, 15]
Anti-rheumatic / anti-arthritic[2, 11, 12, 13, 14, 15]
Anticancer (preclinical)[4]
Antimicrobial[11, 12, 13, 14, 15]
Diuretic[11, 12, 13, 14, 15]
Vulnerary (wound healing)[11, 12, 13, 14, 15]
Anti-inflammatory[1, 2, 5, 6, 22, 28, 30, 31, 32]
Antioxidant[1, 2, 4, 5, 7, 8, 9, 10, 14, 16, 17, 20, 21, 23, 24, 25, 28, 30, 31, 32]
Antispasmodic[30, 31, 32]

Antispasmodic (cramp easing)

Immunomodulator / immune support[2, 30, 31, 32]
Vulnerary (wound healing)[1, 7, 13, 30, 31, 32]
Nephroprotective (kidney support)[4]
Anticancer (preclinical)[3, 10]
Hepatoprotective (liver support)[9]
Antimicrobial[12, 18, 22, 26, 28]
Antidiabetic (blood-sugar lowering)[10, 20]
Neuroprotective / cognition support[22, 23]

Traditional & Indicated Uses

Arthritis / joint pain[2, 11, 12, 13, 14, 15]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Arthritis / joint pain
Back pain[11, 12, 13, 14, 15]Moderate · 5/10

inferred from anti-rheumatic action

Evidence: 5
Label: Back pain
Bruising[11, 12, 13, 14, 15]Moderate · 5/10

inferred from vulnerary action

Evidence: 5
Label: Bruising
Cancer (anticancer research)[4]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Infection (general)[11, 12, 13, 14, 15]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Infection (general)
Inflammation (general)[3, 11, 12, 13, 14, 15]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Inflammation (general)
Skin irritation[11, 12, 13, 14, 15]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Skin irritation
Swelling / fluid retention[11, 12, 13, 14, 15]Moderate · 5/10

inferred from diuretic action

Evidence: 5
Label: Swelling / fluid retention
Urinary support[11, 12, 13, 14, 15]Moderate · 5/10

inferred from diuretic action

Evidence: 5
Label: Urinary support
Urinary tract infection (UTI)[11, 12, 13, 14, 15]Moderate · 5/10

inferred from diuretic action

Evidence: 5
Label: Urinary tract infection (UTI)
Wounds[11, 12, 13, 14, 15]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Wounds
Arthritis / joint pain[30, 31, 32]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bruising[30, 31, 32]Traditional · 1/10

inferred from vulnerary action

Evidence: 1
Label: Bruising
Cancer (anticancer research)[3, 10]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Cold & flu[30, 31, 32]Traditional · 1/10

inferred from immunomodulator action

Evidence: 1
Label: Cold & flu
Immune support[30, 31, 32]Traditional · 1/10
Evidence: 1
Label: Immune support
Inflammation (general)[6, 30, 31, 32]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Inflammation (general)
Menstrual cramps[30, 31, 32]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Menstrual cramps
Muscle spasm[30, 31, 32]Traditional · 1/10

inferred from antispasmodic action

Evidence: 1
Label: Muscle spasm
Skin irritation[30, 31, 32]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[1, 7, 13, 30, 31, 32]Good · 7/10

inferred from vulnerary action

Evidence: 7
Label: Wounds
Kidney support[4]Traditional · 2/10
Evidence: 2
Label: Kidney support
Liver support[9]Traditional · 2/10
Evidence: 2
Label: Liver support
Blood sugar / diabetes support[10, 20]Traditional · 2/10
Evidence: 2
Label: Blood sugar / diabetes support
Infection (general)[12, 18, 22, 26]Traditional · 2/10

inferred from antimicrobial action

Evidence: 2
Label: Infection (general)
Cognitive function[22, 23]Traditional · 2/10
Evidence: 2
Label: Cognitive function

Safety, Cautions & Contraindications

Safety note[11, 12, 13, 14, 15]Caution

Field horsetail contains thiaminase, an enzyme that degrades thiamine (vitamin B1); prolonged or excessive use can cause thiamine deficiency — symptoms include neurological problems and weight loss. This risk is greatest with repeated large doses or prolonged use. The plant also contains nicotine at low levels and silica compounds. Not recommended for children or during pregnancy and breastfeeding. People with impaired kidney function should avoid use, as diuretic effects may worsen fluid and electrolyte imbalance. Caution with concurrent diuretic medications. The EMA herbal monograph recognises traditional use at appropriate short-term doses in adults only (European Medicines Agency, 2016; Sandhu et al., 2010).

Safety note[11, 12, 13, 14, 15, 16]Caution

Duke (2002) rates horsetail as + (moderate caution) and notes clinical evidence (score 2) for its diuretic and wound-healing (vulnerary) activities, consistent with Commission E approval. High silica content may strengthen connective tissue, hair, and nails. Dose: 6 g dried herb daily as tea or in capsules. Horsetail contains thiaminase (breaks down vitamin B1) and an unidentified neurotoxin — it should not be taken long-term or in large quantities. Not for use in patients with edema due to cardiac or renal insufficiency, and avoid in children under 12 (Duke, 2002).

Safety note[30, 31, 32]Caution

Generally very safe as a food and in moderate herbal use. Cyanogenic glucosides present in very small amounts — not significant in normal food or tea use. Isoflavones are phytoestrogens (as in red clover) — same precautions apply in hormone-sensitive conditions. Well tolerated by most people.

Safety note[30, 31, 32, 33]Info

Duke (2002) does not include a dedicated entry for white clover (Trifolium repens) in the Handbook of Medicinal Herbs, Second Edition.

External Ids

Gbif: 7924597
Wikidata: Q107592
Gbif: 5358748
Wikidata: Q148675

Botanical Description

Perennial, spore-bearing (non-flowering) plant with two distinct stem types arising from a deep, black, jointed rhizome. In early spring, unbranched, pale brownish fertile stems appear first, each topped with a spore-bearing cone, and die back once spores are shed; these are followed by the familiar green, hollow, jointed, ridged sterile stems bearing whorls of thin, needle-like branches at each node, giving a bottlebrush appearance.

Height: 20-80 cm (sterile stems)
Habit: Perennial, spore-bearing (non-flowering) herb with separate fertile and sterile stems
Leaves: Reduced to small, fused, toothed sheaths at each stem node (true leaves absent)
Flowers: None; reproduces by spores borne in a cone atop the unbranched fertile spring stems
Stem: Hollow, jointed, ridged green sterile stems with whorled branches; separate pale unbranched fertile stems in spring
Root: Deep, black, jointed, far-spreading rhizome
Fruit: Spores released from the fertile cone, not a true fruit
Flowering Period: Not applicable (spore-bearing); fertile stems appear in early spring

Low, creeping perennial herb rooting at the nodes, with trifoliate leaves, each leaflet oval and often marked with a pale chevron. Rounded white (sometimes pink-tinged) flower heads are borne on long stalks above the foliage.[30]

Height: 5-15 cm (creeping, flower stalks slightly taller)
Habit: Low, creeping, mat-forming perennial herb
Leaves: Trifoliate, each leaflet oval, often marked with a pale chevron
Flowers: Rounded white (sometimes pink-tinged) heads of small pea-like flowers on long stalks
Stem: Creeping, rooting at the nodes
Root: Fibrous roots with nitrogen-fixing nodules
Fruit: Small pod containing 3-4 seeds
Flowering Period: May-October

Habitat

Grows in damp grassland, waste ground, riverbanks, roadsides and disturbed soil on a wide range of soils; native and common across the temperate Northern Hemisphere (Europe, Asia, North America).

Grows in lawns, pastures, meadows and grassy waste ground; native to Europe and western Asia and now naturalised worldwide, including as a common lawn and forage plant.[30]

Harvesting

The green sterile stems are cut in summer, at their most vigorous, and dried quickly in a warm, shaded, airy place; careful identification against the more toxic marsh horsetail (Equisetum palustre), which grows in similar damp ground, is essential before wild-harvesting.

Parts: Stem, Whole Plant
Season: Summer, when sterile stems are fully grown

Flowering heads and leaves are picked through the flowering season and dried in a warm, shaded, airy place.[30]

Parts: Flower, Leaf
Season: May-October

Traditional Uses

Field horsetail has a long European folk history as a diuretic remedy for urinary gravel and mild fluid retention, as an astringent, anti-inflammatory and vulnerary herb for wounds and connective-tissue support, and, owing to its very high silica content, as a traditional tonic for hair, nails and skin.[11]

White clover has a folk tradition, similar to but lighter than its relative red clover, as an anti-inflammatory and wound-healing remedy and mild expectorant, and modern research on its isoflavones and phenolics has additionally investigated antioxidant, kidney-protective and liver-protective activity.[30, 31, 32]

Preparations

Decoction/infusion[11]

Dried sterile stem simmered or infused in hot water as a traditional diuretic and connective-tissue-support tea.

Infusion (flower/leaf)[30]

Dried flower and leaf infused in hot water as a traditional mild tonic and expectorant tea.

Dosage

Decoction/infusion[12]

The EU herbal monograph gives a single dose of 1-4 g of the comminuted herb in 150 mL of boiling water as an infusion or decoction (5-15 minutes), 3-4 times daily, for a daily dose of 3-12 g, in adolescents, adults and elderly; traditionally used over a period of 2 to 4 weeks. For cutaneous use, 10 g in 1 L of water as a decoction for impregnated dressings and irrigation. Not recommended under 12 years. Educational reference only, not a prescription.

Not documented

References

REF-1398, REF-0727, REF-1399, REF-1400, REF-1401, REF-1402, REF-1403, REF-1404, REF-1405, REF-1406
REF-1323, REF-1324, REF-1325, REF-1326, REF-1327, REF-2366, REF-2367, REF-2368, REF-2369, REF-2901, REF-2902, REF-2903, REF-2904, REF-2905, REF-2906, REF-2907, REF-2908, REF-2909, REF-2910, REF-2935, REF-2936, REF-2937, REF-2938, REF-2939, REF-2940, REF-2941, REF-2942, REF-2943, REF-2944

Lookalikes Review

Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Dangerous Lookalikes

Safety note[17, 18, 19]Dangerous
Dangerous Plant: equisetum-palustre
Confused Part: Sterile green stems gathered and dried for horsetail tea; toxic marsh horsetail looks very similar and grows in the same damp ground.
Confusion Context: Field horsetail (Equisetum arvense) is gathered for horsetail tea, but horsetails are notoriously hard to tell apart, and marsh horsetail (Equisetum palustre) - one of the most poisonous plants of wet grasslands - grows in the same damp habitat and looks very similar. Marsh horsetail contains the alkaloids palustrine and palustridiene plus high thiaminase (which destroys vitamin B1); it is a well-known livestock poison, and peer-reviewed work stresses that medicinal horsetail must be properly authenticated and differentiated from the more toxic marsh horsetail, which can adulterate herbal material. Because the species are so alike, unverified wild horsetail is a real hazard.
Distinguishing Features: Branch teeth: marsh horsetail (the toxic one) has 5-6 teeth on each branch sheath that lie flat (appressed) against the branch. Broad, spreading teeth in threes or fours indicate a non-toxic horsetail rather than marsh horsetail., Branches solid vs hollow: marsh horsetail has hollow branches, whereas field horsetail's branches are solid. A hollow first branch segment is a warning sign., First branch segment vs sheath: on marsh horsetail the lowest segment of each side branch is short - shorter than or about equal to the stem sheath it emerges from. A first branch segment clearly longer than the sheath indicates it is NOT marsh horsetail. Marsh horsetail also favours wet, marshy ground and fens.
Key Test: Because horsetails are so alike and marsh horsetail is poisonous, only use wild horsetail if you can positively exclude marsh horsetail (Equisetum palustre): confirm branch sheaths have 3-4 spreading teeth (not 5-6 flat-lying ones), solid (not hollow) branches, and a first branch segment longer than the stem sheath. If you cannot confirm all of these - or the plant grows in wet, marshy ground - do not use it.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Not documented

References & Sources

  1. Hegedus, C., Muresan, M., Badale, A., Bombicz, M. and others (2020) 'SIRT1 Activation by Equisetum arvense L. (Horsetail) Modulates Insulin Sensitivity in Streptozotocin Induced Diabetic Rats', Molecules, 25(11), pp. 2541. doi:10.3390/molecules25112541 Preclinical
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  10. Tufarelli, V., Baghban-Kanani, P., Azimi-Youvalari, S., Hosseintabar-Ghasemabad, B. and others (2021) 'Effects of Horsetail (Equisetum arvense) and Spirulina (Spirulina platensis) Dietary Supplementation on Laying Hens Productivity and Oxidative Status', Animals, 11(2), pp. 335. doi:10.3390/ani11020335 Preclinical
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  11. Carneiro, D.M., Marques, L.C., Velasques, L.O. et al (2016) 'Randomized, double-blind clinical trial to assess the acute diuretic effect of Equisetum arvense (Field Horsetail) in healthy volunteers'. doi:10.1155/2014/760683 Randomized trial
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  12. European Medicines Agency (2016) 'European Union herbal monograph on Equisetum arvense L., herba'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-equisetum-arvense-l-herba_en.pdf Traditional / reference
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  13. http://LatvijasDaba.lv (n.d.) 'tīruma kosa – Equisetum arvense L'. Available at: http://LatvijasDaba.lv Traditional / reference
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  17. NatureSpot 'Marsh Horsetail - Equisetum palustre'. Available at: https://www.naturespot.org/species/marsh-horsetail Traditional / reference
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  1. Ngangom, L., Venugopal, D. and Pandey, N (2024) 'Investigation of Trifolium repens L. from the Indian Himalayan region as a phyto-therapeutic agent', Natural Product Research, 38(24), pp. 4468-4478. doi:10.1080/14786419.2023.2299319 Meta-analysis / review
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    https://doi.org/10.3390/cells9020379
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  7. Habibi Zadeh, S.K., Farahpour, M.R. and Kar, H.H (2020) 'The effect of topical administration of an ointment prepared from Trifolium repens hydroethanolic extract on the acceleration of excisional cutaneous wound healing', Wounds, 32(9), pp. 253-261. doi:10.25270/wnds/2020.253261 Preclinical
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  9. Ahmad, S. and Zeb, A (2019) 'Effects of phenolic compounds from aqueous extract of Trifolium repens against acetaminophen-induced hepatotoxicity in mice', Journal of Food Biochemistry, 43(9), pp. e12963. doi:10.1111/jfbc.12963 Preclinical
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  10. Borczak, B. and Szewczyk, A. and Domagała, D. and Kapusta-Duch, J. and Leszczyńska, T. and Kotuła, M. and Grulova, D (2024) 'Potential Antidiabetic, Antioxidative and Antiproliferative Properties of Functional Wheat Flour Muffins Enriched with White Clover Flowers (Trifolium repens L.)', Int J Mol Sci, 25(18). doi:10.3390/ijms25189909 Preclinical
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  11. Rawat, P. and Kumar, B. and Misra, A. and Singh, S.P. and Singh, S.P. and Srivastava, S (2025) 'Effect of hydrolysed Trifolium repens L. extract on menopause-induced obesity and depressive symptoms: an in vitro and in vivo approach', Nat Prod Res, pp. 1-8. doi:10.1080/14786419.2025.2560636 Preclinical
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  12. Parić, A. and Mesic, A. and Mahmutović-Dizdarević, I. and Jerković-Mujkić, A. and Žujo, B. and Bašić, N. and Pustahija, F (2024) 'Bioactive potential of Trifolium repens L. essential oil', J Environ Sci Health B, 59(9), pp. 584-594. doi:10.1080/03601234.2024.2396730 Preclinical
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.