Plant Comparison
Purple coneflower vs Scots Pine
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Purple coneflower and Scots Pine: they share 5 indicated uses (arthritis / joint pain, infection (general), inflammation (general), …); 2 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Purple coneflower | Scots Pine | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 2/10 | Comparable evidence |
| Infection (general) | 1/10 | 2/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 2/10 | Comparable evidence |
| Skin irritation | 1/10 | 2/10 | Comparable evidence |
| Wounds | 1/10 | 2/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Lipophilic alkamides are considered key immunomodulatory and anti-inflammatory constituents, particularly concentrated in the root.
Antioxidant phenolic compounds contributing to the plant's immunomodulatory activity.
Water-soluble polysaccharides associated with immune-stimulating activity, particularly from the aerial parts.
The needle oil is dominated by monoterpene hydrocarbons, chiefly alpha-pinene, giving the characteristic resinous scent and much of its antimicrobial activity.
The resinous sap/pitch, traditionally used topically for wounds and skin complaints.
The needle is traditionally valued as a source of vitamin C, particularly in winter.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from immunomodulator action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from expectorant action
inferred from anticancer action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
Safety, Cautions & Contraindications
Generally considered safe, but caution advised for those with autoimmune conditions. Not recommended for long-term use (more than 8 weeks continuously).
Duke (2002) rates echinacea as +++ — among the most thoroughly documented herbal immunostimulants. It notes experimental and clinical evidence for immunostimulant, antiviral, and anti-inflammatory activities. Multiple species have been studied (E. purpurea, E. angustifolia, E. pallida), and Duke emphasizes that species identification in commercial products is often unreliable. Commission E approves E. purpurea for supporting immune function during colds and flu. Dose: 900 mg standardized extract daily in acute use; use should be limited to 8 weeks continuous. Contraindicated in autoimmune diseases (MS, lupus, HIV/AIDS), tuberculosis, and with immunosuppressive drugs (cyclosporine) (Duke, 2002).
Generally safe in normal amounts. Pine essential oil should not be ingested; topical use only in diluted form. May irritate airways in high concentrations. Allergic reactions to pine pollen and resin are common. Turpentine products are irritant and potentially toxic if ingested.
Duke (2002) rates Scotch pine as + and notes antiseptic, antibacterial (score 1), and bronchospasmolytic activities. Commission E (KOM) and PhEur (PIP) approve pine needle preparations for topical use in rheumatic and neuralgic conditions and for inhalations in upper respiratory catarrh. Duke cautions that pine needle oil should not be inhaled by patients with severe asthma, whooping cough, or laryngospasm. Pine bud preparations are traditionally used for bronchitis and sinus congestion. Dose: 100–200 mg essential oil in ointment or cream for topical use (Duke, 2002).
External Ids
Botanical Description
Robust perennial herb with a basal rosette of coarse, hairy, lance-shaped leaves and tall, sturdy flowering stems. Each stem bears a single large, daisy-like flower head with drooping (reflexed), rose-purple to pink ray florets surrounding a prominent, spiny, orange-brown central cone of disc florets.[4]
Evergreen coniferous tree (Pinaceae), 15-35 m tall, with a long, straight trunk at maturity, distinctive orange-red flaking bark in the upper crown and grey-brown fissured bark at the base. Needles are blue-green, borne in pairs (fascicles of two) with a papery basal sheath. Small yellow male cones release pollen in spring; female cones are woody and mature over two years.[11]
Habitat
Native to the tallgrass prairies, open woodland and dry meadows of central and eastern North America; widely cultivated worldwide as a garden and medicinal plant.[4]
Native across northern and central Europe and Siberia - the most widely distributed pine species in the world - forming extensive boreal and montane forests on poor, sandy or peaty, acidic soils; a pioneer species tolerant of dry, nutrient-poor ground.[11]
Harvesting
The flower heads are picked as they open, in summer; the root is dug in autumn from plants at least two to three years old, when its content of bioactive alkamides and caffeic acid derivatives is highest, then cleaned and dried.[4]
Young shoots ('candles') and needles are gathered in spring; bark is stripped from felled or cultivated trees; resin/sap is tapped from the trunk. Needle-bearing twigs can be cut for tea and for steam distillation of the essential oil year-round.[11]
Traditional Uses
Echinacea root was widely used by Native American peoples as a remedy for infections, wounds, snakebite and toothache, and entered nineteenth-century Eclectic medicine as a broad anti-infective. It remains best known today, in standardised aerial-part or root extracts, as a supportive remedy for preventing and shortening the common cold and supporting immune function.[1, 4]
Scots pine has a long northern European tradition as a source of resinous, aromatic preparations for respiratory complaints (coughs, bronchitis, catarrh) and topical rheumatic/muscular remedies, and pine-needle tea has traditionally been valued as a vitamin-C-rich winter tonic. Modern research on the needle essential oil supports antimicrobial, anti-inflammatory and expectorant activity.[11, 12]
Preparations
Fresh-pressed juice or standardised extract of the aerial parts or root, taken as tablets, drops or capsules at the first sign of a cold; the best-studied clinical form.
Fresh or dried young needles steeped in hot water - the traditional vitamin-C-rich tonic tea. Only use needles from a certainly identified pine, never yew (see dangerous look-alikes).
Steam-distilled from the needles; used diluted in ointments, chest rubs or steam inhalation for respiratory complaints.
Dosage
Clinical trials for the common cold commonly use around 300-900 mg of standardised extract daily, started at the first sign of symptoms and continued for up to 7-10 days; continuous use beyond about 8 weeks is not recommended. Educational reference only, not a prescription.
References
Drug Class Interactions
Not documented
Lookalikes Review
Dangerous Lookalikes
Not documented
References & Sources
- Karsch-Völk, M., Barrett, B., Kiefer, D., Bauer, R. et al (2014) 'Echinacea for preventing and treating the common cold', Cochrane Database of Systematic Reviews, 2(2), pp. CD000530. doi:10.1002/14651858.CD000530.pub3 Meta-analysis / review
https://doi.org/10.1002/14651858.CD000530.pub3 - Kamin, W., Seifert, G., Zwiauer, K., Bonhoeffer, J. et al (2025) 'Phytotherapy for acute respiratory tract infections in children: a systematically conducted, comprehensive review', Frontiers in Pediatrics, 13, pp. 1423250. doi:10.3389/fped.2025.1423250 Meta-analysis / review
https://doi.org/10.3389/fped.2025.1423250 - Fashner, J., Ericson, K. and Werner, S (2012) 'Treatment of the common cold in children and adults', American Family Physician, 86(2), pp. 153-159. Available at: https://pubmed.ncbi.nlm.nih.gov/22962927/ Traditional / reference
https://pubmed.ncbi.nlm.nih.gov/22962927/ - Manayi, A., Vazirian, M. and Saeidnia, S (2015) 'Echinacea purpurea: Pharmacology, phytochemistry and analysis methods', Pharmacognosy Reviews, 9(17), pp. 63-72. doi:10.4103/0973-7847.156353 Meta-analysis / review
https://doi.org/10.4103/0973-7847.156353 - Burlou-Nagy, C., Banica, F., Jurca, T., Vicas, L.G., Marian, E., Muresan, M.E., Bacskay, I., Kiss, R., Feher, P. and Pallag, A (2022) 'Echinacea purpurea (L.) Moench: Biological and Pharmacological Properties. A Review', Plants, 11(9), pp. 1244. doi:10.3390/plants11091244 Meta-analysis / review
https://doi.org/10.3390/plants11091244 - Hall, H., Fahlman, M.M. and Engels, H.J (2007) 'Echinacea purpurea and mucosal immunity', International Journal of Sports Medicine, 28(9), pp. 792-797. doi:10.1055/s-2007-964895 Randomized trial
https://doi.org/10.1055/s-2007-964895 - Ross, S.M (2016) 'Echinacea purpurea: A Proprietary Extract of Echinacea purpurea Is Shown to be Safe and Effective in the Prevention of the Common Cold', Holistic Nursing Practice, 30(1), pp. 54-57. doi:10.1097/HNP.0000000000000130 Meta-analysis / review
https://doi.org/10.1097/HNP.0000000000000130 - Hudson, J.B (2011) 'Applications of the phytomedicine Echinacea purpurea (Purple Coneflower) in infectious diseases', Journal of Biomedicine & Biotechnology, 2012, pp. 769896. doi:10.1155/2012/769896 Meta-analysis / review
https://doi.org/10.1155/2012/769896 - Mishima, S., Saito, K., Maruyama, H., Inoue, M., Yamashita, T., Ishida, T. and Gu, Y (2004) 'Antioxidant and immuno-enhancing effects of Echinacea purpurea', Biological & Pharmaceutical Bulletin, 27(7), pp. 1004-1009. doi:10.1248/bpb.27.1004 Preclinical
https://doi.org/10.1248/bpb.27.1004 - Saunders, P.R., Smith, F. and Schusky, R.W (2007) 'Echinacea purpurea L. in children: safety, tolerability, compliance, and clinical effectiveness in upper respiratory tract infections', Canadian Journal of Physiology and Pharmacology, 85(11), pp. 1195-1199. doi:10.1139/Y07-103 Clinical study
https://doi.org/10.1139/Y07-103 - Micheli, L., Maggini, V., Ciampi, C., Gallo, E., Bogani, P., Fani, R., Pistelli, L., Ghelardini, C., Di Cesare Mannelli, L., De Leo, M. and Firenzuoli, F (2022) 'Echinacea purpurea against neuropathic pain: Alkamides versus polyphenols efficacy', Phytotherapy Research, 37(5), pp. 1911-1923. doi:10.1002/ptr.7709 Preclinical
https://doi.org/10.1002/ptr.7709 - Gholami, M., Amri, J., Pazhoohan, S. and Sadegh, M (2021) 'Anticonvulsive and anti-epileptogenesis effects of Echinacea purpurea root extract, an involvement of CB2 receptor', Journal of Complementary & Integrative Medicine, 19(4), pp. 879-886. doi:10.1515/jcim-2020-0219 Preclinical
https://doi.org/10.1515/jcim-2020-0219 - Awortwe, C., Bruckmueller, H., Kaehler, M. and Cascorbi, I (2021) 'Interaction of Phytocompounds of Echinacea purpurea with ABCB1 and ABCG2 Efflux Transporters', Molecular Pharmaceutics, 18(4), pp. 1622-1633. doi:10.1021/acs.molpharmaceut.0c01075 Preclinical
https://doi.org/10.1021/acs.molpharmaceut.0c01075 - Perry, N.B., van Klink, J.W., Burgess, E.J. and Parmenter, G.A (1997) 'Alkamide levels in Echinacea purpurea: a rapid analytical method revealing differences among roots, rhizomes, stems, leaves and flowers', Planta Medica, 63(1), pp. 58-62. doi:10.1055/s-2006-957605 Preclinical
https://doi.org/10.1055/s-2006-957605 - Linde, K., Barrett, B., Wölkart, K., Bauer, R. and Melchart, D (2006) 'Echinacea for preventing and treating the common cold'. Traditional / reference
https://scholar.google.com/scholar?q=Echinacea%20for%20preventing%20and%20treating%20the%20common%20cold - Sharma, M., Schoop, R., Suter, A. and Schoop, W (2010) 'The possibility of prophylactic treatment of streptococcal pharyngotonsillitis with a standardized Echinacea preparation', 29(8), pp. 1025--1035. Traditional / reference
https://scholar.google.com/scholar?q=The%20possibility%20of%20prophylactic%20treatment%20of%20streptococcal%20pharyngotonsillitis%20with%20a%20standardized%20Echinacea%20preparation - World Health Organization (1999) 'WHO Monographs on Selected Medicinal Plants'. Traditional / reference
https://scholar.google.com/scholar?q=WHO%20Monographs%20on%20Selected%20Medicinal%20Plants - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Gorski, J.C., Huang, S.M., Pinto, A., Hamman, M.A., Hilligoss, J.K., Zaheer, N.A., Desai, M., Miller, M. and Hall, S.D (2004) 'The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo', Clinical Pharmacology and Therapeutics, 75(1), pp. 89-100. doi:10.1016/j.clpt.2003.09.013 Clinical study
https://doi.org/10.1016/j.clpt.2003.09.013
- Jurado, P., Uruen, C., Martinez, S., Lain, E. and others (2023) 'Essential oils of Pinus sylvestris, Citrus limon and Origanum vulgare exhibit high bactericidal and anti-biofilm activities against Neisseria gonorrhoeae and Streptococcus suis', Biomedicine & Pharmacotherapy, 168, pp. 115703. doi:10.1016/j.biopha.2023.115703 Preclinical
https://doi.org/10.1016/j.biopha.2023.115703 - Csikos, E., Cseko, K., Kemeny, A., Draskoczi, L. and others (2022) 'Pinus sylvestris L. and Syzygium aromaticum (L.) Merr. & L. M. Perry Essential Oils Inhibit Endotoxin-Induced Airway Hyperreactivity despite Aggravated Inflammatory Mechanisms in Mice', Molecules, 27(12), pp. 3868. doi:10.3390/molecules27123868 Preclinical
https://doi.org/10.3390/molecules27123868 - Allenspach, M., Valder, C., Flamm, D., Grisoni, F. and others (2020) 'Verification of Chromatographic Profile of Primary Essential Oil of Pinus sylvestris L. Combined with Chemometric Analysis', Molecules, 25(13), pp. 2973. doi:10.3390/molecules25132973 Preclinical
https://doi.org/10.3390/molecules25132973 - Allenspach, M., Valder, C., Flamm, D. and Steuer, C (2021) 'Authenticity control of Pinus sylvestris essential oil by chiral gas chromatographic analysis of alpha-pinene', Scientific Reports, 11(1), pp. 16923. doi:10.1038/s41598-021-96356-x Preclinical
https://doi.org/10.1038/s41598-021-96356-x - Rodrigues, A.M., Mendes, M.D., Lima, A.S., Barbosa, P.M. and others (2017) 'Pinus halepensis, Pinus pinaster, Pinus pinea and Pinus sylvestris Essential Oils Chemotypes and Monoterpene Hydrocarbon Enantiomers', Chemistry & Biodiversity, 14(1), pp. e1600153. doi:10.1002/cbdv.201600153 Preclinical
https://doi.org/10.1002/cbdv.201600153 - Judzentiene, A., Stikliene, A. and Kupcinskiene, E (2007) 'Changes in the essential oil composition in the needles of Scots pine (Pinus sylvestris L.) under anthropogenic stress', The Scientific World Journal, 7(Suppl 1), pp. 141-150. doi:10.1100/tsw.2007.36 Preclinical
https://doi.org/10.1100/tsw.2007.36 - Hoai, N.T., Duc, H.V., Thao, D.T., Orav, A. and others (2015) 'Selectivity of Pinus sylvestris extract and essential oil to estrogen-insensitive breast cancer cells', Pharmacognosy Magazine, 11(Suppl 2), pp. S290-S295. doi:10.4103/0973-1296.166052 Preclinical
https://doi.org/10.4103/0973-1296.166052 - Fayemiwo, K.A., Adeleke, M.A., Okoro, O.P., Awojide, S.H. and others (2014) 'Larvicidal efficacies and chemical composition of essential oils of Pinus sylvestris and Syzygium aromaticum against mosquitoes', Asian Pacific Journal of Tropical Biomedicine, 4(1), pp. 30-34. doi:10.1016/S2221-1691(14)60204-5 Preclinical
https://doi.org/10.1016/S2221-1691(14)60204-5 - Scalas, D., Mandras, N., Roana, J., Tardugno, R. and others (2018) 'Use of Pinus sylvestris L. (Pinaceae), Origanum vulgare L. (Lamiaceae), and Thymus vulgaris L. (Lamiaceae) essential oils and their main components to enhance itraconazole activity against azole susceptible/not-susceptible Cryptococcus neoformans strains', BMC Complementary and Alternative Medicine, 18(1), pp. 143. doi:10.1186/s12906-018-2219-4 Preclinical
https://doi.org/10.1186/s12906-018-2219-4 - Suntar, I., Tumen, I., Ustun, O., Keles, H. and others (2012) 'Appraisal on the wound healing and anti-inflammatory activities of the essential oils obtained from the cones and needles of Pinus species by in vivo and in vitro experimental models', Journal of Ethnopharmacology, 139(2), pp. 533-540. doi:10.1016/j.jep.2011.11.045 Preclinical
https://doi.org/10.1016/j.jep.2011.11.045 - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Bakkali, F. et al (2008) 'Biological effects of essential oils — a review', 46(2), pp. 446--475. doi:10.1016/j.fct.2007.09.106 Preclinical
https://doi.org/10.1016/j.fct.2007.09.106 - Sousa, A. et al (2010) 'Proanthocyanidins from Pinus pinaster bark', 71(1), pp. 64--72. Traditional / reference
https://scholar.google.com/scholar?q=Proanthocyanidins%20from%20Pinus%20pinaster%20bark - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Missouri Poison Center 'Pine Needles'. Available at: https://missouripoisoncenter.org/is-this-a-poison/pine-needles/ Traditional / reference
https://missouripoisoncenter.org/is-this-a-poison/pine-needles/ - Arens, A.M. and Anaebere, T.C. and Horng, H. and Olson, K (2016) 'Fatal Taxus baccata ingestion with perimortem serum taxine B quantification', Clinical Toxicology (Philadelphia, Pa.), 54(9), pp. 878-880. doi:10.1080/15563650.2016.1209765 Clinical study
https://doi.org/10.1080/15563650.2016.1209765 - Froldi, R. and Croci, P.F. and Dell'Acqua, L. and Fare, F. and Tassoni, G. and Gambaro, V (2010) 'Preliminary gas chromatography with mass spectrometry determination of 3,5-dimethoxyphenol in biological specimens as evidence of taxus poisoning', Journal of Analytical Toxicology, 34(1), pp. 53-6. doi:10.1093/jat/34.1.53 Clinical study
https://doi.org/10.1093/jat/34.1.53
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.