Omnia SanaPlant Comparison
Hawthorn vs Cardamom
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Hawthorn and Cardamom: they share 4 indicated uses (arthritis / joint pain, cardiovascular / heart health, inflammation (general), …); 2 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Hawthorn | Cardamom | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Cardiovascular / heart health | 1/10 | 1/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Principal cardioprotective and antioxidant polyphenols characterised by chemical profiling of leaf, flower and fruit.
Contribute to the vasoactive and antioxidant effects, the basis for extract standardisation.
Seed essential oil dominated by 1,8-cineole and alpha-terpinyl acetate, giving the characteristic aroma and much of the carminative, antimicrobial and antioxidant activity.
Additional antioxidant constituents of the seed.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from anticancer action
inferred from anti-inflammatory action
inferred from sedative action
inferred from anti-inflammatory action
inferred from digestive action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
Generally well tolerated. Hawthorn should not replace prescribed cardiac medications without medical supervision. May potentiate the effects of cardiac glycosides (digoxin), antihypertensive drugs, and coronary dilators. Not recommended during pregnancy and breastfeeding due to insufficient safety data. Mild side effects (nausea, dizziness, GI upset) occasionally reported.
Duke (2002) rates hawthorn as +++ — one of the most clinically supported cardiovascular herbs. Clinical evidence (score 2) supports its use for decreasing cardiac output (NYHA functional Stage II heart failure), as recognized by Commission E. Key activities include vasodilation, positive inotropic effects, and antioxidant protection of vascular tissue. Dose: 160–900 mg standardized leaf/flower extract (containing 18.75% oligomeric proanthocyanidins) daily. Duke emphasizes that hawthorn should not replace conventional heart failure therapy, and therapeutic effects may take 4–8 weeks to emerge. Mild interactions with cardiac glycosides (digitalis) are possible (Duke, 2002).
Cardamom is generally considered safe for most people when used in culinary amounts. At medicinal doses (supplement form), rare side effects include mild gastrointestinal discomfort and allergic reactions. There are no well-documented serious drug interactions at culinary doses. Cardamom may mildly lower blood pressure — caution if combined with antihypertensive medications. Some sources suggest potential gallstone formation with very high doses, as cardamom may stimulate bile flow. Avoid therapeutic doses during pregnancy until more safety data are available; culinary use is considered safe. Allergy to other Zingiberaceae (ginger, turmeric) may indicate cross-reactivity risk (Korikanthimath and Hiremath, 2002).
Duke (2002) provides clinical support (score 2) for cardamom as a cholagogue, antiviral agent, and appetite stimulant. Commission E and the German PDR (PHR) approve it for loss of appetite and bronchitis (score 2). The essential oil shows antispasmodic and carminative activity. Dose: 1.5 g ground fruit or equivalent preparation three times daily. Duke rates cardamom as generally safe (++), with no significant contraindications at therapeutic doses (Duke, 2002).
External Ids
Botanical Description
Small deciduous tree or large shrub, densely thorny, with deeply lobed, glossy leaves (more deeply cut than midland hawthorn). Clusters of small, five-petalled white flowers with a strong, musky scent appear in spring ('May blossom'), followed by small red berries (haws), each containing a single seed (nutlet) - the origin of the species name monogyna.[4]
Large, rhizomatous perennial herb with tall, reed-like leafy stems (pseudostems) formed by overlapping leaf sheaths, arising from a stout underground rhizome. Small, pale flowers with a violet-veined white lip are borne on separate trailing panicles that grow along the ground from the base of the plant. The fruit is a small, ridged, pale green three-sided capsule (the cardamom pod) containing numerous dark, aromatic seeds.[1]
Habitat
One of the commonest hedgerow and scrub trees of Europe, growing in hedgerows, woodland edges, scrub and pasture on a wide range of soils; native to Europe, North Africa and Western Asia.[4]
Native to the moist evergreen forests of the Western Ghats of southern India and Sri Lanka; cultivated in warm, humid, shaded tropical conditions, notably in India, Guatemala and Sri Lanka.[1]
Harvesting
Flowers are picked as they open in May, leaves are picked with the young flowering shoots, and the ripe red berries (haws) are gathered in autumn after the first frosts soften them slightly; all three parts are traditionally combined.[4]
The unripe green pods are hand-picked just before full maturity, then carefully dried (traditionally in the shade or by gentle heat) to preserve the green colour and aromatic oil; the pods are typically used whole or the seeds removed and ground just before use.
Traditional Uses
Common hawthorn shares the same long cardiovascular and calming tradition as midland hawthorn, used across European herbal medicine as a heart tonic for mild circulatory complaints, palpitations and nervous tension, and remains one of the most clinically studied cardiovascular botanicals.[4]
Cardamom has a long Ayurvedic, Middle Eastern and Asian tradition as a warming digestive carminative for indigestion and bloating, a remedy for respiratory complaints such as asthma and bronchitis, and a valued spice for tea, coffee and cooking.[1]
Preparations
Leaf-and-flower extract standardised to flavonoid or procyanidin content, taken as tablets or capsules; the best-studied clinical form.
Crushed pods or seeds infused in hot water, or added to tea/coffee, as a traditional carminative digestive preparation.
Dosage
The EU herbal monograph on Crataegus spp., folium cum flore gives dry extracts in divided daily doses of 240-900 mg (single dose 80-450 mg) or, for one quantified extract, 570-1750 mg daily (single dose 190-350 mg), in adults and elderly. If symptoms persist longer than 2 weeks a doctor should be consulted, and hawthorn is never used as a substitute for prescribed heart medication without medical supervision. Educational reference only, not a prescription.
The EU herbal monograph gives 1-2 g of the comminuted leaf and flower in 150 mL of boiling water as an infusion, up to 4 times daily (maximum 6 g daily), in adults and elderly. Educational reference only, not a prescription.
The WHO monograph on Semen Cardamomi gives an average DAILY dosage of 1.5 g of the drug, or equivalent preparations; for tincture, a daily dosage equivalent to 12 g. Note the 1.5 g is a daily total, not a per-dose amount. Educational reference only, not a prescription.
References
Drug Class Interactions
Not documented
Lookalikes Review
References & Sources
- Ez-Zahra Amrati, F., Mssillou, I., Boukhira, S., Djiddi Bichara, M. et al (2024) 'Phenolic Composition of Crataegus monogyna Jacq. Extract and Its Anti-Inflammatory, Hepatoprotective, and Antileukemia Effects', Pharmaceuticals (Basel), 17(6), pp. 786. doi:10.3390/ph17060786 Preclinical
https://doi.org/10.3390/ph17060786 - Lis, M., Szczypka, M., Suszko-Pawłowska, A., Sokół-Łętowska, A. et al (2019) 'Hawthorn (Crataegus monogyna) Phenolic Extract Modulates Lymphocyte Subsets and Humoral Immune Response in Mice', Planta Medica, 86(2), pp. 160-168. doi:10.1055/a-1045-5437 Preclinical
https://doi.org/10.1055/a-1045-5437 - Paun, G., Neagu, E., Albu, C., Alecu, A. et al (2024) 'Antioxidant and Antidiabetic Activity of Crataegus monogyna L. and Cornus mas Fruit Extracts', Molecules, 29(15), pp. 3595. doi:10.3390/molecules29153595 Preclinical
https://doi.org/10.3390/molecules29153595 - Nabavi, S.F., Habtemariam, S., Ahmed, T., Sureda, A., Daglia, M. and Sobarzo-Sanchez, E (2015) 'Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications', Nutrients, 7(9), pp. 7708-7728. doi:10.3390/nu7095361 Meta-analysis / review
https://doi.org/10.3390/nu7095361 - Belabdelli, F., Bekhti, N., Piras, A., Benhafsa, F.M., Ilham, M. and Adil, S (2021) 'Chemical composition, antioxidant and antibacterial activity of Crataegus monogyna leaves' extracts', Natural Product Research, 36(12), pp. 3234-3239. doi:10.1080/14786419.2021.1958215 Preclinical
https://doi.org/10.1080/14786419.2021.1958215 - Jalali, A.S., Hasanzadeh, S. and Malekinejad, H (2012) 'Crataegus monogyna aqueous extract ameliorates cyclophosphamide-induced toxicity in rat testis: stereological evidences', Acta Medica Iranica, 50(1), pp. 1-8. Preclinical
https://scholar.google.com/scholar?q=Crataegus%20monogyna%20aqueous%20extract%20ameliorates%20cyclophosphamide-induced%20toxicity%20in%20rat%20testis%3A%20stereological%20evidences - Martin-Garcia, B., Razola-Diaz, M.D.C., Gomez-Caravaca, A.M., Benitez, G. and Verardo, V (2021) 'Setup of an Ultrasonic-Assisted Extraction to Obtain High Phenolic Recovery in Crataegus monogyna Leaves', Molecules, 26(15), pp. 4536. doi:10.3390/molecules26154536 Preclinical
https://doi.org/10.3390/molecules26154536 - Arslan, R., Bektas, N., Bor, Z. and Sener, E (2014) 'Evaluation of the antithrombotic effects of Crataegus monogyna and Crataegus davisii in the carrageenan-induced tail thrombosis model', Pharmaceutical Biology, 53(2), pp. 275-279. doi:10.3109/13880209.2014.914957 Preclinical
https://doi.org/10.3109/13880209.2014.914957 - Edwards, J.E., Brown, P.N., Talent, N., Dickinson, T.A. and Shipley, P.R (2012) 'A review of the chemistry of the genus Crataegus', Phytochemistry, 79, pp. 5-26. doi:10.1016/j.phytochem.2012.04.006 Meta-analysis / review
https://doi.org/10.1016/j.phytochem.2012.04.006 - Jarzycka, A., Lewinska, A., Gancarz, R. and Wilk, K.A (2013) 'Assessment of extracts of Helichrysum arenarium, Crataegus monogyna, Sambucus nigra in photoprotective UVA and UVB; photostability in cosmetic emulsions', Journal of Photochemistry and Photobiology B: Biology, 128, pp. 50-57. doi:10.1016/j.jphotobiol.2013.07.029 Preclinical
https://doi.org/10.1016/j.jphotobiol.2013.07.029 - Lucconi, G., Chlapanidas, T., Martino, E., Gaggeri, R., Perteghella, S. and Rossi, D (2013) 'Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity', Pharmaceutical Development and Technology, 19(1), pp. 65-72. doi:10.3109/10837450.2012.752387 Preclinical
https://doi.org/10.3109/10837450.2012.752387 - Zorniak, M., Szydlo, B. and Krzeminski, T.F (2017) 'Crataegus special extract WS 1442: up-to-date review of experimental and clinical experiences', Journal of Physiology and Pharmacology, 68(4), pp. 521-526. Meta-analysis / review
https://scholar.google.com/scholar?q=Crataegus%20special%20extract%20WS%201442%3A%20up-to-date%20review%20of%20experimental%20and%20clinical%20experiences - European Medicines Agency (2016) 'European Union herbal monograph on Crataegus spp., folium cum flore'. Traditional / reference
https://scholar.google.com/scholar?q=European%20Union%20herbal%20monograph%20on%20Crataegus%20spp.%2C%20folium%20cum%20flore - Pittler, M.H., Guo, R. and Ernst, E (2008) 'Hawthorn extract for treating chronic heart failure'. Traditional / reference
https://scholar.google.com/scholar?q=Hawthorn%20extract%20for%20treating%20chronic%20heart%20failure - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Tankanow, R., Tamer, H.R., Streetman, D.S., Smith, S.G., Welton, J.L., Annesley, T., Aaronson, K.D. and Bleske, B.E (2003) 'Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha)', Journal of Clinical Pharmacology, 43(6), pp. 637-642. doi:10.1177/0091270003253417 Randomized trial
https://doi.org/10.1177/0091270003253417 - Pittler, M.H., Guo, R. and Ernst, E (2008) 'Hawthorn extract for treating chronic heart failure', Cochrane Database of Systematic Reviews, 2008(1), pp. CD005312. doi:10.1002/14651858.CD005312.pub2 Meta-analysis / review
https://doi.org/10.1002/14651858.CD005312.pub2 - Pittler, M.H., Guo, R. and Ernst, E (2008) 'Hawthorn extract for treating chronic heart failure', Cochrane Database of Systematic Reviews, 2008(1), pp. CD005312. doi:10.1002/14651858.CD005312.pub2 Meta-analysis / review
https://doi.org/10.1002/14651858.CD005312.pub2 - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003
- Ashokkumar, K., Murugan, M., Dhanya, M.K. and Warkentin, T.D (2019) 'Botany, traditional uses, phytochemistry and biological activities of cardamom [Elettaria cardamomum (L.) Maton] - A critical review', Journal of Ethnopharmacology, 246, pp. 112244. doi:10.1016/j.jep.2019.112244 Meta-analysis / review
https://doi.org/10.1016/j.jep.2019.112244 - Jamal, A., Javed, K., Aslam, M. and Jafri, M.A (2006) 'Gastroprotective effect of cardamom, Elettaria cardamomum Maton. fruits in rats', Journal of Ethnopharmacology, 103(2), pp. 149-153. doi:10.1016/j.jep.2005.07.016 Preclinical
https://doi.org/10.1016/j.jep.2005.07.016 - Yahyazadeh, R., Ghasemzadeh Rahbardar, M., Razavi, B.M., Karimi, G. and Hosseinzadeh, H (2021) 'The effect of Elettaria cardamomum (cardamom) on the metabolic syndrome: Narrative review', Iranian Journal of Basic Medical Sciences, 24(11), pp. 1462-1469. doi:10.22038/IJBMS.2021.54417.12228 Meta-analysis / review
https://doi.org/10.22038/IJBMS.2021.54417.12228 - Cardenas Garza, G.R., Elizondo Luevano, J.H., Bazaldua Rodriguez, A.F., Chavez Montes, A., Perez Hernandez, R.A. and Martinez Delgado, A.J (2021) 'Benefits of Cardamom (Elettaria cardamomum (L.) Maton) and Turmeric (Curcuma longa L.) Extracts for Their Applications as Natural Anti-Inflammatory Adjuvants', Plants, 10(9), pp. 1908. doi:10.3390/plants10091908 Preclinical
https://doi.org/10.3390/plants10091908 - Sreedharan, S., Nair, V. and Cisneros-Zevallos, L (2023) 'Protective Role of Phenolic Compounds from Whole Cardamom (Elettaria cardamomum (L.) Maton) against LPS-Induced Inflammation in Colon and Macrophage Cells', Nutrients, 15(13), pp. 2965. doi:10.3390/nu15132965 Preclinical
https://doi.org/10.3390/nu15132965 - Almeer, R.S., Alnasser, M., Aljarba, N. and AlBasher, G.I (2021) 'Effects of Green cardamom (Elettaria cardamomum Maton) and its combination with cyclophosphamide on Ehrlich solid tumors', BMC Complementary Medicine and Therapies, 21(1), pp. 133. doi:10.1186/s12906-021-03305-2 Preclinical
https://doi.org/10.1186/s12906-021-03305-2 - Almohammed, H.I., Alkhaibari, A.M. and Alanazi, A.D (2022) 'Antiparasitic effects of Elettaria cardamomum L. essential oil and its main compounds, 1,8-Cineole alone and in combination with albendazole against Echinococcus granulosus protoscoleces', Saudi Journal of Biological Sciences, 29(4), pp. 2811-2818. doi:10.1016/j.sjbs.2022.01.005 Preclinical
https://doi.org/10.1016/j.sjbs.2022.01.005 - Pavarino, M., Marengo, A., Cagliero, C., Bicchi, C., Rubiolo, P. and Sgorbini, B (2023) 'Elettaria cardamomum (L.) Maton Essential Oil: An Interesting Source of Bioactive Specialized Metabolites as Inhibitors of Acetylcholinesterase and Butyrylcholinesterase', Plants, 12(19), pp. 3463. doi:10.3390/plants12193463 Preclinical
https://doi.org/10.3390/plants12193463 - Masoumi-Ardakani, Y., Mahmoudvand, H., Mirzaei, A., Esmaeilpour, K., Ghazvini, H. and Khalifeh, S (2017) 'The effect of Elettaria cardamomum extract on anxiety-like behavior in a rat model of post-traumatic stress disorder', Biomedicine & Pharmacotherapy, 87, pp. 489-495. doi:10.1016/j.biopha.2016.12.116 Preclinical
https://doi.org/10.1016/j.biopha.2016.12.116 - Delgadillo-Puga, C., Torre-Villalvazo, I., Carino-Cervantes, Y.Y., Garcia-Luna, C., Soberanes-Chavez, P. and de Gortari, P (2023) 'Cardamom (Elettaria cardamomum (L.) Maton) Seeds Intake Increases Energy Expenditure and Reduces Fat Mass in Mice by Modulating Neural Circuits That Regulate Adipose Tissue Lipolysis and Mitochondrial Oxidative Metabolism in Liver and Skeletal Muscle', International Journal of Molecular Sciences, 24(4), pp. 3909. doi:10.3390/ijms24043909 Preclinical
https://doi.org/10.3390/ijms24043909 - World Health Organization (2009) 'Semen Cardamomi'. Available at: https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 Traditional / reference
https://iris.who.int/items/6418d8af-5200-4e6b-9bf5-004f3aa62a37 - Bhilave, M.P., Bhosale, S.V. and Nadaf, S.B (2013) 'Evaluation of antibacterial activity of cardamom seeds of Elettaria cardamomum', 4(1), pp. 66--69. Traditional / reference
https://scholar.google.com/scholar?q=Evaluation%20of%20antibacterial%20activity%20of%20cardamom%20seeds%20of%20Elettaria%20cardamomum - Jamal, A., Javed, K., Aslam, M. and Jafri, M.A (2006) 'Gastroprotective effect of cardamom, Elettaria cardamomum (Maton) Fruits in Rats', 103(2), pp. 149--153. doi:10.1016/j.jep.2005.09.040 Traditional / reference
https://doi.org/10.1016/j.jep.2005.09.040 - Korikanthimath, V.S. and Hiremath, G.M (2002) 'Cardamom (Elettaria cardamomum Maton)', pp. 144--157. Traditional / reference
https://scholar.google.com/scholar?q=Cardamom%20%28Elettaria%20cardamomum%20Maton%29 - Royal Botanic Gardens, Kew (n.d.) 'Elettaria cardamomum (L.) Maton'. Available at: https://powo.science.kew.org/taxon/urn:lsid:http://ipni.org:names:796793-1 Traditional / reference
https://powo.science.kew.org/taxon/urn:lsid:http://ipni.org:names:796793-1 - Verma, S.K., Jain, V. and Katewa, S.S (2009) 'Blood pressure lowering, fibrinolysis enhancing and antioxidant activities of cardamom (Elettaria cardamomum)', 46(6), pp. 503--506. Traditional / reference
https://scholar.google.com/scholar?q=Blood%20pressure%20lowering%2C%20fibrinolysis%20enhancing%20and%20antioxidant%20activities%20of%20cardamom%20%28Elettaria%20cardamomum%29 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.