Plant Comparison
Coriander vs Elecampane
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Coriander and Elecampane: they share 5 indicated uses (arthritis / joint pain, infection (general), inflammation (general), …); 2 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Coriander | Elecampane | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 2/10 | Comparable evidence |
| Infection (general) | 1/10 | 2/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 2/10 | Comparable evidence |
| Skin irritation | 1/10 | 2/10 | Comparable evidence |
| Wounds | 1/10 | 2/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Seed essential oil dominated by linalool, giving the characteristic aroma and much of the antimicrobial and carminative activity.
Antioxidant flavonoids and phenolics, notably quercetin derivatives, identified across leaf and seed extracts.
The antimicrobial and anti-inflammatory principles of the root; the eudesmane core and the alpha,beta-methylene-lactone ring are essential for the antimicrobial activity.
A fructan polysaccharide abundant in the root (the genus Inula gives inulin its name).
Pharmacological Actions
Anti-inflammatory - sesquiterpene lactones (alantolactone, isoalantolactone) inhibit NF-kB and MAPK signalling and pro-inflammatory cytokines; total sesquiterpene lactones eased arthritis in animal models (potential in rheumatoid arthritis)
Antimicrobial, notably anti-staphylococcal (membrane-damaging) and anti-mycobacterial (active against Mycobacterium tuberculosis in vitro); supports respiratory and skin infection
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from antispasmodic action
inferred from antispasmodic action
inferred from anti-inflammatory action
Anti-inflammatory - sesquiterpene lactones (alantolactone, isoalantolactone) inhibit NF-kB and MAPK signalling and pro-inflammatory cytokines; total sesquiterpene lactones eased arthritis in animal models (potential in rheumatoid arthritis)
Expectorant for productive cough and bronchitis (long-standing respiratory remedy)
inferred from anticancer action
Expectorant for productive cough and bronchitis (long-standing respiratory remedy); Soothes irritated airways / chronic catarrh (traditional)
Antimicrobial, notably anti-staphylococcal (membrane-damaging) and anti-mycobacterial (active against Mycobacterium tuberculosis in vitro); supports respiratory and skin infection
inferred from anti-inflammatory action
inferred from expectorant action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
• Food use is generally safe for most people (leaf in salads, seed as spice) (Burdock & Carabin, 2009). • Allergy is the main “big warning.” Coriander can trigger reactions ranging from mild oral itching to more serious allergy in sensitive people, especially those with pollen allergies (e.g., birch/mugwort) or other Apiaceae spice allergies (Thermo Fisher/Phadia, n.d.; Berghea et al., 2025). • If you use supplements (capsules/powder) and you take diabetes medication, be cautious: coriander seed powder has shown blood-sugar improvements in a small human trial, so it may add to the effect of glucose-lowering meds (Zamany et al., 2025). • Essential oil is not the same as the spice. Coriander essential oil is highly concentrated and should not be taken internally in “DIY doses.” It can be irritating, and safety data are discussed mainly for food-flavouring levels—not self-prescribed medicinal dosing (Burdock & Carabin, 2009). • Pregnancy / breastfeeding: normal culinary amounts are generally considered fine; “medicinal-dose” supplements or essential oil are best avoided unless guided by a qualified professional because safety data at higher doses is limited (Burdock & Carabin, 2009).
Duke (2002) provides clinical evidence (score 2) for coriander's role as an aperitif (appetite stimulant) and digestive tonic, consistent with Commission E approval. It demonstrates antispasmodic, carminative, and antifungal activities at the experimental level. Dose: 1–3 g crushed fruits (seeds) three times daily, or equivalent preparations. Duke notes mild hypoglycemic activity and a potential antiimplantation effect in high doses — use with caution in women attempting pregnancy (Duke, 2002).
The sesquiterpene lactones (especially alantolactone) are known skin sensitisers and can cause allergic contact dermatitis; people sensitive to the daisy family (Asteraceae) should be cautious.
Large doses can cause nausea, vomiting and diarrhoea; safety in pregnancy and breastfeeding is not established, so avoid medicinal doses.
External Ids
Botanical Description
Slender annual herb with delicate, broad, lobed lower leaves and finely divided, feathery upper leaves - a marked contrast within the same plant. Small white or pale pink flowers are borne in flat compound umbels, followed by round, ridged, aromatic seeds. The fresh leaf ('cilantro') has a distinctive citrusy aroma, often described as soapy by those with a genetic sensitivity to it.[4]
Tall, robust perennial herb with large, coarse, hairy leaves - broadly oval near the base and progressively smaller up the stem - arising from a thick, aromatic rhizome. Large, shaggy, bright yellow daisy-like flower heads with numerous narrow ray florets are borne at the top of stout, branching stems.[12]
Habitat
Believed native to the Mediterranean region and Western Asia; cultivated worldwide as a culinary herb and spice crop on well-drained, sunny sites.[4]
Grows in damp meadows, pastures, roadsides and woodland margins on moist, rich soils; native to Europe and Western Asia and naturalised in North America.[12]
Harvesting
Leaves are picked fresh through the growing season, before the plant bolts (flowers), when the flavour is best; the seed is harvested in late summer once the umbels have browned and dried, then threshed; the root can be dug at the same time as young leaves.
The root and rhizome are dug in autumn of the second or later year, when sesquiterpene lactone and inulin content is highest, then cleaned, sliced and dried.[12]
Traditional Uses
Coriander seed and leaf have a very long culinary and medicinal history across the Mediterranean, Middle East and Asia as a digestive carminative for indigestion, bloating and cramping, and, more recently, studied for calming/anxiolytic effects on the central nervous system alongside cardiovascular and metabolic benefits.[1, 4]
Elecampane root has a long European tradition, reflected in the old name 'elf dock', as a warming expectorant remedy for productive cough, bronchitis and chronic respiratory catarrh, and topically and internally as an antimicrobial for skin and wound infections.[12]
Preparations
References
Lookalikes Review
Dangerous Lookalikes
Not documented
References & Sources
- Santibáñez, A., Jiménez-Ferrer, E., Angulo-Bejarano, P.I., Sharma, A. and Herrera-Ruiz, M (2023) 'Coriandrum sativum and Its Utility in Psychiatric Disorders', Molecules, 28(14), pp. 5314. doi:10.3390/molecules28145314 Traditional / reference
https://doi.org/10.3390/molecules28145314 - Wei, J.N., Liu, Z.H., Zhao, Y.P., Zhao, L.L. et al (2019) 'Phytochemical and bioactive profile of Coriandrum sativum L', Food Chemistry, 286, pp. 260-267. doi:10.1016/j.foodchem.2019.01.171 Traditional / reference
https://doi.org/10.1016/j.foodchem.2019.01.171 - Hosseini, M., Boskabady, M.H. and Khazdair, M.R (2021) 'Neuroprotective effects of Coriandrum sativum and its constituent, linalool: A review', Avicenna Journal of Phytomedicine, 11(5), pp. 436-450. doi:10.22038/AJP.2021.55681.2786 Traditional / reference
https://doi.org/10.22038/AJP.2021.55681.2786 - Mahleyuddin, N.N., Moshawih, S., Ming, L.C., Zulkifly, H.H., Kifli, N. and Loy, M.J (2021) 'Coriandrum sativum L.: A Review on Ethnopharmacology, Phytochemistry, and Cardiovascular Benefits', Molecules, 27(1), pp. 209. doi:10.3390/molecules27010209 Meta-analysis / review
https://doi.org/10.3390/molecules27010209 - Prachayasittikul, V., Prachayasittikul, S., Ruchirawat, S. and Prachayasittikul, V (2017) 'Coriander (Coriandrum sativum): A promising functional food toward the well-being', Food Research International, 105, pp. 305-323. doi:10.1016/j.foodres.2017.11.019 Meta-analysis / review
https://doi.org/10.1016/j.foodres.2017.11.019 - Laribi, B., Kouki, K., M'Hamdi, M. and Bettaieb, T (2015) 'Coriander (Coriandrum sativum L.) and its bioactive constituents', Fitoterapia, 103, pp. 9-26. doi:10.1016/j.fitote.2015.03.012 Meta-analysis / review
https://doi.org/10.1016/j.fitote.2015.03.012 - Sahib, N.G., Anwar, F., Gilani, A.H., Hamid, A.A., Saari, N. and Alkharfy, K.M (2012) 'Coriander (Coriandrum sativum L.): a potential source of high-value components for functional foods and nutraceuticals - a review', Phytotherapy Research, 27(10), pp. 1439-1456. doi:10.1002/ptr.4897 Meta-analysis / review
https://doi.org/10.1002/ptr.4897 - Scandar, S., Zadra, C. and Marcotullio, M.C (2023) 'Coriander (Coriandrum sativum) Polyphenols and Their Nutraceutical Value against Obesity and Metabolic Syndrome', Molecules, 28(10), pp. 4187. doi:10.3390/molecules28104187 Meta-analysis / review
https://doi.org/10.3390/molecules28104187 - Al-Khayri, J.M., Banadka, A., Nandhini, M., Nagella, P., Al-Mssallem, M.Q. and Alessa, F.M (2023) 'Coriandrum sativum Essential Oil: A review on Its Phytochemistry and Biological Activity', Molecules, 28(2), pp. 696. doi:10.3390/molecules28020696 Meta-analysis / review
https://doi.org/10.3390/molecules28020696 - Kukner, A., Soyler, G., Toros, P., Dede, G., Mericli, F. and Isik, S (2020) 'Protective effect of Coriandrum sativum extract against inflammation and apoptosis in liver ischaemia/reperfusion injury', Folia Morphologica, 80(2), pp. 363-371. doi:10.5603/FM.a2020.0060 Preclinical
https://doi.org/10.5603/FM.a2020.0060 - Liu, Q.F., Jeong, H., Lee, J.H., Hong, Y.K., Oh, Y. and Kim, Y.M (2016) 'Coriandrum sativum Suppresses Abeta42-Induced ROS Increases, Glial Cell Proliferation, and ERK Activation', American Journal of Chinese Medicine, 44(7), pp. 1325-1347. doi:10.1142/S0192415X16500749 Preclinical
https://doi.org/10.1142/S0192415X16500749 - Koppula, S., Alluri, R. and Kopalli, S.R (2021) 'Coriandrum sativum attenuates microglia mediated neuroinflammation and MPTP-induced behavioral and oxidative changes in Parkinson's disease mouse model', EXCLI Journal, 20, pp. 835-850. doi:10.17179/excli2021-3668 Preclinical
https://doi.org/10.17179/excli2021-3668 - Laribi, B., Kouki, K., M'Hamdi, M. and Bettaieb, T (2015) 'Coriander (Coriandrum sativum L.) and its bioactive constituents', pp. 9--26. Traditional / reference
https://scholar.google.com/scholar?q=Coriander%20%28Coriandrum%20sativum%20L.%29%20and%20its%20bioactive%20constituents - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - World Health Organization (1999) 'WHO Monographs on Selected Medicinal Plants'. Traditional / reference
https://scholar.google.com/scholar?q=WHO%20Monographs%20on%20Selected%20Medicinal%20Plants - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Dayan, A.D (2024) 'Death of Socrates: a likely case of poison hemlock (Conium maculatum) poisoning', Clinical Toxicology (Philadelphia, Pa.), 62(1), pp. 56-60. doi:10.1080/15563650.2024.2309328 Clinical study
https://doi.org/10.1080/15563650.2024.2309328 - King County Noxious Weeds (2024) 'Poison hemlock (Conium maculatum) identification and control'. Available at: https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock Traditional / reference
https://kingcounty.gov/en/dept/dnrp/nature-recreation/environment-ecology-conservation/noxious-weeds/identification-control/poison-hemlock - Grow Forage Cook Ferment 'Poison Hemlock: How to Identify and Potential Look-alikes'. Available at: https://www.growforagecookferment.com/poison-hemlock/ Traditional / reference
https://www.growforagecookferment.com/poison-hemlock/ - Teuscher, E. and Greger, H. and Adrian, V (1990) 'Toxicity of Aethusa cynapium L. (fool's parsley)', Pharmazie, 45(7), pp. 537-8. Available at: https://pubmed.ncbi.nlm.nih.gov/2236201/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/2236201/ - Minnesota Wildflowers (2024) 'Aethusa cynapium (Fool's Parsley)'. Available at: https://www.minnesotawildflowers.info/flower/fools-parsley Traditional / reference
https://www.minnesotawildflowers.info/flower/fools-parsley - Botanical Society of Scotland (2023) 'Plant of the Week: Fool's Parsley (Aethusa cynapium)'. Available at: https://botsoc.scot/2023/08/20/plant-of-the-week-21st-august-2023-fools-parsley-aethusa-cynapium/ Traditional / reference
https://botsoc.scot/2023/08/20/plant-of-the-week-21st-august-2023-fools-parsley-aethusa-cynapium/
- Gierlikowska, B., Gierlikowski, W., Bekier, K., Skalicka-Wozniak, K., Czerwinska, M.E. and Kiss, A.K (2019) 'Inula helenium and Grindelia squarrosa as a source of compounds with anti-inflammatory activity in human neutrophils and cultured human respiratory epithelium', Journal of Ethnopharmacology, 249, pp. 112311. doi:10.1016/j.jep.2019.112311 Preclinical
https://doi.org/10.1016/j.jep.2019.112311 - Gao, S. and Wang, Q. and Tian, X.H. and Li, H.L. and Shen, Y.H. and Xu, X.K. and Wu, G.Z. and Hu, Z.L. and Zhang, W.D (2016) 'Total sesquiterpene lactones prepared from Inula helenium L. has potentials in prevention and therapy of rheumatoid arthritis', Journal of Ethnopharmacology, pp. 39--46. doi:10.1016/j.jep.2016.12.020 Preclinical
https://doi.org/10.1016/j.jep.2016.12.020 - Wang, Q., Gao, S., Wu, G., Yang, N., Zu, X., Li, W., Xie, N., Zhang, R., Li, C., Hu, Z. and Zhang, W (2018) 'Total sesquiterpene lactones isolated from Inula helenium L. attenuates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice', Phytomedicine, 46, pp. 78-84. doi:10.1016/j.phymed.2018.04.036 Preclinical
https://doi.org/10.1016/j.phymed.2018.04.036 - Dao, T.T.P., Song, K., Kim, J.Y. and Kim, Y.S (2020) 'Igalan from Inula helenium (L.) suppresses the atopic dermatitis-like response in stimulated HaCaT keratinocytes via JAK/STAT3 signaling', Inflammation Research, 69(3), pp. 309-319. doi:10.1007/s00011-020-01322-4 Preclinical
https://doi.org/10.1007/s00011-020-01322-4 - He, X., Zhao, W., Shao, B., Zhang, B., Liu, T., Sun, C., Huang, H., Wu, J., Liang, J. and Ma, X (2020) 'Natural soluble epoxide hydrolase inhibitors from Inula helenium and their interactions with soluble epoxide hydrolase', International Journal of Biological Macromolecules, 161, pp. 1465-1474. doi:10.1016/j.ijbiomac.2020.04.227 Preclinical
https://doi.org/10.1016/j.ijbiomac.2020.04.227 - Buza, V., Niculae, M., Hanganu, D., Pall, E., Burtescu, R.F., Olah, N., Matei-Latiu, M., Vlasiuc, I., Iozon, I., Szakacs, A.R., Ielciu, I. and Stefanut, L.C (2022) 'Biological Activities and Chemical Profile of Gentiana asclepiadea and Inula helenium Ethanolic Extracts', Molecules, 27(11), pp. 3560. doi:10.3390/molecules27113560 Preclinical
https://doi.org/10.3390/molecules27113560 - Zheng, X., Wu, Z., Xu, J., Zhang, X., Tu, Y., Lei, J., Yuan, R., Cheng, H., Wang, Q. and Yu, J (2021) 'Bioactive sesquiterpenes from Inula helenium', Bioorganic Chemistry, 114, pp. 105066. doi:10.1016/j.bioorg.2021.105066 Preclinical
https://doi.org/10.1016/j.bioorg.2021.105066 - Nder, A.E (2021) 'Efficacy of methanol-water extract of Inula helenium root against oxidative DNA damage', Journal of Traditional Chinese Medicine, 41(2), pp. 293-300. Preclinical
https://scholar.google.com/scholar?q=Efficacy%20of%20methanol-water%20extract%20of%20Inula%20helenium%20root%20against%20oxidative%20DNA%20damage - Chun, J., Song, K. and Kim, Y.S (2018) 'Sesquiterpene lactones-enriched fraction of Inula helenium L. induces apoptosis through inhibition of signal transducers and activators of transcription 3 signaling pathway in MDA-MB-231 breast cancer cells', Phytotherapy Research, 32(12), pp. 2501-2509. doi:10.1002/ptr.6189 Preclinical
https://doi.org/10.1002/ptr.6189 - Li, Y., Ni, Z., Zhu, M., Dong, M., Wang, S., Shi, Q., Zhang, M., Wang, Y., Huo, C., Kiyota, H. and Cong, B (2012) 'Antitumour activities of sesquiterpene lactones from Inula helenium and Inula japonica', Zeitschrift fur Naturforschung C, 67(7-8), pp. 375-380. doi:10.1515/znc-2012-7-804 Preclinical
https://doi.org/10.1515/znc-2012-7-804 - Yan, Y.Y., Zhang, Q., Zhang, B., Yang, B. and Lin, N.M (2019) 'Active ingredients of Inula helenium L. exhibits similar anti-cancer effects as isoalantolactone in pancreatic cancer cells', Natural Product Research, 34(17), pp. 2539-2544. doi:10.1080/14786419.2018.1543676 Preclinical
https://doi.org/10.1080/14786419.2018.1543676 - Kenny, C.R., Stojakowska, A., Furey, A. and Lucey, B (2022) 'From Monographs to Chromatograms: The Antimicrobial Potential of Inula helenium L. (Elecampane) Naturalised in Ireland', Molecules. doi:10.3390/molecules27041406 Traditional / reference
https://doi.org/10.3390/molecules27041406 - Stojanovic-Radic, Z. and Comic, Lj. and Radulovic, N. and Blagojevic, P. and Denic, M. and Miltojevic, A. and Rajkovic, J. and Mihajilov-Krstev, T (2012) 'Antistaphylococcal activity of Inula helenium L. root essential oil: eudesmane sesquiterpene lactones induce cell membrane damage', European Journal of Clinical Microbiology & Infectious Diseases, 31(6), pp. 1015--1025. doi:10.1007/s10096-011-1400-1 Preclinical
https://doi.org/10.1007/s10096-011-1400-1 - Cantrell, C.L. and Abate, L. and Fronczek, F.R. and Franzblau, S.G. and Quijano, L. and Fischer, N.H (1999) 'Antimycobacterial eudesmanolides from Inula helenium and Rudbeckia subtomentosa', Planta Medica, 65(4), pp. 351--355. doi:10.1055/s-1999-14001 Preclinical
https://doi.org/10.1055/s-1999-14001
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.