Plant Comparison
True Cinnamon vs Hawthorn
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
True Cinnamon and Hawthorn: they share 5 indicated uses (arthritis / joint pain, cancer (anticancer research), cardiovascular / heart health, …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | True Cinnamon | Hawthorn | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 7/10 | 1/10 | Stronger for True Cinnamon |
| Cancer (anticancer research) | 2/10 | 2/10 | Comparable evidence |
| Cardiovascular / heart health | 10/10 | 1/10 | Stronger for True Cinnamon |
| Inflammation (general) | 7/10 | 1/10 | Stronger for True Cinnamon |
| Skin irritation | 7/10 | 1/10 | Stronger for True Cinnamon |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Trans-cinnamaldehyde is the principal constituent of cinnamon bark essential oil and the main driver of its antimicrobial, antifungal (anti-Candida) and anti-inflammatory activity, acting partly by damaging microbial cell membranes and inhibiting NF-kB signalling.
Cassia cinnamon (C. cassia) contains high levels of coumarin, which is potentially hepatotoxic in excess; true Ceylon cinnamon (C. verum) contains only trace coumarin and is the safer culinary/medicinal choice. Several pooled clinical and antimicrobial studies do not distinguish the two species.
Principal cardioprotective and antioxidant polyphenols characterised by chemical profiling of leaf, flower and fruit.
Contribute to the vasoactive and antioxidant effects, the basis for extract standardisation.
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
inferred from antidiabetic action
inferred from anticancer action
inferred from antifungal action
inferred from anti-inflammatory action
inferred from antidiabetic action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from anticancer action
inferred from anti-inflammatory action
inferred from sedative action
Safety, Cautions & Contraindications
True cinnamon (C. verum) is safe in culinary and moderate medicinal doses. Cassia (C. cassia) contains high coumarin — excessive intake may be hepatotoxic and should not be confused with true cinnamon. May lower blood sugar — use caution with antidiabetic medications. Avoid high doses during pregnancy.
Duke (2002) rates Ceylon cinnamon as +++ and provides clinical evidence (score 2) for antibacterial activity, consistent with Commission E and WHO recognition. Key activities include antifungal (anti-Candida), antispasmodic, and carminative effects. Cinnamon contains cinnamaldehyde, eugenol, and coumarin. Important safety concern: Duke's entry aggregates true cinnamon (C. verum) and cassia (C. cassia) — cassia contains significantly higher coumarin levels (potentially hepatotoxic) than true Ceylon cinnamon. True cinnamon (C. verum) has very low coumarin content and is safe at normal culinary doses. Medicinal dose: 0.5–1 g bark powder three times daily. Caution: cinnamon bark oil is highly irritating to mucous membranes (Duke, 2002).
Generally well tolerated. Hawthorn should not replace prescribed cardiac medications without medical supervision. May potentiate the effects of cardiac glycosides (digoxin), antihypertensive drugs, and coronary dilators. Not recommended during pregnancy and breastfeeding due to insufficient safety data. Mild side effects (nausea, dizziness, GI upset) occasionally reported.
Duke (2002) rates hawthorn as +++ — one of the most clinically supported cardiovascular herbs. Clinical evidence (score 2) supports its use for decreasing cardiac output (NYHA functional Stage II heart failure), as recognized by Commission E. Key activities include vasodilation, positive inotropic effects, and antioxidant protection of vascular tissue. Dose: 160–900 mg standardized leaf/flower extract (containing 18.75% oligomeric proanthocyanidins) daily. Duke emphasizes that hawthorn should not replace conventional heart failure therapy, and therapeutic effects may take 4–8 weeks to emerge. Mild interactions with cardiac glycosides (digitalis) are possible (Duke, 2002).
External Ids
Botanical Description
Evergreen tree with smooth, thin, light brown bark and leathery, oval leaves with three prominent longitudinal veins, often flushed reddish-pink when young. Small, pale yellow-green flowers are borne in panicles, followed by small, dark, single-seeded berries. The thin inner bark is peeled and dried into the characteristic pale, tightly layered, multi-ply quills of true cinnamon.
Small deciduous tree or large shrub, densely thorny, with deeply lobed, glossy leaves (more deeply cut than midland hawthorn). Clusters of small, five-petalled white flowers with a strong, musky scent appear in spring ('May blossom'), followed by small red berries (haws), each containing a single seed (nutlet) - the origin of the species name monogyna.[4]
Habitat
Native to Sri Lanka and the Malabar coast of southern India; cultivated in warm, humid tropical lowlands, especially Sri Lanka, which remains the main source of true (Ceylon) cinnamon.
One of the commonest hedgerow and scrub trees of Europe, growing in hedgerows, woodland edges, scrub and pasture on a wide range of soils; native to Europe, North Africa and Western Asia.[4]
Harvesting
Young shoots are cut back to encourage thin, straight new growth; the thin outer bark is scraped away and the paper-thin inner bark is peeled off, dried and rolled by hand into the characteristic multi-layered quills of Ceylon cinnamon.
Flowers are picked as they open in May, leaves are picked with the young flowering shoots, and the ripe red berries (haws) are gathered in autumn after the first frosts soften them slightly; all three parts are traditionally combined.[4]
Traditional Uses
True cinnamon bark has an ancient trade and medicinal history across Asia, the Middle East and Europe as a warming digestive and circulatory remedy, used for indigestion and as a general tonic spice; because it contains only trace coumarin, it is considered the safer species for frequent or medicinal use compared with cassia.[8]
Common hawthorn shares the same long cardiovascular and calming tradition as midland hawthorn, used across European herbal medicine as a heart tonic for mild circulatory complaints, palpitations and nervous tension, and remains one of the most clinically studied cardiovascular botanicals.[4]
Preparations
Dried bark powder or standardised extract taken as capsules for metabolic and antioxidant support.
Comminuted bark infused in hot water as a herbal tea, 0.5-1 g up to four times daily per the EU herbal monograph. The monograph describes an infusion; it does not cover a simmered decoction. Educational reference only, not a prescription.
Leaf-and-flower extract standardised to flavonoid or procyanidin content, taken as tablets or capsules; the best-studied clinical form.
Dosage
The EU herbal monograph on Cinnamomum verum J.S. Presl, cortex gives, for adults and elderly, 0.5-1 g of the comminuted bark as an infusion up to 4 times daily; a liquid extract at 0.5-1 mL three times daily and a tincture at a daily dose of 2-4 mL are also listed. Not recommended under 18 years, and a practitioner should be consulted if symptoms persist beyond 2 weeks. Note this is Ceylon cinnamon (C. verum); cassia species carry a much higher coumarin load and are not covered here. Educational reference only, not a prescription.
The EU herbal monograph on Crataegus spp., folium cum flore gives dry extracts in divided daily doses of 240-900 mg (single dose 80-450 mg) or, for one quantified extract, 570-1750 mg daily (single dose 190-350 mg), in adults and elderly. If symptoms persist longer than 2 weeks a doctor should be consulted, and hawthorn is never used as a substitute for prescribed heart medication without medical supervision. Educational reference only, not a prescription.
The EU herbal monograph gives 1-2 g of the comminuted leaf and flower in 150 mL of boiling water as an infusion, up to 4 times daily (maximum 6 g daily), in adults and elderly. Educational reference only, not a prescription.
References
Drug Class Interactions
Pairings
Cinnamon and fenugreek can each lower blood sugar, so taking them together — especially alongside diabetes medicines — may add up and increase the risk of blood sugar dropping too low (hypoglycaemia). Monitor your blood glucose.[18, 19]
Cinnamon and bitter melon can each lower blood sugar, so taking them together — especially alongside diabetes medicines — may add up and increase the risk of hypoglycaemia. Monitor your blood glucose.[18, 20]
Not documented
Lookalikes Review
References & Sources
- Muthukuda, D. and de Silva, C.K. and Ajanthan, S. and Wijesinghe, N. and Dahanayaka, A. and Pathmeswaran, A (2025) 'Effects of Cinnamomum zeylanicum (Ceylon cinnamon) extract on lipid profile, glucose levels and its safety in adults: A randomized, double-blind, controlled trial', PLoS One, 20(1), pp. e0317904. doi:10.1371/journal.pone.0317904 Clinical study
https://doi.org/10.1371/journal.pone.0317904 - Singh, N. and Rao, A.S. and Nandal, A. and Kumar, S. and Yadav, S.S. and Ganaie, S.A. and Narasimhan, B (2020) 'Phytochemical and pharmacological review of Cinnamomum verum J. Presl - a versatile spice used in food and nutrition', Food Chemistry, 338, pp. 127773. doi:10.1016/j.foodchem.2020.127773 Meta-analysis / review
https://doi.org/10.1016/j.foodchem.2020.127773 - Kim, N.Y. and Kim, S. and Park, H.M. and Lim, C.M. and Kim, J. and Park, J.Y. and Jeon, K.B. and Poudel, A (2023) 'Cinnamomum verum extract inhibits NOX2/ROS and PKCdelta/JNK/AP-1/NF-kB pathway-mediated inflammatory response in PMA-stimulated THP-1 monocytes', Phytomedicine, 112, pp. 154685. doi:10.1016/j.phymed.2023.154685 Preclinical
https://doi.org/10.1016/j.phymed.2023.154685 - Pagliari, S. and Forcella, M. and Lonati, E. and Sacco, G. and Romaniello, F. and Rovellini, P. and Fusi, P. and Palestini, P (2023) 'Antioxidant and Anti-Inflammatory Effect of Cinnamon (Cinnamomum verum J. Presl) Bark Extract after In Vitro Digestion Simulation', Foods, 12(3), pp. 452. doi:10.3390/foods12030452 Preclinical
https://doi.org/10.3390/foods12030452 - Ul Hasnain, S.Z. and Ahmed, M. and Manzoor, R. and Amin, A. and Mudassir, J. and Jafar Rana, S. and Abbas, K (2024) 'Anti-inflammatory, antidiabetic and hypolipidemic potential of Cinnamomum verum J. Presl bark coupled with FT-IR and HPLC analysis', Pakistan Journal of Pharmaceutical Sciences, 37(6), pp. 1529-1544. Preclinical
https://scholar.google.com/scholar?q=Anti-inflammatory%2C%20antidiabetic%20and%20hypolipidemic%20potential%20of%20Cinnamomum%20verum%20J.%20Presl%20bark%20coupled%20with%20FT-IR%20and%20HPLC%20analysis - Gu, K., Feng, S., Zhang, X., Peng, Y., Sun, P., Liu, W., Wu, Y., Yu, Y., Liu, X., Deng, G., Zheng, J., Li, B. and Zhao, L (2023) 'Deciphering the antifungal mechanism and functional components of Cinnamomum cassia essential oil against Candida albicans', Journal of Ethnopharmacology, pp. 2023. doi:10.1016/j.jep.2023.117156 Preclinical
https://doi.org/10.1016/j.jep.2023.117156 - Aggarwal, S., Bhadana, K., Singh, B., Rawat, M., Mohammad, T., Al-Keridis, L.A., Alshammari, N., Hassan, M.I. and Das, S.N (2022) 'Cinnamomum zeylanicum extract and its bioactive component cinnamaldehyde show anti-tumor effects via inhibition of multiple cellular pathways', Frontiers in Pharmacology. doi:10.3389/fphar.2022.918479 Preclinical
https://doi.org/10.3389/fphar.2022.918479 - Groves, M (2016) 'Body into Balance'. Traditional / reference
https://scholar.google.com/scholar?q=Body%20into%20Balance - European Medicines Agency (HMPC) (2011) 'Community herbal monograph on Cinnamomum verum J.S. Presl, cortex'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/community-herbal-monograph-cinnamomum-verum-js-presl-cortex_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-monograph/community-herbal-monograph-cinnamomum-verum-js-presl-cortex_en.pdf - Jafari, A., Mardani, H., Faghfouri, A.H., AhmadianMoghaddam, M., Musazadeh, V. and Alaghi, A (2025) 'The effect of cinnamon supplementation on cardiovascular risk factors in adults: a GRADE assessed systematic review, dose-response and meta-analysis of randomized controlled trials', Journal of Health, Population and Nutrition, 44(1). doi:10.1186/s41043-025-00967-3 Meta-analysis / review
https://doi.org/10.1186/s41043-025-00967-3 - Akilen, R. et al (2010) 'Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK', 27(10), pp. 1159--1167. Clinical study
https://scholar.google.com/scholar?q=Glycated%20haemoglobin%20and%20blood%20pressure-lowering%20effect%20of%20cinnamon%20in%20multi-ethnic%20Type%202%20diabetic%20patients%20in%20the%20UK - Khan, A. et al (2003) 'Cinnamon improves glucose and lipids of people with type 2 diabetes', 26(12), pp. 3215--3218. doi:10.2337/diacare.26.12.3215 Traditional / reference
https://doi.org/10.2337/diacare.26.12.3215 - Moridpour, A.H., Kavyani, Z., Khosravi, S., Farmani, E., Daneshvar, M., Musazadeh, V. and Faghfouri, A.H (2023) 'The effect of cinnamon supplementation on glycemic control in patients with type 2 diabetes mellitus: An updated systematic review and dose-response meta-analysis of randomized controlled trials', Phytotherapy Research, 38(1), pp. 117--130. doi:10.1002/ptr.8026 Meta-analysis / review
https://doi.org/10.1002/ptr.8026 - de Moura, S.L., Gomes, B.G.R., Guilarducci, M.J., Coelho, O.G.L., Guimaraes, N.S. and Gomes, J.M.G (2025) 'Effects of cinnamon supplementation on metabolic biomarkers in individuals with type 2 diabetes: a systematic review and meta-analysis', Nutrition Reviews, 83(2), pp. 249--279. doi:10.1093/nutrit/nuae058 Meta-analysis / review
https://doi.org/10.1093/nutrit/nuae058 - Maierean, S.M., Serban, M.C., Sahebkar, A., Ursoniu, S., Serban, A., Penson, P. and Banach, M (2017) 'The effects of cinnamon supplementation on blood lipid concentrations: A systematic review and meta-analysis', Journal of Clinical Lipidology, 11(6), pp. 1393--1406. doi:10.1016/j.jacl.2017.08.004 Meta-analysis / review
https://doi.org/10.1016/j.jacl.2017.08.004 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Allen, R.W., Schwartzman, E., Baker, W.L., Coleman, C.I. and Phung, O.J (2013) 'Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis', Annals of Family Medicine, 11(5), pp. 452-459. doi:10.1370/afm.1517 Meta-analysis / review
https://doi.org/10.1370/afm.1517 - de Moura, S.L., Gomes, B.G.R., Guilarducci, M.J., Coelho, O.G.L., Guimaraes, N.S. and Gomes, J.M.G (2025) 'Effects of cinnamon supplementation on metabolic biomarkers in individuals with type 2 diabetes: a systematic review and meta-analysis', Nutrition Reviews, 83(2), pp. 249-279. doi:10.1093/nutrit/nuae058 Meta-analysis / review
https://doi.org/10.1093/nutrit/nuae058 - Kim, J., Noh, W., Kim, A., Choi, Y. and Kim, Y.S (2023) 'The effect of fenugreek in type 2 diabetes and prediabetes: a systematic review and meta-analysis of randomized controlled trials', International Journal of Molecular Sciences, 24(18), pp. 13999. doi:10.3390/ijms241813999 Meta-analysis / review
https://doi.org/10.3390/ijms241813999 - Zhang, X., Zhao, Y., Song, Y. and Miao, M (2024) 'Effects of Momordica charantia L. supplementation on glycemic control and lipid profile in type 2 diabetes mellitus patients: a systematic review and meta-analysis of randomized controlled trials', Heliyon, 10(10), pp. e31126. doi:10.1016/j.heliyon.2024.e31126 Meta-analysis / review
https://doi.org/10.1016/j.heliyon.2024.e31126
- Ez-Zahra Amrati, F., Mssillou, I., Boukhira, S., Djiddi Bichara, M. et al (2024) 'Phenolic Composition of Crataegus monogyna Jacq. Extract and Its Anti-Inflammatory, Hepatoprotective, and Antileukemia Effects', Pharmaceuticals (Basel), 17(6), pp. 786. doi:10.3390/ph17060786 Preclinical
https://doi.org/10.3390/ph17060786 - Lis, M., Szczypka, M., Suszko-Pawłowska, A., Sokół-Łętowska, A. et al (2019) 'Hawthorn (Crataegus monogyna) Phenolic Extract Modulates Lymphocyte Subsets and Humoral Immune Response in Mice', Planta Medica, 86(2), pp. 160-168. doi:10.1055/a-1045-5437 Preclinical
https://doi.org/10.1055/a-1045-5437 - Paun, G., Neagu, E., Albu, C., Alecu, A. et al (2024) 'Antioxidant and Antidiabetic Activity of Crataegus monogyna L. and Cornus mas Fruit Extracts', Molecules, 29(15), pp. 3595. doi:10.3390/molecules29153595 Preclinical
https://doi.org/10.3390/molecules29153595 - Nabavi, S.F., Habtemariam, S., Ahmed, T., Sureda, A., Daglia, M. and Sobarzo-Sanchez, E (2015) 'Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications', Nutrients, 7(9), pp. 7708-7728. doi:10.3390/nu7095361 Meta-analysis / review
https://doi.org/10.3390/nu7095361 - Belabdelli, F., Bekhti, N., Piras, A., Benhafsa, F.M., Ilham, M. and Adil, S (2021) 'Chemical composition, antioxidant and antibacterial activity of Crataegus monogyna leaves' extracts', Natural Product Research, 36(12), pp. 3234-3239. doi:10.1080/14786419.2021.1958215 Preclinical
https://doi.org/10.1080/14786419.2021.1958215 - Jalali, A.S., Hasanzadeh, S. and Malekinejad, H (2012) 'Crataegus monogyna aqueous extract ameliorates cyclophosphamide-induced toxicity in rat testis: stereological evidences', Acta Medica Iranica, 50(1), pp. 1-8. Preclinical
https://scholar.google.com/scholar?q=Crataegus%20monogyna%20aqueous%20extract%20ameliorates%20cyclophosphamide-induced%20toxicity%20in%20rat%20testis%3A%20stereological%20evidences - Martin-Garcia, B., Razola-Diaz, M.D.C., Gomez-Caravaca, A.M., Benitez, G. and Verardo, V (2021) 'Setup of an Ultrasonic-Assisted Extraction to Obtain High Phenolic Recovery in Crataegus monogyna Leaves', Molecules, 26(15), pp. 4536. doi:10.3390/molecules26154536 Preclinical
https://doi.org/10.3390/molecules26154536 - Arslan, R., Bektas, N., Bor, Z. and Sener, E (2014) 'Evaluation of the antithrombotic effects of Crataegus monogyna and Crataegus davisii in the carrageenan-induced tail thrombosis model', Pharmaceutical Biology, 53(2), pp. 275-279. doi:10.3109/13880209.2014.914957 Preclinical
https://doi.org/10.3109/13880209.2014.914957 - Edwards, J.E., Brown, P.N., Talent, N., Dickinson, T.A. and Shipley, P.R (2012) 'A review of the chemistry of the genus Crataegus', Phytochemistry, 79, pp. 5-26. doi:10.1016/j.phytochem.2012.04.006 Meta-analysis / review
https://doi.org/10.1016/j.phytochem.2012.04.006 - Jarzycka, A., Lewinska, A., Gancarz, R. and Wilk, K.A (2013) 'Assessment of extracts of Helichrysum arenarium, Crataegus monogyna, Sambucus nigra in photoprotective UVA and UVB; photostability in cosmetic emulsions', Journal of Photochemistry and Photobiology B: Biology, 128, pp. 50-57. doi:10.1016/j.jphotobiol.2013.07.029 Preclinical
https://doi.org/10.1016/j.jphotobiol.2013.07.029 - Lucconi, G., Chlapanidas, T., Martino, E., Gaggeri, R., Perteghella, S. and Rossi, D (2013) 'Formulation of microspheres containing Crataegus monogyna Jacq. extract with free radical scavenging activity', Pharmaceutical Development and Technology, 19(1), pp. 65-72. doi:10.3109/10837450.2012.752387 Preclinical
https://doi.org/10.3109/10837450.2012.752387 - Zorniak, M., Szydlo, B. and Krzeminski, T.F (2017) 'Crataegus special extract WS 1442: up-to-date review of experimental and clinical experiences', Journal of Physiology and Pharmacology, 68(4), pp. 521-526. Meta-analysis / review
https://scholar.google.com/scholar?q=Crataegus%20special%20extract%20WS%201442%3A%20up-to-date%20review%20of%20experimental%20and%20clinical%20experiences - European Medicines Agency (2016) 'European Union herbal monograph on Crataegus spp., folium cum flore'. Traditional / reference
https://scholar.google.com/scholar?q=European%20Union%20herbal%20monograph%20on%20Crataegus%20spp.%2C%20folium%20cum%20flore - Pittler, M.H., Guo, R. and Ernst, E (2008) 'Hawthorn extract for treating chronic heart failure'. Traditional / reference
https://scholar.google.com/scholar?q=Hawthorn%20extract%20for%20treating%20chronic%20heart%20failure - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Tankanow, R., Tamer, H.R., Streetman, D.S., Smith, S.G., Welton, J.L., Annesley, T., Aaronson, K.D. and Bleske, B.E (2003) 'Interaction study between digoxin and a preparation of hawthorn (Crataegus oxyacantha)', Journal of Clinical Pharmacology, 43(6), pp. 637-642. doi:10.1177/0091270003253417 Randomized trial
https://doi.org/10.1177/0091270003253417 - Pittler, M.H., Guo, R. and Ernst, E (2008) 'Hawthorn extract for treating chronic heart failure', Cochrane Database of Systematic Reviews, 2008(1), pp. CD005312. doi:10.1002/14651858.CD005312.pub2 Meta-analysis / review
https://doi.org/10.1002/14651858.CD005312.pub2 - Pittler, M.H., Guo, R. and Ernst, E (2008) 'Hawthorn extract for treating chronic heart failure', Cochrane Database of Systematic Reviews, 2008(1), pp. CD005312. doi:10.1002/14651858.CD005312.pub2 Meta-analysis / review
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.