Plant Comparison

Centaury vs Breckland Thyme

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
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Plant ACentauryCentaurium erythraeaGentianaceaeFull monograph →
Plant BBreckland ThymeThymus serpyllumLamiaceaeFull monograph →

At a glance

Centaury and Breckland Thyme: they share 5 indicated uses (acid reflux, arthritis / joint pain, indigestion, …); 2 pharmacological actions in common.

CentauryBreckland Thyme
Constituents33
Pharmacological actions55
Indicated uses99
Safety notes22
Cited sources1414
Indicated uses
Only Centaury
Loss of appetiteBloatingDetox / cleansingLiver support
Shared (5)
Acid refluxArthritis / joint painIndigestionInflammation (general)Skin irritation
Only Breckland Thyme
Cancer (anticancer research)Infection (general)Respiratory supportWounds
Pharmacological actions
Only Centaury
Bitter digestive tonic / stomachicDigestive aidHepatoprotective (liver support)
Shared (2)
Anti-inflammatoryGastroprotective
Only Breckland Thyme
Anticancer (preclinical)AntimicrobialAntioxidant

Evidence face-off — shared uses

ConditionCentauryBreckland ThymeVerdict
Acid reflux1/101/10Comparable evidence
Arthritis / joint pain1/101/10Comparable evidence
Indigestion1/101/10Comparable evidence
Inflammation (general)1/101/10Comparable evidence
Skin irritation1/101/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Secoiridoid bitter glycosides (gentiopicroside, swertiamarin, sweroside, centapicrin)[12, 13]

The intensely bitter principles that stimulate digestive secretions.

Glycosides
Xanthones and flavonoids[12, 13]

Additional constituents of the herb.

Flavonoids
Phenolic acids[12]

Antioxidant constituents.

Phenolic acids
Essential oil (thymol, carvacrol, p-cymene)[2]

The volatile oil, dominated by thymol and carvacrol, gives most of the antimicrobial and antioxidant activity.

Essential (volatile) oilThymolCarvacrolTerpenes / terpenoids
Phenolic acids and flavonoids (rosmarinic acid, luteolin)[3]

Contribute additional antioxidant activity.

Rosmarinic acidPhenolic acidsFlavonoidsLuteolin
Triterpenes (ursolic acid, oleanolic acid)[1]

Minor constituents studied for anti-inflammatory activity.

Pharmacological Actions

Anti-inflammatory[4, 12, 13]

Digestive aid for mild dyspeptic complaints such as indigestion and bloating (stimulates gastric and bile secretion) - a comprehensive review also documents gastroprotective, hepatoprotective and anti-inflammatory activity

Bitter digestive tonic / stomachic[4, 9, 12, 13]

Aromatic bitter tonic for temporary loss of appetite

Digestive aid[1, 4, 5, 12, 13]

Digestive aid for mild dyspeptic complaints such as indigestion and bloating (stimulates gastric and bile secretion) - a comprehensive review also documents gastroprotective, hepatoprotective and anti-inflammatory activity

Gastroprotective[1, 4, 12, 13]

Digestive aid for mild dyspeptic complaints such as indigestion and bloating (stimulates gastric and bile secretion) - a comprehensive review also documents gastroprotective, hepatoprotective and anti-inflammatory activity

Hepatoprotective (liver support)[4, 12, 13]

Digestive aid for mild dyspeptic complaints such as indigestion and bloating (stimulates gastric and bile secretion) - a comprehensive review also documents gastroprotective, hepatoprotective and anti-inflammatory activity

Anti-inflammatory[1, 6, 11, 12, 13]
Anticancer (preclinical)[9]
Antimicrobial[1, 4, 5, 6, 11, 12, 13]
Antioxidant[1, 2, 3, 4, 6, 11, 12, 13]
Gastroprotective[11, 12, 13]

Traditional & Indicated Uses

Acid reflux[4, 12, 13]Traditional · 1/10

inferred from gastroprotective action

Evidence: 1
Label: Acid reflux
Loss of appetite[12, 13]Traditional · 1/10

Aromatic bitter tonic for temporary loss of appetite

Evidence: 1
Label: Loss of appetite
Arthritis / joint pain[4, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Bloating[4, 12, 13]Traditional · 1/10

Digestive aid for mild dyspeptic complaints such as indigestion and bloating (stimulates gastric and bile secretion) - a comprehensive review also documents gastroprotective, hepatoprotective and anti-inflammatory activity

Evidence: 1
Label: Bloating
Detox / cleansing[4, 12, 13]Traditional · 1/10

inferred from hepatoprotective action

Evidence: 1
Label: Detox / cleansing
Indigestion[4, 12, 13]Traditional · 1/10

Digestive aid for mild dyspeptic complaints such as indigestion and bloating (stimulates gastric and bile secretion) - a comprehensive review also documents gastroprotective, hepatoprotective and anti-inflammatory activity

Evidence: 1
Label: Indigestion
Inflammation (general)[4, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Liver support[4, 12, 13]Traditional · 1/10

inferred from hepatoprotective action

Evidence: 1
Label: Liver support
Skin irritation[4, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Acid reflux[11, 12, 13]Traditional · 1/10

inferred from gastroprotective action

Evidence: 1
Label: Acid reflux
Arthritis / joint pain[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Cancer (anticancer research)[9]Traditional · 2/10

inferred from anticancer action

Evidence: 2
Label: Cancer (anticancer research)
Indigestion[11, 12, 13]Traditional · 1/10

inferred from gastroprotective action

Evidence: 1
Label: Indigestion
Infection (general)[11, 12, 13]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Respiratory support[11, 12, 13]Traditional · 1/10
Evidence: 1
Label: Respiratory support
Skin irritation[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[11, 12, 13]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds

Safety, Cautions & Contraindications

Safety note[12]Caution

Because bitters increase stomach-acid secretion, centaury is contraindicated in peptic (stomach or duodenal) ulcer disease and hyperacidity.

Safety note[12]Caution

Traditional use only; appetite loss or dyspepsia that persists needs medical assessment. Use during pregnancy and breastfeeding is not recommended.

Safety note[11, 12, 13]Caution

Generally safe at culinary doses. Essential oil is highly concentrated and must be diluted before topical use; undiluted application can cause skin sensitisation. Not recommended internally during pregnancy (uterine stimulant effects possible). Phenol-rich thyme preparations should be avoided long-term in high doses. May potentiate anticoagulant medications.

Safety note[11, 12, 13, 14]Info

Duke (2002) rates Thymus vulgaris (garden thyme, closely related to breckland thyme) as +++ with clinical evidence (score 2) for antibacterial, bronchospasmolytic, and antispasmodic activities, consistent with Commission E and WHO approvals for bronchitis and upper respiratory catarrh. The primary active constituent is thymol, with carvacrol as a secondary compound. Dose: 1–2 g dried herb as tea three times daily. The plant demonstrates COX-2 inhibitory activity and calcium antagonism, which may explain its antispasmodic effects (Duke, 2002).

External Ids

Gbif: 5414457
Wikidata: Q156870
Gbif: 6409622
Wikidata: Q147251

Botanical Description

Slender annual or biennial herb with a basal rosette of oval leaves and an erect, wiry, four-angled flowering stem branching near the top. Small, star-shaped, pink flowers with five pointed petals open only in sunshine, borne in dense, flat-topped clusters at the stem tips.[12]

Height: 10-40 cm
Habit: Slender, erect annual to biennial herb
Leaves: Basal rosette of oval leaves; stem leaves smaller, opposite
Flowers: Small, star-shaped, pink, five-petalled, opening only in sunshine, in flat-topped clusters
Stem: Erect, wiry, four-angled, branching near the top
Root: Slender taproot
Fruit: Small, narrow capsule
Flowering Period: June-September

Low, mat-forming, aromatic perennial subshrub with tiny, oval, strongly aromatic leaves on trailing, wiry, hairy stems that root as they spread. Small, pinkish-purple, two-lipped flowers are borne in dense whorled clusters at the stem tips.

Height: 2-10 cm (mat-forming, trailing)
Habit: Low, mat-forming, aromatic perennial subshrub
Leaves: Tiny, oval, strongly aromatic
Flowers: Small, pinkish-purple, two-lipped, in dense whorled terminal clusters
Stem: Trailing, wiry, hairy, rooting as it spreads
Root: Fine, fibrous roots along the creeping stem
Fruit: Small nutlet
Flowering Period: May-September

Habitat

Grows in dry grassland, chalk downland, dunes and open woodland on well-drained, often calcareous soils; native to Europe, North Africa and Western Asia.[12]

Grows on dry, sunny heath, grassland, rocky ground and sandy soils; native to Europe and widely distributed across the northern temperate zone.

Harvesting

The flowering aerial parts are cut in summer while in flower, when the intensely bitter secoiridoid content is highest, and dried in a warm, shaded, airy place.[12]

Parts: Aerial parts (flowering herb)
Season: Summer flowering period

The flowering aerial parts (flower and leaf) are cut at the start of flowering in summer and dried in a warm, shaded, airy place.

Parts: Flower, Leaf
Season: Summer, at start of flowering

Traditional Uses

Centaury is one of the classic European bitter digestive herbs, traditionally used for temporary loss of appetite and mild dyspeptic complaints such as indigestion and bloating, stimulating gastric and bile secretion.[12]

Wild thyme has a long European folk tradition, closely paralleling its relative garden thyme, as an antimicrobial and expectorant remedy for coughs and respiratory infections, a digestive/gastroprotective herb, and a topical antiseptic.[11, 12, 13]

Preparations

Cold infusion (maceration)[12]

Dried herb macerated in cold water for several hours, which extracts the bitter principles while minimising extraction of harsher tannins; a traditional preparation method for bitters.

Infusion[12]

Dried herb infused briefly in hot water and taken shortly before meals as a bitter digestive tonic.

Tincture[14]

Tincture of the dried herb; the EU herbal monograph gives 1.5-5 g up to three times daily. Educational reference only, not a prescription.

Infusion[12]

Dried flowering herb infused in hot water as a traditional respiratory and digestive tea.

Dosage

Infusion[12, 14]

The EU herbal monograph gives 1-4 g of the comminuted herb in 200 mL of boiling water as an infusion, up to 4 times daily, in adults and elderly; a powdered herbal substance at 0.25-2 g up to 3 times daily, liquid extract 2-4 mL up to 3 times daily, and tincture 1.5-5 g up to 3 times daily are also listed. Not recommended under 18 years, and contraindicated in peptic ulcer. Educational reference only, not a prescription.

Not documented

References

REF-0767, REF-0768, REF-0769, REF-0619, REF-1988, REF-1989, REF-1990, REF-1991, REF-1992, REF-1993, REF-1994
REF-1094, REF-1095, REF-1096, REF-1097, REF-1098, REF-1099, REF-1100, REF-1101, REF-1102, REF-1103

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Tuluce, Y., Ozkol, H., Koyuncu, I. and Ine, H (2011) 'Gastroprotective effect of small centaury (Centaurium erythraea L) on aspirin-induced gastric damage in rats', Toxicology and Industrial Health, 27(8), pp. 760-768. doi:10.1177/0748233710397421 Preclinical
    https://doi.org/10.1177/0748233710397421
  2. Chabane, S., Boudjelal, A., Bouaziz-Terrachet, S., Spinozzi, E. et al (2023) 'Analgesic effect of Centaurium erythraea and molecular docking investigation of the major component swertiamarin', Natural Product Research, 38(24), pp. 4511-4517. doi:10.1080/14786419.2023.2278160 Preclinical
    https://doi.org/10.1080/14786419.2023.2278160
  3. Akşit, H., Gözcü, S. and Altay, A (2022) 'Isolation and cytotoxic activities of undescribed iridoid and xanthone glycosides from Centaurium erythraea Rafn. (Gentianaceae)', Phytochemistry, 205, pp. 113484. doi:10.1016/j.phytochem.2022.113484 Preclinical
    https://doi.org/10.1016/j.phytochem.2022.113484
  4. El Menyiy, N., Guaouguaou, F.E., El Baaboua, A., El Omari, N., Taha, D. and others (2021) 'Phytochemical properties, biological activities and medicinal use of Centaurium erythraea Rafn', Journal of Ethnopharmacology, pp. 2021. doi:10.1016/j.jep.2021.114171 Traditional / reference
    https://doi.org/10.1016/j.jep.2021.114171
  5. Guedes, L., Reis, P.B.P.S., Machuqueiro, M., Ressaissi, A., Pacheco, R. and Serralheiro, M.L (2019) 'Bioactivities of Centaurium erythraea (Gentianaceae) Decoctions: Antioxidant Activity, Enzyme Inhibition and Docking Studies', Molecules, 24(20), pp. 3795. doi:10.3390/molecules24203795 Preclinical
    https://doi.org/10.3390/molecules24203795
  6. Dordevic, M., Mihailovic, M., Arambasic Jovanovic, J., Grdovic, N., Uskokovic, A., Tolic, A., Sinadinovic, M., Rajic, J., Misic, D., Siler, B., Poznanovic, G., Vidakovic, M. and Dinic, S (2017) 'Centaurium erythraea methanol extract protects red blood cells from oxidative damage in streptozotocin-induced diabetic rats', Journal of Ethnopharmacology, 202, pp. 172-183. doi:10.1016/j.jep.2017.03.016 Preclinical
    https://doi.org/10.1016/j.jep.2017.03.016
  7. Dordevic, M., Grdovic, N., Mihailovic, M., Arambasic Jovanovic, J., Uskokovic, A., Rajic, J., Sinadinovic, M., Tolic, A., Misic, D., Siler, B., Poznanovic, G., Vidakovic, M. and Dinic, S (2019) 'Centaurium erythraea extract improves survival and functionality of pancreatic beta-cells in diabetes through multiple routes of action', Journal of Ethnopharmacology, 242, pp. 112043. doi:10.1016/j.jep.2019.112043 Preclinical
    https://doi.org/10.1016/j.jep.2019.112043
  8. Chda, A., El Kabbaoui, M., Fresco, P., Silva, D., Goncalves, J., Oliveira, A.P., Andrade, P.B., Valentao, P., Tazi, A., El Abida, K. and Bencheikh, R (2019) 'Centaurium Erythraea Extracts Exert Vascular Effects through Endothelium- and Fibroblast-dependent Pathways', Planta Medica, 86(2), pp. 121-131. doi:10.1055/a-1023-8918 Preclinical
    https://doi.org/10.1055/a-1023-8918
  9. Kumarasamy, Y., Nahar, L., Cox, P.J., Jaspars, M. and Sarker, S.D (2003) 'Bioactivity of secoiridoid glycosides from Centaurium erythraea', Phytomedicine, 10(4), pp. 344-347. doi:10.1078/094471103322004857 Preclinical
    https://doi.org/10.1078/094471103322004857
  10. Kachmar, M.R., Oliveira, A.P., Valentao, P., Gil-Izquierdo, A., Dominguez-Perles, R., Ouahbi, A., Badaoui, K.E., Andrade, P.B. and Ferreres, F (2018) 'HPLC-DAD-ESI/MS phenolic profile and in vitro biological potential of Centaurium erythraea Rafn aqueous extract', Food Chemistry, 278, pp. 424-433. doi:10.1016/j.foodchem.2018.11.082 Preclinical
    https://doi.org/10.1016/j.foodchem.2018.11.082
  11. Mandova, T., Audo, G., Michel, S. and Grougnet, R (2017) 'Off-line coupling of new generation centrifugal partition chromatography device with preparative high pressure liquid chromatography-mass spectrometry triggering fraction collection applied to the recovery of secoiridoid glycosides from Centaurium erythraea Rafn. (Gentianaceae)', Journal of Chromatography A, 1513, pp. 149-156. doi:10.1016/j.chroma.2017.07.023 Preclinical
    https://doi.org/10.1016/j.chroma.2017.07.023
  12. European Medicines Agency (HMPC) (n.d.) 'Assessment report on Centaurium erythraea Rafn s.l., herba (Centaurii herba)'. Available at: https://www.ema.europa.eu/en/documents/herbal-report/assessment-report-centaurium-erythraea-rafn-sl-herba_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/herbal-report/assessment-report-centaurium-erythraea-rafn-sl-herba_en.pdf
  13. Herbal Reality (n.d.) 'Centaury (Centaurium erythraea): Benefits, Safety, Uses'. Available at: https://www.herbalreality.com/herb/centaury/ Traditional / reference
    https://www.herbalreality.com/herb/centaury/
  14. European Medicines Agency (HMPC) (2015) 'European Union herbal monograph on Centaurium erythraea Rafn s.l., herba (Centaurii herba)'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/european-union-herbal-monograph-centaurium-erythraea-rafn-sl-herba_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/herbal-monograph/european-union-herbal-monograph-centaurium-erythraea-rafn-sl-herba_en.pdf
  1. Jalil, B., Pischel, I., Feistel, B., Suarez, C. and others (2024) 'Wild thyme (Thymus serpyllum L.): a review of the current evidence of nutritional and preventive health benefits', Frontiers in Nutrition, 11, pp. 1380962. doi:10.3389/fnut.2024.1380962 Meta-analysis / review
    https://doi.org/10.3389/fnut.2024.1380962
  2. Sonmezdag, A.S., Kelebek, H. and Selli, S (2016) 'Characterization of aroma-active and phenolic profiles of wild thyme (Thymus serpyllum) by GC-MS-Olfactometry and LC-ESI-MS/MS', Journal of Food Science and Technology, 53(4), pp. 1957-1965. doi:10.1007/s13197-015-2144-1 Preclinical
    https://doi.org/10.1007/s13197-015-2144-1
  3. Pavlic, B., Mrkonjic, Z., Teslic, N., Kljakic, A.C. and others (2022) 'Natural Deep Eutectic Solvent (NADES) Extraction Improves Polyphenol Yield and Antioxidant Activity of Wild Thyme (Thymus serpyllum L.) Extracts', Molecules, 27(5), pp. 1508. doi:10.3390/molecules27051508 Preclinical
    https://doi.org/10.3390/molecules27051508
  4. Mrkonjic, Z., Kaplan, M., Milosevic, S., Bozovic, D. and others (2024) 'Green Extraction Approach for Isolation of Bioactive Compounds in Wild Thyme (Thymus serpyllum L.) Herbal Dust-Chemical Profile, Antioxidant and Antimicrobial Activity and Comparison with Conventional Techniques', Plants, 13(6), pp. 897. doi:10.3390/plants13060897 Preclinical
    https://doi.org/10.3390/plants13060897
  5. Sokolic-Mihalak, D., Frece, J., Slavica, A., Delas, F. and others (2012) 'The effects of wild thyme (Thymus serpyllum L.) essential oil components against ochratoxin-producing Aspergilli', Arhiv za Higijenu Rada i Toksikologiju, 63(4), pp. 457-462. doi:10.2478/10004-1254-63-2012-2309 Preclinical
    https://doi.org/10.2478/10004-1254-63-2012-2309
  6. Jaric, S., Mitrovic, M. and Pavlovic, P (2015) 'Review of Ethnobotanical, Phytochemical, and Pharmacological Study of Thymus serpyllum L', Evidence-Based Complementary and Alternative Medicine, 2015, pp. 101978. doi:10.1155/2015/101978 Meta-analysis / review
    https://doi.org/10.1155/2015/101978
  7. Loziene, K., Vaiciuniene, J. and Venskutonis, P.R (1998) 'Chemical composition of the essential oil of creeping thyme (Thymus serpyllum s.l.) growing wild in Lithuania', Planta Medica, 64(8), pp. 772-773. doi:10.1055/s-2006-957582 Preclinical
    https://doi.org/10.1055/s-2006-957582
  8. Raal, A., Paaver, U., Arak, E. and Orav, A (2004) 'Content and composition of the essential oil of Thymus serpyllum L. growing wild in Estonia', Medicina (Kaunas), 40(8), pp. 795-800. Preclinical
    https://scholar.google.com/scholar?q=Content%20and%20composition%20of%20the%20essential%20oil%20of%20Thymus%20serpyllum%20L.%20growing%20wild%20in%20Estonia
  9. Bozkurt, E., Atmaca, H., Kisim, A., Uzunoglu, S. and others (2012) 'Effects of Thymus serpyllum extract on cell proliferation, apoptosis and epigenetic events in human breast cancer cells', Nutrition and Cancer, 64(8), pp. 1245-1250. doi:10.1080/01635581.2012.719658 Preclinical
    https://doi.org/10.1080/01635581.2012.719658
  10. Jovanovic, A.A., Levic, S.M., Pavlovic, V.B., Markovic, S.B. and others (2021) 'Freeze vs. Spray Drying for Dry Wild Thyme (Thymus serpyllum L.) Extract Formulations: The Impact of Gelatin as a Coating Material', Molecules, 26(13), pp. 3933. doi:10.3390/molecules26133933 Preclinical
    https://doi.org/10.3390/molecules26133933
  11. European Medicines Agency (2010) 'Assessment report on Thymus vulgaris L., herba and Thymus zygis L., herba'. Traditional / reference
    https://scholar.google.com/scholar?q=Assessment%20report%20on%20Thymus%20vulgaris%20L.%2C%20herba%20and%20Thymus%20zygis%20L.%2C%20herba
  12. Kempe, K., Doerfler, G., Bader, D. and Wicht, M (2011) 'Activity of Thymus serpyllum against oral pathogens', 9(1), pp. 23--28. Traditional / reference
    https://scholar.google.com/scholar?q=Activity%20of%20Thymus%20serpyllum%20against%20oral%20pathogens
  13. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
    https://powo.science.kew.org
  14. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.