Plant Comparison

Tea vs Selfheal

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ATeaCamellia sinensisTheaceaeFull monograph →
Plant BSelfhealPrunella vulgarisLamiaceaeFull monograph →

At a glance

Tea and Selfheal: they share 9 indicated uses (arthritis / joint pain, blood sugar / diabetes support, cancer (anticancer research), …); 6 pharmacological actions in common.

TeaSelfheal
Constituents32
Pharmacological actions610
Indicated uses1112
Safety notes22
Cited sources2137
Indicated uses
Only Tea
MemoryMetabolic support
Shared (9)
Arthritis / joint painBlood sugar / diabetes supportCancer (anticancer research)Cardiovascular / heart healthCognitive functionInfection (general)Inflammation (general)Skin irritationWounds
Only Selfheal
BruisingCold & fluImmune support
Pharmacological actions
Only Tea
none
Shared (6)
Anti-inflammatoryAnticancer (preclinical)Antidiabetic (blood-sugar lowering)AntimicrobialAntioxidantNeuroprotective / cognition support
Only Selfheal
AntiviralImmunomodulator / immune supportVulnerary (wound healing)Hepatoprotective (liver support)

Evidence face-off — shared uses

ConditionTeaSelfhealVerdict
Arthritis / joint pain1/102/10Comparable evidence
Blood sugar / diabetes support1/102/10Comparable evidence
Cancer (anticancer research)8/107/10Comparable evidence
Cardiovascular / heart health1/102/10Comparable evidence
Cognitive function1/102/10Comparable evidence
Infection (general)1/102/10Comparable evidence
Inflammation (general)1/102/10Comparable evidence
Skin irritation1/102/10Comparable evidence
Wounds1/102/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Catechins (EGCG, ECG) and polyphenols[1, 15]

Principal antioxidant polyphenols, most concentrated in minimally oxidised green tea; epigallocatechin gallate (EGCG) is the best studied.

CatechinsPhenolic compounds
Caffeine and theanine[1]

Caffeine gives tea its mild stimulant effect; L-theanine, a unique amino acid, is associated with calm alertness and modulates caffeine's effects.

Caffeine
Theaflavins and thearubigins[15]

Oxidative polymerisation products of catechins formed during black tea processing, contributing to black tea's colour and its own antioxidant profile.

Triterpenoids and phenolic acids[1, 3]

Pentacyclic triterpenoids (ursolic, oleanolic and betulinic acids), the phenolic acid rosmarinic acid, coumarins (umbelliferone, scopoletin, esculetin) and the flavonoid luteolin are the main bioactives behind self-heal's antioxidant, anti-inflammatory and antimicrobial activity.

Rosmarinic acidPhenolic acidsCoumarinsFlavonoidsLuteolin
Sulphated and polyphenol-conjugated polysaccharides[4, 29, 30, 31]

Water-extracted polysaccharides — including a partially sulphated arabinogalactomannan (PSP-2B) and polyphenolic-protein-polysaccharide conjugates (PVG/PVE30) — are the principal antiviral and immunomodulatory constituents, blocking herpes simplex virus attachment and modulating innate immune signalling.

PolysaccharidesPhenolic compounds

Pharmacological Actions

Anti-inflammatory[15]
Anticancer (preclinical)[4, 5, 9, 15]
Antidiabetic (blood-sugar lowering)[15]
Antimicrobial[8, 11, 12, 15]
Antioxidant[4, 6, 10, 15]
Neuroprotective / cognition support[6, 15]
Anti-inflammatory[1, 2, 3, 4, 12, 15, 18, 20, 26, 27, 29, 32, 33, 34, 35]
Antimicrobial[1, 3, 32, 33, 34]
Antioxidant[1, 2, 5, 9, 12, 17, 32, 33, 34]
Antiviral[2, 29, 30, 31, 32, 33, 34, 36]
Immunomodulator / immune support[4, 5, 9, 10, 15, 23, 26, 29, 32, 33, 34, 35, 36]
Vulnerary (wound healing)[1, 27, 32, 33, 34]
Anticancer (preclinical)[6, 7, 10, 13, 14, 16, 21, 22, 28]
Neuroprotective / cognition support[11, 25]
Hepatoprotective (liver support)[12, 16, 17]
Antidiabetic (blood-sugar lowering)[19, 20, 24]

Traditional & Indicated Uses

Arthritis / joint pain[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Blood sugar / diabetes support[15, 17]Traditional · 1/10

inferred from antidiabetic action

Evidence: 1
Label: Blood sugar / diabetes support
Cancer (anticancer research)[5, 9]Good · 8/10

inferred from anticancer action

Evidence: 8
Label: Cancer (anticancer research)
Cardiovascular / heart health[15, 17]Traditional · 1/10
Evidence: 1
Label: Cardiovascular / heart health
Cognitive function[15, 18]Traditional · 1/10

inferred from neuroprotective action

Evidence: 1
Label: Cognitive function
Infection (general)[15]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Memory[15, 18]Traditional · 1/10

inferred from neuroprotective action

Evidence: 1
Label: Memory
Metabolic support[15, 17]Traditional · 1/10
Evidence: 1
Label: Metabolic support
Skin irritation[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[15]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Arthritis / joint pain[1, 29, 32, 33, 34, 35]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Arthritis / joint pain
Bruising[1, 32, 33, 34]Traditional · 2/10

inferred from vulnerary action

Evidence: 2
Label: Bruising
Cold & flu[29, 30, 31, 32, 33, 34, 36]Traditional · 2/10

inferred from antiviral action

Evidence: 2
Label: Cold & flu
Immune support[10, 15, 29, 32, 33, 34, 35, 36]Traditional · 2/10
Evidence: 2
Label: Immune support
Infection (general)[1, 32, 33, 34]Traditional · 2/10

inferred from antimicrobial action

Evidence: 2
Label: Infection (general)
Inflammation (general)[1, 12, 15, 29, 32, 33, 34, 35]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Inflammation (general)
Skin irritation[1, 29, 32, 33, 34, 35]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Skin irritation
Wounds[1, 27, 32, 33, 34]Traditional · 2/10

inferred from antimicrobial action

Evidence: 2
Label: Wounds
Cancer (anticancer research)[6, 7, 10, 13, 14, 16, 21, 22, 28]Good · 7/10

inferred from anticancer action

Evidence: 7
Label: Cancer (anticancer research)
Blood sugar / diabetes support[19, 20, 24]Traditional · 2/10
Evidence: 2
Label: Blood sugar / diabetes support
Cardiovascular / heart health[18, 19]Traditional · 2/10
Evidence: 2
Label: Cardiovascular / heart health
Cognitive function[25]Traditional · 2/10
Evidence: 2
Label: Cognitive function

Safety, Cautions & Contraindications

Safety note[15, 17, 18]Serious

Generally safe in moderate consumption. High caffeine intake may cause insomnia, anxiety, palpitations, or dependence. Large amounts of green tea extract supplements may be hepatotoxic (rare). May reduce iron absorption if consumed with meals. Avoid very high supplement doses during pregnancy.

Safety note[15, 17, 18, 19]Caution

Duke (2002) rates tea (Camellia sinensis) as ++ and notes anti-aggregant, antioxidant, anticariogenic, and antibacterial activities at the experimental level (score 1). The catechins (EGCG, ECG) and polyphenols are responsible for the antioxidant and anticancer properties under research investigation. Duke notes that green tea preserves more polyphenols than black tea due to less oxidation. Regular tea consumption is associated with reduced cardiovascular risk. Excess consumption (>10 cups daily) may cause fluoride-related bone changes. Caffeine content is relevant for sleep disturbance, anxiety, and interactions with cardiovascular medications (Duke, 2002).

Safety note[32, 33, 34]Caution

Generally very safe and well tolerated. No significant known toxicity or drug interactions. Safe for topical and internal use in normal medicinal doses. Suitable for most adults including children in appropriate doses.

Safety note[32, 33, 34, 37]Info

Duke (2002) rates self-heal as +++ and notes antioxidant (score 2), anti-inflammatory, antiviral, and COX-2 inhibitory activities. The plant contains luteolin, rosmarinic acid, and hyperoside — all with well-documented bioactivities. Hepatoprotective activity has been experimentally demonstrated. Duke notes that self-heal has a broad antimicrobial spectrum and an impressive antioxidant profile, supporting its traditional reputation as a versatile wound-healing herb. No significant safety concerns at normal herbal doses (Duke, 2002).

External Ids

Gbif: 3189635
Wikidata: Q101815
Gbif: 5341297
Wikidata: Q158469

Botanical Description

Evergreen shrub or small tree with glossy, dark green, leathery, finely toothed leaves. Small, fragrant, white flowers with a prominent central boss of yellow stamens are borne singly or in small clusters in the leaf axils. Commercial tea is made from the young leaves and unopened leaf buds ('sprouts'), processed differently to yield green, black, white or oolong tea from the same species.[15]

Height: 1-9 m (kept pruned to 1-1.5 m under cultivation)
Habit: Evergreen shrub or small tree, usually kept pruned as a shrub
Leaves: Glossy, dark green, leathery, finely toothed
Flowers: Small, fragrant, white, with a prominent boss of yellow stamens
Stem: Woody, branching, evergreen
Root: Deep taproot
Fruit: Woody capsule containing a few large seeds
Flowering Period: Autumn to winter

Low, creeping to semi-erect perennial herb (Lamiaceae), 5-30 cm tall, with square, often purplish stems. Leaves are opposite, ovate with slightly toothed margins. Small, two-lipped, violet-purple flowers are densely packed into a compact, club-shaped terminal spike subtended by purplish bracts.[1]

Height: 5-30 cm
Habit: Low, creeping to semi-erect perennial herb
Leaves: Opposite, ovate, slightly toothed
Flowers: Small, two-lipped, violet-purple, in a compact club-shaped terminal spike
Stem: Square, often purplish
Root: Fibrous, spreading perennial rootstock
Fruit: Four small nutlets (typical Lamiaceae schizocarp)
Flowering Period: June-September

Habitat

Native to the subtropical and tropical forests and hillsides of East and South Asia (China, India, Myanmar); cultivated extensively across Asia, Africa and elsewhere on well-drained, acidic upland soils.[15]

Native throughout Europe, Asia and North America (circumboreal), extremely common in lawns, meadows, woodland clearings, roadsides and waste ground, tolerating mowing and a wide range of soils.[1]

Harvesting

The youngest leaves and unopened leaf buds ('flush') are hand- or machine-picked repeatedly through the growing season; how the fresh leaf is subsequently processed (withered, rolled, oxidised, fixed and dried) determines whether it becomes green, black, white or oolong tea.[15]

Parts: Leaf, Young sprouts
Season: Repeated flushes through the growing season

Whole flowering aerial parts (flower, leaf and stem) are cut during flowering (summer) and dried.[1]

Parts: Flower, Leaf, Stem
Season: Summer, during flowering

Traditional Uses

Tea has an ancient East Asian tradition as both a beverage and a medicinal tonic, used for alertness, digestion and general wellbeing; green tea in particular has a long-standing reputation, now widely studied, as an antioxidant, cardiometabolic and cognitive-support beverage.[1, 15]

Selfheal has an extremely broad folk-medicine reputation across European, North American and Traditional Chinese Medicine traditions - as its name suggests, used as an all-purpose wound herb, gargle for sore throat, and internal remedy for fevers and inflammation. Modern research on its triterpenoid, phenolic and polysaccharide constituents supports wide-ranging antioxidant, anti-inflammatory, antimicrobial and antiviral activity.[1]

Preparations

Infusion (green tea)[15]

Young leaf, minimally oxidised, infused in hot water; the least-processed and most-studied form for antioxidant polyphenol content.

Standardised extract[15]

Concentrated leaf extract standardised to catechin (e.g. EGCG) content, taken as capsules; used in some clinical studies, though high-dose extracts carry rare hepatotoxicity concerns.

Infusion (tea)[1]

Dried aerial parts steeped in hot water, taken internally or used as a gargle or wash.

Dosage

Infusion[16]

The EU herbal monograph on green tea leaf (Camelliae sinensis non fermentatum folium) gives, for adults and elderly, 1.8-2.2 g of the whole or comminuted leaf in 100-150 mL of boiling water as an infusion, 3-5 times daily; a powdered herbal substance at 390 mg three times daily (up to 5 if necessary) is also listed. Contraindicated in gastric and duodenal ulcers, cardiovascular disorders such as hypertension and arrhythmia, and hyperthyroidism. Not recommended under 18 years. Educational reference only, not a prescription.

Infusion (tea)[1]

Traditional guidance suggests roughly 2-4 g dried herb per cup as an infusion, up to three times daily, or an equivalent tincture; used topically as a wash or gargle at similar strength. Educational reference only, not a prescription.

References

REF-0755, REF-0756, REF-0757, REF-1960, REF-1961, REF-1962, REF-1963, REF-1964, REF-1965, REF-1966, REF-1967, REF-1968, REF-1969, REF-1970
REF-0659, REF-2422, REF-2423, REF-2424, REF-2425, REF-2878, REF-2879, REF-2880, REF-2881, REF-2882, REF-2883, REF-2884, REF-2885, REF-2886, REF-2887, REF-2888, REF-2911, REF-2912, REF-2913, REF-2914, REF-2915, REF-2916, REF-2917, REF-2918, REF-2919, REF-2920, REF-2921, REF-2922

Drug Class Interactions

Safety note[20, 21]Caution
Drug Class: antihypertensives
Mechanism: Green tea catechins block an intestinal uptake transporter (OATP1A2) that some blood-pressure medicines rely on for absorption. In a controlled study, drinking green tea cut blood levels of the beta-blocker nadolol by about 85% and blunted its blood-pressure-lowering effect. If you take nadolol (or other OATP-transported medicines), separate green tea from the dose by several hours and keep intake consistent; watch that your blood pressure stays controlled.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Not documented

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Mancini, E., Beglinger, C., Drewe, J., Zanchi, D. et al (2017) 'Green tea effects on cognition, mood and human brain function: A systematic review', Phytomedicine, 34, pp. 26-37. doi:10.1016/j.phymed.2017.07.008 Meta-analysis / review
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    https://doi.org/10.2174/1871523015666160915154443
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  15. Chacko, S.M. et al (2010) 'Beneficial effects of green tea: a literature review'. Traditional / reference
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    https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-camellia-sinensis-l-kuntze-non-fermentatum-folium_en.pdf
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.