Plant Comparison

Tea vs Black Cumin

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ATeaCamellia sinensisTheaceaeFull monograph →
Plant BBlack CuminNigella sativaRanunculaceaeFull monograph →

At a glance

Tea and Black Cumin: they share 8 indicated uses (arthritis / joint pain, blood sugar / diabetes support, cancer (anticancer research), …); 5 pharmacological actions in common.

TeaBlack Cumin
Constituents35
Pharmacological actions69
Indicated uses1117
Safety notes22
Cited sources2124
Indicated uses
Only Tea
Cardiovascular / heart healthCognitive functionMemory
Shared (8)
Arthritis / joint painBlood sugar / diabetes supportCancer (anticancer research)Infection (general)Inflammation (general)Metabolic supportSkin irritationWounds
Only Black Cumin
Acid refluxBack painBloatingCold & fluHeadacheImmune supportIndigestionPain (general)Respiratory support
Pharmacological actions
Only Tea
Neuroprotective / cognition support
Shared (5)
Anti-inflammatoryAnticancer (preclinical)Antidiabetic (blood-sugar lowering)AntimicrobialAntioxidant
Only Black Cumin
Analgesic (pain relief)Digestive aidGastroprotectiveImmunomodulator / immune support

Evidence face-off — shared uses

ConditionTeaBlack CuminVerdict
Arthritis / joint pain1/105/10Stronger for Black Cumin
Blood sugar / diabetes support1/105/10Stronger for Black Cumin
Cancer (anticancer research)8/107/10Comparable evidence
Infection (general)1/105/10Stronger for Black Cumin
Inflammation (general)1/105/10Stronger for Black Cumin
Metabolic support1/105/10Stronger for Black Cumin
Skin irritation1/105/10Stronger for Black Cumin
Wounds1/105/10Stronger for Black Cumin

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Catechins (EGCG, ECG) and polyphenols[1, 15]

Principal antioxidant polyphenols, most concentrated in minimally oxidised green tea; epigallocatechin gallate (EGCG) is the best studied.

CatechinsPhenolic compounds
Caffeine and theanine[1]

Caffeine gives tea its mild stimulant effect; L-theanine, a unique amino acid, is associated with calm alertness and modulates caffeine's effects.

Caffeine
Theaflavins and thearubigins[15]

Oxidative polymerisation products of catechins formed during black tea processing, contributing to black tea's colour and its own antioxidant profile.

Thymoquinone[3, 9]

The principal bioactive constituent of the seed oil, responsible for much of its anti-inflammatory, antioxidant and antimicrobial activity.

Volatile oil (nigellone, thymol, carvacrol)[3]

The aromatic fraction of the seed, contributing antimicrobial and antioxidant activity.

Essential (volatile) oilThymolCarvacrol
Fixed oil (linoleic acid, oleic acid)[1]

The bulk lipid fraction of the seed (roughly a third of seed weight by weight), the carrier for the fat-soluble thymoquinone.

Alkaloids (nigellicine, nigellidine)[1]

Minor isoquinoline-type alkaloids studied for antioxidant activity.

Alkaloids
Saponins (alpha-hederin)[1]

Triterpene saponin studied for anticancer and antiparasitic activity.

Saponins

Pharmacological Actions

Anti-inflammatory[15]
Anticancer (preclinical)[4, 5, 9, 15]
Antidiabetic (blood-sugar lowering)[15]
Antimicrobial[8, 11, 12, 15]
Antioxidant[4, 6, 10, 15]
Neuroprotective / cognition support[6, 15]
Analgesic (pain relief)[6, 12, 13, 14, 15, 16, 17, 18]
Anti-inflammatory[1, 2, 4, 8, 9, 10, 12, 13, 14, 15, 16, 17, 18]
Anticancer (preclinical)[7, 12, 13, 14, 15, 16, 17, 18]
Antidiabetic (blood-sugar lowering)[5, 12, 13, 14, 15, 16, 17, 18]
Antimicrobial[3, 11, 12, 13, 14, 15, 16, 17, 18]
Antioxidant[1, 3, 8, 12, 13, 14, 15, 16, 17, 18]
Digestive aid[12, 13, 14, 15, 16, 17, 18]
Gastroprotective[12, 13, 14, 15, 16, 17, 18]
Immunomodulator / immune support[4, 12, 13, 14, 15, 16, 17, 18]

Traditional & Indicated Uses

Arthritis / joint pain[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Blood sugar / diabetes support[15, 17]Traditional · 1/10

inferred from antidiabetic action

Evidence: 1
Label: Blood sugar / diabetes support
Cancer (anticancer research)[5, 9]Good · 8/10

inferred from anticancer action

Evidence: 8
Label: Cancer (anticancer research)
Cardiovascular / heart health[15, 17]Traditional · 1/10
Evidence: 1
Label: Cardiovascular / heart health
Cognitive function[15, 18]Traditional · 1/10

inferred from neuroprotective action

Evidence: 1
Label: Cognitive function
Infection (general)[15]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Infection (general)
Inflammation (general)[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Memory[15, 18]Traditional · 1/10

inferred from neuroprotective action

Evidence: 1
Label: Memory
Metabolic support[15, 17]Traditional · 1/10
Evidence: 1
Label: Metabolic support
Skin irritation[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Wounds[15]Traditional · 1/10

inferred from antimicrobial action

Evidence: 1
Label: Wounds
Acid reflux[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from gastroprotective action

Evidence: 5
Label: Acid reflux
Arthritis / joint pain[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Arthritis / joint pain
Back pain[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from analgesic action

Evidence: 5
Label: Back pain
Bloating[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from digestive action

Evidence: 5
Label: Bloating
Blood sugar / diabetes support[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from antidiabetic action

Evidence: 5
Label: Blood sugar / diabetes support
Cancer (anticancer research)[7]Good · 7/10

inferred from anticancer action

Evidence: 7
Label: Cancer (anticancer research)
Cold & flu[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from immunomodulator action

Evidence: 5
Label: Cold & flu
Headache[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from analgesic action

Evidence: 5
Label: Headache
Immune support[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10
Evidence: 5
Label: Immune support
Indigestion[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from digestive action

Evidence: 5
Label: Indigestion
Infection (general)[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Infection (general)
Inflammation (general)[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Inflammation (general)
Metabolic support[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from antidiabetic action

Evidence: 5
Label: Metabolic support
Pain (general)[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10
Evidence: 5
Label: Pain (general)
Respiratory support[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10
Evidence: 5
Label: Respiratory support
Skin irritation[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Skin irritation
Wounds[12, 13, 14, 15, 16, 17, 18]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Wounds

Safety, Cautions & Contraindications

Safety note[15, 17, 18]Serious

Generally safe in moderate consumption. High caffeine intake may cause insomnia, anxiety, palpitations, or dependence. Large amounts of green tea extract supplements may be hepatotoxic (rare). May reduce iron absorption if consumed with meals. Avoid very high supplement doses during pregnancy.

Safety note[15, 17, 18, 19]Caution

Duke (2002) rates tea (Camellia sinensis) as ++ and notes anti-aggregant, antioxidant, anticariogenic, and antibacterial activities at the experimental level (score 1). The catechins (EGCG, ECG) and polyphenols are responsible for the antioxidant and anticancer properties under research investigation. Duke notes that green tea preserves more polyphenols than black tea due to less oxidation. Regular tea consumption is associated with reduced cardiovascular risk. Excess consumption (>10 cups daily) may cause fluoride-related bone changes. Caffeine content is relevant for sleep disturbance, anxiety, and interactions with cardiovascular medications (Duke, 2002).

Safety note[12, 13, 14, 15, 16, 17, 18]Caution

Generally well-tolerated in clinical trials at doses up to 200 mg/day of oil for 90 days. Potential side effects may include mild gastrointestinal discomfort. Contraindicated during pregnancy due to potential uterine stimulant effects. May interact with immunosuppressants and antidiabetic medications. Allergic reactions possible in sensitive individuals. Consult healthcare provider before use, especially with concurrent medications.

Safety note[12, 13, 14, 15, 16, 17, 18, 19]Caution

Duke (2002) describes black cumin (Nigella sativa) as one of the most multi-active medicinal spices, with experimental evidence for bronchodilation, immunostimulation, hepatoprotection, and antihistaminic activity. The prophet Muhammad reportedly described it as 'a cure for all things except death.' Key bioactive compounds include thymoquinone and nigellone. Antihistaminic and bronchodilatory activity supports its traditional use in asthma and allergic conditions. Duke notes it is generally safe at culinary amounts but recommends caution with medicinal doses in pregnancy due to potential uterotonic effects (Duke, 2002).

External Ids

Gbif: 3189635
Wikidata: Q101815
Gbif: 5371700
Wikidata: Q160575

Botanical Description

Evergreen shrub or small tree with glossy, dark green, leathery, finely toothed leaves. Small, fragrant, white flowers with a prominent central boss of yellow stamens are borne singly or in small clusters in the leaf axils. Commercial tea is made from the young leaves and unopened leaf buds ('sprouts'), processed differently to yield green, black, white or oolong tea from the same species.[15]

Height: 1-9 m (kept pruned to 1-1.5 m under cultivation)
Habit: Evergreen shrub or small tree, usually kept pruned as a shrub
Leaves: Glossy, dark green, leathery, finely toothed
Flowers: Small, fragrant, white, with a prominent boss of yellow stamens
Stem: Woody, branching, evergreen
Root: Deep taproot
Fruit: Woody capsule containing a few large seeds
Flowering Period: Autumn to winter

Annual herb (Ranunculaceae), 20-90 cm tall, with an erect, branched stem and finely divided, pinnately dissected, fern-like leaves. Delicate pale blue-white (occasionally pale purple) flowers, each with 5-10 petal-like sepals, are surrounded by a feathery bract collar. The fruit is an inflated, many-celled capsule that dries and splits to release numerous small, black, angular seeds - the medicinal part.[1]

Height: 20-90 cm
Habit: Erect, branched annual herb
Leaves: Finely pinnately dissected, fern-like
Flowers: Pale blue-white (occasionally pale purple), 5-10 petal-like sepals, feathery bract collar
Stem: Erect, branched
Root: Slender taproot
Fruit: Inflated capsule splitting to release small black angular seeds
Flowering Period: June-August

Habitat

Native to the subtropical and tropical forests and hillsides of East and South Asia (China, India, Myanmar); cultivated extensively across Asia, Africa and elsewhere on well-drained, acidic upland soils.[15]

Native to the Mediterranean basin, southern Europe, western Asia and North Africa, and widely cultivated as a spice and medicinal crop across the Middle East, South Asia and North Africa; grows in cultivated fields and on disturbed ground.[1]

Harvesting

The youngest leaves and unopened leaf buds ('flush') are hand- or machine-picked repeatedly through the growing season; how the fresh leaf is subsequently processed (withered, rolled, oxidised, fixed and dried) determines whether it becomes green, black, white or oolong tea.[15]

Parts: Leaf, Young sprouts
Season: Repeated flushes through the growing season

Seed capsules are harvested once dried and brown (late summer), then threshed to release the small black seeds. Seed is stored whole and either used directly or cold-pressed for oil shortly before use to preserve the volatile thymoquinone-rich fraction.[1]

Parts: Seed
Season: Late summer, once capsules have dried

Traditional Uses

Tea has an ancient East Asian tradition as both a beverage and a medicinal tonic, used for alertness, digestion and general wellbeing; green tea in particular has a long-standing reputation, now widely studied, as an antioxidant, cardiometabolic and cognitive-support beverage.[1, 15]

One of the most celebrated medicinal seeds in Middle Eastern and Islamic traditional medicine - known as 'Habbatul Barakah' (the blessed seed) - black seed has traditionally been used for digestive complaints, respiratory conditions (asthma, cough), pain, inflammation, skin conditions and as a general tonic. Modern research on its principal constituent thymoquinone supports broad anti-inflammatory, antioxidant, antimicrobial, antidiabetic and immunomodulatory activity.[1, 2, 9]

Preparations

Infusion (green tea)[15]

Young leaf, minimally oxidised, infused in hot water; the least-processed and most-studied form for antioxidant polyphenol content.

Standardised extract[15]

Concentrated leaf extract standardised to catechin (e.g. EGCG) content, taken as capsules; used in some clinical studies, though high-dose extracts carry rare hepatotoxicity concerns.

Whole or ground seed[1]

Seed eaten directly, sprinkled on food, or ground into a paste - the traditional culinary-medicinal form.

Cold-pressed seed oil[3, 9]

The form most used in clinical trials, taken orally in capsules or as a liquid.

Dosage

Infusion[16]

The EU herbal monograph on green tea leaf (Camelliae sinensis non fermentatum folium) gives, for adults and elderly, 1.8-2.2 g of the whole or comminuted leaf in 100-150 mL of boiling water as an infusion, 3-5 times daily; a powdered herbal substance at 390 mg three times daily (up to 5 if necessary) is also listed. Contraindicated in gastric and duodenal ulcers, cardiovascular disorders such as hypertension and arrhythmia, and hyperthyroidism. Not recommended under 18 years. Educational reference only, not a prescription.

Seed oil[12, 13, 14, 15, 16, 17, 18]

Clinical trials have generally been well tolerated at doses up to about 200 mg/day of oil taken for up to 90 days. Educational reference only, not a prescription; avoid medicinal doses in pregnancy.

References

REF-0755, REF-0756, REF-0757, REF-1960, REF-1961, REF-1962, REF-1963, REF-1964, REF-1965, REF-1966, REF-1967, REF-1968, REF-1969, REF-1970
REF-2065, REF-2066, REF-2067, REF-2068, REF-2069, REF-2070, REF-2071, REF-2072, REF-2073, REF-2074, REF-2075

Drug Class Interactions

Safety note[20, 21]Caution
Drug Class: antihypertensives
Mechanism: Green tea catechins block an intestinal uptake transporter (OATP1A2) that some blood-pressure medicines rely on for absorption. In a controlled study, drinking green tea cut blood levels of the beta-blocker nadolol by about 85% and blunted its blood-pressure-lowering effect. If you take nadolol (or other OATP-transported medicines), separate green tea from the dose by several hours and keep intake consistent; watch that your blood pressure stays controlled.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Safety note[20, 21, 22]Caution
Drug Class: antidiabetics
Mechanism: Black seed (Nigella sativa) lowers fasting blood glucose and HbA1c in trials in people with prediabetes and type 2 diabetes (confirmed by meta-analysis); combined with diabetes medicines it may add to blood-sugar lowering, so monitor blood sugar.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03
Safety note[23, 24]Caution
Drug Class: antihypertensives
Mechanism: Black seed (Nigella sativa) modestly lowers blood pressure - two meta-analyses of randomised trials found reductions of roughly 3 mmHg systolic and 3 mmHg diastolic. Combined with blood-pressure medicines it may add to their effect, so monitor your blood pressure.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-03

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

  1. Mancini, E., Beglinger, C., Drewe, J., Zanchi, D. et al (2017) 'Green tea effects on cognition, mood and human brain function: A systematic review', Phytomedicine, 34, pp. 26-37. doi:10.1016/j.phymed.2017.07.008 Meta-analysis / review
    https://doi.org/10.1016/j.phymed.2017.07.008
  2. Musial, C., Kuban-Jankowska, A. and Gorska-Ponikowska, M (2020) 'Beneficial Properties of Green Tea Catechins', International Journal of Molecular Sciences, 21(5), pp. 1744. doi:10.3390/ijms21051744 Traditional / reference
    https://doi.org/10.3390/ijms21051744
  3. Ohishi, T., Goto, S., Monira, P., Isemura, M. and Nakamura, Y (2016) 'Anti-inflammatory Action of Green Tea', Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry, 15(2), pp. 74-90. doi:10.2174/1871523015666160915154443 Traditional / reference
    https://doi.org/10.2174/1871523015666160915154443
  4. Zhao, T., Li, C., Wang, S. and Song, X (2022) 'Green Tea (Camellia sinensis): A Review of Its Phytochemistry, Pharmacology, and Toxicology', Molecules, 27(12), pp. 3909. doi:10.3390/molecules27123909 Meta-analysis / review
    https://doi.org/10.3390/molecules27123909
  5. Filippini, T., Malavolti, M., Borrelli, F., Izzo, A.A., Fairweather-Tait, S.J., Horneber, M. and Vinceti, M (2020) 'Green tea (Camellia sinensis) for the prevention of cancer', Cochrane Database of Systematic Reviews, 3(3), pp. CD005004. doi:10.1002/14651858.CD005004.pub3 Meta-analysis / review
    https://doi.org/10.1002/14651858.CD005004.pub3
  6. Prasanth, M.I., Sivamaruthi, B.S., Chaiyasut, C. and Tencomnao, T (2019) 'A Review of the Role of Green Tea (Camellia sinensis) in Antiphotoaging, Stress Resistance, Neuroprotection, and Autophagy', Nutrients, 11(2), pp. 474. doi:10.3390/nu11020474 Meta-analysis / review
    https://doi.org/10.3390/nu11020474
  7. Bedrood, Z., Rameshrad, M. and Hosseinzadeh, H (2018) 'Toxicological effects of Camellia sinensis (green tea): A review', Phytotherapy Research, 32(7), pp. 1163-1180. doi:10.1002/ptr.6063 Meta-analysis / review
    https://doi.org/10.1002/ptr.6063
  8. Hamilton-Miller, J.M.T (2001) 'Anti-cariogenic properties of tea (Camellia sinensis)', Journal of Medical Microbiology, 50(4), pp. 299-302. doi:10.1099/0022-1317-50-4-299 Meta-analysis / review
    https://doi.org/10.1099/0022-1317-50-4-299
  9. Conde, V.R., Alves, M.G., Oliveira, P.F. and Silva, B.M (2015) 'Tea (Camellia sinensis (L.)): a putative anticancer agent in bladder carcinoma?', Anti-Cancer Agents in Medicinal Chemistry, 15(1), pp. 26-36. doi:10.2174/1566524014666141203143143 Meta-analysis / review
    https://doi.org/10.2174/1566524014666141203143143
  10. Moore, R.J., Jackson, K.G. and Minihane, A.M (2009) 'Green tea (Camellia sinensis) catechins and vascular function', British Journal of Nutrition, 102(12), pp. 1790-1802. doi:10.1017/S0007114509991218 Meta-analysis / review
    https://doi.org/10.1017/S0007114509991218
  11. Gaur, R. and Bao, G.H (2021) 'Chemistry and Pharmacology of Natural Catechins from Camellia sinensis as Anti-MRSA Agents', Current Topics in Medicinal Chemistry, 21(17), pp. 1519-1537. doi:10.2174/1568026621666210524100632 Meta-analysis / review
    https://doi.org/10.2174/1568026621666210524100632
  12. Tafazoli, A. and Tafazoli Moghadam, E (2020) 'Camellia Sinensis Mouthwashes in Oral Care: a Systematic Review', Journal of Dentistry (Shiraz), 21(4), pp. 249-262. doi:10.30476/DENTJODS.2020.83204.1045 Meta-analysis / review
    https://doi.org/10.30476/DENTJODS.2020.83204.1045
  13. Albassam, A.A. and Markowitz, J.S (2017) 'An Appraisal of Drug-Drug Interactions with Green Tea (Camellia sinensis)', Planta Medica, 83(6), pp. 496-508. doi:10.1055/s-0043-100934 Meta-analysis / review
    https://doi.org/10.1055/s-0043-100934
  14. Gramza-Michalowska, A (2014) 'Caffeine in tea Camellia sinensis - content, absorption, benefits and risks of consumption', Journal of Nutrition, Health & Aging, 18(2), pp. 143-149. doi:10.1007/s12603-013-0404-1 Meta-analysis / review
    https://doi.org/10.1007/s12603-013-0404-1
  15. Chacko, S.M. et al (2010) 'Beneficial effects of green tea: a literature review'. Traditional / reference
    https://scholar.google.com/scholar?q=Beneficial%20effects%20of%20green%20tea%3A%20a%20literature%20review
  16. European Medicines Agency (HMPC) (2013) 'Community herbal monograph on Camellia sinensis (L.) Kuntze, non fermentatum folium'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-camellia-sinensis-l-kuntze-non-fermentatum-folium_en.pdf Traditional / reference
    https://www.ema.europa.eu/en/documents/herbal-monograph/final-community-herbal-monograph-camellia-sinensis-l-kuntze-non-fermentatum-folium_en.pdf
  17. Drake, V.J (2015) 'Tea catechins and cardiovascular disease risk', 74(1), pp. 39--46. Traditional / reference
    https://scholar.google.com/scholar?q=Tea%20catechins%20and%20cardiovascular%20disease%20risk
  18. Nobre, A.C., Rao, A. and Owen, G.N (2008) 'L-theanine, a natural constituent in tea, and its effect on mental state', pp. 167--168. Traditional / reference
    https://scholar.google.com/scholar?q=L-theanine%2C%20a%20natural%20constituent%20in%20tea%2C%20and%20its%20effect%20on%20mental%20state
  19. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  20. Misaka, S., Yatabe, J., Muller, F., Takano, K., Kawabe, K., Glaeser, H., Yatabe, M.S., Onoue, S., Werba, J.P., Watanabe, H., Yamada, S., Fromm, M.F. and Kimura, J (2014) 'Green tea ingestion greatly reduces plasma concentrations of nadolol in healthy subjects', Clinical Pharmacology and Therapeutics, 95(4), pp. 432-438. doi:10.1038/clpt.2013.241 Randomized trial
    https://doi.org/10.1038/clpt.2013.241
  21. Werba, J.P., Misaka, S., Giroli, M.G., Shimomura, K., Amato, M., Simonelli, N., Vigo, L. and Tremoli, E (2018) 'Update of green tea interactions with cardiovascular drugs and putative mechanisms', Journal of Food and Drug Analysis, 26(2S), pp. S72-S77. doi:10.1016/j.jfda.2018.01.008 Meta-analysis / review
    https://doi.org/10.1016/j.jfda.2018.01.008
  1. Hannan, M.A., Rahman, M.A., Sohag, A.A.M., Uddin, M.J., Dash, R., Sikder, M.H., Rahman, M.S., Timalsina, B., Munni, Y.A. and Sarker, P.P (2021) 'Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety', Nutrients, 13(6), pp. 1784. doi:10.3390/nu13061784 Meta-analysis / review
    https://doi.org/10.3390/nu13061784
  2. Ahmad, A., Husain, A., Mujeeb, M., Khan, S.A., Najmi, A.K., Siddique, N.A., Damanhouri, Z.A. and Anwar, F (2013) 'A review on therapeutic potential of Nigella sativa: A miracle herb', Asian Pacific Journal of Tropical Biomedicine, 3(5), pp. 337-352. doi:10.1016/S2221-1691(13)60075-1 Meta-analysis / review
    https://doi.org/10.1016/S2221-1691(13)60075-1
  3. Chatterjee, G., Saha, A.K., Khurshid, S. and Saha, A (2025) 'A Comprehensive Review of the Antioxidant, Antimicrobial, and Therapeutic Efficacies of Black Cumin (Nigella sativa L.) Seed Oil and Its Thymoquinone', Journal of Medicinal Food, 28(4), pp. 325-339. doi:10.1089/jmf.2024.k.0149 Meta-analysis / review
    https://doi.org/10.1089/jmf.2024.k.0149
  4. Majdalawieh, A.F. and Fayyad, M.W (2015) 'Immunomodulatory and anti-inflammatory action of Nigella sativa and thymoquinone: A comprehensive review', International Immunopharmacology, 28(1), pp. 295-304. doi:10.1016/j.intimp.2015.06.023 Meta-analysis / review
    https://doi.org/10.1016/j.intimp.2015.06.023
  5. Shaukat, A., Zaidi, A., Anwar, H. and Kizilbash, N (2023) 'Mechanism of the antidiabetic action of Nigella sativa and Thymoquinone: a review', Frontiers in Nutrition, 10, pp. 1126272. doi:10.3389/fnut.2023.1126272 Meta-analysis / review
    https://doi.org/10.3389/fnut.2023.1126272
  6. Beheshti, F., Khazaei, M. and Hosseini, M (2016) 'Neuropharmacological effects of Nigella sativa', Avicenna Journal of Phytomedicine, 6(1), pp. 104-116. Meta-analysis / review
    https://scholar.google.com/scholar?q=Neuropharmacological%20effects%20of%20Nigella%20sativa
  7. Shafiq, H., Ahmad, A., Masud, T. and Kaleem, M (2014) 'Cardio-protective and anti-cancer therapeutic potential of Nigella sativa', Iranian Journal of Basic Medical Sciences, 17(12), pp. 967-979. Meta-analysis / review
    https://scholar.google.com/scholar?q=Cardio-protective%20and%20anti-cancer%20therapeutic%20potential%20of%20Nigella%20sativa
  8. Bordoni, L., Fedeli, D., Nasuti, C., Maggi, F., Papa, F., Wabitsch, M., De Caterina, R. and Gabbianelli, R (2019) 'Antioxidant and Anti-Inflammatory Properties of Nigella sativa Oil in Human Pre-Adipocytes', Antioxidants, 8(2), pp. 51. doi:10.3390/antiox8020051 Preclinical
    https://doi.org/10.3390/antiox8020051
  9. Gholamnezhad, Z., Havakhah, S. and Boskabady, M.H (2016) 'Preclinical and clinical effects of Nigella sativa and its constituent, thymoquinone: A review', Journal of Ethnopharmacology, 190, pp. 372-386. doi:10.1016/j.jep.2016.06.061 Meta-analysis / review
    https://doi.org/10.1016/j.jep.2016.06.061
  10. Ali, B.H. and Blunden, G (2003) 'Pharmacological and toxicological properties of Nigella sativa', Phytotherapy Research, 17(4), pp. 299-305. doi:10.1002/ptr.1309 Meta-analysis / review
    https://doi.org/10.1002/ptr.1309
  11. Al-Attass, S.A., Zahran, F.M. and Turkistany, S.A (2016) 'Nigella sativa and its active constituent thymoquinone in oral health', Saudi Medical Journal, 37(3), pp. 235-244. doi:10.15537/smj.2016.3.13006 Meta-analysis / review
    https://doi.org/10.15537/smj.2016.3.13006
  12. Ahmad A, Husain A, Mujeeb M, et al. A review on therapeutic potential of Nigella sativa: A miracle herb. Asian Pac J Trop Biomed. 2013;3 (2013) ';3(5):337-352', 3(5). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC3642442/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC3642442/
  13. Darakhshan S, Bidmeshki Pour A, Hosseinzadeh Colagar A, Sisakhtnezhad S. Thymoquinone and its therapeutic potentials. Pharmacol Res. 2015;95-96:138-158. https://pmc.ncbi.nlm.nih.gov/articles/PMC4387230/ (2015) ';95-96:138-158'. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC4387230/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC4387230/
  14. Forouzanfar F, Bazzaz BSF, Hosseinzadeh H. A review of ethnobotany, phytochemistry, antimicrobial pharmacology and toxicology of Nigella sativa L. Biomed Pharmacother. 2021;142:112040. https://www.sciencedirect.com/science/article/pii/S0753332221009665 (2021) ';142:112040'. Available at: https://www.sciencedirect.com/science/article/pii/S0753332221009665 Traditional / reference
    https://www.sciencedirect.com/science/article/pii/S0753332221009665
  15. Gholamnezhad Z, Keyhanmanesh R, Boskabady MH. Anti-inflammatory, antioxidant, and immunomodulatory aspects of Nigella sativa for its preventive and bronchodilatory effects on obstructive respiratory diseases. Biomed Pharmacother. 2021;136:111240. https://www.sciencedirect.com/science/article/pii/S0753332221002778 (2021) ';136:111240'. Available at: https://www.sciencedirect.com/science/article/pii/S0753332221002778 Traditional / reference
    https://www.sciencedirect.com/science/article/pii/S0753332221002778
  16. Hannan MA, Rahman MA, Sohag AAM, et al. Black cumin (2021) ';13(6):1784', 13(6). doi:10.3389/fphar.2021.625386/full Randomized trial
    https://doi.org/10.3389/fphar.2021.625386/full
  17. Kooti W, Hasanzadeh-Noohi Z, Sharafi-Ahvazi N, et al. Phytochemistry, pharmacology, and therapeutic uses of black seed (2016) ';22(3):231-237', 22(3). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC8225153/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC8225153/
  18. Tavakkoli A, Mahdian V, Razavi BM, Hosseinzadeh H. Review on clinical trials of black seed (2017) ';20(3):179-193', 20(3). Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5633670/ Traditional / reference
    https://pmc.ncbi.nlm.nih.gov/articles/PMC5633670/
  19. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  20. Saadati, S., Naseri, K., Asbaghi, O., Abhari, K., Zhang, P., Li, H.B. and Gan, R.Y (2022) 'Nigella sativa supplementation improves cardiometabolic indicators in population with prediabetes and type 2 diabetes mellitus: A systematic review and meta-analysis of randomized controlled trials', Frontiers in Nutrition, 9, pp. 977756. doi:10.3389/fnut.2022.977756 Meta-analysis / review
    https://doi.org/10.3389/fnut.2022.977756
  21. Willcox, M.L., Elugbaju, C., Al-Anbaki, M., Lown, M. and Graz, B (2021) 'Effectiveness of Medicinal Plants for Glycaemic Control in Type 2 Diabetes: An Overview of Meta-Analyses of Clinical Trials', Frontiers in Pharmacology, 12, pp. 777561. doi:10.3389/fphar.2021.777561 Meta-analysis / review
    https://doi.org/10.3389/fphar.2021.777561
  22. Daryabeygi-Khotbehsara, R., Golzarand, M., Ghaffari, M.P. and Djafarian, K (2017) 'Nigella sativa improves glucose homeostasis and serum lipids in type 2 diabetes: a systematic review and meta-analysis', Complementary Therapies in Medicine, 35, pp. 6-13. doi:10.1016/j.ctim.2017.08.016 Meta-analysis / review
    https://doi.org/10.1016/j.ctim.2017.08.016
  23. Sahebkar, A., Soranna, D., Liu, X., Thomopoulos, C., Simental-Mendia, L.E., Derosa, G., Maffioli, P. and Parati, G (2016) 'A systematic review and meta-analysis of randomized controlled trials investigating the effects of supplementation with Nigella sativa (black seed) on blood pressure', Journal of Hypertension, 34(11), pp. 2127-2135. doi:10.1097/HJH.0000000000001049 Meta-analysis / review
    https://doi.org/10.1097/HJH.0000000000001049
  24. Kavyani, Z., Musazadeh, V., Safaei, E., Mohammadi Asmaroud, M., Khashakichafi, F., Ahrabi, S.S. and Dehghan, P (2023) 'Antihypertensive effects of Nigella sativa supplementation: an updated systematic review and meta-analysis of randomized controlled trials', Phytotherapy Research, 37(8), pp. 3224-3238. doi:10.1002/ptr.7891 Meta-analysis / review
    https://doi.org/10.1002/ptr.7891

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.