Plant Comparison
Pot marigold vs Dandelion
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Pot marigold and Dandelion: both belong to the Asteraceae family; they share 6 indicated uses (arthritis / joint pain, cancer (anticancer research), infection (general), …); 4 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Pot marigold | Dandelion | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 5/10 | 1/10 | Stronger for Pot marigold |
| Cancer (anticancer research) | 7/10 | 2/10 | Stronger for Pot marigold |
| Infection (general) | 5/10 | 1/10 | Stronger for Pot marigold |
| Inflammation (general) | 5/10 | 1/10 | Stronger for Pot marigold |
| Skin irritation | 5/10 | 1/10 | Stronger for Pot marigold |
| Wounds | 5/10 | 1/10 | Stronger for Pot marigold |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
Principal wound-healing and anti-inflammatory constituents of the flower.
Antioxidant flavonoids and carotenoids give the flower its orange-yellow colour and contribute to its antioxidant activity.
Minor aromatic and resinous constituents of the flower head.
Bitter principles (e.g. taraxacin) responsible for the characteristic bitterness and bitter-tonic action.
Including taraxasterol; contribute to anti-inflammatory and hepatoprotective signals.
Antioxidant constituents (e.g. chicoric acid, luteolin derivatives).
Pharmacological Actions
Traditional & Indicated Uses
inferred from anti-inflammatory action
A Calendula officinalis (LACE) aqueous extract inhibits proliferation (70-100%) of leukemia, melanoma, breast, prostate, lung and colon cancer cell lines via G0/G1 arrest and caspase-3 apoptosis and inhibits melanoma growth in nude mice; a systematic review documents its cytotoxic and antimetastatic antitumour activity (preclinical).
inferred from antifungal action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from bitter-tonic action
inferred from anti-inflammatory action
inferred from anticancer action
inferred from hepatoprotective action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from choleretic action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from diuretic action
Dandelion root and leaf lowered serum lipids and oxidative stress (preclinical).
Safety, Cautions & Contraindications
Generally very safe for topical use. May cause contact dermatitis in rare cases (Asteraceae family allergy). Internal use is safe in normal doses. Avoid during pregnancy at therapeutic doses (uterine stimulant potential). Generally safe during breastfeeding for topical use.
Duke (2002) rates calendula (Calendula officinalis) and notes anti-inflammatory, wound-healing (vulnerary), antifungal, and antispasmodic activities at experimental levels. Commission E (KOM) approves calendula flower for wound healing and anti-inflammatory uses, both topically and as a gargle. The plant contains flavonoids, triterpene saponins (oleanolic acid glycosides), and essential oils. Dose: 1–2 g dried flower as tea (for mouth rinse/gargle); or as cream/ointment containing 2–5% calendula extract for topical use. Duke notes that calendula is generally very well-tolerated, though Asteraceae sensitivity can occasionally cause allergic reactions (Duke, 2002).
Allergy risk in individuals sensitive to Asteraceae (daisy family) plants such as ragweed and chamomile.
Avoid medicinal use in anyone with a blocked bile duct or gallstones; use caution with gallbladder or serious liver disease.
May potentiate prescription diuretics; possible interactions with lithium and drugs metabolised by the liver.
Can accumulate soil pollutants and heavy metals; harvest from clean, unpolluted sites.
Use during pregnancy or breastfeeding should be guided by a qualified practitioner. Herbal use should support, not replace, conventional medical care.
External Ids
Botanical Description
Aromatic annual or short-lived perennial herb with soft, hairy, oblong leaves and branching, slightly sticky stems. The flower heads are bright orange to yellow, daisy-like, with numerous narrow ray florets surrounding a darker central disc, opening in sunlight and closing at dusk.[1]
Perennial herb (Asteraceae) with a deep taproot, forming a basal rosette of deeply toothed, lance-shaped leaves - the name 'dandelion' comes from the French 'dent-de-lion', lion's tooth. Hollow flowering stalks each bear a single, bright yellow composite flower head made entirely of ray florets, followed by the familiar spherical 'clock' of parachute-tufted seeds (achenes) that disperse on the wind.[50]
Habitat
Widely cultivated as a garden and medicinal plant; believed native to southern Europe and the Mediterranean, now naturalised in gardens and waste ground worldwide.[1]
Native to Europe and Asia, now a cosmopolitan weed found on every continent except Antarctica; grows in lawns, meadows, roadsides, waste ground and disturbed soil of almost any type.[50]
Harvesting
The flower heads (or just the ray-floret petals) are picked by hand as they open, through the flowering season, and dried quickly in a warm, shaded, airy place to preserve colour and resin content.[1]
Leaves are picked young in spring for the mildest flavour; the root is dug in autumn (traditionally after the first frost), when its inulin and bitter-principle content is considered optimal; flowers are picked as they open.[50, 53]
Traditional Uses
Calendula flower is one of the most widely used topical wound-healing and skin-soothing herbs in Western herbal medicine, applied to cuts, grazes, minor burns and skin inflammation, and used internally as a gentle anti-inflammatory and antimicrobial remedy and as a gargle for mouth and throat irritation.[1]
Dandelion is one of the most widely used bitter tonic herbs worldwide, traditionally taken as a digestive bitter and mild diuretic - the French name 'pissenlit' (wet-the-bed) reflects this - and the root specifically as a liver and gallbladder tonic. Every part is also used as food: spring greens, roasted-root coffee substitute, and flower wine.[50]
Preparations
Dried petals infused in a carrier oil, used as a soothing base for topical creams and balms for skin healing.
Standardised flower extract formulated into a cream or ointment for topical wound and skin care; the best-studied modern form.
Dried flower infused in hot water, 1-2 g in 150 ml, used still warm as a mouth rinse or gargle 2-4 times daily. The EU herbal monograph's posology for this preparation is OROMUCOSAL only - it does not support taking the infusion internally. Educational reference only, not a prescription.
Dosage
The EU herbal monograph gives semi-solid preparations containing the equivalent of 2-10% herbal substance, applied as a thin layer to the affected area 2 to 4 times daily. Educational reference only, not a prescription.
The EU herbal monograph gives 1-2 g of the flower in 150 mL water as an infusion, used still warm for rinsing and gargling 2 to 4 times daily, or to prepare impregnated dressings for the skin. This is an oromucosal and cutaneous preparation, not an oral tea. Educational reference only, not a prescription.
Traditional guidance suggests roughly 4-10 g dried leaf, or 2-8 g dried root, per day as an infusion or decoction, divided into 2-3 doses. Educational reference only, not a prescription; avoid in bile-duct obstruction or gallstones, and harvest away from polluted ground.
References
Lookalikes Review
References & Sources
- Givol, O., Kornhaber, R., Visentin, D., Cleary, M. et al (2019) 'A systematic review of Calendula officinalis extract for wound healing', Wound Repair and Regeneration, 27(5), pp. 548-561. doi:10.1111/wrr.12737 Meta-analysis / review
https://doi.org/10.1111/wrr.12737 - Shahane, K., Kshirsagar, M., Tambe, S., Jain, D. et al (2023) 'An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L', Pharmaceuticals (Basel), 16(4), pp. 611. doi:10.3390/ph16040611 Traditional / reference
https://doi.org/10.3390/ph16040611 - Saffari, E., Mohammad-Alizadeh-Charandabi, S., Adibpour, M., Mirghafourvand, M. et al (2016) 'Comparing the effects of Calendula officinalis and clotrimazole on vaginal Candidiasis: A randomized controlled trial', Women & Health, 57(10), pp. 1145-1160. doi:10.1080/03630242.2016.1263272 Randomized trial
https://doi.org/10.1080/03630242.2016.1263272 - Cruceriu, D., Balacescu, O. and Rakosy, E (2018) 'Calendula officinalis: potential roles in cancer treatment and palliative care', Integrative Cancer Therapies, 17(4), pp. 1068-1078. doi:10.1177/1534735418803766 Meta-analysis / review
https://doi.org/10.1177/1534735418803766 - Rezai, S., Rahzani, K., Hekmatpou, D. and Rostami, A (2023) 'Effect of oral Calendula officinalis on second-degree burn wound healing', Scars, Burns & Healing, 9, pp. 20595131221134053. doi:10.1177/20595131221134053 Randomized trial
https://doi.org/10.1177/20595131221134053 - Kadowaki, W., Miyata, R., Mizuno, S., Fujinami, M., Sato, Y. and Kumazawa, S (2023) 'Prenylated acetophenones from the roots of Calendula officinalis and their anti-inflammatory activity', Bioscience, Biotechnology, and Biochemistry, 87(7), pp. 683-687. doi:10.1093/bbb/zbad042 Preclinical
https://doi.org/10.1093/bbb/zbad042 - Samra, R.M., Maatooq, G.T. and Zaki, A.A (2022) 'A new antiprotozoal compound from Calendula officinalis', Natural Product Research, 36(22), pp. 5747-5752. doi:10.1080/14786419.2021.2023868 Preclinical
https://doi.org/10.1080/14786419.2021.2023868 - Kaur, J., Sidhu, S., Chopra, K. and Khan, M.U (2016) 'Calendula officinalis ameliorates l-arginine-induced acute necrotizing pancreatitis in rats', Pharmaceutical Biology, 54(12), pp. 2951-2959. doi:10.1080/13880209.2016.1195848 Preclinical
https://doi.org/10.1080/13880209.2016.1195848 - Aro, A.A., Perez, M.O., Vieira, C.P., Esquisatto, M.A.M., Rodrigues, R.A.F., Gomes, L. and Pimentel, E.R (2014) 'Effect of Calendula officinalis cream on achilles tendon healing', Anatomical Record, 298(2), pp. 428-435. doi:10.1002/ar.23057 Preclinical
https://doi.org/10.1002/ar.23057 - Zhang, X., Wang, R., Finiuk, N., Stoika, R., Lin, H., Wang, X. and Jin, M (2023) 'Active compounds from Calendula officinalis flowers act via PI3K and ERK signaling pathways to offer neuroprotective effects against Parkinson's disease', Food Science & Nutrition, 12(1), pp. 450-458. doi:10.1002/fsn3.3792 Preclinical
https://doi.org/10.1002/fsn3.3792 - Kadowaki, W., Miyata, R., Fujinami, M., Sato, Y. and Kumazawa, S (2023) 'Catechol-O-methyltransferase inhibitors from Calendula officinalis leaf', Molecules, 28(3), pp. 1333. doi:10.3390/molecules28031333 Preclinical
https://doi.org/10.3390/molecules28031333 - European Medicines Agency (HMPC) (2018) 'European Union herbal monograph on Calendula officinalis L., flos, Revision 1'. Available at: https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-calendula-officinalis-l-flos-revision-1_en.pdf Traditional / reference
https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-calendula-officinalis-l-flos-revision-1_en.pdf - Hoffmann, D (2003) 'Medical Herbalism'. Traditional / reference
https://scholar.google.com/scholar?q=Medical%20Herbalism - Nicolaus, C. et al (2017) 'A double-blind, randomized controlled trial to investigate the efficacy and safety of a monograph-based Calendula cream versus a comparator cream', 35(1), pp. 81--89. Randomized trial
https://scholar.google.com/scholar?q=A%20double-blind%2C%20randomized%20controlled%20trial%20to%20investigate%20the%20efficacy%20and%20safety%20of%20a%20monograph-based%20Calendula%20cream%20versus%20a%20comparator%20cream - Preethi, K.C. and Kuttan, R (2009) 'Wound healing activity of flower extract of Calendula officinalis', 20(1), pp. 73--79. doi:10.1515/jbcpp.2009.20.1.73 Preclinical
https://doi.org/10.1515/jbcpp.2009.20.1.73 - Jimenez-Medina, E. and Garcia-Lora, A. and Paco, L. and Algarra, I. and Collado, A. and Garrido, F (2006) 'A new extract of the plant Calendula officinalis produces a dual in vitro effect: cytotoxic anti-tumor activity and lymphocyte activation', BMC Cancer, 6, pp. 119. doi:10.1186/1471-2407-6-119 Preclinical
https://doi.org/10.1186/1471-2407-6-119 - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
- Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Botanical Society of Britain and Ireland (n.d.) 'Dandelion identification (Taraxacum)'. Available at: https://bsbi.org/identification/taraxacum Traditional / reference
https://bsbi.org/identification/taraxacum - Farm and Dairy (2021) 'How to harvest and use dandelion roots, leaves and flowers'. Available at: https://www.farmanddairy.com/news/top-stories/how-to-harvest-and-use-dandelion-roots-leaves-and-flowers/656605.html Traditional / reference
https://www.farmanddairy.com/news/top-stories/how-to-harvest-and-use-dandelion-roots-leaves-and-flowers/656605.html - First Nature (n.d.) 'Taraxacum officinale, Dandelion: identification, distribution, habitat'. Available at: https://www.first-nature.com/flowers/taraxacum-officinale.php Traditional / reference
https://www.first-nature.com/flowers/taraxacum-officinale.php - Flora of the Southeastern United States (n.d.) 'Taraxacum officinale (Common Dandelion)'. Available at: https://fsus.ncbg.unc.edu/main.php?pg=show-taxon.php&plantname=taraxacum+officinale Traditional / reference
https://fsus.ncbg.unc.edu/main.php?pg=show-taxon.php&plantname=taraxacum+officinale - Good Grub (n.d.) 'Plant of the Month: Dandelion!'. Available at: https://www.goodgrub.org/post/plant-of-the-month-dandelion Traditional / reference
https://www.goodgrub.org/post/plant-of-the-month-dandelion - HerbaWave (2026) 'Dandelion (Taraxacum officinale) – Origin, Phytochemistry, Traditional Use'. Available at: https://herbawave.com/en/learn/ingredients/dandelion Traditional / reference
https://herbawave.com/en/learn/ingredients/dandelion - Mossy Oak (2025) 'How to Forage for Dandelions'. Available at: https://www.mossyoak.com/our-obsession/blogs/recipes/how-to-forage-for-dandelions Traditional / reference
https://www.mossyoak.com/our-obsession/blogs/recipes/how-to-forage-for-dandelions - Practical Frugality (2024) 'Dandelion: Foraging Guide, Recipes & Harvesting Tips'. Available at: https://www.practicalfrugality.com/dandelion/ Traditional / reference
https://www.practicalfrugality.com/dandelion/ - Under A Tin Roof (2025) 'The Ultimate Guide to Foraging Dandelions'. Available at: https://underatinroof.com/blog/the-ultimate-guide-to-foraging-dandelions-how-to-harvest-flowers-greens-and-roots Traditional / reference
https://underatinroof.com/blog/the-ultimate-guide-to-foraging-dandelions-how-to-harvest-flowers-greens-and-roots - University of Massachusetts (n.d.) 'Taraxacum officinale'. Available at: https://extension.umass.edu/weed-herbarium/weeds/taraxacum-officinale/ Traditional / reference
https://extension.umass.edu/weed-herbarium/weeds/taraxacum-officinale/ - Wikipedia (n.d.) 'Taraxacum officinale'. Available at: https://en.wikipedia.org/wiki/Taraxacum_officinale Traditional / reference
https://en.wikipedia.org/wiki/Taraxacum_officinale - University of Wisconsin-Madison Division of Extension (n.d.) 'Dandelion, Taraxacum officinale'. Available at: https://hort.extension.wisc.edu/articles/dandelion-taraxacum-officinale/ Traditional / reference
https://hort.extension.wisc.edu/articles/dandelion-taraxacum-officinale/ - Jeon, H.J. and Kang, H.J. and Jung, H.J. and Kang, Y.S. and Lim, C.J. and Kim, Y.M. and Park, E.H (2008) 'Anti-inflammatory activity of Taraxacum officinale', Journal of Ethnopharmacology, 115(1), pp. 82-88. doi:10.1016/j.jep.2007.09.006 Preclinical
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https://doi.org/10.3390/ph16030358 - Laila, U. and Kaur, J. and Sharma, K. and Singh, J. and Rasane, P. and Kaur, S. and Bhadariya, V (2025) 'Dandelion (Taraxacum officinale): A Promising Source of Nutritional and Therapeutic Compounds', Recent Advances in Food, Nutrition & Agriculture, 16(1), pp. 41-56. doi:10.2174/012772574X293072240217185616 Meta-analysis / review
https://doi.org/10.2174/012772574X293072240217185616 - Ahmadi, S. and Saberivand, A. and Jalili, C. and Asadpour, R. and Khordadmehr, M. and Saberivand, M (2023) 'Hydroalcoholic extract of Taraxacum officinale induces apoptosis and autophagy in 4T1 breast cancer cells', Veterinary Research Forum, 14(9), pp. 507-513. doi:10.30466/vrf.2023.1985987.3726 Preclinical
https://doi.org/10.30466/vrf.2023.1985987.3726 - Wirngo, F.E. and Lambert, M.N. and Jeppesen, P.B (2016) 'The Physiological Effects of Dandelion (Taraxacum officinale) in Type 2 Diabetes', The Review of Diabetic Studies, 13(2-3), pp. 113-131. doi:10.1900/RDS.2016.13.113 Meta-analysis / review
https://doi.org/10.1900/RDS.2016.13.113 - Choi, J. and Yoon, K.D. and Kim, J (2017) 'Chemical constituents from Taraxacum officinale and their alpha-glucosidase inhibitory activities', Bioorganic & Medicinal Chemistry Letters, 28(3), pp. 476-481. doi:10.1016/j.bmcl.2017.12.014 Preclinical
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https://doi.org/10.3390/molecules25225402 - Xu, P. and Xu, X. and Fotina, H. and Fotina, T (2023) 'Anti-inflammatory effects of chlorogenic acid from Taraxacum officinale on LTA-stimulated bovine mammary epithelial cells via the TLR2/NF-kB pathway', PLoS One, 18(3), pp. e0282343. doi:10.1371/journal.pone.0282343 Preclinical
https://doi.org/10.1371/journal.pone.0282343 - Kamal, F.Z. and Lefter, R. and Mihai, C.T. and Farah, H. and Ciobica, A. and Ali, A. and Radu, I. and Mavroudis, I. and Ech-Chahad, A (2022) 'Chemical Composition, Antioxidant and Antiproliferative Activities of Taraxacum officinale Essential Oil', Molecules, 27(19), pp. 6477. doi:10.3390/molecules27196477 Preclinical
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https://doi.org/10.3390/ph18050663 - Al-Eisawi, Z. and Abderrahman, S.M. and Al-khalaf, I.F. and Al-Abbassi, R. and Bustanji, Y (2020) 'Taraxacum officinale Extracts Exhibit Safe and Selective Anticancer Activity', The Natural Products Journal. doi:10.2174/2210315510999201109202255 Preclinical
https://doi.org/10.2174/2210315510999201109202255 - Nassan, M.A. and Soliman, M.M. and Ismail, S. and El‐Shazly, S.A (2018) 'Effect of Taraxacum officinale extract on PI3K/Akt pathway in DMBA-induced breast cancer in albino rats', Bioscience Reports. doi:10.1042/bsr20180334 Preclinical
https://doi.org/10.1042/bsr20180334 - Nguyen, C. and Mehaidli, A. and Baskaran, K. and Grewal, S. and Pupulin, A. and Ruvinov, I. and Scaria, B. and Parashar, K. and Vegh, C. and Pandey, S (2019) 'Dandelion Root and Lemongrass Extracts Induce Apoptosis, Enhance Chemotherapeutic Efficacy, and Reduce Tumour Xenograft Growth In Vivo in Prostate Cancer', Evidence-based Complementary and Alternative Medicine. doi:10.1155/2019/2951428 Preclinical
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.