Plant Comparison

Lesser Burdock vs Chickweed

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant ALesser BurdockArctium minusAsteraceaeFull monograph →
Plant BChickweedStellaria mediaCaryophyllaceaeFull monograph →

At a glance

Lesser Burdock and Chickweed: they share 4 indicated uses (arthritis / joint pain, eczema, inflammation (general), …); 2 pharmacological actions in common.

Lesser BurdockChickweed
Constituents33
Pharmacological actions53
Indicated uses114
Safety notes22
Cited sources2020
Indicated uses
Only Lesser Burdock
AcneCancer (anticancer research)Detox / cleansingPsoriasisSwelling / fluid retentionUrinary supportUrinary tract infection (UTI)
Shared (4)
Arthritis / joint painEczemaInflammation (general)Skin irritation
Only Chickweed
none
Pharmacological actions
Only Lesser Burdock
Alterative / depurative ('detox')Anticancer (preclinical)Diuretic
Shared (2)
Anti-inflammatoryAntioxidant
Only Chickweed
Emollient / skin-soothing

Evidence face-off — shared uses

ConditionLesser BurdockChickweedVerdict
Arthritis / joint pain1/102/10Comparable evidence
Eczema1/101/10Comparable evidence
Inflammation (general)1/102/10Comparable evidence
Skin irritation1/101/10Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Inulin (prebiotic fructan, up to ~50% of the root)[15, 16]

The major storage carbohydrate; a prebiotic fibre.

PolysaccharidesInulin
Lignans (arctigenin, arctiin)[15]

Anti-inflammatory and antioxidant constituents.

Arctigenin / arctiinLignans
Polyphenolic acids (caffeic, chlorogenic), polyacetylenes and tannins[16]

Antimicrobial and antioxidant constituents.

Chlorogenic acidCaffeic acidTannins
Flavonoids and coumarins[1]

Contribute to antioxidant and anti-inflammatory activity.

FlavonoidsCoumarins
Saponins[1]

Minor constituents; large amounts of fresh herb have anecdotally been linked to mild gastrointestinal upset, possibly related to saponin content.

Saponins
Vitamin C and minerals[1]

Nutritive constituents supporting its traditional use as a wild edible green.

Pharmacological Actions

Alterative / depurative ('detox')[15, 16, 17]

Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)

Anti-inflammatory[4, 5, 15]

Anti-inflammatory and antioxidant

Anticancer (preclinical)[6, 7, 11]

Lesser burdock (Arctium minus) leaf, flower and root extracts (rich in arctiin/arctigenin and chlorogenic acid) are cytotoxic to breast and liver cancer cells, including multidrug-resistant tumour lines (preclinical).

Antioxidant[5, 6, 10, 15]

Anti-inflammatory and antioxidant

Diuretic[15, 16]

Mild diuretic supporting elimination ('detox', traditional)

Anti-inflammatory[1, 4, 5, 7, 11, 12, 13]
Antioxidant[1, 5, 6, 11, 12, 13]
Emollient / skin-soothing[11, 12, 13]

Traditional & Indicated Uses

Acne[15, 16, 17]Traditional · 1/10

Sebaceous-gland regulator - helps balance skin oil (acne); Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)

Evidence: 1
Label: Acne
Arthritis / joint pain[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Arthritis / joint pain
Cancer (anticancer research)[6, 7, 11]Traditional · 2/10

Arctium minus extracts show dose-dependent cytotoxicity against MCF-7 and MDA-MB-231 breast cancer and HepG2 liver cancer cells and are active against both sensitive and multidrug-resistant tumour cell lines (preclinical).

Evidence: 2
Label: Cancer (anticancer research)
Detox / cleansing[15, 16, 17]Traditional · 1/10

Mild diuretic supporting elimination ('detox', traditional); Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)

Evidence: 1
Label: Detox / cleansing
Eczema[15, 16, 17]Traditional · 1/10

Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)

Evidence: 1
Label: Eczema
Inflammation (general)[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Inflammation (general)
Psoriasis[15, 16, 17]Traditional · 1/10

Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)

Evidence: 1
Label: Psoriasis
Skin irritation[15]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation
Swelling / fluid retention[15, 16]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Swelling / fluid retention
Urinary support[15, 16]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Urinary support
Urinary tract infection (UTI)[15, 16]Traditional · 1/10

inferred from diuretic action

Evidence: 1
Label: Urinary tract infection (UTI)
Arthritis / joint pain[7, 11, 12, 13]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Arthritis / joint pain
Eczema[11, 12, 13]Traditional · 1/10

inferred from emollient action

Evidence: 1
Label: Eczema
Inflammation (general)[7, 11, 12, 13]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Inflammation (general)
Skin irritation[11, 12, 13]Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1
Label: Skin irritation

Safety, Cautions & Contraindications

Safety note[16]Info

As a member of the daisy family (Asteraceae), it can cause allergic reactions in people sensitive to ragweed and related plants. The high inulin content can cause temporary bloating or gas.

Safety note[16]Caution

May lower blood sugar (caution with antidiabetic medicines) and add to diuretics; avoid medicinal doses in pregnancy.

Safety note[11, 12, 13]Caution

Don’t overdo it as food: some wild-edible-plant research flags chickweed among plants checked for oxalic acid / nitrates—fine in normal amounts, but “huge daily servings” aren’t a smart idea for everyone. (Guil et al., 1997). Kidney stones / high-oxalate diets: if you’re prone to calcium-oxalate stones, treat chickweed like other higher-oxalate greens—moderation. (Guil et al., 1997). Possible stomach upset in large amounts (nausea/diarrhea reported anecdotally; some sources link this to saponins and “too much fresh herb”). (Singh et al., 2022). Pregnancy / breastfeeding: because good human data is limited, many herbal references advise sticking to food amounts or avoiding medicinal dosing unless guided by a professional. (Singh et al., 2022).

Safety note[11, 12, 13, 14]Info

Duke (2002) notes that chickweed has primarily folkloric (score f) activity as a demulcent, emollient, and depurative. Its main medicinal applications are external — including soothing inflamed skin, eczema, and itching. No strong clinical evidence supports specific internal medicinal uses. The plant contains flavonoids and coumarins. It is considered generally safe as a dietary green and in topical preparations, though no standardized dosages are established (Duke, 2002).

External Ids

Gbif: 5393103
Wikidata: Q20996
Gbif: 5384604
Wikidata: Q158711

Botanical Description

Biennial herb closely related to greater burdock, forming a first-year rosette of large, heart-shaped, long-stalked leaves, green above and grey-woolly beneath, generally smaller than Arctium lappa. In the second year it produces a branching flowering stem with smaller purple thistle-like flower heads in a looser, more sprawling habit, each enclosed in a globe of hooked bracts that ripen into clinging burrs.[15]

Height: 0.5-1.5 m (flowering stem, second year)
Habit: Biennial herb; first-year rosette, sprawling branched second-year stem
Leaves: Large, heart-shaped, long-stalked, green above and grey-woolly beneath (smaller than A. lappa)
Flowers: Smaller purple thistle-like flower heads in a looser, sprawling arrangement, enclosed in hooked bracts
Stem: Branching, more sprawling than A. lappa (second year only)
Root: Long, fleshy first-year taproot ('wild rhubarb')
Fruit: Bristly, hooked burr enclosing small achenes
Flowering Period: July-September (second year)

Low, sprawling annual herb (Caryophyllaceae) forming mats, with weak trailing stems bearing a single line of fine hairs running up one side, switching sides at each leaf node - a key identification feature. Leaves are opposite, ovate and pointed. Tiny white, star-shaped flowers have five deeply notched petals that appear as ten, followed by a small capsule.[1]

Height: Low, sprawling/mat-forming, stems to about 40 cm
Habit: Low, sprawling, mat-forming annual herb
Leaves: Opposite, ovate, pointed
Flowers: Tiny, white, star-shaped, five deeply notched petals (appearing as ten)
Stem: Weak, trailing, with a single line of fine hairs switching sides at each node
Root: Shallow fibrous roots
Fruit: Small capsule
Flowering Period: Can flower almost year-round in mild climates, peaking spring-autumn

Habitat

A common weed of waste ground, roadsides, hedgerows and disturbed soil; native to Europe and widely naturalised in North America, where it is often the most common wild burdock species.[15]

Native to Europe, now a cosmopolitan weed found worldwide, growing in disturbed ground, gardens, cultivated land and waste places, tolerating cool, moist conditions.[1]

Harvesting

The root is dug at the end of the first growing season or early in the second spring, before flowering; leaf may be gathered through the first year. Careful identification against deadly nightshade, whose root can resemble burdock, is essential before digging.[15]

Parts: Root (and leaf)
Season: End of year one or start of year two, before flowering

The whole aerial plant is gathered fresh, ideally in spring or autumn when most tender, and used fresh or dried.[1]

Parts: Flower, Leaf, Stem
Season: Spring or autumn, when most tender

Traditional Uses

Lesser burdock is used interchangeably with the better-studied Arctium lappa in Western herbal medicine, as a traditional alterative/depurative for chronic skin conditions such as eczema, psoriasis and acne, and as a mild diuretic supporting elimination.[15, 16]

Chickweed has a long European and North American folk-medicine tradition as a cooling, soothing emollient for itchy, inflamed skin conditions such as eczema, and as a nutritious wild spring green. Modern phytochemical review confirms broad anti-inflammatory and antioxidant activity, though clinical trial evidence remains limited.[1, 11]

Preparations

Decoction (root)[15]

Dried or fresh root simmered in water as a traditional alterative and skin-support decoction.

Topical wash[15]

Cooled decoction used as a topical wash for eczema, acne and other skin irritation, reflecting the traditional external alterative use.

Fresh leaf poultice/salve[11]

Crushed fresh herb, or an infused oil/salve, applied to itchy, irritated or inflamed skin.

References

REF-0723, REF-0722, REF-0724, REF-1924, REF-1925, REF-1926, REF-1927, REF-1928, REF-1929, REF-1930, REF-1931, REF-1932, REF-1933, REF-1934
REF-0900, REF-0901, REF-0902, REF-0903, REF-0904, REF-0905, REF-0906, REF-0907, REF-0908, REF-0909

Lookalikes Review

Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-06

Dangerous Lookalikes

Safety note[18, 19, 20]Fatal
Dangerous Plant: atropa-belladonna
Confused Part: First-year taproots dug for use as food or 'burdock root tea'; the root of deadly nightshade closely resembles a burdock root and the two grow as weeds in the same rough ground.
Confusion Context: Lesser burdock (Arctium minus) is dug for its long first-year taproot, used as a vegetable and as 'burdock root tea.' Deadly nightshade (Atropa belladonna) grows as a weed in the same disturbed ground and its root closely resembles a burdock root, so belladonna root can be gathered or processed in mistake for burdock. This has caused real poisonings: a JAMA case report (Bryson et al., 1978) describes atropine poisoning from a commercial burdock root tea, and belladonna-contaminated herbal teas have caused severe anticholinergic poisoning from as little as a few milligrams of atropine. Belladonna contains tropane alkaloids (atropine, hyoscyamine, scopolamine); poisoning causes dry flushed skin, widely dilated pupils, blurred vision, fever, a racing heart, agitation, hallucinations, seizures and can be fatal, especially in children.
Distinguishing Features: Whole plant: only dig burdock when you can match the whole living plant - burdock has huge rhubarb-like heart-shaped leaves that are whitish-woolly underneath and, in its second year, the familiar hooked burrs. Deadly nightshade is a branching plant with dull green oval pointed leaves, solitary purple-brown bell-shaped flowers and shiny black cherry-sized berries., Berries (decisive if present): burdock never bears berries - it makes bristly burrs. A plant near your 'burdock' bearing shiny black berries in green star-shaped calyces is deadly nightshade - do not dig roots from that ground., Best practice: because the roots alone are hard to tell apart, do not wild-harvest burdock root unless an expert has confirmed the living plant - buy it from a reputable supplier instead.
Key Test: Identify the whole living plant before digging any root. Confirm large rhubarb-like leaves that are woolly-white underneath (and hooked burrs in the second year) for burdock. If there are shiny black berries, purple-brown bell-shaped flowers or oval pointed leaves among the plants, deadly nightshade may be present - do not dig or brew root tea from there. When in doubt, buy burdock rather than foraging the root.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Safety note[15, 16, 17, 18]Irritant
Dangerous Plant: euphorbia-peplus
Confused Part: Whole above-ground plant (stems and leaves) gathered raw from the same low, weedy, disturbed ground where chickweed is picked. Every part carries the caustic milky latex.
Confusion Context: Petty spurge (radium weed, Euphorbia peplus) is a small sprawling annual of gardens, paths and disturbed soil - the exact habitat chickweed is foraged from - and is repeatedly named by foraging authorities as the poisonous lookalike of chickweed. The hazard is chemical injury from its latex: the diterpene-ester sap (ingenol mebutate, confirmed in E. peplus by Ramsay et al. 2011) is caustic to skin, lips, mouth and especially the eye. Euphorbia latex in the eye behaves like an alkaline chemical burn and has caused keratouveitis, corneal epithelial defects, hypopyon and temporary vision loss in published case reports (Merani et al. 2007; Fleischman et al. 2012). Breaking a plant open in the hand and eating it transfers this caustic sap to lips, mouth and gut.
Distinguishing Features: SNAP TEST (decisive): petty spurge instantly bleeds a white MILKY latex from any broken stem or leaf. Chickweed NEVER produces milky sap - torn chickweed shows only clear juice and a stretchy elastic inner thread., Stem: petty spurge has a smooth, round, hairless stem. Chickweed has one distinct line of fine white hairs running up just one side of the stem, switching sides at each leaf node., Flowers: petty spurge has tiny green cup-shaped flower structures (cyathia) with no true petals. Chickweed has small white star flowers whose five petals are so deeply cleft they look like ten.
Key Test: Break a stem. If a white milky latex oozes out it is spurge - discard it and keep it away from mouth and eyes. Chickweed yields only clear juice and a stretchy inner thread, never milk.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-06
Safety note[18, 19, 20]Irritant
Dangerous Plant: lysimachia-arvensis
Confused Part: Whole leafy plant (stems and leaves) picked raw from cultivated or weedy ground, especially before flowering; all parts contain the toxic saponins.
Confusion Context: Scarlet pimpernel (Lysimachia arvensis, syn. Anagallis arvensis) is a low sprawling annual of the same disturbed weedy ground where chickweed is gathered and shares the small-leaved trailing habit, so pre-flowering shoots can be mistaken for chickweed. It contains haemolytic saponins; the University of California notes it can be toxic to livestock and humans, with toxicity ranging from virtually nontoxic to fatally toxic. Genuine lethal potential is on record: Schneider (1978) experimentally reproduced fatal nephrosis with uraemia and renal cortical necrosis by dosing sheep with the plant. The realistic human outcome from eating it in a salad is gastrointestinal upset, but it is not food.
Distinguishing Features: Stem: scarlet pimpernel has a hairless stem that is distinctly SQUARE (four-angled) in cross-section, with no line of hairs. Chickweed has a rounded stem bearing one line of fine hairs up a single side that switches sides at each node., Leaves: pimpernel leaves are stalkless (sessile) and clasp the square stem in opposite pairs. Chickweed's lower leaves have a clear stalk (petiole)., Flowers: pimpernel flowers are salmon-orange (occasionally brick-red, blue or white) with five rounded un-notched petals. Chickweed flowers are white with five deeply cleft petals looking like ten. Any salmon-orange flower rules out chickweed., Neither plant has milky sap, so the milky-latex test does NOT separate chickweed from pimpernel - use the square hairless stem, sessile opposite leaves and orange flowers instead.
Key Test: Roll the stem between your fingers. Pimpernel's stem is square-edged and hairless all round; chickweed's rounded stem carries a single line of hairs on one side that jumps sides at each node. If flowers are present, any salmon-orange flower means it is not chickweed.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-06

Dosage

Not documented

Topical salve / infusion[11, 12, 13]

Chickweed is generally used topically as a salve or poultice for skin irritation, or as a mild infusion (roughly 2-4 g dried herb per cup); large quantities as food should be moderated given its oxalate content. Educational reference only, not a prescription.

References & Sources

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    https://doi.org/10.1038/aps.2018.32
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    https://www.herbalreality.com/herb/burdock/
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    https://pubmed.ncbi.nlm.nih.gov/28612694/
  1. Oladeji, O.S., Oyebamiji, A.K (2020) 'Stellaria media (L.) Vill. - A plant with immense therapeutic potentials: phytochemistry and pharmacology', Heliyon, 6(6), pp. e04150. doi:10.1016/j.heliyon.2020.e04150 Traditional / reference
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  7. Chak, P., Kumar, S. and others (2024) 'In Vitro COX Inhibitory Activity, LC-MS Analysis and Molecular Docking Study of Silene vulgaris and Stellaria media', Cell Biochemistry and Biophysics, 83(1), pp. 1009-1020. doi:10.1007/s12013-024-01533-0 Preclinical
    https://doi.org/10.1007/s12013-024-01533-0
  8. Chidrawar, V.R., Patel, K.N., Sheth, N.R., Shiromwar, S.S. and Trivedi, P (2011) 'Antiobesity effect of Stellaria media against drug induced obesity in Swiss albino mice', Ayu, 32(4), pp. 576-584. doi:10.4103/0974-8520.96137 Preclinical
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  9. Rogozhin, E.A., Slezina, M.P., Slavokhotova, A.A., Istomina, E.A. and others (2015) 'A novel antifungal peptide from leaves of the weed Stellaria media L', Biochimie, 116, pp. 125-132. doi:10.1016/j.biochi.2015.07.014 Preclinical
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  10. Slavokhotova, A.A., Shelenkov, A.A., Andreev, Y.A. and Odintsova, T.I (2017) 'Defense peptide repertoire of Stellaria media predicted by high throughput next generation sequencing', Biochimie, 135, pp. 15-27. doi:10.1016/j.biochi.2016.12.017 Preclinical
    https://doi.org/10.1016/j.biochi.2016.12.017
  11. Chevallier, A (1996) 'The Encyclopedia of Medicinal Plants'. Traditional / reference
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  13. Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
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  15. Ramsay, J.R. and Suhrbier, A. and Aylward, J.H. and Ogbourne, S. and Cozzi, S.-J. and Poulsen, M.G. and Baumann, K.C. and Welburn, P. and Redlich, G.L. and Parsons, P.G (2011) 'The sap from Euphorbia peplus is effective against human nonmelanoma skin cancers', British Journal of Dermatology, 164(3), pp. 633-6. doi:10.1111/j.1365-2133.2010.10184.x Clinical study
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  16. Merani, R. and Sa-Ngiampornpanit, T. and Kerdraon, Y. and Billson, F. and McClellan, K.A (2007) 'Euphorbia lactea sap keratouveitis: case report and review of the literature', Cornea, 26(6), pp. 749-52. doi:10.1097/ICO.0b013e31805444e5 Clinical study
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  17. Fleischman, D. and Meyer, J.J. and Fowler, W.C (2012) 'Keratouveitis from Euphorbia cyparissias exposure is a temporal phenomenon', Clinical Ophthalmology, 6, pp. 851-3. doi:10.2147/OPTH.S32209 Clinical study
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  20. University of California Statewide IPM Program 'Scarlet Pimpernel (Anagallis arvensis) - Weed Gallery'. Available at: https://ipm.ucanr.edu/PMG/WEEDS/scarlet_pimpernel.html Traditional / reference
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Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.