Plant Comparison
Lesser Burdock vs Labrador-tea
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Lesser Burdock and Labrador-tea: they share 6 indicated uses (arthritis / joint pain, inflammation (general), skin irritation, …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Lesser Burdock | Labrador-tea | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 2/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
| Swelling / fluid retention | 1/10 | 3/10 | Stronger for Labrador-tea |
| Urinary support | 1/10 | 1/10 | Comparable evidence |
| Urinary tract infection (UTI) | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
The major storage carbohydrate; a prebiotic fibre.
Anti-inflammatory and antioxidant constituents.
Antimicrobial and antioxidant constituents.
Ledol is the characteristic, mildly toxic sesquiterpene alcohol of the leaf, particularly concentrated in fresh material.
Toxic diterpenes shared with related Ericaceae; the basis for the caution around excessive or prolonged use.
Pharmacological Actions
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
Lesser burdock (Arctium minus) leaf, flower and root extracts (rich in arctiin/arctigenin and chlorogenic acid) are cytotoxic to breast and liver cancer cells, including multidrug-resistant tumour lines (preclinical).
Traditional & Indicated Uses
Sebaceous-gland regulator - helps balance skin oil (acne); Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
Arctium minus extracts show dose-dependent cytotoxicity against MCF-7 and MDA-MB-231 breast cancer and HepG2 liver cancer cells and are active against both sensitive and multidrug-resistant tumour cell lines (preclinical).
Mild diuretic supporting elimination ('detox', traditional); Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
Safety, Cautions & Contraindications
As a member of the daisy family (Asteraceae), it can cause allergic reactions in people sensitive to ragweed and related plants. The high inulin content can cause temporary bloating or gas.
May lower blood sugar (caution with antidiabetic medicines) and add to diuretics; avoid medicinal doses in pregnancy.
Labrador tea contains ledol, a toxic sesquiterpene alcohol, particularly concentrated in fresh leaves. Excessive consumption can cause dizziness, headache, nausea, and even toxicity (especially in the related Ledum palustre). Use only in small, controlled amounts. Not recommended during pregnancy or breastfeeding. Identify plant correctly — confusion with other bog plants can be dangerous.
Duke (2002) rates Labrador tea as + (caution warranted) and notes primarily folkloric activities, with the plant acting as a diuretic, expectorant, and vulnerary. Importantly, Duke classifies it as having narcotic and deliriant potential — large doses can cause intoxication, hallucinations, and toxicity. It contains ericolin and ledol, which are potentially neurotoxic compounds. Duke emphasizes that Labrador tea should be used only with caution and at low doses, and notes that it is not appropriate for regular internal use given its toxicity profile at higher amounts (Duke, 2002).
External Ids
Botanical Description
Biennial herb closely related to greater burdock, forming a first-year rosette of large, heart-shaped, long-stalked leaves, green above and grey-woolly beneath, generally smaller than Arctium lappa. In the second year it produces a branching flowering stem with smaller purple thistle-like flower heads in a looser, more sprawling habit, each enclosed in a globe of hooked bracts that ripen into clinging burrs.[15]
Low evergreen shrub (Ericaceae), 30-100 cm tall. Leaves are narrow, leathery, with in-rolled margins and a dense, rust-coloured, woolly felt on the underside, strongly aromatic when crushed. Small white flowers are borne in terminal clusters.[4]
Habitat
A common weed of waste ground, roadsides, hedgerows and disturbed soil; native to Europe and widely naturalised in North America, where it is often the most common wild burdock species.[15]
Harvesting
The root is dug at the end of the first growing season or early in the second spring, before flowering; leaf may be gathered through the first year. Careful identification against deadly nightshade, whose root can resemble burdock, is essential before digging.[15]
Leaves and young stems are gathered, traditionally in late summer, and dried. Only small amounts are used given the plant's ledol/grayanotoxin content, and correct identification against toxic bog look-alikes (bog rosemary) is essential.[6]
Traditional Uses
Labrador tea has a long Indigenous North American and Scandinavian folk-medicine tradition as a mild diuretic and respiratory remedy, and as an aromatic tea and spice, always used in small, cautious amounts given its narcotic/toxic potential at higher doses. Modern phytochemical work confirms anti-inflammatory and antioxidant activity of its essential oil.[1]
Preparations
References
Lookalikes Review
Dangerous Lookalikes
Dosage
Not documented
Duke (2002) advises using Labrador tea only with caution and at low doses given its narcotic/deliriant potential at higher amounts; it is not appropriate for regular internal use. Educational reference only, not a prescription - use only small, occasional amounts of properly identified leaf.
References & Sources
- Ahangarpour, A., Heidari, H., Oroojan, A.A., Mirzavandi, F., Nasr Esfehani, K. and Dehghan Mohammadi, Z (2017) 'Antidiabetic, hypolipidemic and hepatoprotective effects of Arctium lappa root's hydro-alcoholic extract on nicotinamide-streptozotocin induced type 2 model of diabetes in male mice', Avicenna Journal of Phytomedicine, 7(2), pp. 169-179. Available at: https://pubmed.ncbi.nlm.nih.gov/28348972/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/28348972/ - Gao, Q., Yang, M. and Zuo, Z (2018) 'Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L', Acta Pharmacologica Sinica, 39(5), pp. 787-801. doi:10.1038/aps.2018.32 Traditional / reference
https://doi.org/10.1038/aps.2018.32 - Zeng, F., Li, Y., Zhang, X., Shen, L., Zhao, X. et al (2023) 'Immune regulation and inflammation inhibition of Arctium lappa L. polysaccharides by TLR4/NF-κB signaling pathway in cells', International Journal of Biological Macromolecules, 254, pp. 127700. doi:10.1016/j.ijbiomac.2023.127700 Preclinical
https://doi.org/10.1016/j.ijbiomac.2023.127700 - Fischer, S.P.M., Brusco, I., Camponogara, C., Piana, M., Faccin, H., Gobo, L.A., de Carvalho, L.M. and Oliveira, S.M (2017) 'Arctium minus crude extract presents antinociceptive effect in a mice acute gout attack model', Inflammopharmacology, 26(2), pp. 505-519. doi:10.1007/s10787-017-0384-6 Preclinical
https://doi.org/10.1007/s10787-017-0384-6 - Erdemoglu, N., Turan, N.N., Akkol, E.K., Sener, B. and Abacioglu, N (2008) 'Estimation of anti-inflammatory, antinociceptive and antioxidant activities of Arctium minus (Hill) Bernh. ssp. minus', Journal of Ethnopharmacology, 121(2), pp. 318-323. doi:10.1016/j.jep.2008.11.009 Preclinical
https://doi.org/10.1016/j.jep.2008.11.009 - Ilgun, S., Karatoprak, G.S., Polat, D.C., Safak, E.K., Yildiz, G., Kupeli Akkol, E. and Sobarzo-Sanchez, E (2022) 'Phytochemical Composition and Biological Activities of Arctium minus (Hill) Bernh.: A Potential Candidate as Antioxidant, Enzyme Inhibitor, and Cytotoxic Agent', Antioxidants, 11(10), pp. 1852. doi:10.3390/antiox11101852 Preclinical
https://doi.org/10.3390/antiox11101852 - Erol, E., Erol, K.F., Yanikoglu, R.S., Taskin, C., Kizilarslan Hancer, C. and Topcu, G (2024) 'Quantitative Determination of the Cytotoxic Compounds in Different Organs of Arctium minus (Hill) Bernh. by LC-HRESIMS Using Response Surface Methodology', ACS Omega, 9(40), pp. 41890-41903. doi:10.1021/acsomega.4c06644 Preclinical
https://doi.org/10.1021/acsomega.4c06644 - Malanik, M., Farkova, V., Krizova, J., Kresova, A., Smejkal, K., Kasparovsky, T. and Dadakova, K (2024) 'Comparison of Metabolic Profiles of Fruits of Arctium lappa, Arctium minus, and Arctium tomentosum', Plant Foods for Human Nutrition, 79(2), pp. 497-502. doi:10.1007/s11130-024-01175-w Preclinical
https://doi.org/10.1007/s11130-024-01175-w - Cimino, C.V., Colombo, M.L., Liggieri, C., Bruno, M. and Vairo-Cavalli, S (2015) 'Partial Molecular Characterization of Arctium minus Aspartylendopeptidase and Preparation of Bioactive Peptides by Whey Protein Hydrolysis', Journal of Medicinal Food, 18(8), pp. 856-864. doi:10.1089/jmf.2014.0101 Preclinical
https://doi.org/10.1089/jmf.2014.0101 - Kenny, O., Smyth, T.J., Walsh, D., Kelleher, C.T., Hewage, C.M. and Brunton, N.P (2014) 'Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts', Food Chemistry, 161, pp. 79-86. doi:10.1016/j.foodchem.2014.03.126 Preclinical
https://doi.org/10.1016/j.foodchem.2014.03.126 - Karadeniz, A., Alexie, G., Greten, H.J., Andersch, K. and Efferth, T (2015) 'Cytotoxicity of medicinal plants of the West-Canadian Gwich'in Native Americans towards sensitive and multidrug-resistant cancer cells', Journal of Ethnopharmacology, 168, pp. 191-200. doi:10.1016/j.jep.2015.03.052 Preclinical
https://doi.org/10.1016/j.jep.2015.03.052 - Watkins, F., Pendry, B., Sanchez-Medina, A. and Corcoran, O (2012) 'Antimicrobial assays of three native British plants used in Anglo-Saxon medicine for wound healing formulations in 10th century England', Journal of Ethnopharmacology, 144(2), pp. 408-415. doi:10.1016/j.jep.2012.09.031 Preclinical
https://doi.org/10.1016/j.jep.2012.09.031 - Abraham, E.P. and Crowfoot, D.M (1946) 'An antibacterial substance from Arctium minus and Onopordon tauricum', Nature, 158(4021), pp. 744. doi:10.1038/158744a0 Preclinical
https://doi.org/10.1038/158744a0 - Cavallito, C.J. and Kirchner, F.K (1947) 'The antibacterial principle of Arctium minus; the unsaturated lactone structure', Journal of the American Chemical Society, 69(12), pp. 3030-3032. doi:10.1021/ja01204a028 Preclinical
https://doi.org/10.1021/ja01204a028 - Herbal Reality (n.d.) 'Burdock (Arctium): Benefits, Medicinal Uses, Safety'. Available at: https://www.herbalreality.com/herb/burdock/ Traditional / reference
https://www.herbalreality.com/herb/burdock/ - Drugs.com (n.d.) 'Burdock Uses, Benefits & Dosage'. Available at: https://www.drugs.com/npp/burdock.html Traditional / reference
https://www.drugs.com/npp/burdock.html - Chan, Y.S., Cheng, L.N., Wu, J.H., Chan, E., Kwan, Y.W., Lee, S.M.Y., Leung, G.P.H., Yu, P.H.F. and Chan, S.W (2011) 'A review of the pharmacological effects of Arctium lappa (burdock)', Inflammopharmacology, 19(5), pp. 245--254. doi:10.1007/s10787-010-0062-4 Traditional / reference
https://doi.org/10.1007/s10787-010-0062-4 - Bryson, P.D. and Watanabe, A.S. and Rumack, B.H. and Murphy, R.C (1978) 'Burdock root tea poisoning. Case report involving a commercial preparation', JAMA, 239(20), pp. 2157. Available at: https://pubmed.ncbi.nlm.nih.gov/642161/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/642161/ - Berdai, M.A. and Labib, S. and Chetouani, K. and Harandou, M (2012) 'Atropa belladonna intoxication: a case report', Pan African Medical Journal, 11, pp. 72. Available at: https://pubmed.ncbi.nlm.nih.gov/22655106/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/22655106/ - Oerlemans, C. and de Vries, I. and van Riel, A.J.H.P (2017) 'Anticholinergic syndrome caused by contaminated herbal tea; acting swiftly to identify the source', Nederlands Tijdschrift voor Geneeskunde, 161, pp. D1261. Available at: https://pubmed.ncbi.nlm.nih.gov/28612694/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/28612694/
- Dampc, A. and Luczkiewicz, M (2013) 'Rhododendron tomentosum (Ledum palustre): a review of traditional use based on current research', pp. 130--143. Traditional / reference
https://scholar.google.com/scholar?q=Rhododendron%20tomentosum%20%28Ledum%20palustre%29%3A%20a%20review%20of%20traditional%20use%20based%20on%20current%20research - Jesionek, A., Kokotkiewicz, A., Mikosik-Roczynska, A., Ciesielska-Figlon, K. and others (2019) 'Chemical variability of Rhododendron tomentosum (Ledum palustre) essential oils and their pro-apoptotic effect on lymphocytes and rheumatoid arthritis synoviocytes', Fitoterapia, 139, pp. 104402. doi:10.1016/j.fitote.2019.104402 Preclinical
https://doi.org/10.1016/j.fitote.2019.104402 - Kang, J.Y., Tran, K.D., Seiff, S.R., Mack, W.P. and Lee, W.W (2017) 'Assessing the Effectiveness of Arnica montana and Rhododendron tomentosum (Ledum palustre) in the Reduction of Ecchymosis and Edema After Oculofacial Surgery: Preliminary Results', Ophthalmic Plastic and Reconstructive Surgery, 33(1), pp. 47-52. doi:10.1097/IOP.0000000000000645 Clinical study
https://doi.org/10.1097/IOP.0000000000000645 - Vengryte, M. and Raudone, L (2024) 'Phytochemical Profiling and Biological Activities of Rhododendron subsect. Ledum: Discovering the Medicinal Potential of Labrador Tea Species in the Northern Hemisphere', Plants (Basel), 13(6), pp. 901. doi:10.3390/plants13060901 Traditional / reference
https://doi.org/10.3390/plants13060901 - Iunusova, D.R., Polezhaeva, M.A. and Marchuk, E.A (2024) 'Confusing boundaries of the Labrador tea species: dispersal history explains the lack of clear species structure', Annals of Botany, 134(6), pp. 959-974. doi:10.1093/aob/mcae130 Preclinical
https://doi.org/10.1093/aob/mcae130 - Dampc, A. and Luczkiewicz, M (2014) 'Labrador tea - the aromatic beverage and spice: a review of origin, processing and safety', Journal of the Science of Food and Agriculture, 95(8), pp. 1577-1583. doi:10.1002/jsfa.6889 Traditional / reference
https://doi.org/10.1002/jsfa.6889 - Jaenson, T.G.T., Palsson, K. and Borg-Karlson, A.K (2005) 'Evaluation of extracts and oils of tick-repellent plants from Sweden', Medical and Veterinary Entomology, 19(4), pp. 345-352. doi:10.1111/j.1365-2915.2005.00578.x Preclinical
https://doi.org/10.1111/j.1365-2915.2005.00578.x - Tattje, D.H.E. and Bos, R (1981) 'Composition of essential oil of Ledum palustre', Planta Medica, 41(3), pp. 303-307. doi:10.1055/s-2007-971719 Preclinical
https://doi.org/10.1055/s-2007-971719 - Zhang, K., Wang, J., Chen, L., Li, J. and others (2019) 'Two new taraxerane-type triterpenes from Ledum palustre L', Natural Product Research, 34(19), pp. 2723-2728. doi:10.1080/14786419.2019.1586689 Preclinical
https://doi.org/10.1080/14786419.2019.1586689 - Islam, M.N., Khalil, M.I., Islam, M.A. and Gan, S.H (2013) 'Toxic compounds in honey', Journal of Applied Toxicology, 34(7), pp. 733-742. doi:10.1002/jat.2952 Traditional / reference
https://doi.org/10.1002/jat.2952 - Baananou, S., Bagdonaite, E., Marongiu, B., Piras, A. and others (2014) 'Supercritical CO2 extract and essential oil of aerial part of Ledum palustre L. - Chemical composition and anti-inflammatory activity', Natural Product Research, 29(11), pp. 999-1005. doi:10.1080/14786419.2014.965167 Preclinical
https://doi.org/10.1080/14786419.2014.965167 - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Royal Botanic Gardens, Kew (n.d.). Available at: https://powo.science.kew.org Traditional / reference
https://powo.science.kew.org - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Kirtley, Paul (2015) 'Labrador Tea - Tonic or Toxic?'. Available at: https://paulkirtley.co.uk/2015/labrador-tea-tonic-or-toxic/ Traditional / reference
https://paulkirtley.co.uk/2015/labrador-tea-tonic-or-toxic/ - Jiang, L. and Zhanxiong, L. and Fengcai, Y. and Fuli, L. and Xiaoling, S (2022) 'Third-degree atrioventricular block caused by intoxication with rhododendron leaves', Annals of Noninvasive Electrocardiology, 28(2), pp. e13012. doi:10.1111/anec.13012 Clinical study
https://doi.org/10.1111/anec.13012
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.