Omnia SanaPlant Comparison
Lesser Burdock vs Mugwort
A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.
At a glance
Lesser Burdock and Mugwort: both belong to the Asteraceae family; they share 4 indicated uses (arthritis / joint pain, cancer (anticancer research), inflammation (general), …); 3 pharmacological actions in common.
Evidence face-off — shared uses
| Condition | Lesser Burdock | Mugwort | Verdict |
|---|---|---|---|
| Arthritis / joint pain | 1/10 | 1/10 | Comparable evidence |
| Cancer (anticancer research) | 2/10 | 2/10 | Comparable evidence |
| Inflammation (general) | 1/10 | 1/10 | Comparable evidence |
| Skin irritation | 1/10 | 1/10 | Comparable evidence |
Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.
Key Constituents
The major storage carbohydrate; a prebiotic fibre.
Anti-inflammatory and antioxidant constituents.
Antimicrobial and antioxidant constituents.
Multiple undescribed and known sesquiterpenoids and triterpenoids isolated from the leaves, several with anti-inflammatory activity.
Volatile oil containing thujone and other monoterpenes; thujone content is the basis of the caution on prolonged internal use.
Antioxidant and anti-inflammatory flavonoid and coumarin constituents.
Pharmacological Actions
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
Lesser burdock (Arctium minus) leaf, flower and root extracts (rich in arctiin/arctigenin and chlorogenic acid) are cytotoxic to breast and liver cancer cells, including multidrug-resistant tumour lines (preclinical).
Artemisia vulgaris (mugwort) extracts inhibit BCR/ABL and induce apoptosis, ferroptosis and necroptosis in chronic myeloid leukaemia and breast cancer cells (preclinical).
Traditional & Indicated Uses
Sebaceous-gland regulator - helps balance skin oil (acne); Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
Arctium minus extracts show dose-dependent cytotoxicity against MCF-7 and MDA-MB-231 breast cancer and HepG2 liver cancer cells and are active against both sensitive and multidrug-resistant tumour cell lines (preclinical).
Mild diuretic supporting elimination ('detox', traditional); Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
Traditional 'alterative' / depurative for chronic skin conditions - eczema, psoriasis, acne and boils (internally and topically)
inferred from anti-inflammatory action
inferred from diuretic action
inferred from diuretic action
inferred from anti-inflammatory action
Artemisia vulgaris (mugwort) extracts inhibit BCR/ABL and induce apoptosis in chronic myeloid leukaemia cells (including imatinib-resistant), and trigger tumour-selective ferroptosis/necroptosis in breast cancer and leukaemia cells via lysosomal Ca2+ signalling (preclinical).
inferred from digestive action
inferred from antimicrobial action
inferred from anti-inflammatory action
inferred from sedative action
inferred from antispasmodic action
inferred from anti-inflammatory action
Safety, Cautions & Contraindications
As a member of the daisy family (Asteraceae), it can cause allergic reactions in people sensitive to ragweed and related plants. The high inulin content can cause temporary bloating or gas.
May lower blood sugar (caution with antidiabetic medicines) and add to diuretics; avoid medicinal doses in pregnancy.
Contains thujone; avoid high doses or prolonged use. Contraindicated in pregnancy (uterine stimulant and abortifacient). May cause allergic reactions in individuals sensitive to the Asteraceae family. Avoid in epilepsy. Not recommended for children.
Duke (2002) rates mugwort as + (use with caution) and notes abortifacient (score 1), emmenagogue, aperitif (score 1), and insecticide activities. Duke clearly flags mugwort as contraindicated in pregnancy due to well-documented abortifacient and uterotonic properties. Traditional use has been as a digestive bitter, and the plant contains volatile oils, sesquiterpene lactones, and flavonoids. Duke notes that the plant may cause allergic reactions in individuals sensitive to Asteraceae and warns against long-term use due to potential neurotoxicity from thujone-containing essential oil (Duke, 2002).
External Ids
Botanical Description
Biennial herb closely related to greater burdock, forming a first-year rosette of large, heart-shaped, long-stalked leaves, green above and grey-woolly beneath, generally smaller than Arctium lappa. In the second year it produces a branching flowering stem with smaller purple thistle-like flower heads in a looser, more sprawling habit, each enclosed in a globe of hooked bracts that ripen into clinging burrs.[15]
Tall, aromatic perennial herb with deeply lobed, dark green leaves that are distinctively silvery-white and woolly beneath. Small, dull reddish-brown to yellowish flower heads are borne in dense, branched, leafy spikes. The reddish-brown, ridged stems and the leaf's contrasting silver underside are characteristic field marks.[3]
Habitat
A common weed of waste ground, roadsides, hedgerows and disturbed soil; native to Europe and widely naturalised in North America, where it is often the most common wild burdock species.[15]
A common plant of waste ground, roadsides, hedgerows and riverbanks; native to Europe, Asia and North Africa and widely naturalised in North America.[3]
Harvesting
The root is dug at the end of the first growing season or early in the second spring, before flowering; leaf may be gathered through the first year. Careful identification against deadly nightshade, whose root can resemble burdock, is essential before digging.[15]
The flowering aerial parts (leaf and stem) are cut in summer as flowering begins and dried in a warm, shaded, airy place; the root can be dug in autumn.[3]
Traditional Uses
Mugwort is a widely used traditional bitter digestive tonic and calming nervine, and has a long reputation as an emmenagogue for menstrual complaints (reflected in its traditional use to bring on delayed menstruation, which is also why it is contraindicated in pregnancy). It has also been burned as 'moxa' in East Asian moxibustion and used as an insect repellent ('sailor's tobacco').[3]
Preparations
References
Lookalikes Review
Dangerous Lookalikes
Dosage
Not documented
Health Canada's NNHPD monograph gives 0.2-2.4 g of dried herb top, 3 times per day, for adults 18 years and older, with infusion and decoction among the accepted methods of preparation. Educational reference only, not a prescription.
Drug Class Interactions
Not documented
References & Sources
- Ahangarpour, A., Heidari, H., Oroojan, A.A., Mirzavandi, F., Nasr Esfehani, K. and Dehghan Mohammadi, Z (2017) 'Antidiabetic, hypolipidemic and hepatoprotective effects of Arctium lappa root's hydro-alcoholic extract on nicotinamide-streptozotocin induced type 2 model of diabetes in male mice', Avicenna Journal of Phytomedicine, 7(2), pp. 169-179. Available at: https://pubmed.ncbi.nlm.nih.gov/28348972/ Preclinical
https://pubmed.ncbi.nlm.nih.gov/28348972/ - Gao, Q., Yang, M. and Zuo, Z (2018) 'Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L', Acta Pharmacologica Sinica, 39(5), pp. 787-801. doi:10.1038/aps.2018.32 Traditional / reference
https://doi.org/10.1038/aps.2018.32 - Zeng, F., Li, Y., Zhang, X., Shen, L., Zhao, X. et al (2023) 'Immune regulation and inflammation inhibition of Arctium lappa L. polysaccharides by TLR4/NF-κB signaling pathway in cells', International Journal of Biological Macromolecules, 254, pp. 127700. doi:10.1016/j.ijbiomac.2023.127700 Preclinical
https://doi.org/10.1016/j.ijbiomac.2023.127700 - Fischer, S.P.M., Brusco, I., Camponogara, C., Piana, M., Faccin, H., Gobo, L.A., de Carvalho, L.M. and Oliveira, S.M (2017) 'Arctium minus crude extract presents antinociceptive effect in a mice acute gout attack model', Inflammopharmacology, 26(2), pp. 505-519. doi:10.1007/s10787-017-0384-6 Preclinical
https://doi.org/10.1007/s10787-017-0384-6 - Erdemoglu, N., Turan, N.N., Akkol, E.K., Sener, B. and Abacioglu, N (2008) 'Estimation of anti-inflammatory, antinociceptive and antioxidant activities of Arctium minus (Hill) Bernh. ssp. minus', Journal of Ethnopharmacology, 121(2), pp. 318-323. doi:10.1016/j.jep.2008.11.009 Preclinical
https://doi.org/10.1016/j.jep.2008.11.009 - Ilgun, S., Karatoprak, G.S., Polat, D.C., Safak, E.K., Yildiz, G., Kupeli Akkol, E. and Sobarzo-Sanchez, E (2022) 'Phytochemical Composition and Biological Activities of Arctium minus (Hill) Bernh.: A Potential Candidate as Antioxidant, Enzyme Inhibitor, and Cytotoxic Agent', Antioxidants, 11(10), pp. 1852. doi:10.3390/antiox11101852 Preclinical
https://doi.org/10.3390/antiox11101852 - Erol, E., Erol, K.F., Yanikoglu, R.S., Taskin, C., Kizilarslan Hancer, C. and Topcu, G (2024) 'Quantitative Determination of the Cytotoxic Compounds in Different Organs of Arctium minus (Hill) Bernh. by LC-HRESIMS Using Response Surface Methodology', ACS Omega, 9(40), pp. 41890-41903. doi:10.1021/acsomega.4c06644 Preclinical
https://doi.org/10.1021/acsomega.4c06644 - Malanik, M., Farkova, V., Krizova, J., Kresova, A., Smejkal, K., Kasparovsky, T. and Dadakova, K (2024) 'Comparison of Metabolic Profiles of Fruits of Arctium lappa, Arctium minus, and Arctium tomentosum', Plant Foods for Human Nutrition, 79(2), pp. 497-502. doi:10.1007/s11130-024-01175-w Preclinical
https://doi.org/10.1007/s11130-024-01175-w - Cimino, C.V., Colombo, M.L., Liggieri, C., Bruno, M. and Vairo-Cavalli, S (2015) 'Partial Molecular Characterization of Arctium minus Aspartylendopeptidase and Preparation of Bioactive Peptides by Whey Protein Hydrolysis', Journal of Medicinal Food, 18(8), pp. 856-864. doi:10.1089/jmf.2014.0101 Preclinical
https://doi.org/10.1089/jmf.2014.0101 - Kenny, O., Smyth, T.J., Walsh, D., Kelleher, C.T., Hewage, C.M. and Brunton, N.P (2014) 'Investigating the potential of under-utilised plants from the Asteraceae family as a source of natural antimicrobial and antioxidant extracts', Food Chemistry, 161, pp. 79-86. doi:10.1016/j.foodchem.2014.03.126 Preclinical
https://doi.org/10.1016/j.foodchem.2014.03.126 - Karadeniz, A., Alexie, G., Greten, H.J., Andersch, K. and Efferth, T (2015) 'Cytotoxicity of medicinal plants of the West-Canadian Gwich'in Native Americans towards sensitive and multidrug-resistant cancer cells', Journal of Ethnopharmacology, 168, pp. 191-200. doi:10.1016/j.jep.2015.03.052 Preclinical
https://doi.org/10.1016/j.jep.2015.03.052 - Watkins, F., Pendry, B., Sanchez-Medina, A. and Corcoran, O (2012) 'Antimicrobial assays of three native British plants used in Anglo-Saxon medicine for wound healing formulations in 10th century England', Journal of Ethnopharmacology, 144(2), pp. 408-415. doi:10.1016/j.jep.2012.09.031 Preclinical
https://doi.org/10.1016/j.jep.2012.09.031 - Abraham, E.P. and Crowfoot, D.M (1946) 'An antibacterial substance from Arctium minus and Onopordon tauricum', Nature, 158(4021), pp. 744. doi:10.1038/158744a0 Preclinical
https://doi.org/10.1038/158744a0 - Cavallito, C.J. and Kirchner, F.K (1947) 'The antibacterial principle of Arctium minus; the unsaturated lactone structure', Journal of the American Chemical Society, 69(12), pp. 3030-3032. doi:10.1021/ja01204a028 Preclinical
https://doi.org/10.1021/ja01204a028 - Herbal Reality (n.d.) 'Burdock (Arctium): Benefits, Medicinal Uses, Safety'. Available at: https://www.herbalreality.com/herb/burdock/ Traditional / reference
https://www.herbalreality.com/herb/burdock/ - Drugs.com (n.d.) 'Burdock Uses, Benefits & Dosage'. Available at: https://www.drugs.com/npp/burdock.html Traditional / reference
https://www.drugs.com/npp/burdock.html - Chan, Y.S., Cheng, L.N., Wu, J.H., Chan, E., Kwan, Y.W., Lee, S.M.Y., Leung, G.P.H., Yu, P.H.F. and Chan, S.W (2011) 'A review of the pharmacological effects of Arctium lappa (burdock)', Inflammopharmacology, 19(5), pp. 245--254. doi:10.1007/s10787-010-0062-4 Traditional / reference
https://doi.org/10.1007/s10787-010-0062-4 - Bryson, P.D. and Watanabe, A.S. and Rumack, B.H. and Murphy, R.C (1978) 'Burdock root tea poisoning. Case report involving a commercial preparation', JAMA, 239(20), pp. 2157. Available at: https://pubmed.ncbi.nlm.nih.gov/642161/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/642161/ - Berdai, M.A. and Labib, S. and Chetouani, K. and Harandou, M (2012) 'Atropa belladonna intoxication: a case report', Pan African Medical Journal, 11, pp. 72. Available at: https://pubmed.ncbi.nlm.nih.gov/22655106/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/22655106/ - Oerlemans, C. and de Vries, I. and van Riel, A.J.H.P (2017) 'Anticholinergic syndrome caused by contaminated herbal tea; acting swiftly to identify the source', Nederlands Tijdschrift voor Geneeskunde, 161, pp. D1261. Available at: https://pubmed.ncbi.nlm.nih.gov/28612694/ Clinical study
https://pubmed.ncbi.nlm.nih.gov/28612694/
- Liu, T., Chen, X., Hu, Y., Li, M., Wu, Y. et al (2022) 'Sesquiterpenoids and triterpenoids with anti-inflammatory effects from Artemisia vulgaris L', Phytochemistry, 204, pp. 113428. doi:10.1016/j.phytochem.2022.113428 Preclinical
https://doi.org/10.1016/j.phytochem.2022.113428 - Trinh, P.T.N., Truc, N.C., Danh, T.T., Trang, N.T.T., Le Hang, D.T. et al (2024) 'A study on the antioxidant, anti-inflammatory, and xanthine oxidase inhibitory activity of the Artemisia vulgaris L. extract and its fractions', Journal of Ethnopharmacology, 334, pp. 118519. doi:10.1016/j.jep.2024.118519 Preclinical
https://doi.org/10.1016/j.jep.2024.118519 - Abiri, R., Silva, A.L.M., de Mesquita, L.S.S., de Mesquita, J.W.C., Atabaki, N. et al (2018) 'Towards a better understanding of Artemisia vulgaris: Botany, phytochemistry, pharmacological and biotechnological potential', Food Research International, 109, pp. 403-415. doi:10.1016/j.foodres.2018.03.072 Traditional / reference
https://doi.org/10.1016/j.foodres.2018.03.072 - Ekiert, H., Pajor, J., Klin, P., Rzepiela, A., Slesak, H. and Szopa, A (2020) 'Significance of Artemisia vulgaris L. (Common Mugwort) in the History of Medicine and Its Possible Contemporary Applications Substantiated by Phytochemical and Pharmacological Studies', Molecules, 25(19), pp. 4415. doi:10.3390/molecules25194415 Meta-analysis / review
https://doi.org/10.3390/molecules25194415 - Soon, L., Ng, P.Q., Chellian, J., Madheswaran, T., Panneerselvam, J., Gupta, G., Nammi, S., Hansbro, N.G., Hsu, A., Dureja, H., Mehta, M., Satija, S., Hansbro, P.M., Collet, T. and Chellappan, D.K (2019) 'Therapeutic potential of Artemisia vulgaris: An insight into underlying immunological mechanisms', Journal of Environmental Pathology, Toxicology and Oncology, 38(3), pp. 205-216. doi:10.1615/JEnvironPatholToxicolOncol.2019029397 Meta-analysis / review
https://doi.org/10.1615/JEnvironPatholToxicolOncol.2019029397 - Xiao, J., Liu, P., Hu, Y., Liu, T., Guo, Y., Sun, P., Zheng, J., Ren, Z. and Wang, Y (2023) 'Antiviral activities of Artemisia vulgaris L. extract against herpes simplex virus', Chinese Medicine, 18(1), pp. 21. doi:10.1186/s13020-023-00711-1 Preclinical
https://doi.org/10.1186/s13020-023-00711-1 - Singh, N.B., Devi, M.L., Biona, T., Sharma, N., Das, S., Chakravorty, J., Mukherjee, P.K. and Rajashekar, Y (2023) 'Phytochemical Composition and Antimicrobial Activity of Essential Oil from the Leaves of Artemisia vulgaris L', Molecules, 28(5), pp. 2279. doi:10.3390/molecules28052279 Preclinical
https://doi.org/10.3390/molecules28052279 - Judzentiene, A. and Budiene, J (2018) 'Chemical Polymorphism of Essential Oils of Artemisia vulgaris Growing Wild in Lithuania', Chemistry & Biodiversity, 15(2), pp. e1700257. doi:10.1002/cbdv.201700257 Preclinical
https://doi.org/10.1002/cbdv.201700257 - Hanh, T.T.H., Vinh, L.B., Cuong, N.X. and Quang, T.H (2022) 'Two new eudesmane sesquiterpene glucosides from the aerial parts of Artemisia vulgaris', Natural Product Research, 37(9), pp. 1544-1549. doi:10.1080/14786419.2022.2025591 Preclinical
https://doi.org/10.1080/14786419.2022.2025591 - Zamarioli, L.D.S., Santos, M.R.M., Erustes, A.G., Meccatti, V.M., Pereira, T.C., Smaili, S.S., Marcucci, M.C., Oliveira, C.R., Pereira, G.J.S. and Bincoletto, C (2023) 'Artemisia vulgaris Induces Tumor-Selective Ferroptosis and Necroptosis via Lysosomal Ca2+ Signaling', Chinese Journal of Integrative Medicine, 30(6), pp. 525-533. doi:10.1007/s11655-023-3712-2 Preclinical
https://doi.org/10.1007/s11655-023-3712-2 - Chi, H.T. and Ly, B.T.K (2022) 'Artemisia vulgaris inhibits BCR/ABL and promotes apoptosis in chronic myeloid leukemia cells', Biomedical Reports, 17(6), pp. 92. doi:10.3892/br.2022.1575 Preclinical
https://doi.org/10.3892/br.2022.1575 - Tiwari, R.K., Ahmad, A., Khan, A.F., Al-Keridis, L.A., Saeed, M., Alshammari, N., Alabdallah, N.M., Ansari, I.A. and Mujeeb, F (2023) 'Ethanolic Extract of Artemisia vulgaris Leaf Promotes Apoptotic Cell Death in Non-Small-Cell Lung Carcinoma A549 Cells through Inhibition of the Wnt Signaling Pathway', Metabolites, 13(4), pp. 480. doi:10.3390/metabo13040480 Preclinical
https://doi.org/10.3390/metabo13040480 - Health Canada, Natural and Non-prescription Health Products Directorate (2026) 'Natural Health Product Monograph: Mugwort - Artemisia vulgaris'. Available at: https://webprod.hc-sc.gc.ca/nhpid-bdipsn/dbImages/mono_mugwort_english.pdf Traditional / reference
https://webprod.hc-sc.gc.ca/nhpid-bdipsn/dbImages/mono_mugwort_english.pdf - Becker, H (1986) 'Botany of European Artemisia species', pp. 1--24. Traditional / reference
https://scholar.google.com/scholar?q=Botany%20of%20European%20Artemisia%20species - Grieve, M (1931) 'A Modern Herbal'. Traditional / reference
https://scholar.google.com/scholar?q=A%20Modern%20Herbal - Kung, H.J. and Ko, W.C (2002) 'Pharmacological studies of Artemisia vulgaris', 13(2), pp. 99--108. Traditional / reference
https://scholar.google.com/scholar?q=Pharmacological%20studies%20of%20Artemisia%20vulgaris - Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition - Ghasemzadeh Rahbardar, M. and Hosseinzadeh, H (2024) 'Therapeutic potential of hypnotic herbal medicines: A comprehensive review', Phytotherapy Research, 38(6), pp. 3037-3059. doi:10.1002/ptr.8201 Meta-analysis / review
https://doi.org/10.1002/ptr.8201 - Block, K.I., Gyllenhaal, C. and Mead, M.N (2004) 'Safety and efficacy of herbal sedatives in cancer care', Integrative Cancer Therapies, 3(2), pp. 128-148. doi:10.1177/1534735404265003 Meta-analysis / review
https://doi.org/10.1177/1534735404265003 - Totally Wild UK 'Mugwort (Artemisia vulgaris) Identification'. Available at: https://totallywilduk.co.uk/2021/04/13/identify-mugwort/ Traditional / reference
https://totallywilduk.co.uk/2021/04/13/identify-mugwort/ - Stetzenbach, M. and Schnorbus, B. and Sagoschen, I. and Bleser, W. and Legner, D. and Sturer, A (2017) 'Acute Monkshood Intoxication Requiring Acute Resuscitation', Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie, 52(9), pp. 641-644. doi:10.1055/s-0043-106283 Clinical study
https://doi.org/10.1055/s-0043-106283
Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.