Plant Comparison

Agrimony vs Turkey tail

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant
Second plant
Show:
Plant AAgrimonyAgrimonia eupatoriaRosaceaeFull monograph →
Plant BTurkey tailTrametes versicolorPolyporaceaeFull monograph →

At a glance

Agrimony and Turkey tail: they share 5 indicated uses (arthritis / joint pain, cancer (anticancer research), inflammation (general), …); 3 pharmacological actions in common.

AgrimonyTurkey tail
Constituents43
Pharmacological actions86
Indicated uses118
Safety notes32
Cited sources1917
Indicated uses
Only Agrimony
Loss of appetiteBloatingBruisingDiarrhoeaIndigestionSore throat
Shared (5)
Arthritis / joint painCancer (anticancer research)Inflammation (general)Skin irritationWounds
Only Turkey tail
Cold & fluImmune supportInfection (general)
Pharmacological actions
Only Agrimony
AntidiarrhoealAstringentBitter digestive tonic / stomachicDigestive aidVulnerary (wound healing)
Shared (3)
Anti-inflammatoryAnticancer (preclinical)Antioxidant
Only Turkey tail
AntimicrobialAntiviralImmunomodulator / immune support

Evidence face-off — shared uses

ConditionAgrimonyTurkey tailVerdict
Arthritis / joint pain2/105/10Stronger for Turkey tail
Cancer (anticancer research)2/109/10Stronger for Turkey tail
Inflammation (general)2/105/10Stronger for Turkey tail
Skin irritation1/105/10Stronger for Turkey tail
Wounds2/105/10Stronger for Turkey tail

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Tannins (condensed and hydrolysable, including agrimoniin)[6, 9, 13, 14]

Responsible for the characteristic astringency.

Tannins
Flavonoids (luteolin, apigenin, quercetin and their glycosides)[9, 14, 15]

Antioxidant and anti-inflammatory constituents.

FlavonoidsGlycosidesQuercetinApigeninLuteolin
Phenolic acids[10, 14]

Contribute to antioxidant activity.

Phenolic acids
Triterpenes, volatile oil and silica[14, 15]

Minor constituents of the herb.

Essential (volatile) oilTerpenes / terpenoidsSilica
Beta-glucan polysaccharides[11, 12]

The principal immunomodulating constituents, forming the basis of PSK/PSP extracts.

Polysaccharides
Polysaccharopeptide (PSK/PSP, protein-bound polysaccharide)[12]

Protein-bound polysaccharide complex studied extensively as an adjunct immunotherapy.

Polysaccharides
Phenolic compounds and triterpenes[13]

Minor antioxidant constituents.

Phenolic compoundsTerpenes / terpenoids

Pharmacological Actions

Anti-inflammatory[1, 2, 4, 7, 11, 13, 15, 16]

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat)

Anticancer (preclinical)[17]

Agrimonia eupatoria ethanolic extract is cytotoxic to breast, colon, lung and cervical cancer cells and inhibits the PI3K/Akt/mTOR pathway (preclinical/in silico).

Antidiarrhoeal[13, 14, 15]

Astringent (relief of mild diarrhoea)

Antioxidant[1, 2, 5, 7, 10, 11, 12, 14, 18]
Astringent[13, 14, 15]

Astringent (relief of mild diarrhoea)

Bitter digestive tonic / stomachic[14, 15, 18]

Mild bitter digestive tonic (indigestion)

Digestive aid[14, 15, 18]

Mild bitter digestive tonic (indigestion)

Vulnerary (wound healing)[2, 13, 14, 19]

Vulnerary (minor skin inflammation and small superficial wounds, topical)

Anti-inflammatory[11, 12, 13]
Anticancer (preclinical)[1, 2, 3, 4, 5, 6, 9, 10, 11, 12, 13]
Antimicrobial[11, 12, 13]
Antioxidant[8, 9, 10, 11, 12, 13]
Antiviral[11, 12, 13]
Immunomodulator / immune support[1, 2, 3, 4, 5, 6, 7, 9, 11, 12, 13]

Traditional & Indicated Uses

Loss of appetite[14, 15, 18]Traditional · 2/10

inferred from bitter-tonic action

Evidence: 2
Label: Loss of appetite
Arthritis / joint pain[1, 2, 13, 15, 16]Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2
Label: Arthritis / joint pain
Bloating[14, 15, 18]Traditional · 2/10

inferred from digestive action

Evidence: 2
Label: Bloating
Bruising[2, 13, 14, 19]Traditional · 2/10

inferred from vulnerary action

Evidence: 2
Label: Bruising
Cancer (anticancer research)[17]Traditional · 2/10

Agrimonia eupatoria ethanolic extract shows dose-dependent cytotoxicity against MCF-7 (breast), HT-29 (colon), A549 (lung) and HeLa (cervical) cancer cells and inhibits the PI3K/Akt/mTOR/COX-2/MMP-2 axis (preclinical).

Evidence: 2
Label: Cancer (anticancer research)
Diarrhoea[13, 14, 15]Traditional · 1/10

Astringent (relief of mild diarrhoea)

Evidence: 1
Label: Diarrhoea
Indigestion[14, 15, 18]Traditional · 2/10

Mild bitter digestive tonic (indigestion)

Evidence: 2
Label: Indigestion
Inflammation (general)[1, 2, 13, 14, 15, 16, 19]Traditional · 2/10

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat); Vulnerary (minor skin inflammation and small superficial wounds, topical)

Evidence: 2
Label: Inflammation (general)
Skin irritation[13, 14, 15]Traditional · 1/10

inferred from astringent action

Evidence: 1
Label: Skin irritation
Sore throat[1, 2, 13, 15, 16]Traditional · 2/10

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat)

Evidence: 2
Label: Sore throat
Wounds[2, 13, 14, 19]Traditional · 2/10

Vulnerary (minor skin inflammation and small superficial wounds, topical)

Evidence: 2
Label: Wounds
Arthritis / joint pain[11, 12, 13]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Arthritis / joint pain
Cancer (anticancer research)[1, 2, 3, 4, 6, 12]Strong · 9/10

inferred from anticancer action

Evidence: 9
Label: Cancer (anticancer research)
Cold & flu[11, 12, 13]Moderate · 5/10

inferred from antiviral action

Evidence: 5
Label: Cold & flu
Immune support[11, 12, 13]Moderate · 5/10
Evidence: 5
Label: Immune support
Infection (general)[11, 12, 13]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Infection (general)
Inflammation (general)[11, 12, 13]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Inflammation (general)
Skin irritation[11, 12, 13]Moderate · 5/10

inferred from anti-inflammatory action

Evidence: 5
Label: Skin irritation
Wounds[11, 12, 13]Moderate · 5/10

inferred from antimicrobial action

Evidence: 5
Label: Wounds

Safety, Cautions & Contraindications

Safety note[13]Info

Traditional-use indication only: if diarrhoea persists longer than 3-4 days, or symptoms of mouth/throat inflammation persist beyond about a week, a doctor should be consulted.

Safety note[13]Caution

Use during pregnancy and breastfeeding is not recommended, as safety has not been established.

Safety note[13, 15]Info

Tannin-rich; very high or prolonged intake may cause gastrointestinal upset or constipation and can reduce the absorption of iron and some medicines taken at the same time.

Safety note[11, 12, 13]Caution

Generally very safe and well tolerated. Rare cases of digestive upset or allergic reaction. No significant known drug interactions at normal doses. The PSK pharmaceutical form is used safely alongside standard cancer treatments. Suitable for most adults.

Safety note[11, 12, 13, 14]Info

Duke (2002) does not include a dedicated entry for Turkey tail mushroom (Trametes versicolor) in the Handbook of Medicinal Herbs, Second Edition.

External Ids

Gbif: 3001956
Wikidata: Q156865
Gbif: 2548311
Wikidata: Q753833

Botanical Description

Slender, downy perennial herb with a basal rosette of pinnately compound leaves and a single, unbranched, upright flowering stem. The leaflets are toothed, alternating large and small, and silvery-downy beneath. Small, five-petalled, bright yellow flowers are borne closely along a slender terminal spike (raceme), opening a few at a time from the base upwards, giving the old name 'church steeples'. After flowering, small bristly, hooked burrs form that cling to clothing and animal fur for dispersal.[13, 14]

Height: 30-100 cm
Habit: Erect, downy perennial herb
Leaves: Pinnately compound, toothed leaflets of alternating large and small size, silvery-downy beneath
Flowers: Small, five-petalled, bright yellow flowers crowded on a slender terminal spike
Stem: Single, unbranched, upright, downy flowering stem
Root: Woody rootstock
Fruit: Small bristly, hooked burr that clings to clothing and fur
Flowering Period: June-September

Bracket fungus (not a true plant) forming thin, tough, fan-shaped, overlapping shelves on dead or decaying hardwood, with a velvety, concentrically zoned upper surface in bands of brown, tan, cream, blue-grey and rust, and a white, minutely pored underside.

Height: Individual brackets 2-8 cm across, forming overlapping clusters
Habit: Bracket (shelf) fungus growing directly from dead wood, in tiered, overlapping clusters
Leaves: Not applicable (fungus); the fruiting body is a thin, tough bracket
Flowers: Not applicable (fungus); reproduces via spores released from pores on the underside
Stem: No true stem; the bracket attaches directly to the wood
Root: Not applicable; mycelium threads through the wood substrate
Fruit: Fan-shaped fruiting body (bracket) with a white, densely pored underside
Flowering Period: Fruiting bodies present year-round, most abundant in autumn

Habitat

Grows in dry grassland, hedgerows, field margins, roadsides and open woodland edges on well-drained, often calcareous soils; native and common throughout Europe, temperate Asia and North Africa.[13, 14]

Grows on dead, dying or fallen hardwood logs, stumps and branches in woodlands worldwide, including Europe, Asia and North America.

Harvesting

The flowering aerial parts are cut in summer, at the start of flowering, and dried promptly in a warm, airy, shaded place.[13]

Parts: Aerial parts (flowering herb)
Season: Summer, at the start of flowering

Fresh brackets are harvested by cutting from the wood; for medicinal use the tough fruiting body is typically dried and then decocted (simmered) for a long time, or extracted, since the beneficial polysaccharides are not well-extracted by simple infusion.

Parts: Mycelium, Whole Plant
Season: Year-round, most abundant in autumn

Traditional Uses

Agrimony has a long folk history as an astringent remedy for mild diarrhoea, as a gargle for sore throats and mild mouth/throat inflammation, and as a mild bitter digestive tonic; it has also been applied topically to minor wounds and skin inflammation. It is officially recognised in the European Union herbal monograph for traditional use in mild diarrhoea and mild inflammation of the mouth or throat.[13, 14]

Turkey tail has a long history of use in traditional Chinese medicine (as yun zhi) and is one of the most researched medicinal mushrooms, with standardized polysaccharide-K (PSK) and polysaccharopeptide (PSP) extracts used clinically in Japan and China alongside conventional cancer treatment to support immune function.[11, 12, 13]

Preparations

Infusion[13]

Dried flowering herb infused in hot water, taken internally for mild diarrhoea and digestive complaints or used as a gargle/mouthwash for sore throat.

Poultice/compress[13]

Crushed or infused herb applied externally to minor wounds and skin inflammation.

Long decoction[11]

Dried fruiting body simmered in water for an extended period (often 1-2 hours) to extract the beta-glucan polysaccharides, then strained.

Standardized extract (PSK/PSP)[12]

Standardized polysaccharide-K (PSK) or polysaccharopeptide (PSP) extract, the pharmaceutical-grade forms used in clinical research.

Dosage

Infusion[13]

The EU herbal monograph gives 1.5-4 g of the comminuted herb in 250 mL (or less) of boiling water as an infusion, 2-3 times daily, in adolescents, adults and elderly. As a gargle for mild oral or throat inflammation, 1.5 g in 150 mL of boiling water 2-4 times daily, or a decoction of 3-4.5 g in 250 mL 2-3 times daily. Educational reference only, not a prescription.

Tincture[13]

The EU herbal monograph gives 1-4 mL three times daily (orally, or as a gargle for oral and throat use). Educational reference only, not a prescription.

Standardized extract[12]

Clinical research on PSK commonly uses around 3 g daily in divided doses. Educational reference only, not a prescription.

References

REF-0681, REF-0683, REF-2328, REF-2329, REF-2330, REF-2331, REF-2332, REF-2333, REF-2334, REF-2335, REF-2336, REF-2337
REF-1582, REF-1583, REF-1584, REF-1585, REF-1586, REF-1587, REF-1588, REF-1589, REF-1590, REF-1591

Lookalikes Review

Outcome: none-known
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07
Outcome: has-lookalikes
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

Dangerous Lookalikes

Not documented

Safety note[15, 16, 17]Caution
Dangerous Plant: stereum-hirsutum
Confused Part: The whole fan-shaped bracket (the concentrically zoned shelf growing on dead hardwood), especially the top surface, which looks almost identical from above.
Confusion Context: False turkey tail (Stereum hirsutum, and the near-identical Stereum ostrea) is the commonest fungus mistaken for medicinal turkey tail. Seen from above the two are near-identical: overlapping, fan-shaped, concentrically banded, fuzzy-topped brackets on dead wood. Stereum is NOT poisonous - it is simply inedible (too thin and leathery) and there are no documented poisonings. The problem is that it is a crust fungus lacking the medicinal polysaccharides of true turkey tail, so anyone who brews it gets a worthless tea. This record exists to prevent a wasted, ineffective harvest, not to warn of poisoning.
Distinguishing Features: UNDERSIDE (decisive): true turkey tail has a whitish PORE surface underneath, densely covered with tiny pores/tubes (about 2-5 per mm, visible with a hand lens). False turkey tail (Stereum) has a completely SMOOTH, poreless underside - it is a crust fungus, not a polypore., Underside colour: true turkey tail's pore surface is white to off-white. Stereum's smooth underside is typically tan, yellowish, greyish or pale reddish-brown; a coloured, non-white underside is a red flag., Texture: true turkey tail is thin and flexible; Stereum tends to be tougher, more leathery and often wavier at the margin.
Key Test: Turn the bracket over and look at the underside with a hand lens. Genuine turkey tail shows a white surface densely covered in tiny pores (roughly 2-5 per mm). If the underside is SMOOTH and poreless (and often tan/orange/brown rather than white), it is false turkey tail (Stereum) - discard it. Smooth underside = not turkey tail.
Reviewed By: Omnia Sana (owner-authorized)
Reviewed Date: 2026-07-07

References & Sources

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  2. Paluch, Z., Biriczova, L., Pallag, G., Carvalheiro Marques, E., Vargova, N. and Kmonickova, E (2020) 'The therapeutic effects of Agrimonia eupatoria L', Physiological Research, pp. S555--S571. doi:10.33549/physiolres.934641 Preclinical
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  3. Kuczmannova, A., Balazova, A., Racanska, E., Kamenikova, M., Fialova, S., Majernik, J., Nagy, M., Gal, P. and Mucaji, P (2016) 'Agrimonia eupatoria L. and Cynara cardunculus L. water infusions: comparison of anti-diabetic activities', Molecules, 21(5), pp. 564. doi:10.3390/molecules21050564 Preclinical
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  4. Huzio, N., Grytsyk, A., Raal, A., Grytsyk, L. and Koshovyi, O (2022) 'Phytochemical and pharmacological research in Agrimonia eupatoria L. herb extract with anti-inflammatory and hepatoprotective properties', Plants, 11(18), pp. 2371. doi:10.3390/plants11182371 Preclinical
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  7. Tsirigotis-Maniecka, M., Zaczynska, E., Czarny, A., Jadczyk, P., Uminska-Wasiluk, B., Gancarz, R. and Pawlaczyk-Graja, I (2023) 'Antioxidant and protective effects of the polyphenolic glycoconjugate from Agrimonia eupatoria L. herb in the prevention of inflammation in human cells', Journal of Functional Biomaterials, 14(4), pp. 182. doi:10.3390/jfb14040182 Preclinical
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  8. Kwon, D.H., Kwon, H.Y., Kim, H.J., Chang, E.J., Kim, M.B., Yoon, S.K., Song, E.Y., Yoon, D.Y., Lee, Y.H., Choi, I.S. and Choi, Y.K (2005) 'Inhibition of hepatitis B virus by an aqueous extract of Agrimonia eupatoria L', Phytotherapy Research, 19(4), pp. 355-358. doi:10.1002/ptr.1689 Preclinical
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  9. Karlinska, E., Romanowska, B. and Kosmala, M (2021) 'The aerial parts of Agrimonia procera Wallr. and Agrimonia eupatoria L. as a source of polyphenols, and especially agrimoniin and flavonoids', Molecules, 26(24), pp. 7706. doi:10.3390/molecules26247706 Preclinical
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  10. Kuczmannova, A., Gal, P., Varinska, L., Treml, J., Kovac, I., Novotny, M., Vasilenko, T., Dall'Acqua, S., Nagy, M. and Mucaji, P (2015) 'Agrimonia eupatoria L. and Cynara cardunculus L. water infusions: phenolic profile and comparison of antioxidant activities', Molecules, 20(11), pp. 20538-20550. doi:10.3390/molecules201119715 Preclinical
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  13. European Medicines Agency (HMPC) (2015) 'European Union herbal monograph on Agrimonia eupatoria L., herba (Agrimoniae herba)'. Available at: https://www.ema.europa.eu/en/medicines/herbal/agrimoniae-herba Traditional / reference
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  14. (2022) 'Agrimonia eupatoria L.: An integrative perspective on ethnomedicinal use, phenolic composition and pharmacological activity', Journal of Ethnopharmacology. doi:10.1016/j.jep.2022.115498 Traditional / reference
    https://doi.org/10.1016/j.jep.2022.115498
  15. Herbal Reality (n.d.) 'Agrimony (Agrimonia eupatoria): Benefits, Uses, Safety'. Available at: https://www.herbalreality.com/herb/agrimony/ Traditional / reference
    https://www.herbalreality.com/herb/agrimony/
  16. Lee, K.H. and Rhee, K.H (2016) 'Anti-nociceptive effect of Agrimonia eupatoria extract on a cisplatin-induced neuropathic model', African Journal of Traditional, Complementary and Alternative Medicines, 13(5), pp. 139--144. doi:10.21010/ajtcam.v13i5.18 Preclinical
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  1. Pilkington, K., Wieland, L.S., Teng, L., Jin, X.Y. and others (2022) 'Coriolus (Trametes) versicolor mushroom to reduce adverse effects from chemotherapy or radiotherapy in people with colorectal cancer', Cochrane Database of Systematic Reviews, 11(11), pp. CD012053. doi:10.1002/14651858.CD012053.pub2 Meta-analysis / review
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  3. Fritz, H., Kennedy, D.A., Ishii, M., Fergusson, D. and others (2015) 'Polysaccharide K and Coriolus versicolor extracts for lung cancer: a systematic review', Integrative Cancer Therapies, 14(3), pp. 201-211. doi:10.1177/1534735415572883 Meta-analysis / review
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  4. Tsang, K.W., Lam, C.L., Yan, C., Mak, J.C. and others (2003) 'Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell lung cancer', Respiratory Medicine, 97(6), pp. 618-624. doi:10.1053/rmed.2003.1490 Randomized trial
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  5. Ng, T.B (1998) 'A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (Basidiomycetes: Polyporaceae)', General Pharmacology, 30(1), pp. 1-4. doi:10.1016/s0306-3623(97)00076-1 Meta-analysis / review
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  6. Kowalczewska, M., Piotrowski, J., Jedrzejewski, T. and Kozak, W (2016) 'Polysaccharide peptides from Coriolus versicolor exert differential immunomodulatory effects on blood lymphocytes and breast cancer cell line MCF-7 in vitro', Immunology Letters, 174, pp. 37-44. doi:10.1016/j.imlet.2016.04.010 Preclinical
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  7. Jedrzejewski, T., Piotrowski, J., Kowalczewska, M., Wrotek, S. and Kozak, W (2015) 'Polysaccharide peptide from Coriolus versicolor induces interleukin 6-related extension of endotoxin fever in rats', International Journal of Hyperthermia, 31(6), pp. 626-634. doi:10.3109/02656736.2015.1046953 Preclinical
    https://doi.org/10.3109/02656736.2015.1046953
  8. Scarpari, M., Reverberi, M., Parroni, A., Scala, V. and others (2017) 'Tramesan, a novel polysaccharide from Trametes versicolor. Structural characterization and biological effects', PLoS One, 12(8), pp. e0171412. doi:10.1371/journal.pone.0171412 Preclinical
    https://doi.org/10.1371/journal.pone.0171412
  9. Lysakowska, P., Sobota, A. and Wirkijowska, A (2023) 'Medicinal Mushrooms: Their Bioactive Components, Nutritional Value and Application in Functional Food Production - A Review', Molecules, 28(14), pp. 5393. doi:10.3390/molecules28145393 Meta-analysis / review
    https://doi.org/10.3390/molecules28145393
  10. Wang, K.F., Sui, K.Y., Guo, C. and Liu, C.Z (2017) 'Quorum sensing molecule-farnesol increased the production and biological activities of extracellular polysaccharide from Trametes versicolor', International Journal of Biological Macromolecules, 104(Pt A), pp. 377-383. doi:10.1016/j.ijbiomac.2017.06.053 Preclinical
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  11. Chu, K.K., Ho, S.S. and Chow, A.H (2002) 'Coriolus versicolor: a medicinal mushroom with promising immunotherapeutic values', 42(9), pp. 976--984. doi:10.1177/0091270002042009004 Traditional / reference
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  12. Standish, L.J., Wenner, C.A., Sweet, E.S., Bridge, C., Nelson, A., Martzen, M., Novack, J. and Torkelson, C (2008) 'Trametes versicolor mushroom immune therapy in breast cancer', 6(3), pp. 122--128. Traditional / reference
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  13. Wasser, S.P (2011) 'Current findings, future trends, and unsolved problems in studies of medicinal mushrooms', 89(5), pp. 1323--1332. doi:10.1007/s00253-010-3067-4 Randomized trial
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  14. Duke, J.A (2002) 'Handbook of Medicinal Herbs, Second Edition'. Traditional / reference
    https://scholar.google.com/scholar?q=Handbook%20of%20Medicinal%20Herbs%2C%20Second%20Edition
  15. Macalester College, Katharine Ordway Natural History Study Area 'Turkey Tail Fungus (Trametes versicolor)'. Available at: https://www.macalester.edu/ordway/biodiversity/inventory/turkeytailfungus/ Traditional / reference
    https://www.macalester.edu/ordway/biodiversity/inventory/turkeytailfungus/
  16. Missouri Department of Conservation 'False Turkey Tail (Stereum ostrea)'. Available at: https://mdc.mo.gov/discover-nature/field-guide/false-turkey-tail Traditional / reference
    https://mdc.mo.gov/discover-nature/field-guide/false-turkey-tail
  17. Kuo, Michael 'Stereum ostrea (False Turkey Tail)'. Available at: https://www.mushroomexpert.com/stereum_ostrea.html Traditional / reference
    https://www.mushroomexpert.com/stereum_ostrea.html

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.