Plant Comparison

Agrimony vs Clove

A side-by-side comparison of two medicinal plants — every documented constituent, action, use, safety note and cited source, assembled automatically from the Omnia Sana database.

First plant

Second plant

Plant AAgrimonyAgrimonia eupatoriaRosaceaeFull monograph →

Plant BCloveSyzygium aromaticumMyrtaceaeFull monograph →

At a glance

Agrimony and Clove: they share 7 indicated uses (arthritis / joint pain, bloating, cancer (anticancer research), …); 4 pharmacological actions in common.

AgrimonyClove

Constituents43

Pharmacological actions86

Indicated uses1112

Safety notes32

Cited sources1914

Indicated uses

Only Agrimony

Loss of appetiteBruisingDiarrhoeaSore throat

Shared (7)

Arthritis / joint painBloatingCancer (anticancer research)IndigestionInflammation (general)Skin irritationWounds

Only Clove

Back painHeadacheInfection (general)Oral & throat healthPain (general)

Pharmacological actions

Only Agrimony

AntidiarrhoealAstringentBitter digestive tonic / stomachicVulnerary (wound healing)

Shared (4)

Anti-inflammatoryAnticancer (preclinical)AntioxidantDigestive aid

Only Clove

Analgesic (pain relief)Antimicrobial

Evidence face-off — shared uses

Condition	Agrimony	Clove	Verdict
Arthritis / joint pain	2/10	2/10	Comparable evidence
Bloating	2/10	1/10	Comparable evidence
Cancer (anticancer research)	2/10	2/10	Comparable evidence
Indigestion	2/10	1/10	Comparable evidence
Inflammation (general)	2/10	1/10	Comparable evidence
Skin irritation	1/10	1/10	Comparable evidence
Wounds	2/10	1/10	Comparable evidence

Evidence scores (1–10) are computed from the tier of each cited source. “Comparable” means the two scores are within one point. Follow a score to its detailed sources.

Key Constituents

Tannins (condensed and hydrolysable, including agrimoniin)^{[6, 9, 13, 14]}

Responsible for the characteristic astringency.

Tannins

Flavonoids (luteolin, apigenin, quercetin and their glycosides)^{[9, 14, 15]}

Antioxidant and anti-inflammatory constituents.

FlavonoidsGlycosidesQuercetinApigeninLuteolin

Phenolic acids^{[10, 14]}

Contribute to antioxidant activity.

Phenolic acids

Triterpenes, volatile oil and silica^{[14, 15]}

Minor constituents of the herb.

Essential (volatile) oilTerpenes / terpenoidsSilica

Essential oil (eugenol)^{[1, 2]}

Eugenol typically makes up the great majority of clove oil and is responsible for most of its analgesic, antimicrobial and anti-inflammatory activity.

Essential (volatile) oilEugenol

Flavonoids and phenolic acids^[3]

Contribute additional antioxidant activity.

FlavonoidsPhenolic acids

Tannins^[2]

Contribute mild astringency.

Tannins

Pharmacological Actions

Anti-inflammatory^{[1, 2, 4, 7, 11, 13, 15, 16]}

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat)

Anticancer (preclinical)^[17]

Agrimonia eupatoria ethanolic extract is cytotoxic to breast, colon, lung and cervical cancer cells and inhibits the PI3K/Akt/mTOR pathway (preclinical/in silico).

Antidiarrhoeal^{[13, 14, 15]}

Astringent (relief of mild diarrhoea)

Antioxidant^{[1, 2, 5, 7, 10, 11, 12, 14, 18]}

Astringent^{[13, 14, 15]}

Astringent (relief of mild diarrhoea)

Bitter digestive tonic / stomachic^{[14, 15, 18]}

Mild bitter digestive tonic (indigestion)

Digestive aid^{[14, 15, 18]}

Mild bitter digestive tonic (indigestion)

Vulnerary (wound healing)^{[2, 13, 14, 19]}

Vulnerary (minor skin inflammation and small superficial wounds, topical)

Analgesic (pain relief)^{[2, 11, 12, 13]}

Anti-inflammatory^{[2, 3, 8, 11, 12, 13]}

Anticancer (preclinical)^[10]

Antimicrobial^{[1, 2, 3, 5, 7, 11, 12, 13]}

Antioxidant^{[1, 2, 4, 6, 7, 11, 12, 13]}

Digestive aid^{[9, 11, 12, 13]}

Traditional & Indicated Uses

Loss of appetite^{[14, 15, 18]}Traditional · 2/10

inferred from bitter-tonic action

Evidence: 2

Label: Loss of appetite

Arthritis / joint pain^{[1, 2, 13, 15, 16]}Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2

Label: Arthritis / joint pain

Bloating^{[14, 15, 18]}Traditional · 2/10

inferred from digestive action

Evidence: 2

Label: Bloating

Bruising^{[2, 13, 14, 19]}Traditional · 2/10

inferred from vulnerary action

Evidence: 2

Label: Bruising

Cancer (anticancer research)^[17]Traditional · 2/10

Agrimonia eupatoria ethanolic extract shows dose-dependent cytotoxicity against MCF-7 (breast), HT-29 (colon), A549 (lung) and HeLa (cervical) cancer cells and inhibits the PI3K/Akt/mTOR/COX-2/MMP-2 axis (preclinical).

Evidence: 2

Label: Cancer (anticancer research)

Diarrhoea^{[13, 14, 15]}Traditional · 1/10

Astringent (relief of mild diarrhoea)

Evidence: 1

Label: Diarrhoea

Indigestion^{[14, 15, 18]}Traditional · 2/10

Mild bitter digestive tonic (indigestion)

Evidence: 2

Label: Indigestion

Inflammation (general)^{[1, 2, 13, 14, 15, 16, 19]}Traditional · 2/10

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat); Vulnerary (minor skin inflammation and small superficial wounds, topical)

Evidence: 2

Label: Inflammation (general)

Skin irritation^{[13, 14, 15]}Traditional · 1/10

inferred from astringent action

Evidence: 1

Label: Skin irritation

Sore throat^{[1, 2, 13, 15, 16]}Traditional · 2/10

Anti-inflammatory gargle (mild inflammation of the mouth and throat / sore throat)

Evidence: 2

Label: Sore throat

Wounds^{[2, 13, 14, 19]}Traditional · 2/10

Vulnerary (minor skin inflammation and small superficial wounds, topical)

Evidence: 2

Label: Wounds

Arthritis / joint pain^{[8, 11, 12, 13]}Traditional · 2/10

inferred from anti-inflammatory action

Evidence: 2

Label: Arthritis / joint pain

Back pain^{[11, 12, 13]}Traditional · 1/10

inferred from analgesic action

Evidence: 1

Label: Back pain

Bloating^{[11, 12, 13]}Traditional · 1/10

inferred from digestive action

Evidence: 1

Label: Bloating

Cancer (anticancer research)^[10]Traditional · 2/10

inferred from anticancer action

Evidence: 2

Label: Cancer (anticancer research)

Headache^{[11, 12, 13]}Traditional · 1/10

inferred from analgesic action

Evidence: 1

Label: Headache

Indigestion^{[11, 12, 13]}Traditional · 1/10

inferred from digestive action

Evidence: 1

Label: Indigestion

Infection (general)^{[5, 11, 12, 13]}Traditional · 2/10

inferred from antimicrobial action

Evidence: 2

Label: Infection (general)

Inflammation (general)^{[11, 12, 13]}Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1

Label: Inflammation (general)

Oral & throat health^{[11, 12, 13]}Traditional · 1/10

Evidence: 1

Label: Oral & throat health

Pain (general)^{[11, 12, 13]}Traditional · 1/10

Evidence: 1

Label: Pain (general)

Skin irritation^{[11, 12, 13]}Traditional · 1/10

inferred from anti-inflammatory action

Evidence: 1

Label: Skin irritation

Wounds^{[11, 12, 13]}Traditional · 1/10

inferred from antimicrobial action

Evidence: 1

Label: Wounds

Safety, Cautions & Contraindications

Safety note^[13]Info

Traditional-use indication only: if diarrhoea persists longer than 3-4 days, or symptoms of mouth/throat inflammation persist beyond about a week, a doctor should be consulted.

Safety note^[13]Caution

Use during pregnancy and breastfeeding is not recommended, as safety has not been established.

Safety note^{[13, 15]}Info

Tannin-rich; very high or prolonged intake may cause gastrointestinal upset or constipation and can reduce the absorption of iron and some medicines taken at the same time.

Safety note^{[11, 12, 13]}Caution

Strong and concentrated: Clove oil is very potent and should always be diluted before skin or mouth use.Dental use: Undiluted clove oil can burn gums or skin.Blood thinning: Clove may increase bleeding risk in large amounts or with anticoagulants.Pregnancy: Culinary amounts are fine; medicinal doses should be used cautiously.Children: Essential oil should be used with extra caution and diluted well.

Safety note^{[11, 12, 13, 14]}Caution

Duke (2002) rates cloves as +++ with clinical evidence (score 2) for analgesic activity — specifically, topical application of clove oil (eugenol) for dental pain is clinically validated. The plant also shows strong antimicrobial, antifungal (anti-Candida), antispasmodic, and antiviral activities at the experimental level. Commission E approves topical clove preparations for dental pain. Recommended dose: 1–5% clove oil preparation (topical) or 150 mg clove powder internally. The essential oil is irritating to mucous membranes and should not be applied undiluted to skin or mucous membranes (Duke, 2002).

External Ids

Gbif: 3001956

Wikidata: Q156865

Gbif: 3183002

Wikidata: Q26736

Botanical Description

Slender, downy perennial herb with a basal rosette of pinnately compound leaves and a single, unbranched, upright flowering stem. The leaflets are toothed, alternating large and small, and silvery-downy beneath. Small, five-petalled, bright yellow flowers are borne closely along a slender terminal spike (raceme), opening a few at a time from the base upwards, giving the old name 'church steeples'. After flowering, small bristly, hooked burrs form that cling to clothing and animal fur for dispersal.^{[13, 14]}

Height: 30-100 cm

Habit: Erect, downy perennial herb

Leaves: Pinnately compound, toothed leaflets of alternating large and small size, silvery-downy beneath

Flowers: Small, five-petalled, bright yellow flowers crowded on a slender terminal spike

Stem: Single, unbranched, upright, downy flowering stem

Root: Woody rootstock

Fruit: Small bristly, hooked burr that clings to clothing and fur

Flowering Period: June-September

Evergreen tree (Myrtaceae), 8-12 m tall (occasionally to 20 m), with a pyramidal crown. Leaves are glossy, elliptical and aromatic. Small crimson flowers are borne in terminal clusters; the unopened flower buds, picked before they open and dried, are the 'cloves' of commerce and the medicinal/culinary part used.^[2]

Height: 8-12 m (occasionally to 20 m)

Habit: Evergreen tree with a pyramidal crown

Leaves: Glossy, elliptical, aromatic

Flowers: Small, crimson, in terminal clusters; unopened buds are the harvested cloves

Stem: Woody, branching

Root: Deep woody root system

Fruit: Small drupe ("mother clove"), less commonly harvested than the flower bud

Flowering Period: Variable, often twice a year in tropical climates

Habitat

Grows in dry grassland, hedgerows, field margins, roadsides and open woodland edges on well-drained, often calcareous soils; native and common throughout Europe, temperate Asia and North Africa.^{[13, 14]}

Native to the Maluku Islands (Moluccas, the historic 'Spice Islands') of Indonesia, now cultivated throughout the tropics, notably Zanzibar, Madagascar, Sri Lanka and Indonesia, in warm, humid, well-drained tropical conditions.^[2]

Harvesting

The flowering aerial parts are cut in summer, at the start of flowering, and dried promptly in a warm, airy, shaded place.^[13]

Parts: Aerial parts (flowering herb)

Season: Summer, at the start of flowering

Unopened flower buds are hand-picked while still green-pink, just before they would open, then sun-dried until they turn dark reddish-brown - the familiar clove spice.^[2]

Parts: Flower

Season: Before the flower buds open

Traditional Uses

Agrimony has a long folk history as an astringent remedy for mild diarrhoea, as a gargle for sore throats and mild mouth/throat inflammation, and as a mild bitter digestive tonic; it has also been applied topically to minor wounds and skin inflammation. It is officially recognised in the European Union herbal monograph for traditional use in mild diarrhoea and mild inflammation of the mouth or throat.^{[13, 14]}

Clove has an ancient trade history and a long traditional use across Asian, African and European medicine as a dental analgesic (chewed or applied as oil for toothache), a digestive carminative, and an antiseptic. Modern research on its principal constituent eugenol supports strong analgesic, antimicrobial, antioxidant and anti-inflammatory activity, with clove oil remaining a recognised topical dental-pain remedy.^[2]

Preparations

Infusion^[13]

Dried flowering herb infused in hot water, taken internally for mild diarrhoea and digestive complaints or used as a gargle/mouthwash for sore throat.

Poultice/compress^[13]

Crushed or infused herb applied externally to minor wounds and skin inflammation.

Whole clove (culinary/chewed)^[2]

Whole dried flower buds chewed or infused for digestive and dental use.

Clove oil (topical, diluted)^{[11, 12, 13]}

The classic dental-pain remedy, applied to the affected tooth/gum, always diluted.

Dosage

Infusion^[13]

The EU herbal monograph gives 1.5-4 g of the comminuted herb in 250 mL (or less) of boiling water as an infusion, 2-3 times daily, in adolescents, adults and elderly. As a gargle for mild oral or throat inflammation, 1.5 g in 150 mL of boiling water 2-4 times daily, or a decoction of 3-4.5 g in 250 mL 2-3 times daily. Educational reference only, not a prescription.

Tincture^[13]

The EU herbal monograph gives 1-4 mL three times daily (orally, or as a gargle for oral and throat use). Educational reference only, not a prescription.

Clove oil / powder^{[11, 12, 13]}

Duke (2002): a 1-5% clove oil preparation topically, or about 150 mg clove powder internally. Educational reference only, not a prescription; never apply undiluted oil to skin or mucous membranes.

References

REF-0681, REF-0683, REF-2328, REF-2329, REF-2330, REF-2331, REF-2332, REF-2333, REF-2334, REF-2335, REF-2336, REF-2337

REF-1074, REF-1075, REF-1076, REF-1077, REF-1078, REF-1079, REF-1080, REF-1081, REF-1082, REF-1083

Lookalikes Review

Outcome: none-known

Reviewed By: Omnia Sana (owner-authorized)

Reviewed Date: 2026-07-07

Outcome: none-known

Reviewed By: Omnia Sana (owner-authorized)

Reviewed Date: 2026-07-07

References & Sources

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Agrimony monograph Clove monograph Compare other plants

Generated automatically from the Omnia Sana plant database and its cited sources. For educational purposes only — not medical advice. Always consult a qualified practitioner before using medicinal plants.